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Score bug

A score bug is a digital on-screen graphic which is displayed in a broadcast of a sporting event, displaying the current score and other statistics. It is similar in function to a scoreboard, and is usually placed at either the top or lower third of the television screen. == History == The concept of a persistent score bug was devised by Sky Sports head David Hill, who was dissatisfied over having to wait to see what the score was after tuning into a football match in-progress. The score bug was introduced when Sky launched its coverage of the then newly-formed English Premier League in August 1992. Hill's boss repeatedly demanded that the graphic be removed, describing it as the "stupidest thing [he] had ever seen". Hill defied the boss's demands and kept the graphic in place. ITV introduced a score bug at the start of the 1993–94 football season, and the BBC introduced a score bug towards the end of 1993. The concept was introduced to the United States by ABC Sports and ESPN during coverage of the 1994 FIFA World Cup. Their justification for the graphic was to provide a location for a rotating series of sponsor logos, in order to allow matches to air without commercial interruption. With the acquisition of rights to the National Football League (NFL) by BSkyB's American sibling Fox (a fellow venture of Rupert Murdoch), Hill became the first president of Fox Sports. Under Hill's leadership, Fox introduced a version of the score bug branded as the "Fox Box", which was part of its inaugural season of NFL coverage in 1994. Variety criticized it as an "annoying see-through clock and score graphic" and expressed concern for people "who actually watched the beginning of the game and would rather have their screen clear of graphics". Hill even received a death threat from an irate viewer, with a specific emphasis on him being a "foreigner", but the score bug soon became a ubiquitous feature for American football broadcasts, along with almost all American sports broadcasts in the years that followed. Dick Ebersol of NBC Sports initially opposed the idea of a score bug, as he thought that fans would dislike seeing more graphics on the screen and would change the channel from blowout games if the score was constantly being displayed. Since the 2010s, the on-air design and positioning of some score bugs have been influenced by the needs of Internet video (especially when viewing an event on devices with smaller screens), including bugs noticeably larger than prior iterations designed with television viewing in mind, or designs primarily kept towards the bottom-center of the screen (easing the ability for the bug to remain visible when highlights are cropped for square videos posted on social media). == Details == Score bugs used in team sports typically include the names of both teams, an abbreviation of the team's name, and/or the team's logo; for individual sports, they include the names of individual competitors. In sports where a game clock or playing periods are used, those are generally also displayed as part of the score bug. Some broadcasts also include teams' win-loss records. In 2024, ESPN experimented with adding a persistent win probability meter to its bug in Major League Baseball, which was based on input from its statisticians. === Variations === In addition to the above information, score bugs in some sports include additional information: In baseball, score bugs display the current inning, number of outs, the pitch clock if applicable, and a graphic displaying which bases are occupied; and usually include names of the current pitcher and batter, the pitcher's pitch count, and the number of balls and strikes accrued by the batter. In basketball, score bugs generally include the shot clock, the number of fouls accrued by each team, and whether a team is in the bonus. In cricket, score bugs often take the form of larger dashboards across the bottom of the screen, displaying the current team up and their number of runs, wickets, and overs, a display showing the runs scored and number of balls faced by the current batting partnership, and statistics for the opposing team's bowler (including the number of wickets scored and runs given up). In American football, score bugs usually include the play clock and the down and distance of the current play; they also incorporate graphics indicating when a penalty flag has been thrown. In ice hockey, score bugs display when a penalty or power play is in effect, and often include the number of shots on goal accrued by each team. In golf, Fox popularized the display of a persistent leaderboard graphic in the bottom-right of the screen, usually displaying the top 5. ==== Racing ==== Telecasts of automobile races often include a score bug with the current positions of participants, statistics such as distance behind the leader, and the remaining distance or number of laps. In the mid-2010s, NASCAR broadcasters such as Fox began to transition from horizontal tickers to vertical leaderboards (also referred to as "pylons", in reference to the physical scoring pylons at). The CW differentiated itself by using a horizontal display that divides the field into multiple columns along the bottom of the screen.
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Information Processing Language

Information Processing Language (IPL) is a programming language created by Allen Newell, Cliff Shaw, and Herbert A. Simon at RAND Corporation and the Carnegie Institute of Technology about 1956. Newell had the job of language specifier-application programmer, Shaw was the system programmer, and Simon had the job of application programmer-user. IPL included features to facilitate AI programming, specifically problem solving. such as lists, dynamic memory allocation, data types, recursion, functions as arguments, generators, and cooperative multitasking. IPL also introduced the concepts of symbol processing and list processing. Unfortunately, all of these innovations were cast in a difficult assembly-language style. Nonetheless, IPL-V (the only public version of IPL) ran on many computers through the mid 1960s. == Basics of IPL == An IPL computer has: A set of symbols. All symbols are addresses, and name cells. Unlike symbols in later languages, symbols consist of a character followed by a number, and are written H1, A29, 9–7, 9–100. Cell names beginning with a letter are regional, and are absolute addresses. Cell names beginning with "9-" are local, and are meaningful within the context of a single list. One list's 9-1 is independent of another list's 9–1. Other symbols (e.g., pure numbers) are internal. A set of cells. Lists are made from several cells including mutual references. Cells have several fields: P, a 3-bit field used for an operation code when the cell is used as an instruction, and unused when the cell is data. Q, a 3-valued field used for indirect reference when the cell is used as an instruction, and unused when the cell is data. SYMB, a symbol used as the value in the cell. A set of primitive processes, which would be termed primitive functions in modern languages. The data structure of IPL is the list, but lists are more intricate structures than in many languages. A list consists of a singly linked sequence of symbols, as might be expected—plus some description lists, which are subsidiary singly linked lists interpreted as alternating attribute names and values. IPL provides primitives to access and mutate attribute value by name. The description lists are given local names (of the form 9–1). So, a list named L1 containing the symbols S4 and S5, and described by associating value V1 to attribute A1 and V2 to A2, would be stored as follows. 0 indicates the end of a list; the cell names 100, 101, etc. are automatically generated internal symbols whose values are irrelevant. These cells can be scattered throughout memory; only L1, which uses a regional name that must be globally known, needs to reside in a specific place. IPL is an assembly language for manipulating lists. It has a few cells which are used as special-purpose registers. H1, for example, is the program counter. The SYMB field of H1 is the name of the current instruction. However, H1 is interpreted as a list; the LINK of H1 is, in modern terms, a pointer to the beginning of the call stack. For example, subroutine calls push the SYMB of H1 onto this stack. H2 is the free-list. Procedures which need to allocate memory grab cells off of H2; procedures which are finished with memory put it on H2. On entry to a function, the list of parameters is given in H0; on exit, the results should be returned in H0. Many procedures return a Boolean result indicating success or failure, which is put in H5. Ten cells, W0-W9, are reserved for public working storage. Procedures are "morally bound" (to quote the CACM article) to save and restore the values of these cells. There are eight instructions, based on the values of P: subroutine call, push/pop S to H0; push/pop the symbol in S to the list attached to S; copy value to S; conditional branch. In these instructions, S is the target. S is either the value of the SYMB field if Q=0, the symbol in the cell named by SYMB if Q=1, or the symbol in the cell named by the symbol in the cell named by SYMB if Q=2. In all cases but conditional branch, the LINK field of the cell tells which instruction to execute next. IPL has a library of some 150 basic operations. These include such operations as: Test symbols for equality Find, set, or erase an attribute of a list Locate the next symbol in a list; insert a symbol in a list; erase or copy an entire list Arithmetic operations (on symbol names) Manipulation of symbols; e.g., test if a symbol denotes an integer, or make a symbol local I/O operations "Generators", which correspond to iterators and filters in functional programming. For example, a generator may accept a list of numbers and produce the list of their squares. Generators could accept suitably designed functions—strictly, the addresses of code of suitably designed functions—as arguments. == History == IPL was first utilized to demonstrate that the theorems in Principia Mathematica which were proven laboriously by hand, by Bertrand Russell and Alfred North Whitehead, could in fact be proven by computation. According to Simon's autobiography Models of My Life, this application was originally developed first by hand simulation, using his children as the computing elements, while writing on and holding up note cards as the registers which contained the state variables of the program. IPL was used to implement several early artificial intelligence programs, also by the same authors: the Logic Theorist (1956), the General Problem Solver (1957), and their computer chess program NSS (1958). Several versions of IPL were created: IPL-I (never implemented), IPL-II (1957 for JOHNNIAC), IPL-III (existed briefly), IPL-IV, IPL-V (1958, for IBM 650, IBM 704, IBM 7090, Philco model 212, many others. Widely used). IPL-VI was a proposal for an IPL hardware. A co-processor “IPL-VC” for the CDC 3600 at Argonne National Libraries was developed which could run IPL-V commands. It was used to implement another checker-playing program. This hardware implementation did not improve running times sufficiently to “compete favorably with a language more directly oriented to the structure of present-day machines”. IPL was soon displaced by Lisp, which had much more powerful features, a simpler syntax, and the benefit of automatic garbage collection. == Legacy to computer programming == IPL arguably introduced several programming language features: List manipulation—but only lists of atoms, not general lists Property lists—but only when attached to other lists Higher-order functions—while assembly programming had always allowed computing with the addresses of functions, IPL was an early attempt to generalize this property of assembly language in a principled way Computation with symbols—though symbols have a restricted form in IPL (letter followed by number) Virtual machine Many of these features were generalized, rationalized, and incorporated into Lisp and from there into many other programming languages during the next several decades.
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Stanford Research Institute Problem Solver

The Stanford Research Institute Problem Solver, known by its acronym STRIPS, is an automated planner developed by Richard Fikes and Nils Nilsson in 1971 at SRI International. The same name was later used to refer to the formal language of the inputs to this planner. This language is the base for most of the languages for expressing automated planning problem instances in use today; such languages are commonly known as action languages. This article only describes the language, not the planner. == Definition == A STRIPS instance is composed of: An initial state; The specification of the goal states – situations that the planner is trying to reach; A set of actions. For each action, the following are included: preconditions (what must be established before the action is performed); postconditions (what is established after the action is performed). Mathematically, a STRIPS instance is a quadruple ⟨ P , O , I , G ⟩ {\displaystyle \langle P,O,I,G\rangle } , in which each component has the following meaning: P {\displaystyle P} is a set of conditions (i.e., propositional variables); O {\displaystyle O} is a set of operators (i.e., actions); each operator is itself a quadruple ⟨ α , β , γ , δ ⟩ {\displaystyle \langle \alpha ,\beta ,\gamma ,\delta \rangle } , each element being a set of conditions. These four sets specify, in order, which conditions must be true for the action to be executable, which ones must be false, which ones are made true by the action and which ones are made false; I {\displaystyle I} is the initial state, given as the set of conditions that are initially true (all others are assumed false); G {\displaystyle G} is the specification of the goal state; this is given as a pair ⟨ N , M ⟩ {\displaystyle \langle N,M\rangle } , which specify which conditions are true and false, respectively, in order for a state to be considered a goal state. A plan for such a planning instance is a sequence of operators that can be executed from the initial state and that leads to a goal state. Formally, a state is a set of conditions: a state is represented by the set of conditions that are true in it. Transitions between states are modeled by a transition function, which is a function mapping states into new states that result from the execution of actions. Since states are represented by sets of conditions, the transition function relative to the STRIPS instance ⟨ P , O , I , G ⟩ {\displaystyle \langle P,O,I,G\rangle } is a function succ : 2 P × O → 2 P , {\displaystyle \operatorname {succ} :2^{P}\times O\rightarrow 2^{P},} where 2 P {\displaystyle 2^{P}} is the set of all subsets of P {\displaystyle P} , and is therefore the set of all possible states. The transition function succ {\displaystyle \operatorname {succ} } for a state C ⊆ P {\displaystyle C\subseteq P} , can be defined as follows, using the simplifying assumption that actions can always be executed but have no effect if their preconditions are not met: The function succ {\displaystyle \operatorname {succ} } can be extended to sequences of actions by the following recursive equations: succ ⁡ ( C , [ ] ) = C {\displaystyle \operatorname {succ} (C,[\ ])=C} succ ⁡ ( C , [ a 1 , a 2 , … , a n ] ) = succ ⁡ ( succ ⁡ ( C , a 1 ) , [ a 2 , … , a n ] ) {\displaystyle \operatorname {succ} (C,[a_{1},a_{2},\ldots ,a_{n}])=\operatorname {succ} (\operatorname {succ} (C,a_{1}),[a_{2},\ldots ,a_{n}])} A plan for a STRIPS instance is a sequence of actions such that the state that results from executing the actions in order from the initial state satisfies the goal conditions. Formally, [ a 1 , a 2 , … , a n ] {\displaystyle [a_{1},a_{2},\ldots ,a_{n}]} is a plan for G = ⟨ N , M ⟩ {\displaystyle G=\langle N,M\rangle } if F = succ ⁡ ( I , [ a 1 , a 2 , … , a n ] ) {\displaystyle F=\operatorname {succ} (I,[a_{1},a_{2},\ldots ,a_{n}])} satisfies the following two conditions: N ⊆ F {\displaystyle N\subseteq F} M ∩ F = ∅ {\displaystyle M\cap F=\varnothing } == Extensions == The above language is actually the propositional version of STRIPS; in practice, conditions are often about objects: for example, that the position of a robot can be modeled by a predicate A t {\displaystyle At} , and A t ( r o o m 1 ) {\displaystyle At(room1)} means that the robot is in Room1. In this case, actions can have free variables, which are implicitly existentially quantified. In other words, an action represents all possible propositional actions that can be obtained by replacing each free variable with a value. The initial state is considered fully known in the language described above: conditions that are not in I {\displaystyle I} are all assumed false. This is often a limiting assumption, as there are natural examples of planning problems in which the initial state is not fully known. Extensions of STRIPS have been developed to deal with partially known initial states. == A sample STRIPS problem == A monkey is at location A in a lab. There is a box in location C. The monkey wants the bananas that are hanging from the ceiling in location B, but it needs to move the box and climb onto it in order to reach them. Initial state: At(A), Level(low), BoxAt(C), BananasAt(B) Goal state: Have(bananas) Actions: // move from X to Y _Move(X, Y)_ Preconditions: At(X), Level(low) Postconditions: not At(X), At(Y) // climb up on the box _ClimbUp(Location)_ Preconditions: At(Location), BoxAt(Location), Level(low) Postconditions: Level(high), not Level(low) // climb down from the box _ClimbDown(Location)_ Preconditions: At(Location), BoxAt(Location), Level(high) Postconditions: Level(low), not Level(high) // move monkey and box from X to Y _MoveBox(X, Y)_ Preconditions: At(X), BoxAt(X), Level(low) Postconditions: BoxAt(Y), not BoxAt(X), At(Y), not At(X) // take the bananas _TakeBananas(Location)_ Preconditions: At(Location), BananasAt(Location), Level(high) Postconditions: Have(bananas) == Complexity == Deciding whether any plan exists for a propositional STRIPS instance is PSPACE-complete. Various restrictions can be enforced in order to decide if a plan exists in polynomial time or at least make it an NP-complete problem. == Macro operator == In the monkey and banana problem, the robot monkey has to execute a sequence of actions to reach the banana at the ceiling. A single action provides a small change in the game. To simplify the planning process, it make sense to invent an abstract action, which isn't available in the normal rule description. The super-action consists of low level actions and can reach high-level goals. The advantage is that the computational complexity is lower, and longer tasks can be planned by the solver. Identifying new macro operators for a domain can be realized with genetic programming. The idea is, not to plan the domain itself, but in the pre-step, a heuristics is created that allows the domain to be solved much faster. In the context of reinforcement learning, a macro-operator is called an option. Similar to the definition within AI planning, the idea is, to provide a temporal abstraction (span over a longer period) and to modify the game state directly on a higher layer.
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LG ThinQ

LG ThinQ (pronounced as "think-cue"; sometimes known as LG webOS) is a smart home and artificial intelligence brand launched by LG Electronics in 2017, featuring products that are equipped with voice control and artificial intelligence technology. The brand was originally launched for home appliances and consumer electronics, such as televisions, smart home devices, mobile devices, refrigerators, air conditioners and related services. The name was first used in 2011 for LG's THINQ-branded smart appliances, which were introduced at the Consumer Electronics Show in Las Vegas. In December 2017, LG announced ThinQ as a unified brand for artificial intelligence-enabled home appliances, consumer electronics and services.In February 2018, LG announced the LG V30S ThinQ, which is the first phone to have the "ThinQ" branding. == History == The branding was first introduced in 2011 in the Consumer Electronics Show (CES) in Las Vegas as THINQ. The first ThinQ product was a smart refrigerator, with features such as smart savings options, food management system, washing machine, oven and robotic vacuum cleaner and different software in the LCD screen on the fridge. The unified branding was then officially launched as ThinQ at CES 2017 as an artificial intelligence-based brand for all their smart products. The company announced DeepThinQ, a deep-learning technology for connected products, and later opened an Artificial Intelligence Lab in Seoul to coordinate research involving voice, video, sensors and machine learning. In December 2017, LG announced ThinQ as a brand designation for home appliances, consumer electronics, and services incorporating artificial intelligence, applied to its 2018 product lineup. In 2018, LG extended the ThinQ brand to smartphones with the LG V30S ThinQ. The phone used ThinQ branding for AI camera features, including image recognition and shooting-mode recommendations. That year, LG also used ThinQ branding on televisions with smart-assistant features, as manufacturers increasingly added voice assistants to TV platforms. In 2022, LG first introduced ThinQ UP, a software-upgradable appliance concept that allows compatible appliances to receive new features through the ThinQ app. The program included appliances such as refrigerators, washing machines, dryers, ovens and dishwashers, and was covered as part of a wider move toward upgradeable connected appliances. In 2024, LG introduced ThinQ ON, an AI-powered smart home hub designed to connect LG appliances and other smart home devices. It expanded ThinQ from an appliance-control platform into a broader smart home system. == Platform an app == LG ThinQ operates as a smart home platform and mobile app for connecting compatible LG appliances and consumer electronics. The app is used to control and monitor supported products, including kitchen appliances, laundry appliances, air purifiers, vacuum cleaners and televisions. Depending on the product and market, the ThinQ app can provide remote control, status monitoring, downloadable appliance cycles, diagnostic support, maintenance alerts and software-based feature updates. In 2024, LG introduced ThinQ ON as a hub for the ThinQ platform. The device supports Matter, Thread and Wi-Fi connectivity and includes a built-in voice assistant. The Verge described the product as part of LG's effort to expand ThinQ from an appliance-control platform into a broader smart home system competing with platforms such as Samsung SmartThings and Apple Home. == Features == LG ThinQ products use connected-device features, voice control to interact with users, and use sensor data and different features such as product recognition and learning engine technologies to enhance their abilities. Deep ThinQ (or LG ThinQ AI) was introduced as LG's own AI platform. It was reported that it could engage in two-way conversations with users and could educate itself according to users' behaviour patterns and habits. At the 2017 ThinQ launch, LG said the brand would cover products and services using artificial intelligence technologies from LG and partner companies. ThinQ features vary by product category. On appliances, the platform may support remote operation, product-status notifications, downloaded cycles and diagnostic functions. On televisions, ThinQ branding has been associated with voice-control and smart-assistant features. In 2018, LG ThinQ-branded TVs added support for Google Assistant and Alexa voice commands. As of August 30, 2018, LG's ThinQ products now communicate with each other for tasks such as going to an event or following a recipe. They have sensors for communicating with other ThinQ devices and appliances. == Products == LG ThinQ branding and connectivity features have been used across several LG product categories, including home appliances, televisions, air conditioners and mobile devices. Home appliances LG has applied ThinQ branding and app connectivity to home appliances such as refrigerators, washing machines, dryers, dishwashers, cooking appliances, air purifiers and vacuum cleaners. Through the ThinQ app, compatible appliances can be monitored or controlled remotely. Some compatible appliances can also receive downloadable cycles, diagnostic support, maintenance alerts and software-based feature updates through ThinQ UP. Televisions and home entertainment LG has used ThinQ branding on smart televisions and other home entertainment products. In 2018, LG ThinQ-branded televisions added support for smart-assistant voice commands, including Google Assistant. Smartphones LG G6 (ThinQ branding was added to startup screen in an update) LG V30 (ThinQ branding was added to startup screen in an update) LG V30S ThinQ LG V35 ThinQ LG G7 ThinQ LG V40 ThinQ LG G8 ThinQ LG G8s ThinQ LG G8x ThinQ LG V50 ThinQ LG V60 ThinQ LG Velvet (Generally considered a ThinQ product in other countries)
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DeepRoute.ai

DeepRoute.ai (Chinese: 元戎启行) is a Chinese autonomous driving company founded in 2019 and headquartered in Shenzhen, China. The company develops full-stack self-driving solutions including perception, decision-making, and control systems. == History == DeepRoute.ai was founded in February 2019 in Shenzhen, China, by Zhou Guang (周光), who serves as the company's CEO. In September 2019, the company collaborated with Dongfeng for a live-streamed autonomous driving demonstration. In October 2019, during the 7th Military World Games, DeepRoute.ai conducted Robotaxi demonstration operations. In November 2019, it obtained an intelligent connected vehicle road test permit for public roads in Shenzhen. In October 2020, DeepRoute.ai signed an "Autonomous Driving Leadership Project" with Dongfeng to build one of China's largest autonomous fleets. In August 2020, DeepRoute.ai announced its partnership with Cao Cao Mobility, a Geely-backed ride-hailing company, to test Robotaxis in Hangzhou for daily operations, planning to provide Robotaxis during the 2022 Asian Games. In September 2021, DeepRoute.ai secured US$300 million in a Series B funding round led by Alibaba. In December 2021, the company unveiled its DeepRoute-Driver 2.0, an L4-level autonomous driving solution comprising five solid-state lidar sensors, eight cameras, a proprietary computing system and an optional millimeter-wave radar. with a production cost of under US$10,000. In June 2022, it partnered with Deppon Express to provide autonomous light truck freight transfer services. In March 2023, the company launched its high-precision map-free intelligent driving solution, DeepRoute-Driver 3.0. In November 2024, Great Wall Motor announced a $100 million Series C funding round for Deeproute. With this, Deeproute has completed five rounds of financing, raising a cumulative total of over $500 million. Its shareholders include Fosun RZ Capital, Yunqi Partners, Alibaba, Vision Plus Capital, and Dongfeng, among others. In the same month, Deeproute.ai emphasised that they were in "deep cooperation" with Nvidia and spoke on being part of the first batch of companies in China to get a hold of Nvidia's newer Thor chip for cars which will be used in a new system released next year. This new system will help manage more complex driving scenarios through visual cues. == Products == === VLA Model === VLA Model is a Vision–language–action model designed for autonomous driving systems. It integrates visual perception, semantic understanding, and action decision-making into a unified framework, aiming to enhance the safety and adaptability of advanced driver-assistance systems (ADAS) in complex road environments. The model was officially launched on August 26, 2025, as the core of DeepRoute.ai's DeepRoute IO 2.0 platform. The VLA model is characterized by its "visual-language-action" architecture, which incorporates a chain-of-thought (CoT) reasoning capability inspired by large language models. This design is intended to address the "black box" limitations of traditional end-to-end autonomous driving systems by enabling the model to analyze information, infer causality, and make decisions in a more transparent and interpretable manner. === Appliance === The company has partnered with several automakers including Dongfeng Motor Corporation and Geely to develop and test autonomous vehicles.
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AlphaFold

AlphaFold is an artificial intelligence (AI) program developed by DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018) placed first in the overall rankings of the 13th Critical Assessment of Structure Prediction (CASP) in December 2018. It was particularly successful at predicting the most accurate structures for targets rated as most difficult by the competition organizers, where no existing template structures were available from proteins with partially similar sequences. AlphaFold 2 (2020) repeated this placement in the CASP14 competition in November 2020. It achieved a level of accuracy much higher than any other entry. It scored above 90 on CASP's global distance test (GDT) for approximately two-thirds of the proteins, a test measuring the similarity between a computationally predicted structure and the experimentally determined structure, where 100 represents a complete match. The inclusion of metagenomic data has improved the quality of the prediction of multiple sequence alignments. One of the biggest sources of the training data was the custom-built Big Fantastic Database of 65,983,866 protein families, represented as multiple sequence alignments and Hidden Markov models, covering 2,204,359,010 protein sequences from reference databases, metagenomes, and metatranscriptomes. AlphaFold 2's results at CASP14 were described as "astounding" and "transformational". However, some researchers noted that the accuracy was insufficient for a third of its predictions, and that it did not reveal the underlying mechanism or rules of protein folding for the protein folding problem, which remains unsolved. Despite this, the technical achievement was widely recognized. On 15 July 2021, the AlphaFold 2 paper was published in Nature as an advance access publication alongside open source software and a searchable database of species proteomes. As of November 2025, the paper had been cited nearly 43,000 times. AlphaFold 3 was announced on 8 May 2024. It can predict the structure of complexes created by proteins with DNA, RNA, various ligands, and ions. The new prediction method shows a minimum 50% improvement in accuracy for protein interactions with other molecules compared to existing methods. Demis Hassabis and John Jumper shared one half of the 2024 Nobel Prize in Chemistry, awarded "for protein structure prediction," while the other half went to David Baker "for computational protein design." Hassabis and Jumper had previously won the Breakthrough Prize in Life Sciences and the Albert Lasker Award for Basic Medical Research in 2023 for their leadership of the AlphaFold project. == Background == Proteins consist of chains of amino acids which spontaneously fold to form the three dimensional (3-D) structures of the proteins. The 3-D structure is crucial to understanding the biological function of the protein. Protein structures can be determined experimentally through techniques such as X-ray crystallography, cryo-electron microscopy and nuclear magnetic resonance (NMR), which are all expensive and time-consuming. Such efforts, using the experimental methods, have identified the structures of about 170,000 proteins over the last 60 years, while there are over 200 million known proteins across all life forms. Over the years, researchers have applied numerous computational methods to predict the 3D structures of proteins from their amino acid sequences, accuracy of such methods in best possible scenario is close to experimental techniques (NMR) by the use of homology modeling based on molecular evolution. CASP, which was launched in 1994 to challenge the scientific community to produce their best protein structure predictions, found that GDT scores of only about 40 out of 100 can be achieved for the most difficult proteins by 2016. AlphaFold started competing in the 2018 CASP using an artificial intelligence (AI) deep learning technique. == Algorithm == DeepMind is known to have trained the program on over 170,000 protein structures from the Protein Data Bank, a public repository of protein sequences and structures. The program uses a form of attention network, a deep learning technique that focuses on having the AI identify parts of a larger problem, then piece it together to obtain the overall solution. The overall training was conducted on processing power between 100 and 200 GPUs. === AlphaFold 1 (2018) === AlphaFold 1 (2018) was built on work developed by various teams in the 2010s, work that looked at the large databases of related protein sequences now available from many different organisms (most without known 3D structures), to try to find changes at different residues (peptides) that appeared to be correlated, even though the residues were not consecutive in the main chain. Such correlations suggest that the residues may be close to each other physically, even though not close in the sequence, allowing a contact map to be estimated. Building on recent work prior to 2018, AlphaFold 1 extended this by estimating a probability distribution for the distances between residues, effectively transforming the contact map into a distance map. It also used more advanced learning methods than previously to develop the inference. The code was not made publicly available, except to run on sequences of proteins in the 2018 CASP competition. === AlphaFold 2 (2020) === The 2020 version of the program (AlphaFold 2, 2020) is significantly different from the original version that won CASP 13 in 2018, according to the team at DeepMind. AlphaFold 1 used a number of separately trained modules to produce a guide potential, which was then combined with a physics-based energy potential. AlphaFold 2 replaced this with a system of interconnected sub-networks, forming a single, differentiable, end-to-end model based on pattern recognition. This model was trained in an integrated manner. After the neural network's prediction converges, a final refinement step applies local physical constraints using energy minimization based on the AMBER force field. This step only slightly adjusts the predicted structure. A key part of the 2020 system are two modules, believed to be based on a transformer design, which are used to progressively refine a vector of information for each relationship (or "edge" in graph-theory terminology) between an amino acid residue of the protein and another amino acid residue (these relationships are represented by the array shown in green); and between each amino acid position and each different sequences in the input sequence alignment (these relationships are represented by the array shown in red). Internally these refinement transformations contain layers that have the effect of bringing relevant data together and filtering out irrelevant data (the "attention mechanism") for these relationships, in a context-dependent way, learned from training data. These transformations are iterated, the updated information output by one step becoming the input of the next, with the sharpened residue/residue information feeding into the update of the residue/sequence information, and then the improved residue/sequence information feeding into the update of the residue/residue information. As the iteration progresses, according to one report, the "attention algorithm ... mimics the way a person might assemble a jigsaw puzzle: first connecting pieces in small clumps—in this case clusters of amino acids—and then searching for ways to join the clumps in a larger whole." The output of these iterations then informs the final structure prediction module, which also uses transformers, and is itself then iterated. In an example presented by DeepMind, the structure prediction module achieved a correct topology for the target protein on its first iteration, scored as having a GDT_TS of 78, but with a large number (90%) of stereochemical violations – i.e. unphysical bond angles or lengths. With subsequent iterations the number of stereochemical violations fell. By the third iteration the GDT_TS of the prediction was approaching 90, and by the eighth iteration the number of stereochemical violations was approaching zero. The training data was originally restricted to single peptide chains. However, the October 2021 update, named AlphaFold-Multimer, included protein complexes in its training data. DeepMind stated this update succeeded about 70% of the time at accurately predicting protein-protein interactions. === AlphaFold 3 (2024) === Announced on 8 May 2024, AlphaFold 3 was co-developed by Google DeepMind and Isomorphic Labs, both subsidiaries of Alphabet. AlphaFold 3 is not limited to proteins, as it can also predict the structures of protein complexes with DNA, RNA, post-translational modifications and selected ligands and ions. AlphaFold 3 introduces the "Pairformer," a deep learning architecture inspired by the transformer, which is considered similar to, but si
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PyTorch

PyTorch is an open-source deep learning library, originally developed by Meta Platforms and currently developed with support from the Linux Foundation. The successor to Torch, PyTorch provides a high-level API that builds upon optimised, low-level implementations of deep learning algorithms and architectures, such as the Transformer, or SGD. Notably, this API simplifies model training and inference to a few lines of code. PyTorch allows for automatic parallelization of training and, internally, implements CUDA bindings that speed training further by leveraging GPU resources. PyTorch utilises the tensor as a fundamental data type, similarly to NumPy. Training is facilitated by a reversed automatic differentiation system, Autograd, that constructs a directed acyclic graph of the operations (and their arguments) executed by a model during its forward pass. With a loss, backpropagation is then undertaken. As of 2025, PyTorch remains one of the most popular deep learning libraries, alongside others such as TensorFlow and Keras. It can be installed using Anaconda package managers. A number of commercial deep learning architectures are built on top of PyTorch, including ChatGPT, Tesla Autopilot, Uber's Pyro, and Hugging Face's Transformers. == History == In 2001, Torch was written and released under a GPL. It was a machine-learning library written in C++ and CUDA, supporting methods including neural networks, support vector machines (SVM), hidden Markov models, etc. Around 2010, it was rewritten by Ronan Collobert, Clement Farabet and Koray Kavuckuoglu. This was known as Torch7 or LuaTorch. This was written so that the backend was in C and the frontend was in Lua. In mid-2016, some developers refactored it to decouple the frontend and the backend, with strong influence from torch-autograd and Chainer. In turn, torch-autograd was influenced by HIPS/autograd. Development on Torch7 ceased in 2018 and was subsumed by the PyTorch project. Meta (formerly known as Facebook) operates both PyTorch and Convolutional Architecture for Fast Feature Embedding (Caffe2), but models defined by the two frameworks were mutually incompatible. The Open Neural Network Exchange (ONNX) project was created by Meta and Microsoft in September 2017 to decouple deep learning frameworks from hardware-specific runtimes, allowing models to be converted between frameworks and optimized for execution providers like NVIDIA’s TensorRT. Caffe2 was merged into PyTorch at the end of March 2018. In September 2022, Meta announced that PyTorch would be governed by the independent PyTorch Foundation, a newly created subsidiary of the Linux Foundation. PyTorch 2.0 was released on 15 March 2023, introducing TorchDynamo, a Python-level compiler that makes code run up to two times faster, along with significant improvements in training and inference performance across major cloud platforms. == PyTorch tensors == PyTorch defines a class called Tensor (torch.Tensor) to store and operate on homogeneous multidimensional rectangular arrays of numbers. PyTorch supports various sub-types of multi-dimensional arrays, or Tensors. PyTorch Tensors are similar to NumPy Arrays, but can also be operated on by a CUDA-capable NVIDIA GPU. PyTorch has also been developing support for other GPU platforms, for example, AMD's ROCm and Apple's Metal Framework. == PyTorch neural networks == PyTorch defines a module called nn (torch.nn) to describe neural networks and to support training. This module offers a comprehensive collection of building blocks for neural networks, including various layers and activation functions, enabling the construction of complex models. Networks are built by inheriting from the torch.nn module and defining the sequence of operations in the forward() function. == PyTorch Serialized File Format == Pytorch can save and load models using its own file format, which is a ZIP64 archive containing the model weights in a Python pickle file, and other information such as the byte order. The file extensions .pt and .pth are commonly used for these files. == Example == The following program shows the low-level functionality of the library with a simple example. The following code block defines a neural network with linear layers using the nn module.
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AlphaGo

AlphaGo is a computer program that plays the board game Go. It was developed by the London-based DeepMind Technologies, an acquired subsidiary of Google. Subsequent versions of AlphaGo became increasingly powerful, including a version that competed under the name Master. After retiring from competitive play, AlphaGo Master was succeeded by an even more powerful version known as AlphaGo Zero, which was completely self-taught without learning from human games. AlphaGo Zero was then generalized into a program known as AlphaZero, which played additional games, including chess and shogi. AlphaZero has in turn been succeeded by a program known as MuZero which learns without being taught the rules. AlphaGo and its successors use a Monte Carlo tree search algorithm to find its moves based on knowledge previously acquired by machine learning, specifically by an artificial neural network (a deep learning method) by extensive training, both from human and computer play. A neural network is trained to identify the best moves and the winning percentages of these moves. This neural network improves the strength of the tree search, resulting in stronger move selection in the next iteration. In October 2015, in a match against Fan Hui, the original AlphaGo became the first computer Go program to beat a human professional Go player without handicap on a full-sized 19×19 board. In March 2016, it beat Lee Sedol in a five-game match, the first time a computer Go program has beaten a 9-dan professional without handicap. Although it lost to Lee Sedol in the fourth game, Lee resigned in the final game, giving a final score of 4 games to 1 in favour of AlphaGo. In recognition of the victory, AlphaGo was awarded an honorary 9-dan by the Korea Baduk Association. The lead up and the challenge match with Lee Sedol were documented in a documentary film also titled AlphaGo, directed by Greg Kohs. The win by AlphaGo was chosen by Science as one of the Breakthrough of the Year runners-up on 22 December 2016. At the 2017 Future of Go Summit, the Master version of AlphaGo beat Ke Jie, the number one ranked player in the world at the time, in a three-game match, after which AlphaGo was awarded professional 9-dan by the Chinese Weiqi Association. After the match between AlphaGo and Ke Jie, DeepMind retired AlphaGo, while continuing AI research in other areas. The self-taught AlphaGo Zero achieved a 100–0 victory against the early competitive version of AlphaGo, and its successor AlphaZero was perceived as the world's top player in Go by the end of the 2010s. == History == Go is considered much more difficult for computers to win than other games such as chess, because its strategic and aesthetic nature makes it hard to directly construct an evaluation function, and its much larger branching factor makes it prohibitively difficult to use traditional AI methods such as alpha–beta pruning, tree traversal and heuristic search. Almost two decades after IBM's computer Deep Blue beat world chess champion Garry Kasparov in the 1997 match, the strongest Go programs using artificial intelligence techniques only reached about amateur 5-dan level, and still could not beat a professional Go player without a handicap. In 2012, the software program Zen, running on a four PC cluster, beat Masaki Takemiya (9p) twice at five- and four-stone handicaps. In 2013, Crazy Stone beat Yoshio Ishida (9p) at a four-stone handicap. According to DeepMind's David Silver, the AlphaGo research project was formed around 2014 to test how well a neural network using deep learning can compete at Go. AlphaGo represents a significant improvement over previous Go programs. In 500 games against other available Go programs, including Crazy Stone and Zen, AlphaGo running on a single computer won all but one. In a similar matchup, AlphaGo running on multiple computers won all 500 games played against other Go programs, and 77% of games played against AlphaGo running on a single computer. The distributed version in October 2015 was using 1,202 CPUs and 176 GPUs. === Match against Fan Hui === In October 2015, the distributed version of AlphaGo defeated the European Go champion Fan Hui, a 2-dan (out of 9 dan possible) professional, five to zero. This was the first time a computer Go program had beaten a professional human player on a full-sized board without handicap. The announcement of the news was delayed until 27 January 2016 to coincide with the publication of a paper in the journal Nature describing the algorithms used. === Match against Lee Sedol === AlphaGo played South Korean professional Go player Lee Sedol, ranked 9-dan, one of the best players at Go, with five games taking place at the Four Seasons Hotel in Seoul, South Korea on 9, 10, 12, 13, and 15 March 2016, which were video-streamed live. Out of five games, AlphaGo won four games and Lee won the fourth game which made him recorded as the only human player who beat AlphaGo in all of its 74 official games. AlphaGo ran on Google's cloud computing with its servers located in the United States. The match used Chinese rules with a 7.5-point komi, and each side had two hours of thinking time plus three 60-second byoyomi periods. The version of AlphaGo playing against Lee used a similar amount of computing power as was used in the Fan Hui match. The Economist reported that it used 1,920 CPUs and 280 GPUs. At the time of play, Lee Sedol had the second-highest number of Go international championship victories in the world after South Korean player Lee Chang-ho who kept the world championship title for 16 years. Since there is no single official method of ranking in international Go, the rankings may vary among the sources. While he was ranked top sometimes, some sources ranked Lee Sedol as the fourth-best player in the world at the time. AlphaGo was not specifically trained to face Lee nor was designed to compete with any specific human players. The first three games were won by AlphaGo following resignations by Lee. However, Lee beat AlphaGo in the fourth game, winning by resignation at move 180. AlphaGo then continued to achieve a fourth win, winning the fifth game by resignation. The prize was US$1 million. Since AlphaGo won four out of five and thus the series, the prize will be donated to charities, including UNICEF. Lee Sedol received $150,000 for participating in all five games and an additional $20,000 for his win in Game 4. In June 2016, at a presentation held at a university in the Netherlands, Aja Huang, one of the Deep Mind team, revealed that they had patched the logical weakness that occurred during the 4th game of the match between AlphaGo and Lee, and that after move 78 (which was dubbed the "divine move" by many professionals), it would play as intended and maintain Black's advantage. Before move 78, AlphaGo was leading throughout the game, but Lee's move caused the program's computing powers to be diverted and confused. Huang explained that AlphaGo's policy network of finding the most accurate move order and continuation did not precisely guide AlphaGo to make the correct continuation after move 78, since its value network did not determine Lee's 78th move as being the most likely, and therefore when the move was made AlphaGo could not make the right adjustment to the logical continuation. === Sixty online games === On 29 December 2016, a new account on the Tygem server named "Magister" (shown as 'Magist' at the server's Chinese version) from South Korea began to play games with professional players. It changed its account name to "Master" on 30 December, then moved to the FoxGo server on 1 January 2017. On 4 January, DeepMind confirmed that the "Magister" and the "Master" were both played by an updated version of AlphaGo, called AlphaGo Master. As of 5 January 2017, AlphaGo Master's online record was 60 wins and 0 losses, including three victories over Go's top-ranked player, Ke Jie, who had been quietly briefed in advance that Master was a version of AlphaGo. After losing to Master, Gu Li offered a bounty of 100,000 yuan (US$14,400) to the first human player who could defeat Master. Master played at the pace of 10 games per day. Many quickly suspected it to be an AI player due to little or no resting between games. Its adversaries included many world champions such as Ke Jie, Park Jeong-hwan, Yuta Iyama, Tuo Jiaxi, Mi Yuting, Shi Yue, Chen Yaoye, Li Qincheng, Gu Li, Chang Hao, Tang Weixing, Fan Tingyu, Zhou Ruiyang, Jiang Weijie, Chou Chun-hsun, Kim Ji-seok, Kang Dong-yun, Park Yeong-hun, and Won Seong-jin; national champions or world championship runners-up such as Lian Xiao, Tan Xiao, Meng Tailing, Dang Yifei, Huang Yunsong, Yang Dingxin, Gu Zihao, Shin Jinseo, Cho Han-seung, and An Sungjoon. All 60 games except one were fast-paced games with three 20 or 30 seconds byo-yomi. Master offered to extend the byo-yomi to one minute when playing with Nie Weiping in consideration of his age. After winning its 59th game Master revealed itse
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Image-based modeling and rendering

In computer graphics and computer vision, image-based modeling and rendering (IBMR) methods rely on a set of two-dimensional images of a scene to generate a three-dimensional model and then render some novel views of this scene. The traditional approach of computer graphics has been used to create a geometric model in 3D and try to reproject it onto a two-dimensional image. Computer vision, conversely, is mostly focused on detecting, grouping, and extracting features (edges, faces, etc.) present in a given picture and then trying to interpret them as three-dimensional clues. Image-based modeling and rendering allows the use of multiple two-dimensional images in order to generate directly novel two-dimensional images, skipping the manual modeling stage. == Light modeling == Instead of considering only the physical model of a solid, IBMR methods usually focus more on light modeling. The fundamental concept behind IBMR is the plenoptic illumination function which is a parametrisation of the light field. The plenoptic function describes the light rays contained in a given volume. It can be represented with seven dimensions: a ray is defined by its position ( x , y , z ) {\displaystyle (x,y,z)} , its orientation ( θ , ϕ ) {\displaystyle (\theta ,\phi )} , its wavelength ( λ ) {\displaystyle (\lambda )} and its time ( t ) {\displaystyle (t)} : P ( x , y , z , θ , ϕ , λ , t ) {\displaystyle P(x,y,z,\theta ,\phi ,\lambda ,t)} . IBMR methods try to approximate the plenoptic function to render a novel set of two-dimensional images from another. Given the high dimensionality of this function, practical methods place constraints on the parameters in order to reduce this number (typically to 2 to 4). == IBMR methods and algorithms == View morphing generates a transition between images Panoramic imaging renders panoramas using image mosaics of individual still images Lumigraph relies on a dense sampling of a scene Space carving generates a 3D model based on a photo-consistency check
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DREAM Challenges

DREAM Challenges (Dialogue for Reverse Engineering Assessment and Methods) is a non-profit initiative for advancing biomedical and systems biology research via crowd-sourced competitions. Started in 2006, DREAM challenges collaborate with Sage Bionetworks to provide a platform for competitions run on the Synapse platform. Over 60 DREAM challenges have been conducted over the span of over 15 years. == Overview == DREAM Challenges were founded in 2006 by Gustavo Stolovizky from IBM Research and Andrea Califano from Columbia University. Current chair of the DREAM organization is Paul Boutros from University of California. Further organization spans emeritus chairs Justin Guinney and Gustavo Stolovizky, and multiple DREAM directors. Individual challenges focus on tackling a specific biomedical research question, typically narrowed down to a specific disease. A prominent disease focus has been on oncology, with multiple past challenges focused on breast cancer, acute myeloid leukemia, and prostate cancer or similar diseases. The data involved in an individual challenge reflects the disease context; while cancers typically involve data such as mutations in the human genome, gene expression and gene networks in transcriptomics, and large scale proteomics, newer challenges have shifted towards single cell sequencing technologies as well as emerging gut microbiome related research questions, thus reflecting trends in the wider research community. Motivation for DREAM Challenges is that via crowd-sourcing data to a larger audience via competitions, better models and insight is gained than if the analysis was conducted by a single entity. Past competitions have been published in such scientific venues as the flagship journals of the Nature Portfolio and PLOS publishing groups. Results of DREAM challenges are announced via web platforms, and the top performing participants are invited to present their results in the annual RECOMB/ISCB Conferences with RSG/DREAM organized by the ISCB. While DREAM Challenges have emphasized open science and data, in order to mitigate issues rising from highly sensitive data such as genomics in patient cohorts, "model to data" approaches have been adopted. In such challenges participants submit their models via containers such as Docker or Singularity. This allows retaining confidentiality of the original data as these containers are then run by the organizers on the confidential data. This differs from the more traditional open data model, where participants submit predictions directly based on the provided open data. == Challenge organization == DREAM challenge comprises a core DREAM/Sage Bionetworks organization group as well as an extended scientific expert group, who may have contributed to creation and conception of the challenge or by providing key data. Additionally, new DREAM challenges may be proposed by the wider research community. Pharmaceutical companies or other private entities may also be involved in DREAM challenges, for example in providing data. == Challenge structure == Timelines for key stages (such as introduction webinars, model submission deadlines, and final deadline for participation) are provided in advance. After the winners are announced, organizers start collaborating with the top performing participants to conduct post hoc analyses for a publication describing key findings from the competition. Challenges may be split into sub-challenges, each addressing a different subtopic within the research question. For example, regarding cancer treatment efficacy predictions, these may be separate predictions for progression-free survival, overall survival, best overall response according to RECIST, or exact time until event (progression or death). == Participation == During DREAM challenges, participants typically build models on provided data, and submit predictions or models that are then validated on held-out data by the organizers. While DREAM challenges avoid leaking validation data to participants, there are typically mid-challenge submission leaderboards available to assist participants in evaluating their performance on a sub-sampled or scrambled dataset. DREAM challenges are free for participants. During the open phase anybody can register via Synapse to participate either individually or as a team. A person may only register once and may not use any aliases. There are some exceptions, which disqualify an individual from participating, for example: Person has privileged access to the data for the particular challenge, thus providing them with an unfair advantage. Person has been caught or is under suspicion of cheating or abusing previous DREAM Challenges. Person is a minor (under age 18 or the age of majority in jurisdiction of residence). This may be alleviated via parental consent.
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RuleML

RuleML is a global initiative, led by a non-profit organization RuleML Inc., that is devoted to advancing research and industry standards design activities in the technical area of rules that are semantic and highly inter-operable. The standards design takes the form primarily of a markup language, also known as RuleML. The research activities include an annual research conference, the RuleML Symposium, also known as RuleML for short. Founded in fall 2000 by Harold Boley, Benjamin Grosof, and Said Tabet, RuleML was originally devoted purely to standards design, but then quickly branched out into the related activities of coordinating research and organizing an annual research conference starting in 2002. The M in RuleML is sometimes interpreted as standing for Markup and Modeling. The markup language was developed to express both forward (bottom-up) and backward (top-down) rules in XML for deduction, rewriting, and further inferential-transformational tasks. It is defined by the Rule Markup Initiative, an open network of individuals and groups from both industry and academia that was formed to develop a canonical Web language for rules using XML markup and transformations from and to other rule standards/systems. Markup standards and initiatives related to RuleML include: Rule Interchange Format (RIF): The design and overall purpose of W3C's Rule Interchange Format (RIF) industry standard is based primarily on the RuleML industry standards design. Like RuleML, RIF embraces a multiplicity of potentially useful rule dialects that nevertheless share common characteristics. RuleML Technical Committee from Oasis-Open: An industry standards effort devoted to legal automation utilizing RuleML. Semantic Web Rule Language (SWRL): An industry standards design, based primarily on an early version of RuleML, whose development was funded in part by the DARPA Agent Markup Language (DAML) research program. Semantic Web Services Framework, particularly its Semantic Web Services Language: An industry standards design, based primarily on a medium-mature version of RuleML, whose development was funded in part by the DARPA Agent Markup Language (DAML) research program and the WSMO research effort of the EU. Mathematical Markup Language (MathML): However, MathML's Content Markup is better suited for defining functions rather than relations or general rules Predictive Model Markup Language (PMML): With this XML-based language one can define and share various models for data-mining results, including association rules Attribute Grammars in XML (AG-markup): For AG's semantic rules, there are various possible XML markups that are similar to Horn-rule markup Extensible Stylesheet Language Transformations (XSLT): This is a restricted term-rewriting system of rules, written in XML, for transforming XML documents into other text documents
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Eline Van der Velden

Eline van der Velden is a Dutch comedian, writer, actress and producer based in London, England. She is best known for her work creating Tilly Norwood, an AI-generated "actress". == Early life == Van der Velden was born on the Dutch island of Curaçao, Netherlands Antilles to Dutch businessman Steven van der Velden and physiotherapist Quirine van der Velden. She moved to the United Kingdom at age 14 to study drama and musical theatre at Tring Park School for the Performing Arts. She graduated with an MSc in physics from Imperial College London in 2008. == Career == She was nominated by the International Academy of Digital Arts and Sciences for the Lovie Awards and won Best Online Comedy in 2013 for two of her submitted entries. She has created multiple online shows such as Sketch My Life with London Hughes and Emily Hartridge and Match.com Parody. She became managing director of Makers Channel (makerschannel.co.uk), the first curated video platform in Europe in 2015. Makers Channel has been recently acquired by a Belgian media company De Persgroep, due to its success in the Netherlands. In 2016, she appeared in adverts for the Dutch shampoo brand Andrelon. Miss Holland, a comedy character created by Van der Velden, made headlines in 2016 as she asked the British public to teach her the national anthem. As an actress, she has starred in Dutch TV series De Troon, Beatrix and the Golden Calf-winning series Overspel. In Belgium, she appeared opposite Jamie Dornan in Flying Home. Van der Velden starred in the BBC Three series Putting It Out There, in which she challenges social perceptions of body hair, heels, spit, personal space, and authority figures. In 2018, she starred in the BBC One comedy series Soft Border Patrol and the BBC Three comedy series Miss Holland. In 2025, Particle6 Group, which Van der Velden founded in 2016, introduced Tilly Norwood, an AI-generated "actress" at the Zurich Film Festival. The announcement was met with outrage and a condemnation by the American actors' union SAG-AFTRA. == Awards and recognition == Miss Holland won the Best Online Comedy at the 2013 Lovie Awards, judged by Stephen Fry. The Match.com Parody video won Best Online Comedy People's Lovie Award, the people's vote. Miss Holland and Match.com Parody Date 1 were also featured in the 2013 Google Lovie Letters.
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Vector database

A vector database, vector store or vector search engine is a database that stores and retrieves embeddings of data in vector space. Vector databases typically implement approximate nearest neighbor algorithms so users can search for records semantically similar to a given input, unlike traditional databases which primarily look up records by exact match. Use-cases for vector databases include similarity search, semantic search, multi-modal search, recommendations engines, object detection, and retrieval-augmented generation (RAG). Vector embeddings are mathematical representations of data in a high-dimensional space. In this space, each dimension corresponds to a feature of the data, with the number of dimensions ranging from a few hundred to tens of thousands, depending on the complexity of the data being represented. Each data item is represented by one vector in this space. Words, phrases, or entire documents, as well as images, audio, and other types of data, can all be vectorized. These feature vectors may be computed from the raw data using machine learning methods such as feature extraction algorithms, word embeddings or deep learning networks. The goal is that semantically similar data items receive feature vectors close to each other. Vector retrieval can be combined with metadata filtering or lexical search to support filtered and hybrid retrieval workflows. == Techniques == Common techniques for similarity search on high-dimensional vectors include: Hierarchical Navigable Small World (HNSW) graphs Locality-sensitive hashing (LSH) and sketching Product quantization (PQ) Inverted files These techniques may also be combined in vector search systems. In recent benchmarks, HNSW-based implementations have been among the best performers. Conferences such as the International Conference on Similarity Search and Applications (SISAP) and the Conference on Neural Information Processing Systems (NeurIPS) have hosted competitions on vector search in large databases. == Applications == Vector databases are used in a wide range of machine learning applications including similarity search, semantic search, multi-modal search, recommendations engines, object detection, and retrieval-augmented generation. === Retrieval-augmented generation === An especially common use-case for vector databases is in retrieval-augmented generation (RAG), a method to improve domain-specific responses of large language models. The retrieval component of a RAG can be any search system, but is most often implemented as a vector database. Text documents describing the domain of interest are collected, and for each document or document section, a feature vector (known as an "embedding") is computed, typically using a deep learning network, and stored in a vector database along with a link to the document. Given a user prompt, the feature vector of the prompt is computed, and the database is queried to retrieve the most relevant documents. These are then automatically added into the context window of the large language model, and the large language model proceeds to create a response to the prompt given this context. == Implementations ==
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CuckooChess

CuckooChess is an advanced free and open-source chess engine under the GNU General Public License written in Java by Peter Österlund. CuckooChess provides an own GUI, and optionally supports the Universal Chess Interface protocol for the use with external GUIs such as Arena. An Android port is available, where its GUI is also based on Peter Österlund's Stockfish port dubbed DroidFish. The program uses the Chess Cases chess font, created by Matthieu Leschemelle. The name CuckooChess comes due that the transposition table is based on Cuckoo hashing. Android app based chess gaming app Droidfish employs both CuckooChess and Stockfish chess engines. Similarly, Kickstarter funded AI based virtual reality chess game Square Off also uses CuckooChess engine. It has an ELO rating of 2583 (as of July 2018) and a rank of 135‑137 in the Computer Chess Rating List.
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Comet (browser)

Comet is an AI-powered web browser based on Chromium. It was released by Perplexity AI for Microsoft Windows and macOS on July 9, 2025, for Android on November 20, 2025, and for iOS on March 18, 2026. Initial access to the browser was limited to users subscribed to Perplexity's most expensive tier, with broader availability expected over time. The browser was released for free download in October 2025. == Features == Comet is integrated with Perplexity's AI-assisted search engine. The browser features an assistant which enables users to perform a variety of tasks such as generating article summaries, sending emails, or buying products. == Security concerns == Researchers at LayerX Security identified a malicious attack vector which they call CometJacking. The exploit could possibly exfiltrate a user's personal sensitive data to a remote server controlled by the attacker. LayerX attempted to responsibly disclose their findings to Comet's developer Perplexity AI in August 2025. Perplexity responded that they saw no security impact and marked the disclosure as not applicable.
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