AI Chatbot Ux

AI Chatbot Ux — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

Lost Art-Database

The Lost Art-Datenbank is an online database published by the German Lost Art Foundation (Deutsches Zentrum Kulturgutverluste. It contains information on cultural objects looted from Jewish collectors or transferred due to Nazi persecution during the Nazi era. Until 2015, it was managed by the Koordinierungsstelle für Kulturgutverluste (Magdeburg Coordination Office). == Creation == Following the Washington Conference of 1998, and the commitments to provide more transparency regarding looted art, Germany launched the Lost Art Database in 2000 order to help Holocaust victims and their families track down artworks that had been looted from them or lost due to Nazi persecution. == Functionality == The Lost Art Database lists art and books and other cultural objects that were lost, seized, stolen or forceably sold during the Nazi era. The database is divided into search requests from victims' families, heirs or institutions and "found" reports from cultural institutions on items with unresolved provenance gaps from the Nazi periods. The section on reports of finds lists objects that are known to have been unlawfully seized or relocated as a result of the war. In addition, reports are published here on cultural objects for which an uncertain or incomplete provenance may indicate a possible unlawful seizure or war-related relocation. The publication of reports in the Lost Art Internet Database is carried out on behalf of and with the consent of the reporting persons and institutions. The responsibility for the content of the reports lies with these legal or natural persons. There have been controversies over which items should be included in the database. Lost Art is based on the Washington Principles adopted in 1998, which Germany has committed itself to implementing (Joint Declaration, 1999). The Lost Art Database is considered a key resource in the search for looted art and the victims of persecution. Every item in the Lost Art Database has an identifier, known as a Lost Art ID. Proveana is the linked research database. == Other lost art databases == Other countries have launched databases to help identify Nazi looted art. Each database has its own area of focus. The German Lost Art Database allows families or heirs to submit information. Other countries have databases that focus on looted artworks that have not been found or artworks that were repatriated to the national authorities after the defeat of the Nazis but were never returned to their original owners. Other databases have been created for stolen antiquities, looted art from colonial era, art stolen from Syria, Iraq, Ukraine, or from museums or collectors.
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Project Mariner

Project Mariner was a research prototype developed by Google DeepMind that explored human-agent interactions, particularly within web browsers. It automated tasks such as online shopping, information retrieval, and form-filling, aiming to enhance user productivity by delegating routine web-based tasks to an AI agent. Project Mariner operated as an experimental Chrome extension that understands the contents of your screen, including images, code, forms, and more. It could interpret complex goals, plan actionable steps, and navigate websites to carry out tasks, while keeping the user informed and allowing them to intervene at any time. As of May 2025, Project Mariner was available to Google AI Ultra subscribers in the US and was being integrated into the Gemini API and Vertex AI, allowing developers to build applications powered by the agent Google plans to bring Project Mariner’s capabilities to more countries and integrate it into Google Search's AI Mode, which was currently in the Search Labs testing phase. Project Mariner was discontinued on May 4, 2026.
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Drools

Drools is a business rule management system (BRMS) with a forward and backward chaining inference-based rules engine, more correctly known as a production rule system, using an enhanced implementation of the Rete algorithm. Drools supports the Java Rules Engine API (Java Specification Request 94) standard for its business rule engine and enterprise framework for the construction, maintenance, and enforcement of business policies in an organization, application, or service. == Drools in Apache Kie == Drools, as part of the Kie Community has entered Apache Incubator in January, 2023. == Red Hat Decision Manager == Red Hat Decision Manager (formerly Red Hat JBoss BRMS) is a business rule management system and reasoning engine for business policy and rules development, access, and change management. JBoss Enterprise BRMS is a productized version of Drools with enterprise-level support available. JBoss Rules is also a productized version of Drools, but JBoss Enterprise BRMS is the flagship product. Components of the enterprise version: JBoss Enterprise Web Platform – the software infrastructure, supported to run the BRMS components only JBoss Enterprise Application Platform or JBoss Enterprise SOA Platform – the software infrastructure, supported to run the BRMS components only Business Rules Engine – Drools Expert using the Rete algorithm and the Drools Rule Language (DRL) Business Rules Manager – Drools Guvnor - Guvnor is a centralized repository for Drools Knowledge Bases, with rich web-based GUIs, editors, and tools to aid in the management of large numbers of rules. Business Rules Repository – Drools Guvnor Drools and Guvnor are JBoss Community open source projects. As they are mature, they are brought into the enterprise-ready product JBoss Enterprise BRMS. Components of the JBoss Community version: Drools Guvnor (Business Rules Manager) – a centralized repository for Drools Knowledge Bases Drools Expert (rule engine) – uses the rules to perform reasoning Drools Flow (process/workflow), or jBPM 5 – provides for workflow and business processes Drools Fusion (event processing/temporal reasoning) – provides for complex event processing Drools Planner/OptaPlanner (automated planning) – optimizes automated planning, including NP-hard planning problems == Example == This example illustrates a simple rule to print out information about a holiday in July. It checks a condition on an instance of the Holiday class, and executes Java code if that condition is true. The purpose of dialect "mvel" is to point the getter and setters of the variables of your Plain Old Java Object (POJO) classes. Consider the above example, in which a Holiday class is used and inside the circular brackets (parentheses) "month" is used. So with the help of dialect "mvel" the getter and setters of the variable "month" can be accessed. Dialect "java" is used to help us write our Java code in our rules. There is one restriction or characteristic on this. We cannot use Java code inside the "when" part of the rule but we can use Java code in the "then" part. We can also declare a Reference variable $h1 without the $ symbol. There is no restriction on this. The main purpose of putting the $ symbol before the variable is to mark the difference between variables of POJO classes and Rules.
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Sriram Krishnan

Sriram Krishnan (born 1984) is a tech executive and White House official, currently serving as the Senior White House Policy Advisor on Artificial Intelligence. Krishnan was named a Time Person of the Year in 2025 as an "Architect of Artificial Intelligence." He was described in Time as providing the "wake-up call that we needed" to the other AI builders, leading to "a multiyear, $500 billion initiative dubbed Stargate" to push American-made AI, as well as numerous other AI initiatives. Also in December 2025, President Trump said of Krishnan, "without him, things on AI would not function well" and cited Krishnan as the leading figure behind the American executive order on AI. As the leader of the United States' policy team regarding artificial intelligence, Krishnan plays "a significant role in shaping the administration’s approach to AI and driving measures to advance federal adoption of AI." The role calls for removing barriers to AI adoption within the government, driving vendors toward solutions suitable for federal needs, designing sensible regulation of private-sector AI, and conducting "AI diplomacy". He has stated a policy goal of "reinvigorating US dominance in emerging technologies," including AI. He also represents the United States' interests in AI abroad, such as at the Paris AI Summit. He is one of the authors of the American "AI Action Plan" released in July, 2025, which he contends is necessary to win the "existential race with China" for AI supremacy. Krishnan, a U.S. citizen born in India, is also a venture capitalist, podcaster, product manager and author. Early in his career, he led product teams at Microsoft, Twitter, Yahoo!, Facebook, and Snap. In addition to his work as an investor and technologist, he and his wife, Aarthi Ramamurthy, rose to additional prominence in 2021 as podcast hosts. He served as a general partner at the venture capital firm Andreessen Horowitz and led its London office. In 2022, Krishnan announced that he was working with Elon Musk on the rebuilding of Twitter following Musk's acquisition of the company. On December 22, 2024, US president-elect Donald Trump announced that Krishnan would be Senior White House Policy Advisor on Artificial Intelligence in his incoming administration; in 2026 he joined the National Economic Council. == Early life and education == Krishnan was born in Chennai, India. He earned his Bachelor of Technology in Information Technology from SRM University (2001–2005), moved to the United States in 2007 to join Microsoft, and became a naturalized U.S. citizen in 2016. == Career == === Early career === In 2007, he began working at Microsoft where he served as a program manager for Visual Studio. At Facebook, Krishnan built the Facebook Audience Network, a competitive platform to Google's ad technologies. At Twitter, he led product and core user experience, driving a 20% annual user growth rate and launching a redesigned home page and events experience. === Andreessen Horowitz === Krishnan was appointed a general partner of American venture capital firm Andreessen Horowitz ("a16z") in February 2021. He was anticipated to serve consumer and social markets, however he has also theorized on the impact of "deep tech" on society. In 2023 he was appointed to lead the firm's London office, its first non-US location. The office is expected to serve Web3 investments as well as AI and other fields. Krishnan announced that he would leave the firm at the end of 2024. === Social media and AI === In 2022, various news media reported that Krishnan was assisting Elon Musk in the revamp of Twitter following Musk's takeover of the company. Additional reports named Krishnan as the leading candidate for the role of CEO of the newly private company. Krishnan penned a 2023 New York Times opinion column regarding social media, AI, and related fields. He predicted a rise in the number and diversity of online spaces due to decentralization and platforms like Farcaster, Bluesky and Mastodon. === Public office === In 2024, the Financial Times reported that Krishnan was active in international affairs, reintroducing Boris Johnson to Elon Musk, following Musk's nomination to the proposed Department of Government Efficiency. Krishnan was also reported as potentially leaving a16z at the end of the year to "be jumping into something I've wanted to spend [his] energy on," which was widely reported as being related to Musk's and Vivek Ramaswamy's work at DOGE. Others reported to be involved include Joe Lonsdale, Marc Andreesen, Bill Ackman, and Travis Kalanick. On December 22, 2024, US president-elect Donald Trump announced that he would be Senior White House Policy Advisor on Artificial Intelligence in his incoming administration. On February 6, 2025, Reuters reported that Krishnan would be accompanying Vice President Vance to the Paris AI Summit, a "major artificial intelligence" event later that month. Other members of the White House Office of Science and Technology Policy would also be joining the event with around 100 other countries to "focus on AI's potential." Krishnan joined a U.S. technology policy delegation to the Middle East in advance of President Trump's visit in May 2025. Conducting "AI diplomacy," Krishnan negotiated the spread of U.S. AI technologies with Crown Prince Mohammed bin Salman of Saudi Arabia, as well as other means to strengthen bilateral trade in artificial intelligence technologies. He explained that the goal of the diplomatic mission was that "we want American A.I. to spread." Krishnan, along with David Sacks and Michael Kratsios, were credited as authors of the American AI Action Plan released in July 2025. The plan is "the administration’s most significant policy directive" regarding artificial intelligence; it calls for financing to support the global spread of American AI models and a policy to enforce neutrality in models. The Washington Post referred to the plan as a "bold action to ensure that American AI remains at the cutting edge." The AI Action Plan is a continuation of prior efforts to reduce barriers to U.S. production of AI systems and the removal of rules that were considered to hinder such growth. Later in 2025, at the POLITICO AI & Tech Summit, Krishnan called national AI development "an existential race with China." He suggested that private companies are best positioned to create new models, quipping "let them cook." He further suggested that state-by-state regulation of AI technologies may hinder national AI competitiveness. Also in 2025, at the Axios AI+ Summit, Krishnan stated that the United States and China are in a race for AI supremacy, in which the winner will be judged by market share. Winning the race is a "business strategy" to Krishnan. Krishnan was named in the 2025 Time Person of the Year article as an "AI Architect". === The Aarthi and Sriram Show and other media === In early 2021, Krishnan and his wife, Aarthi Ramamurthy, launched a Clubhouse talk show that "focuses on organic conversations on anything from startups to venture capitalism and cryptocurrencies." An early appearance by Elon Musk on the Good Time Show was described as the first show that "broke Clubhouse" by rapidly exceeding the limit of 5,000 simultaneous users. The desire to interact with a larger community led to a variety of later innovations to allow streaming and replaying of Clubhouse chats. On that episode, Elon Musk grilled Robinhood CEO Vlad Tenev regarding the GameStop trading controversy. As of December 2021, the show had over 187,000 subscribers, plus 735,000 subscribers between Krishnan and Ramamurthy's personal Clubhouse accounts. Other guests have included Facebook CEO Mark Zuckerberg, Diane von Fürstenberg, Tony Hawk, MrBeast, and A.R. Rahman. In 2022, the Good Time Show moved to YouTube. It then evolved to a podcasting format under the name The Aarthi and Sriram Show, with both audio and video content. The Hollywood Reporter reported that the podcast had received more than 1 million downloads by early 2023. == Personal life == Krishnan is married to Aarthi Ramamurthy, co-host of The Aarthi and Sriram Show (formerly the Good Time Show) and a serial entrepreneur. They met in college in 2003 through a Yahoo! chat room related to a coding project and began dating in 2006 and eloped in 2010. == Awards == Time Person of the Year - 2025
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Sketchpad

Sketchpad (a.k.a. Robot Draftsman) is a computer program written by Ivan Sutherland in 1963 in the course of his PhD thesis, for which he received the Turing Award in 1988, and the Kyoto Prize in 2012. It pioneered human–computer interaction (HCI), and is considered the ancestor of modern computer-aided design (CAD) programs and as a major breakthrough in the development of computer graphics in general. For example, Sketchpad inspired the graphical user interface (GUI) and object-oriented programming. Using the program, Sutherland showed that computer graphics could be used for both artistic and technical purposes and for demonstrating a novel method of human–computer interaction. == History == See History of the graphical user interface for a more detailed discussion of GUI development. == Software == Sketchpad was the earliest program ever to use a complete graphical user interface. The clever way the program organizes its geometric data pioneered the use of master (objects) and occurrences (instances) in computing and pointed forward to object-oriented programming. The main idea was to have master drawings which can be instantiated into many duplicates. When a master drawing is changed, then all instances change also. This was the first known form of an entity component system: for example instead of encapsulating points inside of a line object, the points are stored in a ring buffer as described in pages 48 to 52 of the paper, and the line only points to them. This allowed moving one point to alter all the shapes that use it in a single operation. The structures in Sketchpad were also able to store pointers to functions, to achieve a different behavior depending on the kind of object. In figure 3.8 of the paper, the "instances generic block" stores several "subroutine entries" which are pointers to functions: "display", "howbig" etc. This was an early form of virtual functions. Geometric constraints was another major invention in Sketchpad, letting a user easily constrain geometric properties in the drawing: for instance, the length of a line or the angle between two lines could be fixed. As a trade magazine said, clearly Sutherland "broke new ground in 3D computer modeling and visual simulation, the basis for computer graphics and CAD/CAM". Very few programs can be called precedents for his achievements. Patrick J. Hanratty is sometimes called the "father of CAD/CAM" and wrote PRONTO, a numerical control language at General Electric in 1957, and wrote CAD software while working for General Motors beginning in 1961. Sutherland wrote in his thesis that Bolt, Beranek and Newman had a "similar program" and T-Square was developed by Peter Samson and one or more fellow MIT students in 1962, both for the PDP-1. The Computer History Museum holds program listings for Sketchpad. == Hardware == Sketchpad ran on the MIT Lincoln Laboratory TX-2 (1958) computer at the Massachusetts Institute of Technology (MIT), which had 64k of 36-bit words. The user drew on the computer monitor screen with the recently invented light pen, which relayed information on its position by computing at what time the light from the scanning cathode-ray tube screen is detected. To configure the initial position of the light pen, the word INK was displayed on the screen, which, upon tapping, initialised the program with a white cross to continue keeping track of the pen's movement relative to its prior position. Of the 36 bits available to store each display spot in the display file, 20 gave the coordinates of that spot for the display system and the remaining 16 gave the address of the n-component element responsible for adding that spot to display. The TX-2 was an experimental machine and the hardware changed often (on Wednesdays, according to Sutherland). By 1975, the light pen and the cathode-ray tube with which it had been used had been removed. == Publications == The Sketchpad program was part and parcel of Sutherland's Ph.D. thesis at MIT and peripherally related to the Computer-Aided Design project at that time. Sketchpad: A Man-Machine Graphical Communication System.
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Aidan Gomez

Aidan Gomez is a British-Canadian computer scientist working in the field of artificial intelligence, with a focus on natural language processing. He is the co-founder and CEO of the technology company Cohere. == Early life and education == Gomez grew up in Brighton, Ontario. He graduated from the University of Toronto with a bachelor's degree in computer science and mathematics. He was pursuing a PhD in computer science from the University of Oxford. He paused his studies to launch Cohere. He was granted the PhD in 2024. == Career == In 2017, as a 20 year-old intern at Google Brain, Gomez was one of eight authors of the research paper "Attention Is All You Need", which is credited with changing the AI industry and helping lead to the creation of ChatGPT. The paper proposed a novel deep learning architecture called the transformer, that enables machine learning models to analyze large amounts of data for patterns, and then use those patterns to make predictions while leveraging GPU parallelization. It has been commonly adopted for training large language models and in the development of generative AI. In the same year, Gomez founded FOR.ai, a program to help researchers learn machine learning techniques in a collaborative format. An outgrowth of this project was Cohere For AI (now Cohere Labs), which released Aya, an open-source multilingual LLM. As a PhD student, Gomez worked as a machine learning researcher at Google Brain. At that time, he co-authored the paper "One Model to Learn Them All" about multi-task learning by a single neural network. In 2019, Gomez left Google Brain to launch Cohere, an enterprise-focused company that helps businesses implement AI into chatbots, search engines, and other products. As of Sept 2025, Cohere has raised about US$1.6 billion at valuation north of $7 billion, as Gomez leads the company as its CEO. Gomez was named to the 2023 Time 100/AI list of the most influential people in the field of artificial intelligence. He and his fellow Cohere founders Ivan Zhang and Nick Frosst were named number 1 on 2023 Maclean's AI Trailblazers Power List. In April 2025, Gomez was elected to the board of Rivian. == Views on AI == Gomez has stated that warnings regarding the existential risk from artificial intelligence are overblown, and that real risks involve the automated spread of misinformation on social media. He said that the United States would win the AI arms race over China.
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Decision Model and Notation

In business analysis, the Decision Model and Notation (DMN) is a standard published by the Object Management Group. It is a standard approach for describing and modeling repeatable decisions within organizations to ensure that decision models are interchangeable across organizations. The DMN standard provides the industry with a modeling notation for decisions that will support decision management and business rules. The notation is designed to be readable by business and IT users alike. This enables various groups to effectively collaborate in defining a decision model: the business people who manage and monitor the decisions, the business analysts or functional analysts who document the initial decision requirements and specify the detailed decision models and decision logic, the technical developers responsible for the automation of systems that make the decisions. The primary goal of DMN is to offer a common notation that all business users can easily understand. This includes business analysts who develop decision requirements and models, technical developers who automate decisions, and businesspeople who manage and monitor those decisions. DMN serves as a standardized link between business decision design and implementation.[4] The DMN standard can be effectively used standalone but it is also complementary to the BPMN and CMMN standards. BPMN defines a special kind of activity, the Business Rule Task, which "provides a mechanism for the process to provide input to a business rule engine and to get the output of calculations that the business rule engine might provide" that can be used to show where in a BPMN process a decision defined using DMN should be used. DMN has been made a standard for Business Analysis according to BABOK v3. == Elements of the standard == The standard includes three main elements Decision Requirements Diagrams that show how the elements of decision-making are linked into a dependency network. Decision tables to represent how each decision in such a network can be made. Business context for decisions such as the roles of organizations or the impact on performance metrics. A Friendly Enough Expression Language (FEEL) that can be used to evaluate expressions in a decision table and other logic formats. == Use cases == The standard identifies three main use cases for DMN Defining manual decision making Specifying the requirements for automated decision-making Representing a complete, executable model of decision-making == Benefits == Using the DMN standard will improve business analysis and business process management, since other popular requirement management techniques such as BPMN and UML do not handle decision making growth of projects using business rule management systems or BRMS, which allow faster changes it facilitates better communications between business, IT and analytic roles in a company it provides an effective requirements modeling approach for predictive analytics projects and fulfills the need for "business understanding" in methodologies for advanced analytics such as CRISP-DM it provides a standard notation for decision tables, the most common style of business rules in a business rule management system (BRMS) == Relationship to BPMN == DMN has been designed to work with BPMN. Business process models can be simplified by moving process logic into decision services. DMN is a separate domain within the OMG that provides an explicit way to connect to processes in BPMN. Decisions in DMN can be explicitly linked to processes and tasks that use the decisions. This integration of DMN and BPMN has been studied extensively. DMN expects that the logic of a decision will be deployed as a stateless, side-effect free Decision Service. Such a service can be invoked from a business process and the data in the process can be mapped to the inputs and outputs of the decision service. == DMN BPMN example == As mentioned, BPMN is a related OMG Standard for process modeling. DMN complements BPMN, providing a separation of concerns between the decision and the process. The example here describes a BPMN process and DMN DRD (Decision Requirements Diagram) for onboarding a bank customer. Several decisions are modeled and these decisions will direct the processes response. === New bank account process === In the BPMN process model shown in the figure, a customer makes a request to open a new bank account. The account application provides the account representative with all the information needed to create an account and provide the requested services. This includes the name, address and various forms of identification. In the next steps of the work flow, the know your customer (KYC) services are called. In the KYC services, the name and address are validated; followed by a check against the international criminal database (Interpol) and the database of persons that are 'politically exposed persons (PEP)'. The PEP is a person who is either entrusted with a prominent political position or a close relative thereof. Deposits from persons on the PEP list are potentially corrupt. This is shown as two services on the process model. Anti-money-laundering (AML) regulations require these checks before the customer account is certified. The results of these services plus the forms of identification are sent to the Certify New Account decision. This is shown as a 'rule' activity, verify account, on the process diagram. If the new customer passes certification, then the account is classified into onboarding for business retail, retail, wealth management and high-value business. Otherwise the customer application is declined. The Classify New Customer Decision classifies the customer. If the verify-account process returns a result of 'Manual' then the PEP or the Interpol check returned a close match. The account representative must visually inspect the name and the application to determine if the match is valid and accept or decline the application. === Certify new account decision === An account is certified for opening if the individual's' address is verified, and if valid identification is provided, and if the applicant is not on a list of criminals or politically exposed persons. These are shown as sub-decisions below the 'certify new account' decision. The account verification services provides a 100% match of the applicants address. For identification to be valid, the customer must provide a driver's license, passport or government issued ID. The checks against PEP and Interpol are 'fuzzy' matches and return matching score values. Scores above 85 are considered a 'match' and scores between 65 and 85 would require a 'manual' screening process. People who match either of these lists are rejected by the account application process. If there is a partial match with a score between 65 and 85, against the Interpol or PEP list then the certification is set to manual and an account representative performs a manual verification of the applicant's data. These rules are reflected in the figure below, which presents the decision table for whether to pass the provided name for the lists checks. === Client category === The client's on-boarding process is driven by what category they fall in. The category is decided by the: Type of client, business or private The size of the funds on deposit And the estimated net worth This decision is shown below: There are 6 business rules that determine the client's category and these are shown in the decision table here: === Summary example === In this example, the outcome of the 'Verify Account' decision directed the responses of the new account process. The same is true for the 'Classify Customer' decision. By adding or changing the business rules in the tables, one can easily change the criteria for these decisions and control the process differently. Modeling is a critical aspect of improving an existing process or business challenge. Modeling is generally done by a team of business analysts, IT personnel, and modeling experts. The expressive modeling capabilities of BPMN allows business analyst to understand the functions of the activities of the process. Now with the addition of DMN, business analysts can construct an understandable model of complex decisions. Combining BPMN and DMN yields a very powerful combination of models that work synergistically to simplify processes. == Relationship to decision mining and process mining == Automated discovery techniques that infer decision models from process execution data have been proposed as well. Here, a DMN decision model is derived from a data-enriched event log, along with the process that uses the decisions. In doing so, decision mining complements process mining with traditional data mining approaches. == cDMN extension == Constraint Decision Model and Notation (cDMN) is a formal notation for expressing knowledge in a tabular, intuitive format. It extends DMN with constraint reasoning and related concepts while aiming to retain the us
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Clinical quality management system

Clinical quality management systems (CQMS) are systems used in the life sciences sector (primarily in the pharmaceutical, biologics and medical device industries) designed to manage quality management best practices throughout clinical research and clinical study management. A CQMS system is designed to manage all of the documents, activities, tasks, processes, quality events, relationships, audits and training that must be administered and controlled throughout the life of a clinical trial. The premise of a CQMS is to bring together the activities led by two sectors of clinical research, Clinical Quality and Clinical Operations, to facilitate cross-functional activities to improve efficiencies and transparency and to encourage the use of risk mitigation and risk management practices at the clinical study level. Based on the principles of quality management systems (QMS) which are used in many industries to create a framework for defining and delivering quality outcomes, managing risk, and continual improvement. Many guidelines and governance bodies have been established to ensure a common approach within a given industry to a set of parameters used to identify the minimally acceptable standard for that industry. The pharmaceutical industry is no exception, with several trade groups (e.g. PhRMA, EFPIA, RQA, etc.) coming together to enhance collaboration. However, as noted by the Academy of Medical Sciences, there are increasingly complex and bureaucratic legal and ethical frameworks that innovators must work within to develop new medicines for patients. The historical pharmaceutical QMS applies primarily to good manufacturing practice as described in existing ISO (International Organization for Standardization) and ICH (International Committee on Harmonization) guidelines. "Good Manufacturing Practices (GMP) relate to quality control and quality assurance enabling companies in the pharmaceutical sector to minimize or eliminate instances of contamination, mix-ups, and errors. This in turn, protects the customer from purchasing a product which is ineffective or even dangerous." These standards have historically been applied to the manufacturing environment, appropriate to how they have been written. However, according to FDA as well as other regulatory bodies, "Implementation of ICH Q10 throughout the product lifecycle should facilitate innovation and continual improvement", implying that the same standards that apply to the manufacturing environment should also be applied to the clinical research space, earlier in the lifecycle of an investigational or marketed product. Accordingly, a CQMS is any system developed to apply these principles to clinical operations within an organization.
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VGACAD

VGACAD was the parent of a suite of shareware graphic utilities made for the MS-DOS operating system used in the IBM PC and clones. It was popular for editing and capturing images using BSAVE (graphics image format) and provided an early graphic editing suite compatible with multiple graphic cards and resolutions, used on the IBM PC. == Usage == Written by Lawrence Gozum in 1987, it was the genesis of multiple versions and improvements over 10 years. Ran with his brother, Marvin initially helped with design ideas, strategic focus, technical support calls, and managing the early shareware business. The growth of the VGACAD suite grew quickly to preoccupy most of their time. Lawrence then focused more of his efforts on software and formed Applied Insights, to manage VGACAD and its offspring, VidFun, and Ai Picture Explorer. At its peak, its users ranged from individuals, Federal government offices, museums and major newspapers. == Features == VGACAD was a misnomer, and meant VGA-Computer Assisted Drawing, rather than computer-aided design, as CAD is commonly referred to today. Its longevity was due to its color accuracy, speed, small size, and that its suite of small utilities often worked stand-alone. One called VGACAP, for 'capture', dumped video memory into a file that could later be converted to popular graphic image formats, later made commonplace when Microsoft Windows programmed the print screen key to dump graphics into the clipboard. However, VGACAP ran insulated apart from early versions of Windows, and thus could capture screens were applications prohibited such function.
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Aidan Gomez

Aidan Gomez is a British-Canadian computer scientist working in the field of artificial intelligence, with a focus on natural language processing. He is the co-founder and CEO of the technology company Cohere. == Early life and education == Gomez grew up in Brighton, Ontario. He graduated from the University of Toronto with a bachelor's degree in computer science and mathematics. He was pursuing a PhD in computer science from the University of Oxford. He paused his studies to launch Cohere. He was granted the PhD in 2024. == Career == In 2017, as a 20 year-old intern at Google Brain, Gomez was one of eight authors of the research paper "Attention Is All You Need", which is credited with changing the AI industry and helping lead to the creation of ChatGPT. The paper proposed a novel deep learning architecture called the transformer, that enables machine learning models to analyze large amounts of data for patterns, and then use those patterns to make predictions while leveraging GPU parallelization. It has been commonly adopted for training large language models and in the development of generative AI. In the same year, Gomez founded FOR.ai, a program to help researchers learn machine learning techniques in a collaborative format. An outgrowth of this project was Cohere For AI (now Cohere Labs), which released Aya, an open-source multilingual LLM. As a PhD student, Gomez worked as a machine learning researcher at Google Brain. At that time, he co-authored the paper "One Model to Learn Them All" about multi-task learning by a single neural network. In 2019, Gomez left Google Brain to launch Cohere, an enterprise-focused company that helps businesses implement AI into chatbots, search engines, and other products. As of Sept 2025, Cohere has raised about US$1.6 billion at valuation north of $7 billion, as Gomez leads the company as its CEO. Gomez was named to the 2023 Time 100/AI list of the most influential people in the field of artificial intelligence. He and his fellow Cohere founders Ivan Zhang and Nick Frosst were named number 1 on 2023 Maclean's AI Trailblazers Power List. In April 2025, Gomez was elected to the board of Rivian. == Views on AI == Gomez has stated that warnings regarding the existential risk from artificial intelligence are overblown, and that real risks involve the automated spread of misinformation on social media. He said that the United States would win the AI arms race over China.
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Danilo McGarry

Danilo McGarry (born 1985) is a British tech executive, writer, and speaker who has led AI initiatives in finance and healthcare. == Early life and education == Danilo McGarry was born in 1985. He received a Bachelor of Science (BSc) with honors in Business Management from the University of Bath. == Career == McGarry began his career in technology and financial services, with positions at companies including Motorola, JPMorgan Chase, and BNP Paribas. He later joined the Royal Bank of Canada (RBC) as an analyst and later became a director, where he led transformation initiatives involving robotic process automation (RPA) in the bank's capital markets operations. McGarry subsequently moved into leadership roles focused on AI. At Citigroup, he served as Head of Artificial Intelligence and Machine Learning, where he launched an AI-driven robotics and automation initiative. At UnitedHealth Group (UHG), he held a senior role in the company's automation program, which utilized a large fleet of software robots in its healthcare operations. In December 2019, McGarry was appointed Global Head of AI & Automation at Alter Domus, a multinational financial services firm. In this role, he established a new AI and automation department. He left the firm in late 2023 to establish his businesses. In 2025, the Chartered Institute of Personnel and Development (CIPD) appointed him as its strategic adviser on artificial intelligence.
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Lukas Biewald

Lukas Biewald (born 1981) is an American entrepreneur and a prominent figure in artificial intelligence. He is recognized for his contributions to machine learning and as the CEO and co-founder of Weights & Biases, a company that builds developer tools for AI, that sold to CoreWeave in 2025 for $1.7B. He previously founded and was CEO of Figure Eight, a human-in-the-loop machine learning platform. He has co-authored 26 AI research papers from 2004 through 2018. == Early life and education == Biewald was born in Boston, Massachusetts in 1981. He attended Cambridge Rindge and Latin School and later earned both a Bachelor's and Master's degree in Computer science from Stanford University. == Early Career and Founding Figure Eight == After graduation, Biewald joined Yahoo! as an engineer, working on machine translations to improve search results, and eventually led the Search Relevance Team for Yahoo! Japan. He later joined Powerset, a natural language search technology company, as their Senior Scientist, which was acquired by Microsoft in 2008 for an estimated $100M. In 2007, Biewald co-founded Figure Eight (formerly CrowdFlower), a data labeling and crowdsourcing company that created datasets for training machine learning models. Figure Eight was acquired by Appen in 2019 for $300 million. == Weights and Biases == In 2017, Biewald co-founded Weights & Biases with Chris Van Pelt and Shawn Lewis. The company provides tools for tracking machine learning experiments, model management, and collaborative AI and LLM app development. The platform has been adopted by organizations such as OpenAI, Salesforce, and Microsoft. In March 2025 Coreweave acquired Weights and Biases at $1.7 billion, with the transaction closing on May 5, 2025. == Gradient Dissent == Biewald hosts the bi-weekly podcast Gradient Dissent. Guest have included: Anthony Goldbloom – Co-founder & CEO of Kaggle. “How to Win Kaggle Competitions” (podcast, Sep. 9, 2020). Shared tips on data-science competitions from the founder of the largest ML community. Richard Socher – Founder & CEO of You.com; former Chief Scientist at Salesforce. “The Challenges of Making ML Work in the Real World” (podcast, September 28, 2020). A leading NLP researcher, he spoke on multimodal search engines powered by large language models. Jensen Huang – Founder & CEO of NVIDIA. “NVIDIA’s CEO on the Next Generation of AI and MLOps” (podcast, March 3, 2022). Huang’s GPUs power modern ML research and production. Emad Mostaque – Co-founder & CEO of Stability AI. “Stable Diffusion, Stability AI, and What’s Next” (podcast, Nov. 15, 2022). Leads the company behind Stable Diffusion, which helped spark the generative-AI imaging boom. Drago Anguelov – Head of Research at Waymo. “Robustness, Safety, and Scalability at Waymo” (podcast, July 14, 2022). Covered Waymo’s self-driving AI advances and deployment challenges. Jeremy Howard – Co-founder of fast.ai. “The Simple but Profound Insight Behind Diffusion” (podcast, Jan. 5, 2023). Known for democratizing deep-learning education; discussed diffusion models and accessible AI tooling. Aidan Gomez – Co-founder & CEO of Cohere. “Scaling LLMs and Accelerating Adoption” (podcast, April 20, 2023). Co-author of “Attention Is All You Need,” he shared how Cohere delivers large-scale NLP models as a service. Chelsea Finn – Stanford Assistant Professor (AI & Robotics). “Shaping the World of Robotics with Chelsea Finn” (podcast, February 15, 2024). A pioneer in meta-learning and robotics, she detailed robots learning complex tasks like cooking. Andrew Feldman – Co-founder & CEO of Cerebras Systems. "Launching the Fastest AI Inference Solution" (podcast, August 27, 2024). Described wafer-scale AI chips achieving new training performance records. Thomas Dohmke – CEO of GitHub. “GitHub CEO on Copilot and the Future of Software Development” (podcast, June 10, 2025). Discussed building Copilot and the future of AI-assisted coding. Martin Shkreli – Founder of Godel Terminal. “From Pharma to AGI Hype, and Developing AI in Finance: Martin Shkreli’s Journey” (podcast, May 20, 2025). Shkreli reflects on his pharma controversies, prison experience, and his new AI-driven trading platform. Jarek Kutylowski – Founder & CEO of DeepL. “How DeepL Built a Translation Powerhouse with AI” (podcast, July 8, 2025). Shared how DeepL’s neural-MT rivals Google Translate through model and infrastructure innovation. == Awards and recognition == In 2010, Lukas Biewald won the Netexplorateur Award for creating the GiveWork iPhone app, which allows users to perform small tasks that assist refugees and people in developing countries. In 2010, Inc Magazine included Biewald and Van Pelt on its list of the Top 30 Entrepreneurs Under 30. == Publications == Ensuring quality in crowdsourced search relevance evaluation: The effects of training question distribution by John Le, Andy Edmonds, Vaughn Hester, Lukas Biewald. SIGIR 2010 Workshop on Crowdsourcing for Search Evaluation, July 2010. Superficial Data Analysis: Exploring Millions of Social Stereotypes by Lukas Biewald, Brendan O’Connor. O’Reilly July 2009 Biewald has co-authored 26 AI research papers from 2004 through 2018.
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Adobe PhotoDeluxe

PhotoDeluxe was a consumer-oriented image editing software line published by Adobe Systems from 1996 until July 8, 2002. At that time it was replaced by Adobe's newly launched consumer-oriented image editing software Photoshop Elements. Adobe no longer provides technical support for the PhotoDeluxe software line. PhotoDeluxe had a range of image processing capabilities for the home photographer and image handler. These included removing red-eye, cropping, and adjusting brightness, contrast, and sharpness. It also included software to extract pictures from an image scanner. Among the functionality included was the ability to dynamically resize photos and export them in a wide range of formats. It also had a range of printing options including printing multiple copies of an image on the same page. It was often bundled free with Epson scanners or as free software with new computers. == Features == Despite the critical concerns regarding the quality of the setup, Photo Deluxe supports layering, blurs, sharpening, cloning, gradient fills, color and background switches, color variations, resizing options, and many other features. Another drawback of PhotoDeluxe was that it was designed for Mac computers, so working on Windows PC was a problem for those who were unable to customize their preferences. == Versions == === Adobe PhotoDeluxe 1.0 === The first version was released in 1996 for Windows and Macintosh computers. In one year, it sold over one million copies. === Adobe PhotoDeluxe 2.0 === The new version was released in 1997 and had added features such as a Clone Tool, red-eye removal, and sample templates for making posters, cards, and calendars. It also had new special effect features. === Adobe PhotoDeluxe 3.0 === The 3rd version was released in 1998. The new features included customizable clipart settings, the ability to import photos on the web, enhanced repair activities following Guided Activities, and Adobe Connectables to add new activities. === Adobe PhotoDeluxe Home Edition (4.0) === Version 4.0 was created by the makers of Photoshop. It had advanced abilities such as tools to add animation, voice, and music to a picture. It also had features to restore photos to their original position. == History == Adobe PhotoDeluxe 1.0 was released in 1996 for Macintosh computers, initially retailing for an MSRP of $49. The software did quite well, reportedly selling over a million copies by February of the next year, primarily due to bundles with companies like Apple and Hewlett-Packard. PhotoDeluxe was primarily advertised to consumers as a way to do basic photo manipulation, such as cropping and rotating images, or creating simple cards and calendars. PhotoDeluxe 2.0 was released in 1997, and was the last version of PhotoDeluxe that Adobe made that worked on Macs. PhotoDeluxe 2.0 became the "number one selling consumer photo-editing software product in the world." PhotoDeluxe 3.0 was released in 1998, where it was rebranded as "3.0 Home Edition", as Adobe released PhotoDeluxe Business Edition later that year for a higher price. PhotoDeluxe Home Edition, unofficially called PhotoDeluxe 4.0, was released in 1999 and was the last version of PhotoDeluxe to be released. Adobe officially cancelled PhotoDeluxe on July 8, 2002, citing the presence of Photoshop and Photoshop Elements, with support being officially cancelled in mid-2003. No version of PhotoDeluxe is compatible with Windows 10, rendering the program obsolete. == Pricing == All home versions of PhotoDeluxe retailed for an MSRP of $49. PhotoDeluxe 2.0 and onwards allowed users to upgrade from a previous version of PhotoDeluxe or a competing piece of graphics software for $39. Additionally PhotoDeluxe Business Edition allowed a similar deal, allowing users to upgrade from other versions of PhotoDeluxe or a competing software for $59, instead of its normal price of $99. Adobe also offered a bundle allowing users of 1.0 or 2.0 to get 3.0 and Business Edition for $79.
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Eline Van der Velden

Eline van der Velden is a Dutch comedian, writer, actress and producer based in London, England. She is best known for her work creating Tilly Norwood, an AI-generated "actress". == Early life == Van der Velden was born on the Dutch island of Curaçao, Netherlands Antilles to Dutch businessman Steven van der Velden and physiotherapist Quirine van der Velden. She moved to the United Kingdom at age 14 to study drama and musical theatre at Tring Park School for the Performing Arts. She graduated with an MSc in physics from Imperial College London in 2008. == Career == She was nominated by the International Academy of Digital Arts and Sciences for the Lovie Awards and won Best Online Comedy in 2013 for two of her submitted entries. She has created multiple online shows such as Sketch My Life with London Hughes and Emily Hartridge and Match.com Parody. She became managing director of Makers Channel (makerschannel.co.uk), the first curated video platform in Europe in 2015. Makers Channel has been recently acquired by a Belgian media company De Persgroep, due to its success in the Netherlands. In 2016, she appeared in adverts for the Dutch shampoo brand Andrelon. Miss Holland, a comedy character created by Van der Velden, made headlines in 2016 as she asked the British public to teach her the national anthem. As an actress, she has starred in Dutch TV series De Troon, Beatrix and the Golden Calf-winning series Overspel. In Belgium, she appeared opposite Jamie Dornan in Flying Home. Van der Velden starred in the BBC Three series Putting It Out There, in which she challenges social perceptions of body hair, heels, spit, personal space, and authority figures. In 2018, she starred in the BBC One comedy series Soft Border Patrol and the BBC Three comedy series Miss Holland. In 2025, Particle6 Group, which Van der Velden founded in 2016, introduced Tilly Norwood, an AI-generated "actress" at the Zurich Film Festival. The announcement was met with outrage and a condemnation by the American actors' union SAG-AFTRA. == Awards and recognition == Miss Holland won the Best Online Comedy at the 2013 Lovie Awards, judged by Stephen Fry. The Match.com Parody video won Best Online Comedy People's Lovie Award, the people's vote. Miss Holland and Match.com Parody Date 1 were also featured in the 2013 Google Lovie Letters.
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Parents & Kids Safe AI Coalition

The Parents & Kids Safe AI Coalition is a political action committee that advocates for regulation of artificial intelligence on child safety. As of April 2026, the group is funded solely by the artificial intelligence company OpenAI, which pledged $10 million to the effort. == History == In October 2025, California Gov. Gavin Newsom vetoed Assembly Bill 1064. Sponsored by Common Sense Media, the bill would have introduced stronger child safety protections for AI chatbots. The following month, Common Sense Media founder Jim Steyer filed a ballot initiative intended to restore the "guardrails" lost in the veto. In response, OpenAI introduced a competing initiative. In January 2026, Common Sense Media and OpenAI announced that they would be working together on a compromise ballot initiative, the Parents & Kids Safe AI Act. Reporting indicated that initial outreach emails to child safety organizations failed to disclose OpenAI's involvement. Several advocacy groups signed an open letter claiming the initiative would shield AI companies from liability and undermine age verification, among other concerns. After Common Sense Media met with opposing groups in February, the ballot initiative was put on hold and the organizations involved sought to negotiate with the Legislature instead. The Parents & Kids Safe AI Coalition was founded to support this effort. In March 2026, the group reached out to some of the same groups contacted earlier, asking them to endorse its list of policy priorities. Again, some organizations reported being unaware of OpenAI's level of involvement. At least two groups withdrew from the coalition after learning about the financial ties. The priorities themselves were described as "vague but fairly uncontroversial" by The San Francisco Standard.
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