AI App Inventor

AI App Inventor — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

  • Conversational user interface

    Conversational user interface

    A conversational user interface (CUI) is a user interface for computers that emulates a conversation with a human. Historically, computers have relied on text-based user interfaces and graphical user interfaces (GUIs) (such as the user pressing a "back" button) to translate the user's desired action into commands the computer understands. While an effective mechanism of completing computing actions, there is a learning curve for the user associated with GUI. Instead, CUIs provide opportunity for the user to communicate with the computer in their natural language rather than in a syntax specific commands.

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  • TurboQuant

    TurboQuant

    TurboQuant is an online vector quantization algorithm for compressing high-dimensional Euclidean vectors while preserving their geometric structure. It was proposed in 2025 by Amir Zandieh, Majid Daliri, Majid Hadian, and Vahab Mirrokni in the paper TurboQuant: Online Vector Quantization with Near-optimal Distortion Rate. The paper lists Zandieh and Mirrokni as affiliated with Google Research, Daliri with New York University, and Hadian with Google DeepMind. The method was developed for applications including large language model (LLM) inference, key–value (KV) cache compression, vector databases, and nearest neighbor search. TurboQuant consists of two related algorithms: TurboQuantmse, which is optimized for mean squared error (MSE), and TurboQuantprod, which is optimized for unbiased inner product estimation. The algorithm uses a random rotation of input vectors, applies scalar quantizers to the rotated coordinates, and, for inner-product estimation, applies a one-bit Quantized Johnson–Lindenstrauss (QJL) transform to the residual error. == Background == Vector quantization is a compression method that maps high-dimensional vectors to a finite set of codewords. The problem has roots in Shannon's source coding theory and rate–distortion theory. In machine learning and information retrieval, vector quantization is used to reduce the memory required to store embeddings, activation vectors, and other numerical representations. In Transformer-based large language models, the KV cache stores key and value vectors from previous tokens during autoregressive decoding. The size of this cache grows with context length, the number of attention heads, and the number of concurrent requests, making it a major memory bottleneck in LLM serving. Similar compression problems appear in vector search, where large collections of embedding vectors must be stored and searched efficiently. Earlier approaches to vector quantization include product quantization, scalar quantization, and data-dependent k-means codebook construction. The TurboQuant paper argues that many existing methods either require offline preprocessing and calibration or suffer from suboptimal distortion guarantees in online settings. == Algorithm == === TurboQuantmse === TurboQuantmse is the version of the algorithm optimized for mean-squared error. For a unit vector x ∈ S d − 1 {\displaystyle x\in S^{d-1}} , the algorithm first applies a random rotation matrix Π ∈ R d × d {\displaystyle \Pi \in \mathbb {R} ^{d\times d}} and sets z = Π x {\displaystyle z=\Pi x} . Each coordinate of the rotated vector follows a shifted and scaled beta distribution, which converges to a normal distribution in high dimensions. In high dimensions, distinct coordinates also become nearly independent, allowing the algorithm to apply scalar quantizers independently to each coordinate. The scalar quantizer is constructed by solving a one-dimensional continuous k-means or Lloyd–Max quantization problem. If the centroids are c 1 , c 2 , … , c 2 b {\displaystyle c_{1},c_{2},\ldots ,c_{2^{b}}} , the quantization step stores, for each coordinate, i d x j = ⁡ a r g m i n k ∈ [ 2 b ] | z j − c k | . {\displaystyle \mathrm {idx} _{j}=\operatorname {} {arg\,min}_{k\in [2^{b}]}|z_{j}-c_{k}|.} During dequantization, the stored index for each coordinate is replaced by the corresponding centroid, giving a reconstructed rotated vector z ~ {\displaystyle {\tilde {z}}} . The algorithm then rotates back: x ~ = Π ⊤ z ~ . {\displaystyle {\tilde {x}}=\Pi ^{\top }{\tilde {z}}.} The paper gives the following bound for TurboQuantmse: D m s e ≤ 3 π 2 ⋅ 1 4 b . {\displaystyle D_{\mathrm {mse} }\leq {\frac {\sqrt {3\pi }}{2}}\cdot {\frac {1}{4^{b}}}.} It also reports finer-grained MSE values of approximately 0.36, 0.117, 0.03, and 0.009 for bit-widths b = 1 , 2 , 3 , 4 {\displaystyle b=1,2,3,4} , respectively. === TurboQuantprod === TurboQuantprod is optimized for unbiased inner-product estimation. The authors note that an MSE-optimized quantizer may introduce bias when used to estimate inner products. To address this, TurboQuantprod first applies TurboQuantmse with bit-width b − 1 {\displaystyle b-1} , then applies a one-bit Quantized Johnson–Lindenstrauss transform to the remaining residual vector. Let r = x − Q m s e − 1 ( Q m s e ( x ) ) {\displaystyle r=x-Q_{\mathrm {mse} }^{-1}(Q_{\mathrm {mse} }(x))} be the residual after MSE quantization, and let γ = ‖ r ‖ 2 {\displaystyle \gamma =\|r\|_{2}} . The QJL step stores a sign vector for the residual. For γ ≠ 0 {\displaystyle \gamma \neq 0} , this can be written using the normalized residual u = r / γ {\displaystyle u=r/\gamma } : q j l = sign ⁡ ( S u ) , {\displaystyle qjl=\operatorname {sign} (Su),} where S ∈ R d × d {\displaystyle S\in \mathbb {R} ^{d\times d}} is a random projection matrix. Since the sign function is invariant under positive rescaling, this is equivalent to sign ⁡ ( S r ) {\displaystyle \operatorname {sign} (Sr)} when r ≠ 0 {\displaystyle r\neq 0} . If γ = 0 {\displaystyle \gamma =0} , the residual correction is zero. TurboQuantprod stores the MSE quantization, the QJL sign vector, and the residual norm: Q p r o d ( x ) = [ Q m s e ( x ) , q j l , γ ] . {\displaystyle Q_{\mathrm {prod} }(x)=\left[Q_{\mathrm {mse} }(x),qjl,\gamma \right].} The dequantized vector is reconstructed as x ~ = x ~ m s e + π / 2 d γ S ⊤ q j l . {\displaystyle {\tilde {x}}={\tilde {x}}_{\mathrm {mse} }+{\frac {\sqrt {\pi /2}}{d}}\,\gamma S^{\top }qjl.} The paper proves that TurboQuantprod is unbiased for inner-product estimation: E x ~ [ ⟨ y , x ~ ⟩ ] = ⟨ y , x ⟩ . {\displaystyle \mathbb {E} _{\tilde {x}}\left[\langle y,{\tilde {x}}\rangle \right]=\langle y,x\rangle .} It also gives the distortion bound D p r o d ≤ 3 π 2 ⋅ ‖ y ‖ 2 2 d ⋅ 1 4 b . {\displaystyle D_{\mathrm {prod} }\leq {\frac {\sqrt {3\pi }}{2}}\cdot {\frac {\|y\|_{2}^{2}}{d}}\cdot {\frac {1}{4^{b}}}.} == Performance and applications == The TurboQuant paper reports that the algorithm achieves near-optimal distortion rates within a small constant factor of information-theoretic lower bounds. The authors report that, for KV cache quantization, TurboQuant achieved quality neutrality at 3.5 bits per channel and marginal degradation at 2.5 bits per channel. In long-context LLM experiments using Llama 3.1 8B Instruct, the paper evaluated the method on a "needle-in-a-haystack" retrieval task with document lengths from 4,000 to 104,000 tokens. It reported that TurboQuant matched the uncompressed full-precision baseline while using more than 4× compression, and compared the method against PolarQuant, SnapKV, PyramidKV, and KIVI. Google Research stated that TurboQuant was evaluated on long-context benchmarks including LongBench, Needle in a Haystack, ZeroSCROLLS, RULER, and L-Eval using open-source models including Gemma and Mistral. According to a report in Tom's Hardware, Google described the method as reducing KV-cache memory by at least six times and achieving up to an eightfold improvement in attention-logit computation on Nvidia H100 GPUs compared with unquantized 32-bit keys. TurboQuant has also been applied to nearest-neighbor vector search. The original paper reports experiments on DBpedia entity embeddings and GloVe embeddings, comparing TurboQuant with product quantization and other vector-search quantization baselines. == Relationship to other methods == TurboQuant is related to several methods for efficient large language model inference and high-dimensional search: Product quantization – a vector quantization technique widely used for approximate nearest-neighbor search Quantization (machine learning) – reducing the numerical precision of weights, activations, or cached tensors in machine learning models PagedAttention – a memory-management algorithm for LLM serving that reduces fragmentation in the KV cache Johnson–Lindenstrauss lemma – a result in high-dimensional geometry used in random projection methods Lloyd's algorithm – an algorithm for scalar and vector quantization, including k-means-style codebook construction Unlike PagedAttention, which focuses on memory allocation and cache layout, TurboQuant reduces the numerical storage cost of the vectors themselves. Unlike many product-quantization methods, TurboQuant is designed to be data-oblivious and online, avoiding dataset-specific codebook training. == Limitations == The strongest performance claims for TurboQuant come from the original paper and Google Research's own publication. Coverage in technology media has noted that the broader impact of the method will depend on real-world implementation details, workloads, and hardware architectures.

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  • Virtual data room

    Virtual data room

    A virtual data room (sometimes called a VDR or Deal Room) is an online repository of information that is used for the storing and distribution of documents. In many cases, a virtual data room is used to facilitate the due diligence process during an M&A transaction, loan syndication, or private equity and venture capital transactions. This due diligence process has traditionally used a physical data room to accomplish the disclosure of documents. For reasons of cost, efficiency and security, virtual data rooms have widely replaced the more traditional physical data room. A virtual data room is an extranet to which the bidders and their advisers are given access via the internet. An extranet is essentially a website with limited controlled access, using a secure log-on supplied by the vendor, which can be disabled at any time, by the vendor, if a bidder withdraws. Much of the information released is confidential and restrictions are applied to the viewer's ability to release this to third parties (by means of forwarding, copying or printing). This can be effectively applied to protect the data using digital rights management. The virtual data room provides access to secure documents for authorized users through a dedicated web site, or through secure agent applications. In the process of mergers and acquisitions the data room is set up as part of the central repository of data relating to companies or divisions being acquired or sold. The data room enables the interested parties to view information relating to the business in a controlled environment where confidentiality can be preserved. Conventionally this was achieved by establishing a supervised, physical data room in secure premises with controlled access. In most cases, with a physical data room, only one bidder team can access the room at a time. A virtual data room is designed to have the same advantages as a conventional data room (controlling access, viewing, copying and printing, etc.) with fewer disadvantages. Due to their increased efficiency, many businesses and industries have moved to using virtual data rooms instead of physical data rooms. In 2006, a spokesperson for a company which sets up virtual deal rooms was reported claiming that the process reduced the bidding process by about thirty days compared to physical data rooms. In the process of startup fundraising, a virtual data room is set up to be a central location for key data, documents, and financials. These are shared with venture capital and angel investors and allows them to streamline due diligence. == Application == Any business dealing with private data can apply VDRs when secure transaction processing is required. This includes financial institutions that need to negotiate confidential customer information without involving third parties. VDRs have traditionally been used for IPOs and real estate asset management. Technology companies may use them to exchange and review code or confidential data needed for operations. The same is true for clients, who entrust their valuable code only to the most qualified people in the organisation. The code is not something that can be printed out and brought in a folder. It resides on a computer and must be used together. VDR can find application in any business that manages data in the form of documents, especially law firms, financial advisers or the B2B sector. The latter work with documents that must always be handled and controlled confidentially, and it is difficult to store them securely when they are on a server that other people can access. In addition, in B2B, it is important to close the deal as quickly as possible: the average sales cycle is one to three months. VDR can be compared to a locked filing cabinet where all those folders and documents are kept. It automates the mathematics of pricing to prevent revenue leakage, and initially integrates CRM to ensure accurate synchronisation of all account data, which is important for B2B in particular and sales in general. While virtual data rooms offer many advantages, they are not suitable for every industry. For example, some governments may decide to continue using physical data rooms for highly confidential information sharing. The damage from potential cyberattacks and data breaches exceeds the benefits offered by virtual data rooms. In such cases, the use of VDRs is not considered. Data breaches have particularly affected the US healthcare system from March 2021 to March 2022 - according to IBM Security the cost of the breach was a record high of $10.1 million.

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  • Ontology alignment

    Ontology alignment

    Ontology alignment, or ontology matching, is the process of determining correspondences between concepts in ontologies. A set of correspondences is also called an alignment. The phrase takes on a slightly different meaning, in computer science, cognitive science or philosophy. == Computer science == For computer scientists, concepts are expressed as labels for data. Historically, the need for ontology alignment arose out of the need to integrate heterogeneous databases, ones developed independently and thus each having their own data vocabulary. In the Semantic Web context involving many actors providing their own ontologies, ontology matching has taken a critical place for helping heterogeneous resources to interoperate. Ontology alignment tools find classes of data that are semantically equivalent, for example, "truck" and "lorry". The classes are not necessarily logically identical. According to Euzenat and Shvaiko (2007), there are three major dimensions for similarity: syntactic, external, and semantic. Coincidentally, they roughly correspond to the dimensions identified by Cognitive Scientists below. A number of tools and frameworks have been developed for aligning ontologies, some with inspiration from Cognitive Science and some independently. Ontology alignment tools have generally been developed to operate on database schemas, XML schemas, taxonomies, formal languages, entity-relationship models, dictionaries, and other label frameworks. They are usually converted to a graph representation before being matched. Since the emergence of the Semantic Web, such graphs can be represented in the Resource Description Framework line of languages by triples of the form , as illustrated in the Notation 3 syntax. In this context, aligning ontologies is sometimes referred to as "ontology matching". The problem of Ontology Alignment has been tackled recently by trying to compute matching first and mapping (based on the matching) in an automatic fashion. Systems like DSSim, X-SOM or COMA++ obtained at the moment very high precision and recall. The Ontology Alignment Evaluation Initiative aims to evaluate, compare and improve the different approaches. === Formal definition === Given two ontologies i = ⟨ C i , R i , I i , T i , V i ⟩ {\displaystyle i=\langle C_{i},R_{i},I_{i},T_{i},V_{i}\rangle } and j = ⟨ C j , R j , I j , T j , V j ⟩ {\displaystyle j=\langle C_{j},R_{j},I_{j},T_{j},V_{j}\rangle } where C {\displaystyle C} is the set of classes, R {\displaystyle R} is the set of relations, I {\displaystyle I} is the set of individuals, T {\displaystyle T} is the set of data types, and V {\displaystyle V} is the set of values, we can define different types of (inter-ontology) relationships. Such relationships will be called, all together, alignments and can be categorized among different dimensions: similarity vs logic: this is the difference between matchings (predicating about the similarity of ontology terms), and mappings (logical axioms, typically expressing logical equivalence or inclusion among ontology terms) atomic vs complex: whether the alignments we considered are one-to-one, or can involve more terms in a query-like formulation (e.g., LAV/GAV mapping) homogeneous vs heterogeneous: do the alignments predicate on terms of the same type (e.g., classes are related only to classes, individuals to individuals, etc.) or we allow heterogeneity in the relationship? type of alignment: the semantics associated to an alignment. It can be subsumption, equivalence, disjointness, part-of or any user-specified relationship. Subsumption, atomic, homogeneous alignments are the building blocks to obtain richer alignments, and have a well defined semantics in every Description Logic. Let's now introduce more formally ontology matching and mapping. An atomic homogeneous matching is an alignment that carries a similarity degree s ∈ [ 0 , 1 ] {\displaystyle s\in [0,1]} , describing the similarity of two terms of the input ontologies i {\displaystyle i} and j {\displaystyle j} . Matching can be either computed, by means of heuristic algorithms, or inferred from other matchings. Formally we can say that, a matching is a quadruple m = ⟨ i d , t i , t j , s ⟩ {\displaystyle m=\langle id,t_{i},t_{j},s\rangle } , where t i {\displaystyle t_{i}} and t j {\displaystyle t_{j}} are homogeneous ontology terms, s {\displaystyle s} is the similarity degree of m {\displaystyle m} . A (subsumption, homogeneous, atomic) mapping is defined as a pair μ = ⟨ t i , t j ⟩ {\displaystyle \mu =\langle t_{i},t_{j}\rangle } , where t i {\displaystyle t_{i}} and t j {\displaystyle t_{j}} are homogeneous ontology terms. == Cognitive science == For cognitive scientists interested in ontology alignment, the "concepts" are nodes in a semantic network that reside in brains as "conceptual systems." The focal question is: if everyone has unique experiences and thus different semantic networks, then how can we ever understand each other? This question has been addressed by a model called ABSURDIST (Aligning Between Systems Using Relations Derived Inside Systems for Translation). Three major dimensions have been identified for similarity as equations for "internal similarity, external similarity, and mutual inhibition." == Ontology alignment methods == Two sub research fields have emerged in ontology mapping, namely monolingual ontology mapping and cross-lingual ontology mapping. The former refers to the mapping of ontologies in the same natural language, whereas the latter refers to "the process of establishing relationships among ontological resources from two or more independent ontologies where each ontology is labelled in a different natural language". Existing matching methods in monolingual ontology mapping are discussed in Euzenat and Shvaiko (2007). Approaches to cross-lingual ontology mapping are presented in Fu et al. (2011).

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  • Automated decision-making

    Automated decision-making

    Automated decision-making (ADM) is the use of data, machines and algorithms to make decisions in a range of contexts, including public administration, business, health, education, law, employment, transport, media and entertainment, with varying degrees of human oversight or intervention. ADM may involve large-scale data from a range of sources, such as databases, text, social media, sensors, images or speech, that is processed using various technologies including computer software, algorithms, machine learning, natural language processing, artificial intelligence, augmented intelligence and robotics. The increasing use of automated decision-making systems (ADMS) across a range of contexts presents many benefits and challenges to human society requiring consideration of the technical, legal, ethical, societal, educational, economic and health consequences. == Overview == There are different definitions of ADM based on the level of automation involved. Some definitions suggests ADM involves decisions made through purely technological means without human input, such as the EU's General Data Protection Regulation (Article 22). However, ADM technologies and applications can take many forms ranging from decision-support systems that make recommendations for human decision-makers to act on, sometimes known as augmented intelligence or 'shared decision-making', to fully automated decision-making processes that make decisions on behalf of individuals or organizations without human involvement. Models used in automated decision-making systems can be as simple as checklists and decision trees through to artificial intelligence and deep neural networks (DNN). Since the 1950s computers have gone from being able to do basic processing to having the capacity to undertake complex, ambiguous and highly skilled tasks such as image and speech recognition, gameplay, scientific and medical analysis and inferencing across multiple data sources. ADM is now being increasingly deployed across all sectors of society and many diverse domains from entertainment to transport. An ADM system (ADMS) may involve multiple decision points, data sets, and technologies (ADMT) and may sit within a larger administrative or technical system such as a criminal justice system or business process. == Data == Automated decision-making involves using data as input to be analyzed within a process, model, or algorithm or for learning and generating new models. ADM systems may use and connect a wide range of data types and sources depending on the goals and contexts of the system, for example, sensor data for self-driving cars and robotics, identity data for security systems, demographic and financial data for public administration, medical records in health, criminal records in law. This can sometimes involve vast amounts of data and computing power. === Data quality === The quality of the available data and its ability to be used in ADM systems is fundamental to the outcomes. It is often highly problematic for many reasons. Datasets are often highly variable; corporations or governments may control large-scale data, restricted for privacy or security reasons, incomplete, biased, limited in terms of time or coverage, measuring and describing terms in different ways, and many other issues. For machines to learn from data, large corpora are often required, which can be challenging to obtain or compute; however, where available, they have provided significant breakthroughs, for example, in diagnosing chest X-rays. == ADM technologies == Automated decision-making technologies (ADMT) are software-coded digital tools that automate the translation of input data to output data, contributing to the function of automated decision-making systems. There are a wide range of technologies in use across ADM applications and systems. ADMTs involving basic computational operations Search (includes 1-2-1, 1-2-many, data matching/merge) Matching (two different things) Mathematical Calculation (formula) ADMTs for assessment and grouping: User profiling Recommender systems Clustering Classification Feature learning Predictive analytics (includes forecasting) ADMTs relating to space and flows: Social network analysis (includes link prediction) Mapping Routing ADMTs for processing of complex data formats Image processing Audio processing Natural Language Processing (NLP) Other ADMT Business rules management systems Time series analysis Anomaly detection Modelling/Simulation === Machine learning === Machine learning (ML) involves training computer programs through exposure to large data sets and examples to learn from experience and solve problems. Machine learning can be used to generate and analyse data as well as make algorithmic calculations and has been applied to image and speech recognition, translations, text, data and simulations. While machine learning has been around for some time, it is becoming increasingly powerful due to recent breakthroughs in training deep neural networks (DNNs), and dramatic increases in data storage capacity and computational power with GPU coprocessors and cloud computing. Machine learning systems based on foundation models run on deep neural networks and use pattern matching to train a single huge system on large amounts of general data such as text and images. Early models tended to start from scratch for each new problem however since the early 2020s many are able to be adapted to new problems. Examples of these technologies include Open AI's DALL-E (an image creation program) and their various GPT language models, and Google's PaLM language model program. == Applications == ADM is being used to replace or augment human decision-making by both public and private-sector organisations for a range of reasons including to help increase consistency, improve efficiency, reduce costs and enable new solutions to complex problems. === Debate === Research and development are underway into uses of technology to assess argument quality, assess argumentative essays and judge debates. Potential applications of these argument technologies span education and society. Scenarios to consider, in these regards, include those involving the assessment and evaluation of conversational, mathematical, scientific, interpretive, legal, and political argumentation and debate. === Law === In legal systems around the world, algorithmic tools such as risk assessment instruments (RAI), are being used to supplement or replace the human judgment of judges, civil servants and police officers in many contexts. In the United States RAI are being used to generate scores to predict the risk of recidivism in pre-trial detention and sentencing decisions, evaluate parole for prisoners and to predict "hot spots" for future crime. These scores may result in automatic effects or may be used to inform decisions made by officials within the justice system. In Canada ADM has been used since 2014 to automate certain activities conducted by immigration officials and to support the evaluation of some immigrant and visitor applications. === Economics === Automated decision-making systems are used in certain computer programs to create buy and sell orders related to specific financial transactions and automatically submit the orders in the international markets. Computer programs can automatically generate orders based on predefined set of rules using trading strategies which are based on technical analyses, advanced statistical and mathematical computations, or inputs from other electronic sources. === Business === ==== Continuous auditing ==== Continuous auditing uses advanced analytical tools to automate auditing processes. It can be utilized in the private sector by business enterprises and in the public sector by governmental organizations and municipalities. As artificial intelligence and machine learning continue to advance, accountants and auditors may make use of increasingly sophisticated algorithms which make decisions such as those involving determining what is anomalous, whether to notify personnel, and how to prioritize those tasks assigned to personnel. === Media and entertainment === Digital media, entertainment platforms, and information services increasingly provide content to audiences via automated recommender systems based on demographic information, previous selections, collaborative filtering or content-based filtering. This includes music and video platforms, publishing, health information, product databases and search engines. Many recommender systems also provide some agency to users in accepting recommendations and incorporate data-driven algorithmic feedback loops based on the actions of the system user. Large-scale machine learning language models and image creation programs being developed by companies such as OpenAI and Google in the 2020s have restricted access however they are likely to have widespread application in fields such as advertising, copywriting, stock imagery and gra

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  • Randomized rounding

    Randomized rounding

    In computer science and operations research, randomized rounding is a widely used approach for designing and analyzing approximation algorithms. Many combinatorial optimization problems are computationally intractable to solve exactly (to optimality). For such problems, randomized rounding can be used to design fast (polynomial time) approximation algorithms—that is, algorithms that are guaranteed to return an approximately optimal solution given any input. The basic idea of randomized rounding is to convert an optimal solution of a relaxation of the problem into an approximately-optimal solution to the original problem. The resulting algorithm is usually analyzed using the probabilistic method. == Overview == The basic approach has three steps: Formulate the problem to be solved as an integer linear program (ILP). Compute an optimal fractional solution x {\displaystyle x} to the linear programming relaxation (LP) of the ILP. Round the fractional solution x {\displaystyle x} of the LP to an integer solution x ′ {\displaystyle x'} of the ILP. (Although the approach is most commonly applied with linear programs, other kinds of relaxations are sometimes used. For example, see Goemans' and Williamson's semidefinite programming-based Max-Cut approximation algorithm.) In the first step, the challenge is to choose a suitable integer linear program. Familiarity with linear programming, in particular modelling using linear programs and integer linear programs, is required. For many problems, there is a natural integer linear program that works well, such as in the Set Cover example below. (The integer linear program should have a small integrality gap; indeed randomized rounding is often used to prove bounds on integrality gaps.) In the second step, the optimal fractional solution can typically be computed in polynomial time using any standard linear programming algorithm. In the third step, the fractional solution must be converted into an integer solution (and thus a solution to the original problem). This is called rounding the fractional solution. The resulting integer solution should (provably) have cost not much larger than the cost of the fractional solution. This will ensure that the cost of the integer solution is not much larger than the cost of the optimal integer solution. The main technique used to do the third step (rounding) is to use randomization, and then to use probabilistic arguments to bound the increase in cost due to the rounding (following the probabilistic method from combinatorics). Therein, probabilistic arguments are used to show the existence of discrete structures with desired properties. In this context, one uses such arguments to show the following: Given any fractional solution x {\displaystyle x} of the LP, with positive probability the randomized rounding process produces an integer solution x ′ {\displaystyle x'} that approximates x {\displaystyle x} according to some desired criterion. Finally, to make the third step computationally efficient, one either shows that x ′ {\displaystyle x'} approximates x {\displaystyle x} with high probability (so that the step can remain randomized) or one derandomizes the rounding step, typically using the method of conditional probabilities. The latter method converts the randomized rounding process into an efficient deterministic process that is guaranteed to reach a good outcome. == Example: the set cover problem == The following example illustrates how randomized rounding can be used to design an approximation algorithm for the set cover problem. Fix any instance ⟨ c , S ⟩ {\displaystyle \langle c,{\mathcal {S}}\rangle } of set cover over a universe U {\displaystyle {\mathcal {U}}} . === Computing the fractional solution === For step 1, let IP be the standard integer linear program for set cover for this instance. For step 2, let LP be the linear programming relaxation of IP, and compute an optimal solution x ∗ {\displaystyle x^{}} to LP using any standard linear programming algorithm. This takes time polynomial in the input size. The feasible solutions to LP are the vectors x {\displaystyle x} that assign each set s ∈ S {\displaystyle s\in {\mathcal {S}}} a non-negative weight x s {\displaystyle x_{s}} , such that, for each element e ∈ U {\displaystyle e\in {\mathcal {U}}} , x ′ {\displaystyle x'} covers e {\displaystyle e} —the total weight assigned to the sets containing e {\displaystyle e} is at least 1, that is, ∑ s ∋ e x s ≥ 1. {\displaystyle \sum _{s\ni e}x_{s}\geq 1.} The optimal solution x ∗ {\displaystyle x^{}} is a feasible solution whose cost ∑ s ∈ S c ( S ) x s ∗ {\displaystyle \sum _{s\in {\mathcal {S}}}c(S)x_{s}^{}} is as small as possible. Note that any set cover C {\displaystyle {\mathcal {C}}} for S {\displaystyle {\mathcal {S}}} gives a feasible solution x {\displaystyle x} (where x s = 1 {\displaystyle x_{s}=1} for s ∈ C {\displaystyle s\in {\mathcal {C}}} , x s = 0 {\displaystyle x_{s}=0} otherwise). The cost of this C {\displaystyle {\mathcal {C}}} equals the cost of x {\displaystyle x} , that is, ∑ s ∈ C c ( s ) = ∑ s ∈ S c ( s ) x s . {\displaystyle \sum _{s\in {\mathcal {C}}}c(s)=\sum _{s\in {\mathcal {S}}}c(s)x_{s}.} In other words, the linear program LP is a relaxation of the given set-cover problem. Since x ∗ {\displaystyle x^{}} has minimum cost among feasible solutions to the LP, the cost of x ∗ {\displaystyle x^{}} is a lower bound on the cost of the optimal set cover. === Randomized rounding step === In step 3, we must convert the minimum-cost fractional set cover x ∗ {\displaystyle x^{}} into a feasible integer solution x ′ {\displaystyle x'} (corresponding to a true set cover). The rounding step should produce an x ′ {\displaystyle x'} that, with positive probability, has cost within a small factor of the cost of x ∗ {\displaystyle x^{}} .Then (since the cost of x ∗ {\displaystyle x^{}} is a lower bound on the cost of the optimal set cover), the cost of x ′ {\displaystyle x'} will be within a small factor of the optimal cost. As a starting point, consider the most natural rounding scheme: For each set s ∈ S {\displaystyle s\in {\mathcal {S}}} in turn, take x s ′ = 1 {\displaystyle x'_{s}=1} with probability min ( 1 , x s ∗ ) {\displaystyle \min(1,x_{s}^{})} , otherwise take x s ′ = 0 {\displaystyle x'_{s}=0} . With this rounding scheme, the expected cost of the chosen sets is at most ∑ s c ( s ) x s ∗ {\displaystyle \sum _{s}c(s)x_{s}^{}} , the cost of the fractional cover. This is good. Unfortunately the coverage is not good. When the variables x s ∗ {\displaystyle x_{s}^{}} are small, the probability that an element e {\displaystyle e} is not covered is about ∏ s ∋ e 1 − x s ∗ ≈ ∏ s ∋ e exp ⁡ ( − x s ∗ ) = exp ⁡ ( − ∑ s ∋ e x s ∗ ) ≈ exp ⁡ ( − 1 ) . {\displaystyle \prod _{s\ni e}1-x_{s}^{}\approx \prod _{s\ni e}\exp(-x_{s}^{})=\exp {\Big (}-\sum _{s\ni e}x_{s}^{}{\Big )}\approx \exp(-1).} So only a constant fraction of the elements will be covered in expectation. To make x ′ {\displaystyle x'} cover every element with high probability, the standard rounding scheme first scales up the rounding probabilities by an appropriate factor λ > 1 {\displaystyle \lambda >1} . Here is the standard rounding scheme: Fix a parameter λ ≥ 1 {\displaystyle \lambda \geq 1} . For each set s ∈ S {\displaystyle s\in {\mathcal {S}}} in turn, take x s ′ = 1 {\displaystyle x'_{s}=1} with probability min ( λ x s ∗ , 1 ) {\displaystyle \min(\lambda x_{s}^{},1)} , otherwise take x s ′ = 0 {\displaystyle x'_{s}=0} . Scaling the probabilities up by λ {\displaystyle \lambda } increases the expected cost by λ {\displaystyle \lambda } , but makes coverage of all elements likely. The idea is to choose λ {\displaystyle \lambda } as small as possible so that all elements are provably covered with non-zero probability. Here is a detailed analysis. ==== Lemma (approximation guarantee for rounding scheme) ==== Fix λ = ln ⁡ ( 2 | U | ) {\displaystyle \lambda =\ln(2|{\mathcal {U}}|)} . With positive probability, the rounding scheme returns a set cover x ′ {\displaystyle x'} of cost at most 2 ln ⁡ ( 2 | U | ) c ⋅ x ∗ {\displaystyle 2\ln(2|{\mathcal {U}}|)c\cdot x^{}} (and thus of cost O ( log ⁡ | U | ) {\displaystyle O(\log |{\mathcal {U}}|)} times the cost of the optimal set cover). (Note: with care the O ( log ⁡ | U | ) {\displaystyle O(\log |{\mathcal {U}}|)} can be reduced to ln ⁡ ( | U | ) + O ( log ⁡ log ⁡ | U | ) {\displaystyle \ln(|{\mathcal {U}}|)+O(\log \log |{\mathcal {U}}|)} .) ==== Proof ==== The output x ′ {\displaystyle x'} of the random rounding scheme has the desired properties as long as none of the following "bad" events occur: the cost c ⋅ x ′ {\displaystyle c\cdot x'} of x ′ {\displaystyle x'} exceeds 2 λ c ⋅ x ∗ {\displaystyle 2\lambda c\cdot x^{}} , or for some element e {\displaystyle e} , x ′ {\displaystyle x'} fails to cover e {\displaystyle e} . The expectation of each x s ′ {\displaystyle x'_{s}} is at most λ x s ∗ {\displaystyle \lambda x_{s

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  • Umbrella review

    Umbrella review

    In medical research, an umbrella review is a review of systematic reviews or meta-analyses. They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. Umbrella reviews are among the highest levels of evidence currently available in medicine. By summarizing information from multiple overview articles, umbrella reviews make it easier to review the evidence and allow for comparison of results between each of the individual reviews. Umbrella reviews may address a broader question than a typical review, such as discussing multiple different treatment comparisons instead of only one. They are especially useful for developing guidelines and clinical practice, and when comparing competing interventions.

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  • Kinodynamic planning

    Kinodynamic planning

    In robotics and motion planning, kinodynamic planning is a class of problems for which velocity, acceleration, and force/torque bounds must be satisfied, together with kinematic constraints such as avoiding obstacles. The term was coined by Bruce Donald, Pat Xavier, John Canny, and John Reif. Donald et al. developed the first polynomial-time approximation schemes (PTAS) for the problem. By providing a provably polynomial-time ε-approximation algorithm, they resolved a long-standing open problem in optimal control. Their first paper considered time-optimal control ("fastest path") of a point mass under Newtonian dynamics, amidst polygonal (2D) or polyhedral (3D) obstacles, subject to state bounds on position, velocity, and acceleration. Later they extended the technique to many other cases, for example, to 3D open-chain kinematic robots under full Lagrangian dynamics. == Modern approaches == Since the foundational theoretical work of the 1990s, the field has evolved significantly with new algorithmic approaches that address the computational and practical limitations of early methods. === Sampling-based methods === Many practical heuristic algorithms based on stochastic optimization and iterative sampling have been developed by a wide range of authors to address the kinodynamic planning problem. Popular approaches include extensions of RRT algorithms such as RRT for kinodynamic systems, and sampling-based methods like Model Predictive Path Integral (MPPI) control. These stochastic techniques have been shown to work well in practice and can handle complex, high-dimensional state spaces more efficiently than deterministic methods. However, all motion planning methods are subject to the PSPACE-hardnesss of classical motion planning even without dynamics, which means (assuming the usual structural complexity conjectures) they all can be worst-case exponential-time in the state-space dimension (the number of degrees of freedom). On the other hand, the deterministic methods have provable guarantees of completeness, accuracy, and complexity (for fixed dimension, they are polynomial-time not only in the geometric complexity, but also in ( 1 / ε ) {\displaystyle (1/\varepsilon )} , the closeness of the desired approximation), whereas most of the recent heuristic/stochastic methods sacrifice at least one of these criteria. === Mixed-integer optimization approaches === Recent advances in mixed-integer programming have enabled new deterministic approaches to kinodynamic planning. These methods formulate the planning problem as an optimization task that simultaneously determines the spatial path and control sequence while respecting all kinodynamic constraints. By using techniques such as McCormick envelopes to handle bilinear constraints, these approaches can provide globally optimal solutions with mathematical guarantees while achieving significant computational speedups over traditional methods. === Genetic algorithm approaches === Genetic algorithms have also been adapted for kinodynamic planning, particularly for gradient-free optimization in challenging terrain. These methods use evolutionary computation to optimize trajectories over receding horizons, with specialized mutation operators that ensure vehicle controls remain within operational limits. This approach is particularly useful when dealing with non-differentiable cost functions or when gradient information is unavailable or unreliable. === Three-dimensional terrain planning === The foundational theoretical work of the 1990s was extended to higher degrees of freedom, and even to n {\displaystyle n} -link, 3D open-chain kinematic robots under full Lagrangian dynamics. However, many of the subsequent heuristic techniques (typically employing stochastic optimization) were confined to planar environments. More recent kinodynamic planning has extended beyond these planar environments to handle complex 3D terrains represented as simplicial complexes or triangular meshes. This advancement is particularly important for applications such as autonomous vehicle navigation in off-road environments, where elevation changes and terrain geometry significantly impact vehicle dynamics. These methods must account for pitch angles, surface curvature, and the coupling between terrain geometry and vehicle kinodynamic constraints. == Performance and guarantees == The landscape of performance guarantees in kinodynamic planning has evolved considerably. While early heuristic methods could not guarantee optimality, recent mixed-integer approaches have demonstrated the ability to find globally optimal solutions with proven constraint satisfaction. Experimental comparisons have shown that modern optimization-based planners can achieve execution times several orders of magnitude faster than sampling-based methods while maintaining strict adherence to kinodynamic constraints. However, the choice of method often depends on the specific application requirements. Sampling-based methods remain valuable for their ability to quickly find feasible solutions in high-dimensional spaces and their robustness to modeling uncertainties. Optimization-based methods excel when optimality guarantees and constraint compliance are critical, particularly in safety-critical applications. == Applications == Kinodynamic planning finds applications across numerous domains including: Autonomous vehicles: Path planning for cars, trucks, and other ground vehicles that must respect acceleration, steering, and velocity limits Aerial robotics: Trajectory planning for quadrotors and other unmanned aerial vehicles with dynamic constraints Manipulation: Planning for robotic arms where joint velocities, accelerations, and torques are limited Legged locomotion: Footstep and trajectory planning for walking and running robots Space robotics: Planning under thrust and fuel constraints for spacecraft and rovers

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  • Pedagogical agent

    Pedagogical agent

    A pedagogical agent is a concept borrowed from computer science and artificial intelligence and applied to education, usually as part of an intelligent tutoring system (ITS). It is a simulated human-like interface between the learner and the content, in an educational environment. A pedagogical agent is designed to model the type of interactions between a student and another person. Mabanza and de Wet define it as "a character enacted by a computer that interacts with the user in a socially engaging manner". A pedagogical agent can be assigned different roles in the learning environment, such as tutor or co-learner, depending on the desired purpose of the agent. "A tutor agent plays the role of a teacher, while a co-learner agent plays the role of a learning companion". == History == The history of Pedagogical Agents is closely aligned with the history of computer animation. As computer animation progressed, it was adopted by educators to enhance computerized learning by including a lifelike interface between the program and the learner. The first versions of a pedagogical agent were more cartoon than person, like Microsoft's Clippy which helped users of Microsoft Office load and use the program's features in 1997. However, with developments in computer animation, pedagogical agents can now look lifelike. By 2006 there was a call to develop modular, reusable agents to decrease the time and expertise required to create a pedagogical agent. There was also a call in 2009 to enact agent standards. The standardization and re-usability of pedagogical agents is less of an issue since the decrease in cost and widespread availability of animation tools. Individualized pedagogical agents can be found across disciplines including medicine, math, law, language learning, automotive, and armed forces. They are used in applications directed to every age, from preschool to adult. == Learning theories related to pedagogical agent design == === Distributed cognition theory === Distributed cognition theory is the method in which cognition progresses in the context of collaboration with others. Pedagogical agents can be designed to assist the cognitive transfer to the learner, operating as artifacts or partners with collaborative role in learning. To support the performance of an action by the user, the pedagogical agent can act as a cognitive tool as long as the agent is equipped with the knowledge that the user lacks. The interactions between the user and the pedagogical agent can facilitate a social relationship. The pedagogical agent may fulfill the role of a working partner. === Socio-cultural learning theory === Socio-cultural learning theory is how the user develops when they are involved in learning activities in which there is interaction with other agents. A pedagogical agent can: intervene when the user requests, provide support for tasks that the user cannot address, and potentially extend the learners cognitive reach. Interaction with the pedagogical agent may elicit a variety of emotions from the learner. The learner may become excited, confused, frustrated, and/or discouraged. These emotions affect the learners' motivation. === Extraneous Cognitive Load === Extraneous cognitive load is the extra effort being exerted by an individual's working memory due to the way information is being presented. A pedagogical agent can increase the user's cognitive load by distracting them and becoming the focus of their attention, causing split attention between the instructional material and the agent. Agents can reduce the perceived cognitive load by providing narration and personalization that can also promote a user's interest and motivation. While research on the reduction of cognitive load from pedagogical agents is minimal, more studies have shown that agents do not increase it. == Effectiveness == It has been suggested by researchers that pedagogical agents may take on different roles in the learning environment. Examples of these roles are: supplanting, scaffolding, coaching, testing, or demonstrating or modelling a procedure. A pedagogical agent as a tutor has not been demonstrated to add any benefit to an educational strategy in equivalent lessons with and without a pedagogical agent. According to Richard Mayer, there is some support in research for pedagogical agent increasing learning, but only as a presenter of social cues. A co-learner pedagogical agent is believed to increase the student's self-efficacy. By pointing out important features of instructional content, a pedagogical agent can fulfill the signaling function, which research on multimedia learning has shown to enhance learning. Research has demonstrated that human-human interaction may not be completely replaced by pedagogical agents, but learners may prefer the agents to non-agent multimedia systems. This finding is supported by social agency theory. Much like the varying effectiveness of the pedagogical agent roles in the learning environment, agents that take into account the user's affect have had mixed results. Research has shown pedagogical agents that make use of the users’ affect have been found to increase user knowledge retention, motivation, and perceived self-efficacy. However, with such a broad range of modalities in affective expressions, it is often difficult to utilize them. Additionally, having agents detect a user's affective state with precision remains challenging, as displays of affect are different across individuals. == Design == === Attractiveness === The appearance of a pedagogical agent can be manipulated to meet the learning requirements. The attractiveness of a pedagogical agent can enhance student's learning when the users were the opposite gender of the pedagogical agent. Male students prefer a sexy appearance of a female pedagogical agents and dislike the sexy appearance of male agents. Female students were not attracted by the sexy appearance of either male or female pedagogical agents. === Affective Response === Pedagogical agents have reached a point where they can convey and elicit emotion, but also reason about and respond to it. These agents are often designed to elicit and respond to affective actions from users through various modalities such as speech, facial expressions, and body gestures. They respond to the affective state of the given user, and make use of these modalities using a wide array of sensors incorporated into the design of the agent. Specifically in education and training applications, pedagogical agents are often designed to increasingly recognize when users or learners exhibit frustration, boredom, confusion, and states of flow. The added recognition in these agents is a step toward making them more emotionally intelligent, comforting and motivating the users as they interact. === Digital Representation === The design of a pedagogical agent often begins with its digital representation, whether it will be 2D or 3D and static or animated. Several studies have developed pedagogical agents that were both static and animated, then evaluated the relative benefits. Similar to other design considerations, the improved learning from static or animated agents remains questionable. One study showed that the appearance of an agent portrayed using a static image can impact a user's recall, based on the visual appearance. Other research found results that suggest static agent images improve learning outcomes. However, several other studies found user's learned more when the pedagogical agent was animated rather than static. Recently a meta-analysis of such research found a negligible improvement in learning via pedagogical agents, suggesting more work needs to be done in the area to support any claims.

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  • Hall circles

    Hall circles

    Hall circles (also known as M-circles and N-circles) are a graphical tool in control theory used to obtain values of a closed-loop transfer function from the Nyquist plot (or the Nichols plot) of the associated open-loop transfer function. Hall circles have been introduced in control theory by Albert C. Hall in his thesis. == Construction == Consider a closed-loop linear control system with open-loop transfer function given by transfer function G ( s ) {\displaystyle G(s)} and with a unit gain in the feedback loop. The closed-loop transfer function is given by T ( s ) = G ( s ) 1 + G ( s ) {\textstyle T(s)={\frac {G(s)}{1+G(s)}}} . To check the stability of T(s), it is possible to use the Nyquist stability criterion with the Nyquist plot of the open-loop transfer function G(s). Note, however, that the Nyquist plot of G(s) does not give the actual values of T(s). To get this information from the G(s)-plane, Hall proposed to construct the locus of points in the G(s)-plane such that T(s) has constant magnitude and also the locus of points in the G(s)-plane such that T(s) has constant phase angle. Given a positive real value M representing a fixed magnitude, and denoting G(s) by z, the points satisfying M = | T ( s ) | = | G ( s ) | | 1 + G ( s ) | = | z | | 1 + z | {\displaystyle M=|T(s)|={\frac {|G(s)|}{|1+G(s)|}}={\frac {|z|}{|1+z|}}} are given by the points z in the G(s)-plane such that the ratio of the distance between z and 0 and the distance between z and -1 is equal to M. The points z satisfying this locus condition are circles of Apollonius, and this locus is known in the context of control systems as M-circles. Given a positive real value N representing a phase angle, the points satisfying N = arg ⁡ [ G ( s ) 1 + G ( s ) ] = arg ⁡ [ G ( s ) ] − arg ⁡ [ 1 + G ( s ) ] = arg ⁡ [ z ] − arg ⁡ [ 1 + z ] {\displaystyle N=\arg \left[{\frac {G(s)}{1+G(s)}}\right]=\arg[G(s)]-\arg[1+G(s)]=\arg[z]-\arg[1+z]} are given by the points z in the G(s)-plane such that the angle between -1 and z and the angle between 0 and z is constant. In other words, the angle opposed to the line segment between -1 and 0 must be constant. This implies that the points z satisfying this locus condition are arcs of circles, and this locus is known in the context of control systems as N-circles. == Usage == To use the Hall circles, a plot of M and N circles is done over the Nyquist plot of the open-loop transfer function. The points of the intersection between these graphics give the corresponding value of the closed-loop transfer function. Hall circles are also used with the Nichols plot and in this setting, are also known as Nichols chart. Rather than overlaying directly the Hall circles over the Nichols plot, the points of the circles are transferred to a new coordinate system where the ordinate is given by 20 log 10 ⁡ ( | G ( s ) | ) {\displaystyle 20\log _{10}(|G(s)|)} and the abscissa is given by arg ⁡ ( G ( s ) ) {\displaystyle \arg(G(s))} . The advantage of using Nichols chart is that adjusting the gain of the open loop transfer function directly reflects in up and down translation of the Nichols plot in the chart.

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  • Informedia Digital Library

    Informedia Digital Library

    The Informedia Digital Library is an ongoing research program at Carnegie Mellon University to build search engines and information visualization technology for many types of media. The program has carried out research on spoken document retrieval, video information retrieval, video segmentation, face recognition, and cross-language information retrieval. The Lycos search engine was an early product of the Informedia Digital Library Project. The project is led by Howard Wactlar. Researchers on the project have included: Michael Mauldin, Alex Hauptmann, Michael Christel, Michael Witbrock, Raj Reddy, Takeo Kanade and Scott Stevens.

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  • Aidoc

    Aidoc

    Aidoc Medical is an Israeli technology company that develops computer-aided simple triage and notification systems. Aidoc has obtained U.S. Food and Drug Administration and CE mark approval for its stroke, pulmonary embolism, cervical fracture, intracranial hemorrhage, intra-abdominal free gas, and incidental pulmonary embolism algorithms. Aidoc algorithms are in use in more than 900 hospitals and imaging centers, including Montefiore Nyack Hospital, LifeBridge Health, LucidHealth, Yale New Haven Hospital, Cedars-Sinai Medical Center, University of Rochester Medical Center, and Sheba Medical Center. == History == Aidoc was founded in 2016 by Elad Walach as the CEO, Michael Braginsky as the CTO and Guy Reiner as the VP. In April 2017, the company raised $7M, led by TLV Partners, and in April 2019, the company raised another $27M, led by Square Peg capital. There have been several additional rounds of funding as well, bringing Aidoc's total investment to $370M as of July 2025. In August 2018, Aidoc gained FDA clearance for its intracranial hemorrhage system, and in May 2019 it received clearance for the pulmonary embolism system. In January 2020, the system for detecting large-vessel occlusions (LVOs) in head CTA examinations obtained FDA clearance. In October 2024, it was reported that Aidoc is working with NVIDIA to develop a framework for deployment and integration of artificial intelligence tools in healthcare. The Blueprint for Resilient Integration and Deployment of Guided Excellence (BRIDGE) is a guideline to facilitate AI adoption in the healthcare industry. == Products and market == Aidoc has developed a suite of artificial intelligence products that flag both time-sensitive and time-consuming (for the radiologist) abnormalities across the body. The algorithms are developed with large quantities of data to provide diagnostic aid for a broad set of pathologies. The company offers an array of algorithms that span across the body, including for intracranial hemorrhage, spine fractures (C, T & L), free air in the abdomen, pulmonary embolism, and more. It developed "Always-on AI", a term coined by Elad Walach that refers to a type of artificial intelligence that is "Always-on—constantly running in the background and automatically analyzing medical imaging data, identifying urgent findings, and sparing radiologists from "drowning" in vast amounts of irrelevant data. Aidoc's solutions cover medical conditions prevalent in all settings (ED/inpatient/outpatient), including level 1 trauma centers, outpatient imaging centers, teleradiology groups and, are set up in over 200 medical centers worldwide. Notable customers include the University of Rochester Medical Center and Global Diagnostics Australia. Aidoc announced in 2024 that its new Clinical AI Reasoning Engine (CARE1) had been submitted for FDA approval. In September 2025 Aidoc received a "Breakthrough Device Designation" from the FDA for a new multi-triage solution that spans numerous acute findings in CT scans. Aidoc's CARE1 foundation model was the basis of the workflow on which the designation was made, enabling simultaneous coverage of multiple pathologies. This new designation allows parallel FDA review of multiple indications under a single submission. In April 2026, Aidoc raised million in a Series E funding round led by Growth Equity at Goldman Sachs Alternatives, with participation from General Catalyst and NVentures. The financing brought the company's total funding to over million. == Clinical Research == A clinical study on Aidoc’ accuracy of deep convolutional neural networks for the detection of pulmonary embolism (PE) on CT pulmonary angiograms (CTPAs) was performed by the University Hospital of Basel and presented at the European Congress of Radiology, showing that the Aidoc algorithm reached 93% sensitivity and 95% specificity. Clinical research has also been performed to test the diagnostic performance of Aidoc's deep learning-based triage system for the flagging of acute findings in abdominal computed tomography (CT) examinations. Overall, the algorithm achieved 93% sensitivity (91/98, 7 false negatives) and 97% specificity (93/96, 3 false-positive) in the detection of acute abdominal findings. Additional clinical research on Aidoc's Intracranial hemorrhage algorithm accuracy was presented at the European Congress of Radiology by Antwerp University Hospital, evaluating the use of its deep learning algorithm for the detection of intracranial hemorrhage on non-contrast enhanced CT of the brain. The University of Washington completed a study on the accuracy of Aidoc's intracranial hemorrhage algorithm.

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  • Proximal gradient methods for learning

    Proximal gradient methods for learning

    Proximal gradient (forward backward splitting) methods for learning is an area of research in optimization and statistical learning theory which studies algorithms for a general class of convex regularization problems where the regularization penalty may not be differentiable. One such example is ℓ 1 {\displaystyle \ell _{1}} regularization (also known as Lasso) of the form min w ∈ R d 1 n ∑ i = 1 n ( y i − ⟨ w , x i ⟩ ) 2 + λ ‖ w ‖ 1 , where x i ∈ R d and y i ∈ R . {\displaystyle \min _{w\in \mathbb {R} ^{d}}{\frac {1}{n}}\sum _{i=1}^{n}(y_{i}-\langle w,x_{i}\rangle )^{2}+\lambda \|w\|_{1},\quad {\text{ where }}x_{i}\in \mathbb {R} ^{d}{\text{ and }}y_{i}\in \mathbb {R} .} Proximal gradient methods offer a general framework for solving regularization problems from statistical learning theory with penalties that are tailored to a specific problem application. Such customized penalties can help to induce certain structure in problem solutions, such as sparsity (in the case of lasso) or group structure (in the case of group lasso). == Relevant background == Proximal gradient methods are applicable in a wide variety of scenarios for solving convex optimization problems of the form min x ∈ H F ( x ) + R ( x ) , {\displaystyle \min _{x\in {\mathcal {H}}}F(x)+R(x),} where F {\displaystyle F} is convex and differentiable with Lipschitz continuous gradient, R {\displaystyle R} is a convex, lower semicontinuous function which is possibly nondifferentiable, and H {\displaystyle {\mathcal {H}}} is some set, typically a Hilbert space. The usual criterion of x {\displaystyle x} minimizes F ( x ) + R ( x ) {\displaystyle F(x)+R(x)} if and only if ∇ ( F + R ) ( x ) = 0 {\displaystyle \nabla (F+R)(x)=0} in the convex, differentiable setting is now replaced by 0 ∈ ∂ ( F + R ) ( x ) , {\displaystyle 0\in \partial (F+R)(x),} where ∂ φ {\displaystyle \partial \varphi } denotes the subdifferential of a real-valued, convex function φ {\displaystyle \varphi } . Given a convex function φ : H → R {\displaystyle \varphi :{\mathcal {H}}\to \mathbb {R} } an important operator to consider is its proximal operator prox φ : H → H {\displaystyle \operatorname {prox} _{\varphi }:{\mathcal {H}}\to {\mathcal {H}}} defined by prox φ ⁡ ( u ) = arg ⁡ min x ∈ H φ ( x ) + 1 2 ‖ u − x ‖ 2 2 , {\displaystyle \operatorname {prox} _{\varphi }(u)=\operatorname {arg} \min _{x\in {\mathcal {H}}}\varphi (x)+{\frac {1}{2}}\|u-x\|_{2}^{2},} which is well-defined because of the strict convexity of the ℓ 2 {\displaystyle \ell _{2}} norm. The proximal operator can be seen as a generalization of a projection. We see that the proximity operator is important because x ∗ {\displaystyle x^{}} is a minimizer to the problem min x ∈ H F ( x ) + R ( x ) {\displaystyle \min _{x\in {\mathcal {H}}}F(x)+R(x)} if and only if x ∗ = prox γ R ⁡ ( x ∗ − γ ∇ F ( x ∗ ) ) , {\displaystyle x^{}=\operatorname {prox} _{\gamma R}\left(x^{}-\gamma \nabla F(x^{})\right),} where γ > 0 {\displaystyle \gamma >0} is any positive real number. === Moreau decomposition === One important technique related to proximal gradient methods is the Moreau decomposition, which decomposes the identity operator as the sum of two proximity operators. Namely, let φ : X → R {\displaystyle \varphi :{\mathcal {X}}\to \mathbb {R} } be a lower semicontinuous, convex function on a vector space X {\displaystyle {\mathcal {X}}} . We define its Fenchel conjugate φ ∗ : X → R {\displaystyle \varphi ^{}:{\mathcal {X}}\to \mathbb {R} } to be the function φ ∗ ( u ) := sup x ∈ X ⟨ x , u ⟩ − φ ( x ) . {\displaystyle \varphi ^{}(u):=\sup _{x\in {\mathcal {X}}}\langle x,u\rangle -\varphi (x).} The general form of Moreau's decomposition states that for any x ∈ X {\displaystyle x\in {\mathcal {X}}} and any γ > 0 {\displaystyle \gamma >0} that x = prox γ φ ⁡ ( x ) + γ prox φ ∗ / γ ⁡ ( x / γ ) , {\displaystyle x=\operatorname {prox} _{\gamma \varphi }(x)+\gamma \operatorname {prox} _{\varphi ^{}/\gamma }(x/\gamma ),} which for γ = 1 {\displaystyle \gamma =1} implies that x = prox φ ⁡ ( x ) + prox φ ∗ ⁡ ( x ) {\displaystyle x=\operatorname {prox} _{\varphi }(x)+\operatorname {prox} _{\varphi ^{}}(x)} . The Moreau decomposition can be seen to be a generalization of the usual orthogonal decomposition of a vector space, analogous with the fact that proximity operators are generalizations of projections. In certain situations it may be easier to compute the proximity operator for the conjugate φ ∗ {\displaystyle \varphi ^{}} instead of the function φ {\displaystyle \varphi } , and therefore the Moreau decomposition can be applied. This is the case for group lasso. == Lasso regularization == Consider the regularized empirical risk minimization problem with square loss and with the ℓ 1 {\displaystyle \ell _{1}} norm as the regularization penalty: min w ∈ R d 1 n ∑ i = 1 n ( y i − ⟨ w , x i ⟩ ) 2 + λ ‖ w ‖ 1 , {\displaystyle \min _{w\in \mathbb {R} ^{d}}{\frac {1}{n}}\sum _{i=1}^{n}(y_{i}-\langle w,x_{i}\rangle )^{2}+\lambda \|w\|_{1},} where x i ∈ R d and y i ∈ R . {\displaystyle x_{i}\in \mathbb {R} ^{d}{\text{ and }}y_{i}\in \mathbb {R} .} The ℓ 1 {\displaystyle \ell _{1}} regularization problem is sometimes referred to as lasso (least absolute shrinkage and selection operator). Such ℓ 1 {\displaystyle \ell _{1}} regularization problems are interesting because they induce sparse solutions, that is, solutions w {\displaystyle w} to the minimization problem have relatively few nonzero components. Lasso can be seen to be a convex relaxation of the non-convex problem min w ∈ R d 1 n ∑ i = 1 n ( y i − ⟨ w , x i ⟩ ) 2 + λ ‖ w ‖ 0 , {\displaystyle \min _{w\in \mathbb {R} ^{d}}{\frac {1}{n}}\sum _{i=1}^{n}(y_{i}-\langle w,x_{i}\rangle )^{2}+\lambda \|w\|_{0},} where ‖ w ‖ 0 {\displaystyle \|w\|_{0}} denotes the ℓ 0 {\displaystyle \ell _{0}} "norm", which is the number of nonzero entries of the vector w {\displaystyle w} . Sparse solutions are of particular interest in learning theory for interpretability of results: a sparse solution can identify a small number of important factors. === Solving for L1 proximity operator === For simplicity we restrict our attention to the problem where λ = 1 {\displaystyle \lambda =1} . To solve the problem min w ∈ R d 1 n ∑ i = 1 n ( y i − ⟨ w , x i ⟩ ) 2 + ‖ w ‖ 1 , {\displaystyle \min _{w\in \mathbb {R} ^{d}}{\frac {1}{n}}\sum _{i=1}^{n}(y_{i}-\langle w,x_{i}\rangle )^{2}+\|w\|_{1},} we consider our objective function in two parts: a convex, differentiable term F ( w ) = 1 n ∑ i = 1 n ( y i − ⟨ w , x i ⟩ ) 2 {\displaystyle F(w)={\frac {1}{n}}\sum _{i=1}^{n}(y_{i}-\langle w,x_{i}\rangle )^{2}} and a convex function R ( w ) = ‖ w ‖ 1 {\displaystyle R(w)=\|w\|_{1}} . Note that R {\displaystyle R} is not strictly convex. Let us compute the proximity operator for R ( w ) {\displaystyle R(w)} . First we find an alternative characterization of the proximity operator prox R ⁡ ( x ) {\displaystyle \operatorname {prox} _{R}(x)} as follows: u = prox R ⁡ ( x ) ⟺ 0 ∈ ∂ ( R ( u ) + 1 2 ‖ u − x ‖ 2 2 ) ⟺ 0 ∈ ∂ R ( u ) + u − x ⟺ x − u ∈ ∂ R ( u ) . {\displaystyle {\begin{aligned}u=\operatorname {prox} _{R}(x)\iff &0\in \partial \left(R(u)+{\frac {1}{2}}\|u-x\|_{2}^{2}\right)\\\iff &0\in \partial R(u)+u-x\\\iff &x-u\in \partial R(u).\end{aligned}}} For R ( w ) = ‖ w ‖ 1 {\displaystyle R(w)=\|w\|_{1}} it is easy to compute ∂ R ( w ) {\displaystyle \partial R(w)} : the i {\displaystyle i} th entry of ∂ R ( w ) {\displaystyle \partial R(w)} is precisely ∂ | w i | = { 1 , w i > 0 − 1 , w i < 0 [ − 1 , 1 ] , w i = 0. {\displaystyle \partial |w_{i}|={\begin{cases}1,&w_{i}>0\\-1,&w_{i}<0\\\left[-1,1\right],&w_{i}=0.\end{cases}}} Using the recharacterization of the proximity operator given above, for the choice of R ( w ) = ‖ w ‖ 1 {\displaystyle R(w)=\|w\|_{1}} and γ > 0 {\displaystyle \gamma >0} we have that prox γ R ⁡ ( x ) {\displaystyle \operatorname {prox} _{\gamma R}(x)} is defined entrywise by ( prox γ R ⁡ ( x ) ) i = { x i − γ , x i > γ 0 , | x i | ≤ γ x i + γ , x i < − γ , {\displaystyle \left(\operatorname {prox} _{\gamma R}(x)\right)_{i}={\begin{cases}x_{i}-\gamma ,&x_{i}>\gamma \\0,&|x_{i}|\leq \gamma \\x_{i}+\gamma ,&x_{i}<-\gamma ,\end{cases}}} which is known as the soft thresholding operator S γ ( x ) = prox γ ‖ ⋅ ‖ 1 ⁡ ( x ) {\displaystyle S_{\gamma }(x)=\operatorname {prox} _{\gamma \|\cdot \|_{1}}(x)} . === Fixed point iterative schemes === To finally solve the lasso problem we consider the fixed point equation shown earlier: x ∗ = prox γ R ⁡ ( x ∗ − γ ∇ F ( x ∗ ) ) . {\displaystyle x^{}=\operatorname {prox} _{\gamma R}\left(x^{}-\gamma \nabla F(x^{})\right).} Given that we have computed the form of the proximity operator explicitly, then we can define a standard fixed point iteration procedure. Namely, fix some initial w 0 ∈ R d {\displaystyle w^{0}\in \mathbb {R} ^{d}} , and for k = 1 , 2 , … {\displaystyle k=1,2,\ldots } define w k + 1 = S γ ( w k − γ ∇ F ( w k ) ) . {\displaystyle w^{k+1}=S_{\gamma }\left(w^{k}-\gamma \nabla F\l

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  • Vinelink.com

    Vinelink.com

    Vinelink.com (VINE) is a national website in the United States that allows victims of crime, and the general public, to track the movements of prisoners held by the various states and territories. The first four letters in the websites name, "vine", are an acronym for "Victim Information and Notification Everyday". Vinelink.com displays information, based on the information provided by the various states' departments of correction and other law enforcement agencies, on whether an inmate is in custody, has been released, has been granted parole or probation, or has escaped from custody. In some cases, the website will reveal whether a defendant has been granted parole or probation, but then subsequently violated conditions of their release and become a fugitive. Information provided on Vinelink.com represents metadata, in that the website lists a defendant's custody status; but does not list what the individual is charged with, their criminal history, or the amount of their bail, if applicable. Internet users accessing the Vinelink.com website choose from a map of states and provinces within the United States where they wish to perform a search for an inmate. The user may then search for an individual using the inmate's or parolee's name, or by entering the inmate's specific department of corrections inmate number, if known. When the inmate's custody status changes, users who have registered to be notified of such changes will be notified via email, phone or both. This information is currently released upon request, without the website requesting reasons for the users search or requiring payment, as public records available to the general public. Inmate information is available for most states, and for Puerto Rico, on the website. The states of Arizona, Georgia, Massachusetts, Montana, New Hampshire and West Virginia provide very limited information on the site. In March of 2025, The Maine Sheriff's Association entered into a contract to pilot the use of the VINE system in three counties in the state as well as a regional jail, therefore making South Dakota the only state that does not participate in the VINE system to any degree. The website does not provide data on prisoners detained by the Federal Bureau of Prisons which has its own inmate locator web site nor for inmates of the U.S. military prisons.

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  • Informedia Digital Library

    Informedia Digital Library

    The Informedia Digital Library is an ongoing research program at Carnegie Mellon University to build search engines and information visualization technology for many types of media. The program has carried out research on spoken document retrieval, video information retrieval, video segmentation, face recognition, and cross-language information retrieval. The Lycos search engine was an early product of the Informedia Digital Library Project. The project is led by Howard Wactlar. Researchers on the project have included: Michael Mauldin, Alex Hauptmann, Michael Christel, Michael Witbrock, Raj Reddy, Takeo Kanade and Scott Stevens.

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