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Adobe InDesign

Adobe InDesign is a desktop publishing and page layout designing software application produced by Adobe and first released in 1999. It can be used to create works such as posters, flyers, brochures, magazines, newspapers, presentations, books and ebooks. InDesign can also publish content suitable for tablet devices in conjunction with Adobe Digital Publishing Suite. Graphic designers and production artists are the principal users. InDesign is the successor to PageMaker, which Adobe acquired by buying Aldus Corporation in late 1994. (Freehand, Aldus's competitor to Adobe Illustrator, was licensed from Altsys, the maker of Fontographer.) By 1998, PageMaker had lost much of the professional market to the comparatively feature-rich QuarkXPress version 3.3, released in 1992, and version 4.0, released in 1996. In 1999, Quark announced its offer to buy Adobe and to divest the combined company of PageMaker to avoid problems under United States antitrust law. Adobe declined Quark's offer and continued to develop a new desktop publishing application. Aldus had begun developing a successor to PageMaker, code-named "Shuksan". Later, Adobe code-named the project "K2", and Adobe released InDesign 1.0 in 1999. InDesign exports documents in Adobe's Portable Document Format (PDF) and supports multiple languages. It was the first DTP application to support Unicode character sets, advanced typography with OpenType fonts, advanced transparency features, layout styles, optical margin alignment, and cross-platform scripting with JavaScript. Later versions of the software introduced new file formats. To support the new features, especially typography, introduced with InDesign CS, the program and its document format are not backward-compatible. Instead, InDesign CS2 introduced the INX (.inx) format, an XML-based document representation, to allow backward compatibility with future versions. InDesign CS versions updated with the 3.1 April 2005 update can read InDesign CS2-saved files exported to the .inx format. The InDesign Interchange format does not support versions earlier than InDesign CS. With InDesign CS4, Adobe replaced INX with InDesign Markup Language (IDML), another XML-based document representation. InDesign was the first native Mac OS X publishing software. With the third major version, InDesign CS, Adobe increased InDesign's distribution by bundling it with Adobe Photoshop, Adobe Illustrator, and Adobe Acrobat in Adobe Creative Suite. Adobe developed InDesign CS3 (and Creative Suite 3) as universal binary software compatible with native Intel and PowerPC Macs in 2007, two years after the announced 2005 schedule, inconveniencing early adopters of Intel-based Macs. Adobe CEO Bruce Chizen said, "Adobe will be first with a complete line of universal applications." == File format == The MIME type is not official File Open formats: indd, indl, indt, indb, inx, idml, pmd, xqx New File formats: indd, indl, indb File Save As formats: indd, indt Save file format for InCopy: icma (Assignment file) icml (Content file, Exported file) icap (Package for InCopy) idap (Package for InDesign) File Export formats: pdf, idml, icml, eps, jpg, txt, XML, rtf == Versions == Newer versions can, as a rule, open files created by older versions, but the reverse is not true. Current versions can export the InDesign file as an IDML file (InDesign Markup Language), which can be opened by InDesign versions from CS4 upwards; older versions from CS4 down can export to an INX file (InDesign Interchange format). === Server version === In October 2005, Adobe released InDesign Server CS2, a modified version of InDesign (without a user interface) for Windows and Macintosh server platforms. It does not provide any editing client; rather, it is for use by developers in creating client-server solutions with the InDesign plug-in technology. In March 2007 Adobe officially announced Adobe InDesign CS3 Server as part of the Adobe InDesign family. == Features == Paragraph styles are an essential tool for designers when working with text in Adobe InDesign. Despite their menacing appearance, they are straightforward to operate. Other features that make InDesign a good tool for working with text and paragraphs include: Creating frames and shapes Aligning objects with grids and guides Manipulating objects Organizing objects Importing text Formatting text Spell checking Importing images Parent pages (formerly master pages) Paragraph styles == Internationalization and localization == InDesign Middle Eastern editions have unique settings for laying out Arabic or Hebrew text. They feature: Text settings: Special settings for laying out Arabic or Hebrew text, such as: Ability to use Arabic, Persian or Hindi digits; Use kashidas for letter spacing and full justification; Ligature option; Adjust the position of diacritics, such as vowels of the Arabic script; Justify text in three possible ways: Standard, Arabic, Naskh; Option to insert special characters, including Geresh, Gershayim, Maqaf for Hebrew and Kashida for Arabic texts; Apply standard, Arabic, or Hebrew styles for page, paragraph, and footnote numbering. Bi-directional text flow: Right-to-left behavior applies to several objects: Story, paragraph, character, and table. It allows mixing right-to-left and left-to-right words, paragraphs, and stories in a document. Changing the direction of neutral characters (e.g., / or ?) is possible according to the user's keyboard language. Table of contents: Provides a table of contents titles, one for each supported language. This table is sorted according to the chosen language. InDesign CS4 Middle Eastern versions allow users to select the language of the index title and cross-references. Indices: This allows the creation of a simple keyword index or a somewhat more detailed index of the information in the text using embedded indexing codes. Unlike more sophisticated programs, InDesign cannot insert character style information as part of an index entry (e.g., when indexing book, journal, or movie titles). Indices are limited to four levels (the top level and three sub-levels). Like tables of contents, indices can be sorted according to the selected language. Importing and exporting: Can import QuarkXPress files up to version 4.1 (1999), even using Arabic XT, Arabic Phonyx, or Hebrew XPressWay fonts, retaining the layout and content. Includes 50 import/export filters, including a Microsoft Word 97-98-2000 import filter and a plain text import filter. Exports IDML files can be read by QuarkXPress 2017. Reverse layout: Include a reverse layout feature to reverse the layout of a document when converting a left-to-right document to a right-to-left one or vice versa. Complex script rendering: InDesign supports Unicode character encoding, and Middle Eastern editions support complex text layouts for Arabic and Hebrew complex scripts. The underlying Arabic and Hebrew support is present in the Western editions of InDesign CS4, CS5, CS5.5, and CS6, but the user interface is not exposed, making it difficult to access.
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GNU social

GNU social (and its predecessor StatusNet) is a largely defunct free and open-source microblogging social networking service that implements the OStatus and ActivityPub standards for interoperability between installations. While offering similar functionality to social networks such as Twitter, GNU social seeks to provide the ability for open and federated communication between different microblogging communities, known as 'instances'. Both enterprises and individuals can install and control their own instances and user data. At its peak in popularity, GNU social had been deployed on hundreds of interconnected instances, however has since fallen into disuse as competing software like Mastodon and Pleroma have taken its position as the dominant federated microblogging services. Later on in its lifespan, the project split into two separate branches, with "v2" being a continuation of the original codebase for maintenance of existing instances, with "v3" being a complete redesign of the project meant to integrate further ActivityPub support and modernization of the user experience and its technological back-end. As of August 15, 2022, there had been no new commits to the v2 branch, with the v3 branch also no longer being actively developed not long after by November 25, 2022, with the project essentially abandoned. Despite its modern obsolescence and dated design compared to modern platforms, GNU social and StatusNet is regarded to be the origin of the Fediverse network and has had a major influence on the design of more modern decentralized social networks that succeeded it. == History == While being the main project within its lineage, GNU social originally began as a fork of StatusNet. The software was first developed for a service called identi.ca from Evan Prodromou, which offered free microblogging accounts to the public. The software quickly became one of the first popular examples of a decentralized social network, as identi.ca allowed any other server that was running the software to communicate with it, something which had not previously been attempted before in social media at such a large scale. === StatusNet === Originally, StatusNet (named Laconica at the time) was launched with a communication protocol designed specifically for the project called OpenMicroBlogging (OMB). With version 0.8.1, the name of the software was changed to StatusNet. Version 0.9.0 was released soon after in March 3, 2010, with the developers implementing a newly designed protocol dubbed OStatus, with support for OMB being dropped not long after. Compared to OpenMicroBlogging, OStatus could handle and federate more events and actions than the basic plaintext communication that OMB provided and was based on a variety of other web technologies, allowing for easier adoption of new implementations of the protocol for servers and clients compared to the fully custom architecture of OMB. With the StatusNet name change, the company developing both the software and OStatus as well as managing identi.ca rebranded from Control Yourself to StatusNet Inc. In August 2010, the company raised a new round of venture capital funds to establish a hosting service under the status.net domain from sources such as First Mark Capital, BOLDstart Ventures, iNovia Capital and Montreal Start Up, raising over $2.3 million in funding up to that point. The hosting service allowed anyone to establish their own StatusNet instance without maintaining a server, similar to WordPress.com and other blogging platforms. New registrations on identi.ca along with the ability to create new status.net instances was disabled in December 2012, in preparation for a migration to pump.io that has since been named by users of StatusNet and OStatus as "the Pumpocalypse". pump.io was a brand new software package like StatusNet, but with a new protocol designed for general purpose activity streams outside of microblogging and ease-of-use for developers building on the technology, much like the transition from OMB to OStatus. The announcement was seen as unexpected among identi.ca users, who were concerned about the possibility of their statuses being deleted with the transition. At the same time, server administrators running third-party instances and their users who were left behind on StatusNet were also worried, as it was unclear at the time whether future development of the software would be picked up by a new maintainer. The transition for identi.ca users to pump.io was completed on 12 July 2013. ==== Previous names ==== The original name of StatusNet was Laconica, a reference to the Laconic phrase; a particularly brief statement commonly attributed to the leaders of Sparta (Laconia being the Greek region containing Sparta). In microblogging, all messages are designed to be very short due to the traditional 140-character limit on message size, a limitation imported from SMS. Beginning with version 0.8.1, the name was changed to StatusNet. The developers said that the new name "simply reflects what our software does: send status updates into your social network." === GNU social === GNU social originally began as a side project of GNU FM (Libre.fm) maintainer Matt Lee, with the goal of being able to federate messages between Last.fm and other instances of GNU FM using StatusNet plugins. Around the same time, a developer named Mikael Nordfeldth forked StatusNet with the intention of maintaining it as a personal project, dubbing it "Free Social". However, following identi.ca's transition to pump.io and its developers' sudden abandonment of StatusNet, the projects received more attention from server administrators and other users looking for an actively updated alternative. Shortly after LibrePlanet 2012, a plan was formed to merge all three projects into a single service. On June 8, 2013, it was announced that along with Free Social, StatusNet would be merged into the GNU social project and stewarded by the Free Software Foundation, with the project since becoming the dominant variant of StatusNet. During GNU social's lifespan, a popular theme for the user interface named Quitter was used, which was similar to an earlier Twitter interface. Many instances were made specifically using the name Quitter such as Quitter.se, an instance created by the developer of the theme. Before the establishment of Mastodon's popularity and dominance within the network, Quitter was noted as a frequent location for users of Twitter to migrate to when users disagreed with moderation policies or feature updates, such as when an algorithmic feed was added to Twitter. A fork of GNU social was made called postActiv, which planned to rewrite the backend and user interface of GNU social, as well as to add compatibility for Diaspora's protocol. == Features == A basic GNU social instance takes the form of a microblogging service with a reverse chronological timeline that features status updates and small messages from followed accounts, similar to other services such as Twitter or Weibo. While users could see their own customized timeline, they could access another timeline that showcased every message that the instance knows of, including from other instances that were connected to each other if someone on the instance followed an account from it. Users could also create and join groups, which allows for discussion and collaboration on specific topics. Administrators can also customize their server via the plugin system, which allows developers to create new features or modify existing plugins to suit the needs of the instance via PHP. A notable plugin built for GNU social was Quitter, a revamp of the user interface that resembles an earlier version of Twitter's user interface.
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Software bot

A software bot is a type of software agent in the service of software project management and software engineering. A software bot has an identity and potentially personified aspects in order to serve their stakeholders. Software bots often compose software services and provide an alternative user interface, which is sometimes, but not necessarily conversational. Software bots are typically used to execute tasks, suggest actions, engage in dialogue, and promote social and cultural aspects of a software project. The term bot is derived from robot. However, robots act in the physical world and software bots act only in digital spaces. Some software bots are designed and behave as chatbots, but not all chatbots are software bots. Discussions about the past and future of software bots show that software bots have been adopted for many years. == Usage == Software bots are used to support development activities, such as communication among software developers and automation of repetitive tasks. Software bots have been adopted by several communities related to software development, such as open-source communities on GitHub and Stack Overflow. GitHub bots have user accounts and can open, close, or comment on pull requests and issues. GitHub bots have been used to assign reviewers, ask contributors to sign the Contributor License Agreement, report continuous integration failures, review code and pull requests, welcome newcomers, run automated tests, merge pull requests, fix bugs and vulnerabilities, etc. The Slack tool includes an API for developing software bots. There are slack bots for keeping track of todo lists, coordinating standup meetings, and managing support tickets. The ChatBot company products further simplify the process of creating a custom Slack bot. On Wikipedia, Wikipedia bots automate a variety of tasks, such as creating stub articles, consistently updating the format of multiple articles, and so on. Bots like ClueBot NG are capable of recognizing vandalism and automatically remove disruptive content. == Taxonomies and Classification Frameworks == Lebeuf et al. provide a faceted taxonomy to characterize bots based on a literature review. It is composed of 3 main facets: (i) properties of the environment that the bot was created in; (ii) intrinsic properties of the bot itself; and (iii) the bot's interactions within its environment. They further detail the facets into sets of sub-facets under each of the main facets. Paikari and van der Hoek defined a set of dimensions to enable comparison of software bots, applied specifically to chatbots. It resulted in six dimensions: Type: the main purpose of the bot (information, collaboration, or automation) Direction of the "conversation" (input, output, or bi-directional) Guidance (human-mediated, or autonomous) Predictability (deterministic, or evolving) Interaction style (dull, alternate vocabulary, relationship-builder, human-like) Communication channel (text, voice, or both) Erlenhov et al. raised the question of the difference between a bot and simple automation, since much research done in the name of software bots uses the term bot to describe various different tools and sometimes things are "just" plain old development tools. After interviewing and surveying over 100 developers the authors found that not one, but three definitions dominated the community. They created three personas based on these definitions and the difference between what the three personas see as being a bot is mainly the association with a different set of human-like traits. The chat bot persona (Charlie) primarily thinks of bots as tools that communicates with the developer through a natural language interface (typically voice or chat), and caring little about what tasks the bot is used for or how it actually implements these tasks. The autonomous bot persona (Alex) thinks of bots as tools that work on their own (without requiring much input from a developer) on a task that would normally be done by a human. The smart bot persona (Sam) separates bots and plain old development tools through how smart (technically sophisticated) a tool is. Sam cares less about how the tool communicates, but more about if it is unusually good or adaptive at executing a task. The authors recommends that people doing research or writing about bots try to put their work in the context of one of the personas since the personas have different expectations and problems with the tools. == Example of notable bots == Dependabot and Renovatebot update software dependencies and detect vulnerabilities. (https://dependabot.com/) Probot is an organization that create and maintain bots for GitHub. The example bots using Probot are the following. Auto Assign (https://probot.github.io/apps/auto-assign/) license bot (https://probot.github.io/) Sentiment bot (https://probot.github.io/apps/sentiment-bot/) Untrivializer bot (https://probot.github.io/apps/untrivializer/) Refactoring-Bot (Refactoring-Bot): provides refactoring based on static code analysis Looks good to me bot (LGTM) is a Semmle product that inspects pull requests on GitHub for code style and unsafe code practices. == Issues and threats == Software bots may not be well accepted by humans. A study from the University of Antwerp has compared how developers active on Stack Overflow perceive answers generated by software bots. They find that developers perceive the quality of software bot-generated answers to be significantly worse if the identity of the software bot is made apparent. By contrast, answers from software bots with human-like identity were better received. In practice, when software bots are used on platforms like GitHub or Wikipedia, their username makes it clear that they are bots, e.g., DependaBot, RenovateBot, DatBot, SineBot. Bots may be subject to special rules. For instance, the GitHub terms of service does not allow 'bots' but accepts 'machine account', where a 'machine account' has two properties: 1) a human takes full responsibility of the bot's actions 2) it cannot create other accounts.
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Software construction

Software construction is the process of creating working software via coding and integration. The process includes unit and integration testing although does not include higher level testing such as system testing. Construction is an aspect of the software development lifecycle and is integrated in the various software development process models with varying focus on construction as an activity separate from other activities. In the waterfall model, a software development effort consists of sequential phases including requirements analysis, design, and planning which are prerequisites for starting construction. In an iterative model such as scrum, evolutionary prototyping, or extreme programming, construction as an activity that occurs concurrently or overlapping other activities. Construction planning may include defining the order in which components are created and integrated, the software quality management processes, and the allocation of tasks to teams and developers. To facilitate project management, numerous construction aspects can be measured; these include the amount of code developed, modified, reused, and destroyed, code complexity, code inspection statistics, faults-fixed and faults-found rates, and effort expended. These measurements can be useful for aspects such as ensuring quality and improving the process. == Activities == Construction includes many activities. === Coding === The following are a few of the key aspects of the coding activity: Naming Choice of name for each identifier. One study showed that the effort required to debug a program is minimized when variable names are between 10 and 16 characters. Logic Organization into statements and routines Highly cohesive routines proved to be less error prone than routines with lower cohesion. A study of 450 routines found that 50 percent of the highly cohesive routines were fault free compared to only 18 percent of routines with low cohesion. Another study of a different 450 routines found that routines with the highest coupling-to-cohesion ratios had 7 times as many errors as those with the lowest coupling-to-cohesion ratios and were 20 times as costly to fix. Although studies showed inconclusive results regarding the correlation between routine sizes and the rate of errors in them, but one study found that routines with fewer than 143 lines of code were 2.4 times less expensive to fix than larger routines. Another study showed that the code needed to be changed least when routines averaged 100 to 150 lines of code. Another study found that structural complexity and amount of data in a routine were correlated with errors regardless of its size. Interfaces between routines are some of the most error-prone areas of a program. One study showed that 39 percent of all errors were errors in communication between routines. Unused parameters are correlated with an increased error rate. In one study, only 17 to 29 percent of routines with more than one unreferenced variable had no errors, compared to 46 percent in routines with no unused variables. The number of parameters of a routine should be 7 at maximum as research has found that people generally cannot keep track of more than about seven chunks of information at once. One experiment showed that designs which access arrays sequentially, rather than randomly, result in fewer variables and fewer variable references. One experiment found that loops-with-exit are more comprehensible than other kinds of loops. Regarding the level of nesting in loops and conditionals, studies have shown that programmers have difficulty comprehending more than three levels of nesting. Control flow complexity has been shown to correlate with low reliability and frequent errors. Modularity Structuring and refactoring the code into classes, packages and other structures. When considering containment, the maximum number of data members in a class shouldn't exceed 7±2. Research has shown that this number is the number of discrete items a person can remember while performing other tasks. When considering inheritance, the number of levels in the inheritance tree should be limited. Deep inheritance trees have been found to be significantly associated with increased fault rates. When considering the number of routines in a class, it should be kept as small as possible. A study on C++ programs has found an association between the number of routines and the number of faults. A study by NASA showed that the putting the code into well-factored classes can double the code reusability compared to the code developed using functional design. Error handling Encoding logic to handle both planned and unplanned errors and exceptions. Resource management Managing computational resource use via exclusion mechanisms and discipline in accessing serially reusable resources, including threads or database locks. Security Prevention of code-level security breaches such as buffer overrun and array index overflow. Optimization Optimization while avoiding premature optimization. Documentation Both embedded in the code as comments and as external documents. === Integration === Integration is about combining separately constructed parts. Concerns include planning the sequence in which components will be integrated, creating scaffolding to support interim versions of the software, determining the degree of testing and quality work performed on components before they are integrated, and determining points in the project at which interim versions are tested. === Testing === Testing can reduce the time between when faulty logic is inserted in the code and when it is detected. In some cases, testing is performed after code has been written, but in test-first programming, test cases are created before code is written. Construction includes at least two forms of testing, often performed by the developer who wrote the code: unit testing and integration testing. === Reuse === Software reuse entails more than creating and using libraries. It requires formalizing the practice of reuse by integrating reuse processes and activities into the software life cycle. The tasks related to reuse in software construction during coding and testing may include: selection of the reusable code, evaluation of code or test re-usability, reporting reuse metrics. === Quality assurance === Techniques for ensuring quality as software is constructed include: Testing One study found that the average defect detection rates of Unit testing and integration testing are 30% and 35% respectively. Software inspection With respect to software inspection, one study found that the average defect detection rate of formal code inspections is 60%. Regarding the cost of finding defects, a study found that code reading detected 80% more faults per hour than testing. Another study shown that it costs six times more to detect design defects by using testing than by using inspections. A study by IBM showed that only 3.5 hours were needed to find a defect through code inspections versus 15–25 hours through testing. Microsoft has found that it takes 3 hours to find and fix a defect by using code inspections and 12 hours to find and fix a defect by using testing. In a 700 thousand lines program, it was reported that code reviews were several times as cost-effective as testing. Studies found that inspections result in 20% - 30% fewer defects per 1000 lines of code than less formal review practices and that they increase productivity by about 20%. Formal inspections will usually take 10% - 15% of the project budget and will reduce overall project cost. Researchers found that having more than 2 - 3 reviewers on a formal inspection doesn't increase the number of defects found, although the results seem to vary depending on the kind of material being inspected. Technical review With respect to technical review, one study found that the average defect detection rates of informal code reviews and desk checking are 25% and 40% respectively. Walkthroughs were found to have a defect detection rate of 20% - 40%, but were found also to be expensive especially when project pressures increase. Code reading was found by NASA to detect 3.3 defects per hour of effort versus 1.8 defects per hour for testing. It also finds 20% - 60% more errors over the life of the project than different kinds of testing. A study of 13 reviews about review meetings, found that 90% of the defects were found in preparation for the review meeting while only around 10% were found during the meeting. Static analysis With respect to Static analysis (IEEE1028), studies have shown that a combination of these techniques needs to be used to achieve a high defect detection rate. Other studies showed that different people tend to find different defects. One study found that the extreme programming practices of pair programming, desk checking, unit testing, integration testing, and regression testing can achieve a 90% defect detection rate. An experiment involving exper
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Autonomous things

Autonomous things, abbreviated AuT, or the Internet of autonomous things, abbreviated as IoAT, is an emerging term for the technological developments that are expected to bring computers into the physical environment as autonomous entities without human direction, freely moving and interacting with humans and other objects. Self-navigating drones are the first AuT technology in (limited) deployment. It is expected that the first mass-deployment of AuT technologies will be the autonomous car, generally expected to be available around 2020. Other currently expected AuT technologies include home robotics (e.g., machines that provide care for the elderly, infirm or young), and military robots (air, land or sea autonomous machines with information-collection or target-attack capabilities). AuT technologies share many common traits, which justify the common notation. They are all based on recent breakthroughs in the domains of (deep) machine learning and artificial intelligence. They all require extensive and prompt regulatory developments to specify the requirements from them and to license and manage their deployment (see the further reading below). And they all require unprecedented levels of safety (e.g., automobile safety) and security, to overcome concerns about the potential negative impact of the new technology. As an example, the autonomous car both addresses the main existing safety issues and creates new issues. It is expected to be much safer than existing vehicles, by eliminating the single most dangerous element – the driver. The US's National Highway Traffic Safety Administration estimates 94 percent of US accidents were the result of human error and poor decision-making, including speeding and impaired driving, and the Center for Internet and Society at Stanford Law School claims that "Some ninety percent of motor vehicle crashes are caused at least in part by human error". So while safety standards like the ISO 26262 specify the required safety, there is still a burden on the industry to demonstrate acceptable safety. While car accidents claim every year 35,000 lives in the US, and 1.25 million worldwide, some believe that even "a car that's 10 times as safe, which means 3,500 people die on the roads each year [in the US alone]" would not be accepted by the public. The acceptable level may be closer to the current figures on aviation accidents and incidents, with under a thousand worldwide deaths in most years – three orders of magnitude lower than cars. This underscores the unprecedented nature of the safety requirements that will need to be met for cars, with similar levels of safety expected for other Autonomous Things.
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Mentimeter

Mentimeter (or Menti for short) is a Swedish company based in Stockholm that develops and maintains an eponymous app used to create presentations with real-time feedback. == Foundation and background == Based in Stockholm, Sweden, the Mentimeter app was started by Swedish entrepreneur Johnny Warström and Niklas Ingvar as a response to unproductive meetings. The initial start-up budget was $500,000 raised by a group of prominent investors, including Per Appelgren in 2014, following the market's tendency to invest in Scandinavia. The app also focuses on online collaboration for the education sector, allowing students or public members to answer questions anonymously. The app enables users to share knowledge and real-time feedback on mobile devices with presentations, polls or brainstorming sessions in classes, meetings, gatherings, conferences and other group activities. == Achievements == By 2021, Mentimeter had over 270 million users and was one of Sweden's fastest-growing startups. The company also ranked #10 on 20 Fastest Growing 500 Startups Batch 16 Companies. It was ranked Stockholm's fastest growing company of the 2018 edition of the DI Gasell Award. Mentimeter has a freemium business model.
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Cryptee

Cryptee is a privacy focused client-side encrypted and cross-platform productivity suite and data storage service. == History == Cryptee was founded in 2017, by John Ozbay, a cybersecurity researcher, commenter, and activist, to exclusively focus on providing a secure document editing service similar to Google Docs and Photos for everyone, with a particular focus on victims and survivors of domestic abuse, journalists and reporters. == Software == Users can write personal documents, notes, journals, store images, videos, and various kinds of other files. The source code of Cryptee is open source and publicly available to allow anyone to audit the service with ease, and help identify errors or potential vulnerabilities in a public and transparent manner. Cryptee has a few key features that differentiate it from other services in the industry, such as its Ghost Folders and Ghost Albums features, built specifically with victims and survivors of domestic abuse, journalists and reporters in mind. Cryptee allows users to hide (ghost) folders for plausible deniability also as known as deniable encryption in the field of cryptography and steganography, and ensure privacy even under coercion. === Features === Cryptee Docs' features include: To-do lists, Markdown support, KaTeX math and file attachments. cross-platform accessible, as it is a progressive web app. Bulk transfer from other note taking apps such as Evernote. Encrypted PDF and print-accurate (A4 and U.S. Letter paper-sized) text editing. Ability to edit docx files Cryptee Photos' features include: Ability to create slideshows. Ability to store original quality of photos. Ability to tag photos for organization. === Commercial strategy === The company's commercial strategy is focused on offering to its users an open source and transparent Photo Storage, Document Editor and Cloud Storage services without trackers or advertisements as it seeks to compete with Google Docs, Google Photos and similar services through its offerings. === Privacy === Cryptee utilizes zero-access storage to safe-keep all users' sensitive digital belongings. == Advocacy == === Lockdown mode === In July 2022, to fortify iPhones against the Pegasus Spyware, Apple announced a new, upcoming Lockdown Mode feature in iOS 16, welcomed by many experts. In the following weeks after Apple's announcement, in August 2022, the Founder and CEO of Cryptee, and privacy activist John Ozbay published their research detailing shortcoming of Apple's Lockdown Mode. They demonstrated that enabling Lockdown Mode makes it possible for all websites and online ads to be able to detect if users have Lockdown Mode enabled or not. This was due to the fact that disabling web fonts (an attack surface) was detectable by websites. === Confrontations against Apple === ==== On PWAs ==== In February 2024, Apple announced plans to kill progressive web apps on iOS devices in the EU, claiming it was to comply with the Digital Markets Act (DMA). The announcement was criticized as anti-competitive by many in the tech industry, including by Tim Sweeney, the CEO of Epic Games. In response, Cryptee started working together with Open Web Advocacy (OWA), an international not-for-profit digital rights group to advocate for the future of the open web, promote web browser choice on mobile operating systems through challenging Apple's anti-competitive third party browser engine ban, and to champion the use and equality of progressive web apps over native apps, by reaching out to the European Union's Digital Markets Act (DMA) team. To better understand the consequences of Apple's decision to kill web apps, the EU announced that they "seek to investigate Apple over cutting off web apps", and that they sent "requests for information to Apple and to app developers, who can provide useful information for our assessment". Apart from sending a response to the EU, Cryptee, along with the OWA, launched an open letter to Tim Cook, which in 48 hours, got thousands of signatories including European Parliament Members Karen Melchior and Patrick Breyer; and thousands of other developers and organizations from over 100 countries. Consequently, 24 hours later, Apple backed off, and reversed course on its plan to cut off progressive web apps in the EU. ==== Ozbay's representations ==== Following the events, eventually on March 18, 2024, Founder and CEO of Cryptee John Ozbay represented the Open Web Advocacy group in European Union's Digital Markets Act (DMA) hearing for Apple. At the hearing, OWA confronted Apple, accused Apple of "maliciously intending to undermine user choice", and stated that there was no defense for Apple's behavior. In response, according to the tech news outlet Ars Technica, Apple's spokesperson "seemed to dodge Ozbay's question". ==== Cooperation with the EU ==== Within a week of the hearing, the European Union announced a DMA non-compliance investigation against Apple and United States' Department of Justice filed an antitrust lawsuit against Apple. A few months later, on June 27, 2024, Cryptee, in cooperation with EDRi — an international advocacy group, along with Article 19 — a British international human rights organization, Privacy International, F-Droid, Free Software Foundation Europe, Guardian Project and others have submitted a comprehensive analysis to the European Commission about how Apple's plans to comply with the Digital Markets Act are insufficient. == Reviews == In a 2018 article, Wall Street Journal's MarketWatch reviewed Cryptee, articulating the fact that Cryptee offers zero-access storage for photos, files, documents and notes, and pointed out that: "Being based in Estonia puts Cryptee outside the “14 eyes jurisdiction,” an international surveillance alliance of European Union and North American countries, making it less likely it will be targeted with demands for data". In addition, the review highlighted Cryptee's Ghost Folders feature which ensures privacy even under coercion. In a 2019 article, Reclaim The Net named Cryptee as one of the "5 great privacy-focused Evernote alternatives to keep your notes safe", underlining that: "When it comes to security, this app is state of the art." and that "When making this app, the developers thought about every aspect of security and have taken every precaution to make it as secure as possible.". The review further underscored Cryptee's open-source nature, its strong encryption, and easy migration features. In a 2021 article, The Verge reviewed Cryptee, pointing out that Cryptee, based out of Europe, is one of the main photo storage service alternatives to Google Photos, and that it's their recommendation for users who are "concerned about privacy and like the idea of encryption" as Cryptee "offers to keep all your photos encrypted using AES-256". In a 2024 article, Beebom, enlisted Cryptee as one of the "7 best iCloud Photos Alternatives for iPhone and iPad", complimenting Cryptee's simplicity, its use of encryption to safeguard users' photos against hacking by not storing any unencrypted data. The article also provided further attention to Cryptee's additional features such as such as Ghost Albums, slideshows, easy-to-use drag and drop uploads, tagging and users' ability to store original-quality photos on Cryptee, concluding that Cryptee is "a safe bet if you are on the lookout for a privacy-centric iCloud Photos alternative".
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AirPair

AirPair is a service and eponymous company that connects people who need help with programming issues (usually, programmers at small technology companies or at finance companies that use technology products) and people who can help them. Unlike services such as oDesk and Elance, AirPair is not a service for outsourcing programming tasks, but rather a service that facilitates one-off knowledge transfers from people with highly specialized knowledge of particular technology stacks or programming issues to people who are in need of specialized help. == History == AirPair launched in March 2013, with founder Jonathon Kresner, who hails from Australia, working full-time, and it soon hired three other part-time developers to work alongside him. Kresner had previously founded two other startups: Preparty, a social invitation and event-booking service based in Australia, and ClimbFind, an online rock-climbing community that reached a million users. Kresner was inspired to work on AirPair because he saw the need for outside expert assistance with programming issues arise regularly at these startups. In November 2013, founder Kresner describes the company's initial success at bootstrapping itself to "Ramen profitability" in a blog post. In December 2013, AirPair was accepted into the Winter 2014 Y Combinator batch. In March 2014, AirPair announced it would launch partnerships with Stripe, Twilio, and other companies that had their own application programming interfaces, allowing developers having trouble with the APIs to seek help over AirPair from experts on the APIs. AirPair presented at the Y Combinator Winter 2014 Demo Day on March 25, 2014, and successfully raised over $1 million within the next 48 hours. == Reception == A review of AirPair by Will Lam stressed that because payment was based on time rather than results, it was important to use it for clearly thought-out questions where one had high confidence that the session would help. Dennis Beatty, who met AirPair founder Jonathon Kresner in March 2014, wrote in April 2014 a glowing review of AirPair's vision of connecting people and its business success. AirPair has been compared with other peer-to-peer coding help sites such as Codementor and HackHands.
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Himmat (app)

Himmat is a women's safety mobile application of Delhi Police. It was launched by Home Minister Rajnath Singh on 1 January 2015. The app is freely available for Android mobile phones and can be downloaded from Delhi Police website. Delhi Police plans to launch app for other platforms in future. Low registrations and other problems resulted in a parliamentary panel calling the app a failure in 2018. Himmat has gone on to be called as one of India's best safety apps for women.
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Outlook on the web

Outlook on the web (formerly Outlook Web App and Outlook Web Access) is a personal information manager web app from Microsoft. It is a web-based version of Microsoft Outlook, and is included in Exchange Server and Exchange Online (a component of Microsoft 365). It can be freely accessed from any web browser whether inside or outside an organization's network, and includes a web email client, a calendar tool, a contact manager, and a task manager. It also includes add-in integration, Skype on the web, and alerts as well as unified themes that span across all the web apps. == Purpose == Outlook on the web is available to Microsoft 365 (formerly Office 365) and Exchange Online subscribers, and is included with the on-premises Exchange Server, to enable users to connect to their email accounts via a web browser, without requiring the installation of Microsoft Outlook or other email clients. In case of Exchange Server, it is hosted on a local intranet and requires a network connection to the Exchange Server for users to work with e-mail, address book, calendars and task. The Exchange Online version, which can be bought either independently or through Office 365 licensing program, is hosted on Microsoft servers on the World Wide Web. == History == Outlook Web Access was created in 1995 by Microsoft Program Manager Thom McCann on the Exchange Server team. An early working version was demonstrated by Microsoft Vice President Paul Maritz at Microsoft's famous Internet summit in Seattle on December 27, 1995. The first customer version was shipped as part of the Exchange Server 5.0 release in early 1997. The first component to allow client-side scripts to issue HTTP requests (XMLHTTP) was originally written by the Outlook Web Access team. It soon became a part of Internet Explorer 5. Renamed XMLHttpRequest and standardized by the World Wide Web Consortium, it has since become one of the cornerstones of the Ajax technology used to build advanced web apps. Outlook Web Access was later renamed Outlook Web App in 2010. An update on August 4, 2015, renamed OWA to "Outlook on the web", often referred to in brief as simply "Outlook". == Components == === Mail === Mail is the webmail component of Outlook on the web. The default view is a three column view with folders and groups on the left, an email message list in the middle, and the selected message on the right. With the 2015 update, Microsoft introduced the ability to pin, sweep and archive messages, and undo the last action, as well as richer image editing features. It can connect to other services such as GitHub and Twitter through Office 365 Connectors. Actionable Messages in emails allows a user to complete a task from within the email, such as retweeting a Tweet on Twitter or setting a meeting date on a calendar. Outlook on the web supports S/MIME and includes features for managing calendars, contacts, tasks, documents (used with SharePoint or Office Web Apps), and other mailbox content. In the Exchange 2007 release, Outlook on the web (still called Outlook Web App at the time) also offers read-only access to documents stored in SharePoint sites and network UNC shares. === Calendar === Calendar is the calendaring component of Outlook on the web. With the update, Microsoft added a weather forecast directly in the Calendar, as well as icons (or "charms") as visual cues for an event. In addition, email reminders came to all events, and a special Birthday and Holiday event calendars are created automatically. Calendars can be shared and there are multiple views such as day, week, month, and today. Another view is work week which includes Mondays through Fridays in the calendar view. Calendar's "Board View" feature allows for a customizable calendar with widgets such as Goal, Calendar, Tasks and Tips. Calendar details can be added with HTML and rich-text editing, and files can be attached to calendar events and appointments. === People === People is the contact manager component of Outlook on the web. A user can search and edit existing contacts, as well as create new ones. Contacts can be placed into folders and duplicate contacts can be linked from multiple sources such as LinkedIn or Twitter. In Outlook Mail, a contact can be created by clicking on an email address sender, which pulls down a contact card with an add button to add to Outlook People. Contacts can be imported as well as placed into a list that can be utilized when composing an email in Outlook Mail. People can also sync with friends and connections lists on LinkedIn, Facebook, and Twitter. === To Do === To Do was originally launched as Tasks for Outlook Web App. Microsoft was slowly rolling out a preview of Tasks to its consumer-based Outlook.com service that in May 2015, was announced to be moving to the Office 365 infrastructure. It was initially a part of Calendar as a view. Microsoft has separated the services into its own web app in Outlook on the web. In a post on the Office Blogs in 2015, Microsoft announced that Outlook Web App would be renamed Outlook on the web and that Tasks would move under that brand. A user can create tasks, put them into categories, and move them to another folder. A feature added was the ability to set due days and sort and filter the tasks according to those criteria. The app provides the user with fields such as subject, start and end dates, percent complete, priority, and how much work was put into each task. Rich editing features like bold, italic, underline, numbering, and bullet points were also introduced. Tasks can be edited and categorized according to how the user wishes them to be sorted. == Removed features == Outlook on the web has had two interfaces available: one with a complete feature set (known as Premium) and one with reduced functionality (known as Light or sometimes Lite). Prior to Exchange 2010, the Premium client required Internet Explorer. Exchange 2000 and 2003 require Internet Explorer 5 and later, and Exchange 2007 requires Internet Explorer 6 and later. Exchange 2010 supports a wider range of web browsers: Internet Explorer 7 or later, Firefox 3.01 or later, Chrome, or Safari 3.1 or later. However, Exchange 2010 restricts its Firefox and Safari support to macOS and Linux. In Exchange 2013, these browser restrictions were lifted. In Exchange 2010 and earlier, the Light user interface is rendered for browsers other than Internet Explorer. The basic interface did not support search on Exchange Server 2003. In Exchange Server 2007, the Light interface supported searching mail items; managing contacts and the calendar was also improved. The 2010 version can connect to an external email account. The ability to add new accounts to Outlook on the web using the Connected accounts feature was removed in September 2018 and all connected accounts stopped synchronizing email the following month.
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Monitoring as a service

Monitoring as a service (MaaS) is a cloud-based framework for the deployment of monitoring functionalities for various other services and applications within the cloud. The most common application for MaaS is online state monitoring, which continuously tracks certain states of applications, networks, systems, instances or any element that may be deployable within the cloud.
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Protocol Builder

Protocol Builder is a tool in programming languages to generate code to build protocols in a fast and reliable way. Network programming for all kinds of protocols (such as TCP, UDP, and SNMP) includes converting data to be transferred to raw bytes in the sending side and parsing these bytes in the receiving side. Protocol builders facilitate this stage, usually by automatically generating the code. Protocol Programming has many components to be developed, these are: server listener, server connection, client connection, packets, and loggers. Most protocol builders implement these components automatically so developers save time and money. Currently, there are two Protocol Builders in the market, one for C++ from UpRedSun which is for TCP and UDP protocols. The second one is for .Net languages which generates the code in C# for TCP Protocols, this tool is called .Net Protocol Builder.
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List of .NET libraries and frameworks

This article contains a list of libraries that can be used in .NET languages. These languages require .NET Framework, Mono, or .NET, which provide a basis for software development, platform independence, language interoperability and extensive framework libraries. Standard Libraries (including the Base Class Library) are not included in this article. == Introduction == Apps created with .NET Framework or .NET run in a software environment known as the Common Language Runtime (CLR), an application virtual machine that provides services such as security, memory management, and exception handling. The framework includes a large class library called Framework Class Library (FCL). Thanks to the hosting virtual machine, different languages that are compliant with the .NET Common Language Infrastructure (CLI) can operate on the same kind of data structures. These languages can therefore use the FCL and other .NET libraries that are also written in one of the CLI compliant languages. When the source code of such languages are compiled, the compiler generates platform-independent code in the Common Intermediate Language (CIL, also referred to as bytecode), which is stored in CLI assemblies. When a .NET app runs, the just-in-time compiler (JIT) turns the CIL code into platform-specific machine code. To improve performance, .NET Framework also comes with the Native Image Generator (NGEN), which performs ahead-of-time compilation to machine code. This architecture provides language interoperability. Each language can use code written in other languages. Calls from one language to another are exactly the same as would be within a single programming language. If a library is written in one CLI language, it can be used in other CLI languages. Moreover, apps that consist only of pure .NET assemblies, can be transferred to any platform that contains an implementation of CLI and run on that platform. For example, apps written using .NET can run on Windows, macOS, and various versions of Linux. .NET apps or their libraries, however, may depend on native platform features, e.g. COM. As such, platform independence of .NET apps depends on the ability to transfer necessary native libraries to target platforms. In 2019, the Windows Forms and Windows Presentation Foundation portions of .NET Framework were made open source. === .NET implementations === There are four primary .NET implementations that are actively developed and maintained: .NET Framework: The original .NET implementation that has existed since 2002. While not yet discontinued, Microsoft does not plan on releasing its next major version, 5.0. Mono: A cross-platform implementation of .NET Framework by Ximian, introduced in 2004. It is free and open-source. It is now developed by Xamarin, a subsidiary of Microsoft. Universal Windows Platform (UWP): An implementation of .NET used for building UWP apps. It's designed to unify development for different targeted types of devices, including PCs, tablets, phablets, phones, and the Xbox. .NET: A cross-platform re-implementation of .NET Framework, introduced in 2016 and initially called .NET Core. It is free and open-source. .NET superseded .NET Framework with the release of .NET 5. Each implementation of .NET includes the following components: One or more runtime environments, e.g. Common Language Runtime (CLR) for .NET Framework and CoreCLR for .NET A class library The .NET Standard is a set of common APIs that are implemented in the Base Class Library of any .NET implementation. The class library of each implementation must implement the .NET Standard, but may also implement additional APIs. Traditionally, .NET apps targeted a certain version of a .NET implementation, e.g. .NET Framework 4.6. Starting with the .NET Standard, an app can target a version of the .NET Standard and then it could be used (without recompiling) by any implementation that supports that level of the standard. This enables portability across different .NET implementations. The following table lists the .NET implementations that adhere to the .NET Standard and the version number at which each implementation became compliant with a given version of .NET Standard. For example, according to this table, .NET Core 3.0 was the first version of .NET Core that adhered to .NET Standard 2.1. This means that any version of .NET Core bigger than 3.0 (e.g. .NET Core 3.1) also adheres to .NET Standard 2.1. == Web frameworks == === ASP.NET === First released in 2002, ASP.NET is an open-source server-side web application framework designed for web development to produce dynamic web pages. It is the successor to Microsoft's Active Server Pages (ASP) technology, built on the Common Language Runtime (CLR). === ASP.NET Core === ASP.NET was completely rewritten in 2016 as a modular web framework, together with other frameworks like Entity Framework. The re-written framework uses the new open-source .NET Compiler Platform (also known by its codename "Roslyn") and is cross platform. The programming models ASP.NET MVC, ASP.NET Web API, and ASP.NET Web Pages (a model using only Razor pages) were merged into a unified MVC 6. === Blazor === Blazor is a free and open-source web framework that enables developers to create Single-page Web apps using C# and HTML in ASP.NET Razor pages ("components"). Blazor is part of the ASP.NET Core framework. Blazor Server apps are hosted on a web server, while Blazor WebAssembly apps are downloaded to the client's web browser before running. In addition, a Blazor Hybrid framework is available with server-based and client-based application components. == Numerical libraries == === Open-source numerical libraries === ==== AForge.NET ==== This is a computer vision and artificial intelligence library. It implements a number of genetic, fuzzy logic and machine learning algorithms with several architectures of artificial neural networks with corresponding training algorithms. ==== ALGLIB ==== This is a cross-platform open source numerical analysis and data processing library. It consists of algorithm collections written in different programming languages (C++, C#, FreePascal, Delphi, VBA) and has dual licensing – commercial and GPL. ==== Math.NET Numerics ==== This library aims to provide methods and algorithms for numerical computations in science, engineering and everyday use. Covered topics include special functions, linear algebra, probability models, random numbers, interpolation, integral transforms and more. MIT/X11 license. ==== Meta.Numerics ==== This is a library for advanced scientific computation in the .NET Framework. ==== ML.NET ==== This is a free software machine learning library. The preview release of ML.NET included transforms for feature engineering like n-gram creation, and learners to handle binary classification, multi-class classification, and regression tasks. Additional ML tasks like anomaly detection and recommendation systems have since been added, and other approaches like deep learning will be included in future versions. === Proprietary numerical libraries === ==== ILNumerics.Net ==== This is a high performance, typesafe numerical array set of classes and functions for general math, FFT and linear algebra. The library, developed for .NET/Mono, aims to provide 32- and 64-bit script-like syntax in C#, 2D & 3D plot controls, and efficient memory management. It is released under GPLv3 or commercial license. ==== Measurement Studio ==== This is an integrated suite of UI controls and class libraries for use in developing test and measurement applications. The analysis class libraries provide various digital signal processing, signal filtering, signal generation, peak detection, and other general mathematical functionality. ==== NMath ==== This is a numerical component library for the .NET platform developed by CenterSpace Software. It includes signal processing (FFT) classes, a linear algebra (LAPACK & BLAS) framework, and a statistics package. == 3D graphics == === Open-source 3D graphics === ==== Open Toolkit (OpenTK) ==== This is a low-level C# binding for OpenGL, OpenGL ES and OpenAL. It runs on Windows, Linux, Mac OS X, BSD, Android and iOS. It can be used standalone or integrated into a GUI. ==== Windows Presentation Foundation (WPF) ==== This is a graphical subsystem for rendering user interfaces, developed by Microsoft. It also contains a 3D rendering engine. In addition, interactive 2D content can be overlaid on 3D surfaces natively. It only runs on Windows operating systems. === Proprietary 3D graphics === ==== Unity ==== This is a cross-platform game engine developed by Unity Technologies and used to develop video games for PC, consoles, mobile devices and websites. == Image processing == === AForge.NET === This is a computer vision and artificial intelligence library. It implements a number of image processing algorithms and filters. It is released under the LGPLv3 and partly GPLv3 license. Majority of the library is written in C# and th
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Biomedical data science

Biomedical data science is a multidisciplinary field which leverages large volumes of data to promote biomedical innovation and discovery. Biomedical data science draws from various fields including Biostatistics, Biomedical informatics, and machine learning, with the goal of understanding biological and medical data. It can be viewed as the study and application of data science to solve biomedical problems. Modern biomedical datasets often have specific features which make their analyses difficult, including: Large numbers of feature (sometimes billions), typically far larger than the number of samples (typically tens or hundreds) Noisy and missing data Privacy concerns (e.g., electronic health record confidentiality) Requirement of interpretability from decision makers and regulatory bodies Many biomedical data science projects apply machine learning to such datasets. These characteristics, while also present in many data science applications more generally, make biomedical data science a specific field. Examples of biomedical data science research include: Computational genomics Computational imaging Electronic health records data mining Biomedical network science Clinical Natural Language Processing (NLP) == Computational Imaging and Deep Learning == Computational imaging is a cornerstone of biomedical data science, focusing on the development of algorithms to enhance, analyze, and interpret medical imagery. In recent years, the field has been transformed by the integration of deep learning, particularly through the use of Convolutional Neural Networks. Deep learning started from researchers manually defining characteristics like edge detection or texture representation learning. In a more modern approach of computational imaging, models automatically learn a hierarchy of features directly from raw pixel data. This overlap between data science and deep learning is applied across several key tasks: Classification: Identifying the presence of specific diseases, such as distinguishing between benign and malignant tumors in histopathology slides or detecting pneumonia in chest X-rays. Segmentation: The precise delineation of anatomical structures or lesions. A notable example is the U-Net architecture, which is widely used for biomedical image segmentation to help clinicians quantify organ volume or track tumor growth. Detection: Automating the localization of small objects, such as identifying microcalcifications in mammograms or polyps during colonoscopies. Registration: The process of aligning multiple images to provide a comprehensive view of the patient's anatomy. Even with all of these enhancements, the application of deep learning in medical imaging requires accomplishing vigorous challenges. An example of these changes is building large, annotated datasets and creating the imperative for model interpretability in clinical decision-making. == Electronic Health Records == Electronic Health Records (EHRs) are a digital alternative to patient paper charts, usually including individual records or population health information. EHRs can be used in a wide variety of applications, including research and analysation as they often include demographics, diagnoses, medications, test results, and personal statistics. === History === ==== 1960s ==== The earliest precursor is considered Dr. Lawrence Weed's problem-oriented medical record (POMR) published in the 1968 which sorts and groups medical records by medical diagnoses and symptoms. The POMR was the first system to organize based off of patient information rather than the source (doctors, nurses, attendings, etc.). In 1969, the Regenstrief Institute developed and published the Regenstrief Medical Record System which established electronic writing, storage, and retrieval of records which served as the basis for modern EHR systems. ==== 2000s ==== In 2009, the Health Information Technology for Economic and Clinical Health Act (HITECH Act) was passed in the United States. This act standardized privacy and distribution of EHRs and increased the acceptance and utilization of EHRs within medical and academic settings. == Artificial Intelligence and Machine Learning Applications == Machine Learning and Artificial Intelligence have become central tools in biomedical data science. Recent advances in large language models (LLMs) have expanded their role beyond text, with models trained directly on genomic sequences enabling tasks such as gene function prediction, variant effect analysis, and drug discovery. In clinical settings, Natural Language Processing (NLP) models are applied to electronic health records to extract structured insights from unstructured clinical notes and data, supporting diagnosis and treatment planning. Beyond genomics, AI models have been applied to protein structure prediction. AlphaFold, developed by Google DeepMind, uses deep learning to predict three-dimensional protein structures from amino acid sequences with high accuracy. These predictions have been used to support drug target identification and the study of disease mechanisms. == Knowledge Graphs == Knowledge graphs (KGs) are widely used in biomedical data science to represent and analyze complex relationships among biological and medical entities. By structuring data as nodes (e.g., genes, diseases, drugs) and edges (relationships), KGs enable computational methods to extract insights and support decision-making. These biomedical relationships can be efficiently modeled and queried using technologies such as Neo4j. === Biomedical Research Applications === KGs provide biomedical researchers with a way to model complex biological systems. They have been used to identify the relationships between diseases and biomolecules, support drug repurposing, and to uncover new biological insights. Additional applications include: Identification of novel antibiotic resistance genes through graph-based link prediction. Finding associations between miRNA and diseases. Prediction of protein-protein interactions. === Clinical Applications === In clinical settings, KGs can be used to make visual representations of a patient's electronic health records. The data obtained from these graphs can assist healthcare providers in improving patient diagnoses and prescribing more effective drugs. Additionally, embeddings derived from resources like the Unified Medical Language System (UMLS) enable natural language processing of clinical text and similarity analysis between medical concepts. === Limitations === Despite their advantages, knowledge graphs face several challenges. Some of these include: High algorithmic complexity and large biological datasets make the process computationally expensive. KG construction can be a time-consuming process that requires careful attention to assign appropriate node types and vocabularies. Using data from a wide range of datasets in one KG requires them to be effectively integrated. == Privacy == A primary challenge in biomedical data science is maintaining medical privacy. Conducting research requires that data be collected on a number of people for training and testing purposes and is stored within biomedical datasets. This poses a risk for violating patient confidentiality and may dissuade people from participating in studies. The main sources of health statistics are surveys administrative and medical records health care claims data, vital records surveillance disease registries grey literature and peer-reviewed literature. Large data collection is a useful tool for researching various medical conditions. Researchers use these large datasets of information to identify factors that may make people more susceptible to certain diseases. Large amounts of collected data can help researchers identify patterns for disease probabilities. The findings can show a person is more likely for a condition, or identify environmental, social, and personal habits that may lead to adverse health issues. Institutions researching using personal medical information come with a moral and legal responsibility to protect the use of that information. Protection of the collected information has become a big concern. Sophisticated and coordinated attacks on certain medical systems happen more frequently. Medical companies, medical insurance and private businesses have invested a great deal into the protection of personal data. Despite this, data breaches continue to be documented. The chart below shows the top healthcare breaches in 2025. For these reasons, many people have reservations about giving up their personal data. Aside from the legitimate use of personal data there have been instances where companies have found methods to profit from brokering medical information. Concerns exist regarding unauthorized use of sensitive information within these data companies. If a person is identified within a dataset, then sensitive data can be used to discriminate against them. For example, insurance companies may charge a hi
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Cloud Security Alliance

Cloud Security Alliance (CSA) is a not-for-profit organization with the mission to "promote the use of best practices for providing security assurance within cloud computing, artificial intelligence and to provide education on the uses of cloud computing to help secure all other forms of computing." The CSA has over 80,000 individual members worldwide. The CSA gained significant reputability in 2011 when the American Presidential Administration selected the CSA Summit as the venue for announcing the federal government’s cloud computing strategy. == History == The CSA was formed in December 2008 as a coalition by individuals who saw the need to provide objective enterprise user guidance on the adoption and use of cloud computing. Its initial work product, Security Guidance for Critical Areas of Focus in Cloud Computing, was put together in a Wiki-style by dozens of volunteers. In 2014, the Chairman of the Board of the CSA was Dave Cullinane, VP of Global Security and Privacy for Catalina Marketing, St. Petersburg, Florida, and former CISO for eBay. Cullinane has said, "If you have an application exposed to the Internet that will allow people to make money, it will be probed." == Profile == In 2009, the Cloud Security Alliance incorporated in Nevada as a Corporation and achieved US Federal 501(c)6 non-profit status. It is registered as a Foreign Non-Profit Corporation in Washington. == Policy maker support == The CSA works to support a number of global policy makers in their focus on cloud security initiatives including the National Institute of Standards and Technology (NIST), European Commission, Singapore Government, and other data protection authorities. In March 2012, the CSA was selected to partner with three of Europe’s largest research centers (CERN, EMBL and ESA) to launch Helix Nebula – The Science Cloud. == Size == The Cloud Security Alliance employs roughly sixty full-time and contract staff worldwide. It has several thousand active volunteers participating in research, working groups and chapters at any time. == Membership == According to CSA, they are a member-driven organization, chartered with promoting the use of best practices for providing security assurance within Cloud Computing, and providing education on the uses of Cloud Computing to help secure all other forms of computing. === Individuals === Individuals who are interested in cloud computing and have experience to assist in making it more secure receive a complimentary individual membership based on a minimum level of participation. === Chapters === The Cloud Security Alliance has a network of chapters worldwide. Chapters are separate legal entities from the Cloud Security Alliance, but operate within guidelines set down by the Cloud Security Alliance In the United States, Chapters may elect to benefit from the non-profit tax shield that the Cloud Security Alliance has. Chapters are encouraged to hold local meetings and participate in areas of research. Chapter activities are coordinated by the Cloud Security Alliance worldwide. === International scope === There are separate legal entities in Europe and Asia Pacific, called Cloud Security Alliance (Europe), a Scottish company in the United Kingdom, and Cloud Security Alliance Asia Pacific Ltd, in Singapore. Each legal entity is responsible for overseeing all Cloud Security Alliance-related activities in their respective regions. These legal entities operate under an agreement with Cloud Security Alliance that give it oversight power and have separate Boards of Directors. Both are companies Limited By Guarantee. The Managing Directors of each are members of the Executive Team of Cloud Security Alliance. == Areas of research == The Cloud Security Alliance has 25+ active working groups. Key areas of research include cloud standards, certification, education and training, guidance and tools, global reach, and driving innovation. Security Guidance for Critical Areas of Focus in Cloud Computing. Foundational best practices for securing cloud computing. Top Threats to Cloud Computing. Helps organizations make educated risk management decisions regarding their cloud adoption strategies. GRC (Governance, Risk and Compliance) Stack. A toolkit for key stakeholders to instrument and assess clouds against industry established best practices, standards and critical compliance requirements. Cloud Controls Matrix (CCM). Security controls framework for cloud provider and cloud consumers. CloudTrust Protocol. The mechanism by which cloud service consumers ask for and receive information about the elements of transparency as applied to cloud service providers. Consensus Assessments Initiative Research. Tools and processes to perform consistent measurements of cloud providers. Software Defined Perimeter. A proposed security framework that can be deployed to protect application infrastructure from network-based attacks. It will incorporate standards from organizations such as OASIS and NIST and security concepts from organizations like the U.S. DoD into an integrated framework. == Working groups and initiatives == Mobile Working Group Big Data Working Group Security as a Service Working Group Trusted Cloud Initiative CloudAudit CloudCERT CloudSIRT Cloud Metrics Security, Trust and Assurance Registry (STAR) Cloud Data Governance Turbot (business) Blockchain/Distributed Ledger
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