Squirrel Ai Learning is an international educational technology company that specializes in intelligent adaptive learning and was one of the first companies in the world to offer large scale AI-powered adaptive education solutions. == Methodology == Squirrel Ai Learning uses artificial intelligence to tailor lesson plans to each individual student. The company's AI researchers have access to the world's largest student databases, which are used to train the AI algorithms. Squirrel Ai Learning works with teachers to identify the most fine-grained possible concepts ("knowledge points") for a course in order to precisely target learning gaps. For example, middle school mathematics is broken into over 10,000 points such as rational numbers, the properties of a triangle, and the Pythagorean theorem. Each point is linked to related items, forming a "knowledge graph". Each knowledge point is addressed by videos, examples and practice problems. A textbook might address 3,000 points; ALEKS, another adaptive learning platform, uses 1,000. Each student begins with a diagnostic test to identify where to begin their learning. The system continues to refine its graph as more students proceed. Learning is not student-directed. The system decides the order of topics. == History and milestones == Squirrel Ai Learning was founded by Derek Haoyang Li in 2014. In March, 2017, The Squirrel Ai Intelligent Adaptive Learning System (IALS) was launched. IALS utilizes artificial intelligence to customize lessons, practice and evaluations for each individual student. In 2018, Squirrel Ai Learning established a joint research lab of AI adaptive learning with the institute of Automation of the Chinese Academy of Sciences. By 2019, Squirrel Ai Learning had opened 2,000 learning centers in 200 cities and registered over a million students in Asia. In 2019, Squirrel Ai Learning opened a research lab in partnership with Carnegie Mellon University. As of 2019, Squirrel Ai Learning had raised over $180 million in funding and in 2018 it surpassed $1 billion in valuation. In 2020, Squirrel Ai Learning launched the $1 million AAAI Squirrel AI Award for Artificial Intelligence for the Benefit of Humanity in partnership with AAAI. The inaugural award was given to Regina Barzilay for her work developing machine learning models to address drug synthesis and early-stage breast cancer diagnosis. In 2020, Squirrel Ai Learning established strategic partnership with DingTalk, Alibaba Group. As of 2021, Squirrel Ai Learning had served over 60,000 public schools, in over 1200 cities in Asia. Squirrel Ai plans to start offering its services in the United States in 2026. The American arm is separate from the Chinese company to avoid regulatory hurdles. As of January 2026, it had set up an "independent technology platform" in the US. == Recognition == Squirrel Ai Learning has gained recognition both in Asia and internationally including: Squirrel Ai Learning was named one of the World's Top 30 AI application case in the 2018 Synced Machine Intelligence Awards. In June 2019, Squirrel Ai Learning was named as one of the 50 smartest companies in China by MIT technology review. Squirrel Ai Learning won the GITEX 2019 Best Education Technology Award. In 2020, Squirrel Ai Learning won the UNESCO AI Innovation Award. Squirrel Ai Learning was listed in the 2020 CB Insight's AI 100, CB Insights' annual ranking of the 100 most promising AI startups in the world. Squirrel Ai Learning won Edtech Review's Best AI in Education Company of the Year award 2020.
Scientific Working Group – Imaging Technology
The Scientific Working Group on Imaging Technology was convened by the Federal Bureau of Investigation in 1997 to provide guidance to law enforcement agencies and others in the criminal justice system regarding the best practices for photography, videography, and video and image analysis. This group was terminated in 2015. == History == As technology has advanced through the years, law enforcement has needed to stay abreast of emerging technological advances and use these in the investigation of crime. A factor that is considered when new technology is used in these investigations is the determination of whether the use of that new technology will be admissible in court. The judicial system in the United States currently has two standards used in the determination of admissibility of testimony regarding scientific evidence; the Daubert Standard and the Frye Standard. These standards guide the courts in the admissibility of testimony derived from the use of new technologies and scientific techniques. The Federal Bureau of Investigation (FBI), seeking to address possible admissibility issues with such testimony, established Scientific Working Groups starting with the Scientific Working Group on DNA Analysis and Methods (SWGDAM) in 1988. The goal of these groups is to open lines of communication between law enforcement agencies and forensic laboratories around the world while providing guidance on the use of new and innovative technologies and techniques. This guidance can lead to admissibility of evidence and/or testimony, provided proper methods in the collection of evidence and its analysis are employed. In 2009, the National Academy of Sciences released a report entitled, "Strengthening Forensic Science in the United States: A Path Forward." This report addresses many topics including challenges and disparities facing the forensic science community, standardization, certification of practitioners and accreditation of their respective entities, problems related to the interpretation of forensic evidence, the need for research, and the admission of forensic science evidence in litigation. This report mentions the Scientific Working Groups and their role in forensic science. The history of imaging technology (photography) can be said to extend back to the times of Chinese philosopher Mo-Ti (470-390 B.C.) who described the principles behind the precursor to the camera obscura. Since that time, advances in imaging technology include the discovery of chemical photographic processes in the 19th century and the use of electronic imaging technology that includes analog video cameras and digital video and still cameras. By the mid 1990s, it was apparent that technologically advanced camera systems such as these were being adopted for use in the criminal justice system. This led the FBI to convene a meeting of individuals working in the field of forensic imaging from federal, state, local, and foreign law enforcement, and the U.S. military, during the summer of 1997. As a result of this meeting, the Technical Working Group on Imaging Technology was formed from a core group of the meeting’s participants. This group later became the Scientific Working Group on Imaging Technology (SWGIT). Prior to the inception of SWGIT, some law enforcement agencies began adopting digital imaging technology. Due to the lack of guidelines or standards, some of these agencies attempted to replace all their film cameras with substandard digital cameras, only to find that the equipment they had purchased was not capable of accomplishing the mission for which they were intended. At that time only low resolution digital cameras were deemed affordable by some law enforcement agencies. Some of these agencies were forced to rethink their photography procedures and reverted to the use of film cameras or replaced their low-resolution digital cameras with higher quality, more expensive equipment. Also lacking at this early stage was guidance on how to store and archive digital image files. When SWGIT was formed, it was tasked with providing guidance to law enforcement and others in the criminal justice system by releasing documents that describe the best practices and guidelines for the use of imaging technology, to include these concerns and many others. This group was terminated in 2015. == SWGIT Function == During its existence, SWGIT provided information on the appropriate use of various imaging technologies including both established and new. This was accomplished through the release of documents such as the SWGIT Best Practices documents. As changes in technology occurred, these documents were updated. Over the course of its existence, SWGIT collaborated with other Scientific Working Groups to address imaging concerns within their respective disciplines. SWGIT published over 20 documents that dealt specifically with imaging technology. SWGIT also co-published documents with the Scientific Working Group on Digital Evidence (SWGDE) that had a component or components dealing with imaging technology. SWGIT also provided imaging technology guidance and input for documents from the Scientific Working Group on Friction Ridge Analysis, Study and Technology (SWGFAST), the Scientific Working Group for Forensic Document Examination (SWGDOC), and the Scientific Working Group on Shoeprint and Tire Tread Evidence (SWGTREAD). SWGIT assisted the American Society of Crime Lab Directors/Laboratory Accreditation Board (ASCLD/LAB) in the writing of definitions and standards for the accreditation of Digital and Multimedia Evidence sections of crime laboratories. In addition to releasing documents, SWGIT members disseminated best practices for law enforcement professionals where imaging technology was concerned. This was carried out by attending and lecturing at meetings and conferences of various forensic organizations that included: The American Academy of Forensic Sciences (AAFS) The International Association for Identification (IAI) The Law Enforcement and Emergency Services Video Association (LEVA) The American Society of Crime Lab Directors (ASCLD) The SWGIT membership consisted of approximately fifty scientists, photographers, instructors, and managers from more than two dozen federal, state, and local law enforcement agencies, as well as from the academic and research communities. The membership elected its officers from within. SWGIT was composed of the Executive Committee, four standing subcommittees, and ad hoc subcommittees appointed on an as-needed basis. The standing subcommittees were: Image Analysis, Forensic Photography, Video, and Outreach. This group was terminated in 2015. == Legal Proceedings == The following court cases have conducted Daubert v. Merrell Dow Pharm., Inc., 509 U.S. 579 (1993) hearings in which SWGIT best practice documents have been cited as accepted protocol, methodology, and as generally accepted techniques in the forensic community: U. S. v. Rudy Frabizio, U.S. District Court, Boston, MA, 2008 (Image Authentication) U.S. v. Nobumochi Furukawa, U.S. District Court, Minnesota, 2007 (Video Authentication) U.S. v. John Stroman, U.S. District Court, South Carolina, 2007 (Facial Comparison Analysis) State of Texas v. Daniel Day, Tarrant County Texas, 2005 (Camera Identification to Images) U.S. v. Marc Watzman, U.S. District Court, Northern Illinois, 2004 (Video Authentication) U.S. v. McKreith, U.S. District Court, Fort Lauderdale, FL, 2002 (Photo comparison of shirt) == Termination == This group was unfunded by the FBI in 2015.
BabelNet
BabelNet is a multilingual lexical-semantic knowledge graph, ontology and encyclopedic dictionary developed at the NLP group of the Sapienza University of Rome under the supervision of Roberto Navigli. BabelNet was automatically created by linking Wikipedia to the most popular computational lexicon of the English language, WordNet. The integration is done using an automatic mapping and by filling in lexical gaps in resource-poor languages by using statistical machine translation. The result is an encyclopedic dictionary that provides concepts and named entities lexicalized in many languages and connected with large amounts of semantic relations. Additional lexicalizations and definitions are added by linking to free-license wordnets, OmegaWiki, the English Wiktionary, Wikidata, FrameNet, VerbNet and others. Similarly to WordNet, BabelNet groups words in different languages into sets of synonyms, called Babel synsets. For each Babel synset, BabelNet provides short definitions (called glosses) in many languages harvested from both WordNet and Wikipedia. == Statistics of BabelNet == As of December 2023, BabelNet (version 5.3) covers 600 languages. It contains almost 23 million synsets and around 1.7 billion word senses (regardless of their language). Each Babel synset contains 2 synonyms per language, i.e., word senses, on average. The semantic network includes all the lexico-semantic relations from WordNet (hypernymy and hyponymy, meronymy and holonymy, antonymy and synonymy, etc., totaling around 364,000 relation edges) as well as an underspecified relatedness relation from Wikipedia (totaling around 1.9 billion edges). Version 5.3 also associates around 61 million images with Babel synsets and provides a Lemon RDF encoding of the resource, available via a SPARQL endpoint. 2.67 million synsets are assigned domain labels. == Applications == BabelNet has been shown to enable multilingual natural language processing applications. The lexicalized knowledge available in BabelNet has been shown to obtain state-of-the-art results in: Semantic relatedness, Multilingual word-sense disambiguation and entity linking, with the Babelfy system, Video games with a purpose. == Prizes and acknowledgments == BabelNet received the META prize 2015 for "groundbreaking work in overcoming language barriers through a multilingual lexicalised semantic network and ontology making use of heterogeneous data sources". The Artificial Intelligence Journal paper that describes BabelNet won the Prominent Paper Award in 2017. BabelNet featured prominently in a Time magazine article about the new age of innovative and up-to-date lexical knowledge resources available on the Web.
ChipTest
ChipTest was a 1985 chess playing computer built by Feng-hsiung Hsu, Thomas Anantharaman and Murray Campbell at Carnegie Mellon University. It is the predecessor of Deep Thought which in turn evolved into Deep Blue. == History == ChipTest was based on a special VLSI-technology move generator chip developed by Hsu. ChipTest was controlled by a Sun-3/160 workstation and capable of searching approximately 50,000 moves per second. Hsu and Anantharaman entered ChipTest in the 1986 North American Computer Chess Championship, and it was only partially tested when the tournament began. It lost its first two rounds, but finished with an even score. In August 1987, ChipTest was overhauled and renamed ChipTest-M, M standing for microcode. The new version had eliminated ChipTest's bugs and was ten times faster, searching 500,000 moves per second and running on a Sun-4 workstation. ChipTest-M won the North American Computer Chess Championship in 1987 with a 4–0 sweep. ChipTest was invited to play in the 1987 American Open, but the team did not enter due to an objection by the HiTech team, also from Carnegie Mellon University. HiTech and ChipTest shared some code, and Hitech was already playing in the tournament. The two teams became rivals. Designing and implementing ChipTest revealed many possibilities for improvement, so the designers started on a new machine. Deep Thought 0.01 was created in May 1988 and the version 0.02 in November the same year. This new version had two customized VLSI chess processors and it was able to search 720,000 moves per second. With the "0.02" dropped from its name, Deep Thought won the World Computer Chess Championship with a perfect 5–0 score in 1989.
Semantic analysis (knowledge representation)
Semantic analysis is a method for eliciting and representing knowledge about organisations. Initially the problem must be defined by domain experts and passed to the project analyst(s). The next step is the generation of candidate affordances. This step will generate a list of semantic units that may be included in the schema. The candidate grouping follows where some of the semantic units that will appear in the schema are placed in simple groups. Finally the groups will be integrated together into an ontology chart. Semantic analysis always starts from the problem definition which if not clear, require the analyst to employ relevant literature, interviews with the stakeholders and other techniques towards collecting supplementary information. All assumptions made must be genuine and not limiting the system.
Common data model
A common data model (CDM) can refer to any standardised data model which allows for data and information exchange between different applications and data sources. Common data models aim to standardise logical infrastructure so that related applications can "operate on and share the same data", and can be seen as a way to "organize data from many sources that are in different formats into a standard structure". A common data model has been described as one of the components of a "strong information system". A standardised common data model has also been described as a typical component of a well designed agile application besides a common communication protocol. Providing a single common data model within an organisation is one of the typical tasks of a data warehouse. == Examples of common data models == === Border crossings === X-trans.eu was a cross-border pilot project between the Free State of Bavaria (Germany) and Upper Austria with the aim of developing a faster procedure for the application and approval of cross-border large-capacity transports. The portal was based on a common data model that contained all the information required for approval. === Climate data === The Climate Data Store Common Data Model is a common data model set up by the Copernicus Climate Change Service for harmonising essential climate variables from different sources and data providers. === General information technology === Within service-oriented architecture, S-RAMP is a specification released by HP, IBM, Software AG, TIBCO, and Red Hat which defines a common data model for SOA repositories as well as an interaction protocol to facilitate the use of common tooling and sharing of data. Content Management Interoperability Services (CMIS) is an open standard for inter-operation of different content management systems over the internet, and provides a common data model for typed files and folders used with version control. The NetCDF software libraries for array-oriented scientific data implements a common data model called the NetCDF Java common data model, which consists of three layers built on top of each other to add successively richer semantics. === Health === Within genomic and medical data, the Observational Medical Outcomes Partnership (OMOP) research program established under the U.S. National Institutes of Health has created a common data model for claims and electronic health records which can accommodate data from different sources around the world. PCORnet, which was developed by the Patient-Centered Outcomes Research Institute, is another common data model for health data including electronic health records and patient claims. The Sentinel Common Data Model was initially started as Mini-Sentinel in 2008. It is used by the Sentinel Initiative of the USA's Food and Drug Administration. The Generalized Data Model was first published in 2019. It was designed to be a stand-alone data model as well as to allow for further transformation into other data models (e.g., OMOP, PCORNet, Sentinel). It has a hierarchical structure to flexibly capture relationships among data elements. The JANUS clinical trial data repository also provides a common data model which is based on the SDTM standard to represent clinical data submitted to regulatory agencies, such as tabulation datasets, patient profiles, listings, etc. === Logistics === SX000i is a specification developed jointly by the Aerospace and Defence Industries Association of Europe (ASD) and the American Aerospace Industries Association (AIA) to provide information, guidance and instructions to ensure compatibility and the commonality. The associated SX002D specification contains a common data model. === Microsoft Common Data Model === The Microsoft Common Data Model is a collection of many standardised extensible data schemas with entities, attributes, semantic metadata, and relationships, which represent commonly used concepts and activities in various businesses areas. It is maintained by Microsoft and its partners, and is published on GitHub. Microsoft's Common Data Model is used amongst others in Microsoft Dataverse and with various Microsoft Power Platform and Microsoft Dynamics 365 services. === Rail transport === RailTopoModel is a common data model for the railway sector. === Other === There are many more examples of various common data models for different uses published by different sources.
AlphaFold
AlphaFold is an artificial intelligence (AI) program developed by DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018) placed first in the overall rankings of the 13th Critical Assessment of Structure Prediction (CASP) in December 2018. It was particularly successful at predicting the most accurate structures for targets rated as most difficult by the competition organizers, where no existing template structures were available from proteins with partially similar sequences. AlphaFold 2 (2020) repeated this placement in the CASP14 competition in November 2020. It achieved a level of accuracy much higher than any other entry. It scored above 90 on CASP's global distance test (GDT) for approximately two-thirds of the proteins, a test measuring the similarity between a computationally predicted structure and the experimentally determined structure, where 100 represents a complete match. The inclusion of metagenomic data has improved the quality of the prediction of multiple sequence alignments. One of the biggest sources of the training data was the custom-built Big Fantastic Database of 65,983,866 protein families, represented as multiple sequence alignments and Hidden Markov models, covering 2,204,359,010 protein sequences from reference databases, metagenomes, and metatranscriptomes. AlphaFold 2's results at CASP14 were described as "astounding" and "transformational". However, some researchers noted that the accuracy was insufficient for a third of its predictions, and that it did not reveal the underlying mechanism or rules of protein folding for the protein folding problem, which remains unsolved. Despite this, the technical achievement was widely recognized. On 15 July 2021, the AlphaFold 2 paper was published in Nature as an advance access publication alongside open source software and a searchable database of species proteomes. As of November 2025, the paper had been cited nearly 43,000 times. AlphaFold 3 was announced on 8 May 2024. It can predict the structure of complexes created by proteins with DNA, RNA, various ligands, and ions. The new prediction method shows a minimum 50% improvement in accuracy for protein interactions with other molecules compared to existing methods. Demis Hassabis and John Jumper shared one half of the 2024 Nobel Prize in Chemistry, awarded "for protein structure prediction," while the other half went to David Baker "for computational protein design." Hassabis and Jumper had previously won the Breakthrough Prize in Life Sciences and the Albert Lasker Award for Basic Medical Research in 2023 for their leadership of the AlphaFold project. == Background == Proteins consist of chains of amino acids which spontaneously fold to form the three dimensional (3-D) structures of the proteins. The 3-D structure is crucial to understanding the biological function of the protein. Protein structures can be determined experimentally through techniques such as X-ray crystallography, cryo-electron microscopy and nuclear magnetic resonance (NMR), which are all expensive and time-consuming. Such efforts, using the experimental methods, have identified the structures of about 170,000 proteins over the last 60 years, while there are over 200 million known proteins across all life forms. Over the years, researchers have applied numerous computational methods to predict the 3D structures of proteins from their amino acid sequences, accuracy of such methods in best possible scenario is close to experimental techniques (NMR) by the use of homology modeling based on molecular evolution. CASP, which was launched in 1994 to challenge the scientific community to produce their best protein structure predictions, found that GDT scores of only about 40 out of 100 can be achieved for the most difficult proteins by 2016. AlphaFold started competing in the 2018 CASP using an artificial intelligence (AI) deep learning technique. == Algorithm == DeepMind is known to have trained the program on over 170,000 protein structures from the Protein Data Bank, a public repository of protein sequences and structures. The program uses a form of attention network, a deep learning technique that focuses on having the AI identify parts of a larger problem, then piece it together to obtain the overall solution. The overall training was conducted on processing power between 100 and 200 GPUs. === AlphaFold 1 (2018) === AlphaFold 1 (2018) was built on work developed by various teams in the 2010s, work that looked at the large databases of related protein sequences now available from many different organisms (most without known 3D structures), to try to find changes at different residues (peptides) that appeared to be correlated, even though the residues were not consecutive in the main chain. Such correlations suggest that the residues may be close to each other physically, even though not close in the sequence, allowing a contact map to be estimated. Building on recent work prior to 2018, AlphaFold 1 extended this by estimating a probability distribution for the distances between residues, effectively transforming the contact map into a distance map. It also used more advanced learning methods than previously to develop the inference. The code was not made publicly available, except to run on sequences of proteins in the 2018 CASP competition. === AlphaFold 2 (2020) === The 2020 version of the program (AlphaFold 2, 2020) is significantly different from the original version that won CASP 13 in 2018, according to the team at DeepMind. AlphaFold 1 used a number of separately trained modules to produce a guide potential, which was then combined with a physics-based energy potential. AlphaFold 2 replaced this with a system of interconnected sub-networks, forming a single, differentiable, end-to-end model based on pattern recognition. This model was trained in an integrated manner. After the neural network's prediction converges, a final refinement step applies local physical constraints using energy minimization based on the AMBER force field. This step only slightly adjusts the predicted structure. A key part of the 2020 system are two modules, believed to be based on a transformer design, which are used to progressively refine a vector of information for each relationship (or "edge" in graph-theory terminology) between an amino acid residue of the protein and another amino acid residue (these relationships are represented by the array shown in green); and between each amino acid position and each different sequences in the input sequence alignment (these relationships are represented by the array shown in red). Internally these refinement transformations contain layers that have the effect of bringing relevant data together and filtering out irrelevant data (the "attention mechanism") for these relationships, in a context-dependent way, learned from training data. These transformations are iterated, the updated information output by one step becoming the input of the next, with the sharpened residue/residue information feeding into the update of the residue/sequence information, and then the improved residue/sequence information feeding into the update of the residue/residue information. As the iteration progresses, according to one report, the "attention algorithm ... mimics the way a person might assemble a jigsaw puzzle: first connecting pieces in small clumps—in this case clusters of amino acids—and then searching for ways to join the clumps in a larger whole." The output of these iterations then informs the final structure prediction module, which also uses transformers, and is itself then iterated. In an example presented by DeepMind, the structure prediction module achieved a correct topology for the target protein on its first iteration, scored as having a GDT_TS of 78, but with a large number (90%) of stereochemical violations – i.e. unphysical bond angles or lengths. With subsequent iterations the number of stereochemical violations fell. By the third iteration the GDT_TS of the prediction was approaching 90, and by the eighth iteration the number of stereochemical violations was approaching zero. The training data was originally restricted to single peptide chains. However, the October 2021 update, named AlphaFold-Multimer, included protein complexes in its training data. DeepMind stated this update succeeded about 70% of the time at accurately predicting protein-protein interactions. === AlphaFold 3 (2024) === Announced on 8 May 2024, AlphaFold 3 was co-developed by Google DeepMind and Isomorphic Labs, both subsidiaries of Alphabet. AlphaFold 3 is not limited to proteins, as it can also predict the structures of protein complexes with DNA, RNA, post-translational modifications and selected ligands and ions. AlphaFold 3 introduces the "Pairformer," a deep learning architecture inspired by the transformer, which is considered similar to, but si