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  • Structural synthesis of programs

    Structural synthesis of programs

    Structural synthesis of programs (SSP) is a special form of (automatic) program synthesis that is based on propositional calculus. More precisely, it uses intuitionistic logic for describing the structure of a program in such a detail that the program can be automatically composed from pieces like subroutines or even computer commands. It is assumed that these pieces have been implemented correctly, hence no correctness verification of these pieces is needed. SSP is well suited for automatic composition of services for service-oriented architectures and for synthesis of large simulation programs. == History == Automatic program synthesis began in the artificial intelligence field, with software intended for automatic problem solving. The first program synthesizer was developed by Cordell Green in 1969. At about the same time, mathematicians including R. Constable, Z. Manna, and R. Waldinger explained the possible use of formal logic for automatic program synthesis. Practically applicable program synthesizers appeared considerably later. The idea of structural synthesis of programs was introduced at a conference on algorithms in modern mathematics and computer science organized by Andrey Ershov and Donald Knuth in 1979. The idea originated from G. Pólya’s well-known book on problem solving. The method for devising a plan for solving a problem in SSP was presented as a formal system. The inference rules of the system were restructured and justified in logic by G. Mints and E. Tyugu in 1982. A programming tool PRIZ that uses SSP was developed in the 1980s. A recent Integrated development environment that supports SSP is CoCoViLa — a model-based software development platform for implementing domain specific languages and developing large Java programs. == The logic of SSP == Structural synthesis of programs is a method for composing programs from already implemented components (e.g. from computer commands or software object methods) that can be considered as functions. A specification for synthesis is given in intuitionistic propositional logic by writing axioms about the applicability of functions. An axiom about the applicability of a function f is a logical implication X1 ∧ X2 ∧ ... ∧ Xm → Y1 ∧ Y2 ... Yn, where X1, X2, ... Xm are preconditions and Y1, Y2, ... Yn are postconditions of the application of the function f. In intuitionistic logic, the function f is called a realization of this formula. A precondition can be a proposition stating that input data exists, e.g. Xi may have the meaning “variable xi has received a value”, but it may denote also some other condition, e.g. that resources needed for using the function f are available, etc. A precondition may also be an implication of the same form as the axiom given above; then it is called a subtask. A subtask denotes a function that must be available as an input when the function f is applied. This function itself must be synthesized in the process of SSP. In this case, realization of the axiom is a higher order function, i.e., a function that uses another function as an input. For instance, the formula (state → nextState) ∧ initialState → result can specify a higher order function with two inputs and an output result. The first input is a function that has to be synthesized for computing nextState from state, and the second input is initialState. Higher order functions give generality to the SSP – any control structure needed in a synthesized program can be preprogrammed and used then automatically with a respective specification. In particular, the last axiom presented here is a specification of a complex program – a simulation engine for simulating dynamic systems on models where nextState can be computed from state of the system.

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  • Wolfram Mathematica

    Wolfram Mathematica

    Wolfram Mathematica (also known as Mathematica) is a software system with built-in libraries for several areas of technical computing that allows machine learning, statistics, symbolic computation, data manipulation, network analysis, time series analysis, NLP, optimization, plotting functions and various types of data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other programming languages. It was conceived by Stephen Wolfram, and is developed by Wolfram Research of Champaign, Illinois. The Wolfram Language is the programming language used in Mathematica. Mathematica 1.0 was released on June 23, 1988 in Champaign, Illinois and Santa Clara, California. Mathematica's Wolfram Language is fundamentally based on Lisp; for example, the Mathematica command Most is identically equal to the Lisp command butlast. == Notebook interface == Mathematica is split into two parts: the kernel and the front end. The kernel interprets expressions (Wolfram Language code) and returns result expressions, which can then be displayed by the front end. The original front end, designed by Theodore Gray in 1988, consists of a notebook interface and allows the creation and editing of notebook documents that can contain code, plaintext, images, and graphics. Code development is also supported through support in a range of standard integrated development environment (IDE) including Eclipse, IntelliJ IDEA, Atom, Vim, Visual Studio Code and Git. The Mathematica Kernel also includes a command line front end. Other interfaces include JMath, based on GNU Readline and WolframScript which runs self-contained Mathematica programs (with arguments) from the UNIX command line. == High-performance computing == Capabilities for high-performance computing were extended with the introduction of packed arrays in version 4 (1999) and sparse matrices (version 5, 2003), and by adopting the GNU Multiple Precision Arithmetic Library to evaluate high-precision arithmetic. Version 5.2 (2005) added automatic multi-threading when computations are performed on multi-core computers. This release included CPU-specific optimized libraries. In addition Mathematica is supported by third party specialist acceleration hardware such as ClearSpeed. In 2002, gridMathematica was introduced to allow user level parallel programming on heterogeneous clusters and multiprocessor systems and in 2008 parallel computing technology was included in all Mathematica licenses including support for grid technology such as Windows HPC Server 2008, Microsoft Compute Cluster Server and Sun Grid. Support for CUDA and OpenCL GPU hardware was added in 2010. == Extensions == As of Version 14, there are 6,602 built-in functions and symbols in the Wolfram Language. Stephen Wolfram announced the launch of the Wolfram Function Repository in June 2019 as a way for the public Wolfram community to contribute functionality to the Wolfram Language. There are currently more than 3000 functions contributed as Resource Functions. In addition to the Wolfram Function Repository, there is a Wolfram Data Repository with computable data and the Wolfram Neural Net Repository for machine learning. Wolfram Mathematica is the basis of the Combinatorica package, which adds discrete mathematics functionality in combinatorics and graph theory to the program. == Connections to other applications, programming languages, and services == Communication with other applications can be done using a protocol called Wolfram Symbolic Transfer Protocol (WSTP). It allows communication between the Wolfram Mathematica kernel and the front end and provides a general interface between the kernel and other applications. Wolfram Research freely distributes a developer kit for linking applications written in the programming language C to the Mathematica kernel through WSTP using J/Link., a Java program that can ask Mathematica to perform computations. Similar functionality is achieved with .NET /Link, but with .NET programs instead of Java programs. Other languages that connect to Mathematica include Haskell, AppleScript, Racket, Visual Basic, Python, and Clojure. Mathematica supports the generation and execution of Modelica models for systems modeling and connects with Wolfram System Modeler. Links are also available to many third-party software packages and APIs. Mathematica can also capture real-time data from a variety of sources and can read and write to public blockchains (Bitcoin, Ethereum, and ARK). It supports import and export of over 220 data, image, video, sound, computer-aided design (CAD), geographic information systems (GIS), document, and biomedical formats. In 2019, support was added for compiling Wolfram Language code to LLVM. Version 12.3 of the Wolfram Language added support for Arduino. == Computable data == Mathematica is also integrated with Wolfram Alpha, an online answer engine that provides additional data, some of which is kept updated in real time, for users who use Mathematica with an internet connection. Some of the data sets include astronomical, chemical, geopolitical, language, biomedical, airplane, and weather data, in addition to mathematical data (such as knots and polyhedra). == Reception == BYTE in 1989 listed Mathematica as among the "Distinction" winners of the BYTE Awards, stating that it "is another breakthrough Macintosh application ... it could enable you to absorb the algebra and calculus that seemed impossible to comprehend from a textbook". Mathematica has been criticized for being closed source. Wolfram Research claims keeping Mathematica closed source is central to its business model and the continuity of the software.

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  • FERET database

    FERET database

    The Facial Recognition Technology (FERET) database is a dataset used for facial recognition system evaluation as part of the Face Recognition Technology (FERET) program. It was first established in 1993 under a collaborative effort between Harry Wechsler at George Mason University and Jonathon Phillips at the Army Research Laboratory in Adelphi, Maryland. The FERET database serves as a standard database of facial images for researchers to use to develop various algorithms and report results. The use of a common database also allowed one to compare the effectiveness of different approaches in methodology and gauge their strengths and weaknesses. The facial images for the database were collected between December 1993 and August 1996, accumulating a total of 14,126 images pertaining to 1,199 individuals along with 365 duplicate sets of images that were taken on a different day. In 2003, the Defense Advanced Research Projects Agency (DARPA) released a high-resolution, 24-bit color version of these images. The dataset tested includes 2,413 still facial images, representing 856 individuals. The FERET database has been used by more than 460 research groups and is managed by the National Institute of Standards and Technology (NIST).

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  • Mathematics of neural networks in machine learning

    Mathematics of neural networks in machine learning

    An artificial neural network (ANN) or neural network combines biological principles with advanced statistics to solve problems in domains such as pattern recognition and game-play. ANNs adopt the basic model of neuron analogues connected to each other in a variety of ways. == Structure == === Neuron === A neuron with label j {\displaystyle j} receiving an input p j ( t ) {\displaystyle p_{j}(t)} from predecessor neurons consists of the following components: an activation a j ( t ) {\displaystyle a_{j}(t)} , the neuron's state, depending on a discrete time parameter, an optional threshold θ j {\displaystyle \theta _{j}} , which stays fixed unless changed by learning, an activation function f {\displaystyle f} that computes the new activation at a given time t + 1 {\displaystyle t+1} from a j ( t ) {\displaystyle a_{j}(t)} , θ j {\displaystyle \theta _{j}} and the net input p j ( t ) {\displaystyle p_{j}(t)} giving rise to the relation a j ( t + 1 ) = f ( a j ( t ) , p j ( t ) , θ j ) , {\displaystyle a_{j}(t+1)=f(a_{j}(t),p_{j}(t),\theta _{j}),} and an output function f out {\displaystyle f_{\text{out}}} computing the output from the activation o j ( t ) = f out ( a j ( t ) ) . {\displaystyle o_{j}(t)=f_{\text{out}}(a_{j}(t)).} Often the output function is simply the identity function. An input neuron has no predecessor but serves as input interface for the whole network. Similarly an output neuron has no successor and thus serves as output interface of the whole network. === Propagation function === The propagation function computes the input p j ( t ) {\displaystyle p_{j}(t)} to the neuron j {\displaystyle j} from the outputs o i ( t ) {\displaystyle o_{i}(t)} and typically has the form p j ( t ) = ∑ i o i ( t ) w i j . {\displaystyle p_{j}(t)=\sum _{i}o_{i}(t)w_{ij}.} === Bias === A bias term can be added, changing the form to the following: p j ( t ) = ∑ i o i ( t ) w i j + w 0 j , {\displaystyle p_{j}(t)=\sum _{i}o_{i}(t)w_{ij}+w_{0j},} where w 0 j {\displaystyle w_{0j}} is a bias. == Neural networks as functions == Neural network models can be viewed as defining a function that takes an input (observation) and produces an output (decision) f : X → Y {\displaystyle \textstyle f:X\rightarrow Y} or a distribution over X {\displaystyle \textstyle X} or both X {\displaystyle \textstyle X} and Y {\displaystyle \textstyle Y} . Sometimes models are intimately associated with a particular learning rule. A common use of the phrase "ANN model" is really the definition of a class of such functions (where members of the class are obtained by varying parameters, connection weights, or specifics of the architecture such as the number of neurons, number of layers or their connectivity). Mathematically, a neuron's network function f ( x ) {\displaystyle \textstyle f(x)} is defined as a composition of other functions g i ( x ) {\displaystyle \textstyle g_{i}(x)} , that can further be decomposed into other functions. This can be conveniently represented as a network structure, with arrows depicting the dependencies between functions. A widely used type of composition is the nonlinear weighted sum, where f ( x ) = K ( ∑ i w i g i ( x ) ) {\displaystyle \textstyle f(x)=K\left(\sum _{i}w_{i}g_{i}(x)\right)} , where K {\displaystyle \textstyle K} (commonly referred to as the activation function) is some predefined function, such as the hyperbolic tangent, sigmoid function, softmax function, or rectifier function. The important characteristic of the activation function is that it provides a smooth transition as input values change, i.e. a small change in input produces a small change in output. The following refers to a collection of functions g i {\displaystyle \textstyle g_{i}} as a vector g = ( g 1 , g 2 , … , g n ) {\displaystyle \textstyle g=(g_{1},g_{2},\ldots ,g_{n})} . This figure depicts such a decomposition of f {\displaystyle \textstyle f} , with dependencies between variables indicated by arrows. These can be interpreted in two ways. The first view is the functional view: the input x {\displaystyle \textstyle x} is transformed into a 3-dimensional vector h {\displaystyle \textstyle h} , which is then transformed into a 2-dimensional vector g {\displaystyle \textstyle g} , which is finally transformed into f {\displaystyle \textstyle f} . This view is most commonly encountered in the context of optimization. The second view is the probabilistic view: the random variable F = f ( G ) {\displaystyle \textstyle F=f(G)} depends upon the random variable G = g ( H ) {\displaystyle \textstyle G=g(H)} , which depends upon H = h ( X ) {\displaystyle \textstyle H=h(X)} , which depends upon the random variable X {\displaystyle \textstyle X} . This view is most commonly encountered in the context of graphical models. The two views are largely equivalent. In either case, for this particular architecture, the components of individual layers are independent of each other (e.g., the components of g {\displaystyle \textstyle g} are independent of each other given their input h {\displaystyle \textstyle h} ). This naturally enables a degree of parallelism in the implementation. Networks such as the previous one are commonly called feedforward, because their graph is a directed acyclic graph. Networks with cycles are commonly called recurrent. Such networks are commonly depicted in the manner shown at the top of the figure, where f {\displaystyle \textstyle f} is shown as dependent upon itself. However, an implied temporal dependence is not shown. == Backpropagation == Backpropagation training algorithms fall into three categories: steepest descent (with variable learning rate and momentum, resilient backpropagation); quasi-Newton (Broyden–Fletcher–Goldfarb–Shanno, one step secant); Levenberg–Marquardt and conjugate gradient (Fletcher–Reeves update, Polak–Ribiére update, Powell–Beale restart, scaled conjugate gradient). === Algorithm === Let N {\displaystyle N} be a network with e {\displaystyle e} connections, m {\displaystyle m} inputs and n {\displaystyle n} outputs. Below, x 1 , x 2 , … {\displaystyle x_{1},x_{2},\dots } denote vectors in R m {\displaystyle \mathbb {R} ^{m}} , y 1 , y 2 , … {\displaystyle y_{1},y_{2},\dots } vectors in R n {\displaystyle \mathbb {R} ^{n}} , and w 0 , w 1 , w 2 , … {\displaystyle w_{0},w_{1},w_{2},\ldots } vectors in R e {\displaystyle \mathbb {R} ^{e}} . These are called inputs, outputs and weights, respectively. The network corresponds to a function y = f N ( w , x ) {\displaystyle y=f_{N}(w,x)} which, given a weight w {\displaystyle w} , maps an input x {\displaystyle x} to an output y {\displaystyle y} . In supervised learning, a sequence of training examples ( x 1 , y 1 ) , … , ( x p , y p ) {\displaystyle (x_{1},y_{1}),\dots ,(x_{p},y_{p})} produces a sequence of weights w 0 , w 1 , … , w p {\displaystyle w_{0},w_{1},\dots ,w_{p}} starting from some initial weight w 0 {\displaystyle w_{0}} , usually chosen at random. These weights are computed in turn: first compute w i {\displaystyle w_{i}} using only ( x i , y i , w i − 1 ) {\displaystyle (x_{i},y_{i},w_{i-1})} for i = 1 , … , p {\displaystyle i=1,\dots ,p} . The output of the algorithm is then w p {\displaystyle w_{p}} , giving a new function x ↦ f N ( w p , x ) {\displaystyle x\mapsto f_{N}(w_{p},x)} . The computation is the same in each step, hence only the case i = 1 {\displaystyle i=1} is described. w 1 {\displaystyle w_{1}} is calculated from ( x 1 , y 1 , w 0 ) {\displaystyle (x_{1},y_{1},w_{0})} by considering a variable weight w {\displaystyle w} and applying gradient descent to the function w ↦ E ( f N ( w , x 1 ) , y 1 ) {\displaystyle w\mapsto E(f_{N}(w,x_{1}),y_{1})} to find a local minimum, starting at w = w 0 {\displaystyle w=w_{0}} . This makes w 1 {\displaystyle w_{1}} the minimizing weight found by gradient descent. == Learning pseudocode == To implement the algorithm above, explicit formulas are required for the gradient of the function w ↦ E ( f N ( w , x ) , y ) {\displaystyle w\mapsto E(f_{N}(w,x),y)} where the function is E ( y , y ′ ) = | y − y ′ | 2 {\displaystyle E(y,y')=|y-y'|^{2}} . The learning algorithm can be divided into two phases: propagation and weight update. === Propagation === Propagation involves the following steps: Propagation forward through the network to generate the output value(s) Calculation of the cost (error term) Propagation of the output activations back through the network using the training pattern target to generate the deltas (the difference between the targeted and actual output values) of all output and hidden neurons. === Weight update === For each weight: Multiply the weight's output delta and input activation to find the gradient of the weight. Subtract the ratio (percentage) of the weight's gradient from the weight. The learning rate is the ratio (percentage) that influences the speed and quality of learning. The greater the ratio, the faster the neuron trains, but the lower the ratio, the more accurat

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  • Slopaganda

    Slopaganda

    Slopaganda is a portmanteau of "AI slop" and "propaganda", referring to AI-generated content designed to manipulate beliefs, emotions, and political decision-making at scale. The term is credited to Michał Klincewicz, an assistant professor in the Department of Computational Cognitive Science at Tilburg University, in 2025. == Definition == Slopaganda is distinguished from traditional propaganda by three features: scale, scope, and speed. Generative AI makes it possible to produce large volumes of content quickly and at low cost, allows for highly personalised and targeted messaging to specific sub-audiences, and leverages the hyper-connectivity of social networks to accelerate dissemination beyond what conventional media could achieve. Unlike traditional propaganda, which delivers a uniform message to all recipients, slopaganda can be micro-targeted — tailored to individuals based on estimated prior beliefs to reinforce political biases or emotional associations. The authors note that it need not aim at literal deception: much slopaganda is expressive rather than truth-apt, designed to create emotional associations rather than false factual beliefs. == Relation to AI slop == Slopaganda is a subset of AI slop — low-quality, mass-produced AI-generated content — distinguished by intent. Where AI slop may be produced indifferently for commercial or engagement-farming purposes, slopaganda is deployed with a deliberate political or ideological goal. == Notable examples == Examples discussed by the term's originators include Donald Trump's prolific use of AI in Truth Social posts and Iranian Lego-themed music videos. AI-generated videos posted by the White House mixing real military footage with clips from films and video games; and deepfake audio imitating political candidates during the 2024 US presidential campaign have also been given the label slopaganda.

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  • Elastic map

    Elastic map

    Elastic maps provide a tool for nonlinear dimensionality reduction. By their construction, they are a system of elastic springs embedded in the data space. This system approximates a low-dimensional manifold. The elastic coefficients of this system allow the switch from completely unstructured k-means clustering (zero elasticity) to the estimators located closely to linear PCA manifolds (for high bending and low stretching modules). With some intermediate values of the elasticity coefficients, this system effectively approximates non-linear principal manifolds. This approach is based on a mechanical analogy between principal manifolds, that are passing through "the middle" of the data distribution, and elastic membranes and plates. The method was developed by A.N. Gorban, A.Y. Zinovyev and A.A. Pitenko in 1996–1998. == Energy of elastic map == Let S {\displaystyle {\mathcal {S}}} be a data set in a finite-dimensional Euclidean space. Elastic map is represented by a set of nodes w j {\displaystyle {\bf {w}}_{j}} in the same space. Each datapoint s ∈ S {\displaystyle s\in {\mathcal {S}}} has a host node, namely the closest node w j {\displaystyle {\bf {w}}_{j}} (if there are several closest nodes then one takes the node with the smallest number). The data set S {\displaystyle {\mathcal {S}}} is divided into classes K j = { s | w j is a host of s } {\displaystyle K_{j}=\{s\ |\ {\bf {w}}_{j}{\mbox{ is a host of }}s\}} . The approximation energy D is the distortion D = 1 2 ∑ j = 1 k ∑ s ∈ K j ‖ s − w j ‖ 2 {\displaystyle D={\frac {1}{2}}\sum _{j=1}^{k}\sum _{s\in K_{j}}\|s-{\bf {w}}_{j}\|^{2}} , which is the energy of the springs with unit elasticity which connect each data point with its host node. It is possible to apply weighting factors to the terms of this sum, for example to reflect the standard deviation of the probability density function of any subset of data points { s i } {\displaystyle \{s_{i}\}} . On the set of nodes an additional structure is defined. Some pairs of nodes, ( w i , w j ) {\displaystyle ({\bf {w}}_{i},{\bf {w}}_{j})} , are connected by elastic edges. Call this set of pairs E {\displaystyle E} . Some triplets of nodes, ( w i , w j , w k ) {\displaystyle ({\bf {w}}_{i},{\bf {w}}_{j},{\bf {w}}_{k})} , form bending ribs. Call this set of triplets G {\displaystyle G} . The stretching energy is U E = 1 2 λ ∑ ( w i , w j ) ∈ E ‖ w i − w j ‖ 2 {\displaystyle U_{E}={\frac {1}{2}}\lambda \sum _{({\bf {w}}_{i},{\bf {w}}_{j})\in E}\|{\bf {w}}_{i}-{\bf {w}}_{j}\|^{2}} , The bending energy is U G = 1 2 μ ∑ ( w i , w j , w k ) ∈ G ‖ w i − 2 w j + w k ‖ 2 {\displaystyle U_{G}={\frac {1}{2}}\mu \sum _{({\bf {w}}_{i},{\bf {w}}_{j},{\bf {w}}_{k})\in G}\|{\bf {w}}_{i}-2{\bf {w}}_{j}+{\bf {w}}_{k}\|^{2}} , where λ {\displaystyle \lambda } and μ {\displaystyle \mu } are the stretching and bending moduli respectively. The stretching energy is sometimes referred to as the membrane, while the bending energy is referred to as the thin plate term. For example, on the 2D rectangular grid the elastic edges are just vertical and horizontal edges (pairs of closest vertices) and the bending ribs are the vertical or horizontal triplets of consecutive (closest) vertices. The total energy of the elastic map is thus U = D + U E + U G . {\displaystyle U=D+U_{E}+U_{G}.} The position of the nodes { w j } {\displaystyle \{{\bf {w}}_{j}\}} is determined by the mechanical equilibrium of the elastic map, i.e. its location is such that it minimizes the total energy U {\displaystyle U} . == Expectation-maximization algorithm == For a given splitting of dataset S {\displaystyle {\mathcal {S}}} in classes K j {\displaystyle K_{j}} , minimization of the quadratic functional U {\displaystyle U} is a linear problem with the sparse matrix of coefficients. Therefore, similar to principal component analysis or k-means, a splitting method is used: For given { w j } {\displaystyle \{{\bf {w}}_{j}\}} find { K j } {\displaystyle \{K_{j}\}} ; For given { K j } {\displaystyle \{K_{j}\}} minimize U {\displaystyle U} and find { w j } {\displaystyle \{{\bf {w}}_{j}\}} ; If no change, terminate. This expectation-maximization algorithm guarantees a local minimum of U {\displaystyle U} . For improving the approximation various additional methods are proposed. For example, the softening strategy is used. This strategy starts with a rigid grids (small length, small bending and large elasticity modules λ {\displaystyle \lambda } and μ {\displaystyle \mu } coefficients) and finishes with soft grids (small λ {\displaystyle \lambda } and μ {\displaystyle \mu } ). The training goes in several epochs, each epoch with its own grid rigidness. Another adaptive strategy is growing net: one starts from a small number of nodes and gradually adds new nodes. Each epoch goes with its own number of nodes. == Applications == Most important applications of the method and free software are in bioinformatics for exploratory data analysis and visualisation of multidimensional data, for data visualisation in economics, social and political sciences, as an auxiliary tool for data mapping in geographic informational systems and for visualisation of data of various nature. The method is applied in quantitative biology for reconstructing the curved surface of a tree leaf from a stack of light microscopy images. This reconstruction is used for quantifying the geodesic distances between trichomes and their patterning, which is a marker of the capability of a plant to resist to pathogenes. Recently, the method is adapted as a support tool in the decision process underlying the selection, optimization, and management of financial portfolios. The method of elastic maps has been systematically tested and compared with several machine learning methods on the applied problem of identification of the flow regime of a gas-liquid flow in a pipe. There are various regimes: Single phase water or air flow, Bubbly flow, Bubbly-slug flow, Slug flow, Slug-churn flow, Churn flow, Churn-annular flow, and Annular flow. The simplest and most common method used to identify the flow regime is visual observation. This approach is, however, subjective and unsuitable for relatively high gas and liquid flow rates. Therefore, the machine learning methods are proposed by many authors. The methods are applied to differential pressure data collected during a calibration process. The method of elastic maps provided a 2D map, where the area of each regime is represented. The comparison with some other machine learning methods is presented in Table 1 for various pipe diameters and pressure. Here, ANN stands for the backpropagation artificial neural networks, SVM stands for the support vector machine, SOM for the self-organizing maps. The hybrid technology was developed for engineering applications. In this technology, elastic maps are used in combination with Principal Component Analysis (PCA), Independent Component Analysis (ICA) and backpropagation ANN. The textbook provides a systematic comparison of elastic maps and self-organizing maps (SOMs) in applications to economic and financial decision-making.

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  • Spiking neural network

    Spiking neural network

    Spiking neural networks (SNNs) are artificial neural networks (ANN) that mimic natural neural networks. These models leverage timing of discrete spikes as the main information carrier. In addition to neuronal and synaptic state, SNNs incorporate the concept of time into their operating model. The idea is that neurons in the SNN do not transmit information at each propagation cycle (as it happens with typical multi-layer perceptron networks), but rather transmit information only when a membrane potential—an intrinsic quality of the neuron related to its membrane electrical charge—reaches a specific value, called the threshold. When the membrane potential reaches the threshold, the neuron fires, and generates a signal that travels to other neurons which, in turn, increase or decrease their potentials in response to this signal. A neuron model that fires at the moment of threshold crossing is also called a spiking neuron model. While spike rates can be considered the analogue of the variable output of a traditional ANN, neurobiology research indicated that high speed processing cannot be performed solely through a rate-based scheme. For example humans can perform an image recognition task requiring no more than 10ms of processing time per neuron through the successive layers (going from the retina to the temporal lobe). This time window is too short for rate-based encoding. The precise spike timings in a small set of spiking neurons also has a higher information coding capacity compared with a rate-based approach. The most prominent spiking neuron model is the leaky integrate-and-fire model. In that model, the momentary activation level (modeled as a differential equation) is normally considered to be the neuron's state, with incoming spikes pushing this value higher or lower, until the state eventually either decays or—if the firing threshold is reached—the neuron fires. After firing, the state variable is reset to a lower value. Various decoding methods exist for interpreting the outgoing spike train as a real-value number, relying on either the frequency of spikes (rate-code), the time-to-first-spike after stimulation, or the interval between spikes. == History == Many multi-layer artificial neural networks are fully connected, receiving input from every neuron in the previous layer and signalling every neuron in the subsequent layer. Although these networks have achieved breakthroughs, they do not match biological networks and do not mimic neurons. The biology-inspired Hodgkin–Huxley model of a spiking neuron was proposed in 1952. This model described how action potentials are initiated and propagated. Communication between neurons, which requires the exchange of chemical neurotransmitters in the synaptic gap, is described in models such as the integrate-and-fire model, FitzHugh–Nagumo model (1961–1962), and Hindmarsh–Rose model (1984). The leaky integrate-and-fire model (or a derivative) is commonly used as it is easier to compute than Hodgkin–Huxley. While the notion of an artificial spiking neural network became popular only in the twenty-first century, studies between 1980 and 1995 supported the concept. The first models of this type of ANN appeared to simulate non-algorithmic intelligent information processing systems. However, the notion of the spiking neural network as a mathematical model was first worked on in the early 1970s. As of 2019 SNNs lagged behind ANNs in accuracy, but the gap is decreasing, and has vanished on some tasks. == Underpinnings == Information in the brain is represented as action potentials (neuron spikes), which may group into spike trains or coordinated waves. A fundamental question of neuroscience is to determine whether neurons communicate by a rate or temporal code. Temporal coding implies that a single spiking neuron can replace hundreds of hidden units on a conventional neural net. SNNs define a neuron's current state as its potential (possibly modeled as a differential equation). An input pulse causes the potential to rise and then gradually decline. Encoding schemes can interpret these pulse sequences as a number, considering pulse frequency and pulse interval. Using the precise time of pulse occurrence, a neural network can consider more information and offer better computing properties. SNNs compute in the continuous domain. Such neurons test for activation only when their potentials reach a certain value. When a neuron is activated, it produces a signal that is passed to connected neurons, accordingly raising or lowering their potentials. The SNN approach produces a continuous output instead of the binary output of traditional ANNs. Pulse trains are not easily interpretable, hence the need for encoding schemes. However, a pulse train representation may be more suited for processing spatiotemporal data (or real-world sensory data classification). SNNs connect neurons only to nearby neurons so that they process input blocks separately (similar to CNN using filters). They consider time by encoding information as pulse trains so as not to lose information. This avoids the complexity of a recurrent neural network (RNN). Impulse neurons are more powerful computational units than traditional artificial neurons. SNNs are theoretically more powerful than so called "second-generation networks" defined as ANNs "based on computational units that apply activation function with a continuous set of possible output values to a weighted sum (or polynomial) of the inputs"; however, SNN training issues and hardware requirements limit their use. Although unsupervised biologically inspired learning methods are available such as Hebbian learning and STDP, no effective supervised training method is suitable for SNNs that can provide better performance than second-generation networks. Spike-based activation of SNNs is not differentiable, thus gradient descent-based backpropagation (BP) is not available. SNNs have much larger computational costs for simulating realistic neural models than traditional ANNs. Pulse-coupled neural networks (PCNN) are often confused with SNNs. A PCNN can be seen as a kind of SNN. Researchers are actively working on various topics. The first concerns differentiability. The expressions for both the forward- and backward-learning methods contain the derivative of the neural activation function which is not differentiable because a neuron's output is either 1 when it spikes, and 0 otherwise. This all-or-nothing behavior disrupts gradients and makes these neurons unsuitable for gradient-based optimization. Approaches to resolving it include: resorting to entirely biologically inspired local learning rules for the hidden units translating conventionally trained "rate-based" NNs to SNNs smoothing the network model to be continuously differentiable defining an SG (Surrogate Gradient) as a continuous relaxation of the real gradients The second concerns the optimization algorithm. Standard BP can be expensive in terms of computation, memory, and communication and may be poorly suited to the hardware that implements it (e.g., a computer, brain, or neuromorphic device). Incorporating additional neuron dynamics such as Spike Frequency Adaptation (SFA) is a notable advance, enhancing efficiency and computational power. These neurons sit between biological complexity and computational complexity. Originating from biological insights, SFA offers significant computational benefits by reducing power usage, especially in cases of repetitive or intense stimuli. This adaptation improves signal/noise clarity and introduces an elementary short-term memory at the neuron level, which in turn, improves accuracy and efficiency. This was mostly achieved using compartmental neuron models. The simpler versions are of neuron models with adaptive thresholds, are an indirect way of achieving SFA. It equips SNNs with improved learning capabilities, even with constrained synaptic plasticity, and elevates computational efficiency. This feature lessens the demand on network layers by decreasing the need for spike processing, thus lowering computational load and memory access time—essential aspects of neural computation. Moreover, SNNs utilizing neurons capable of SFA achieve levels of accuracy that rival those of conventional ANNs, while also requiring fewer neurons for comparable tasks. This efficiency streamlines the computational workflow and conserves space and energy, while maintaining technical integrity. High-performance deep spiking neural networks can operate with 0.3 spikes per neuron. == Applications == SNNs can in principle be applied to the same applications as traditional ANNs. In addition, SNNs can model the central nervous system of biological organisms, such as an insect seeking food without prior knowledge of the environment. Due to their relative realism, they can be used to study biological neural circuits. Starting with a hypothesis about the topology of a biological neuronal circuit and its functi

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  • Bondy's theorem

    Bondy's theorem

    In mathematics, Bondy's theorem is a bound on the number of elements needed to distinguish the sets in a family of sets from each other. It belongs to the field of combinatorics, and is named after John Adrian Bondy, who published it in 1972. == Statement == The theorem is as follows: Let X be a set with n elements and let A1, A2, ..., An be distinct subsets of X. Then there exists a subset S of X with n − 1 elements such that the sets Ai ∩ S are all distinct. In other words, if we have a 0-1 matrix with n rows and n columns such that each row is distinct, we can remove one column such that the rows of the resulting n × (n − 1) matrix are distinct. == Example == Consider the 4 × 4 matrix [ 1 1 0 1 0 1 0 1 0 0 1 1 0 1 1 0 ] {\displaystyle {\begin{bmatrix}1&1&0&1\\0&1&0&1\\0&0&1&1\\0&1&1&0\end{bmatrix}}} where all rows are pairwise distinct. If we delete, for example, the first column, the resulting matrix [ 1 0 1 1 0 1 0 1 1 1 1 0 ] {\displaystyle {\begin{bmatrix}1&0&1\\1&0&1\\0&1&1\\1&1&0\end{bmatrix}}} no longer has this property: the first row is identical to the second row. Nevertheless, by Bondy's theorem we know that we can always find a column that can be deleted without introducing any identical rows. In this case, we can delete the third column: all rows of the 3 × 4 matrix [ 1 1 1 0 1 1 0 0 1 0 1 0 ] {\displaystyle {\begin{bmatrix}1&1&1\\0&1&1\\0&0&1\\0&1&0\end{bmatrix}}} are distinct. Another possibility would have been deleting the fourth column. == Learning theory application == From the perspective of computational learning theory, Bondy's theorem can be rephrased as follows: Let C be a concept class over a finite domain X. Then there exists a subset S of X with the size at most |C| − 1 such that S is a witness set for every concept in C. This implies that every finite concept class C has its teaching dimension bounded by |C| − 1.

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  • Landmark point

    Landmark point

    In morphometrics, landmark point or shortly landmark is a point in a shape object in which correspondences between and within the populations of the object are preserved. In other disciplines, landmarks may be known as vertices, anchor points, control points, sites, profile points, 'sampling' points, nodes, markers, fiducial markers, etc. Landmarks can be defined either manually by experts or automatically by a computer program. There are three basic types of landmarks: anatomical landmarks, mathematical landmarks or pseudo-landmarks. An anatomical landmark is a biologically-meaningful point in an organism. Usually experts define anatomical points to ensure their correspondences within the same species. Examples of anatomical landmark in shape of a skull are the eye corner, tip of the nose, jaw, etc. Anatomical landmarks determine homologous parts of an organism, which share a common ancestry. Mathematical landmarks are points in a shape that are located according to some mathematical or geometrical property, for instance, a high curvature point or an extreme point. A computer program usually determines mathematical landmarks used for an automatic pattern recognition. Pseudo-landmarks are constructed points located between anatomical or mathematical landmarks. A typical example is an equally spaced set of points between two anatomical landmarks to get more sample points from a shape. Pseudo-landmarks are useful during shape matching, when the matching process requires a large number of points.

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  • Radial basis function

    Radial basis function

    In mathematics a radial basis function (RBF) is a real-valued function φ {\textstyle \varphi } whose value depends only on the distance between the input and some fixed point, either the origin, so that φ ( x ) = φ ^ ( ‖ x ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} \right\|)} , or some other fixed point c {\textstyle \mathbf {c} } , called a center, so that φ ( x ) = φ ^ ( ‖ x − c ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} -\mathbf {c} \right\|)} . Any function φ {\textstyle \varphi } that satisfies the property φ ( x ) = φ ^ ( ‖ x ‖ ) {\textstyle \varphi (\mathbf {x} )={\hat {\varphi }}(\left\|\mathbf {x} \right\|)} is a radial function. The distance is usually Euclidean distance, although other metrics are sometimes used. They are often used as a collection { φ k } k {\displaystyle \{\varphi _{k}\}_{k}} which forms a basis for some function space of interest, hence the name. Sums of radial basis functions are typically used to approximate given functions. This approximation process can also be interpreted as a simple kind of neural network; this was the context in which they were originally applied to machine learning, in work by David Broomhead and David Lowe in 1988, which stemmed from Michael J. D. Powell's seminal research from 1977. RBFs are also used as a kernel in support vector classification. The technique has proven effective and flexible enough that radial basis functions are now applied in a variety of engineering applications. == Definition == A radial function is a function φ : [ 0 , ∞ ) → R {\textstyle \varphi :[0,\infty )\to \mathbb {R} } . When paired with a norm ‖ ⋅ ‖ : V → [ 0 , ∞ ) {\textstyle \|\cdot \|:V\to [0,\infty )} on a vector space, a function of the form φ c = φ ( ‖ x − c ‖ ) {\textstyle \varphi _{\mathbf {c} }=\varphi (\|\mathbf {x} -\mathbf {c} \|)} is said to be a radial kernel centered at c ∈ V {\textstyle \mathbf {c} \in V} . A radial function and the associated radial kernels are said to be radial basis functions if, for any finite set of nodes { x k } k = 1 n ⊆ V {\displaystyle \{\mathbf {x} _{k}\}_{k=1}^{n}\subseteq V} , all of the following conditions are true: === Examples === Commonly used types of radial basis functions include (writing r = ‖ x − x i ‖ {\textstyle r=\left\|\mathbf {x} -\mathbf {x} _{i}\right\|} and using ε {\textstyle \varepsilon } to indicate a shape parameter that can be used to scale the input of the radial kernel): == Approximation == Radial basis functions are typically used to build up function approximations of the form where the approximating function y ( x ) {\textstyle y(\mathbf {x} )} is represented as a sum of N {\displaystyle N} radial basis functions, each associated with a different center x i {\textstyle \mathbf {x} _{i}} , and weighted by an appropriate coefficient w i . {\textstyle w_{i}.} The weights w i {\textstyle w_{i}} can be estimated using the matrix methods of linear least squares, because the approximating function is linear in the weights w i {\textstyle w_{i}} . Approximation schemes of this kind have been particularly used in time series prediction and control of nonlinear systems exhibiting sufficiently simple chaotic behaviour and 3D reconstruction in computer graphics (for example, hierarchical RBF and Pose Space Deformation). == RBF Network == The sum can also be interpreted as a rather simple single-layer type of artificial neural network called a radial basis function network, with the radial basis functions taking on the role of the activation functions of the network. It can be shown that any continuous function on a compact interval can in principle be interpolated with arbitrary accuracy by a sum of this form, if a sufficiently large number N {\textstyle N} of radial basis functions is used. The approximant y ( x ) {\textstyle y(\mathbf {x} )} is differentiable with respect to the weights w i {\textstyle w_{i}} . The weights could thus be learned using any of the standard iterative methods for neural networks. Using radial basis functions in this manner yields a reasonable interpolation approach provided that the fitting set has been chosen such that it covers the entire range systematically (equidistant data points are ideal). However, without a polynomial term that is orthogonal to the radial basis functions, estimates outside the fitting set tend to perform poorly. == RBFs for PDEs == Radial basis functions are used to approximate functions and so can be used to discretize and numerically solve Partial Differential Equations (PDEs). This was first done in 1990 by E. J. Kansa who developed the first RBF based numerical method. It is called the Kansa method and was used to solve the elliptic Poisson equation and the linear advection-diffusion equation. The function values at points x {\displaystyle \mathbf {x} } in the domain are approximated by the linear combination of RBFs: The derivatives are approximated as such: where N {\displaystyle N} are the number of points in the discretized domain, d {\displaystyle d} the dimension of the domain and λ {\displaystyle \lambda } the scalar coefficients that are unchanged by the differential operator. Different numerical methods based on Radial Basis Functions were developed thereafter. Some methods are the RBF-FD method, the RBF-QR method and the RBF-PUM method.

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  • Minimum Population Search

    Minimum Population Search

    In evolutionary computation, Minimum Population Search (MPS) is a computational method that optimizes a problem by iteratively trying to improve a set of candidate solutions with regard to a given measure of quality. It solves a problem by evolving a small population of candidate solutions by means of relatively simple arithmetical operations. MPS is a metaheuristic as it makes few or no assumptions about the problem being optimized and can search very large spaces of candidate solutions. For problems where finding the precise global optimum is less important than finding an acceptable local optimum in a fixed amount of time, using a metaheuristic such as MPS may be preferable to alternatives such as brute-force search or gradient descent. MPS is used for multidimensional real-valued functions but does not use the gradient of the problem being optimized, which means MPS does not require for the optimization problem to be differentiable as is required by classic optimization methods such as gradient descent and quasi-newton methods. MPS can therefore also be used on optimization problems that are not even continuous, are noisy, change over time, etc. == Background == In a similar way to Differential evolution, MPS uses difference vectors between the members of the population in order to generate new solutions. It attempts to provide an efficient use of function evaluations by maintaining a small population size. If the population size is smaller than the dimensionality of the search space, then the solutions generated through difference vectors will be constrained to the n − 1 {\displaystyle n-1} dimensional hyperplane. A smaller population size will lead to a more restricted subspace. With a population size equal to the dimensionality of the problem ( n = d ) {\displaystyle (n=d)} , the “line/hyperplane points” in MPS will be generated within a d − 1 {\displaystyle d-1} dimensional hyperplane. Taking a step orthogonal to this hyperplane will allow the search process to cover all the dimensions of the search space. Population size is a fundamental parameter in the performance of population-based heuristics. Larger populations promote exploration, but they also allow fewer generations, and this can reduce the chance of convergence. Searching with a small population can increase the chances of convergence and the efficient use of function evaluations, but it can also induce the risk of premature convergence. If the risk of premature convergence can be avoided, then a population-based heuristic could benefit from the efficiency and faster convergence rate of a smaller population. To avoid premature convergence, it is important to have a diversified population. By including techniques for explicitly increasing diversity and exploration, it is possible to have smaller populations with less risk of premature convergence. === Thresheld Convergence === Thresheld Convergence (TC) is a diversification technique which attempts to separate the processes of exploration and exploitation. TC uses a “threshold” function to establish a minimum search step, and managing this step makes it possible to influence the transition from exploration to exploitation, convergence is thus “held” back until the last stages of the search process. The goal of a controlled transition is to avoid an early concentration of the population around a few search regions and avoid the loss of diversity which can cause premature convergence. Thresheld Convergence has been successfully applied to several population-based metaheuristics such as Particle Swarm Optimization, Differential evolution, Evolution strategies, Simulated annealing and Estimation of Distribution Algorithms. The ideal case for Thresheld Convergence is to have one sample solution from each attraction basin, and for each sample solution to have the same relative fitness with respect to its local optimum. Enforcing a minimum step aims to achieve this ideal case. In MPS Thresheld Convergence is specifically used to preserve diversity and avoid premature convergence by establishing a minimum search step. By disallowing new solutions which are too close to members of the current population, TC forces a strong exploration during the early stages of the search while preserving the diversity of the (small) population. == Algorithm == A basic variant of the MPS algorithm works by having a population of size equal to the dimension of the problem. New solutions are generated by exploring the hyperplane defined by the current solutions (by means of difference vectors) and performing an additional orthogonal step in order to avoid getting caught in this hyperplane. The step sizes are controlled by the Thresheld Convergence technique, which gradually reduces step sizes as the search process advances. An outline for the algorithm is given below: Generate the first initial population. Allowing these solutions to lie near the bounds of the search space generally gives good results: s k = ( r s 1 ∗ b o u n d 1 / 2 , r s 2 ∗ b o u n d 2 / 2 , . . . , r s n ∗ b o u n d n / 2 ) {\displaystyle s_{k}=(rs_{1}bound_{1}/2,rs_{2}bound_{2}/2,...,rs_{n}bound_{n}/2)} where s k {\displaystyle s_{k}} is the k {\displaystyle k} -th population member, r s i {\displaystyle rs_{i}} are random numbers which can be −1 or 1, and the b o u n d i {\displaystyle bound_{i}} are the lower and upper bounds on each dimension. While a stop condition is not reached: Update threshold convergence values ( m i n _ s t e p {\displaystyle min\_step} and m a x _ s t e p {\displaystyle max\_step} ) Calculate the centroid of the current population ( x c {\displaystyle x_{c}} ) For each member of the population ( x i {\displaystyle x_{i}} ), generate a new offspring as follows: Uniformly generate a scaling factor ( F i {\displaystyle F_{i}} ) between − m a x _ s t e p {\displaystyle -max\_step} and m a x _ s t e p {\displaystyle max\_step} Generate a vector ( x o {\displaystyle x_{o}} ) orthogonal to the difference vector between x i {\displaystyle x_{i}} and x c {\displaystyle x_{c}} Calculate a scaling factor for the orthogonal vector: m i n _ o r t h = s q r t ( m a x ( m i n _ s t e p 2 − F i 2 , 0 ) ) {\displaystyle min\_orth=sqrt(max(min\_step^{2}-F_{i}^{2},0))} m a x _ o r t h = s q r t ( m a x ( m a x _ s t e p 2 − F i 2 , 0 ) ) {\displaystyle max\_orth=sqrt(max(max\_step^{2}-F_{i}^{2},0))} o r t h _ s t e p = u n i f o r m ( m i n _ o r t h , m a x _ o r t h ) {\displaystyle orth\_step=uniform(min\_orth,max\_orth)} Generate the new solution by adding the difference and the orthogonal vectors to the original solution n e w _ s o l u t i o n = x i + F i ∗ ( x i − x c ) ∗ o r t h _ s t e p ∗ x o {\displaystyle new\_solution=x_{i}+F_{i}(x_{i}-x_{c})orth\_stepx_{o}} Pick the best members between the old population and the new one by discarding the least fit members. Return the single best solution or the best population found as the final result.

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  • Prescription monitoring program

    Prescription monitoring program

    In the United States, prescription monitoring programs (PMPs) or prescription drug monitoring programs (PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs. PMPs are meant to help prevent adverse drug-related events such as opioid overdoses, drug diversion, and substance abuse by decreasing the amount and/or frequency of opioid prescribing, and by identifying those patients who are obtaining prescriptions from multiple providers (i.e., "doctor shopping") or those physicians overprescribing opioids. Most US health care workers support the idea of PMPs, which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments. The database, whose use is required by State law, typically requires prescribers and pharmacies dispensing controlled substances to register with their respective state PMPs and (for pharmacies and providers who dispense from their offices) to report the dispensation of such prescriptions to an electronic online database. The majority of PMPs are authorized to notify law enforcement agencies or licensing boards or physicians when a prescriber, or patients receiving prescriptions, exceed thresholds established by the state or prescription recipient exceeds thresholds established by the State. All states have implemented PDMPs, although evidence for the effectiveness of these programs is mixed. While prescription of opioids has decreased with PMP use, overdose deaths in many states have actually increased, with those states sharing data with neighboring jurisdictions or requiring reporting of more drugs experiencing highest increases in deaths. This may be because those declined opioid prescriptions turn to street drugs, whose potency and contaminants carry greater overdose risk. == History == Prescription drug monitoring programs, or PDMPs, are an example of one initiative proposed to alleviate effects of the opioid crisis. The programs are designed to restrict prescription drug abuse by limiting a patient's ability to obtain similar prescriptions from multiple providers (i.e. “doctor shopping”) and reducing diversion of controlled substances. This is meant to reduce risk of fatal overdose caused by high doses of opioids or interactions between opioids and benzodiazepenes, and to enable better decision making on the part of healthcare providers who may be unaware of a patient's prescription drug use, history or other prescriptions. PDMPs have been implemented in state legislations since 1939 in California, a time before electronic medical records, though implementation rose alongside increased awareness of overprescribing of opioids and overdose. A later New York state program was struck down by the U.S. Supreme Court in Whalen v. Roe. But, by 2019, 49 states, the District of Columbia, and Guam had enacted PDMP legislation. In 2021 Missouri, the last State to not use a PMP, adopted legislation to create one. PMPs are constantly being updated to increase speed of data collection, sharing of data across States, and ease of interpretation. This is being done by integrating PDMP reports with other health information technologies such as health information exchanges (HIE), electronic health record (EHR) systems, and/ or pharmacy dispensing software systems. One program that has been implemented in nine states is called the PDMP Electronic Health Records Integration and Interoperability Expansion, also known as PEHRIIE. Another software, marketed by Bamboo Health and integrated with PMPs in 43 states, uses an algorithm to track factors thought to increase risk of diversion, abuse or overdose, and assigns patients a three digit score based on presumed indicators of risk. While some studies have suggested that PDMP-HIT integration and sharing of interstate data brings benefits such as reduced opioid-related inpatient morbidity, others have found no or negative impact on mortality compared to states without PMP data sharing. Patient and media reports suggest need for testing and evaluation of algorithmic software used to score risk, with some patients reporting denial of prescriptions without c explanation or clarity of data. == Goals == Most health care workers support PMPs which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments, as well as law-enforcement agencies. The collaboration supports the legitimate medical use of controlled substances while limiting their abuse and diversion. Pharmacies dispensing controlled substances and prescribers typically must register with their respective state PMPs and (for pharmacies and providers who dispense controlled substances from their offices) report the dispensation to an electronic online database. Some pharmacy software can submit these reports automatically to multiple states. == Usage == === List of programs by state === === Software systems === NarxCare is a prescription drug monitoring program (PDMP) run by Bamboo Health. Bamboo Health was formerly known as Appriss. It is widely used across the United States by pharmacies including Rite Aid as well as those at Walmart and Sam’s Club. The NarxCare software allows doctors to view data about a patient, combining data from the prescription registries of various U.S. states to make the registries interoperable nationally. It also uses machine learning to generate an "Overdose Risk Score" that potentially includes EMS and criminal justice data; these scores have been criticized by researchers and patient advocates for the lack of transparency in the process as well as the potential for disparate treatment of women and minority groups. Advertised as an "analytics tool and care management platform", the NarxCare software allows doctors to view data about a patient including how many pharmacies they have visited and the combinations of medication they are prescribed. It combines data from the prescription registries of various U.S. states, making the registries interoperable nationally. It additionally uses machine learning to generate various three-digit "risk scores" and an overall "Overdose Risk Score", collectively referred to as Narx Scores, in a process that potentially includes EMS and criminal justice data as well as court records. == Controversy == Many doctors and researchers support the idea of PDMPs as a tool in combatting the opioid epidemic. Opioid prescribing, opioid diversion and supply, opioid misuse, and opioid-related morbidity and mortality are common elements in data entered into PDMPs. Prescription Monitoring Programs are purported to offer economic benefits for the states who implement them by decreasing overall health care costs, lost productivity, and investigation times. However, there are many studies that conclude the impact of PDMPs is unclear. While use of PMPs has been accompanied by decrease in opioid prescribing, few analyses consider corresponding use of street opioids, extramedical use, or diversion, which might provide a more holistic method for evaluation of PMP intent and efficacy. Evidence for PDMP impact on fatal overdoses is decidedly mixed, with multiple studies finding increased overdose rates in some states, decreases in others, or no clear impact. Interestingly, an increase in heroin overdoses after PDMP implementation has been commonly reported, presumably as denial of prescription opioids sends patients in search of street drugs. Narx Scores have been criticized by researchers and patient advocates for the lack of transparency in the generation process as well as the potential for disparate treatment of women and minority groups. Writing in Duke Law Journal, Jennifer Oliva stated that "black-box algorithms" are used to generate the scores.

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  • Free Studio

    Free Studio

    Free Studio is a freeware set of multimedia computer programs developed by DVDVideoSoft. The programs are available in one integrated package and also as separate downloads (Free Studio Manager is included in both). == Overview == The Free Studio software bundle consists of about 48 programs, grouped into several sections: YouTube, MP3 & Audio, CD-DVD-BD, DVD & Video, Photo & Images, Mobiles, Apple Devices, and 3D. The largest group is the DVD & Video section containing 14 different applications. Mobiles section is the second largest group with 13 programs. However, the YouTube section, particularly YouTube downloading programs, has gained more popularity among users. The programs have been tested and endorsed by a dozen of software portals and have won awards from these sites. Free Studio is most popular in Germany, Greece, Italy, and the United States. It is also popular in Japan, France, and the United Kingdom. Some of the programs in the package are free and open-source software. == History == DVDVideoSoft project was launched in 2006 by company Digital Wave Ltd., for software development to produce multimedia application software. The founders distributed paid software as an affiliate at the start, later their own products appeared on the site. Free YouTube Download was the first successful program, then DVDVideoSoft created and launched several other 'Free YouTube' applications. Later on upon users' requests DVDVideoSoft started developing other kinds of applications including media converters etc. Today DVDVideoSoft offers up to 49 different programs for video, audio and image processing individually or integrated into the Free Studio package. == Features == DVDVideoSoft YouTube programs can be used to download YouTube videos in their original format and convert them to AVI, DVD, MP4, WMV etc. or different audio formats. YouTube section contains Free Video Call Recorder for Skype button, but the program itself is not included into FS installation (it has to be downloaded and installed separately). The "MP3 & Audio" section consists of the programs which convert audio files between different formats, convert audio files to Flash for web, extract audio from video files, edit audio files (Free Audio Dub), rip and burn CDs. Enclosed in the CD-DVD-BD section are the applications that enable users to burn files and folders to discs, to convert videos to a DVD format and vice versa, to burn CDs, and to copy music from audio CDs into files. The "DVD and Video" section contains several desktop video and DVD converters. Some of the programs can flip, rotate and cut (Free Video Dub) videos. One of the most popular programs from the section is Free Video Dub. Converted videos are now, contrary to previous versions, watermarked if no paid membership is present. Free Studio includes several applications for Apple phones, iPods and other devices. The Mobiles section contains a dozen video converters for various mobile devices such as cell phones, Tablets and Game consoles. They convert videos to play them on (BlackBerry, HTC, LG phones, Sony/Sony Ericsson, Nintendo, Xbox, Motorola phones, etc.) The "Photo & Images" section incorporates the programs for image conversion and resizing, extracting JPEG frames from videos (Free Video To JPEG Converter), recording screen activities, making screenshots (Free Screen Recorder). The 3D section is composed of the programs to make 3D videos and 3D images. There are several algorithms which allow to create different types of 3D images. == Supported formats == === Video formats === Input: .avi; .ivf; .div; .divx; .mpg; .mpeg; .mpe; .mp4; .m4v; .wmv; .asf; .webm; .mkv; .mov; .qt; .ts; .mts; .m2t; .m2ts; .mod; .tod; .vro; .dat; .3gp2; .3gpp; .3gp; .3g2; .dvr-ms; .flv; .f4v; .amv; .rm; .rmm; .rv; .rmvb; .ogv; DVD video Output: .mp4; .wmv; .avi; .mkv; .webm; .flv; .swf; .mov; .3gp; .m2ts; DVD video === Audio formats === Input: .mp3 .wav; .aac; .m4a; .m4b; .wma; .ogg; .flac; .ra; .ram; .amr; .ape; .mka; .tta; .aiff; .au; .mpc; .spx; .ac3; audio cd Output: .mp3; .m4a; .aac; .wav; .wma; .ogg; .flac; .ape; audio CD === Image formats === Input: .jpg, .png, .bmp, .gif, .tga Output: .jpg, .png, .bmp, .gif, .tga, .pdf == Reception == The programs have been tested and endorsed by Chip Online, Tucows, SnapFiles, Brothersoft, and Softonic and have won awards from these sites. Free Studio is most popular in Germany, United States and Italy. It is also popular in Japan, France and the United Kingdom. The most popular applications, according to CNET statistics, include Free YouTube to MP3 Converter, Free Video to MP3 Converter, Free MP4 Video Converter and Free YouTube Download. Other programs with high rank: Free AVI Video Converter, Free Video Editor, Free Audio Converter and Free Studio in a whole. == Criticism == Free Studio (as can be common for freeware packages) is criticized for toolbar and Web search engine installation. Older versions have also included OpenCandy, which is loaded automatically, with no request for user approval. There can be difficulties installing only the programs needed without installing bundled extra programs. In March 2017, DVDVideoSoft announced that it had stopped showing other products' ads during installation and removed all toolbars, search engines, and OpenCandy.

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  • Unique negative dimension

    Unique negative dimension

    Unique negative dimension (UND) is a complexity measure for the model of learning from positive examples. The unique negative dimension of a class C {\displaystyle C} of concepts is the size of the maximum subclass D ⊆ C {\displaystyle D\subseteq C} such that for every concept c ∈ D {\displaystyle c\in D} , we have ∩ ( D ∖ { c } ) ∖ c {\displaystyle \cap (D\setminus \{c\})\setminus c} is nonempty. This concept was originally proposed by M. Gereb-Graus in "Complexity of learning from one-side examples", Technical Report TR-20-89, Harvard University Division of Engineering and Applied Science, 1989.

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  • NETtalk (artificial neural network)

    NETtalk (artificial neural network)

    NETtalk is an artificial neural network that learns to pronounce written English text by supervised learning. It takes English text as input, and produces a matching phonetic transcriptions as output. It is the result of research carried out in the mid-1980s by Terrence Sejnowski and Charles Rosenberg. The intent behind NETtalk was to construct simplified models that might shed light on the complexity of learning human level cognitive tasks, and their implementation as a connectionist model that could also learn to perform a comparable task. The authors trained it by backpropagation. The network was trained on a large amount of English words and their corresponding pronunciations, and is able to generate pronunciations for unseen words with a high level of accuracy. The output of the network was a stream of phonemes, which fed into DECtalk to produce audible speech. It achieved popular success, appearing on the Today show. From the point of view of modeling human cognition, NETtalk does not specifically model the image processing stages and letter recognition of the visual cortex. Rather, it assumes that the letters have been pre-classified and recognized. It is NETtalk's task to learn proper associations between the correct pronunciation with a given sequence of letters based on the context in which the letters appear. A similar architecture was subsequently used for the opposite task, that of converting continuous speech signal to a phoneme sequence. == Training == The training dataset was a 20,008-word subset of the Brown Corpus, with manually annotated phoneme and stress for each letter. The development process was described in a 1993 interview. It took three months -- 250 person-hours -- to create the training dataset, but only a few days to train the network. After it was run successfully on this, the authors tried it on a phonological transcription of an interview with a young Latino boy from a barrio in Los Angeles. This resulted in a network that reproduced his Spanish accent. The original NETtalk was implemented on a Ridge 32, which took 0.275 seconds per learning step (one forward and one backward pass). Training NETtalk became a benchmark to test for the efficiency of backpropagation programs. For example, an implementation on Connection Machine-1 (with 16384 processors) ran at 52x speedup. An implementation on a 10-cell Warp ran at 340x speedup. The following table compiles the benchmark scores as of 1988. Speed is measured in "millions of connections per second" (MCPS). For example, the original NETtalk on Ridge 32 took 0.275 seconds per forward-backward pass, giving 18629 / 10 6 0.275 = 0.068 {\displaystyle {\frac {18629/10^{6}}{0.275}}=0.068} MCPS. Relative times are normalized to the MicroVax. == Architecture == The network had three layers and 18,629 adjustable weights, large by the standards of 1986. There were worries that it would overfit the dataset, but it was trained successfully. The input of the network has 203 units, divided into 7 groups of 29 units each. Each group is a one-hot encoding of one character. There are 29 possible characters: 26 letters, comma, period, and word boundary (whitespace). To produce the pronunciation of a single character, the network takes the character itself, as well as 3 characters before and 3 characters after it. The hidden layer has 80 units. The output has 26 units. 21 units encode for articulatory features (point of articulation, voicing, vowel height, etc.) of phonemes, and 5 units encode for stress and syllable boundaries. Sejnowski studied the learned representation in the network, and found that phonemes that sound similar are clustered together in representation space. The output of the network degrades, but remains understandable, when some hidden neurons are removed.

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