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Logical Machine Corporation

Logical Machine Corporation (LOMAC) was an American computer company active from the mid-1970s to the 1980s and based in the San Francisco Bay Area. It was founded as John Peers and Company by the British entrepreneur John Peers in 1974. LOMAC developed the ADAM, a minicomputer which ran a specialized compiler for the company's natural English programming language. Throughout the late 1970s, the company acquired several technology firms, including Byte, Inc., the owner of the Byte Shop retail chain. Despite its unique approach to computing and earning $5 million in revenue in 1977, LOMAC struggled as the industry began to standardize around the IBM Personal Computer (IBM PC). Following Peers's departure in 1980, the company rebranded as Logical Business Machines, Inc. (LBM, or simply Logical), and attempted to pivot toward IBM PC–compatible hardware. However, financial difficulties led to the company filing for Chapter 11 bankruptcy in 1984. After emerging from bankruptcy in 1985 with new investment, Logical ceased hardware manufacturing to focus exclusively on software development and value-added reselling. == History == John Peers (born 1942) founded Logical Machine Corporation as John Peers and Company in September 1974. The company originally occupied a 4,500-square-foot office in Burlingame, California. The company was Peers' fourth; he had recently sold off Allied Business Systems of London to Trafalgar House in 1974. Peers sought to set up manufacturing in an agricultural zone in Ukiah, California. Following a delay, caused in part by concerned residents, a 30,000-square-foot plant was raised in Burke Hill, three miles south of Ukiah. The Ukiah plant was built to mass manufacture the company's ADAM minicomputer. The ADAM computer ran a specialized compiler for the company's natural English programming language; that is to say, the programming language attempted to closely emulate English syntax. Prototypes of the ADAM were built in May 1974, based on specifications devised in October 1973. Peers had yet to patent the technology as of June 1975. The ADAM's central processing unit was bolted onto an 7-by-6-foot L-shaped desk, on which rested its terminal. Twenty units of the ADAM were installed between April 1975 and February 1976, out of a backlog of orders for 3,500 from 500 clients, manufactured out of the company's Burlingame headquarters. It cost US$40,000. A controversial print advertisement featuring a naked woman seated at an ADAM terminal—as a pastiche of Adam and Eve—was recalled in early 1976 as a result of outcry from the National Organization for Women. The company changed its name to Logical Machine Corporation (LOMAC) in October 1976 and moved its headquarters to a 26,000-square-foot building in Sunnyvale, California, in anticipation of a ramping up of orders for the ADAM. The company originally occupied half of the building; they later purchased the other half from the tenant in July 1977 to double its manufacturing output. For fiscal year 1977, the company earned $5 million in revenue. In December 1977, LOMAC acquired Byte, Inc.—the proprietor of The Byte Shop, the first computer retail chain—from Paul Terrell and Boyd Wilson for an unspecified amount. The Byte Shop had 65 locations in the San Francisco Bay Area in 1978; it catered mainly to hobbyists with low cost microcomputer kits, in contrast to the high cost of LOMAC's ADAM. By July 1978, however, LOMAC were able to reduce the price of the ADAM down to $15,000. The company by that point had shipped their 50th ADAM and expanded to 14 countries. Also in 1978, LOMAC acquired Mass Memory—a high-tech optical storage company based in Phoenix, Arizona, whose products had storage capacities on the order gigabytes and terabytes—and Centigram, makers of the Mike—a computer with speech recognition. Later that year, the company introduced Tina, a low-cost version of the ADAM. LOMAC suffered losses that year and appointed Jerry Brandt to the board of directions, naming him chief operating officer, in August 1978. Brandt had Logical absorb Mass Memory and Centigram into the parent operations, shutting down their respective plants in the process, converted 10 Byte Shops to franchises and opened 25 more franchised Byte locations, and stopped direct sales of LOMAC's business computer products. By the beginning of 1979, LOMAC was profitable once more, and Brandt was let go from LOMAC. Peers left LOMAC in 1980, following a slump in the company's sales. He became an executive director of the United States Robotics Society, a consortium for industrial automation companies, that year. Following Peers' departure, LOMAC changed its name to Logical Business Machines, adopting the name of its European subsidiary. In 1983, the company announced a 16-bit clone of the IBM PC, called the Logical L-XT, which featured a 10-MB hard drive, 320-KB floppy drive and 192 KB of RAM, and a real-time clock, and came shipped with various software (including MS-DOS, a word processor, and a spreadsheet application) and an amber CRT monitor. The following year, the company introduced L-NET, a local area network system based on the L-XT that could link up to 64 computers. L-NET came shipped with a natural programming language, Diplomat—a descendant of the programming language used on the ADAM. In June 1983, Logical sued Coleco Industries over trademark infringement with the latter's to-be-released Adam microcomputer. Logical cited confusion from their existing ADAM customer base caused by the announcement of the Coleco Adam as the basis for the suit. Coleco challenged Logical in the press, writing that Logical's rights to the Adam trademark for use in computers had lapsed earlier in the year. The two settled out of court, with Coleco agreeing to license the Adam name from Logical in exchange for unlimited rights to the Adam trademark. Logical halted development of the L-XT when they filed for Chapter 11 bankruptcy in July 1984. The company had been $4 million in debt. They emerged from bankruptcy in September 1985, after being infused with $2 million from Carat Ltd. The latter immediately received a little less than 50 percent ownership in Logical—this stake set to grow to over 50 percent over the next six months. As part of the terms of exiting bankruptcy, Logical stopped manufacturing hardware and strictly became a software development company and value-added reseller of computer systems.
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Geopolitical ontology

The FAO geopolitical ontology is an ontology developed by the Food and Agriculture Organization of the United Nations (FAO) to describe, manage and exchange data related to geopolitical entities such as countries, territories, regions and other similar areas. == Definitions and examples == An ontology is a kind of dictionary that describes information in a certain domain using concepts and relationships. It is often implemented using OWL (Web Ontology Language), an XML-based standard language that can be interpreted by computers. A Concept is defined as abstract knowledge. For example, in the geopolitical ontology a non-self-governing territory and a geographical group are concepts. Concepts are explicitly implemented in the ontology with individuals and classes: An individual is defined as an object perceived from the real world. In the geopolitical domain Ethiopia and the least developed countries group are individuals. A class is defined as a set of individuals sharing common properties. In the geopolitical domain, Ethiopia, Republic of Korea and Italy are individuals of the class self-governing territory; and least developed countries is an individual of the class special group. Relationships between concepts are explicitly implemented by: Object properties between individuals of two classes. For example, has member and is in group properties, as shown in Figure 1. Datatype properties between individuals and literals or XML datatypes. For example, the individual Afghanistan has the datatype property CodeISO3 with the value "AFG". Restrictions in classes and/or properties. For example, the property official English name of the class self-governing territory has been restricted to have only one value, this means that a self-governing territory (or country) can only have one internationally recognized official English name. The advantage of describing information in an ontology is that it enables to acquire domain knowledge by defining hierarchical structures of classes, adding individuals, setting object properties and datatype properties, and assigning restrictions. == FAO ontology == The geopolitical ontology provides names in seven languages (Arabic, Chinese, French, English, Spanish, Russian and Italian) and identifiers in various international coding systems (ISO2, ISO3, AGROVOC, FAOSTAT, FAOTERM, GAUL, UN, UNDP and DBPediaID codes) for territories and groups. Moreover, the FAO geopolitical ontology tracks historical changes from 1985 up until today; provides geolocation (geographical coordinates); implements relationships among countries and countries, or countries and groups, including properties such as has border with, is predecessor of, is successor of, is administered by, has members, and is in group; and disseminates country statistics including country area, land area, agricultural area, GDP or population. The FAO geopolitical ontology provides a structured description of data sources. This includes: source name, source identifier, source creator and source's update date. Concepts are described using the Dublin Core vocabulary In summary, the main objectives of the FAO geopolitical ontology are: To provide the most updated geopolitical information (names, codes, relationships, statistics) To track historical changes in geopolitical information To improve information management and facilitate standardized data sharing of geopolitical information To demonstrate the benefits of the geopolitical ontology to improve interoperability of corporate information systems It is possible to download the FAO geopolitical ontology in OWL and RDF formats. Documentation is available in the FAO Country Profiles Geopolitical information web page. == Features of the FAO ontology == The geopolitical ontology contains : Area types: Territories: self-governing, non-self-governing, disputed, other. Groups: organizations, geographic, economic and special groups. Names (official, short and names for lists) in Arabic, Chinese, English, French, Spanish, Russian and Italian. International codes: UN code – M49, ISO 3166 Alpha-2 and Alpha-3, UNDP code, GAUL code, FAOSTAT, AGROVOC FAOTERM and DBPediaID. Coordinates: maximum latitude, minimum latitude, maximum longitude, minimum longitude. Basic country statistics: country area, land area, agricultural area, GDP, population. Currency names and codes. Adjectives of nationality. Relations: Groups membership. Neighbours (land border), administration of non-self-governing. Historic changes: predecessor, successor, valid since, valid until. == Implementation into OWL == The FAO geopolitical ontology is implemented in OWL. It consists of classes, properties, individuals and restrictions. Table 1 shows all classes, gives a brief description and lists some individuals that belong to each class. Note that the current version of the geopolitical ontology does not provide individuals of the class "disputed" territories. Table 2 and Table 3 illustrate datatype properties and object properties. == Geopolitical ontology in Linked Open Data == The FAO Geopolitical ontology is embracing the W3C Linked Open Data (LOD) initiative and released its RDF version of the geopolitical ontology in March 2011. The term 'Linked Open Data' refers to a set of best practices for publishing and connecting structured data on the Web. The key technologies that support Linked Data are URIs, HTTP and RDF. The RDF version of the geopolitical ontology is compliant with all Linked data principles to be included in the Linked Open Data cloud, as explained in the following. == Resolvable http:// URIs == Every resource in the OWL format of the FAO Geopolitical Ontology has a unique URI. Dereferenciation was implemented to allow for three different URIs to be assigned to each resource as follows: URI identifying the non-information resource Information resource with an RDF/XML representation Information resource with an HTML representation In addition the current URIs used for OWL format needed to be kept to allow for backwards compatibility for other systems that are using them. Therefore, the new URIs for the FAO Geopolitical Ontology in LOD were carefully created, using “Cool URIs for Semantic Web” and considering other good practices for URIs, such as DBpedia URIs. == New URIs == The URIs of the geopolitical ontology need to be permanent, consequently all transient information, such as year, version, or format was avoided in the definition of the URIs. The new URIs can be accessed For example, for the resource “Italy” the URIs are the following: http://www.fao.org/countryprofiles/geoinfo/geopolitical/resource/Italy identifies the non-information resource. http://www.fao.org/countryprofiles/geoinfo/geopolitical/data/Italy identifies the resource with an RDF/XML representation. http://www.fao.org/countryprofiles/geoinfo/geopolitical/page/Italy identifies the information resource with an HTML representation. In addition, “owl:sameAs” is used to map the new URIs to the OWL representation. == Dereferencing URIs == When a non-information resource is looked up without any specific representation format, then the server needs to redirect the request to information resource with an HTML representation. For example, to retrieve the resource “Italy”, which is a non-information resource, the server redirects to the HTML page of “Italy”. == At least 1000 triples in the datasets == The total number of triple statements in FAO Geopolitical Ontology is 22,495. At least 50 links to a dataset already in the current LOD Cloud: FAO Geopolitical Ontology has 195 links to DBpedia, which is already part of the LOD Cloud. == Access to the entire dataset == FAO Geopolitical Ontology provides the entire dataset as a RDF dump. The RDF version of the FAO Geopolitical Ontology has been already registered in CKAN and it was requested to add it into the LOD Cloud. == Example of use == The FAO Country Profiles is an information retrieval tool which groups the FAO's vast archive of information on its global activities in agriculture and rural development in one single area and catalogues it exclusively by country. The FAO Country Profiles system provides access to country-based heterogeneous data sources. By using the geopolitical ontology in the system, the following benefits are expected: Enhanced system functionality for content aggregation and synchronization from the multiple source repositories. Improved information access and browsing through comparison of data in neighbor countries and groups. Figure 3 shows a page in the FAO Country Profiles where the geopolitical ontology is described.
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MIT Computer Science and Artificial Intelligence Laboratory

Computer Science and Artificial Intelligence Laboratory (CSAIL) is a research institute at the Massachusetts Institute of Technology (MIT) formed by the 2003 merger of the Laboratory for Computer Science (LCS) and the Artificial Intelligence Laboratory (AI Lab). Housed within the Ray and Maria Stata Center, CSAIL is the largest on-campus laboratory as measured by research scope and membership. It is part of the Schwarzman College of Computing but is also overseen by the MIT Vice President of Research. == Research activities == CSAIL's research activities are organized around a number of semi-autonomous research groups, each of which is headed by one or more professors or research scientists. These groups are divided up into seven general areas of research: Artificial intelligence Computational biology Graphics and vision Language and learning Theory of computation Robotics Systems (includes computer architecture, databases, distributed systems, networks and networked systems, operating systems, programming methodology, and software engineering, among others) == History == Computing Research at MIT began with Vannevar Bush's research into a differential analyzer and Claude Shannon's electronic Boolean algebra in the 1930s, the wartime MIT Radiation Laboratory, the post-war Project Whirlwind and the Research Laboratory of Electronics (RLE), and MIT Lincoln Laboratory's SAGE in the early 1950s. At MIT, research in the field of artificial intelligence began in the late 1950s. === Project MAC === On July 1, 1963, Project MAC (the Project on Mathematics and Computation, later backronymed to Multiple Access Computer, Machine Aided Cognitions, or Man and Computer) was launched with a $2 million grant from the Defense Advanced Research Projects Agency (DARPA). Project MAC's original director was Robert Fano of MIT's Research Laboratory of Electronics (RLE). Fano decided to call MAC a "project" rather than a "laboratory" for reasons of internal MIT politics – if MAC had been called a laboratory, then it would have been more difficult to raid other MIT departments for research staff. The program manager responsible for the DARPA grant was J. C. R. Licklider, who had previously been at MIT conducting research in RLE, and would later succeed Fano as director of Project MAC. Project MAC would become famous for groundbreaking research in operating systems, artificial intelligence, and the theory of computation. Its contemporaries included Project Genie at Berkeley, the Stanford Artificial Intelligence Laboratory, and (somewhat later) University of Southern California's (USC's) Information Sciences Institute. An "AI Group" including Marvin Minsky (the director), John McCarthy (inventor of Lisp), and a talented community of computer programmers were incorporated into Project MAC. They were interested principally in the problems of vision, mechanical motion and manipulation, and language, which they view as the keys to more intelligent machines. In the 1960s and 1970s the AI Group developed a time-sharing operating system called Incompatible Timesharing System (ITS) which ran on PDP-6 and later PDP-10 computers. The early Project MAC community included Fano, Minsky, Licklider, Fernando J. Corbató, and a community of computer programmers and enthusiasts among others who drew their inspiration from former colleague John McCarthy. These founders envisioned the creation of a computer utility whose computational power would be as reliable as an electric utility. To this end, Corbató brought the first computer time-sharing system, Compatible Time-Sharing System (CTSS), with him from the MIT Computation Center, using the DARPA funding to purchase an IBM 7094 for research use. One of the early focuses of Project MAC would be the development of a successor to CTSS, Multics, which was to be the first high availability computer system, developed as a part of an industry consortium including General Electric and Bell Laboratories. In 1966, Scientific American featured Project MAC in the September thematic issue devoted to computer science, that was later published in book form. At the time, the system was described as having approximately 100 TTY terminals, mostly on campus but with a few in private homes. Only 30 users could be logged in at the same time. The project enlisted students in various classes to use the terminals simultaneously in problem solving, simulations, and multi-terminal communications as tests for the multi-access computing software being developed. === AI Lab and LCS === In the late 1960s, Minsky's artificial intelligence group was seeking more space, and was unable to get satisfaction from project director Licklider. Minsky found that although Project MAC as a single entity could not get the additional space he wanted, he could split off to form his own laboratory and then be entitled to more office space. As a result, the MIT AI Lab was formed in 1970, and many of Minsky's AI colleagues left Project MAC to join him in the new laboratory, while most of the remaining members went on to form the Laboratory for Computer Science. Talented programmers such as Richard Stallman, who used TECO to develop EMACS, flourished in the AI Lab during this time. Those researchers who did not join the smaller AI Lab formed the Laboratory for Computer Science and continued their research into operating systems, programming languages, distributed systems, and the theory of computation. Two professors, Hal Abelson and Gerald Jay Sussman, chose to remain neutral—their group was referred to variously as Switzerland and Project MAC for the next 30 years. Among much else, the AI Lab led to the invention of Lisp machines and their attempted commercialization by two companies in the 1980s: Symbolics and Lisp Machines Inc. === CSAIL === On the fortieth anniversary of Project MAC's establishment, July 1, 2003, LCS was merged with the AI Lab to form the MIT Computer Science and Artificial Intelligence Laboratory, or CSAIL. This merger created the largest laboratory (over 600 personnel) on the MIT campus. In 2018, CSAIL launched a five-year collaboration program with IFlytek, a company sanctioned the following year for allegedly using its technology for surveillance and human rights abuses in Xinjiang. In October 2019, MIT announced that it would review its partnerships with sanctioned firms such as iFlyTek and SenseTime. In April 2020, the agreement with iFlyTek was terminated. CSAIL moved from the School of Engineering to the newly formed Schwarzman College of Computing by February 2020. == Offices == From 1963 to 2004, Project MAC, LCS, the AI Lab, and CSAIL had their offices at 545 Technology Square, taking over more and more floors of the building over the years. In 2004, CSAIL moved to the new Ray and Maria Stata Center, which was built specifically to house it and other departments. == Outreach activities == The IMARA (from Swahili word for "power") group sponsors a variety of outreach programs that bridge the global digital divide. Its aim is to find and implement long-term, sustainable solutions which will increase the availability of educational technology and resources to domestic and international communities. These projects are run under the aegis of CSAIL and staffed by MIT volunteers who give training, install and donate computer setups in greater Boston, Massachusetts, Kenya, Native American Indian tribal reservations in the American Southwest such as the Navajo Nation, the Middle East, and Fiji Islands. The CommuniTech project strives to empower under-served communities through sustainable technology and education and does this through the MIT Used Computer Factory (UCF), providing refurbished computers to under-served families, and through the Families Accessing Computer Technology (FACT) classes, it trains those families to become familiar and comfortable with computer technology. == Notable researchers == (Including members and alumni of CSAIL's predecessor laboratories) MacArthur Fellows Tim Berners-Lee, Erik Demaine, Dina Katabi, Daniela L. Rus, Regina Barzilay, Peter Shor, Richard Stallman, and Joshua Tenenbaum Turing Award recipients Leonard M. Adleman, Fernando J. Corbató, Shafi Goldwasser, Butler W. Lampson, John McCarthy, Silvio Micali, Marvin Minsky, Ronald L. Rivest, Adi Shamir, Barbara Liskov, and Michael Stonebraker IJCAI Computers and Thought Award recipients Terry Winograd, Patrick Winston, David Marr, Gerald Jay Sussman, Rodney Brooks Rolf Nevanlinna Prize recipients Madhu Sudan, Peter Shor, Constantinos Daskalakis Gödel Prize recipients Shafi Goldwasser (two-time recipient), Silvio Micali, Maurice Herlihy, Charles Rackoff, Johan Håstad, Peter Shor, and Madhu Sudan Grace Murray Hopper Award recipients Robert Metcalfe, Shafi Goldwasser, Guy L. Steele, Jr., Richard Stallman, and W. Daniel Hillis Textbook authors Harold Abelson and Gerald Jay Sussman, Richard Stallman, Thomas H. Cormen, Charles E. Leiserson, Patrick Winston, Ronald L.
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TRAIGA

TRAIGA, or the Texas Responsible Artificial Intelligence Governance Act, is a state law regulating the development and deployment of artificial intelligence (AI) systems in Texas. Sponsored by Representative Giovanni Capriglione, the Act establishes a framework governing certain uses of AI, outlines prohibited uses, and creates obligations on state government entities, among other provisions. TRAIGA was signed into law in 2025 and took effect on January 1, 2026. The law applies to AI developers and deployers that conduct business in Texas or whose systems are used by Texas residents. It prohibits the intentional development or deployment of AI systems to incite harm, violate constitutional rights, engage in unlawful discrimination, and produce child sexual abuse material or unlawful deepfakes. TRAIGA also establishes the Texas Artificial Intelligence Council and creates a regulatory sandbox program. The Texas Attorney General is charged with enforcement. It has received attention as one of the first comprehensive AI-related laws enacted by a U.S. state. Legal analysts have compared it to the European Union (EU) Artificial Intelligence Act and the Colorado AI Act, noting its intent-based discrimination standard and narrower scope relative to those frameworks. == Background == In June 2023, Texas Governor Greg Abbott signed House Bill 2060, which created an Artificial Intelligence Advisory Council within the Texas Department of Information Resources. The Council was tasked with monitoring the use of AI systems across state government. Its membership included representatives from law enforcement, academia, and the legal profession. After submitting a report to state policymakers, the Council was disbanded in December 2024. Separately, the Texas House Select Committee on Artificial Intelligence and Emerging Technologies was created in 2023 to examine the political and social implications of artificial intelligence. Among its recommendations was the creation of a regulatory sandbox to allow for controlled testing of AI systems. This recommendation informed the regulatory sandbox provision included in TRAIGA. == History == In December 2024, Representative Capriglione introduced House Bill 1709, the Texas Responsible Artificial Intelligence Governance Act. The bill sought to create a statewide framework for artificial intelligence, including transparency requirements for companies deploying AI systems, restrictions on certain uses of AI, and the creation of a regulatory sandbox. Modeled in part on the EU Artificial Intelligence Act and the Colorado AI Act, House Bill 1709 focused on "high-risk" AI systems and included provisions addressing private sector liability. House Bill 1709 did not advance during the legislative session. Industry stakeholders raised concerns that several provisions were overly burdensome. The bill informed the development of a revised proposal, House Bill 149, also titled the Texas Responsible Artificial Intelligence Governance Act. The revised version removed requirements for private companies to notify consumers when they interact with AI systems and to conduct impact assessments, among other provisions. In April 2025, an amended version of House Bill 149 passed the Texas House of Representatives and was referred to the Senate Committee on Business and Commerce. The bill later received approval from both chambers, where the House voted on amendments adopted by the Senate. On May 31, 2025, the state legislature passed House Bill 149, one of several AI-related bills considered during the legislative session. Governor Abbott signed TRAIGA into law on June 22, 2025. During the legislative process, a proposed federal moratorium on state-level AI regulation initially raised questions about the enforceability of state AI laws, including TRAIGA. At the time of signing, Governor Abbott stated that Texas would ensure compliance with applicable federal requirements. In July 2025, the United States Senate voted to remove the proposed moratorium from federal legislation. The Act took effect on January 1, 2026. == Provisions == === Definitions and scope === TRAIGA applies to AI developers and deployers that advertise or conduct business in Texas, develop products used by Texas residents, or develop or deploy AI systems within the state. The Act also applies to Texas state and local government entities. The Act defines a developer as a person who develops an AI system and a deployer as one who deploys an AI system in Texas. Consumers are defined as Texas residents. The Act defines an artificial intelligence system as a machine-based system that "infers from the inputs the system receives how to generate outputs, including content, decisions, predictions, or recommendations, that can influence physical or virtual environments." === Government use === The Act requires government agencies to provide consumers with plain language notices before interacting with AI systems. It also prohibits government agencies from using artificial intelligence systems to assign social scores to consumers. It also restricts the use of AI systems to identify individuals using biometric data without the individual’s consent. === Prohibitions === The Act prohibits the development or deployment of artificial intelligence systems intended to cause harm, self-harm, or criminal activity. It also prohibits the development or deployment of AI systems designed to violate constitutional rights or unlawfully discriminate based on protected classes. In addition, the Act prohibits the development or deployment of AI systems that are intended to produce or distribute child sexual abuse material or unlawful deepfakes. === Enforcement === Enforcement authority under the Act rests with the Texas Attorney General. The Act does not create a private right of action. The Act requires the Texas Attorney General to create an online complaint system where consumers may submit allegations of potential violations. The Attorney General can investigate complaints received through this system and may request information relevant to the operation of an AI system, including information about training data. Before initiating an enforcement action, the Attorney General must provide a written notice to the alleged violator, who is then provided with a 60-day period to cure the alleged violation. === Penalties === If a violation is not cured, the Act authorizes civil penalties. Penalties range from $10,000 to $12,000 per curable violation and from $80,000 to $200,000 per non-curable violation. The Act also authorizes additional penalties of $2,000 to $40,000 for each day the violation continues. If the Attorney General determines that a person certified or licensed by a state agency has violated the Act and recommends enforcement, the relevant agency may impose additional administrative sanctions, including license suspension or further monetary penalties. === Safe harbor === The Act provides an affirmative defense for AI developers and deployers who identify potential violations through internal testing or auditing or who demonstrate compliance with National Institute of Standards and Technology (NIST)'s Artificial Intelligence Risk Management Framework or a comparable risk management framework. The Act also affords protection to developers and deployers when a third party uses their AI systems in a way that violates the Act. === Texas Artificial Intelligence Council === The Act creates the Texas Artificial Intelligence Council to assist the state legislatures in evaluating artificial intelligence policy and oversight. The Council is charged with developing recommendations for state agencies regarding the use of AI systems and with overseeing the regulatory sandbox. TRAIGA gives the Council the ability to organize AI-related training for state entities and issue reports concerning artificial intelligence. The Council does not have binding rulemaking authority. The Council consists of seven members appointed by the governor, the lieutenant governor, and the speaker of the Texas House of Representatives. === Regulatory sandbox === The Act directs the Texas Department of Information Resources to create a regulatory sandbox program that allows participants to test AI systems under state supervision in a modified regulatory setting. To join the program, companies must submit applications that describe their AI systems and intended use. Approved participants may operate within the sandbox for up to 36 months. During that period, the Attorney General is restricted from initiating enforcement actions for certain categories of violations. == Reception == === Support === During legislative testimony, the Texas Public Policy Foundation stated that TRAIGA would benefit Texas businesses by reducing legal ambiguity and creating clearer compliance standards. Representatives of business groups also expressed support, stating that the Act would not impose overly burdensome regulations. The consum
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Customer support

Customer support is a range of services to assist customers in making cost effective and correct use of a product. It includes assistance in planning, installation, training, troubleshooting, maintenance, upgrading, and disposal of a product. Regarding technology products such as mobile phones, televisions, computers, software products or other electronic or mechanical goods, it is termed technical support. It aims to ensure users can effectively operate the product and resolve any issues that may arise throughout its lifecycle. Support is delivered through various channels, including telephone, email, live chat, self-service knowledge bases, and social media. Research indicates that most customers attempt to resolve issues through self-service before contacting a representative. For products sold across multiple regions, support may be provided in several languages, as consumers tend to prefer assistance in their native language. Requirements for customer contact centres are defined in international standards such as ISO 18295.
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Artificial intelligence systems integration

The core idea of artificial intelligence systems integration is making individual software components, such as speech synthesizers, interoperable with other components, such as common sense knowledgebases, in order to create larger, broader and more capable A.I. systems. The main methods that have been proposed for integration are message routing, or communication protocols that the software components use to communicate with each other, often through a middleware blackboard system. Most artificial intelligence systems involve some sort of integrated technologies, for example, the integration of speech synthesis technologies with that of speech recognition. However, in recent years, there has been an increasing discussion on the importance of systems integration as a field in its own right. Proponents of this approach are researchers such as Marvin Minsky, Aaron Sloman, Deb Roy, Kristinn R. Thórisson and Michael A. Arbib. A reason for the recent attention A.I. integration is attracting is that there have already been created a number of (relatively) simple A.I. systems for specific problem domains (such as computer vision, speech synthesis, etc.), and that integrating what's already available is a more logical approach to broader A.I. than building monolithic systems from scratch. == Integration focus == The focus on systems' integration, especially with regard to modular approaches, derive from the fact that most intelligences of significant scales are composed of a multitude of processes and/or utilize multi-modal input and output. For example, a humanoid-type of intelligence would preferably have to be able to talk using speech synthesis, hear using speech recognition, understand using a logical (or some other undefined) mechanism, and so forth. In order to produce artificially intelligent software of broader intelligence, integration of these modalities is necessary. == Challenges and solutions == Collaboration is an integral part of software development as evidenced by the size of software companies and the size of their software departments. Among the tools to ease software collaboration are various procedures and standards that developers can follow to ensure quality, reliability and that their software is compatible with software created by others (such as W3C standards for webpage development). However, collaboration in fields of A.I. has been lacking, for the most part not seen outside the respected schools, departments or research institutes (and sometimes not within them either). This presents practitioners of A.I. systems integration with a substantial problem and often causes A.I. researchers to have to 're-invent the wheel' each time they want a specific functionality to work with their software. Even more damaging is the "not invented here" syndrome, which manifests itself in a strong reluctance of A.I. researchers to build on the work of others. The outcome of this in A.I. is a large set of "solution islands": A.I. research has produced numerous isolated software components and mechanisms that deal with various parts of intelligence separately. To take some examples: Speech synthesis FreeTTS from CMU Speech recognition Sphinx from CMU Logical reasoning OpenCyc from Cycorp Open Mind Common Sense Net from MIT With the increased popularity of the free software movement, a lot of the software being created, including A.I. systems, is available for public exploit. The next natural step is to merge these individual software components into coherent, intelligent systems of a broader nature. As a multitude of components (that often serve the same purpose) have already been created by the community, the most accessible way of integration is giving each of these components an easy way to communicate with each other. By doing so, each component by itself becomes a module, which can then be tried in various settings and configurations of larger architectures. Some challenging and limitations of using A.I. software is the uncontrolled fatal errors. For example, serious and fatal errors have been discovered in very precise fields such as human oncology, as in an article published in the journal Oral Oncology Reports entitled "When AI goes wrong: Fatal errors in oncological research reviewing assistance". The article pointed out a grave error in artificial intelligence based on GBT in the field of biophysics. Many online communities for A.I. developers exist where tutorials, examples, and forums aim at helping both beginners and experts build intelligent systems. However, few communities have succeeded in making a certain standard, or a code of conduct popular to allow the large collection of miscellaneous systems to be integrated with ease. == Methodologies == === Constructionist design methodology === The constructionist design methodology (CDM, or 'Constructionist A.I.') is a formal methodology proposed in 2004, for use in the development of cognitive robotics, communicative humanoids and broad AI systems. The creation of such systems requires the integration of a large number of functionalities that must be carefully coordinated to achieve coherent system behavior. CDM is based on iterative design steps that lead to the creation of a network of named interacting modules, communicating via explicitly typed streams and discrete messages. The OpenAIR message protocol (see below) was inspired by the CDM and has frequently been used to aid in the development of intelligent systems using CDM. == Examples == ASIMO, Honda's humanoid robot, and QRIO, Sony's version of a humanoid robot. Cog, M.I.T. humanoid robot project under the direction of Rodney Brooks. AIBO, Sony's robot dog, integrates vision, hearing and motorskills. TOPIO, TOSY's humanoid robot can play ping-pong with human
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Thomas Bolander

Thomas Bolander is a Danish professor at DTU Compute, Technical University of Denmark, where he studies logic and artificial intelligence. Most of his studies focus on the social aspect of artificial intelligence, and how we can make future AI able to navigate in social interactions. Thomas Bolander also sits in different commissions, expert panels and boards, among these he is a member of the Siri Commission, the TeckDK Commission, a member of the editorial board of the journal Studia Logica and co-organizer of Science and Cocktails. Bolander is known for his dissemination of science. In 2019 he was awarded the H. C. Ørsted Medal. Which he was the first to achieve after a break of three years.
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Dataism

Dataism is a term that has been used to describe the mindset or philosophy created by the emerging significance of big data. It was first used by David Brooks in The New York Times in 2013. The term has been expanded to describe what historian Yuval Noah Harari, in his book Homo Deus: A Brief History of Tomorrow from 2015, calls an emerging ideology or even a new form of religion, in which "information flow" is the "supreme value". In art, the term was used by Albert-Laszlo Barabasi to refer to an artist movement that uses data as its primary source of inspiration. == History == "If you asked me to describe the rising philosophy of the day, I'd say it is Data-ism", wrote David Brooks in The New York Times in February 2013. Brooks argued that in a world of increasing complexity, relying on data could reduce cognitive biases and "illuminate patterns of behavior we haven't yet noticed". In 2015, Steve Lohr's book Data-ism looked at how Big Data is transforming society, using the term to describe the Big Data revolution. In his 2016 book Homo Deus: A Brief History of Tomorrow, Yuval Noah Harari argues that all competing political or social structures can be seen as data processing systems: "Dataism declares that the universe consists of data flows, and the value of any phenomenon or entity is determined by its contribution to data processing" and "we may interpret the entire human species as a single data processing system, with individual humans serving as its chips." According to Harari, a Dataist should want to "maximise dataflow by connecting to more and more media". Harari predicts that the logical conclusion of this process is that, eventually, humans will give algorithms the authority to make the most important decisions in their lives, such as whom to marry and which career to pursue. Harari argues that Aaron Swartz could be called the "first martyr" of Dataism. In 2022, Albert-László Barabási coined the term "Dataism" to define an artistic movement that positions data as the central means of understanding nature, society, technology, and human essence. This movement underscores the necessity for art to integrate with data to stay relevant in contemporary society. Dataism responds to the intricacy and interconnectedness of modern social, economic, and technological realms, which exceed individual understanding. Advocating for the use of methodologies from various fields like science, business, and politics in art, Dataism sees this fusion as essential for art to retain its significance and influence. == Criticism == Commenting on Harari's characterisation of Dataism, security analyst Daniel Miessler believes that Dataism does not present the challenge to the ideology of liberal humanism that Harari claims, because humans will simultaneously be able to believe in their own importance and that of data. Harari himself raises some criticisms, such as the problem of consciousness, which Dataism is unlikely to illuminate. Humans may also find out that organisms are not algorithms, he suggests. Dataism implies that all data is public, even personal data, to make the system work as a whole, which is a factor that's already showing resistance today. Other analysts, such as Terry Ortleib, have looked at the extent to which Dataism poses a dystopian threat to humanity. The Facebook–Cambridge Analytica data scandal showed how political leaders manipulated Facebook's users' data to build specific psychological profiles that went on to manipulate the network. A team of data analysts reproduced the AI technology developed by Cambridge Analytica around Facebook's data and was able to define the following rules: 10 likes enables a machine to know a person like a coworker, 70 likes like a friend would, 150 likes like a parent would, 300 likes like a lover would, and beyond it may be possible to know a people better than they know themselves.
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Symbaloo

Symbaloo is a cloud-based site that allows users to organize and categorize web links in the form of buttons. Symbaloo works from a web browser and can be configured as a homepage, allowing users to create a personalized virtual desktop accessible from any device with an Internet connection. Symbaloo users, which must be previously registered, have a page with a grid of buttons that can be configured to link to a specific page. The site allows users to assign different colors to the buttons for easy visual classification. Symbaloo allows a single user to create different pages or screens with buttons. These screens called webmix are useful to separate topics and links can be shared with other users, making them public and sending the link via email. As of 2015 Symbaloo has 6 million users worldwide and mainly used as an online education resource. Symbaloo's slogan is "Start Simple".
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LightGBM

LightGBM, short for Light Gradient-Boosting Machine, is a free and open-source distributed gradient-boosting framework for machine learning, originally developed by Microsoft. It is based on decision tree algorithms and used for ranking, classification and other machine learning tasks. The development focus is on performance and scalability. == Overview == The LightGBM framework supports different algorithms including GBT, GBDT, GBRT, GBM, MART and RF. LightGBM has many of XGBoost's advantages, including sparse optimization, parallel training, multiple loss functions, regularization, bagging, and early stopping. A major difference between the two lies in the construction of trees. LightGBM does not grow a tree level-wise — row by row — as most other implementations do. Instead it grows trees leaf-wise. It will choose the leaf with max delta loss to grow. Besides, LightGBM does not use the widely used sorted-based decision tree learning algorithm, which searches the best split point on sorted feature values, as XGBoost or other implementations do. Instead, LightGBM implements a highly optimized histogram-based decision tree learning algorithm, which yields great advantages on both efficiency and memory consumption. The LightGBM algorithm utilizes two novel techniques called Gradient-Based One-Side Sampling (GOSS) and Exclusive Feature Bundling (EFB) which allow the algorithm to run faster while maintaining a high level of accuracy. LightGBM works on Linux, Windows, and macOS and supports C++, Python, R, and C#. The source code is licensed under MIT License and available on GitHub. == Gradient-based one-side sampling == When using gradient descent, one thinks about the space of possible configurations of the model as a valley, in which the lowest part of the valley is the model which most closely fits the data. In this metaphor, one walks in different directions to learn how much lower the valley becomes. Typically, in gradient descent, one uses the whole set of data to calculate the valley's slopes. However, this commonly used method assumes that every data point is equally informative. By contrast, Gradient-Based One-Side Sampling (GOSS), a method first developed for gradient-boosted decision trees, does not rely on the assumption that all data are equally informative. Instead, it treats data points with smaller gradients (shallower slopes) as less informative by randomly dropping them. This is intended to filter out data which may have been influenced by noise, allowing the model to more accurately model the underlying relationships in the data. == Exclusive feature bundling == Exclusive feature bundling (EFB) is a near-lossless method to reduce the number of effective features. In a sparse feature space many features are nearly exclusive, implying they rarely take nonzero values simultaneously. One-hot encoded features are a perfect example of exclusive features. EFB bundles these features, reducing dimensionality to improve efficiency while maintaining a high level of accuracy. The bundle of exclusive features into a single feature is called an exclusive feature bundle.
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ELVIS Act

The ELVIS Act or Ensuring Likeness Voice and Image Security Act, signed into law by Tennessee Governor Bill Lee on March 21, 2024, marked a significant milestone in the area of regulation of artificial intelligence and public sector policies for artists in the era of artificial intelligence (AI) and AI alignment. It was noted as the first enacted legislation in the United States specifically designed to protect musicians from the unauthorized use of their voices through artificial intelligence technologies and against audio deepfakes and voice cloning. This legislation distinguishes itself by adding penalties for copying a performer's voice. == Origin and advocacy == The inception of the ELVIS Act has been attributed to Gebre Waddell, founder of Sound Credit, who initially conceptualized a framework in 2023 that later evolved into the legislation. Representative Justin J. Pearson acknowledged Waddell's pivotal role during the March 4 House Floor Session on the bill. Leading Tennessee musicians supported the ELVIS Act. Tennessee Governor Bill Lee endorsed it as a Governor's Bill, and it was introduced in the Tennessee Legislature as House Bill 2091 by William Lamberth (R-44) and Senate Bill 2096 by Jack Johnson (R-27). The ELVIS Act is an amendment to a 1984 law that was the result of the Elvis Presley estate litigation for controlling how his likeness could be used after death. == Lobbying from the recording industry == The legislative journey of the ELVIS Act included a broad coalition of music industry stakeholders, including: These organizations, led by the Recording Academy and the RIAA, played roles in drafting the legislation, advocating for passage, and rallying support among the industry and legislators. The act gained momentum through discussions that bridged industry concerns with legislative action. This collaborative process led to a proposal that specifically targets the use of AI to create unauthorized reproductions of artists' voices and images. == Opposition == The ELVIS Act saw industry opposition from the Motion Picture Association, including testimony in the House Banking & Consumer Affairs Subcommittee, including remarks that the law risks "interference with our members’ ability to portray real people and events." TechNet, representing companies such as OpenAI, Google and Amazon, expressed their opposition in the hearing to the bill as drafted, asserting that the language was too broadly written and could have unintended consequences. Other concerns included its potential application to cover bands, but lawmakers assured people that this was not the intention. The bill passed the Tennessee House and Senate with a unanimous, bi-partisan vote including 93 ayes and 0 Noes in the House, and 30 ayes and 0 noes in the Senate. == Passage == By explicitly addressing AI impersonation, the ELVIS Act originated a legal approach to safeguarding personal rights, in the context of digital and technological advancements. It extends protections to an artist's voice and likeness, areas vulnerable to exploitation with the proliferation of AI technologies that occurred in 2023. The legislation received widespread support from the music industry, signaling a significant step forward in the ongoing effort to balance innovation with the protection of individual rights and creative integrity. It was reported as underscoring Tennessee's commitment to its musical heritage and showed the state as a leader in adapting copyright and privacy protections to the modern technological landscape. Artists including Chris Janson and Luke Bryan appeared at the signing ceremony hosted at Robert's Western World to support the new law and commemorate its passing. == Legal precedent == The ELVIS Act was reported as representing a development in the discourse surrounding AI, intellectual property, and personal rights. It was hoped by proponents to set a precedent for future legislative efforts both within and beyond Tennessee, offering a model for how states and potentially the federal government could address similar challenges. As AI technology continues to evolve, the act represents a foundational framework for protecting the authenticity and rights of artists, ensuring contributions remain protected. The act prohibits usage of AI to clone the voice of an artist without consent and can be criminally enforced as a Class A misdemeanor. This legislation's success was hoped by its supporters to inspire similar actions in other states, contributing to a unified approach to copyright and privacy in the digital age. Such a national response would reinforce the importance of safeguarding artists' rights against unauthorized use of their voices and likenesses.
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Sense Networks

Sense Networks is a New York City based company with a focus on applications that analyze big data from mobile phones, carrier networks, and taxicabs, particularly by using machine learning technology to make sense of large amounts of location (latitude/longitude) data. In 2009, Sense was named one of "The 25 Most Intriguing Startups in the World" by Bloomberg Businessweek and was called "The Next Google" on the cover of Newsweek. In 2014, Sense Networks was acquired by YP, "the local search and advertising company owned by Cerberus Capital Management and AT&T." It was subsequently sold off to Verve in 2017 == History == Sense Networks was founded by Greg Skibiski in February 2006 (2003?) near his home in Northampton, Massachusetts. After establishing an office in NoHo, New York City near Silicon Alley, Skibiski recruited Alex Pentland, Director of Human Dynamics Research and former Academic Head of the MIT Media Lab, Tony Jebara, Associate Professor and Head of the Machine Learning Laboratory at Columbia University, and Christine Lemke, who would later become co-founders. Sense Networks investors include Intel Capital, Javelin Venture Partners, and Kenan Altunis. Founder Greg Skibiski was pushed out by lead investor Intel Capital in November 2009 following the company's B round of financing. During the same week, the company won the Emerging Communications Conference "Company to Watch" Award. The company has three published patent applications for analyzing sensor data streams: System and Method of Performing Location Analytics (US 20090307263), Comparing Spatial-Temporal Trails in Location Analytics (US 20100079336), and Anomaly Detection in Sensor Analytics (US 20100082301). The company was acquired by the Yellow Pages in 2014. This is a marketing conglomerate under AT&T and Cerberus Capital Management. == Products and services == The Citysense consumer application that shows hotspots of human activity in real-time from mobile phone location and taxicab GPS data was named by ReadWriteWeb (in The New York Times) as "Top 10 Internet of Things Products of 2009". The Cabsense consumer application that shows the best place to catch a New York City taxicab based on GPS data from the vehicle was launched in March 2010. The Macrosense platform is for mobile application providers and mobile phone carriers to analyze billions of customer location data points for predictive analytics in advertising and churn management applications. == Privacy and data ownership == The company allows users to opt-out of their service through their website, and users may monitor their profile through their application. The company does not collect identifiable data (such as phone numbers or names); it collects data received from cellphone to construct anonymous profiles of consumers. This anonymous data/profiles may then be sold to third parties. The company's privacy and data ownership policies are based on The New Deal on Data, as advocated by Alex "Sandy" Pentland, head of the Human Dynamics group at MIT.
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Jeremy Renner Official

Jeremy Renner Official (or Jeremy Renner on the Google Play Store) was a mobile app created by American actor Jeremy Renner. He created the app in March 2017 to hear the input and comments of his fans. The app was shut down in September 2019 in part due to the frequent bullying and trolling that the platform had experienced. The app featured optional microtransactions, with some ranging up to roughly US$400 despite the app itself being free. Upon shutting down the app, Renner issued a mass-refund for the collectible "stars" in the app for purchases made within the last ninety days, from the day the announcement was posted. He then posted an apology to the app itself, and the app was deleted from both the Google Play Store and the App Store shortly after. == Usage == Upon downloading the app, the user was faced with a video of Renner speaking about his fans and superfans, regular giveaways, and real-life updates. While the app was active, Renner posted regular questions and comments for fans. Renner occasionally livestreamed about his work and day-to-day life. The community developed to include memes, selfies, and a "Happy Rennsday" event on Wednesdays. == History == === 2017–2019 === The app launched in March 2017 with a promotional contest. Renner's fans were encouraged to download the app and create comments about being Renner's biggest fan; Renner would then choose a winner and transport the winner and a guest to have lunch with him at the Calgary Expo. In the first few months Renner teased behind-the-scenes of projects he was working on, which he now sporadically does on Instagram. The app was similarly designed to Instagram as well, with a near identically styled layout. Around midway through 2019, a hoax account of Renner was made to mock the celebrity, joking about masturbating to porn and defending another hoax account of Casey Anthony. FastCompany wrote extensively about Renner's app in April 2019, calling it "a surprising new kind of social media". The Ringer stated "Jeremy Renner's Jeremy Renner app is the Jeremy Renner of apps." === After deletion (2019–2020) === After the shutdown of the app, a comedy-based pseudo-app with modular endings was released, called "The Jeremy Renner App Experience", in which the player plays as Jeremy Renner on the day of the Jeremy Renner Official app's shutdown. The app details several different choices on how Renner handles the situation. A six-part podcast was also created to mock the app's deletion, called The Renner Files, featuring Carolyn Goldfarb and Sarah Ramos. == Controversies == === Marketing === One of the main controversies of Renner's app was its marketing. The app's developers, Escapex, specialized in and grew famous for making similar monetized apps for celebrities. The marketing campaign was based on direct contact with Renner, whose chances were increased with regular payments for "stars", although very few encounters seemed to happen with Renner himself. The multiple problems with the app led the CEO of Escapex, Sephi Shapira, to call the app a "freak situation", and added "Am I concerned about this? Not more than I'm concerned about 50 other things I'm dealing with as a startup company." Along with the marketing failures, the app was seen as misrepresenting itself as seemingly erotic with some advertisements featuring Renner suggestively staring at the camera, despite the actual app being initially considered safe for children. === Harassment === After its release in 2017, the app was met with waves of harassment and bullying by many users on the app, most frequently by using impersonation — referenced in Renner's apology/deletion notice. Some death threats were made across the app by fraud accounts pretending to be several controversial celebrities, including O. J. Simpson and Casey Anthony. As early as October 2017, there were claims of censorship, bullying, and "contest-rigging". In September 2019, comedian Stefan Heck publicized his discovery of the fact that replies through the app appeared as if they were sent by Renner himself in push notifications. After several users abused this feature, Renner asked Escapex to shut down the app.
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Early-exit network

Early-exit networks are a class of dynamic neural networks designed for efficient inference by allowing models to make confident predictions at intermediate layers, rather than processing the full network. Early-exit mechanisms are methods for deep neural networks that add intermediate classifiers, allowing inference to stop at earlier layers for inputs assessed as low uncertainty. Decisions to exit are typically based on confidence measures such as softmax-derived scores, classification margins, or entropy-based criteria, with the goal of reducing computational cost. These approaches are commonly paired with specialized training procedures and system-level optimizations to improve efficiency while preserving accuracy. The main idea behind the technology is to stop excessive calculations when a good answer can already be given with a high degree of probability, which can save both computation and time. Early-exit networks have also been extended with expert-based exit criteria, where intermediate classifiers are treated as multiple “experts” whose predictions and confidence scores can be aggregated to decide whether to stop computation early. Hardware implementations are also being developed.
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Clinical quality management system

Clinical quality management systems (CQMS) are systems used in the life sciences sector (primarily in the pharmaceutical, biologics and medical device industries) designed to manage quality management best practices throughout clinical research and clinical study management. A CQMS system is designed to manage all of the documents, activities, tasks, processes, quality events, relationships, audits and training that must be administered and controlled throughout the life of a clinical trial. The premise of a CQMS is to bring together the activities led by two sectors of clinical research, Clinical Quality and Clinical Operations, to facilitate cross-functional activities to improve efficiencies and transparency and to encourage the use of risk mitigation and risk management practices at the clinical study level. Based on the principles of quality management systems (QMS) which are used in many industries to create a framework for defining and delivering quality outcomes, managing risk, and continual improvement. Many guidelines and governance bodies have been established to ensure a common approach within a given industry to a set of parameters used to identify the minimally acceptable standard for that industry. The pharmaceutical industry is no exception, with several trade groups (e.g. PhRMA, EFPIA, RQA, etc.) coming together to enhance collaboration. However, as noted by the Academy of Medical Sciences, there are increasingly complex and bureaucratic legal and ethical frameworks that innovators must work within to develop new medicines for patients. The historical pharmaceutical QMS applies primarily to good manufacturing practice as described in existing ISO (International Organization for Standardization) and ICH (International Committee on Harmonization) guidelines. "Good Manufacturing Practices (GMP) relate to quality control and quality assurance enabling companies in the pharmaceutical sector to minimize or eliminate instances of contamination, mix-ups, and errors. This in turn, protects the customer from purchasing a product which is ineffective or even dangerous." These standards have historically been applied to the manufacturing environment, appropriate to how they have been written. However, according to FDA as well as other regulatory bodies, "Implementation of ICH Q10 throughout the product lifecycle should facilitate innovation and continual improvement", implying that the same standards that apply to the manufacturing environment should also be applied to the clinical research space, earlier in the lifecycle of an investigational or marketed product. Accordingly, a CQMS is any system developed to apply these principles to clinical operations within an organization.
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