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  • International Clinical Trials Registry Platform

    International Clinical Trials Registry Platform

    The International Clinical Trials Registry Platform (ICTRP) is a platform for the registration of clinical trials operated by the World Health Organization. The ICTRP combines data from multiple cooperating clinical trials registries to generate a global view of clinical trials worldwide, with a search portal that allows access to the entire dataset. It requires a minimum standard set of database fields, the WHO Trial Registration Data Set, to be present for a trial to be registered. All entries are given a Universal Trial Number (UTN) that identifies them uniquely. The organization has sought to assist various national governments in establishing their own clinical trials databases. It combines data from the following primary registries and data providers: Australian New Zealand Clinical Trials Registry (ANZCTR) Brazilian Clinical Trials Registry (ReBec) Chinese Clinical Trial Registry (ChiCTR) Clinical Research Information Service (CRiS), Republic of Korea ClinicalTrials.gov Clinical Trials Information System (CTIS), European Medicines Agency Clinical Trials Registry - India (CTRI) Cuban Public Registry of Clinical Trials (RPCEC) EU Clinical Trials Register (EU-CTR) German Clinical Trials Register (DRKS) Iranian Registry of Clinical Trials (IRCT) ISRCTN (UK) International Traditional Medicine Clinical Trial Registry (ITMCTR) Japan Registry of Clinical Trials (jRCT) Japan Primary Registries Network (JPRN) Lebanese Clinical Trials Registry (LBCTR) Overview of Medical Research in the Netherlands (OMON) Thai Clinical Trials Registry (TCTR) Pan African Clinical Trial Registry (PACTR) Peruvian Clinical Trial Registry (REPEC) Sri Lanka Clinical Trials Registry (SLCTR)

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  • List of algorithms

    List of algorithms

    An algorithm is a fundamental set of rules or defined procedures that are typically designed and used to be a simpler way to solve a specific problem or a broad set of problems. Simply speaking, algorithms define different processes, sets of rules and regulations, or methodologies that are to be followed through in calculations, data processing, data mining, pattern recognition, automated reasoning or other problem-solving operations. With the increasing automation of services, more and more decisions are being made by algorithms. Some general examples are risk assessments, anticipatory policing, and pattern recognition technology. The following is a list of well-known algorithms. == Automated planning == == Combinatorial algorithms == === General combinatorial algorithms === Brent's algorithm: finds a cycle in function value iterations using only two iterators Floyd's cycle-finding algorithm: finds a cycle in function value iterations Gale–Shapley algorithm: solves the stable matching problem Pseudorandom number generators (uniformly distributed—see also List of pseudorandom number generators for other PRNGs with varying degrees of convergence and varying statistical quality): ACORN generator Blum Blum Shub Lagged Fibonacci generator Linear congruential generator Mersenne Twister === Graph algorithms === Blossom algorithm: algorithm for constructing maximum-cardinality matching on graphs. Coloring algorithm: algorithms for graph (vertex or edge) coloring (subject to constraints, e.g. proper coloring or list coloring) Hopcroft–Karp algorithm: convert a bipartite graph to a maximum-cardinality matching Hungarian algorithm: algorithm for finding a perfect matching Prüfer coding: conversion between a labeled tree and its Prüfer sequence Tarjan's off-line lowest common ancestors algorithm: computes lowest common ancestors for pairs of nodes in a tree Topological sort: finds linear order of nodes (e.g. jobs) based on their dependencies. ==== Graph drawing ==== Coin graph drawing algorithms for finite connected planar graphs (approximately computing the theoretical circle-packing given by the Koebe-Andreev-Thurston theorem). See also Fáry's theorem on straight-line drawings of planar graphs. Force-based algorithms (also known as force-directed algorithms or spring-based algorithms) Spectral layout ==== Network theory ==== Network analysis Link analysis Girvan–Newman algorithm: detect communities in complex systems Web link analysis Hyperlink-Induced Topic Search (HITS) (also known as Hubs and authorities) PageRank TrustRank Flow networks Dinic's algorithm: is a strongly polynomial algorithm for computing the maximum flow in a flow network. Edmonds–Karp algorithm: implementation of Ford–Fulkerson Ford–Fulkerson algorithm: computes the maximum flow in a graph Karger's algorithm: a Monte Carlo method to compute the minimum cut of a connected graph Push–relabel algorithm: computes a maximum flow in a graph ==== Routing for graphs ==== Edmonds' algorithm (also known as Chu–Liu/Edmonds' algorithm): find maximum or minimum branchings Euclidean minimum spanning tree: algorithms for computing the minimum spanning tree of a set of points in the plane Longest path problem: find a simple path of maximum length in a given graph Minimum spanning tree Borůvka's algorithm Kruskal's algorithm Prim's algorithm Reverse-delete algorithm Nonblocking minimal spanning switch say, for a telephone exchange Shortest path problem Bellman–Ford algorithm: computes shortest paths in a weighted graph (where some of the edge weights may be negative) Dijkstra's algorithm: computes shortest paths in a graph with non-negative edge weights Floyd–Warshall algorithm: solves the all pairs shortest path problem in a weighted, directed graph Johnson's algorithm: all pairs shortest path algorithm in sparse weighted directed graph Transitive closure problem: find the transitive closure of a given binary relation Traveling salesman problem Christofides algorithm Nearest neighbour algorithm Vehicle routing problem Clarke and Wright Saving algorithm Warnsdorff's rule: a heuristic method for solving the Knight's tour problem ==== Graph search ==== A: special case of best-first search that uses heuristics to improve speed B: a best-first graph search algorithm that finds the least-cost path from a given initial node to any goal node (out of one or more possible goals) Backtracking: abandons partial solutions when they are found not to satisfy a complete solution Beam search: is a heuristic search algorithm that is an optimization of best-first search that reduces its memory requirement Beam stack search: integrates backtracking with beam search Best-first search: traverses a graph in the order of likely importance using a priority queue Bidirectional search: find the shortest path from an initial vertex to a goal vertex in a directed graph Breadth-first search: traverses a graph level by level Brute-force search: an exhaustive and reliable search method, but computationally inefficient in many applications D: an incremental heuristic search algorithm Depth-first search: traverses a graph branch by branch Dijkstra's algorithm: a special case of A for which no heuristic function is used General Problem Solver: a seminal theorem-proving algorithm intended to work as a universal problem solver machine. Iterative deepening depth-first search (IDDFS): a state space search strategy Jump point search: an optimization to A which may reduce computation time by an order of magnitude using further heuristics Lexicographic breadth-first search (also known as Lex-BFS): a linear time algorithm for ordering the vertices of a graph SSS: state space search traversing a game tree in a best-first fashion similar to that of the A search algorithm Uniform-cost search: a tree search that finds the lowest-cost route where costs vary ==== Subgraphs ==== Cliques Bron–Kerbosch algorithm: a technique for finding maximal cliques in an undirected graph MaxCliqueDyn maximum clique algorithm: find a maximum clique in an undirected graph Strongly connected components Kosaraju's algorithm Path-based strong component algorithm Tarjan's strongly connected components algorithm Subgraph isomorphism problem === Sequence algorithms === ==== Approximate sequence matching ==== Bitap algorithm: fuzzy algorithm that determines if strings are approximately equal. Phonetic algorithms Daitch–Mokotoff Soundex: a Soundex refinement which allows matching of Slavic and Germanic surnames Double Metaphone: an improvement on Metaphone Match rating approach: a phonetic algorithm developed by Western Airlines Metaphone: an algorithm for indexing words by their sound, when pronounced in English NYSIIS: phonetic algorithm, improves on Soundex Soundex: a phonetic algorithm for indexing names by sound, as pronounced in English String metrics: computes a similarity or dissimilarity (distance) score between two pairs of text strings Damerau–Levenshtein distance: computes a distance measure between two strings, improves on Levenshtein distance Dice's coefficient (also known as the Dice coefficient): a similarity measure related to the Jaccard index Hamming distance: sum number of positions which are different Jaro–Winkler distance: is a measure of similarity between two strings Levenshtein edit distance: computes a metric for the amount of difference between two sequences Trigram search: search for text when the exact syntax or spelling of the target object is not precisely known ==== Selection algorithms ==== Introselect Quickselect ==== Sequence search ==== Linear search: locates an item in an unsorted sequence Selection algorithm: finds the kth largest item in a sequence Sorted lists Binary search algorithm: locates an item in a sorted sequence Eytzinger binary search: cache friendly binary search algorithm Fibonacci search technique: search a sorted sequence using a divide and conquer algorithm that narrows down possible locations with the aid of Fibonacci numbers Jump search (or block search): linear search on a smaller subset of the sequence Predictive search: binary-like search which factors in magnitude of search term versus the high and low values in the search. Sometimes called dictionary search or interpolated search. Uniform binary search: an optimization of the classic binary search algorithm Ternary search: a technique for finding the minimum or maximum of a function that is either strictly increasing and then strictly decreasing or vice versa ==== Sequence merging ==== k-way merge algorithm Simple merge algorithm Union (merge, with elements on the output not repeated) ==== Sequence permutations ==== Fisher–Yates shuffle (also known as the Knuth shuffle): randomly shuffle a finite set Heap's permutation generation algorithm: interchange elements to generate next permutation Schensted algorithm: constructs a pair of Young tableaux from a permutation Steinhaus–Johnson–Trotter algorithm (also known as the Johnson–Trotter algorithm):

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  • CENDI

    CENDI

    CENDI (Commerce, Energy, NASA, Defense Information Managers Group) is an interagency group of senior Scientific and Technical Information (STI) managers from 14 United States federal agencies. CENDI managers cooperate by exchanging information and ideas, collaborating to address common issues, and undertaking joint initiatives. CENDI's accomplishments range from impacting federal information policy to educating a broad spectrum of stakeholders on all aspects of federal STI systems, including its value to research and the taxpayer, and to operational improvements in agency and interagency STI operations. == History == CENDI traces its roots to the Committee on Scientific and Technical Information (COSATI) of the Federal Council on Science and Technology. COSATI was established in the early 1960s to coordinate the management of the results from the U.S. government's increasing commitment to scientific research and technology development. The scientific and technical information (STI) managers of the government's major research and development (R&D) agencies worked within COSATI to standardize guidelines for cataloging and indexing technical reports. COSATI ceased formal operations in the early 1970s. To continue the cooperation begun under COSATI, managers of agency STI programs from Commerce (National Technical Information Service), Energy (Office of Scientific and Technical Information), NASA (HQ/STI Division), and Defense (Defense Technical Information Center) began meeting periodically to discuss common topics and stimulate more effective cooperation. In 1985, a Memorandum of Understanding was signed by the four charter agencies and CENDI was established. From this small core of STI managers, CENDI has grown to its current membership, which represents the major science agencies, the national libraries, and agencies involved in the dissemination and long-term management of scientific and technical information. The vision of CENDI is to facilitate cooperative enterprise where capabilities are shared and challenges are faced together so that the sum of the accomplishments is greater than each individual agency can achieve on its own amongst federal STI agencies. The abbreviation CENDI refers to the "Commerce, Energy, NASA, Defense Information Managers Group". == Membership == New members from other federal R&D information organizations may be admitted by unanimous agreement of the members. However, it is the intent of the group that membership in CENDI should remain small and focus on organizations with STI or supporting responsibilities. Each agency provides funding to CENDI. == Members == The members of CENDI are: Defense Technical Information Center (United States Department of Defense) Office of Research and Development and Office of Environmental Information (United States Environmental Protection Agency) Government Printing Office Library of Congress NASA Scientific and Technical Information Program National Agricultural Library (United States Department of Agriculture) National Archives and Records Administration National Library of Education (United States Department of Education) National Library of Medicine (United States Department of Health and Human Services) National Science Foundation National Technical Information Service (United States Department of Commerce) National Transportation Library (United States Department of Transportation) Office of Scientific and Technical Information (United States Department of Energy) USGS/Biological Resources Discipline (United States Department of the Interior) == Mission and operation == CENDI's mission is to help improve the productivity of federal science- and technology-based programs through effective scientific, technical, and related information support systems. In fulfilling its mission, CENDI agencies play an important role in addressing science- and technology-based national priorities and strengthening U.S. competitiveness. === Goals === STI Coordination and Leadership: Provide coordination and leadership for information exchange on important STI policy issues. Improvement of STI Systems: Promote the development of improved STI systems through the productive interrelationship of content and technology. STI Understanding: Promote better understanding of STI and STI management. === Principals and Alternates === CENDI is made up of senior federal STI managers and each organization appoints a Principal representative. This person is the point of contact for that organization within CENDI. Each Principal has an Alternate. The Principals and Alternates comprise the main group that meets on a regular basis, usually every other month. === Secretariat === A Tennessee-based information management company, -- Information International Associates, Inc., currently serves as the CENDI Secretariat. The Secretariat provides day-to-day operations to CENDI. The Secretariat prepares the necessary materials for the Principals' meetings, provides support for the working group and task group meetings, assists in developing papers, and maintains the CENDI files and outreach tools. === Task Groups and Working Groups === The chair(s) of a working group is appointed by the Principals and has the overall responsibility for the group's activities. The Secretariat provides support at the request of the Working Group chair(s). The Working Groups and Task Groups that are currently operating are: Copyright and Intellectual Property Working Group Distribution Markings Task Group Digital Preservation Task Group Digitization Specifications Task Group Image Metadata Task Group Science.gov (see below) STI Policy Working Group Terminology Resources Task Group === Science.gov and Worldwidescience.org === In 2001, in response to the April 2001 workshop on "Strengthening the Public Information Infrastructure for Science", and taking into consideration a request from Firstgov (now USA.gov) to develop specialized topical portals, CENDI formed an alliance to develop an interagency website for access to STI. This website, called Science.gov, is a one-stop source of STI, including both selected, authoritative government websites and deep Web databases of technical reports, journal articles, conference proceedings, and other published materials. Through the volunteer efforts of members and involving over 100 staff, content and architecture is developed for the site. The Science.gov website is hosted by the Department of Energy (DOE) Office of Scientific and Technical Information (OSTI). The site was formally launched in December 2002. As a result of the success of Science.gov, under DOE leadership and in cooperation with the International Council of Scientific and Technical Information, a worldwide coordination across national portals called WorldWideScience was launched in 2008. === Work with non-member organizations === CENDI works with several cooperating non-member organizations on a regular basis. These agencies are in academia, federal government, legal and policy analysis, international, non-governmental, and private organizations.

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  • Literature review

    Literature review

    A literature review is an overview of previously published works on a particular topic. The term can refer to a full scholarly paper or a section of a scholarly work such as books or articles. Either way, a literature review provides the researcher/author and the audiences with general information of an existing knowledge of a particular topic. A good literature review has a proper research question, a proper theoretical framework, and/or a chosen research method. It serves to situate the current study within the body of the relevant literature and provides context for the reader. In such cases, the review usually precedes the methodology and results sections of the work. Producing a literature review is often part of a graduate and post-graduate requirement, included in the preparation of a thesis, dissertation, or a journal article. Literature reviews are also common in a research proposal or prospectus (the document approved before a student formally begins a dissertation or thesis). A literature review can be a type of a review article. In this sense, it is a scholarly paper that presents the current knowledge including substantive findings as well as theoretical and methodological contributions to a particular topic. Literature reviews are secondary sources and do not report new or original experimental work. Most often associated with academic-oriented literature, such reviews are found in academic journals and are not to be confused with book reviews, which may also appear in the same publication. Literature reviews are a basis for research in nearly every academic field. == Types == Since the concept of a systematic review was formalized in the 1970s, a basic division among types of reviews is the dichotomy of narrative reviews versus systematic reviews. The main types of narrative reviews are evaluative, exploratory, and instrumental. A fourth type of review of literature (the scientific literature) is the systematic review but it is not called a literature review, which absent further specification, conventionally refers to narrative reviews. A systematic review focuses on a specific research question to identify, appraise, select, and synthesize all high-quality research evidence and arguments relevant to that question. A meta-analysis is typically a systematic review using statistical methods to effectively combine the data used on all selected studies to produce a more reliable result. Torraco (2016) describes an integrative literature review. The purpose of an integrative literature review is to generate new knowledge on a topic through the process of review, critique, and synthesis of the literature under investigation. George et al (2023) offer an extensive overview of review approaches. They also propose a model for selecting an approach by looking at the purpose, object, subject, community, and practices of the review. They describe six different types of review, each with their own unique purposes: Exploratory or scoping reviews focus on breadth as opposed to depth Systematic or integrative reviews integrate empirical studies on a topic Meta-narrative reviews are qualitative and use literature to compare research or practice communities Problematizing or critical reviews propose new perspectives on a concept by association with other literature Meta-analyses and meta-regressions integrate quantitative studies and identify moderators Mixed research syntheses combine other review approaches in the same paper == Process and product == Shields and Rangarajan (2013) distinguish between the process of reviewing the literature and a finished work or product known as a literature review. The process of reviewing the literature is often ongoing and informs many aspects of the empirical research project. The process of reviewing the literature requires different kinds of activities and ways of thinking. Shields and Rangarajan (2013) and Granello (2001) link the activities of doing a literature review with Benjamin Bloom's revised taxonomy of the cognitive domain (ways of thinking: remembering, understanding, applying, analyzing, evaluating, and creating). === Use of artificial intelligence in a literature review === Artificial intelligence (AI) is reshaping traditional literature reviews across various disciplines. Generative pre-trained transformers, such as ChatGPT, are often used by students and academics for review purposes. Since 2023, an increasing number of tools powered by large language models and other artificial intelligence technologies have been developed to assist, automate, or generate literature reviews. Nevertheless, the employment of ChatGPT in academic reviews is problematic due to ChatGPT's propensity to "hallucinate". In response, efforts are being made to mitigate these hallucinations through the integration of plugins. For instance, Rad et al. (2023) used ScholarAI for review in cardiothoracic surgery.

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  • Contract management software

    Contract management software

    Contract management software constitutes software and associated data management used to support contract management, contract lifecycle management, and contractor management on projects in the procurement of goods and services. It may be used together with project management software. == History == Historically, contract management was seen as a "paper-intensive" process. Early steps from the early 2000's reported by the Aberdeen Group required extensive data conversion work to enable documents to be handled electronically. With the adoption of the European Union's General Data Protection Regulation (GDPR) in 2016, companies needed to take additional steps in regards to contract management. Each data responsible entity was obliged to sign data processing agreements (DPAs) with the various vendors, who treat personal data on behalf of the data responsible. DPAs need to be regularly controlled, adjusted and renewed, which adds an extra agreement to such vendors or at least an extra DPA addendum to each agreement. By 2018, Ardent Partner's research had found that software used for automating contract management activities was being more extensively used among major companies or businesses with "Best-in-Class" procurement teams. Contract management process automation was found to be closely linked with more effective internal business collaboration, standardization and risk management. == Advantages and key functions == Using contract management software can have multiple benefits compared to manually managing paper contracts. This software can help keep track of multiple activities and can have features for automating administration, ensuring compliance, monitoring risk, running reports and triggering alerts. In addition to these types of features, contract management software systems provide a centralized repository for employees to quickly access all contracts worldwide in one place. Contract management software is produced by many companies, working on a range of scales and offering varying degrees of customizability. Basic functions should include the ability to store contract documents, track changes to contract documents, search documents for a particular criterion, send key date alerts and to report required aspects of the contract. Other functions include managing a new contract request, capturing related data, following a document through a review and approval process, and collecting digital signatures. Contract management software may also be an aid to project portfolio management and spend analysis, and may also monitor KPIs. Leading contract management software provides contract visibility, monitoring, and compliance to automate and streamline the contract lifecycle process. Contract management software which uses artificial intelligence (AI) can identify contract types based on pattern recognition. AI contracting software trains its algorithms on a set of contract data to recognize patterns and extract variables such as clauses, dates, and parties. It also offers simple prediction capabilities, by sorting through a large volume of contracts and flagging individual contracts based on specified criteria. AI software can also read contracts in multiple formats and languages, extract contract data, and provide analytics. It can reduce the risk of human error in contract drafting and review. A centralized repository provides a critical advantage allowing for all contract documents to be stored within one location. Having contracts stored in multiple locations can delay and interrupt the contracting process. == Contract risk management software (CRMS) for capital projects == Very large enterprises, such as capital expenditure (capex) projects, involve multiple parties and high risk and uncertainty. They are unlike traditional operating contracts in that they are subject to shared deadlines in unique situations. As the complexity of these unique projects increases, the relationships between parties become more important. This requires contract management software, or contract risk management software (CRMS), to become more dynamic and responsive. The terms of these capex contracts necessarily involve assumptions at the start of the process and are likely to change over the lifetime of the project lifecycle. For this reason, CRMS must be capable of recording one single instance of agreed changes to contract terms and incorporating these changes in an auditable and legally robust way. With multiple decision makers involved, CRMS should also make accountability more transparent and enable faster decisions about variation proposals.

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  • Read–write conflict

    Read–write conflict

    In computer science, in the field of databases, read–write conflict, also known as unrepeatable reads, is a computational anomaly associated with interleaved execution of transactions. Specifically, a read–write conflict occurs when a "transaction requests to read an entity for which an unclosed transaction has already made a write request." Given a schedule S S = [ T 1 T 2 R ( A ) R ( A ) W ( A ) C o m . R ( A ) W ( A ) C o m . ] {\displaystyle S={\begin{bmatrix}T1&T2\\R(A)&\\&R(A)\\&W(A)\\&Com.\\R(A)&\\W(A)&\\Com.&\end{bmatrix}}} In this example, T1 has read the original value of A, and is waiting for T2 to finish. T2 also reads the original value of A, overwrites A, and commits. However, when T1 reads from A, it discovers two different versions of A, and T1 would be forced to abort, because T1 would not know what to do. This is an unrepeatable read. This could never occur in a serial schedule, in which each transaction executes in its entirety before another begins. Strict two-phase locking (Strict 2PL) or Serializable Snapshot Isolation (SSI) prevent this conflict. == Real-world example == Alice and Bob are using a website to book tickets for a specific show. Only one ticket is left for the specific show. Alice signs on first to see that only one ticket is left, and finds it expensive. Alice takes time to decide. Bob signs on and also finds one ticket left, and orders it instantly. Bob purchases and logs off. Alice decides to buy a ticket, to find there are no tickets. This is a typical read–write conflict situation.

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  • Communication-avoiding algorithm

    Communication-avoiding algorithm

    Communication-avoiding algorithms minimize movement of data within a memory hierarchy for improving its running-time and energy consumption. These minimize the total of two costs (in terms of time and energy): arithmetic and communication. Communication, in this context refers to moving data, either between levels of memory or between multiple processors over a network. It is much more expensive than arithmetic. == Formal theory == === Two-level memory model === A common computational model in analyzing communication-avoiding algorithms is the two-level memory model: There is one processor and two levels of memory. Level 1 memory is infinitely large. Level 0 memory ("cache") has size M {\displaystyle M} . In the beginning, input resides in level 1. In the end, the output resides in level 1. Processor can only operate on data in cache. The goal is to minimize data transfers between the two levels of memory. === Matrix multiplication === Corollary 6.2: More general results for other numerical linear algebra operations can be found in. The following proof is from. == Motivation == Consider the following running-time model: Measure of computation = Time per FLOP = γ Measure of communication = No. of words of data moved = β ⇒ Total running time = γ·(no. of FLOPs) + β·(no. of words) From the fact that β >> γ as measured in time and energy, communication cost dominates computation cost. Technological trends indicate that the relative cost of communication is increasing on a variety of platforms, from cloud computing to supercomputers to mobile devices. The report also predicts that gap between DRAM access time and FLOPs will increase 100× over coming decade to balance power usage between processors and DRAM. Energy consumption increases by orders of magnitude as we go higher in the memory hierarchy. United States president Barack Obama cited communication-avoiding algorithms in the FY 2012 Department of Energy budget request to Congress: New Algorithm Improves Performance and Accuracy on Extreme-Scale Computing Systems. On modern computer architectures, communication between processors takes longer than the performance of a floating-point arithmetic operation by a given processor. ASCR researchers have developed a new method, derived from commonly used linear algebra methods, to minimize communications between processors and the memory hierarchy, by reformulating the communication patterns specified within the algorithm. This method has been implemented in the TRILINOS framework, a highly-regarded suite of software, which provides functionality for researchers around the world to solve large scale, complex multi-physics problems. == Objectives == Communication-avoiding algorithms are designed with the following objectives: Reorganize algorithms to reduce communication across all memory hierarchies. Attain the lower-bound on communication when possible. The following simple example demonstrates how these are achieved. === Matrix multiplication example === Let A, B and C be square matrices of order n × n. The following naive algorithm implements C = C + A B: for i = 1 to n for j = 1 to n for k = 1 to n C(i,j) = C(i,j) + A(i,k) B(k,j) Arithmetic cost (time-complexity): n2(2n − 1) for sufficiently large n or O(n3). Rewriting this algorithm with communication cost labelled at each step for i = 1 to n {read row i of A into fast memory} - n2 reads for j = 1 to n {read C(i,j) into fast memory} - n2 reads {read column j of B into fast memory} - n3 reads for k = 1 to n C(i,j) = C(i,j) + A(i,k) B(k,j) {write C(i,j) back to slow memory} - n2 writes Fast memory may be defined as the local processor memory (CPU cache) of size M and slow memory may be defined as the DRAM. Communication cost (reads/writes): n3 + 3n2 or O(n3) Since total running time = γ·O(n3) + β·O(n3) and β >> γ the communication cost is dominant. The blocked (tiled) matrix multiplication algorithm reduces this dominant term: ==== Blocked (tiled) matrix multiplication ==== Consider A, B and C to be n/b-by-n/b matrices of b-by-b sub-blocks where b is called the block size; assume three b-by-b blocks fit in fast memory. for i = 1 to n/b for j = 1 to n/b {read block C(i,j) into fast memory} - b2 × (n/b)2 = n2 reads for k = 1 to n/b {read block A(i,k) into fast memory} - b2 × (n/b)3 = n3/b reads {read block B(k,j) into fast memory} - b2 × (n/b)3 = n3/b reads C(i,j) = C(i,j) + A(i,k) B(k,j) - {do a matrix multiply on blocks} {write block C(i,j) back to slow memory} - b2 × (n/b)2 = n2 writes Communication cost: 2n3/b + 2n2 reads/writes << 2n3 arithmetic cost Making b as large possible: 3b2 ≤ M we achieve the following communication lower bound: 31/2n3/M1/2 + 2n2 or Ω (no. of FLOPs / M1/2) == Previous approaches for reducing communication == Most of the approaches investigated in the past to address this problem rely on scheduling or tuning techniques that aim at overlapping communication with computation. However, this approach can lead to an improvement of at most a factor of two. Ghosting is a different technique for reducing communication, in which a processor stores and computes redundantly data from neighboring processors for future computations. Cache-oblivious algorithms represent a different approach introduced in 1999 for fast Fourier transforms, and then extended to graph algorithms, dynamic programming, etc. They were also applied to several operations in linear algebra as dense LU and QR factorizations. The design of architecture specific algorithms is another approach that can be used for reducing the communication in parallel algorithms, and there are many examples in the literature of algorithms that are adapted to a given communication topology.

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  • Kinodynamic planning

    Kinodynamic planning

    In robotics and motion planning, kinodynamic planning is a class of problems for which velocity, acceleration, and force/torque bounds must be satisfied, together with kinematic constraints such as avoiding obstacles. The term was coined by Bruce Donald, Pat Xavier, John Canny, and John Reif. Donald et al. developed the first polynomial-time approximation schemes (PTAS) for the problem. By providing a provably polynomial-time ε-approximation algorithm, they resolved a long-standing open problem in optimal control. Their first paper considered time-optimal control ("fastest path") of a point mass under Newtonian dynamics, amidst polygonal (2D) or polyhedral (3D) obstacles, subject to state bounds on position, velocity, and acceleration. Later they extended the technique to many other cases, for example, to 3D open-chain kinematic robots under full Lagrangian dynamics. == Modern approaches == Since the foundational theoretical work of the 1990s, the field has evolved significantly with new algorithmic approaches that address the computational and practical limitations of early methods. === Sampling-based methods === Many practical heuristic algorithms based on stochastic optimization and iterative sampling have been developed by a wide range of authors to address the kinodynamic planning problem. Popular approaches include extensions of RRT algorithms such as RRT for kinodynamic systems, and sampling-based methods like Model Predictive Path Integral (MPPI) control. These stochastic techniques have been shown to work well in practice and can handle complex, high-dimensional state spaces more efficiently than deterministic methods. However, all motion planning methods are subject to the PSPACE-hardnesss of classical motion planning even without dynamics, which means (assuming the usual structural complexity conjectures) they all can be worst-case exponential-time in the state-space dimension (the number of degrees of freedom). On the other hand, the deterministic methods have provable guarantees of completeness, accuracy, and complexity (for fixed dimension, they are polynomial-time not only in the geometric complexity, but also in ( 1 / ε ) {\displaystyle (1/\varepsilon )} , the closeness of the desired approximation), whereas most of the recent heuristic/stochastic methods sacrifice at least one of these criteria. === Mixed-integer optimization approaches === Recent advances in mixed-integer programming have enabled new deterministic approaches to kinodynamic planning. These methods formulate the planning problem as an optimization task that simultaneously determines the spatial path and control sequence while respecting all kinodynamic constraints. By using techniques such as McCormick envelopes to handle bilinear constraints, these approaches can provide globally optimal solutions with mathematical guarantees while achieving significant computational speedups over traditional methods. === Genetic algorithm approaches === Genetic algorithms have also been adapted for kinodynamic planning, particularly for gradient-free optimization in challenging terrain. These methods use evolutionary computation to optimize trajectories over receding horizons, with specialized mutation operators that ensure vehicle controls remain within operational limits. This approach is particularly useful when dealing with non-differentiable cost functions or when gradient information is unavailable or unreliable. === Three-dimensional terrain planning === The foundational theoretical work of the 1990s was extended to higher degrees of freedom, and even to n {\displaystyle n} -link, 3D open-chain kinematic robots under full Lagrangian dynamics. However, many of the subsequent heuristic techniques (typically employing stochastic optimization) were confined to planar environments. More recent kinodynamic planning has extended beyond these planar environments to handle complex 3D terrains represented as simplicial complexes or triangular meshes. This advancement is particularly important for applications such as autonomous vehicle navigation in off-road environments, where elevation changes and terrain geometry significantly impact vehicle dynamics. These methods must account for pitch angles, surface curvature, and the coupling between terrain geometry and vehicle kinodynamic constraints. == Performance and guarantees == The landscape of performance guarantees in kinodynamic planning has evolved considerably. While early heuristic methods could not guarantee optimality, recent mixed-integer approaches have demonstrated the ability to find globally optimal solutions with proven constraint satisfaction. Experimental comparisons have shown that modern optimization-based planners can achieve execution times several orders of magnitude faster than sampling-based methods while maintaining strict adherence to kinodynamic constraints. However, the choice of method often depends on the specific application requirements. Sampling-based methods remain valuable for their ability to quickly find feasible solutions in high-dimensional spaces and their robustness to modeling uncertainties. Optimization-based methods excel when optimality guarantees and constraint compliance are critical, particularly in safety-critical applications. == Applications == Kinodynamic planning finds applications across numerous domains including: Autonomous vehicles: Path planning for cars, trucks, and other ground vehicles that must respect acceleration, steering, and velocity limits Aerial robotics: Trajectory planning for quadrotors and other unmanned aerial vehicles with dynamic constraints Manipulation: Planning for robotic arms where joint velocities, accelerations, and torques are limited Legged locomotion: Footstep and trajectory planning for walking and running robots Space robotics: Planning under thrust and fuel constraints for spacecraft and rovers

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  • Screenless video

    Screenless video

    Screenless video is any system for transmitting visual information from a video source without the use of a screen. Screenless computing systems can be divided into three groups: Visual Image, Retinal Direct, and Synaptic Interface. == Visual image == Visual Image screenless display includes any image that the eye can perceive. The most common example of Visual Image screenless display is a hologram. In these cases, light is reflected off some intermediate object (hologram, LCD panel, or cockpit window) before it reaches the retina. In the case of LCD panels the light is refracted from the back of the panel, but is nonetheless a reflected source. Google has proposed a similar system to replace the screens of tablet computers and smartphones. == Retinal display == Virtual retinal display systems are a class of screenless displays in which images are projected directly onto the retina. They are distinguished from visual image systems because light is not reflected from some intermediate object onto the retina, it is instead projected directly onto the retina. Retinal Direct systems, once marketed, hold out the promise of extreme privacy when computing work is done in public places because most snooping relies on viewing the same light as the person who is legitimately viewing the screen, and retinal direct systems send light only into the pupils of their intended viewer. == Synaptic interface == Synaptic Interface screenless video does not use light at all. Visual information completely bypasses the eye and is transmitted directly to the brain. While such systems have only been implemented in humans in rudimentary form - for example, displaying single Braille characters to blind people – success has been achieved in sampling usable video signals from the biological eyes of a living horseshoe crab through their optic nerves, and in sending video signals from electronic cameras into the creatures' brains using the same method.

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  • Metadirectory

    Metadirectory

    A metadirectory system provides for the flow of data between one or more directory services and databases in order to maintain synchronization of that data. It is an important part of identity management systems. The data being synchronized typically are collections of entries that contain user profiles and possibly authentication or policy information. Most metadirectory deployments synchronize data into at least one LDAP-based directory server, to ensure that LDAP-based applications such as single sign-on and portal servers have access to recent data, even if the data is mastered in a non-LDAP data source. Metadirectory products support filtering and transformation of data in transit. Most identity management suites from commercial vendors include a metadirectory product, or a user provisioning product.

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  • Point-in-time recovery

    Point-in-time recovery

    Point-in-time recovery (PITR) in the context of computers involves systems, often databases, whereby an administrator can restore or recover a set of data or a particular setting from a time in the past. Note for example Windows's capability to restore operating-system settings from a past date (for instance, before data corruption occurred). Time Machine for macOS provides another example of point-in-time recovery. Once PITR logging starts for a PITR-capable database, a database administrator can restore that database from backups to the state that it had at any time since.

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  • Sequential algorithm

    Sequential algorithm

    In computer science, a sequential algorithm or serial algorithm is an algorithm that is executed sequentially – once through, from start to finish, without other processing executing – as opposed to concurrently or in parallel. The term is primarily used to contrast with concurrent algorithm or parallel algorithm; most standard computer algorithms are sequential algorithms, and not specifically identified as such, as sequentialness is a background assumption. Concurrency and parallelism are in general distinct concepts, but they often overlap – many distributed algorithms are both concurrent and parallel – and thus "sequential" is used to contrast with both, without distinguishing which one. If these need to be distinguished, the opposing pairs sequential/concurrent and serial/parallel may be used. "Sequential algorithm" may also refer specifically to an algorithm for decoding a convolutional code.

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  • Sherwood Applied Business Security Architecture

    Sherwood Applied Business Security Architecture

    SABSA (Sherwood Applied Business Security Architecture) is a model and methodology for developing a risk-driven enterprise information security architecture and service management, to support critical business processes. It was developed independently from the Zachman Framework, but has a similar structure. The primary characteristic of the SABSA model is that everything must be derived from an analysis of the business requirements for security, especially those in which security has an enabling function through which new business opportunities can be developed and exploited. The process analyzes the business requirements at the outset, and creates a chain of traceability through the strategy and concept, design, implementation, and ongoing ‘manage and measure’ phases of the lifecycle to ensure that the business mandate is preserved. Framework tools created from practical experience further support the whole methodology. The model is layered, with the top layer being the business requirements definition stage. At each lower layer a new level of abstraction and detail is developed, going through the definition of the conceptual architecture, logical services architecture, physical infrastructure architecture and finally at the lowest layer, the selection of technologies and products (component architecture). The SABSA model itself is generic and can be the starting point for any organization, but by going through the process of analysis and decision-making implied by its structure, it becomes specific to the enterprise, and is finally highly customized to a unique business model. It becomes in reality the enterprise security architecture, and it is central to the success of a strategic program of information security management within the organization. SABSA is a particular example of a methodology that can be used both for IT (information technology) and OT (operational technology) environments. == SABSA matrix == Note: The above is the original SABSA Matrix, which is still valid today, but it has been expanded by a comprehensive service management matrix and updated in some detail and terminology areas. In the words of David Lynas, SABSA author, "The SABSA Matrix and the SABSA Service Management Matrix have not been updated since the late 90s. We have redesigned them to deliver the improvements your feedback has requested over the years. We have not fundamentally changed the structure or principles of the matrices (very few elements have changed position) but have focused on terminology update and consistency." The new versions can be downloaded (along with the 2009 revision of the SABSA White Paper and other important documents like the SABSA Certification Roadmap) at the SABSA Members' Web Site.

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  • Bartels–Stewart algorithm

    Bartels–Stewart algorithm

    In numerical linear algebra, the Bartels–Stewart algorithm is used to numerically solve the Sylvester matrix equation A X − X B = C {\displaystyle AX-XB=C} . Developed by R.H. Bartels and G.W. Stewart in 1971, it was the first numerically stable method that could be systematically applied to solve such equations. The algorithm works by using the real Schur decompositions of A {\displaystyle A} and B {\displaystyle B} to transform A X − X B = C {\displaystyle AX-XB=C} into a triangular system that can then be solved using forward or backward substitution. In 1979, G. Golub, C. Van Loan and S. Nash introduced an improved version of the algorithm, known as the Hessenberg–Schur algorithm. It remains a standard approach for solving Sylvester equations when X {\displaystyle X} is of small to moderate size. == The algorithm == Let X , C ∈ R m × n {\displaystyle X,C\in \mathbb {R} ^{m\times n}} , and assume that the eigenvalues of A {\displaystyle A} are distinct from the eigenvalues of B {\displaystyle B} . Then, the matrix equation A X − X B = C {\displaystyle AX-XB=C} has a unique solution. The Bartels–Stewart algorithm computes X {\displaystyle X} by applying the following steps: 1.Compute the real Schur decompositions R = U T A U , {\displaystyle R=U^{T}AU,} S = V T B T V . {\displaystyle S=V^{T}B^{T}V.} The matrices R {\displaystyle R} and S {\displaystyle S} are block-upper triangular matrices, with diagonal blocks of size 1 × 1 {\displaystyle 1\times 1} or 2 × 2 {\displaystyle 2\times 2} . 2. Set F = U T C V . {\displaystyle F=U^{T}CV.} 3. Solve the simplified system R Y − Y S T = F {\displaystyle RY-YS^{T}=F} , where Y = U T X V {\displaystyle Y=U^{T}XV} . This can be done using forward substitution on the blocks. Specifically, if s k − 1 , k = 0 {\displaystyle s_{k-1,k}=0} , then ( R − s k k I ) y k = f k + ∑ j = k + 1 n s k j y j , {\displaystyle (R-s_{kk}I)y_{k}=f_{k}+\sum _{j=k+1}^{n}s_{kj}y_{j},} where y k {\displaystyle y_{k}} is the k {\displaystyle k} th column of Y {\displaystyle Y} . When s k − 1 , k ≠ 0 {\displaystyle s_{k-1,k}\neq 0} , columns [ y k − 1 ∣ y k ] {\displaystyle [y_{k-1}\mid y_{k}]} should be concatenated and solved for simultaneously. 4. Set X = U Y V T . {\displaystyle X=UYV^{T}.} === Computational cost === Using the QR algorithm, the real Schur decompositions in step 1 require approximately 10 ( m 3 + n 3 ) {\displaystyle 10(m^{3}+n^{3})} flops, so that the overall computational cost is 10 ( m 3 + n 3 ) + 2.5 ( m n 2 + n m 2 ) {\displaystyle 10(m^{3}+n^{3})+2.5(mn^{2}+nm^{2})} . === Simplifications and special cases === In the special case where B = − A T {\displaystyle B=-A^{T}} and C {\displaystyle C} is symmetric, the solution X {\displaystyle X} will also be symmetric. This symmetry can be exploited so that Y {\displaystyle Y} is found more efficiently in step 3 of the algorithm. == The Hessenberg–Schur algorithm == The Hessenberg–Schur algorithm replaces the decomposition R = U T A U {\displaystyle R=U^{T}AU} in step 1 with the decomposition H = Q T A Q {\displaystyle H=Q^{T}AQ} , where H {\displaystyle H} is an upper-Hessenberg matrix. This leads to a system of the form H Y − Y S T = F {\displaystyle HY-YS^{T}=F} that can be solved using forward substitution. The advantage of this approach is that H = Q T A Q {\displaystyle H=Q^{T}AQ} can be found using Householder reflections at a cost of ( 5 / 3 ) m 3 {\displaystyle (5/3)m^{3}} flops, compared to the 10 m 3 {\displaystyle 10m^{3}} flops required to compute the real Schur decomposition of A {\displaystyle A} . == Software and implementation == The subroutines required for the Hessenberg-Schur variant of the Bartels–Stewart algorithm are implemented in the SLICOT library. These are used in the MATLAB control system toolbox. == Alternative approaches == For large systems, the O ( m 3 + n 3 ) {\displaystyle {\mathcal {O}}(m^{3}+n^{3})} cost of the Bartels–Stewart algorithm can be prohibitive. When A {\displaystyle A} and B {\displaystyle B} are sparse or structured, so that linear solves and matrix vector multiplies involving them are efficient, iterative algorithms can potentially perform better. These include projection-based methods, which use Krylov subspace iterations, methods based on the alternating direction implicit (ADI) iteration, and hybridizations that involve both projection and ADI. Iterative methods can also be used to directly construct low rank approximations to X {\displaystyle X} when solving A X − X B = C {\displaystyle AX-XB=C} .

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  • Library history

    Library history

    Library history is a subdiscipline within library science and library and information science focusing on the history of libraries and their role in societies and cultures. Some see the field as a subset of information history. Library history is an academic discipline and should not be confused with its object of study (history of libraries): the discipline is much younger than the libraries it studies. Library history begins in ancient societies through contemporary issues facing libraries today. Topics include recording mediums, cataloguing systems, scholars, scribes, library supporters and librarians. == Earliest libraries == The earliest records of a library institution as it is presently understood can be dated back to around 5,000 years ago in the Southwest Asian regions of the world. One of the oldest libraries found is that of the ancient library at Ebla (circa 2500 BCE) in present-day Syria. In the 1970s, the excavation at Ebla's library unearthed over 20,000 clay tablets written in cuneiform script. === Library in Mesopotamia === The Assyrian King Assurbanipal created one of the greatest libraries in Nineveh in the seventh century BCE. The collection consisted of over 30,000 tablets written in a variety of languages. The collection was cataloged both by the shape of the tablet and by the subject of the content. The library had separate rooms for the different topics: government, history, law, astronomy, geography, and so on. The tablets also contained myths, hymns, and even jokes. Assurbanipal would send scribes to visit every corner of his kingdom to copy the content of other libraries. His library contained many of the most important literary works of the day, including the epic of Gilgamesh. Assurbanipal's Royal Library also had one of the first library catalogs. Unfortunately, Nineveh was eventually destroyed, and the library was lost in a fire. === Libraries in Ancient Greece === The Greek government was the first to sponsor public libraries. By 500 BCE both Athens and Samos had begun creating libraries for the public, though as most of the population was illiterate these spaces were serving a small, educated portion of the community. Athens developed a city archive at the Metroon in 405 BCE, where documents were stored in sealed jars. These would have saved the documents, but they would have been difficult to consult regularly. In Paros, around the same time, contracts were placed in the temple for safe keeping, and a book curse was placed for extra protection. === Library of Alexandria === The Library at Alexandria, Egypt, was renowned in the third century BCE while kings Ptolemy I Soter and Ptolemy II Philadelphus reigned. The library included a museum, garden, meeting areas and of course reading rooms. The Great Library, as it is known, was one of many in Alexandria. From its inception around the second century BCE, Alexandria was a well-known center for learning. It earned renown as the intellectual capital of the Western world up through the third century CE. The librarians at Alexandria collected, copied, and organized scrolls from across the known world. According to a primary source, every ship that came to Alexandria was required to hand over their books to be copied, and the copies would be returned to the owner, the library keeping the original. The Library of Alexandria was damaged by various disasters over time, including fire, invasion, and earthquake. Scholars believe the collection slowly diminished over time due to theft and efforts to remove it ahead of invading armies. While there are popular stories about how the library was ultimately destroyed, most of these are more myth than fact. === Libraries in Rome === Julius Caesar and his successor Augustus were the first to establish public libraries in ancient Rome, including the library of Apollo on the Palatine Hill. Several emperors followed suit over the next four centuries, including Hadrian, Tiberius, and Vespasian. Roman aristocrats also had personal libraries, which usually contained works in both Greek and Latin. A valuable example of this has been found at Herculaneum near Pompeii. Papyrus manuscripts in Herculaneum's Villa of the Papyri were encased in ash after the eruption of Vesuvius in 79 CE. Modern archaeology is now able to scan these artifacts and discern their contents, including many writings from Philodemus. The average Roman would not have been familiar with books beyond what they might hear read aloud in the forum. Public figures would pay for particular passages to be read aloud to the public from the steps of a public library. === Libraries in the Middle Ages === In the European Middle Ages, libraries began to become more prevalent, despite a widespread reduction in new writing beyond religious themes. Most libraries were initially connected to monasteries or religious institutions. Scriptoriums copied Christian religious texts to share with other religious centers or to be read aloud to their own parishioners. The Holy Roman Emperor Charlemagne (r. 786-814) had a large impact on the advancement of written culture in the Medieval Christian world, acquiring as many written works as he could, and employing many scribes to copy and recirculate vernacular versions of religious works. Most of the text held in small personal libraries was still religious in nature. == Early modern libraries == === Libraries of the Renaissance === During the Renaissance era the merchant middle class grew, and more people found benefits in education. They relied on libraries as a place to study and gain knowledge. Libraries provided a valuable resource, enriching the culture of those who were educated. Universities that had been started in the Middle Ages, founded their own libraries. Books in these libraries could not be borrowed from these libraries and were generally chained to the shelves to prevent theft. As more of the population became literate, new ideas like Humanism and Natural Law spawned an increase personal libraries, although they remained small. Gutenberg's invention of the printing press in 1456 opened the door to the modern era for libraries. == Oldest working libraries == According to the German librarian Michael Knoche, it is not possible to determine which library is the “oldest”: "Precise year dates are a construct, especially in the case of very old libraries. When a collection of books deserves to be called a library depends very much on the point of view of the observer." Various libraries are referred to as the “oldest”: The library founded in the 6th century of the Saint Catherine's Monastery in Sinai is "reputedly the oldest continuously run library in existence today", according to the Library of Congress. Its collection of religious and secular manuscripts is ranging from Bibles, liturgies and prayer books to legal documents such as deeds, court cases and fatwahs (legal opinions). The Al Qarawiyyin Library was founded in 859 by Fatima al-Fihri and is often regarded as the oldest working library in the world. It is in Fez, Morocco and is part of the oldest continually operating university in the world, the University of al-Qarawiyyin. The library houses approximately 4,000 ancient Islamic manuscripts. These manuscripts include 9th century Qurans and the oldest known accounts of the Islamic prophet Muhammed. The Malatestiana Library (Italian: Biblioteca Malatestiana) is a public library in the city of Cesena in northern Italy. Opened in 1454 it is significant for being the first civic library in Europe open to the general public. == Library history reports and writings of the early 19th and 20th century == In the early 19th and 20th century, representative titles were created reporting library history in the United States and the United Kingdom. American titles include Public Libraries in the United States of America, Their History, Condition, and Management (1876), Memorial History of Boston (1881) by Justin Winsor, Public Libraries in America (1894) by William I. Fletcher, and History of the New York Public Library (1923) by Henry M. Lydenberg. British titles include Old English Libraries (1911) by Earnest A. Savage and The Chained Library: A Survey of Four Centuries in the Evolution of the English Library by Burnett Hillman Streeter. In the beginning of the 20th century, library historians began applying scientific research methodologies to examine the library as a social agency. Two works that demonstrate this argument are Geschichte der Bibliotheken (1925) by Alfred Hessel and the Library Quarterly article from 1931, “The Sociological Beginnings of the Library Movement in America” by Arnold Borden. With the establishment of library schools, master's theses and doctoral dissertations represented the shift in serious research regarding libraries and library history. Two published doctoral dissertations that mark this trend are Foundations of the Public Library: The Origins of the American Public Library Movement in Ne

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