AI App How To Use

AI App How To Use — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

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  Color reproduction

  Color reproduction is an aspect of color science concerned with producing light spectra that evoke a desired color, either through additive (light emitting) or subtractive (surface color) models. It converts physical correlates of color perception (CIE 1931 XYZ color space tristimulus values and related quantities) into light spectra that can be experienced by observers. In this way, it is the opposite of colorimetry. It is concerned with the faithful reproduction of a color in one medium, with a color in another, so it is a central concept in color management and relies heavily on color calibration. For example, food packaging must be able to faithfully reproduce the colors of the foods therein in order to appeal to a customer. This involves proper color calibration of at least four devices: Lighting, which must have a high color rendering index and not give a color cast to the object. Camera, which measures the reflected spectrum of the object and converts to a trichromatic color space (e.g. RGB). Screen, which reproduces color so a designer can proof the captured image and make color corrections as necessary. Printer, which reproduces the final color on paper.

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  Memetic algorithm

  In computer science and operations research, a memetic algorithm (MA) is an extension of an evolutionary algorithm (EA) that aims to accelerate the evolutionary search for the optimum. An EA is a metaheuristic that reproduces the basic principles of biological evolution as a computer algorithm in order to solve challenging optimization or planning tasks, at least approximately. An MA uses one or more suitable heuristics or local search techniques to improve the quality of solutions generated by the EA and to speed up the search. The effects on the reliability of finding the global optimum depend on both the use case and the design of the MA. Memetic algorithms represent one of the recent growing areas of research in evolutionary computation. The term MA is now widely used as a synergy of evolutionary or any population-based approach with separate individual learning or local improvement procedures for problem search. Quite often, MAs are also referred to in the literature as Baldwinian evolutionary algorithms, Lamarckian EAs, cultural algorithms, or genetic local search. == Introduction == Inspired by both Darwinian principles of natural evolution and Dawkins' notion of a meme, the term memetic algorithm (MA) was introduced by Pablo Moscato in his technical report in 1989 where he viewed MA as being close to a form of population-based hybrid genetic algorithm (GA) coupled with an individual learning procedure capable of performing local refinements. The metaphorical parallels, on the one hand, to Darwinian evolution and, on the other hand, between memes and domain specific (local search) heuristics are captured within memetic algorithms thus rendering a methodology that balances well between generality and problem specificity. This two-stage nature makes them a special case of dual-phase evolution. The basic idea behind an MA is to combine the advantages of a global search performed by an EA (or another global search method) with the local refinement provided by one or more local search techniques, while avoiding their drawbacks. The main disadvantage of EAs is that, when searching in the vicinity of an optimum, they perform poorly in determining the exact position of that optimum. The downside of local search methods lies simply in the locality of their search relative to the chosen starting point. The combination of these two classes of methods aims to merge global and local search so that the advantages of both approaches can be leveraged. The idea of this approach can be illustrated by the search for the highest mountain in the Alps. A local search method would climb one of the mountains near the starting point, ignoring Mont Blanc as long as the starting point is not in its vicinity. An EA, on the other hand, will likely only find Mont Blanc after examining many other mountains, valleys, and hills, and then it will have difficulty identifying the summit cross. From the perspective of an MA’s global search procedure, however, only the summits of hills and mountains are seen, and its search is limited to finding the best summit. The open question is whether the additional effort required for the local search is worthwhile. This depends not only on the design of the MA but also on the specific application and the local search methods used. In the context of complex optimization, many different instantiations of memetic algorithms have been reported across a wide range of application domains, in general, converging to high-quality solutions more efficiently than their conventional evolutionary counterparts. In general, using the ideas of memetics within a computational framework is called memetic computing or memetic computation (MC). With MC, the traits of universal Darwinism are more appropriately captured. Viewed in this perspective, MA is a more constrained notion of MC. More specifically, MA covers one area of MC, in particular dealing with areas of evolutionary algorithms that marry other deterministic refinement techniques for solving optimization problems. MC extends the notion of memes to cover conceptual entities of knowledge-enhanced procedures or representations. == Theoretical Background == The no-free-lunch theorems of optimization and search state that all optimization strategies are equally effective with respect to the set of all optimization problems. Conversely, this means that one can expect the following: The more efficiently an algorithm solves a problem or class of problems, the less general it is and the more problem-specific knowledge it builds on. This insight leads directly to the recommendation to complement generally applicable metaheuristics with application-specific methods or heuristics, which fits well with the concept of MAs. == The development of MAs == === 1st generation === Pablo Moscato characterized an MA as follows: "Memetic algorithms are a marriage between a population-based global search and the heuristic local search made by each of the individuals. ... The mechanisms to do local search can be to reach a local optimum or to improve (regarding the objective cost function) up to a predetermined level." And he emphasizes "I am not constraining an MA to a genetic representation.". This original definition of MA although encompasses characteristics of cultural evolution (in the form of local refinement) in the search cycle, it may not qualify as a true evolving system according to universal Darwinism, since all the core principles of inheritance/memetic transmission, variation, and selection are missing. This suggests why the term MA stirred up criticisms and controversies among researchers when first introduced. The following pseudo code would correspond to this general definition of an MA: Pseudo code Procedure Memetic Algorithm Initialize: Generate an initial population, evaluate the individuals and assign a quality value to them; while Stopping conditions are not satisfied do Evolve a new population using stochastic search operators. Evaluate all individuals in the population and assign a quality value to them. Select the subset of individuals, Ω i l {\displaystyle \Omega _{il}} , that should undergo the individual improvement procedure. for each individual in Ω i l {\displaystyle \Omega _{il}} do Perform individual learning using meme(s) with frequency or probability of f i l {\displaystyle f_{il}} , with an intensity of t i l {\displaystyle t_{il}} . Proceed with Lamarckian or Baldwinian learning. end for end while Lamarckian learning in this context means to update the chromosome according to the improved solution found by the individual learning step, while Baldwinian learning leaves the chromosome unchanged and uses only the improved fitness. This pseudo code leaves open which steps are based on the fitness of the individuals and which are not. In question are the evolving of the new population and the selection of Ω i l {\displaystyle \Omega _{il}} . Since most MA implementations are based on EAs, the pseudo code of a corresponding representative of the first generation is also given here, following Krasnogor: Pseudo code Procedure Memetic Algorithm Based on an EA Initialization: t = 0 {\displaystyle t=0} ; // Initialization of the generation counter Randomly generate an initial population P ( t ) {\displaystyle P(t)} ; Compute the fitness f ( p ) ∀ p ∈ P ( t ) {\displaystyle f(p)\ \ \forall p\in P(t)} ; while Stopping conditions are not satisfied do Selection: Accordingly to f ( p ) {\displaystyle f(p)} choose a subset of P ( t ) {\displaystyle P(t)} and store it in M ( t ) {\displaystyle M(t)} ; Offspring: Recombine and mutate individuals p ∈ M ( t ) {\displaystyle p\in M(t)} and store them in M ′ ( t ) {\displaystyle M'(t)} ; Learning: Improve p ′ {\displaystyle p'} by local search or heuristic ∀ p ′ ∈ M ′ ( t ) {\displaystyle \forall p'\in M'(t)} ; Evaluation: Compute the fitness f ( p ′ ) ∀ p ′ ∈ M ′ ( t ) {\displaystyle f(p')\ \ \forall p'\in M'(t)} ; if Lamarckian learning then Update chromosome of p ′ {\displaystyle p'} according to improvement ∀ p ′ ∈ M ′ ( t ) {\displaystyle \forall p'\in M'(t)} ; fi New generation: Generate P ( t + 1 ) {\displaystyle P(t+1)} by selecting some individuals from P ( t ) {\displaystyle P(t)} and M ′ ( t ) {\displaystyle M'(t)} ; t = t + 1 {\displaystyle t=t+1} ; // Increment the generation counter end while Return best individual p ∈ P ( t − 1 ) {\displaystyle p\in P(t-1)} as result; There are some alternatives for this MA scheme. For example: All or some of the initial individuals may be improved by the meme(s). The parents may be locally improved instead of the offspring. Instead of all offspring, only a randomly selected or fitness-dependent fraction may undergo local improvement. The latter requires the evaluation of the offspring in M ′ ( t ) {\displaystyle M'(t)} prior to the Learning step. === 2nd generation === Multi-meme, hyper-heuristic and meta-Lamarckian MA are referred to as second generation MA exhibiting the principles of me

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  Random indexing

  Random indexing is a dimensionality reduction method and computational framework for distributional semantics, based on the insight that very-high-dimensional vector space model implementations are impractical, that models need not grow in dimensionality when new items (e.g. new terminology) are encountered, and that a high-dimensional model can be projected into a space of lower dimensionality without compromising L2 distance metrics if the resulting dimensions are chosen appropriately. This is the original point of the random projection approach to dimension reduction first formulated as the Johnson–Lindenstrauss lemma, and locality-sensitive hashing has some of the same starting points. Random indexing, as used in representation of language, originates from the work of Pentti Kanerva on sparse distributed memory, and can be described as an incremental formulation of a random projection. It can be also verified that random indexing is a random projection technique for the construction of Euclidean spaces—i.e. L2 normed vector spaces. In Euclidean spaces, random projections are elucidated using the Johnson–Lindenstrauss lemma. The TopSig technique extends the random indexing model to produce bit vectors for comparison with the Hamming distance similarity function. It is used for improving the performance of information retrieval and document clustering. In a similar line of research, Random Manhattan Integer Indexing (RMII) is proposed for improving the performance of the methods that employ the Manhattan distance between text units. Many random indexing methods primarily generate similarity from co-occurrence of items in a corpus. Reflexive Random Indexing (RRI) generates similarity from co-occurrence and from shared occurrence with other items.

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  Jpred

  Jpred v.4 is the latest version of the JPred Protein Secondary Structure Prediction Server which provides predictions by the JNet algorithm, one of the most accurate methods for secondary structure prediction, that has existed since 1998 in different versions. In addition to protein secondary structure, JPred also makes predictions of solvent accessibility and coiled-coil regions. The JPred service runs up to 134 000 jobs per month and has carried out over 2 million predictions in total for users in 179 countries. == JPred 2 == The static HTML pages of JPred 2 are still available for reference. == JPred 3 == The JPred v3 followed on from previous versions of JPred developed and maintained by James Cuff and Jonathan Barber (see JPred References). This release added new functionality and fixed many bugs. The highlights are: New, friendlier user interface Retrained and optimised version of Jnet (v2) - mean secondary structure prediction accuracy of >81% Batch submission of jobs Better error checking of input sequences/alignments Predictions now (optionally) returned via e-mail Users may provide their own query names for each submission JPred now makes a prediction even when there are no PSI-BLAST hits to the query PS/PDF output now incorporates all the predictions == JPred 4 == The current version of JPred (v4) has the following improvements and updates incorporated: Retrained on the latest UniRef90 and SCOPe/ASTRAL version of Jnet (v2.3.1) - mean secondary structure prediction accuracy of >82%. Upgraded the Web Server to the latest technologies (Bootstrap framework, JavaScript) and updating the web pages – improving the design and usability through implementing responsive technologies. Added RESTful API and mass-submission and results retrieval scripts - resulting in peak throughput above 20,000 predictions per day. Added prediction jobs monitoring tools. Upgraded the results reporting – both, on the web-site, and through the optional email summary reports: improved batch submission, added results summary preview through Jalview results visualization summary in SVG and adding full multiple sequence alignments into the reports. Improved help-pages, incorporating tool-tips, and adding one-page step-by-step tutorials. Sequence residues are categorised or assigned to one of the secondary structure elements, such as alpha-helix, beta-sheet and coiled-coil. Jnet uses two neural networks for its prediction. The first network is fed with a window of 17 residues over each amino acid in the alignment plus a conservation number. It uses a hidden layer of nine nodes and has three output nodes, one for each secondary structure element. The second network is fed with a window of 19 residues (the result of first network) plus the conservation number. It has a hidden layer with nine nodes and has three output nodes.

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  STIT logic

  STIT logic (from seeing to it that) is a family of modal and branching-time logics for reasoning about agency and choice. A typical STIT operator has the form [ i s t i t : φ ] {\displaystyle [i\ {\mathsf {stit}}:\varphi ]} , usually read as "agent i {\displaystyle i} sees to it that φ {\displaystyle \varphi } ", and is interpreted in models where agents choose between alternative possible futures. STIT logics are used in action theory, deontic logic, epistemic logic, and the theory of intelligent agents to formalise notions such as "could have done otherwise", responsibility, joint action, and strategic ability in an indeterministic world. == Etymology == The acronym STIT comes from the English phrase "seeing to it that", introduced in influential work by Nuel Belnap and Michael Perloff on the logical analysis of agentive expressions. In this tradition, "to see to it that φ {\displaystyle \varphi } " is treated as a primitive agency operator, rather than being reduced to ordinary modal necessity. == History == Modern STIT logic arose in the 1980s in the context of branching-time semantics and formal theories of agency. Belnap and Perloff's article "Seeing to it that: A canonical form for agentives" introduced the idea of treating expressions of the form "agent i sees to it that φ" as a primitive modal operator, and analysed such sentences using a branching tree of moments and histories. This approach was further developed in a series of papers on indeterminism and agency and provided the conceptual core for later STIT formalisms. In the 1990s the basic formal systems of STIT logic were worked out. Horty and Belnap's influential paper on the deliberative STIT operator distinguished between a "Chellas" STIT that merely records the result of an agent's present choice and a "deliberative" STIT that requires the agent's choice to make a difference, and connected STIT with issues of action, omission, ability and obligation. Around the same time, Ming Xu proved completeness and decidability results for basic STIT systems, including a single-agent logic with Kripke-style semantics and axiomatizations for multi-agent deliberative STIT, thereby establishing STIT as a well-behaved normal modal framework. This early work was systematised in Belnap, Perloff and Xu's monograph Facing the Future: Agents and Choices in Our Indeterminist World, which presents a general branching-time semantics for individual and group STIT operators, discusses independence-of-agents conditions and articulates the metaphysical picture of an indeterministic "tree" of moments. At roughly the same time, Horty's book Agency and Deontic Logic developed deontic STIT logics in which obligations are tied to agents' available choices rather than to static states of affairs, and used the resulting systems to analyse "ought implies can", contrary-to-duty obligations and deontic paradoxes. These works helped to position STIT at the intersection of action theory, temporal logic and deontic logic. From the late 1990s and 2000s onward, STIT logics were combined with epistemic, temporal and strategic modalities. Broersen introduced complete STIT logics for knowledge and action and deontic-epistemic STIT systems that distinguish different modes of mens rea, with applications to responsibility and the specification of multi-agent systems. Work on group and coalitional agency investigated axiomatisations and complexity results for group STIT logics, and related STIT-based analyses of agency to coalition logic and alternating-time temporal logic (ATL) by exhibiting formal embeddings between the frameworks. Explicit temporal operators were added to STIT in so-called temporal STIT logics. Lorini proposed a temporal STIT with "next" and "until" operators along histories and showed how it can be applied to normative reasoning about ongoing behaviour and commitments. Ciuni and Lorini compared different semantics for temporal STIT, clarifying the relationships between branching-time, game-based and epistemic approaches, while Boudou and Lorini gave a semantics for temporal STIT based on concurrent game structures, thus strengthening links with standard models of multi-agent interaction used for ATL and strategy logic. In parallel, complexity-theoretic work by Balbiani, Herzig and Troquard and by Schwarzentruber and co-authors investigated the satisfiability and model-checking problems for various STIT fragments, showing for instance that many expressive group STIT logics are undecidable or of high computational complexity. In the 2010s, STIT ideas were combined with justification logic, imagination operators and refined deontic notions. Justification STIT logics, developed by Olkhovikov and others, merge explicit justifications with STIT-style agency so that producing a proof can itself be treated as an action that brings about knowledge, and they come with completeness and decidability results. Olkhovikov and Wansing introduced STIT imagination logics, together with axiomatic systems and tableau calculi, to model acts of voluntary imagining and their role in doxastic control. Other authors have proposed STIT-based logics of responsibility, blameworthiness and intentionality for use in philosophical and AI settings. Xu's survey article "Combinations of STIT with Ought and Know" (2015) reviews many of these developments and emphasises the interplay between deontic and epistemic STIT logics. Current research on STIT focuses on proof theory, automated reasoning and richer expressive resources. Lyon and van Berkel, building on earlier work on labelled calculi for STIT, have developed cut-free sequent systems and proof-search algorithms that yield syntactic decision procedures for a range of deontic and non-deontic multi-agent STIT logics and support applications such as duty checking and compliance checking in autonomous systems. Sawasaki has proposed first-order cstit-based STIT logics that can distinguish de re and de dicto readings of agency statements and has proved strong completeness results for Hilbert systems over finite models, moving the STIT programme beyond the purely propositional level. Further work investigates interpreted-system and computationally grounded semantics for STIT and its extensions in order to model the behaviour of autonomous agents in multi-agent settings, and proposes STIT-based semantics for epistemic notions based on patterns of information disclosure in interactive systems. == Branching-time semantics == STIT logics are usually interpreted over branching-time models. A standard STIT frame consists of: a non-empty set of moments T {\displaystyle T} , partially ordered by < {\displaystyle <} so that ( T , < ) {\displaystyle (T,<)} forms a tree (every pair of moments with a common predecessor has a greatest lower bound); a set of histories, each history being a maximal linearly ordered subset of T {\displaystyle T} ; a non-empty set of agents A g {\displaystyle Ag} ; for each agent i ∈ A g {\displaystyle i\in Ag} and moment m {\displaystyle m} , a choice function c h o i c e i m {\displaystyle {\mathsf {choice}}_{i}^{m}} that partitions the set of histories passing through m {\displaystyle m} into choice cells. The idea is that a moment represents a time at which choices are made, and histories represent complete possible future courses of events. At each moment, each agent's choice corresponds to selecting one of the available cells of histories determined by their choice function. Formulas are evaluated at pairs ( m , h ) {\displaystyle (m,h)} of a moment and a history through that moment (sometimes written m / h {\displaystyle m/h} ). A valuation assigns truth-values to atomic propositions at such indices; Boolean connectives are interpreted pointwise as in Kripke-style modal logic. == Chellas and deliberative STIT operators == Several STIT operators have been distinguished in the literature. A common approach uses two closely related operators, often called Chellas STIT and deliberative STIT. Let H m {\displaystyle H_{m}} be the set of histories passing through a moment m {\displaystyle m} , and write H m {\displaystyle H_{m}} ⟦ φ ⟧ m = { h ∈ H m ∣ M , m / h ⊨ φ } {\displaystyle {\text{⟦}}\varphi {\text{⟧}}_{m}=\{h\in H_{m}\mid M,m/h\models \varphi \}} for the set of histories at m {\displaystyle m} where φ {\displaystyle \varphi } holds. The Chellas STIT operator, often written [ i c s t i t : φ ] {\displaystyle [i\ {\mathsf {cstit}}:\varphi ]} , is given by M , m / h ⊨ [ i c s t i t : φ ] iff c h o i c e i m ( h ) ⊆ ⟦ φ ⟧ m . {\displaystyle M,m/h\models [i\ {\mathsf {cstit}}:\varphi ]\quad {\text{iff}}\quad {\mathsf {choice}}_{i}^{m}(h)\subseteq {\text{⟦}}\varphi {\text{⟧}}_{m}.} Intuitively, agent i {\displaystyle i} sees to it that φ {\displaystyle \varphi } if φ {\displaystyle \varphi } holds at all histories compatible with their present choice. The deliberative STIT operator, [ i d s t i t : φ ] {\displaystyle [i\ {\mathsf {dstit}}:\varphi ]} , adds

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  Stochastic gradient descent

  Stochastic gradient descent (often abbreviated SGD) is an iterative method for optimizing an objective function with suitable smoothness properties (e.g. differentiable or subdifferentiable). It can be regarded as a stochastic approximation of gradient descent optimization, since it replaces the actual gradient (calculated from the entire data set) by an estimate thereof (calculated from a randomly selected subset of the data). Especially in high-dimensional optimization problems this reduces the very high computational burden, achieving faster iterations in exchange for a lower convergence rate. The basic idea behind stochastic approximation can be traced back to the Robbins–Monro algorithm of the 1950s. Today, stochastic gradient descent has become an important optimization method in machine learning. == Background == Both statistical estimation and machine learning consider the problem of minimizing an objective function that has the form of a sum: Q ( w ) = 1 n ∑ i = 1 n Q i ( w ) , {\displaystyle Q(w)={\frac {1}{n}}\sum _{i=1}^{n}Q_{i}(w),} where the parameter w {\displaystyle w} that minimizes Q ( w ) {\displaystyle Q(w)} is to be estimated. Each summand function Q i {\displaystyle Q_{i}} is typically associated with the i {\displaystyle i} -th observation in the data set (used for training). In classical statistics, sum-minimization problems arise in least squares and in maximum-likelihood estimation (for independent observations). The general class of estimators that arise as minimizers of sums are called M-estimators. However, in statistics, it has been long recognized that requiring even local minimization is too restrictive for some problems of maximum-likelihood estimation. Therefore, contemporary statistical theorists often consider stationary points of the likelihood function (or zeros of its derivative, the score function, and other estimating equations). The sum-minimization problem also arises for empirical risk minimization. There, Q i ( w ) {\displaystyle Q_{i}(w)} is the value of the loss function at i {\displaystyle i} -th example, and Q ( w ) {\displaystyle Q(w)} is the empirical risk. When used to minimize the above function, a standard (or "batch") gradient descent method would perform the following iterations: w := w − η ∇ Q ( w ) = w − η n ∑ i = 1 n ∇ Q i ( w ) . {\displaystyle w:=w-\eta \,\nabla Q(w)=w-{\frac {\eta }{n}}\sum _{i=1}^{n}\nabla Q_{i}(w).} The step size is denoted by η {\displaystyle \eta } (sometimes called the learning rate in machine learning) and here " := {\displaystyle :=} " denotes the update of a variable in the algorithm. In many cases, the summand functions have a simple form that enables inexpensive evaluations of the sum-function and the sum gradient. For example, in statistics, one-parameter exponential families allow economical function-evaluations and gradient-evaluations. However, in other cases, evaluating the sum-gradient may require expensive evaluations of the gradients from all summand functions. When the training set is enormous and no simple formulas exist, evaluating the sums of gradients becomes very expensive, because evaluating the gradient requires evaluating all the summand functions' gradients. To economize on the computational cost at every iteration, stochastic gradient descent samples a subset of summand functions at every step. This is very effective in the case of large-scale machine learning problems. == Iterative method == In stochastic (or "on-line") gradient descent, the true gradient of Q ( w ) {\displaystyle Q(w)} is approximated by a gradient at a single sample: w := w − η ∇ Q i ( w ) . {\displaystyle w:=w-\eta \,\nabla Q_{i}(w).} As the algorithm sweeps through the training set, it performs the above update for each training sample. Several passes can be made over the training set until the algorithm converges. If this is done, the data can be shuffled for each pass to prevent cycles. Typical implementations may use an adaptive learning rate so that the algorithm converges. In pseudocode, stochastic gradient descent can be presented as : A compromise between computing the true gradient and the gradient at a single sample is to compute the gradient against more than one training sample (called a "mini-batch") at each step. This can perform significantly better than "true" stochastic gradient descent described, because the code can make use of vectorization libraries rather than computing each step separately as was first shown in where it was called "the bunch-mode back-propagation algorithm". It may also result in smoother convergence, as the gradient computed at each step is averaged over more training samples. The convergence of stochastic gradient descent has been analyzed using the theories of convex minimization and of stochastic approximation. Briefly, when the learning rates η {\displaystyle \eta } decrease with an appropriate rate, and subject to relatively mild assumptions, stochastic gradient descent converges almost surely to a global minimum when the objective function is convex or pseudoconvex, and otherwise converges almost surely to a local minimum. This is in fact a consequence of the Robbins–Siegmund theorem. == Linear regression == Suppose we want to fit a straight line y ^ = w 1 + w 2 x {\displaystyle {\hat {y}}=w_{1}+w_{2}x} to a training set with observations ( ( x 1 , y 1 ) , ( x 2 , y 2 ) … , ( x n , y n ) ) {\displaystyle ((x_{1},y_{1}),(x_{2},y_{2})\ldots ,(x_{n},y_{n}))} and corresponding estimated responses ( y ^ 1 , y ^ 2 , … , y ^ n ) {\displaystyle ({\hat {y}}_{1},{\hat {y}}_{2},\ldots ,{\hat {y}}_{n})} using least squares. The objective function to be minimized is Q ( w ) = ∑ i = 1 n Q i ( w ) = ∑ i = 1 n ( y ^ i − y i ) 2 = ∑ i = 1 n ( w 1 + w 2 x i − y i ) 2 . {\displaystyle Q(w)=\sum _{i=1}^{n}Q_{i}(w)=\sum _{i=1}^{n}\left({\hat {y}}_{i}-y_{i}\right)^{2}=\sum _{i=1}^{n}\left(w_{1}+w_{2}x_{i}-y_{i}\right)^{2}.} The last line in the above pseudocode for this specific problem will become: [ w 1 w 2 ] ← [ w 1 w 2 ] − η [ ∂ ∂ w 1 ( w 1 + w 2 x i − y i ) 2 ∂ ∂ w 2 ( w 1 + w 2 x i − y i ) 2 ] = [ w 1 w 2 ] − η [ 2 ( w 1 + w 2 x i − y i ) 2 x i ( w 1 + w 2 x i − y i ) ] . {\displaystyle {\begin{bmatrix}w_{1}\\w_{2}\end{bmatrix}}\leftarrow {\begin{bmatrix}w_{1}\\w_{2}\end{bmatrix}}-\eta {\begin{bmatrix}{\frac {\partial }{\partial w_{1}}}(w_{1}+w_{2}x_{i}-y_{i})^{2}\\{\frac {\partial }{\partial w_{2}}}(w_{1}+w_{2}x_{i}-y_{i})^{2}\end{bmatrix}}={\begin{bmatrix}w_{1}\\w_{2}\end{bmatrix}}-\eta {\begin{bmatrix}2(w_{1}+w_{2}x_{i}-y_{i})\\2x_{i}(w_{1}+w_{2}x_{i}-y_{i})\end{bmatrix}}.} Note that in each iteration or update step, the gradient is only evaluated at a single x i {\displaystyle x_{i}} . This is the key difference between stochastic gradient descent and batched gradient descent. In general, given a linear regression y ^ = ∑ k ∈ 1 : m w k x k {\displaystyle {\hat {y}}=\sum _{k\in 1:m}w_{k}x_{k}} problem, stochastic gradient descent behaves differently when m < n {\displaystyle m

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  Latent space

  A latent space, also known as a latent feature space or embedding space, is an embedding of a set of items within a manifold in which items resembling each other are positioned closer to one another. Position within the latent space can be viewed as being defined by a set of latent variables that emerge from the resemblances between the objects. In most cases, the dimensionality of the latent space is chosen to be lower than the dimensionality of the feature space from which the data points are drawn, making the construction of a latent space an example of dimensionality reduction, which can also be viewed as a form of data compression. Latent spaces are usually fit via machine learning, and they can then be used as feature spaces in machine learning models, including classifiers and other supervised predictors. The interpretation of latent spaces in machine learning models is an ongoing area of research, but achieving clear interpretations remains challenging. The black-box nature of these models often makes the latent space unintuitive, while its high-dimensional, complex, and nonlinear characteristics further complicate the task of understanding it. Analysis of the latent space geometry of diffusion models reveals a fractal structure of phase transitions in the latent space, characterized by abrupt changes in the Fisher information metric. Some visualization techniques have been developed to connect the latent space to the visual world, but there is often not a direct connection between the latent space interpretation and the model itself. Such techniques include t-distributed stochastic neighbor embedding (t-SNE), where the latent space is mapped to two dimensions for visualization. Latent space distances lack physical units, so the interpretation of these distances may depend on the application. == Embedding models == Several embedding models have been developed to perform this transformation to create latent space embeddings given a set of data items and a similarity function. These models learn the embeddings by leveraging statistical techniques and machine learning algorithms. Here are some commonly used embedding models: Word2Vec: Word2Vec is a popular embedding model used in natural language processing (NLP). It learns word embeddings by training a neural network on a large corpus of text. Word2Vec captures semantic and syntactic relationships between words, allowing for meaningful computations like word analogies. GloVe: GloVe (Global Vectors for Word Representation) is another widely used embedding model for NLP. It combines global statistical information from a corpus with local context information to learn word embeddings. GloVe embeddings are known for capturing both semantic and relational similarities between words. Siamese Networks: Siamese networks are a type of neural network architecture commonly used for similarity-based embedding. They consist of two identical subnetworks that process two input samples and produce their respective embeddings. Siamese networks are often used for tasks like image similarity, recommendation systems, and face recognition. Variational Autoencoders (VAEs): VAEs are generative models that simultaneously learn to encode and decode data. The latent space in VAEs acts as an embedding space. By training VAEs on high-dimensional data, such as images or audio, the model learns to encode the data into a compact latent representation. VAEs are known for their ability to generate new data samples from the learned latent space. == Multimodality == Multimodality refers to the integration and analysis of multiple modes or types of data within a single model or framework. Embedding multimodal data involves capturing relationships and interactions between different data types, such as images, text, audio, and structured data. Multimodal embedding models aim to learn joint representations that fuse information from multiple modalities, allowing for cross-modal analysis and tasks. These models enable applications like image captioning, visual question answering, and multimodal sentiment analysis. To embed multimodal data, specialized architectures such as deep multimodal networks or multimodal transformers are employed. These architectures combine different types of neural network modules to process and integrate information from various modalities. The resulting embeddings capture the complex relationships between different data types, facilitating multimodal analysis and understanding. == Applications == Embedding latent space and multimodal embedding models have found numerous applications across various domains: Information retrieval: Embedding techniques enable efficient similarity search and recommendation systems by representing data points in a compact space. Natural language processing: Word embeddings have revolutionized NLP tasks like sentiment analysis, machine translation, and document classification. Computer vision: Image and video embeddings enable tasks like object recognition, image retrieval, and video summarization. Recommendation systems: Embeddings help capture user preferences and item characteristics, enabling personalized recommendations. Healthcare: Embedding techniques have been applied to electronic health records, medical imaging, and genomic data for disease prediction, diagnosis, and treatment. Social systems: Embedding techniques can be used to learn latent representations of social systems such as internal migration systems, academic citation networks, and world trade networks.

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  Generalized blockmodeling of valued networks

  Generalized blockmodeling of valued networks is an approach of the generalized blockmodeling, dealing with valued networks (e.g., non-binary). While the generalized blockmodeling signifies a "formal and integrated approach for the study of the underlying functional anatomies of virtually any set of relational data", it is in principle used for binary networks. This is evident from the set of ideal blocks, which are used to interpret blockmodels, that are binary, based on the characteristic link patterns. Because of this, such templates are "not readily comparable with valued empirical blocks". To allow generalized blockmodeling of valued directional (one-mode) networks (e.g. allowing the direct comparisons of empirical valued blocks with ideal binary blocks), a non–parametric approach is used. With this, "an optional parameter determines the prominence of valued ties as a minimum percentile deviation between observed and expected flows". Such two–sided application of parameter then introduces "the possibility of non–determined ties, i.e. valued relations that are deemed neither prominent (1) nor non–prominent (0)." Resulted occurrences of links then motivate the modification of the calculation of inconsistencies between empirical and ideal blocks. At the same time, such links also give a possibility to measure the interpretational certainty, which is specific to each ideal block. Such maximum two–sided deviation threshold, holding the aggregate uncertainty score at zero or near–zero levels, is then proposed as "a measure of interpretational certainty for valued blockmodels, in effect transforming the optional parameter into an outgoing state". Problem with blockmodeling is the standard set of ideal block, as they are all specified using binary link (tie) patters; this results in "a non–trivial exercise to match and count inconsistencies between such ideal binary ties and empirical valued ties". One approach to solve this is by using dichotomization to transform the network into a binary version. The other two approaches were first proposed by Aleš Žiberna in 2007 by introducing valued (generalized) blockmodeling and also homogeneity blockmodeling. The basic idea of the latter is "that the inconsistency of an empirical block with its ideal block can be measured by within block variability of appropriate values". The newly–formed ideal blocks, which are appropriate for blockmodeling of valued networks, are then presented together with the definitions of their block inconsistencies. Two other approaches were later suggested by Carl Nordlund in 2019: deviational approach and correlation-based generalized approach. Both Nordlund's approaches are based on the idea, that valued networks can be compared with the ideal block without values. With this approach, more information is retained for analysis, which also means, that there are fewer partitions having identical values of the criterion function. This means, that the generalized blockmodeling of valued networks measures the inconsistencies more precisely. Usually, only one optimal partition is found in this approach, especially when it is used by homogeneity blockmodeling. Contrary, while using binary blockmodeling on the same sample, usually more than one optimal partition had occurred on several occasions.

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  Anthem medical data breach

  The Anthem medical data breach was a medical data breach of information held by Elevance Health, known at that time as Anthem Inc. On February 4, 2015, Anthem, Inc. disclosed that criminal hackers had broken into its servers and had potentially stolen over 37.5 million records that contain personally identifiable information from its servers. On February 24, 2015 Anthem raised the number to 78.8 million people whose personal information had been affected. According to Anthem, Inc., the data breach extended into multiple brands Anthem, Inc. uses to market its healthcare plans, including, Anthem Blue Cross, Anthem Blue Cross and Blue Shield, Blue Cross and Blue Shield of Georgia, Empire Blue Cross and Blue Shield, Amerigroup, Caremore, and UniCare. Healthlink says that it was also a victim. Anthem says users' medical information and financial data were not compromised. Anthem has offered free credit monitoring in the wake of the breach. Michael Daniel, chief adviser on cybersecurity for President Barack Obama, said he would be changing his own password. According to The New York Times, about 80 million company records were hacked, and there is a fear that the stolen data will be used for identity theft. The compromised information contained names, birthdays, medical IDs, social security numbers, street addresses, e-mail addresses and employment information, including income data. == Theft of the data == The data was stolen over a period of weeks the month before the data breach was discovered. Because no medical information was compromised, Anthem was not required by law to encrypt the data. However, Anthem faced several civil class-action lawsuits, which were settled in 2017 at a cost of $115 million. Anthem did not admit any wrongdoing in the settlement. Data from the attack is expected to be sold on the black market. == Impact == Persons whose data was stolen could have resulting problems about identity theft for the rest of their lives. Anthem had a US$100 million insurance policy for cyber problems from American International Group. One report suggested that all of this money could be consumed by the process of notifying customers of the breach. == Responses == Anthem hired Mandiant, a cybersecurity firm, to review their security systems and advised people whose data was stolen to monitor their accounts and remain vigilant. The theft of the data raised fears generally about the theft of medical information. A writer from Harvard Law School suggested that this data breach might spark reform of security practices and government data safety regulation. An investigation conducted by several state insurance commissioners blames the breach on an attacker whose identity was withheld, and claims that the breach was likely ordered by a foreign government whose name was withheld. It also concluded that Anthem had taken reasonable measures to protect its data before the breach and that its remediation plan was effective at shutting down the breach once it was discovered. It also marks the starting date of the breach as February 18, 2014. The lead investigator was the Indiana Department of Insurance (DOI) -- Anthem's principal regulator, because Anthem is headquartered in Indiana. The Indiana DOI hired independent auditors to conduct a security assessment at Anthem, which concluded, "While deficiencies within Anthem’s cybersecurity posture were noted by the Examination Team, these deficiencies were not, in our experience, uncommon to companies comparable to Anthem in size and scope. While the pre-breach deficiencies impacted Anthem’s ability to reduce the likelihood of and quickly detect the Data Breach, the controls implemented subsequent to the Data Breach should improve Anthem’s ability to detect future breaches and enable Anthem to respond more effectively to a future attack than was the case in this instance." Federal regulators also conducted an investigation of the Anthem data breach, resulting in a $16 million settlement between Anthem and the Department of Health and Human Services (HHS) -- by far the largest HHS data breach settlement. An HHS Director overseeing the investigation said, "The largest health data breach in U.S. history fully merits the largest HIPAA settlement in history. Unfortunately, Anthem failed to implement appropriate measures for detecting hackers who had gained access to their system to harvest passwords and steal people's private information." The HHS settlement also required Anthem to perform a risk assessment and correct any identified deficiencies in its cybersecurity, with HHS oversight of Anthem's progress. Approximately 100 private class action lawsuits were filed against Anthem over the data breach and consolidated in California federal court, in front of Judge Koh, a respected authority in data breach litigation. After contested briefing over who should lead the litigation efforts, Judge Koh appoints Eve Cervantez of Altshuler Berzon and Andy Friedman of Cohen Milstein as co-lead counsel, and appointed Eric Gibbs of Gibbs Law Group and Michael Sobel of Lieff Cabraser to head a Plaintiffs' Steering Committee. In 2017, Anthem agreed to settle the litigation for $115 million, the largest ever data breach settlement at the time. The attorneys requested $38 million in fees for their work on the case, but Judge Koh slashed the fee request, finding that only $31 million in fees were merited.

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  Loss function

  In mathematical optimization and decision theory, a loss function or cost function (sometimes also called an error function) is a function that maps an event or values of one or more variables onto a real number intuitively representing some "cost" associated with the event. An optimization problem seeks to minimize a loss function. An objective function is either a loss function or its opposite (in specific domains, variously called a reward function, a profit function, a utility function, a fitness function, etc.), in which case it is to be maximized. The loss function could include terms from several levels of the hierarchy. In statistics, typically a loss function is used for parameter estimation, and the event in question is some function of the difference between estimated and true values for an instance of data. The concept, as old as Laplace, was reintroduced in statistics by Abraham Wald in the middle of the 20th century. In the context of economics, for example, this is usually economic cost or regret. In classification, it is the penalty for an incorrect classification of an example. In actuarial science, it is used in an insurance context to model benefits paid over premiums, particularly since the works of Harald Cramér in the 1920s. In optimal control, the loss is the penalty for failing to achieve a desired value. In financial risk management, the function is mapped to a monetary loss. == Examples == === Regret === Leonard J. Savage argued that using non-Bayesian methods such as minimax, the loss function should be based on the idea of regret, i.e., the loss associated with a decision should be the difference between the consequences of the best decision that could have been made under circumstances will be known and the decision that was in fact taken before they were known. === Quadratic loss function === The use of a quadratic loss function is common, for example when using least squares techniques. It is often more mathematically tractable than other loss functions because of the properties of variances, as well as being symmetric: an error above the target causes the same loss as the same magnitude of error below the target. If the target is t {\displaystyle t} , then a quadratic loss function is λ ( x ) = C ( t − x ) 2 {\displaystyle \lambda (x)=C(t-x)^{2}\;} for some constant C {\displaystyle C} ; the value of the constant makes no difference to a decision, and can be ignored by setting it equal to 1. This is also known as the squared error loss (SEL). Many common statistics, including t-tests, regression models, design of experiments, and much else, use least squares methods applied using linear regression theory, which is based on the quadratic loss function. The quadratic loss function is also used in linear-quadratic optimal control problems. In these problems, even in the absence of uncertainty, it may not be possible to achieve the desired values of all target variables. Often loss is expressed as a quadratic form in the deviations of the variables of interest from their desired values; this approach is tractable because it results in linear first-order conditions. In the context of stochastic control, the expected value of the quadratic form is used. The quadratic loss assigns more importance to outliers than to the true data due to its square nature, so alternatives like the Huber, log-cosh and SMAE losses are used when the data has many large outliers. === 0-1 loss function === In statistics and decision theory, a frequently used loss function is the 0-1 loss function L ( y ^ , y ) = { 0 if y = y ^ 1 if y ≠ y ^ {\displaystyle L({\hat {y}},y)={\begin{cases}0&{\text{if }}y={\hat {y}}\\1&{\text{if }}y\neq {\hat {y}}\end{cases}}} In information theory, this loss function is known as Hamming distortion. == Constructing loss and objective functions == In many applications, objective functions, including loss functions as a particular case, are determined by the problem formulation. In other situations, the decision maker’s preference must be elicited and represented by a scalar-valued function (called also utility function) in a form suitable for optimization — the problem that Ragnar Frisch has highlighted in his Nobel Prize lecture. The existing methods for constructing objective functions are collected in the proceedings of two dedicated conferences. In particular, Andranik Tangian showed that the most usable objective functions — quadratic and additive — are determined by a few indifference points. He used this property in the models for constructing these objective functions from either ordinal or cardinal data that were elicited through computer-assisted interviews with decision makers. Among other things, he constructed objective functions to optimally distribute budgets for 16 Westfalian universities and the European subsidies for equalizing unemployment rates among 271 German regions. == Expected loss == In some contexts, the value of the loss function itself is a random quantity because it depends on the outcome of a random variable X {\displaystyle X} . === Statistics === Both frequentist and Bayesian statistical theory involve making a decision based on the expected value of the loss function; however, this quantity is defined differently under the two paradigms. ==== Frequentist expected loss ==== We first define the expected loss in the frequentist context. It is obtained by taking the expected value with respect to the probability distribution, P θ {\displaystyle P_{\theta }} , of the observed data, X {\displaystyle X} . This is also referred to as the risk function of the decision rule δ {\displaystyle \delta } and the parameter θ {\displaystyle \theta } . Here the decision rule depends on the outcome of X {\displaystyle X} . The risk function is given by: R ( θ , δ ) = E θ ⁡ L ( θ , δ ( X ) ) = ∫ X L ( θ , δ ( x ) ) d P θ ( x ) . {\displaystyle R(\theta ,\delta )=\operatorname {E} _{\theta }L{\big (}\theta ,\delta (X){\big )}=\int _{X}L{\big (}\theta ,\delta (x){\big )}\,\mathrm {d} P_{\theta }(x).} Here, θ {\displaystyle \theta } is a fixed but possibly unknown state of nature, X {\displaystyle X} is a vector of observations stochastically drawn from a population, E θ {\displaystyle \operatorname {E} _{\theta }} is the expectation over all population values of X {\displaystyle X} , d P θ {\displaystyle \mathrm {d} P_{\theta }} is a probability measure over the event space of X {\displaystyle X} (parametrized by θ {\displaystyle \theta } ) and the integral is evaluated over the entire support of X {\displaystyle X} . ==== Bayes Risk ==== In a Bayesian approach, the expectation is calculated using the prior distribution π ∗ {\displaystyle \pi ^{}} of the parameter θ {\displaystyle \theta } : ρ ( π ∗ , a ) = ∫ Θ ∫ X L ( θ , a ( x ) ) d P ( x | θ ) d π ∗ ( θ ) = ∫ X ∫ Θ L ( θ , a ( x ) ) d π ∗ ( θ | x ) d M ( x ) {\displaystyle \rho (\pi ^{},a)=\int _{\Theta }\int _{\mathbf {X}}L(\theta ,a({\mathbf {x}}))\,\mathrm {d} P({\mathbf {x}}\vert \theta )\,\mathrm {d} \pi ^{}(\theta )=\int _{\mathbf {X}}\int _{\Theta }L(\theta ,a({\mathbf {x}}))\,\mathrm {d} \pi ^{}(\theta \vert {\mathbf {x}})\,\mathrm {d} M({\mathbf {x}})} where M ( x ) {\displaystyle M(\mathbf {x} )} is known as the predictive likelihood wherein θ {\displaystyle \theta } has been "integrated out," π ∗ ( θ | x ) {\displaystyle \pi ^{}(\theta |\mathbf {x} )} is the posterior distribution, and the order of integration has been changed. One then should choose the action a ∗ {\displaystyle a^{}} which minimises this expected loss, which is referred to as Bayes Risk. In the latter equation, the integrand inside d x {\displaystyle \mathrm {d} x} is known as the Posterior Risk, and minimising it with respect to decision a {\displaystyle a} also minimizes the overall Bayes Risk. This optimal decision, a ∗ {\displaystyle a^{}} is known as the Bayes (decision) Rule - it minimises the average loss over all possible states of nature θ {\displaystyle \theta } , over all possible (probability-weighted) data outcomes. One advantage of the Bayesian approach is to that one need only choose the optimal action under the actual observed data to obtain a uniformly optimal one, whereas choosing the actual frequentist optimal decision rule as a function of all possible observations, is a much more difficult problem. Of equal importance though, the Bayes Rule reflects consideration of loss outcomes under different states of nature, θ {\displaystyle \theta } . ==== Examples in statistics ==== For a scalar parameter θ {\displaystyle \theta } , a decision function whose output θ ^ {\displaystyle {\hat {\theta }}} is an estimate of θ {\displaystyle \theta } , and a quadratic loss function (squared error loss) L ( θ , θ ^ ) = ( θ − θ ^ ) 2 , {\displaystyle L(\theta ,{\hat {\theta }})=(\theta -{\hat {\theta }})^{2},} the risk function becomes the mean squared error of the estimate, R ( θ , θ ^ ) = E θ ⁡ [ ( θ − θ ^ ) 2 ] . {\displaystyle R(\theta ,{\hat {\thet

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  VIGRA

  VIGRA is the abbreviation for "Vision with Generic Algorithms". It is a free open-source computer vision library which focuses on customizable algorithms and data structures. VIGRA component can be easily adapted to specific needs of target application without compromising execution speed, by using template techniques similar to those in the C++ Standard Template Library. == Features == VIGRA is cross-platform, with working builds on Microsoft Windows, Mac OS X, Linux, and OpenBSD. Since version 1.7.1, VIGRA provides Python bindings based on numpy framework. == History == VIGRA was originally designed and implemented by scientists at University of Hamburg faculty of computer science; its core maintainers are now working at Heidelberg Collaboratory for Image Processing (HCI) University of Heidelberg. In the meantime, many developers have contributed to the project. == Application == CellCognition and ilastik uses VIGRA computer vision library. OpenOffice.org uses VIGRA as part of its headless software rendering backend; LibreOffice does so until version 5.2.

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  Junction tree algorithm

  The junction tree algorithm (also known as 'Clique Tree') is a method used in machine learning to extract marginalization in general graphs. In essence, it entails performing belief propagation on a modified graph called a junction tree. The graph is called a tree because it branches into different sections of data; nodes of variables are the branches. The basic premise is to eliminate cycles by clustering them into single nodes. Multiple extensive classes of queries can be compiled at the same time into larger structures of data. There are different algorithms to meet specific needs and for what needs to be calculated. Inference algorithms gather new developments in the data and calculate it based on the new information provided. == Junction tree algorithm == === Hugin algorithm === If the graph is directed then moralize it to make it un-directed. Introduce the evidence. Triangulate the graph to make it chordal. Construct a junction tree from the triangulated graph (we will call the vertices of the junction tree "supernodes"). Propagate the probabilities along the junction tree (via belief propagation) Note that this last step is inefficient for graphs of large treewidth. Computing the messages to pass between supernodes involves doing exact marginalization over the variables in both supernodes. Performing this algorithm for a graph with treewidth k will thus have at least one computation which takes time exponential in k. It is a message passing algorithm. The Hugin algorithm takes fewer computations to find a solution compared to Shafer-Shenoy. === Shafer-Shenoy algorithm === Computed recursively Multiple recursions of the Shafer-Shenoy algorithm results in Hugin algorithm Found by the message passing equation Separator potentials are not stored The Shafer-Shenoy algorithm is the sum product of a junction tree. It is used because it runs programs and queries more efficiently than the Hugin algorithm. The algorithm makes calculations for conditionals for belief functions possible. Joint distributions are needed to make local computations happen. === Underlying theory === The first step concerns only Bayesian networks, and is a procedure to turn a directed graph into an undirected one. We do this because it allows for the universal applicability of the algorithm, regardless of direction. The second step is setting variables to their observed value. This is usually needed when we want to calculate conditional probabilities, so we fix the value of the random variables we condition on. Those variables are also said to be clamped to their particular value. The third step is to ensure that graphs are made chordal if they aren't already chordal. This is the first essential step of the algorithm. It makes use of the following theorem: Theorem: For an undirected graph, G, the following properties are equivalent: Graph G is triangulated. The clique graph of G has a junction tree. There is an elimination ordering for G that does not lead to any added edges. Thus, by triangulating a graph, we make sure that the corresponding junction tree exists. A usual way to do this, is to decide an elimination order for its nodes, and then run the Variable elimination algorithm. The variable elimination algorithm states that the algorithm must be run each time there is a different query. This will result to adding more edges to the initial graph, in such a way that the output will be a chordal graph. All chordal graphs have a junction tree. The next step is to construct the junction tree. To do so, we use the graph from the previous step, and form its corresponding clique graph. Now the next theorem gives us a way to find a junction tree: Theorem: Given a triangulated graph, weight the edges of the clique graph by their cardinality, |A∩B|, of the intersection of the adjacent cliques A and B. Then any maximum-weight spanning tree of the clique graph is a junction tree. So, to construct a junction tree we just have to extract a maximum weight spanning tree out of the clique graph. This can be efficiently done by, for example, modifying Kruskal's algorithm. The last step is to apply belief propagation to the obtained junction tree. Usage: A junction tree graph is used to visualize the probabilities of the problem. The tree can become a binary tree to form the actual building of the tree. A specific use could be found in auto encoders, which combine the graph and a passing network on a large scale automatically. === Inference Algorithms === Loopy belief propagation: A different method of interpreting complex graphs. The loopy belief propagation is used when an approximate solution is needed instead of the exact solution. It is an approximate inference. Cutset conditioning: Used with smaller sets of variables. Cutset conditioning allows for simpler graphs that are easier to read but are not exact.

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  Automated medical scribe

  Automated medical scribes (also called artificial intelligence scribes, AI scribes, digital scribes, virtual scribes, ambient AI scribes, AI documentation assistants, and digital/virtual/smart clinical assistants) are tools for transcribing medical speech, such as patient consultations and dictated medical notes. Many also produce summaries of consultations. Automated medical scribes based on large language models (LLMs, commonly called "AI", short for "artificial intelligence") increased drastically in popularity in 2024. There are privacy and antitrust concerns. Accuracy concerns also exist, and intensify in situations in which tools try to go beyond transcribing and summarizing, and are asked to format information by its meaning, since LLMs do not deal well with meaning (see weak artificial intelligence). Medics using these scribes are generally expected to understand the ethical and legal considerations, and supervise the outputs. The privacy protections of automated medical scribes vary widely. While it is possible to do all the transcription and summarizing locally, with no connection to the internet, most closed-source providers require that data be sent to their own servers over the internet, processed there, and the results sent back (as with digital voice assistants). Some retailers say their tools use zero-knowledge encryption (meaning that the service provider can't access the data). Others explicitly say that they use patient data to train their AIs, or rent or resell it to third parties; the nature of privacy protections used in such situations is unclear, and they are likely not to be fully effective. Most providers have not published any safety or utility data in academic journals, and are not responsive to requests from medical researchers studying their products. == Privacy == Some providers unclear about what happens to user data. Some may sell data to third parties. Some explicitly send user data to for-profit tech companies for secondary purposes, which may not be specified. Some require users to sign consents to such reuse of their data. Some ingest user data to train the software, promising to anonymize it; however, deanonymization may be possible (that is, it may become obvious who the patient is). It is intrinsically impossible to prevent an LLM from correlating its inputs; they work by finding similar patterns across very large data sets. Some information on the patient will be known from other sources (for instance, information that they were injured in an incident on a certain day might be available from the news media; information that they attended specific appointment locations at specific times is probably available to their cellphone provider/apps/data brokers; information about when they had a baby is probably implied by their online shopping records; and they might mention lifestyle changes to their doctor and on a forum or blog). The software may correlate such information with the "anonymized" clinical consultation record, and, asked about the named patient, provide information which they only told their doctor privately. Because a patient's record is all about the same patient, it is all unavoidably linked; in very many cases, medical histories are intrinsically identifiable. Depending on how common a condition and what other data is available, K-anonymity may be useless. Differential privacy could theoretically preserve privacy. Data broker companies like Google, Amazon, Apple and Microsoft have produced or bought up medical scribes, some of which use user data for secondary purposes, which has led to antitrust concerns. Transfer of patient records for AI training has, in the past, prompted legal action. Open-source programs typically do all the transcription locally, on the doctor's own computer. Open-source software is widely used in healthcare, with some national public healthcare bodies holding hack days. === Data resale and commercialization === Several AI medical scribe providers include terms in their service agreements that allow the reuse, sale, or commercialization of de-identified or user-submitted data. Although such data are generally described as anonymized or aggregated, these practices have raised ethical concerns among clinicians and privacy advocates regarding secondary uses of medical information beyond clinical documentation. Freed, an AI transcription and scribe platform, states in its Terms of Use that it may "collect, use, publish, disseminate, sell, transfer, and otherwise exploit" de-identified and aggregated data derived from user inputs. OpenEvidence similarly states that it may "collect, use, transfer, sell, and disclose non-personal information and customer usage data for any purpose including commercial uses." Doximity, which offers an AI-enabled medical scribe as part of its physician platform, grants itself a "nonexclusive, irrevocable, worldwide, perpetual, unlimited, assignable, sublicensable, royalty-free" license to "copy, prepare derivative works from, improve, distribute, publish, ... analyze, index, tag, [and] commercialize" content submitted by users, subject to its privacy policy. Because these terms allow broad secondary use—including sale, licensing, model-training, derivative works, and commercial exploitation of de-identified or user-submitted data—some commentators have recommended that clinicians review data-handling provisions carefully when adopting AI-scribe tools, particularly in clinical environments where patient privacy and regulatory compliance are critical. === Encryption === Multifactor authentication for access to the data is expected practice. Typically, Diffie–Hellman key exchange is used for encryption; this is the standard method commonly used for things like online banking. This encryption is expensive but not impossible to break; it is not generally considered safe against eavesdroppers with the resources of a nation-state. If content is encrypted between the client and the service provider's remote server (transport cryptography), then the server has an unencrypted copy. This is necessary if the data is used by the service provider (for instance, to train the software). Zero-knowledge encryption implies that the only unencrypted copy is at the client, and the server cannot decrypt the data any more easily than a monster-in-the-middle attacker. == Platforms == Scribes may operate on desktops, laptop, or mobile computers, under a variety of operating systems. These vary in their risks; for instance, mobiles can be lost. The underlying mobile or desktop operating systems are also part of the trusted computing base, and if they are not secure, the software relying on them cannot be secure either. Some AI medical scribe platforms are designed to operate as cloud-based applications that generate structured clinical documentation from clinician–patient conversations. These systems may offer features such as real-time transcription, document generation, and integration with electronic health record (EHR) systems. == Confabulation, omissions, and other errors == Like other LLMs, medical-scribe LLMs are prone to hallucinations, where they make up content based on statistically associations between their training data and the transcription audio. LLMs do not distinguish between trying to transcribe the audio and guessing what words will come next, but perform both processes mixed together. They are especially likely to take short silences or non-speech noises and invent some sort of speech to transcribe them as. LLM medical scribes have been known to confabulate racist and otherwise prejudiced content; this is partly because the training datasets of many LLMs contain pseudoscientific texts about medical racism. They may misgender patients. A survey found that most doctors preferred, in principle, that scribes be trained on data reviewed by medical subject experts. Relevant, accurate training data increases the probability of an accurate transcription, but does not guarantee accuracy. Software trained on thousands of real clinical conversations generated transcripts with lower word error rates. Software trained on manually-transcribed training data did better than software trained with automatically transcribed training data such as YouTube captions. Autoscribes omit parts of the conversation classes as irrelevant. The may wrongly classify pertinent information as irrelevant and omit it. They may also confuse historic and current symptoms, or otherwise misclassify information. They may also simply wrongly transcribe the speech, writing something incorrect instead. If clinicians do not carefully check the recording, such mistakes could make their way into their medical records and cause patient harms. == Patient consent == Professional organizations generally require that scribes be used only with patient consent; some bodies may require written consent. Medics must also abide by local surveillance laws, which may criminalize recording pri

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  Teacher forcing

  Teacher forcing is an algorithm for training the weights of recurrent neural networks (RNNs). It involves feeding observed sequence values (i.e. ground-truth samples) back into the RNN after each step, thus forcing the RNN to stay close to the ground-truth sequence. The term "teacher forcing" can be motivated by comparing the RNN to a human student taking a multi-part exam where the answer to each part (for example a mathematical calculation) depends on the answer to the preceding part. In this analogy, rather than grading every answer in the end, with the risk that the student fails every single part even though they only made a mistake in the first one, a teacher records the score for each individual part and then tells the student the correct answer, to be used in the next part. The use of an external teacher signal is in contrast to real-time recurrent learning (RTRL). Teacher signals are known from oscillator networks. The promise is, that teacher forcing helps to reduce the training time. The term "teacher forcing" was introduced in 1989 by Ronald J. Williams and David Zipser, who reported that the technique was already being "frequently used in dynamical supervised learning tasks" around that time. A NeurIPS 2016 paper introduced the related method of "professor forcing".

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  Evolutionary multimodal optimization

  In applied mathematics, multimodal optimization deals with optimization tasks that involve finding all or most of the multiple (at least locally optimal) solutions of a problem, as opposed to a single best solution. Evolutionary multimodal optimization is a branch of evolutionary computation, which is closely related to machine learning. Wong provides a short survey, wherein the chapter of Shir and the book of Preuss cover the topic in more detail. == Motivation == Knowledge of multiple solutions to an optimization task is especially helpful in engineering, when due to physical (and/or cost) constraints, the best results may not always be realizable. In such a scenario, if multiple solutions (locally and/or globally optimal) are known, the implementation can be quickly switched to another solution and still obtain the best possible system performance. Multiple solutions could also be analyzed to discover hidden properties (or relationships) of the underlying optimization problem, which makes them important for obtaining domain knowledge. In addition, the algorithms for multimodal optimization usually not only locate multiple optima in a single run, but also preserve their population diversity, resulting in their global optimization ability on multimodal functions. Moreover, the techniques for multimodal optimization are usually borrowed as diversity maintenance techniques to other problems. == Background == Classical techniques of optimization would need multiple restart points and multiple runs in the hope that a different solution may be discovered every run, with no guarantee however. Evolutionary algorithms (EAs) due to their population based approach, provide a natural advantage over classical optimization techniques. They maintain a population of possible solutions, which are processed every generation, and if the multiple solutions can be preserved over all these generations, then at termination of the algorithm we will have multiple good solutions, rather than only the best solution. Note that this is against the natural tendency of classical optimization techniques, which will always converge to the best solution, or a sub-optimal solution (in a rugged, “badly behaving” function). Finding and maintenance of multiple solutions is wherein lies the challenge of using EAs for multi-modal optimization. Niching is a generic term referred to as the technique of finding and preserving multiple stable niches, or favorable parts of the solution space possibly around multiple solutions, so as to prevent convergence to a single solution. The field of Evolutionary algorithms encompasses genetic algorithms (GAs), evolution strategy (ES), differential evolution (DE), particle swarm optimization (PSO), and other methods. Attempts have been made to solve multi-modal optimization in all these realms and most, if not all the various methods implement niching in some form or the other. == Multimodal optimization using genetic algorithms/evolution strategies == De Jong's crowding method, Goldberg's sharing function approach, Petrowski's clearing method, restricted mating, maintaining multiple subpopulations are some of the popular approaches that have been proposed by the community. The first two methods are especially well studied, however, they do not perform explicit separation into solutions belonging to different basins of attraction. The application of multimodal optimization within ES was not explicit for many years, and has been explored only recently. A niching framework utilizing derandomized ES was introduced by Shir, proposing the CMA-ES as a niching optimizer for the first time. The underpinning of that framework was the selection of a peak individual per subpopulation in each generation, followed by its sampling to produce the consecutive dispersion of search-points. The biological analogy of this machinery is an alpha-male winning all the imposed competitions and dominating thereafter its ecological niche, which then obtains all the sexual resources therein to generate its offspring. Recently, an evolutionary multiobjective optimization (EMO) approach was proposed, in which a suitable second objective is added to the originally single objective multimodal optimization problem, so that the multiple solutions form a weak pareto-optimal front. Hence, the multimodal optimization problem can be solved for its multiple solutions using an EMO algorithm. Improving upon their work, the same authors have made their algorithm self-adaptive, thus eliminating the need for pre-specifying the parameters. An approach that does not use any radius for separating the population into subpopulations (or species) but employs the space topology instead is proposed in.

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