TargetLink is a software for automatic code generation, based on a subset of Simulink/Stateflow models, produced by dSPACE GmbH. TargetLink requires an existing MATLAB/Simulink model to work on. TargetLink generates both ANSI-C and production code optimized for specific processors. It also supports the generation of AUTOSAR-compliant code for software components for the automotive sector. The management of all relevant information for code generation takes place in a central data container, called the Data Dictionary. Testing of the generated code is implemented in Simulink, which is also used for the specification of the underlying simulation models. TargetLink supports three simulation modes to test the generated code: Model-in-the-loop simulation (MIL): this mode allows the model design to be checked. An MIL simulation is also known as a floating-point simulation, since the variables are typically floating-point variables. Software-in-the-loop (SIL): the simulation is based on the execution of generated code, which runs on a PC system. The variables are typically plain or fixed point numbers. Processor-in-the-loop (PIL): in a PIL simulation, the generated code runs on the target hardware or on an evaluation board. So-called real-time frames are included, making it possible to transfer the simulation results as well as memory consumption and runtime information to the PC. The Motor Industry Software Reliability Association (MISRA) published official MISRA modeling guidelines for TargetLink in late 2007, which are particularly important for functional safety of safety-critical applications. In 2009, TÜV SÜD certified TargetLink for use during the development of safety-critical systems to ISO DIS 26262 and IEC 61508.
List of robotics journals
List of robotics journals includes notable academic and scientific journals that focus on research in the field of robotics and automation. == Journals == Acta Mechanica et Automatica Advanced Robotics Annual Review of Control, Robotics, and Autonomous Systems IEEE Robotics and Automation Letters IEEE Transactions on Robotics IEEE Transactions on Field Robotics The International Journal of Advanced Manufacturing Technology International Journal of Humanoid Robotics International Journal of Robotics Research Journal of Cognitive Engineering and Decision Making Journal of Field Robotics Journal of Intelligent & Robotic Systems Paladyn Robotics and Autonomous Systems Robotics Science Robotics SLAS Technology
Semantic network
A semantic network, or frame network is a knowledge base that represents semantic relations between concepts in a network. This is often used as a form of knowledge representation. It is a directed or undirected graph consisting of vertices, which represent concepts, and edges, which represent semantic relations between concepts, mapping or connecting semantic fields. A semantic network may be instantiated as, for example, a graph database or a concept map. Typical standardized semantic networks are expressed as semantic triples. Semantic networks are used in natural language processing applications such as semantic parsing and word-sense disambiguation. Semantic networks can also be used as a method to analyze large texts and identify the main themes and topics (e.g., of social media posts), to reveal biases (e.g., in news coverage), or even to map an entire research field. == History == Examples of the use of semantic networks in logic, directed acyclic graphs as a mnemonic tool, dates back centuries. The earliest documented use being the Greek philosopher Porphyry's commentary on Aristotle's categories in the third century AD. In computing history, "Semantic Nets" for the propositional calculus were first implemented for computers by Richard H. Richens of the Cambridge Language Research Unit in 1956 as an "interlingua" for machine translation of natural languages. Although the importance of this work and the CLRU was only belatedly realized. Semantic networks were also independently implemented by Robert F. Simmons and Sheldon Klein, using the first order predicate calculus as a base, after being inspired by a demonstration of Victor Yngve. The "line of research was originated by the first President of the Association [Association for Computational Linguistics], Victor Yngve, who in 1960 had published descriptions of algorithms for using a phrase structure grammar to generate syntactically well-formed nonsense sentences. Sheldon Klein and I about 1962-1964 were fascinated by the technique and generalized it to a method for controlling the sense of what was generated by respecting the semantic dependencies of words as they occurred in text." Other researchers, most notably M. Ross Quillian and others at System Development Corporation helped contribute to their work in the early 1960s as part of the SYNTHEX project. It's from these publications at SDC that most modern derivatives of the term "semantic network" cite as their background. Later prominent works were done by Allan M. Collins and Quillian (e.g., Collins and Quillian; Collins and Loftus Quillian). Still later in 2006, Hermann Helbig fully described MultiNet. In the late 1980s, two Netherlands universities, Groningen and Twente, jointly began a project called Knowledge Graphs, which are semantic networks but with the added constraint that edges are restricted to be from a limited set of possible relations, to facilitate algebras on the graph. In the subsequent decades, the distinction between semantic networks and knowledge graphs was blurred. In 2012, Google gave their knowledge graph the name Knowledge Graph. The Semantic Link Network was systematically studied as a social semantics networking method. Its basic model consists of semantic nodes, semantic links between nodes, and a semantic space that defines the semantics of nodes and links and reasoning rules on semantic links. The systematic theory and model was published in 2004. This research direction can trace to the definition of inheritance rules for efficient model retrieval in 1998 and the Active Document Framework ADF. Since 2003, research has developed toward social semantic networking. This work is a systematic innovation at the age of the World Wide Web and global social networking rather than an application or simple extension of the Semantic Net (Network). Its purpose and scope are different from that of the Semantic Net (or network). The rules for reasoning and evolution and automatic discovery of implicit links play an important role in the Semantic Link Network. Recently it has been developed to support Cyber-Physical-Social Intelligence. It was used for creating a general summarization method. The self-organised Semantic Link Network was integrated with a multi-dimensional category space to form a semantic space to support advanced applications with multi-dimensional abstractions and self-organised semantic links It has been verified that Semantic Link Network play an important role in understanding and representation through text summarisation applications. Semantic Link Network has been extended from cyberspace to cyber-physical-social space. Competition relation and symbiosis relation as well as their roles in evolving society were studied in the emerging topic: Cyber-Physical-Social Intelligence More specialized forms of semantic networks has been created for specific use. For example, in 2008, Fawsy Bendeck's PhD thesis formalized the Semantic Similarity Network (SSN) that contains specialized relationships and propagation algorithms to simplify the semantic similarity representation and calculations. == Basics of semantic networks == A semantic network is used when one has knowledge that is best understood as a set of concepts that are related to one another. Most semantic networks are cognitively based. They also consist of arcs and nodes which can be organized into a taxonomic hierarchy. Semantic networks contributed ideas of spreading activation, inheritance, and nodes as proto-objects. == Examples == === In Lisp === The following code shows an example of a semantic network in the Lisp programming language using an association list. To extract all the information about the "canary" type, one would use the assoc function with a key of "canary". === WordNet === An example of a semantic network is WordNet, a lexical database of English. It groups English words into sets of synonyms called synsets, provides short, general definitions, and records the various semantic relations between these synonym sets. Some of the most common semantic relations defined are meronymy (A is a meronym of B if A is part of B), holonymy (B is a holonym of A if B contains A), hyponymy (or troponymy) (A is subordinate of B; A is kind of B), hypernymy (A is superordinate of B), synonymy (A denotes the same as B) and antonymy (A denotes the opposite of B). WordNet properties have been studied from a network theory perspective and compared to other semantic networks created from Roget's Thesaurus and word association tasks. From this perspective the three of them are a small world structure. === Other examples === It is also possible to represent logical descriptions using semantic networks such as the existential graphs of Charles Sanders Peirce or the related conceptual graphs of John F. Sowa. These have expressive power equal to or exceeding standard first-order predicate logic. Unlike WordNet or other lexical or browsing networks, semantic networks using these representations can be used for reliable automated logical deduction. Some automated reasoners exploit the graph-theoretic features of the networks during processing. Other examples of semantic networks are Gellish models. Gellish English with its Gellish English dictionary, is a formal language that is defined as a network of relations between concepts and names of concepts. Gellish English is a formal subset of natural English, just as Gellish Dutch is a formal subset of Dutch, whereas multiple languages share the same concepts. Other Gellish networks consist of knowledge models and information models that are expressed in the Gellish language. A Gellish network is a network of (binary) relations between things. Each relation in the network is an expression of a fact that is classified by a relation type. Each relation type itself is a concept that is defined in the Gellish language dictionary. Each related thing is either a concept or an individual thing that is classified by a concept. The definitions of concepts are created in the form of definition models (definition networks) that together form a Gellish Dictionary. A Gellish network can be documented in a Gellish database and is computer interpretable. SciCrunch is a collaboratively edited knowledge base for scientific resources. It provides unambiguous identifiers (Research Resource IDentifiers or RRIDs) for software, lab tools etc. and it also provides options to create links between RRIDs and from communities. Another example of semantic networks, based on category theory, is ologs. Here each type is an object, representing a set of things, and each arrow is a morphism, representing a function. Commutative diagrams also are prescribed to constrain the semantics. In the social sciences people sometimes use the term semantic network to refer to co-occurrence networks. == Software tools == There are also elaborate types of semantic networks connected with corresponding sets of software tools used for
No Fakes Act
The NO FAKES Act or the Nurture Originals, Foster Art, and Keep Entertainment Safe Act, is proposed United States federal legislation concerning digital replicas. The bill was first introduced in 2023 as a discussion draft, formally introduced in 2024, and reintroduced in 2025. If enacted, the bill would establish a federal right of publicity, giving public figures and private individuals greater control over the creation and use of digital replicas of their likenesses, including artificial intelligence (AI)-generated content. If passed, the NO FAKES Act would create a legal framework for licensing digital replicas, including provisions for liability, safe harbors, and statutory exceptions. The proposal has received broad support from the entertainment and technology industries. However, digital rights organizations have raised concerns that the Act risks chilling protected speech. == Background == === Entertainment industry concerns === Actors’ concerns over studios' use of their digital likeness were one of the primary drivers of the Screen Actors Guild–American Federation of Television and Radio Artists (SAG-AFTRA) strike in 2023. Negotiators for SAG-AFTRA alleged that the Alliance of Motion Picture and Television Producers (AMPTP) sought to use the digital likenesses of actors in perpetuity and would try to replace union members, especially background actors. The AMPTP denied SAG-AFTRA's interpretation of its proposal. In November 2023, AMPTP and SAG-AFTRA reached an agreement on the use of actors’ digital replicas, which included requirements for consent and compensation. Recording labels have also expressed concerns over unauthorized digital replicas of their performers' likeness. In 2023, TikTok user Ghostwriter977 released "Heart on My Sleeve," an AI-produced song in the styles of Drake and the Weeknd. After the song received millions of streams, the Universal Music Group (UMG) initiated takedown requests to TikTok and YouTube, which removed the song from their platforms. The legal arguments attorneys made were not disclosed; however, commentators noted that they likely used the Digital Millennium Copyright Act (DMCA). This presented a novel scenario, since UMG did not have licensing rights to "Heart on My Sleeve." According to The Verge, UMG based its DMCA takedown request on an unauthorized sample used at the start of the song for the producer tag. While legal commentators noted that UMG could have asserted a violation of the artists’ rights of publicity, existing state right of publicity laws do not provide notice-and-takedown mechanisms comparable to those under the DMCA. === Legal landscape === Legal scholars have observed that AI-generated digital replicas raise questions under existing copyright and intellectual property law. U.S. copyright law generally requires that original authorship be attributable to a human; however, the extent of human intervention needed to satisfy this requirement is not clear. Copyright holders have filed lawsuits against AI companies alleging unauthorized usage of copyrighted material to train their models, though many of these cases remain pending. In terms of outputs, record labels often hold rights to artists’ musical works but do not necessarily control the artists’ voice, appearance, or likeness in the same way. As a result, AI-generated recordings such as "Heart on My Sleeve" may fall outside the scope of certain traditional copyright protections. Individuals' likenesses have historically been governed under the Lanham Act, the Federal Trade Commission Act, and right of publicity laws. The right of publicity, recognized in many state-level statutes and common law, allows individuals to bring legal claims against unauthorized commercial use of their identities. It has often, but not exclusively, been applied to celebrities or other recognizable individuals. There is no federal-level right to publicity, and state-level protections vary, especially on issues relating to digital replicas and posthumous rights, which makes it difficult for creators or other individuals to prevent unauthorized use of their likenesses. In July 2024, the U.S. Copyright Office released a report on digital replicas and recommended that Congress create a federal law to protect individuals from unauthorized uses of their digital replicas, noting the inadequacy, narrowness, and inconsistency of existing laws. == Provisions == Under the NO FAKES Act of 2025, a digital replica is defined as "a newly created, computer-generated, highly realistic electronic representation that is readily identifiable as the voice or visual likeness of an individual," living or dead. A digital replica can be embodied in sound recordings, images, or audiovisual works in which the individual did not perform or in which the individual did perform but the "fundamental character of the performance or appearance has been materially altered." The Act specifies that digital replicas do not include reproduced samples of works authorized by the copyright holder. The Act defines a "right holder" as either the individual who is the subject of a digital replica or an entity that has acquired the rights to that individual’s likeness. The Act grants right holders the exclusive right to authorize the use of an individual’s likeness in a digital replica. This right is not assignable during the individual’s lifetime; however, it can be licensed to a living individual for up to 10 years under certain conditions. Postmortem rights The Act provides that the right does not automatically expire upon an individual’s death. It may be transferred to executors, heirs, or other parties designated by the individual. The right is held by the right holder for 10 years following the individual’s death. If the right holder demonstrates active use of the digital replica within the 2 years preceding the end of the 10-year term, the right may be extended for an additional 5-year period. These five-year extensions may be renewed for up to 70 years after the individual’s death. Liability The Act establishes liability for individuals who knowingly distribute a digital replica without authorization from the right holder, as well as for entities that make available a service primarily designed to produce unlawful digital replicas. Safe harbor provisions Similar to the Communications Decency Act and the DMCA, the Act establishes safe harbor provisions for online service providers. Providers are shielded from liability if they adopt and inform users of a policy for terminating accounts that repeatedly violate the Act. The NO FAKES Act does not require online services to proactively monitor content. Instead, it creates a notice-and-takedown mechanism under which providers must promptly respond to notifications seeking the removal of unauthorized digital replicas. These safe harbor protections apply only if the online service provider designates an agent with the U.S. Copyright Office to receive notifications of alleged violations. Remedies The NO FAKES Act provides remedies that are similar to those available under U.S. copyright law. Under the Act, individuals may be held liable for either statutory damages of $5,000 or actual damages for creating or distributing an unauthorized digital replica. The legislation also establishes a tiered liability framework for online service providers. Those that make good faith efforts to comply with the Act may face statutory damages of up to $25,000 per work for violations or actual damages. Providers that do not undertake such compliance efforts may be liable for $5,000 per unauthorized display or transmission of a digital replica, with damages capped at $750,000 per work. Exclusions The Act includes several exceptions to liability that are modeled in part on fair use principles. Digital replicas are excluded from liability when "used in a bona fide news, public affairs, or sports broadcast or account;" in a documentary or historical context; or in a way that is "consistent with the public interest." These exclusions do not apply to de minimis uses or to digital replicas that are sexually explicit in nature. The Act further states that licensing requirements do not apply to licenses established through collective bargaining agreements that contain provisions governing the use of digital replicas. The Act does not impose secondary liability on providers of generative artificial intelligence tools or services whose primary purpose is not the creation of unauthorized digital replicas. Preemption The NO FAKES Act preempts laws that protect "an individual's voice and visual likeness rights in connection with a digital replica, as defined in this Act, in an expressive work." However, the Act preserves state laws governing digital replicas enacted before January 2, 2025, as well as state laws addressing digital replicas that portray sexually explicit conduct. == History == In 2023, Senators Marsha Blackburn, Chris Coons, Amy Klobuchar, and Th
Danilo McGarry
Danilo McGarry (born 1985) is a British tech executive, writer, and speaker who has led AI initiatives in finance and healthcare. == Early life and education == Danilo McGarry was born in 1985. He received a Bachelor of Science (BSc) with honors in Business Management from the University of Bath. == Career == McGarry began his career in technology and financial services, with positions at companies including Motorola, JPMorgan Chase, and BNP Paribas. He later joined the Royal Bank of Canada (RBC) as an analyst and later became a director, where he led transformation initiatives involving robotic process automation (RPA) in the bank's capital markets operations. McGarry subsequently moved into leadership roles focused on AI. At Citigroup, he served as Head of Artificial Intelligence and Machine Learning, where he launched an AI-driven robotics and automation initiative. At UnitedHealth Group (UHG), he held a senior role in the company's automation program, which utilized a large fleet of software robots in its healthcare operations. In December 2019, McGarry was appointed Global Head of AI & Automation at Alter Domus, a multinational financial services firm. In this role, he established a new AI and automation department. He left the firm in late 2023 to establish his businesses. In 2025, the Chartered Institute of Personnel and Development (CIPD) appointed him as its strategic adviser on artificial intelligence.
Generative design
Generative design is an iterative design process that uses software to generate outputs that fulfill a set of constraints iteratively adjusted by a designer. Whether a human, test program, or artificial intelligence, the designer algorithmically or manually refines the feasible region of the program's inputs and outputs with each iteration to fulfill evolving design requirements. By employing computing power to evaluate more design permutations than a human alone is capable of, the process is capable of producing an optimal design that mimics nature's evolutionary approach to design through genetic variation and selection. The output can be images, sounds, architectural models, animation, and much more. It is, therefore, a fast method of exploring design possibilities that is used in various design fields such as art, architecture, communication design, and product design. Generative design has become more important, largely due to new programming environments or scripting capabilities that have made it relatively easy, even for designers with little programming experience, to implement their ideas. Additionally, this process can create solutions to substantially complex problems that would otherwise be resource-exhaustive with an alternative approach, making it a more attractive option for problems with a large or unknown solution set. It is also facilitated with tools in commercially available CAD packages. Not only are implementation tools more accessible, but also tools leveraging generative design as a foundation. Recent advancements have led to the development of Deep Generative Design, a framework that integrates topology optimization with deep learning models, such as Generative Adversarial Networks (GANs). Unlike traditional evolutionary methods that primarily focus on engineering performance, this approach uses deep generative models to enhance aesthetic diversity and novelty while simultaneously satisfying engineering constraints. For instance, research by Oh et al. (2019) proposed a framework using Boundary Equilibrium GANs (BEGAN) to generate diverse design options which are then refined through density-based topology optimization, allowing for the exploration of complex design spaces that balance structural integrity with visual variation. In practice, generative design does not solely aim to produce a single optimal solution, but involves iteratively refining the design problem by modifying parameters, constraints, and evaluation criteria within a computational model, resulting in multiple design alternatives from which the designer selects. == Use in architecture == Generative design in architecture is an iterative design process that enables architects to explore a wider solution space with more possibility and creativity. Architectural design has long been regarded as a wicked problem. Compared with traditional top-down design approach, generative design can address design problems efficiently, by using a bottom-up paradigm that uses parametric-defined rules to generate complex solutions. The solution itself then evolves to a good, if not optimal, solution. The advantage of using generative design as a design tool is that it does not construct fixed geometries, but take a set of design rules that can generate an infinite set of possible design solutions. The generated design solutions can be more sensitive, responsive, and adaptive to the problem. Generative design involves rule definition and result analysis that are integrated with the design process. By defining parameters and rules, the generative approach is able to provide optimized solution for both structural stability and aesthetics. Possible design algorithms include cellular automata, shape grammar, genetic algorithm, space syntax, and most recently, artificial neural network. Due to the high complexity of the solution generated, rule-based computational tools, such as finite element method and topology optimisation, are preferred to evaluate and optimise the generated solution. The iterative process provided by computer software enables the trial-and-error approach in design, and involves architects interfering with the optimisation process. Historically precedent work includes Antoni Gaudí's Sagrada Família, which used rule based geometrical forms for structures, and Buckminster Fuller's Montreal Biosphere where the rules were designed to generate individual components, rather than the final product. More recent generative-design cases include Foster and Partners' Queen Elizabeth II Great Court, where the tessellated glass roof was designed using a geometric schema to define hierarchical relationships, and then the generated solution was optimized based on geometrical and structural requirements. == Use in sustainable design == Generative design in sustainable design is an effective approach addressing energy efficiency and climate change at the early design stage, recognizing buildings contribute to approximately one-third of global greenhouse gas emissions and 30%-40% of total building energy use. It integrates environmental principles with algorithms, enabling exploration of countless design alternatives to enhance energy performance, reduce carbon footprints, and minimize waste. A key feature of generative design in sustainable design is its ability to incorporate Building Performance Simulations (BPS) into the design process. Simulation programs such as EnergyPlus, Ladybug Tools,, and so on, combined with generative algorithms, can optimize design solutions for cost-effective energy use and zero-carbon building designs. For example, the GENE_ARCH system used a Pareto algorithm with building energy simulation for the whole building design optimization. Generative design has improved sustainable facade design, as illustrated by the algorithm of cellular automata and daylight simulations in adaptive facade design. In addition, genetic algorithms were used with radiation simulations for energy-efficient photo-voltaic (PV) modules on high-rise building facades. Generative design is also applied to life cycle analysis (LCA), as demonstrated by a framework using grid search algorithms to optimize exterior wall design for minimum environmental impact. Multi-objective optimization embraces multiple diverse sustainability goals, such as interactive kinetic louvers using biomimicry and daylight simulations to enhance daylight, visual comfort, and energy efficiency. The study of PV and shading systems can maximize on-site electricity, improve visual quality, and daylight performance. Artificial intelligence (AI) and machine learning (ML) further improve computation efficiency in complex climate-responsive sustainable design. One study employed reinforcement learning to identify the relationship between design parameters and energy use for a sustainable campus, while other studies tried hybrid algorithms, such as using the genetic algorithm and GANs to balance daylight illumination and thermal comfort under different roof conditions. Other popular AI tools were also integrated, including deep reinforcement learning (DRL) and computer vision (CV), to generate an urban block according to direct sunlight hours and solar heat gains. These AI-driven generative design methods enable faster simulations and design decision making, resulting in designs that are environmentally responsible. == Use in additive manufacturing == Additive manufacturing (AM) is a process that creates physical models directly from three-dimensional (3D) data by joining materials layer by layer. It is used in industries to produce a variety of end-use parts, which are final components designed for direct application in products or systems. AM provides design flexibility and enables material reduction in lightweight applications, such as aerospace, automotive, medical, and portable electronic devices, where minimizing weight is critical for performance. Generative design, one of the four key methods for lightweight design in AM, is commonly applied to optimize structures for specific performance requirements. Generative design can help create optimized solutions that balance multiple objectives, such as enhancing performance while minimizing cost. In design for additive manufacturing (DfAM), multi-objective topology optimization is used to generate a set of candidate solutions. Designers then assess these options using their expertise and key performance indicators (KPIs) to select the best option for implementation. However, integrating AM constraints (e.g., speed of build, materials, build envelope, and accuracy) into generative design remains challenging, as ensuring all solutions are valid is complex. Balancing multiple design objectives while limiting computational costs adds further challenges for designers. To overcome these difficulties, researchers proposed a generative design method with manufacturing validation to improve decision-making efficiency. This method starts with a cons
Mycin
MYCIN was an early backward chaining expert system that used black box to identify bacteria causing severe infections, such as bacteremia and meningitis, and to recommend antibiotics, with the dosage adjusted for patient's body weight — the name derived from the antibiotics themselves, as many antibiotics have the suffix "-mycin". The Mycin system was also used for the diagnosis of blood clotting diseases. MYCIN was developed over five or six years in the early 1970s at Stanford University. It was written in Lisp as the doctoral dissertation of Edward Shortliffe under the direction of Bruce G. Buchanan, Stanley N. Cohen and others. MYCIN emerged from the Stanford Heuristic Programming Project. MYCIN demonstrated the potential for expert systems in building high-performance medical reasoning programs. MYCIN is often viewed as a pioneer in the field of expert systems, even being referred to as the "grandaddy of them all-the one that launched the field" by Dr. Allen Newell. MYCIN led to the EMYCIN expert system shell ("essential MYCIN") for acquiring knowledge, reasoning with it, and explaining the results, without the specific medical knowledge. It can be described as "EMYCIN = Prolog + uncertainty + caching + questions + explanations + contexts - variables". An introduction is in Chapter 16 of Paradigms of Artificial Intelligence Programming (PAIP). == Method == MYCIN operated using a fairly simple inference engine and a knowledge base of ~600 rules by obtaining individual inferential facts identified by experts and encoding such facts as individual production rules. No other AI program at the time contained as much domain-specific knowledge clearly separated from its inference procedures as MYCIN. It would query the physician running the program via a long series of simple yes/no or textual questions. At the end, it provided a list of possible culprit bacteria ranked from high to low based on the probability of each diagnosis, its confidence in each diagnosis' probability, the reasoning behind each diagnosis (that is, MYCIN would also list the questions and rules which led it to rank a diagnosis a particular way), and its recommended course of drug treatment. MYCIN could additionally respond to queries by physicians related to why it asked the user a certain question, how it arrived at a conclusion, and why it did not consider certain factors. The developers performed studies showing that MYCIN's performance was minimally affected by perturbations in the uncertainty metrics associated with individual rules, suggesting that the power in the system was related more to its knowledge representation and reasoning scheme than to the details of its numerical uncertainty model. Some observers felt that it should have been possible to use classical Bayesian statistics. MYCIN's developers argued that this would require either unrealistic assumptions of probabilistic independence, or require the experts to provide estimates for an unfeasibly large number of conditional probabilities. Subsequent studies later showed that the certainty factor model could indeed be interpreted in a probabilistic sense, and highlighted problems with the implied assumptions of such a model. However the modular structure of the system would prove very successful, leading to the development of graphical models such as Bayesian networks. === Context === A context in MYCIN determines what types of objects can be reasoned about. They are similar to variables in Prolog, or environment variables in operating systems. === Evidence combination === In MYCIN it was possible that two or more rules might draw conclusions about a parameter with different weights of evidence. For example, one rule may conclude that the organism in question is E. Coli with a certainty of 0.8 whilst another concludes that it is E. Coli with a certainty of 0.5 or even −0.8. In the event the certainty is less than zero the evidence is actually against the hypothesis. In order to calculate the certainty factor MYCIN combined these weights using the formula below to yield a single certainty factor: C F ( x , y ) = { X + Y − X Y if X , Y > 0 X + Y + X Y if X , Y < 0 X + Y 1 − min ( | X | , | Y | ) otherwise {\displaystyle CF(x,y)={\begin{cases}X+Y-XY&{\text{if }}X,Y>0\\X+Y+XY&{\text{if }}X,Y<0\\{\frac {X+Y}{1-\min(|X|,|Y|)}}&{\text{otherwise}}\end{cases}}} Where X and Y are the certainty factors. This formula can be applied more than once if more than two rules draw conclusions about the same parameter. It is commutative, so it does not matter in which order the weights were combined. The combination formula was designed to have the following desirable properties: −1 can be interpreted as "false", +1 as "true", and 0 as "uncertain". Combining unknown with anything leaves it unchanged. Combining true with anything (except false) gives true. Similarly for false. Combining true and false is a division-by-zero error. Combining +x and -x gives unknown. Combining two positives (except true) gives a larger positive. Similarly for negatives. Combining a positive and a negative gives something in between. === Examples === The following examples come from Chapter 16 of PAIP, which contains an implementation in Common Lisp of a modified and simplified version of MYCIN for pedagogical purposes. A rule, and an English paraphrase generated by the system: == Results == An evaluation of MYCIN was conducted at the Stanford Medical School. The first phase of the evaluation consisted of 10 test cases of diverse origin, chosen by a physician who was not acquainted with MYCIN's methods or knowledge base. These cases were presented to 7 physicians and 1 senior medical student. 10 prescriptions were compiled for each of the cases, 1 recommended by MYCIN, 1 prescribed by the treating physician at the county hospital, and 8 by the aforementioned individuals. The second phase of the evaluation consisted of eight infectious disease specialists being provided the clinical summary and set of 10 prescriptions for each of the 10 cases and tasked to provide their own recommendations for each case and assess the 10 prescriptions. MYCIN received an acceptability rating of 65%, which was comparable to the 42.5% to 62.5% rating of five faculty members. This study is often cited as showing the potential for disagreement about therapeutic decisions, even among experts, when there is no "gold standard" for correct treatment. == Practical use == MYCIN was never actually used in practice. This wasn't because of any weakness in its performance. Some observers raised ethical and legal issues related to the use of computers in medicine, regarding the responsibility of the physicians in case the system gave wrong diagnosis. However, the greatest problem, and the reason that MYCIN was not used in routine practice, was the state of technologies for system integration, especially at the time it was developed. MYCIN was a stand-alone system that required a user to enter all relevant information about a patient by typing in responses to questions MYCIN posed. MYCIN ran on the DEC KI10 PDP-10, supporting a large time-shared system available over the early Internet (ARPANet), before personal computers were developed. MYCIN's greatest influence was accordingly its demonstration of the power of its representation and reasoning approach. Rule-based systems in many non-medical domains were developed in the years that followed MYCIN's introduction of the approach. In the 1980s, expert system "shells" were introduced (including one based on MYCIN, known as E-MYCIN (followed by Knowledge Engineering Environment - KEE)) and supported the development of expert systems in a wide variety of application areas. A difficulty that rose to prominence during the development of MYCIN and subsequent complex expert systems has been the extraction of the necessary knowledge for the inference engine to use from the human expert in the relevant fields into the rule base (the so-called "knowledge acquisition bottleneck").