Infomax', or the principle of maximum information preservation, is an optimization principle for artificial neural networks and other information processing systems. It prescribes that a function that maps a set of input values x {\displaystyle x} to a set of output values z ( x ) {\displaystyle z(x)} should be chosen or learned so as to maximize the average Shannon mutual information between x {\displaystyle x} and z ( x ) {\displaystyle z(x)} , subject to a set of specified constraints and/or noise processes. Infomax algorithms are learning algorithms that perform this optimization process. The principle was described by Linsker in 1988. The objective function is called the InfoMax objective. As the InfoMax objective is difficult to compute exactly, a related notion uses two models giving two outputs z 1 ( x ) , z 2 ( x ) {\displaystyle z_{1}(x),z_{2}(x)} , and maximizes the mutual information between these. This contrastive InfoMax objective is a lower bound to the InfoMax objective. Infomax, in its zero-noise limit, is related to the principle of redundancy reduction proposed for biological sensory processing by Horace Barlow in 1961, and applied quantitatively to retinal processing by Atick and Redlich. == Applications == (Becker and Hinton, 1992) showed that the contrastive InfoMax objective allows a neural network to learn to identify surfaces in random dot stereograms (in one dimension). One of the applications of infomax has been to an independent component analysis algorithm that finds independent signals by maximizing entropy. Infomax-based ICA was described by (Bell and Sejnowski, 1995), and (Nadal and Parga, 1995).
Wix.com
Wix.com Ltd. (Hebrew: וויקס.קום, romanized: wix.com) or simply Wix is an Israeli software company, publicly listed in the US, that provides cloud-based web development services. It offers tools for creating HTML5 websites for desktop and mobile platforms using online drag-and-drop editing. Along with its headquarters and other offices in Israel, Wix also has offices in Brazil, Canada, Germany, India, Ireland, Japan, Lithuania, Poland, the Netherlands, the United States, Ukraine, and Singapore. Users can add applications for social media, e-commerce, online marketing, contact forms, e-mail marketing, and community forums to their websites. The Wix website builder is built on a freemium business model, earning its revenues through premium upgrades. According to the W3Techs technology survey website, Wix was used by 2.5% of websites as of September 2023; at the end of May 2025, it was 3.8%. == History == === Corporate affairs === Wix was founded in 2006 by Israeli developers Avishai Abrahami, Nadav Abrahami, and Giora Kaplan. With its main offices in Tel Aviv, Wix was backed by investors Insight Venture Partners, Mangrove Capital Partners, Bessemer Venture Partners, DAG Ventures, and Benchmark Capital. By April 2010, Wix had 3.5 million users and raised US$10 million in Series C funding provided by Benchmark Capital and existing investors Bessemer Venture Partners and Mangrove Capital Partners. In March 2011, Wix had 8.5 million users and raised US$40 million in Series D funding, bringing its total funding to that date to US$61 million. By August 2013, the Wix platform had more than 34 million registered users. On 5 November 2013, Wix had an initial public offering on NASDAQ, raising about US$127 million for the company and some share holders. In 2016, Mark Tluszcz became the chair of the board of directors. In 2020, Wix's revenue increased to $989 million, a 30% rise year-on-year, primarily due to the shift of businesses online during the coronavirus pandemic. The company added over 31 million new registered users in 2020, reaching a total of 196.7 million by year's end. Wix added approximately 1 million net new premium subscriptions in 2020, surpassing $1 billion in annual collections for the first time. By the end of the year, there were 5.5 million premium subscriptions, a 22% increase compared to the end of 2019. As of its most recent reporting in June 2024, Wix has over 260 million users worldwide. === Product development === ==== 2000s ==== Wix entered an open beta phase in 2007 using a platform based on Adobe Flash. ==== 2010s ==== In June 2011, Wix launched the Facebook store module, making its first step into social commerce. In March 2012, Wix launched a new HTML5 site builder, replacing the Adobe Flash technology. In October 2012, Wix launched an app market for users to sell applications built with the company's automated web development technology. In August 2014, Wix launched Wix Hotels, a booking system for hotels, bed and breakfasts, and vacation rentals that use Wix websites. In June 2016, Wix introduced Wix ADI (Artificial Design Intelligence), a platform that uses artificial intelligence to design websites. ==== 2020s ==== In 2020, Wix launched an additional CMS, EditorX, which included additional CSS features to the original builder. In July 2023, Wix announced that it would be building on its ADI technology to create an AI powered website generator In October 2023, Wix launched the Wix Studio website builder. Co-founder and CEO, Avishai Abrahami described the platform as a “product for agencies”. In March 2024, the AI web builder, which uses a chatbot to help users create content was launched to the public. In March 2025, the digital publisher CNET has identified Wix as the "Best overall website builder overall." In August 2025, Wix announced it would launch banking services—including checking accounts and loans for small businesses—via a partnership with Israeli fintech Unit Finance, as it sought to diversify amid what it described as threats to its core website-building business from artificial intelligence. In January 2026, Wix launched Wix Harmony. Wix harmony is an AI website builder that uses agentic technology, generative design and vibe coding—with manual editing features for additional control. In May 2026, Wix announced layoffs affecting approximately 1,000 employees, or 20% of its workforce. CEO Avishai Abrahami cited two factors: the need to restructure around artificial intelligence and the appreciation of the Israeli shekel against the US dollar, which increased the cost of its Israel-based workforce relative to its dollar-denominated revenue. === Acquisitions === In April 2014, Wix announced the acquisition of Appixia, an Israeli startup for creating native mobile commerce (mCommerce) apps. In October 2014, Wix announced its acquisition of OpenRest, a developer of online ordering systems for restaurants. In April 2015, Wix acquired Moment.me, a mobile website builder for events and marketing tools for social lead generation. On 23 February 2017, Wix acquired the online art community DeviantArt for US$36 million. In January 2017, the company acquired Flok, a provider of customer loyalty programs tools. In February 2020, Wix acquired Inkfrog for eBay sellers, a web design company that provides customized business management software for eBay sellers. On 2 March 2021, Wix acquired SpeedETab, a Miami-based restaurant online technology provider. In May 2021, Wix acquired Rise.ai, a gift card and customer re-engagement package for online brands. A month later, Wix acquired Modalyst, a marketplace and drop-shipping platform. In May 2025, Wix acquired Hour One, a startup specializing in AI-powered video creation tools, to enhance its generative AI capabilities. In June 2025, the company acquired Base44, owned by independent entrepreneur Maor Shlomo, with the intention of integrating Base44's artificial intelligence capabilities and conversational interface into Wix's website and app building platform. == Description == Wix uses a freemium business model. Users can create websites for free then must purchase premium packages to connect their sites to their own domains, remove Wix ads, access the form builder, add e-commerce capabilities, or buy extra data storage and bandwidth. Wix provides customizable website templates and a drag-and-drop HTML5 website builder that includes apps, graphics, image galleries, fonts, vectors, animations, and other options. Users also may opt to create their web sites from scratch. In October 2013, Wix introduced a mobile editor for mobile viewing customization. Wix App Market offers both free and subscription-based applications, with a revenue split of 80% for the developer and 20% for Wix. Customers can integrate third-party applications into their own web sites, such as photograph feeds, blogging, music playlists, online community, e-mail marketing, and file management. Custom JavaScript code can be inserted into Wix webpages using the Velo API. == Controversies == === Use of WordPress code === In October 2016, there was a controversy over Wix's use of WordPress's GPL-licensed code. In response, Avishai Abrahami, Wix's CEO, published a response describing which open-source code was used and how Wix says it collaborates with the open-source community. However, it was subsequently noted that collaboration with the open-source community was not sufficient under the terms of the GPL license, which requires any code built on GPL-licensed code to be released under the same license. === Censorship === On 31 May 2021, 2021 Hong Kong Charter, a Wix-hosted website run by exiled Hong Kong activists, was shut down at the request of the Hong Kong Police. This was the first known case of Hong Kong's National Security Law being used to censor content on an overseas website. Wix later apologized for "mistakenly removing the website" and reinstated the website after it had been down for four days. In October 2023, Wix fired an employee in Dublin, Ireland, for having made social media posts critical of Israel. This incident led to criticism of Wix from members of the Oireachtas (the Irish parliament) and from the head of the Irish government, Taoiseach Leo Varadkar, who said it was "not okay to dismiss somebody because of their political views". Deputy head of government, Tánaiste Micheál Martin, also condemned their dismissal, stating "we tolerate debate with freedom of speech, freedom of opinion, and people have different opinions on these issues." The dismissed employee, Courtney Carey, successfully sued the company for unfair dismissal. Wix did not contest the charge, admitting liability. === Outreach abroad === In October 2023, The Irish Times reported that an Israeli advertising agency advised Wix staff how they can tailor posts for "outreach abroad". This included advice for Wix employees to “show Westernity” in social media posts supporting Israel, stating that “unlike the Gazans,
Catholic Church and artificial intelligence
The Catholic Church views artificial intelligence as a significant technological development that must be governed by strict ethical principles rooted in human dignity and the common good. In January 2025, the Church issued the doctrinal note Antiqua et nova co-issued by the Dicastery for the Doctrine of the Faith and the Dicastery for Culture and Education. It addresses the "relationship between artificial intelligence and human intelligence" and offers reflections on the "anthropological and ethical challenges raised by AI". In August 2025, Time magazine included Pope Leo XIV in its 2025 list of the World’s Most Influential People in Artificial Intelligence. In May 2026, Pope Leo XIV approved the creation of a new Vatican commission on artificial intelligence. He released his first papal encyclical, titled Magnifica humanitas, on the topic later in the month.
Logic Theorist
Logic Theorist is a computer program completed in 1956 by Allen Newell, Herbert A. Simon, and Cliff Shaw. It was the first program deliberately engineered to perform automated reasoning, and has been described as "the first artificial intelligence program". Logic Theorist proved 38 of the first 52 theorems in chapter two of Whitehead and Bertrand Russell's Principia Mathematica, and found new and shorter proofs for some of them. == History == In 1955, when Newell and Simon began to work on the Logic Theorist, the field of artificial intelligence did not yet exist; the term "artificial intelligence" would not be coined until the following summer. Simon was a political scientist who had previously studied the way bureaucracies function as well as developing his theory of bounded rationality (for which he would later win the Nobel Memorial Prize in Economic Sciences in 1978). He believed the study of business organizations requires, like artificial intelligence, an insight into the nature of human problem solving and decision making. Simon has stated that when consulting at RAND Corporation in the early 1950s, he saw a printer typing out a map, using ordinary letters and punctuation as symbols. This led him to think that a machine that could manipulate symbols could simulate decision making and possibly even the process of human thought. The program that printed the map had been written by Newell, a RAND scientist studying logistics and organization theory. For Newell, the decisive moment was in 1954 when Oliver Selfridge came to RAND to describe his work on pattern matching. Watching the presentation, Newell suddenly understood how the interaction of simple, programmable units could accomplish complex behavior, including the intelligent behavior of human beings. "It all happened in one afternoon," he would later say. It was a rare moment of scientific epiphany. "I had such a sense of clarity that this was a new path, and one I was going to go down. I haven't had that sensation very many times. I'm pretty skeptical, and so I don't normally go off on a toot, but I did on that one. Completely absorbed in it—without existing with the two or three levels consciousness so that you're working, and aware that you're working, and aware of the consequences and implications, the normal mode of thought. No. Completely absorbed for ten to twelve hours." Newell and Simon began to talk about the possibility of teaching machines to think. Their first project was a program that could prove mathematical theorems like the ones used in Bertrand Russell and Alfred North Whitehead's Principia Mathematica. They enlisted the help of computer programmer Cliff Shaw, also from RAND, to develop the program. (Newell says "Cliff was the genuine computer scientist of the three".) The first version was hand-simulated: they wrote the program onto 3x5 cards and, as Simon recalled:In January 1956, we assembled my wife and three children together with some graduate students. To each member of the group, we gave one of the cards, so that each one became, in effect, a component of the computer program ... Here was nature imitating art imitating nature. They succeeded in showing that the program could successfully prove theorems as well as a talented mathematician. Eventually Shaw was able to run the program on the computer at RAND's Santa Monica facility. In the summer of 1956, John McCarthy, Marvin Minsky, Claude Shannon and Nathan Rochester organized a conference on the subject of what they called "artificial intelligence" (a term coined by McCarthy for the occasion). Newell and Simon proudly presented the group with the Logic Theorist. It was met with a lukewarm reception. Pamela McCorduck writes "the evidence is that nobody save Newell and Simon themselves sensed the long-range significance of what they were doing." Simon confides that "we were probably fairly arrogant about it all" and adds: They didn't want to hear from us, and we sure didn't want to hear from them: we had something to show them! ... In a way it was ironic because we already had done the first example of what they were after; and second, they didn't pay much attention to it. Logic Theorist soon proved 38 of the first 52 theorems in chapter 2 of the Principia Mathematica. The proof of theorem 2.85 was actually more elegant than the proof produced laboriously by hand by Russell and Whitehead (2026-03-20: What is called here Theorem 2.85 is, in fact, numbered as 2.53 in the page 107 of the 1963 Cambridge University Press edition (https://www.uhu.es/francisco.moreno/gii_mac/docs/Principia_Mathematica_vol1.pdf) and which appears, under the same 2.53 number, on page 112 of the 1910 CUP Edition, according to the digitalization on wikibooks (https://en.wikisource.org/wiki/Russell_%26_Whitehead%27s_Principia_Mathematica/Part_1/Section_A#Discussion_2)). Simon was able to show the new proof to Russell himself who "responded with delight". They attempted to publish the new proof in The Journal of Symbolic Logic, but it was rejected on the grounds that a new proof of an elementary mathematical theorem was not notable, apparently overlooking the fact that one of the authors was a computer program. Newell and Simon formed a lasting partnership, founding one of the first AI laboratories at the Carnegie Institute of Technology and developing a series of influential artificial intelligence programs and ideas, including the General Problem Solver, Soar, and their unified theory of cognition. == Architecture == The Logic Theorist is a program that performs logical processes on logical expressions. The Logic Theorist operates on the following principles: === Expressions === An expression is made of elements. There are two kinds of memories: working and storage. Each working memory contains a single element. The Logic Theorist usually uses 1 to 3 working memories. Each storage memory is a list representing a full expression or a set of elements. In particular, it contains all the axioms and proven logical theorems. An expression is an abstract syntax tree, each node being an element with up to 11 attributes. For example, the logical expression ¬ P → ( Q ∧ ¬ P ) {\displaystyle \neg P\to (Q\wedge \neg P)} is represented as a tree with a root element representing → {\displaystyle \to } . Among the attributes of the root element are pointers to the two elements representing the subexpressions ¬ P {\displaystyle \neg P} and Q ∧ ¬ P {\displaystyle Q\wedge \neg P} . === Processes === There are four kinds of processes, from the lowest to the highest level. Instruction: These are similar to assembly code. They may either perform a primitive operation on an expression in working memory, or perform a conditional jump to another instruction. An example is "put the right sub-element of working-memory 1 to working-memory 2" Elementary process: These are similar to subroutines. A sequence of instructions that can be called. Method: A sequence of elementary processes. There are 4 methods: substitution: given an expression, it attempts to transform it to a proven theorem or axiom by substitutions of variables and logical connectives. detachment: given expression B {\displaystyle B} , it attempts to find a proven theorem or axiom of form A → B ′ {\displaystyle A\to B'} , where B ′ {\displaystyle B'} yields B {\displaystyle B} after substitution, then attempts to prove A {\displaystyle A} by substitution. chaining forward: given expression A → C {\displaystyle A\to C} , it attempts to find for a proven theorem or axiom of form A → B {\displaystyle A\to B} , then attempt to prove B → C {\displaystyle B\to C} by substitution. chaining backward: given expression A → C {\displaystyle A\to C} , it attempts to find for a proven theorem or axiom of form B → C {\displaystyle B\to C} , then attempt to prove A → B {\displaystyle A\to B} by substitution. executive control method: This method applies each of the 4 methods in sequence to each theorem to be proved. == Logic Theorist's influence on AI == Logic Theorist introduced several concepts that would be central to AI research: Reasoning as search Logic Theorist explored a search tree: the root was the initial hypothesis, each branch was a deduction based on the rules of logic. Somewhere in the tree was the goal: the proposition the program intended to prove. The pathway along the branches that led to the goal was a proof – a series of statements, each deduced using the rules of logic, that led from the hypothesis to the proposition to be proved. Heuristics Newell and Simon realized that the search tree would grow exponentially and that they needed to "trim" some branches, using "rules of thumb" to determine which pathways were unlikely to lead to a solution. They called these ad hoc rules "heuristics", using a term introduced by George Pólya in his classic book on mathematical proof, How to Solve It. (Newell had taken courses from Pólya at Stanford). Heuristics would become an important area o
Google Nest
Google Nest, formerly branded Google Home, is a line of smart home products including smart speakers, smart displays, streaming devices, thermostats, smoke detectors, routers and security systems including smart doorbells, cameras and smart locks. The Nest brand name was originally owned by Nest Labs, co-founded by former Apple engineers Tony Fadell and Matt Rogers in 2010. Its flagship product, which was the company's first offering, is the Nest Learning Thermostat, introduced in 2011. The product is programmable, self-learning, sensor-driven, and Wi-Fi-enabled: features that are often found in other Nest products. It was followed by the Nest Protect smoke and carbon monoxide detectors in October 2013. After its acquisition of Dropcam in 2014, the company introduced its Nest Cam branding of security cameras beginning in June 2015. The company quickly expanded to more than 130 employees by the end of 2012. Google acquired Nest Labs for US$3.2 billion in January 2014, when the company employed 280. As of late 2015, Nest employs more than 1,100 and added a primary engineering center in Seattle. After Google reorganized itself under the holding company Alphabet Inc., Nest operated independently of Google from 2015 to 2018. However, in 2018, Nest was merged into Google's home-devices unit led by Rishi Chandra, effectively ceasing to exist as a separate business. In July 2018, it was announced that all Google Home electronics products will henceforth be marketed under the brand Google Nest. == History == === Nest Labs before acquisition by Google === Nest Labs was founded in 2010 by former Apple engineers Tony Fadell and Matt Rogers. The idea came when Fadell was building a vacation home and found all of the available thermostats on the market to be inadequate, motivated to bring something better on the market. Early investors in Nest Labs included Shasta Ventures and Kleiner Perkins. === Acquisition by Google of Nest Labs, Dropcam, and Revolv === On January 13, 2014, Google announced plans to acquire Nest Labs for $3.2 billion in cash. Google completed the acquisition the next day, on January 14, 2014. The company would operate independently from Google's other businesses. In June 2014, it was announced that Nest would buy camera startup Dropcam for $555 million. With the purchase, Dropcam became integrated with other Nest products; if the Protect alarm is triggered, the Dropcam can automatically start recording, and the Thermostat can use Dropcam to sense for motion. In September 2014, the Nest Thermostat and Nest Protect (a smoke alarm) became available in Belgium, France, Ireland, and the Netherlands. Initially, they were sold in approximately 400 stores across Europe, with another 150 stores to be added by the end of the year. In June 2015, the new Nest Cam, replacing the Dropcam, was announced, together with the second generation of the Nest Protect; there were internal reports that sales of the rebranded camera fell. On October 24, 2014, Nest both acquired the hub service Revolv, and discontinued its product line, gaining the expertise of Revolv's staff. === Nest as a subsidiary of Alphabet Inc. === In August 2015, Google announced that it would restructure its operations under a new parent company, Alphabet Inc., with Nest being separated from Google as a subsidiary of the new holding company. In January 2016, some Nest thermostats stopped working, a fault attributed to a software update from two weeks earlier. There were no lawsuits, individual or class-action, due to an arbitration clause in the contract. All Revolv smart hubs, costing several hundred dollars, were deliberately remotely bricked on May 15, 2016; notice was posted on the company's website in February. The story became news on April 4. The "lifetime subscription" to Revolv's online service, which had been sold with the hub, was defined by Nest to be the lifetime of the device, which ended May 15. Nest's decision to brick the hubs, and its "acerbic" corporate culture, faced substantial criticism from within Google/Alphabet and in press coverage. Many of Nest's staffers came from Dropcam and Revolv, and by November 2015, about 70 of about 1000 staffers had quit, causing management concern. Some countermeasures had been taken in takeover deals, to financially discourage senior people from leaving before set dates. Of the ~100 Dropcam staffers, about half had left by March 2016, when former Dropcam CEO Greg Duffy (who left 8 months after the takeover) wrote a post openly regretting selling his company to Nest. He stated that about 500 people had left (of a 1200-person staff). On June 6, 2016, Tony Fadell, the Nest CEO, announced in a blog post that he was leaving the company he founded with Matt Rogers and stepping into an "advisory" role. At this point the Nest acquisition was described by some press as a "disaster" for Google. As of mid-June 2016, Nest's problems were considered symptomatic of the limited market for home automation. According to Frank Gillet of Forrester Research, only 6% of American households possessed internet-connected devices such as appliances, home-monitoring systems, speakers, or lighting. He also predicted this percentage would grow to only 15% by 2021. Furthermore, 72% of respondents in a 2016 British survey conducted by Pricewaterhouse Coopers did not foresee adopting smart-home technology over the next two to five years. === Nest as a part of Google hardware division === On February 7, 2018, it was announced by hardware head Rick Osterloh that Nest had been merged into Google's hardware division, directly alongside units such as Google Home and Chromecast. It would retain its separate Palo Alto headquarters, but Nest CEO Marwan Fawaz would now report to Osterloh, and there were plans for tighter integration with Google platforms and software such as Google Assistant in future products. Shortly after the announcement, co-founder and chief product officer Matt Rogers announced his plans to leave the company. On July 18, 2018, Nest CEO Marwan Fawaz stepped down. Nest was merged with Google's home devices team, led by Rishi Chandra. During the Google I/O keynote on May 7, 2019, it was announced that Google Nest will now serve as the blanket branding for all of Google's home products. The Google Home Hub was retroactively renamed Google Nest Hub, while a new and larger version of the product is now available called the Nest Hub Max with both a larger screen and an amplified speaker, for a greater low-end audio experience. Also, product lines such as Chromecast, Google Home, and Google Wifi will now be marketed under the Google Nest brand. In addition, Nest began to deprecate its own internal platforms, announcing the discontinuation of the existing "Works with Nest" program in favor of Google Assistant going forward, and pushing users to migrate themselves from Nest's account system to Google accounts. Google published Nest-specific privacy information outlining a commitment to transparency, not selling personal information, and giving users control of their data. In February 2019, a privacy incident affecting the Google Nest Guard system came about. The controversy stemmed from the fact that Nest Guard, a security device that was part of the Nest Secure system, contained a hidden microphone that was not disclosed in any product specifications. It resulted in a public relations failure. === Partnership with ADT === In August 2020 Google announced intent to invest $450 million in ADT Inc. for a 6.6% stake in the company. The companies intend to integrate Nest devices with ADT's security monitoring services and eventually make them the “cornerstone of ADT’s smart home offering”, according to Nest. Upon the announcement, the shares of ADT doubled in value and hit all-time high of $17.21. === Use with Amazon Alexa === As of mid-2022, Google's newer Nest cameras will now work with Amazon Alexa devices such as Amazon Echo Show, Fire TV, and Fire Tablet to view captured security camera footage. === End of support policies === On October 25, 2025, software support was ended for the 1st and 2nd generation Nest Learning Thermostats. In addition, most of the smart functionality including the Home Away features, notifications, and carbon monoxide sensor became inoperative as they were dependent on connection with Google servers. By mid-November, third-party software solutions became available to restore functionality to affected thermostats. == Products == === Nest Learning Thermostat === The Nest Learning Thermostat is an electronic, programmable, and self-learning Wi-Fi-enabled thermostat that optimizes heating and cooling of homes and businesses to conserve energy. It is based on a machine-learning algorithm: for the first weeks users have to regulate the thermostat in order to provide the reference data set. Nest can then learn people's schedules, at which temperature they are used to and when. Using built-in sensors and phones' locations it can
Adobe InDesign
Adobe InDesign is a desktop publishing and page layout designing software application produced by Adobe and first released in 1999. It can be used to create works such as posters, flyers, brochures, magazines, newspapers, presentations, books and ebooks. InDesign can also publish content suitable for tablet devices in conjunction with Adobe Digital Publishing Suite. Graphic designers and production artists are the principal users. InDesign is the successor to PageMaker, which Adobe acquired by buying Aldus Corporation in late 1994. (Freehand, Aldus's competitor to Adobe Illustrator, was licensed from Altsys, the maker of Fontographer.) By 1998, PageMaker had lost much of the professional market to the comparatively feature-rich QuarkXPress version 3.3, released in 1992, and version 4.0, released in 1996. In 1999, Quark announced its offer to buy Adobe and to divest the combined company of PageMaker to avoid problems under United States antitrust law. Adobe declined Quark's offer and continued to develop a new desktop publishing application. Aldus had begun developing a successor to PageMaker, code-named "Shuksan". Later, Adobe code-named the project "K2", and Adobe released InDesign 1.0 in 1999. InDesign exports documents in Adobe's Portable Document Format (PDF) and supports multiple languages. It was the first DTP application to support Unicode character sets, advanced typography with OpenType fonts, advanced transparency features, layout styles, optical margin alignment, and cross-platform scripting with JavaScript. Later versions of the software introduced new file formats. To support the new features, especially typography, introduced with InDesign CS, the program and its document format are not backward-compatible. Instead, InDesign CS2 introduced the INX (.inx) format, an XML-based document representation, to allow backward compatibility with future versions. InDesign CS versions updated with the 3.1 April 2005 update can read InDesign CS2-saved files exported to the .inx format. The InDesign Interchange format does not support versions earlier than InDesign CS. With InDesign CS4, Adobe replaced INX with InDesign Markup Language (IDML), another XML-based document representation. InDesign was the first native Mac OS X publishing software. With the third major version, InDesign CS, Adobe increased InDesign's distribution by bundling it with Adobe Photoshop, Adobe Illustrator, and Adobe Acrobat in Adobe Creative Suite. Adobe developed InDesign CS3 (and Creative Suite 3) as universal binary software compatible with native Intel and PowerPC Macs in 2007, two years after the announced 2005 schedule, inconveniencing early adopters of Intel-based Macs. Adobe CEO Bruce Chizen said, "Adobe will be first with a complete line of universal applications." == File format == The MIME type is not official File Open formats: indd, indl, indt, indb, inx, idml, pmd, xqx New File formats: indd, indl, indb File Save As formats: indd, indt Save file format for InCopy: icma (Assignment file) icml (Content file, Exported file) icap (Package for InCopy) idap (Package for InDesign) File Export formats: pdf, idml, icml, eps, jpg, txt, XML, rtf == Versions == Newer versions can, as a rule, open files created by older versions, but the reverse is not true. Current versions can export the InDesign file as an IDML file (InDesign Markup Language), which can be opened by InDesign versions from CS4 upwards; older versions from CS4 down can export to an INX file (InDesign Interchange format). === Server version === In October 2005, Adobe released InDesign Server CS2, a modified version of InDesign (without a user interface) for Windows and Macintosh server platforms. It does not provide any editing client; rather, it is for use by developers in creating client-server solutions with the InDesign plug-in technology. In March 2007 Adobe officially announced Adobe InDesign CS3 Server as part of the Adobe InDesign family. == Features == Paragraph styles are an essential tool for designers when working with text in Adobe InDesign. Despite their menacing appearance, they are straightforward to operate. Other features that make InDesign a good tool for working with text and paragraphs include: Creating frames and shapes Aligning objects with grids and guides Manipulating objects Organizing objects Importing text Formatting text Spell checking Importing images Parent pages (formerly master pages) Paragraph styles == Internationalization and localization == InDesign Middle Eastern editions have unique settings for laying out Arabic or Hebrew text. They feature: Text settings: Special settings for laying out Arabic or Hebrew text, such as: Ability to use Arabic, Persian or Hindi digits; Use kashidas for letter spacing and full justification; Ligature option; Adjust the position of diacritics, such as vowels of the Arabic script; Justify text in three possible ways: Standard, Arabic, Naskh; Option to insert special characters, including Geresh, Gershayim, Maqaf for Hebrew and Kashida for Arabic texts; Apply standard, Arabic, or Hebrew styles for page, paragraph, and footnote numbering. Bi-directional text flow: Right-to-left behavior applies to several objects: Story, paragraph, character, and table. It allows mixing right-to-left and left-to-right words, paragraphs, and stories in a document. Changing the direction of neutral characters (e.g., / or ?) is possible according to the user's keyboard language. Table of contents: Provides a table of contents titles, one for each supported language. This table is sorted according to the chosen language. InDesign CS4 Middle Eastern versions allow users to select the language of the index title and cross-references. Indices: This allows the creation of a simple keyword index or a somewhat more detailed index of the information in the text using embedded indexing codes. Unlike more sophisticated programs, InDesign cannot insert character style information as part of an index entry (e.g., when indexing book, journal, or movie titles). Indices are limited to four levels (the top level and three sub-levels). Like tables of contents, indices can be sorted according to the selected language. Importing and exporting: Can import QuarkXPress files up to version 4.1 (1999), even using Arabic XT, Arabic Phonyx, or Hebrew XPressWay fonts, retaining the layout and content. Includes 50 import/export filters, including a Microsoft Word 97-98-2000 import filter and a plain text import filter. Exports IDML files can be read by QuarkXPress 2017. Reverse layout: Include a reverse layout feature to reverse the layout of a document when converting a left-to-right document to a right-to-left one or vice versa. Complex script rendering: InDesign supports Unicode character encoding, and Middle Eastern editions support complex text layouts for Arabic and Hebrew complex scripts. The underlying Arabic and Hebrew support is present in the Western editions of InDesign CS4, CS5, CS5.5, and CS6, but the user interface is not exposed, making it difficult to access.
Guideline execution engine
A guideline execution engine is a computer program which can interpret a clinical guideline represented in a computerized format and perform actions towards the user of an electronic medical record. A guideline execution engine needs to communicate with a host clinical information system. Virtual Medical Record (vMR) is one possible interface which can be used. The engine's main function is to manage instances of executed guidelines of individual patients. == Architecture == The following modules are generally needed for any engine: interface to clinical information system new guidelines loading module guideline interpreter module clinical events parser alert/recommendations dispatch == Guideline Interchange Format == The Guideline Interchange Format (GLIF) is a computer representation format for clinical guidelines. Represented guidelines can be executed using a guideline execution engine. The format has several versions as it has been improved. In 2003 GLIF3 was introduced. == Use of third party workflow engine as a guideline execution engine == Some commercial electronic health record systems use a workflow engine to execute clinical guidelines. RetroGuide and HealthFlow are examples of such an approach.