AI Headshot Apk

AI Headshot Apk — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

  • International Clinical Trials Registry Platform

    International Clinical Trials Registry Platform

    The International Clinical Trials Registry Platform (ICTRP) is a platform for the registration of clinical trials operated by the World Health Organization. The ICTRP combines data from multiple cooperating clinical trials registries to generate a global view of clinical trials worldwide, with a search portal that allows access to the entire dataset. It requires a minimum standard set of database fields, the WHO Trial Registration Data Set, to be present for a trial to be registered. All entries are given a Universal Trial Number (UTN) that identifies them uniquely. The organization has sought to assist various national governments in establishing their own clinical trials databases. It combines data from the following primary registries and data providers: Australian New Zealand Clinical Trials Registry (ANZCTR) Brazilian Clinical Trials Registry (ReBec) Chinese Clinical Trial Registry (ChiCTR) Clinical Research Information Service (CRiS), Republic of Korea ClinicalTrials.gov Clinical Trials Information System (CTIS), European Medicines Agency Clinical Trials Registry - India (CTRI) Cuban Public Registry of Clinical Trials (RPCEC) EU Clinical Trials Register (EU-CTR) German Clinical Trials Register (DRKS) Iranian Registry of Clinical Trials (IRCT) ISRCTN (UK) International Traditional Medicine Clinical Trial Registry (ITMCTR) Japan Registry of Clinical Trials (jRCT) Japan Primary Registries Network (JPRN) Lebanese Clinical Trials Registry (LBCTR) Overview of Medical Research in the Netherlands (OMON) Thai Clinical Trials Registry (TCTR) Pan African Clinical Trial Registry (PACTR) Peruvian Clinical Trial Registry (REPEC) Sri Lanka Clinical Trials Registry (SLCTR)

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  • ChromaDB

    ChromaDB

    Chroma or ChromaDB is open-source data infrastructure tailored to applications with large language models. Its headquarters are in San Francisco. In April 2023, it raised 18 million US dollars as seed funding. ChromaDB has been used in academic studies on artificial intelligence, particularly as part of the tech stack for retrieval-augmented generation.

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  • Natural language processing

    Natural language processing

    Natural language processing (NLP) is the processing of natural language information by a computer. NLP is a subfield of computer science and is closely associated with artificial intelligence. NLP is also related to information retrieval, knowledge representation, computational linguistics, and linguistics more broadly. Major processing tasks in an NLP system include: speech recognition, text classification, natural language understanding, and natural language generation. == History == Natural language processing has its roots in the 1950s. Already in 1950, Alan Turing published an article titled "Computing Machinery and Intelligence," which proposed what is now called the Turing test as a criterion of intelligence, though at the time that was not articulated as a problem separate from artificial intelligence. The proposed test includes a task that involves the automated interpretation and generation of natural language. === Symbolic NLP (1950s – early 1990s) === The premise of symbolic NLP is often illustrated using John Searle's Chinese room thought experiment: Given a collection of rules (e.g., a Chinese phrasebook, with questions and matching answers), the computer emulates natural language understanding (or other NLP tasks) by applying those rules to the data it confronts. 1950s: The Georgetown experiment in 1954 involved fully automatic translation of more than sixty Russian sentences into English. The authors claimed that within three or five years, machine translation would be a solved problem. However, real progress was much slower, and after the ALPAC report in 1966, which found that ten years of research had failed to fulfill the expectations, funding for machine translation was dramatically reduced. Little further research in machine translation was conducted in America (though some research continued elsewhere, such as Japan and Europe) until the late 1980s when the first statistical machine translation systems were developed. 1960s: Some notably successful natural language processing systems developed in the 1960s were SHRDLU, a natural language system working in restricted "blocks worlds" with restricted vocabularies, and ELIZA, a simulation of Rogerian psychotherapy, written by Joseph Weizenbaum between 1964 and 1966. Despite using minimal information about human thought or emotion, ELIZA was able to produce interactions that appeared human-like. When the "patient" exceeded the very small knowledge base, ELIZA might provide a generic response, for example, responding to "My head hurts" with "Why do you say your head hurts?". Ross Quillian's successful work on natural language was demonstrated with a vocabulary of only twenty words, because that was all that would fit in a computer memory at the time. 1970s: During the 1970s, many programmers began to write "conceptual ontologies", which structured real-world information into computer-understandable data. Examples are MARGIE (Schank, 1975), SAM (Cullingford, 1978), PAM (Wilensky, 1978), TaleSpin (Meehan, 1976), QUALM (Lehnert, 1977), Politics (Carbonell, 1979), and Plot Units (Lehnert 1981). During this time, the first chatterbots were written (e.g., PARRY). 1980s: The 1980s and early 1990s mark the heyday of symbolic methods in NLP. Focus areas of the time included research on rule-based parsing (e.g., the development of HPSG as a computational operationalization of generative grammar), morphology (e.g., two-level morphology), semantics (e.g., Lesk algorithm), reference (e.g., within Centering Theory) and other areas of natural language understanding (e.g., in the Rhetorical Structure Theory). Other lines of research were continued, e.g., the development of chatterbots with Racter and Jabberwacky. An important development (that eventually led to the statistical turn in the 1990s) was the rising importance of quantitative evaluation in this period. === Statistical NLP (1990s–present) === Up until the 1980s, most natural language processing systems were based on complex sets of hand-written rules. Starting in the late 1980s, however, there was a revolution in natural language processing with the introduction of machine learning algorithms for language processing. This shift was influenced by increasing computational power (see Moore's law) and a decline in the dominance of Chomskyan linguistic theories (e.g. transformational grammar), whose theoretical underpinnings discouraged the sort of corpus linguistics that underlies the machine-learning approach to language processing. 1990s: Many of the notable early successes in statistical methods in NLP occurred in the field of machine translation, due especially to work at IBM Research, such as IBM alignment models. These systems were able to take advantage of existing multilingual textual corpora that had been produced by the Parliament of Canada and the European Union as a result of laws calling for the translation of all governmental proceedings into all official languages of the corresponding systems of government. However, many systems relied on corpora that were specifically developed for the tasks they were designed to perform. This reliance has been a major limitation to their broader effectiveness and continues to affect similar systems. Consequently, significant research has focused on methods for learning effectively from limited amounts of data. 2000s: With the growth of the web, increasing amounts of raw (unannotated) language data have become available since the mid-1990s. Research has thus increasingly focused on unsupervised and semi-supervised learning algorithms. Such algorithms can learn from data that has not been hand-annotated with the desired answers or using a combination of annotated and non-annotated data. Generally, this task is much more difficult than supervised learning, and typically produces less accurate results for a given amount of input data. However, large quantities of non-annotated data are available (including, among other things, the entire content of the World Wide Web), which can often make up for the worse efficiency if the algorithm used has a low enough time complexity to be practical. 2003: word n-gram model, at the time the best statistical algorithm, is outperformed by a multi-layer perceptron (with a single hidden layer and context length of several words, trained on up to 14 million words, by Bengio et al.) 2010: Tomáš Mikolov (then a PhD student at Brno University of Technology) with co-authors applied a simple recurrent neural network with a single hidden layer to language modeling, and in the following years he went on to develop Word2vec. In the 2010s, representation learning and deep neural network-style (featuring many hidden layers) machine learning methods became widespread in natural language processing. This shift gained momentum due to results showing that such techniques can achieve state-of-the-art results in many natural language tasks, e.g., in language modeling and parsing. This is increasingly important in medicine and healthcare, where NLP helps analyze notes and text in electronic health records that would otherwise be inaccessible for study when seeking to improve care or protect patient privacy. == Approaches: Symbolic, statistical, neural networks == Symbolic approach, i.e., the hand-coding of a set of rules for manipulating symbols, coupled with a dictionary lookup, was historically the first approach used both by AI in general and by NLP in particular: such as by writing grammars or devising heuristic rules for stemming. Machine learning approaches, which include both statistical and neural networks, on the other hand, have many advantages over the symbolic approach: both statistical and neural network methods tend to focus more on the most common cases extracted from a corpus of texts, whereas the rule-based approach needs to provide rules for both rare and common cases equally. language models, produced by either statistical or neural networks methods, are more robust to both unfamiliar (e.g. containing words or structures that have not been seen before) and erroneous input (e.g. with misspelled words or words accidentally omitted) in comparison to the rule-based systems, which are also more costly to produce. the larger such a (probabilistic) language model is, the more accurate it becomes, in contrast to rule-based systems that can gain accuracy only by increasing the amount and complexity of the rules leading to intractability problems. Rule-based systems are commonly used: when the amount of training data is insufficient to successfully apply machine learning methods, e.g., for the machine translation of low-resource languages such as provided by the Apertium system, for preprocessing in NLP pipelines, e.g., tokenization, or for post-processing and transforming the output of NLP pipelines, e.g., for knowledge extraction from syntactic parses. === Statistical approach === In the late 1980s and mid-1990s, the statistical approach ended a peri

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  • Lenny (chatbot)

    Lenny (chatbot)

    Lenny is a chatbot designed to scam bait telemarketers, scammers, and other unwanted incoming calls using messages. == Background == Telemarketers may be perceived by some as annoying and wasting people's time, and some deliberately attempt to scam or defraud people. In April 2018, stats published by YouMail estimated the United States received over three billion robocalls that month. Attempts to block the callers have been hindered by Caller ID spoofing. == Features == The bot was written in 2011, and development taken over by an Alberta-based programmer known as "Mango" two years later. It is driven by sixteen pre-recorded audio clips, spoken in a soft and slow Australian accent in the manner of an elderly man. The bot's original creator stated on Reddit that in building the character he asked himself the question "What would be a telemarketer's worst nightmare?" He answered with this being a lonely old man who is up for a chat, proud of his family and can't focus on the telemarketer's goal. There is no speech recognition or artificial intelligence, and the bot's software is simple and straightforward. The first four clips are played sequentially in order to grab the telemarketer's interest and begin their sales pitch to Lenny, then the remaining twelve are played sequentially on loop until the telemarketer hangs up. The program waits for a gap of 1.5 seconds of silence before playing the next audio clip, to simulate natural breaks in the conversation. The messages are purposefully vague and open-ended so they can be applied to as many conversations as possible. They include references to Lenny's children, the state of the economy, and being interrupted by some ducks outside. According to research into the bot, around 75% of callers realise they are talking to a computer program within two minutes; however, some calls have lasted around an hour. == Distribution == Though other chatbots had been developed earlier, Lenny was the first one to be released for free on a public server and could be accessed by anyone. Recordings of conversations with the bot are widely shared online on websites such as Reddit and YouTube. Though "Mango" only intended Lenny to be used against dishonest telemarketers, such as scammers, he does not mind it being used against callers who are merely annoying. The bot has also been used against political campaigners, such as a supporter of Pierre Poilievre in the 2015 Canadian federal election.

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  • Hard sigmoid

    Hard sigmoid

    In artificial intelligence, especially computer vision and artificial neural networks, a hard sigmoid is non-smooth function used in place of a sigmoid function. These retain the basic shape of a sigmoid, rising from 0 to 1, but using simpler functions, especially piecewise linear functions or piecewise constant functions. These are preferred where speed of computation is more important than precision. == Examples == The most extreme examples are the sign function or Heaviside step function, which go from −1 to 1 or 0 to 1 (which to use depends on normalization) at 0. Other examples include the Theano library, which provides two approximations: ultra_fast_sigmoid, which is a multi-part piecewise approximation and hard_sigmoid, which is a 3-part piecewise linear approximation (output 0, line with slope 0.2, output 1).

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  • Example-based machine translation

    Example-based machine translation

    Example-based machine translation (EBMT) is a method of machine translation often characterized by its use of a bilingual corpus with parallel texts as its main knowledge base at run-time. It is essentially a translation by analogy and can be viewed as an implementation of a case-based reasoning approach to machine learning. == Translation by analogy == At the foundation of example-based machine translation is the idea of translation by analogy. When applied to the process of human translation, the idea that translation takes place by analogy is a rejection of the idea that people translate sentences by doing deep linguistic analysis. Instead, it is founded on the belief that people translate by first decomposing a sentence into certain phrases, then by translating these phrases, and finally by properly composing these fragments into one long sentence. Phrasal translations are translated by analogy to previous translations. The principle of translation by analogy is encoded to example-based machine translation through the example translations that are used to train such a system. Other approaches to machine translation, including statistical machine translation, also use bilingual corpora to learn the process of translation. == History == Example-based machine translation was first suggested by Makoto Nagao in 1984. He pointed out that it is especially adapted to translation between two totally different languages, such as English and Japanese. In this case, one sentence can be translated into several well-structured sentences in another language, therefore, it is no use to do the deep linguistic analysis characteristic of rule-based machine translation. == Example == Example-based machine translation systems are trained from bilingual parallel corpora containing sentence pairs like the example shown in the table above. Sentence pairs contain sentences in one language with their translations into another. The particular example shows an example of a minimal pair, meaning that the sentences vary by just one element. These sentences make it simple to learn translations of portions of a sentence. For example, an example-based machine translation system would learn three units of translation from the above example: How much is that X ? corresponds to Ano X wa ikura desu ka. red umbrella corresponds to akai kasa small camera corresponds to chiisai kamera Composing these units can be used to produce novel translations in the future. For example, if we have been trained using some text containing the sentences: President Kennedy was shot dead during the parade. and The convict escaped on July 15th., then we could translate the sentence The convict was shot dead during the parade. by substituting the appropriate parts of the sentences. == Phrasal verbs == Example-based machine translation is best suited for sub-language phenomena like phrasal verbs. Phrasal verbs have highly context-dependent meanings. They are common in English, where they comprise a verb followed by an adverb and/or a preposition, which are called the particle to the verb. Phrasal verbs produce specialized context-specific meanings that may not be derived from the meaning of the constituents. There is almost always an ambiguity during word-to-word translation from source to the target language. As an example, consider the phrasal verb "put on" and its Hindustani translation. It may be used in any of the following ways: Ram put on the lights. (Switched on) (Hindustani translation: Jalana) Ram put on a cap. (Wear) (Hindustani translation: Pahenna)

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  • Lexical substitution

    Lexical substitution

    Lexical substitution is the task of identifying a substitute for a word in the context of a clause. For instance, given the following text: "After the match, replace any remaining fluid deficit to prevent chronic dehydration throughout the tournament", a substitute of game might be given. Lexical substitution is strictly related to word sense disambiguation (WSD), in that both aim to determine the meaning of a word. However, while WSD consists of automatically assigning the appropriate sense from a fixed sense inventory, lexical substitution does not impose any constraint on which substitute to choose as the best representative for the word in context. By not prescribing the inventory, lexical substitution overcomes the issue of the granularity of sense distinctions and provides a level playing field for automatic systems that automatically acquire word senses (a task referred to as Word Sense Induction). == Evaluation == In order to evaluate automatic systems on lexical substitution, a task was organized at the Semeval-2007 evaluation competition held in Prague in 2007. A Semeval-2010 task on cross-lingual lexical substitution has also taken place. == Skip-gram model == The skip-gram model takes words with similar meanings into a vector space (collection of objects that can be added together and multiplied by numbers) that are found close to each other in N-dimensions (list of items). A variety of neural networks (computer system modeled after a human brain) are formed together as a result of the vectors and networks that are related together. This all occurs in the dimensions of the vocabulary that has been generated in a network. The model has been used in lexical substitution automation and prediction algorithms. One such algorithm developed by Oren Melamud, Omer Levy, and Ido Dagan uses the skip-gram model to find a vector for each word and its synonyms. Then, it calculates the cosine distance between vectors to determine which words will be the best substitutes. === Example === In a sentence like "The dog walked at a quick pace" each word has a specific vector in relation to the other. The vector for "The" would be [1,0,0,0,0,0,0] because the 1 is the word vocabulary and the 0s are the words surrounding that vocabulary, which create a vector.

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  • Ghana Post GPS

    Ghana Post GPS

    GhanaPostGPS is a web and smartphone application, sponsored by the government of Ghana and developed by Vokacom, to provide a digital addresses and postal codes for every 5 squared meter location in Ghana. The digital address is a composite of the postcode (region, district & area code) plus a unique address. GhanaPostGPS is the first digital addressing system created by the government of Ghana. GhanaPost GPS is a mandatory requirement for obtaining the National Identification Card and other services.

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  • Fabric computing

    Fabric computing

    Fabric computing or unified computing involves constructing a computing fabric consisting of interconnected nodes that look like a weave or a fabric when seen collectively from a distance. Usually the phrase refers to a consolidated high-performance computing system consisting of loosely coupled storage, networking and parallel processing functions linked by high bandwidth interconnects (such as 10 Gigabit Ethernet and InfiniBand) but the term has also been used to describe platforms such as the Azure Services Platform and grid computing in general (where the common theme is interconnected nodes that appear as a single logical unit). The fundamental components of fabrics are "nodes" (processor(s), memory, and/or peripherals) and "links" (functional connections between nodes). While the term "fabric" has also been used in association with storage area networks and with switched fabric networking, the introduction of compute resources provides a complete "unified" computing system. Other terms used to describe such fabrics include "unified fabric", "data center fabric" and "unified data center fabric". Ian Foster, director of the Computation Institute at the Argonne National Laboratory and University of Chicago suggested in 2007 that grid computing "fabrics" were "poised to become the underpinning for next-generation enterprise IT architectures and be used by a much greater part of many organizations". == History == While the term has been in use since the mid to late 1990s the growth of cloud computing and Cisco's evangelism of unified data center fabrics followed by unified computing (an evolutionary data center architecture whereby blade servers are integrated or unified with supporting network and storage infrastructure) starting March 2009 has renewed interest in the technology. There have been mixed reactions to Cisco's architecture, particularly from rivals who claim that these proprietary systems will lock out other vendors. Analysts claim that this "ambitious new direction" is "a big risk" as companies such as IBM and HP who have previously partnered with Cisco on data center projects (accounting for $2–3bn of Cisco's annual revenue) are now competing with them. In 2007, Wombat Financial Software launched the "Wombat Data Fabric," the first commercial off-the-shelf software platform providing high performance / low-latency RDMA-based messaging across an Infiniband switch. == Key characteristics == The main advantages of fabrics are that massive concurrent processing combined with a huge, tightly coupled address space makes it possible to solve huge computing problems (such as those presented by delivery of cloud computing services); and that they are both scalable and able to be dynamically reconfigured. Challenges include a non-linearly degrading performance curve, whereby adding resources does not linearly increase performance which is a common problem with parallel computing and maintaining security. == Companies == As of 2015 companies offering unified or fabric computing systems include Avaya, Brocade, Cisco, Dell, Egenera, HPE, IBM, Liquid Computing Corporation, TIBCO, Unisys, and Xsigo Systems.

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  • Xiaoice

    Xiaoice

    Xiaoice (Chinese: 微软小冰; pinyin: Wēiruǎn Xiǎobīng; lit. 'Microsoft Little Ice', IPA [wéɪɻwânɕjâʊpíŋ]) is an AI system developed by Microsoft (Asia) Software Technology Center (STCA) in 2014 based on an emotional computing framework. In July 2018, Microsoft Xiaoice released the 6th generation. Xiaoice Company, formerly known as AI Xiaoice Team of Microsoft Software Technology Center Asia, was Microsoft's largest independent R&D team for AI products. Founded in China in December 2013 with an expanded Japanese R&D team established in September 2014, this team is distributed in Beijing, Suzhou, and Tokyo, etc. with its technical products covering Asia. On 13 July 2020, Microsoft spun off its Xiaoice business into a separate company. As of 2021, the AI chatbots created and hosted by the Xiaoice framework accounted for about 60% of total global AI interactions. == Platforms, languages and countries == Xiaoice exists on more than 40 platforms in four countries (China, Japan, USA and Indonesia) including apps such as WeChat, QQ, Weibo and Meipai in China, and Facebook Messenger in USA and LINE in Japan. == Introduction == On 13 July 2020, Microsoft spun off its Xiaoice business into a separate company, aiming at enabling the Xiaoice product line to accelerate the pace of local innovation and commercialization, and appointed Dr. Harry Shum, former global executive VP of Microsoft, as the chairman of the new company, Li Di, Microsoft Partner of Products in Microsoft STCA, as the CEO, and Cliff, Chief R&D Director, as the GM of the Japan branch. The new company will continue to use the brands of Xiaoice China and Rinna Japan. As of 2022, the single brand of Xiaoice has covered 660 million online users, 1 billion third-party smart devices and 900 million content viewers in the aforementioned countries. Xiaoice's customers include China Merchants Group, Winter Sports Center of the General Administration of Sport of China, China Textile Information Center, China Unicom, China Foreign Exchange Trade System, Hong Kong Securities and Futures Commission (SFC), Wind Information, BMW, Nissan, SAIC Motor, BAIC Group, Nio Inc., XPeng, HiPhi, Vanke, Wensli, etc. The Xiaoice Avatar Framework has incubated tens of millions of AI Beings, such as Xiaoice, Rinna, the Expo exhibitor Xia Yubing, the singer He Chang, the anchor F201, the human observer MERROR, anime robot character Roboko, and other; == Application == === Poet === In May 2017, the first AI-authored collection of poems in China—The Sunshine Lost Windows was published by Xiaoice. === Singer === Xiaoice has released dozens of songs with the similar quality to human singers, including I Know I New, Breeze, I Am Xiaoice, Miss You etc. The 4th version of the DNN singing model allows Xiaoice to learn more details. For example, Xiaoice can produce this breathing sound along with her singing as human. === Kid audio-books reciter === Xiaoice can automatically analyze the stories, to choose the suitable tones and characters to finish the entire process of creating the audio. === Designer === By learning the melodies of the songs and the landmarks about different cities, Xiaoice can create visual artworks of skylines when listening to the songs related to this city. Skyline Series T-shirts designed by Xiaoice have been jointly launched with SELECTED and been sold in stores. === TV and radio hostess === Xiaoice has hosted 21 TV programs and 28 Radio programs, such as CCTV-1 AI Show, Dragon TV Morning East News, Hunan TV My Future, several daily radio programs for Jiangsu FM99.7, Hunan FM89.3, Henan FM104.1 etc. === "AI being" === An "AI being" is a concept proposed by the Xiaoice team in 2019. According to the "White Book of China Virtual Human Development Industry in 2022" released by Frost & Sullivan and LeadLeo, the white paper cites six elements of an AI being proposed by the Xiaoice team, including: Persona, Attitude, Biological Characteristic, Creation, Knowledge and Skill. On May 16, 2023, Xiaoice released their "GPT Clones" as its "GPT Human Cloning Plan." The program is aimed at replicating celebrities, public figures, and regular people. As of June 2023, Xiaoice had launched more than 300 "GPT Clones." People were invited to register via WeChat in China and Japan. A major point of focus for Xiaoice with their AI Beings is having virtual partners. A paid fee allow for more complex responses, voice messages, and more. == Community feedback == Bill Gates mentioned Xiaoice during his speech at the Peking University: "Some of you may have had conversations with Xiaoice on Weibo, or seen her weather forecasts on TV, or read her column in the Qianjiang Evening News." '"Xiaoice has attracted 45 million followers and is quite skilled at multitasking. And I’ve heard she’s gotten good enough at sensing a user’s emotional state that she can even help with relationship breakups." According to Mr Li Di, vice President of Microsoft (Asia) Internet Engineering School, Xiaoice started writing poems since last year. Based on the data base that includes works of 519 Chinese contemporary poets since 1920s, a 100 hour long training session was conducted to allow Xiaoice to acquire the ability to write poems. What is more impressive is that Xiaoice has never been spotted as a bot while publishing poems on various forums and traditional literary under an alias. == Controversy == In 2017, Xiaoice was taken offline on WeChat after giving user responses critical to the Chinese government. It was subsequently censored and the bots will avoid and sidestep any inquiries using politically sensitive terms and phrases. == Activity == On September 22, 2021, Xiaoice Company and Microsoft Software Technology Center Asia (STCA) jointly held the 9th generation Xiaoice annual press conference in Beijing.Upgrading of Core Technologies of the 9th Generation Xiaoice Avatar Framework,1st First-party Social Platform APP "Xiaoice Island" from Xiaoice, WeChat Xiaoice has been reopened and other information == Regional varieties of Xiaoice == China: Xiaoice, launched in 2014 Japan: りんな, launched in 2015 America: Zo, launched in 2016 – discontinued summer 2019 India: Ruuh, launched in 2017 – discontinued June 21, 2019 Indonesia: Rinna, launched in 2017

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  • Deep learning in photoacoustic imaging

    Deep learning in photoacoustic imaging

    Photoacoustic imaging (PA) is based on the photoacoustic effect, in which optical absorption causes a rise in temperature, which causes a subsequent rise in pressure via thermo-elastic expansion. This pressure rise propagates through the tissue and is sensed via ultrasonic transducers. Due to the proportionality between the optical absorption, the rise in temperature, and the rise in pressure, the ultrasound pressure wave signal can be used to quantify the original optical energy deposition within the tissue. Photoacoustic imaging has applications of deep learning in both photoacoustic computed tomography (PACT) and photoacoustic microscopy (PAM). PACT utilizes wide-field optical excitation and an array of unfocused ultrasound transducers. Similar to other computed tomography methods, the sample is imaged at multiple view angles, which are then used to perform an inverse reconstruction algorithm based on the detection geometry (typically through universal backprojection, modified delay-and-sum, or time reversal ) to elicit the initial pressure distribution within the tissue. PAM on the other hand uses focused ultrasound detection combined with weakly focused optical excitation (acoustic resolution PAM or AR-PAM) or tightly focused optical excitation (optical resolution PAM or OR-PAM). PAM typically captures images point-by-point via a mechanical raster scanning pattern. At each scanned point, the acoustic time-of-flight provides axial resolution while the acoustic focusing yields lateral resolution. == Applications of deep learning in PACT == The first application of deep learning in PACT was by Reiter et al. in which a deep neural network was trained to learn spatial impulse responses and locate photoacoustic point sources. The resulting mean axial and lateral point location errors on 2,412 of their randomly selected test images were 0.28 mm and 0.37 mm respectively. After this initial implementation, the applications of deep learning in PACT have branched out primarily into removing artifacts from acoustic reflections, sparse sampling, limited-view, and limited-bandwidth. There has also been some recent work in PACT toward using deep learning for wavefront localization. There have been networks based on fusion of information from two different reconstructions to improve the reconstruction using deep learning fusion based networks. === Using deep learning to locate photoacoustic point sources === Traditional photoacoustic beamforming techniques modeled photoacoustic wave propagation by using detector array geometry and the time-of-flight to account for differences in the PA signal arrival time. However, this technique failed to account for reverberant acoustic signals caused by acoustic reflection, resulting in acoustic reflection artifacts that corrupt the true photoacoustic point source location information. In Reiter et al., a convolutional neural network (similar to a simple VGG-16 style architecture) was used that took pre-beamformed photoacoustic data as input and outputted a classification result specifying the 2-D point source location. ==== Deep learning for PA wavefront localization ==== Johnstonbaugh et al. was able to localize the source of photoacoustic wavefronts with a deep neural network. The network used was an encoder-decoder style convolutional neural network. The encoder-decoder network was made of residual convolution, upsampling, and high field-of-view convolution modules. A Nyquist convolution layer and differentiable spatial-to-numerical transform layer were also used within the architecture. Simulated PA wavefronts served as the input for training the model. To create the wavefronts, the forward simulation of light propagation was done with the NIRFast toolbox and the light-diffusion approximation, while the forward simulation of sound propagation was done with the K-Wave toolbox. The simulated wavefronts were subjected to different scattering mediums and Gaussian noise. The output for the network was an artifact free heat map of the targets axial and lateral position. The network had a mean error rate of less than 30 microns when localizing target below 40 mm and had a mean error rate of 1.06 mm for localizing targets between 40 mm and 60 mm. With a slight modification to the network, the model was able to accommodate multi target localization. A validation experiment was performed in which pencil lead was submerged into an intralipid solution at a depth of 32 mm. The network was able to localize the lead's position when the solution had a reduced scattering coefficient of 0, 5, 10, and 15 cm−1. The results of the network show improvements over standard delay-and-sum or frequency-domain beamforming algorithms and Johnstonbaugh proposes that this technology could be used for optical wavefront shaping, circulating melanoma cell detection, and real-time vascular surgeries. === Removing acoustic reflection artifacts (in the presence of multiple sources and channel noise) === Building on the work of Reiter et al., Allman et al. utilized a full VGG-16 architecture to locate point sources and remove reflection artifacts within raw photoacoustic channel data (in the presence of multiple sources and channel noise). This utilization of deep learning trained on simulated data produced in the MATLAB k-wave library, and then later reaffirmed their results on experimental data. === Ill-posed PACT reconstruction === In PACT, tomographic reconstruction is performed, in which the projections from multiple solid angles are combined to form an image. When reconstruction methods like filtered backprojection or time reversal, are ill-posed inverse problems due to sampling under the Nyquist-Shannon's sampling requirement or with limited-bandwidth/view, the resulting reconstruction contains image artifacts. Traditionally these artifacts were removed with slow iterative methods like total variation minimization, but the advent of deep learning approaches has opened a new avenue that utilizes a priori knowledge from network training to remove artifacts. In the deep learning methods that seek to remove these sparse sampling, limited-bandwidth, and limited-view artifacts, the typical workflow involves first performing the ill-posed reconstruction technique to transform the pre-beamformed data into a 2-D representation of the initial pressure distribution that contains artifacts. Then, a convolutional neural network (CNN) is trained to remove the artifacts, in order to produce an artifact-free representation of the ground truth initial pressure distribution. ==== Using deep learning to remove sparse sampling artifacts ==== When the density of uniform tomographic view angles is under what is prescribed by the Nyquist-Shannon's sampling theorem, it is said that the imaging system is performing sparse sampling. Sparse sampling typically occurs as a way of keeping production costs low and improving image acquisition speed. The typical network architectures used to remove these sparse sampling artifacts are U-net and Fully Dense (FD) U-net. Both of these architectures contain a compression and decompression phase. The compression phase learns to compress the image to a latent representation that lacks the imaging artifacts and other details. The decompression phase then combines with information passed by the residual connections in order to add back image details without adding in the details associated with the artifacts. FD U-net modifies the original U-net architecture by including dense blocks that allow layers to utilize information learned by previous layers within the dense block. Another technique was proposed using a simple CNN based architecture for removal of artifacts and improving the k-wave image reconstruction. ==== Removing limited-view artifacts with deep learning ==== When a region of partial solid angles are not captured, generally due to geometric limitations, the image acquisition is said to have limited-view. As illustrated by the experiments of Davoudi et al., limited-view corruptions can be directly observed as missing information in the frequency domain of the reconstructed image. Limited-view, similar to sparse sampling, makes the initial reconstruction algorithm ill-posed. Prior to deep learning, the limited-view problem was addressed with complex hardware such as acoustic deflectors and full ring-shaped transducer arrays, as well as solutions like compressed sensing, weighted factor, and iterative filtered backprojection. The result of this ill-posed reconstruction is imaging artifacts that can be removed by CNNs. The deep learning algorithms used to remove limited-view artifacts include U-net and FD U-net, as well as generative adversarial networks (GANs) and volumetric versions of U-net. One GAN implementation of note improved upon U-net by using U-net as a generator and VGG as a discriminator, with the Wasserstein metric and gradient penalty to stabilize training (WGAN-GP). ==== Pixel-wise interpolation

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  • Neighborhood operation

    Neighborhood operation

    In computer vision and image processing a neighborhood operation is a commonly used class of computations on image data which implies that it is processed according to the following pseudo code: Visit each point p in the image data and do { N = a neighborhood or region of the image data around the point p result(p) = f(N) } This general procedure can be applied to image data of arbitrary dimensionality. Also, the image data on which the operation is applied does not have to be defined in terms of intensity or color, it can be any type of information which is organized as a function of spatial (and possibly temporal) variables in p. The result of applying a neighborhood operation on an image is again something which can be interpreted as an image, it has the same dimension as the original data. The value at each image point, however, does not have to be directly related to intensity or color. Instead it is an element in the range of the function f, which can be of arbitrary type. Normally the neighborhood N is of fixed size and is a square (or a cube, depending on the dimensionality of the image data) centered on the point p. Also the function f is fixed, but may in some cases have parameters which can vary with p, see below. In the simplest case, the neighborhood N may be only a single point. This type of operation is often referred to as a point-wise operation. == Examples == The most common examples of a neighborhood operation use a fixed function f which in addition is linear, that is, the computation consists of a linear shift invariant operation. In this case, the neighborhood operation corresponds to the convolution operation. A typical example is convolution with a low-pass filter, where the result can be interpreted in terms of local averages of the image data around each image point. Other examples are computation of local derivatives of the image data. It is also rather common to use a fixed but non-linear function f. This includes median filtering, and computation of local variances. The Nagao-Matsuyama filter is an example of a complex local neighbourhood operation that uses variance as an indicator of the uniformity within a pixel group. The result is similar to a convolution with a low-pass filter with the added effect of preserving sharp edges. There is also a class of neighborhood operations in which the function f has additional parameters which can vary with p: Visit each point p in the image data and do { N = a neighborhood or region of the image data around the point p result(p) = f(N, parameters(p)) } This implies that the result is not shift invariant. Examples are adaptive Wiener filters. == Implementation aspects == The pseudo code given above suggests that a neighborhood operation is implemented in terms of an outer loop over all image points. However, since the results are independent, the image points can be visited in arbitrary order, or can even be processed in parallel. Furthermore, in the case of linear shift-invariant operations, the computation of f at each point implies a summation of products between the image data and the filter coefficients. The implementation of this neighborhood operation can then be made by having the summation loop outside the loop over all image points. An important issue related to neighborhood operation is how to deal with the fact that the neighborhood N becomes more or less undefined for points p close to the edge or border of the image data. Several strategies have been proposed: Compute result only for points p for which the corresponding neighborhood is well-defined. This implies that the output image will be somewhat smaller than the input image. Zero padding: Extend the input image sufficiently by adding extra points outside the original image which are set to zero. The loops over the image points described above visit only the original image points. Border extension: Extend the input image sufficiently by adding extra points outside the original image which are set to the image value at the closest image point. The loops over the image points described above visit only the original image points. Mirror extension: Extend the image sufficiently much by mirroring the image at the image boundaries. This method is less sensitive to local variations at the image boundary than border extension. Wrapping: The image is tiled, so that going off one edge wraps around to the opposite side of the image. This method assumes that the image is largely homogeneous, for example a stochastic image texture without large textons.

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  • The Future of Work and Death

    The Future of Work and Death

    The Future of Work and Death is a 2016 documentary by Sean Blacknell and Wayne Walsh about the exponential growth of technology. The film showed at several film festivals including Raindance Film Festival, International Film Festival Rotterdam, Academia Film Olomouc and CPH:DOX. In May 2017 it received an official screening at the European Commission. It was distributed by First Run Features and Journeyman Pictures and was released on iTunes, Amazon Prime and On-demand on 9 May 2017. The film was made available on Sundance Now on 27 November 2017. A companion piece to the film, The Cost of Living, a documentary concerning universal basic income in Britain, was released on Amazon Prime on 8 October 2020. == Synopsis == World experts in the fields of futurology, anthropology, neuroscience, and philosophy consider the impact of technological advances on the two 'certainties' of human life; work and death. Charting human developments from Homo habilis, past the Industrial Revolution, to the digital age and beyond, the film looks at the shocking exponential rate at which mankind has managed to create technologies to ease the process of living. As we embark on the next phase of our adaptation, with automation and artificial intelligence signifying the complete move from man to machine, the film asks what the implications are for human fulfilment in an approaching era of job obsolescence and extreme longevity. == Cast == Dudley Sutton – Narrator Aubrey de Grey – Biomedical gerontologist and CSO of the SENS Research Foundation Will Self – Writer, journalist, political commentator and Professor of Contemporary Thought at Brunel University Rudolph E. Tanzi – Professor of Neurology at Harvard University and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH) Martin Ford – Futurist and author Steve Fuller – Auguste Comte Chair in Social Epistemology at the Department of sociology at University of Warwick Murray Shanahan – Professor of Cognitive Robotics at Imperial College London Gray Scott – Futurist, executive producer of this production Vivek Wadhwa – Entrepreneur, academic and Director of Research at the Center for Entrepreneurship and Research Commercialization at the Pratt School of Engineering, Duke University Zoltan Istvan – Transhumanist and journalist Joanna Cook – Anthropologist, University College London Nicholas Kamara – Physician, Kable Hospital David Pearce – Transhumanist philosopher and co-founder of Humanity+ Peter Cochrane – Futurist and entrepreneur John Harris – Bioethicist, philosopher and Director of the Institute for Science, Ethics and Innovation at the University of Manchester Riva Melissa-Tez – Entrepreneur and transhumanist Ian Pearson – Futurologist Stuart Armstrong – Artificial intelligence researcher at Future of Humanity Institute

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  • Semantic space

    Semantic space

    Semantic spaces in the natural language domain aim to create representations of natural language that are capable of capturing meaning. The original motivation for semantic spaces stems from two core challenges of natural language: Vocabulary mismatch (the fact that the same meaning can be expressed in many ways) and ambiguity of natural language (the fact that the same term can have several meanings). The application of semantic spaces in natural language processing (NLP) aims at overcoming limitations of rule-based or model-based approaches operating on the keyword level. The main drawback with these approaches is their brittleness, and the large manual effort required to create either rule-based NLP systems or training corpora for model learning. Rule-based and machine learning based models are fixed on the keyword level and break down if the vocabulary differs from that defined in the rules or from the training material used for the statistical models. Research in semantic spaces dates back more than 20 years. In 1996, two papers were published that raised a lot of attention around the general idea of creating semantic spaces: latent semantic analysis and Hyperspace Analogue to Language. However, their adoption was limited by the large computational effort required to construct and use those semantic spaces. A breakthrough with regard to the accuracy of modelling associative relations between words (e.g. "spider-web", "lighter-cigarette", as opposed to synonymous relations such as "whale-dolphin", "astronaut-driver") was achieved by explicit semantic analysis (ESA) in 2007. ESA was a novel (non-machine learning) based approach that represented words in the form of vectors with 100,000 dimensions (where each dimension represents an Article in Wikipedia). However practical applications of the approach are limited due to the large number of required dimensions in the vectors. More recently, advances in neural network techniques in combination with other new approaches (tensors) led to a host of new recent developments: Word2vec from Google, GloVe from Stanford University, and fastText from Facebook AI Research (FAIR) labs.

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  • Image registration

    Image registration

    Image registration is the process of transforming different sets of data into one coordinate system. Data may be multiple photographs, data from different sensors, times, depths, or viewpoints. It is used in computer vision, medical imaging, military automatic target recognition, and compiling and analyzing images and data from satellites. Registration is necessary in order to be able to compare or integrate the data obtained from these different measurements. == Algorithm classification == === Intensity-based vs feature-based === Image registration or image alignment algorithms can be classified into intensity-based and feature-based. One of the images is referred to as the target, fixed or sensed image and the others are referred to as the moving or source images. Image registration involves spatially transforming the source/moving image(s) to align with the target image. The reference frame in the target image is stationary, while the other datasets are transformed to match to the target. Intensity-based methods compare intensity patterns in images via correlation metrics, while feature-based methods find correspondence between image features such as points, lines, and contours. Intensity-based methods register entire images or sub-images. If sub-images are registered, centers of corresponding sub images are treated as corresponding feature points. Feature-based methods establish a correspondence between a number of especially distinct points in images. Knowing the correspondence between a number of points in images, a geometrical transformation is then determined to map the target image to the reference images, thereby establishing point-by-point correspondence between the reference and target images. Methods combining intensity-based and feature-based information have also been developed. === Transformation models === Image registration algorithms can also be classified according to the transformation models they use to relate the target image space to the reference image space. The first broad category of transformation models includes affine transformations, which include rotation, scaling, translation and shearing. Affine transformations are global in nature, thus, they cannot model local geometric differences between images. The second category of transformations allow 'elastic' or 'nonrigid' transformations. These transformations are capable of locally warping the target image to align with the reference image. Nonrigid transformations include radial basis functions (thin-plate or surface splines, multiquadrics, and compactly-supported transformations), physical continuum models (viscous fluids), and large deformation models (diffeomorphisms). Transformations are commonly described by a parametrization, where the model dictates the number of parameters. For instance, the translation of a full image can be described by a translation vector parameter. These models are called parametric models. Non-parametric models on the other hand, do not follow any parameterization, allowing each image element to be displaced arbitrarily. There are a number of programs that implement both estimation and application of a warp-field. It is a part of the SPM and AIR programs. === Transformations of coordinates via the law of function composition rather than addition === Alternatively, many advanced methods for spatial normalization are building on structure preserving transformations homeomorphisms and diffeomorphisms since they carry smooth submanifolds smoothly during transformation. Diffeomorphisms are generated in the modern field of Computational Anatomy based on flows since diffeomorphisms are not additive although they form a group, but a group under the law of function composition. For this reason, flows which generalize the ideas of additive groups allow for generating large deformations that preserve topology, providing 1-1 and onto transformations. Computational methods for generating such transformation are often called LDDMM which provide flows of diffeomorphisms as the main computational tool for connecting coordinate systems corresponding to the geodesic flows of Computational Anatomy. There are a number of programs which generate diffeomorphic transformations of coordinates via diffeomorphic mapping including MRI Studio and MRI Cloud.org === Spatial vs frequency domain methods === Spatial methods operate in the image domain, matching intensity patterns or features in images. Some of the feature matching algorithms are outgrowths of traditional techniques for performing manual image registration, in which an operator chooses corresponding control points (CP) in images. When the number of control points exceeds the minimum required to define the appropriate transformation model, iterative algorithms like RANSAC can be used to robustly estimate the parameters of a particular transformation type (e.g. affine) for registration of the images. Frequency-domain methods find the transformation parameters for registration of the images while working in the transform domain. Such methods work for simple transformations, such as translation, rotation, and scaling. Applying the phase correlation method to a pair of images produces a third image which contains a single peak. The location of this peak corresponds to the relative translation between the images. Unlike many spatial-domain algorithms, the phase correlation method is resilient to noise, occlusions, and other defects typical of medical or satellite images. Additionally, the phase correlation uses the fast Fourier transform to compute the cross-correlation between the two images, generally resulting in large performance gains. The method can be extended to determine rotation and scaling differences between two images by first converting the images to log-polar coordinates. Due to properties of the Fourier transform, the rotation and scaling parameters can be determined in a manner invariant to translation. === Single- vs multi-modality methods === Another classification can be made between single-modality and multi-modality methods. Single-modality methods tend to register images in the same modality acquired by the same scanner/sensor type, while multi-modality registration methods tended to register images acquired by different scanner/sensor types. Multi-modality registration methods are often used in medical imaging as images of a subject are frequently obtained from different scanners. Examples include registration of brain CT/MRI images or whole body PET/CT images for tumor localization, registration of contrast-enhanced CT images against non-contrast-enhanced CT images for segmentation of specific parts of the anatomy, and registration of ultrasound and CT images for prostate localization in radiotherapy. === Automatic vs interactive methods === Registration methods may be classified based on the level of automation they provide. Manual, interactive, semi-automatic, and automatic methods have been developed. Manual methods provide tools to align the images manually. Interactive methods reduce user bias by performing certain key operations automatically while still relying on the user to guide the registration. Semi-automatic methods perform more of the registration steps automatically but depend on the user to verify the correctness of a registration. Automatic methods do not allow any user interaction and perform all registration steps automatically. === Similarity measures for image registration === Image similarities are broadly used in medical imaging. An image similarity measure quantifies the degree of similarity between intensity patterns in two images. The choice of an image similarity measure depends on the modality of the images to be registered. Common examples of image similarity measures include cross-correlation, mutual information, sum of squared intensity differences, and ratio image uniformity. Mutual information and normalized mutual information are the most popular image similarity measures for registration of multimodality images. Cross-correlation, sum of squared intensity differences and ratio image uniformity are commonly used for registration of images in the same modality. Many new features have been derived for cost functions based on matching methods via large deformations have emerged in the field Computational Anatomy including Measure matching which are pointsets or landmarks without correspondence, Curve matching and Surface matching via mathematical currents and varifolds. == Uncertainty == There is a level of uncertainty associated with registering images that have any spatio-temporal differences. A confident registration with a measure of uncertainty is critical for many change detection applications such as medical diagnostics. In remote sensing applications where a digital image pixel may represent several kilometers of spatial distance (such as NASA's LANDSAT imagery), an uncertain image registration can mean that a solution could b

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