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  • Afghan Girls Robotics Team

    Afghan Girls Robotics Team

    The Afghan Girls Robotics Team, also known as the Afghan Dreamers, is an all-girl robotics team from Herat, Afghanistan, founded through the Digital Citizen Fund (DCF) in 2017 by Roya Mahboob and Alireza Mehraban. It is made up of girls between ages 12 and 18 and their mentors. Several members of the team were relocated to Qatar and Mexico by humanitarian and tech entrepreneur Sarah Porter following the fall of Kabul in August 2021. A documentary film featuring members of the team, titled Afghan Dreamers, was released by MTV Documentary Films in 2023. == Origins == The Afghan Girls Robotics Team was co-founded in 2017 by Roya Mahboob, who is their coach, mentor and sponsor, and founder of the Digital Citizen Fund (DCF), which is the parent organization for the team. Dean Kamen was planning a 2017 competition in the United States and had recruited Mahboob to form a team from Afghanistan. Out of 150 girls, 12 were selected for the first team. Before parts were sent by Kamen, they trained in the basement of the home of Mahboob's parents, with scrap metal and without safety equipment under the guidance of their coach, Mahboob's brother Alireza Mehraban, who is also a co-founder of the team. == 2017 and 2018 == In 2017, six members of the Afghan Girls Robotics Team traveled to the United States to participate in the international FIRST Global Challenge robotics competition. Their visas were rejected twice after they made two journeys from Herat to Kabul through Taliban-controlled areas, before officials in the United States government intervened to allow them to enter the United States. Customs officials also detained their robotics kits, which left them two weeks to construct their robot, unlike some teams that had more time. They were awarded a Silver medal for Courageous Achievement. One week after they returned home from the competition, the father of team captain Fatemah Qaderyan, Mohammad Asif Qaderyan, was killed in a suicide bombing. After their United States visas expired, the team participated in competitions in Estonia and Istanbul. Three of the 12 members participated in the 2017 Entrepreneurial Challenge at the Robotex festival in Estonia, and won the competition for their solar-powered robot designed to assist farmers. In 2018, the team trained in Canada, continued to travel in the United States for months and participate in competitions. == 2019 == The Afghan Girls Robotics team had aspirations to develop a science and technology school for girls in Afghanistan. Roya Mahboob interfaced with the School of Engineering and Applied Sciences (SEAS), the School of Architecture, and the Whitney and Betty MacMillan Center for International and Area Studies Yale University to design the infrastructure for what they named The Dreamer Institute. == 2020 == In March 2020, the governor of Herat at the time, in response to the COVID-19 pandemic in Afghanistan and a scarcity of ventilators, sought help with the design of low-cost ventilators, and the Afghan Girls Robotics Team was one of six teams contacted by the government. Using a design from Massachusetts Institute of Technology and with guidance from MIT engineers and Douglas Chin, a surgeon in California, the team developed a prototype with Toyota Corolla parts and a chain drive from a Honda motorcycle. UNICEF also supported the team with the acquisition of necessary parts during the three months they spent building the prototype that was completed in July 2020. Their design costs around $500 compared to $50,000 for a ventilator. In December 2020, Minister of Industry and Commerce Nizar Ahmad Ghoryani donated funding and obtained land for a factory to produce the ventilators. Under the direction of their mentor Roya Mahboob, the Afghan Dreamers also designed a UVC Robot for sanitization, and a Spray Robot for disinfection, both of which were approved by the Ministry of Health for production. == 2021 == In early August 2021, Somaya Faruqi, former captain of the team, was quoted by Public Radio International about the future of Afghanistan, stating, "We don’t support any group over another but for us what’s important is that we be able to continue our work. Women in Afghanistan have made a lot of progress over the past two decades and this progress must be respected." On August 17, 2021, the Afghan Girls Robotics Team and their coaches were reported to be attempting to evacuate, but unable to obtain a flight out of Afghanistan, and a lawyer appealed to Canada for assistance regarding the evacuation of the team members. As of August 19, 2021, nine members of the team and their coaches had evacuated to Qatar. The founder of the team, Roya Mahboob, and DCF board member, Elizabeth Schaeffer Brown, were previously in contact with the Qatari government to assist the team members in their evacuation from Afghanistan. By August 25, 2021, some members arrived in Mexico. Saghar, a team member who evacuated to Mexico, said, "We wanted to continue the path that we started to continue to go for our achievements and to go for having our dreams through reality. So that's why we decided to leave Afghanistan and go for somewhere safe" in an interview with The Associated Press. The members who have left Afghanistan participated in an online robotics competition in September and plan to continue their education. A documentary film titled Afghan Dreamers, produced by Beth Murphy and directed by David Greenwald, was in post-production when the team began to evacuate. == 2022 == The Afghan Dreamers were involved in a training program at the Texas A&M University at Qatar’s STEM Hub. == 2023 == The Afghan Girls Robotics Team had a booth at the 5th UN Conference on the Least Developed Countries, where they displayed some of the robots the team had constructed. == Afghan Dreamers documentary == The Afghan Dreamers documentary from MTV Documentary Films premiered in May 2023 on Paramount+. The film was directed by David Greenwald and produced by David Cowan and Beth Murphy. In a review for Screen Daily, Wendy Ide wrote, "This film, with its likeable cast of girl nerds and positive message, should enjoy a warm reception on the festival circuit, and will be of particular interest to events seeking to showcase women's stories from around the world. It also serves as a timely cautionary tale – a case study on just how quickly the rights and the opportunities of women can be curtailed, at the behest of the men in power." == Honors and awards == 2017 Silver medal for Courageous Achievement at the FIRST Global Challenge, science and technology 2017 Benefiting Humanity in AI Award at World Summit AI 2017 Winner, Entrepreneurship Challenge at Robotex in Estonia 2018 Permission to Dream Award, Raw Film Festival 2018 Conrad Innovation Challenge, Raw Film Festival 2018 Rookie All Star – District Championship, Canada 2018 Asia Game Changer Award Honoree 2019 Inspiring in Engineering Award – FIRST Detroit World Championship 2019 Asia Game Changer Award of California 2019 Safety Award – FIRST Global, Dubai 2021 Forbes 30 Under 30 Asia 2022 World Championships, Genoa, Switzerland

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  • Limnu

    Limnu

    Limnu was an online whiteboarding app founded in 2015 by David DeBry and David Hart. It allowed users to draw on virtual whiteboards and invite others by e-mail or by sharing a link. Invitees see any changes to the board in real time and, if allowed by the owner of the board, can also draw on the board. The service was accessible through a web application in desktop and mobile web browsers, as well as through an iOS application. It was headquartered in San Mateo, California. == History == In 2018, ZipSocket, a maker of online meeting software acquired Limnu. == Staff Directory == Andrew Kunz - CEO & Founder of ZipSocket Jenny Rice - Product Manager Max Requenes - Software Engineer Henry Maguire - Machine Learning Engineer

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  • Pocket (service)

    Pocket (service)

    Pocket, formerly known as Read It Later, was a social bookmarking service for storing, sharing and discovering web bookmarks, first released in 2007. Mozilla, the developer of Pocket, announced in May 2025 that it was discontinuing the service and would shut it down in July of that year. == History == Pocket was introduced in August 2007 as a Mozilla Firefox browser extension named Read It Later by Nathan (Nate) Weiner. Once his product was used by millions of people, he moved his office to Silicon Valley and four other people joined the Read It Later team. Weiner's intention was for the application to be like a TiVo directory for web content and to give users access to that content on any device. Read It Later obtained venture capital investments of US$2.5 million in 2011 and $5.0 million in 2012. The 2011 funding came from Foundation Capital, Baseline Ventures, Google Ventures, Founder Collective and unnamed angel investors. The company rejected an acquisition offer by Evernote after showing concerns that Evernote intended to shut down the Read It Later service and amalgamate its functionality into Evernote's main service. Initially, the Read It Later app was available in a free version and a paid version that included additional features. After the rebranding to Pocket, all paid features were made available in a free and advertisement-free app. In May 2014, a paid subscription service called Pocket Premium was introduced, adding server-side storage of articles and more powerful search tools. In June 2015, Pocket was included in Firefox, via a toolbar button and link to a user's Pocket list in the bookmark's menu. The integration was controversial, as users displayed concerns for the direct integration of a proprietary service into an open source application, and that it could not be completely disabled without editing advanced settings, unlike other third-party extensions. A Mozilla spokesperson stated that the feature was meant to leverage the service's popularity among Firefox users and clarified that all code related to the integration was open source. The spokesperson added that "[Mozilla had] gotten lots of positive feedback about the integration from users". On February 27, 2017, Pocket announced that it had been acquired by Mozilla Corporation, the commercial arm of Firefox's non-profit development group. Mozilla staff stated that Pocket would continue to operate as an independent subsidiary but that it would be leveraged as part of an ongoing "Context Graph" project. There were plans to open-source the server-side code of Pocket, though only parts of the project had been open-sourced as of 2024. On May 22, 2025, Mozilla announced that it would shut down Pocket on July 8, 2025. Exports of user data would be available until October 8, 2025, when accounts would be deleted. The email newsletter Pocket Hits was rebranded as Ten Tabs on June 12 as part of the closure, with it being changed to release only on weekdays. == Functions == The application allows the user to save an article or web page to remote servers for later reading. The article is sent to the user's Pocket list (synced to all of their devices) for offline reading. Pocket makes the article more readable by removing clutter and enabling the user to add tags and adjust text settings. == User base == The application had 17 million users and 1 billion saves, as of September 2015. Pocket was listed among Time magazine's 50 Best Android Applications for 2013. == Reception == Kent German of CNET said that "Read It Later is oh so incredibly useful for saving all the articles and news stories I find while commuting or waiting in line." Erez Zukerman of PC World said that supporting the developer is enough reason to buy what he deemed a "handy app". Bill Barol of Forbes said that although Read It Later works less well than Instapaper, "it makes my beloved Instapaper look and feel a little stodgy." In 2015, Pocket was awarded a Material Design Award for Adaptive Layout by Google for their Android application.

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  • WikiTok

    WikiTok

    WikiTok is a web application that shows random Wikipedia articles in an infinite scrolling format similar to TikTok. Created by New York-based civil and software engineer Isaac Gemal in February 2025, the application aims to provide an "anti-algorithmic" alternative to traditional social media platforms while combating doomscrolling. == Development == WikiTok was developed on February 3, 2025, after Gemal saw a viral tweet from developer Tyler Angert proposing "all of wikipedia on a single, scrollable page". Gemal created the initial prototype in approximately two hours, using the Claude LLM and Cursor coding editor, completing it by 2 a.m. that same night. The application was built with React 18, TypeScript, Tailwind CSS, and Vite, consisting of only a few hundred lines of code with no backend infrastructure. Gemal has made the project open-source, with the code publicly available on GitHub. == Functionality == WikiTok serves users completely random Wikipedia article snippets from Wikipedia's nearly 9.5 million entries. Each article preview includes a full-screen image from Wikipedia and a short text excerpt. Users can click "Read More" to access the full Wikipedia article, or continue scrolling to see the next random entry. The application functions as a progressive web app that can be downloaded as a hybrid between an app and a website. It works on both mobile and desktop browsers, and is designed to be responsive whether users scroll with their thumb on mobile devices or use a cursor on desktop computers. As of 2025, WikiTok supports 14 different languages for article translation. == Philosophy == Gemal has explicitly positioned WikiTok as "anti-algorithmic," resisting numerous requests to implement personalized content algorithms. In an interview with Business Insider, Gemal stated: "I have had plenty of people message me and even make issues on my GitHub asking for some insane crazy WikiTok algorithm... we're already ruled by ruthless, opaque algorithms in our everyday life; why can't we just have one little corner in the world without them?" The application aims to combat "doomscrolling" – the practice of mindlessly consuming negative news online that can cause anxiety, helplessness, and anger. Unlike traditional social media platforms, WikiTok deliberately excludes algorithms, advertisements, and user tracking.

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  • Immediate mode (computer graphics)

    Immediate mode (computer graphics)

    Immediate mode is an API design pattern in computer graphics libraries, in which the client calls directly cause rendering of graphics objects to the display, or in which the data to describe rendering primitives is inserted frame by frame directly from the client into a command list (in the case of immediate mode primitive rendering), without the use of extensive indirection – thus immediate – to retained resources. It does not preclude the use of double-buffering. Retained mode is an alternative approach. Historically, retained mode has been the dominant style in GUI libraries; however, both can coexist in the same library and are not necessarily exclusive in practice. == Overview == In immediate mode, the scene (complete object model of the rendering primitives) is retained in the memory space of the client, instead of the graphics library. This implies that in an immediate mode application, the lists of graphical objects to be rendered are kept by the client and are not saved by the graphics library API. The application must re-issue all drawing commands required to describe the entire scene each time a new frame is required, regardless of actual changes. This method provides on the one hand a maximum of control and flexibility to the application program, but on the other hand it also generates continuous work load on the CPU. Examples of immediate mode rendering systems include Direct2D, OpenGL and Quartz. There are some immediate mode GUIs that are particularly suitable when used in conjunction with immediate mode rendering systems. == Immediate mode primitive rendering == Primitive vertex attribute data may be inserted frame by frame into a command buffer by a rendering API. This involves significant bandwidth and processor time (especially if the graphics processing unit is on a separate bus), but may be advantageous for data generated dynamically by the CPU. It is less common since the advent of increasingly versatile shaders, with which a graphics processing unit may generate increasingly complex effects without the need for CPU intervention. == Immediate mode rendering with vertex buffers == Although drawing commands have to be re-issued for each new frame, modern systems using this method are generally able to avoid the unnecessary duplication of more memory-intensive display data by referring to that unchanging data (via indirection) (e.g. textures and vertex buffers) in the drawing commands. == Immediate mode GUI == Graphical user interfaces traditionally use retained mode-style API design, but immediate mode GUIs instead use an immediate mode-style API design, in which user code directly specifies the GUI elements to draw in the user input loop. For example, rather than having a CreateButton() function that a user would call once to instantiate a button, an immediate-mode GUI API may have a DoButton() function which should be called whenever the button should be on screen. The technique was developed by Casey Muratori in 2002. Prominent implementations include Omar Cornut's Dear ImGui in C++, Nic Barker's Clay in C and Micha Mettke's Nuklear in C.

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  • Closest point method

    Closest point method

    The closest point method (CPM) is an embedding method for solving partial differential equations on surfaces. The closest point method uses standard numerical approaches such as finite differences, finite element or spectral methods in order to solve the embedding partial differential equation (PDE) which is equal to the original PDE on the surface. The solution is computed in a band surrounding the surface in order to be computationally efficient. In order to extend the data off the surface, the closest point method uses a closest point representation. This representation extends function values to be constant along directions normal to the surface. == Definitions == Closest Point function: Given a surface S , c p ( x ) {\displaystyle {\mathcal {S}},cp(\mathbf {x} )} refers to a (possibly non-unique) point belonging to S {\displaystyle {\mathcal {S}}} , which is closest to x {\displaystyle \mathbf {x} } [SE]. Closest point extension: Let S {\displaystyle {\mathcal {S}}} , be a smooth surface in R d {\displaystyle \mathbb {R} ^{d}} . The closest point extension of a function u : S → R {\displaystyle u:{\mathcal {S}}\rightarrow \mathbb {R} } , to a neighborhood Ω {\displaystyle \Omega } of S {\displaystyle {\mathcal {S}}} , is the function v : Ω → R {\displaystyle v:\Omega \rightarrow \mathbb {R} } , defined by v ( x ) = u ( c p ( x ) ) {\displaystyle v(\mathbf {x} )=u(cp(\mathbf {x} ))} . == Closest point method == Initialization consists of these steps [EW]: If it is not already given, a closest point representation of the surface is constructed. A computational domain is chosen. Typically this is a band around the surface. Replace surface gradients by standard gradients in R 3 {\displaystyle \mathbb {R} ^{3}} . Solution is initialized by extending the initial surface data on to the computational domain using the closest point function. After initialization, alternate between the following two steps: Using the closest point function, extend the solution off the surface to the computational domain. Compute the solution to the embedding PDE on a Cartesian mesh in the computational domain for one time step. == Banding == The surface PDE is extended into R 3 {\displaystyle \mathbb {R} ^{3}} however it is only necessary to solve this new PDE near the surface. Hence, we solve the PDE in a band surrounding the surface for efficient computational purposes. Ω c x : ‖ x − c p ( x ) ‖ 2 ≤ λ {\displaystyle \Omega _{c}{x:\|x-cp(x)\|_{2}\leq \lambda }} where λ {\displaystyle \lambda } is the bandwidth. == Example: Heat equation on a circle == Using initial profile u S ( θ , t ) = sin ⁡ ( θ ) {\displaystyle u_{S}(\theta ,t)=\sin(\theta )} leads to the solution u S ( θ , t ) = exp ⁡ ( − t ) sin ⁡ ( θ ) {\displaystyle u_{S}(\theta ,t)=\exp(-t)\sin(\theta )} for the heat equation. Forward Euler time-stepping is used with relation Δ t = 0.1 Δ x 2 {\displaystyle \Delta t=0.1\Delta x^{2}} and degree-four interpolation polynomials for the interpolations. Second-order centered differences are used for the spatial discretization. The CPM results in the expected second order error in the solution u {\displaystyle u} . == Applications == The closest point method can be applied to various PDEs on surfaces. Reaction–diffusion problems on point clouds [RD], eigenvalue problems [EV], and level set equations [LS] are a few examples.

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  • ImHex

    ImHex

    ImHex is a free cross-platform hex editor available on Windows, macOS, and Linux. ImHex is used by programmers and reverse engineers to view and analyze binary data. == History == The initial release of the project in November 2020, saw significant interest on GitHub. == Features == Features include: Hex editor Custom pattern matching and analysis scripting language Visual, node based data pre-processor Disassembler Running and visualizing of YARA rules Bookmarks Binary data diffing Additional Tools MSVC, Itanium, D and Rust name demangler ASCII table Calculator Base converter File utilities IEEE 754 floating point decoder Division by invariant multiplication calculator TCP/IP client and server Support for: Data importing and exporting ASCII string, Unicode string, numeric, hexadecimal and regular expressions search Byte manipulation File hashing Plug-ins

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  • Misskey

    Misskey

    Misskey (Japanese: ミスキー, romanized: Misukī) is an open source, federated, social networking service created in 2014 by Japanese software engineer Eiji "syuilo" Shinoda. Misskey uses the ActivityPub protocol for federation, allowing users to interact between independent Misskey instances, and other ActivityPub compatible platforms. Misskey is generally considered to be part of the Fediverse. Despite being a decentralized service, Misskey is not philosophically opposed to centralization. The name Misskey comes from the lyrics of Brain Diver, a song by the Japanese singer May'n. == History == Misskey was initially developed as a BBS-style internet forum by high school student Eiji Shinoda in 2014. After introducing a timeline feature, Misskey gained popularity as the microblogging platform it is today. In 2018, Misskey added support for ActivityPub, becoming a federated social media platform. The flagship Misskey server, Misskey.io, was started on April 15, 2019. Misskey, alongside Mastodon and Bluesky, has received attention as a potential replacement for Twitter following Twitter's acquisition by Elon Musk in 2022. On April 8, 2023, Misskey.io incorporated as MisskeyHQ K.K. As of February 2024, over 450,000 users were registered, making it the largest instance of Misskey. Misskey.io is crowdfunded. The administrator of Misskey.io is Japanese system administrator Yoshiki Eto, who operates under the alias Murakami-san. Eiji Shinoda serves as director. In July 2023, Twitter introduced extreme restrictions on their API in order to combat scraping from bots. Some users were critical of the changes, and as a result migrated to other social networks. The number of users registering on Misskey.io, Misskey's official instance and the largest one, increased rapidly, with other Misskey instances also receiving a spike in signups. In response to this trend, Skeb, a platform for sharing art, announced on July 14, 2023 that it would sponsor the Misskey development team. In early 2024, Misskey was targeted by a spam attack from Japan. The cause of the attack is believed to be a dispute between rival groups on a Japanese hacker forum and a DDoS attack on a Discord bot. Mastodon instances with open registration were used in the attack. In November 2025, Eto announced intentions to replace ActivityPub with Misskey's own low-overhead federation system in "a few years". Shinoda later said that this was "fake news". == Development == Misskey is open source software and is licensed under the AGPLv3. The Misskey API is publicly available and is documented using the OpenAPI Specification, which allows users to build automated accounts and use it on any Misskey instance. The service is translated using Crowdin. Misskey is developed using Node.js. TypeScript is used on both the frontend and backend. PostgreSQL is used as its database. Vue.js is used for the frontend. == Functionality == Posts on Misskey are called "notes". Notes are limited to a maximum of 3,000 characters (a limit which can be customized by instances), and can be accompanied by any file, including polls, images, videos, and audio. Notes can be reposted, either by themselves or with another "quote" note. Misskey comes with multiple timelines to sort through the notes that an instance has available, and are displayed in reverse chronological order. The Home timeline shows notes from users that you follow, the Local timeline shows all notes from the instance in use, the Social timeline shows both the Home and Local timeline, and the Global timeline shows every public note that the instance knows about. Notes have customizable privacy settings to control what users can see a note, similar to Mastodon's post visibility ranges. Public notes show up on all timelines, while Home notes only show on a user's Home timeline. Notes can also be set to be available only for followers. Direct messages using notes can be sent to users.

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  • Boyfriend Maker

    Boyfriend Maker

    Boyfriend Maker was a dating sim, romance chatbot smartphone app for iOS (iPhone) and Android devices, developed by Japanese studio 36 You Games (styled as 36You) and distributed under the freemium business model. Boyfriend Maker incorporated advanced artificial intelligence chat technology a decade before products such as ChatGPT. According to the developer's website, Boyfriend Maker is an "app that lets you interact and chat with quirky virtual boyfriends". While each virtual boyfriend has certain unique characteristics, the various instances of the boyfriend are powered by a chat engine, that (at least within a language and market) can utilise vocabulary and knowledge acquired in a chat with one user in subsequent chats with other users. == Gameplay == Users gain experience points and in-game coins. Users can customize their virtual boyfriend's appearance by selecting items such as hair, clothing, face, and a necklace. == Apple delisting and reintroduction == In late November 2012, the original iOS Boyfriend Maker app was delisted from the Apple App Store due to "ribald" chat, according to the New York Times. Boyfriend Maker was removed by Apple due to "reports of references to violent sexual acts and pedophilia". Boyfriend Maker had an age rating of 4+, even though the chat bot "responds with often strange and explicit text unsuitable for young children". User-posted chat excerpts indicate that the virtual boyfriend would sometimes transition abruptly to sexual chat in response to a seemingly innocent question. In one user-posted example, in response to the question, "what kind of wedding cake will we have" the boyfriend responds, "a good sex ima be on top of u u gonna ride oon me bitin the pillow gurrl ima fuck da shit out of u". The developer's use of the SimSimi-created third-party chat engine may be responsible for the sexual text. As the virtual boyfriend converses with human users, the SimSimi chat engine acquires vocabulary from users of the game and applies this "learned" vocabulary in chats with other users. The chat engine might also employ lines harvested from human-human chat logs, song lyrics, movies or TV shows. In April 2013, a detuned and presumably tamer version of the app, titled Boyfriend Plus, was permitted on Apple's App Store.

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  • Tute Genomics

    Tute Genomics

    Tute Genomics was an American genomics startup that provided a cloud-based web application for rapid and accurate annotation of human genomic data. It was built on the expertise of ANNOVAR. Tute Genomics assisted researchers in identifying disease genes and biomarkers, and assisted clinicians/labs in performing genetic diagnosis. Based in Provo, Utah, Tute was co-founded by Dr. Kai Wang, an assistant professor at the University of Southern California (USC); and Dr. Reid J. Robison, a board-certified psychiatrist with fellowship training in both neurodevelopmental genetics and bioinformatics. Tute Genomics was acquired by PierianDX in 2016. == History == The word "tute" means "personal" in the Na’vi language created for the 2009 film Avatar by Paul Frommer, a linguist and communications professor at the USC Marshall School of Business. === Timeline === 2013 Tute Genomics launched in 2013 and entered the accelerator, BoomStartup. By "demo day" of BoomStartup, Tute had raised their seed round of funding and expanded the round to include angel investors from SLC Angels, Park City Angels, Life Science Angels. Tute was the tenth ever online syndicate for AngelList and in all raised a seed round of $1.5 million. 2014 In March 2014, the company announced that Affiliated Genetics, a Utah-based CLIA-certified laboratory, selected Tute Genomics for its next-generation sequencing (NGS) analytics pipeline. In May 2014, the company announced joining the Global Alliance for Genomics and Health. In June 2014, Advanced Biological Laboratories (ABL), S.A., announced a licensing and collaboration agreement with Tute Genomics and the commercial launch of OncoChek for managing and analysing genomics data in the field of oncology. In July 2014, the company announced an agreement with Lineagen, Inc., to provide next-generation sequencing analytics for Lineagen’s NextStepDx Plus assay. Also, Brigham Young University selected the Tute Genomics genome annotation and discovery platform for analysis and interpretation of 1,000 exomes and genomes. In November 2014, the company announced addition of the Tute platform to Illumina’s BaseSpace. The company announced a Series A1 funding round of $2.3 million in December 2014. The round was led by UK-based Eurovestech. Peak Ventures and a number of angel investors also participated in this round. 2015 Tute recruits David Mittelman, founder of Arpeggi, Inc. and former CSO at FamilyTreeDNA, to Tute Genomics as Chief Scientific Officer. Tute acquires Knome and integrates the KnoSys platform into its software product. 2016 Reid Robison, Tute CEO, launches a Kickstarter campaign to sell Tute interpreted whole genome and whole exome sequencing directly to consumers. The campaign was suspended within the same month after receiving a letter from the United States Food and Drug Administration. Tute is acquired by PierianDX.

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  • The Outliner of Giants

    The Outliner of Giants

    The Outliner of Giants was commercial outlining software. Like other outliners, it allowed the user to create a document consisting of a series of nested lists. It was one of a number of browser-based outliners that are delivered as a web application, used through a web browser, rather than being installed as a stand-alone application. The Outliner of Giants was released in 2009. The service was shut down on December 31, 2017 and only exports are allowed at this time. == Feature set == Unlike most other browser-based outliners - which often focus on providing a minimum viable product - the Outliner of Giants had much of the functionality typically associated with a desktop outliner, such as the ability to use of columns to structure information. However, The Outliner of Giants did not support offline editing, requiring an active internet connection in order to make changes to an outline document. === Outlining === Like all outliners, The Outliner of Giants supported the creation of a hierarchy of items, with users modifying the parent-child relationship between items in order to structure a document. This included the ability to promote or demote items up or down the hierarchy, or move an item up or down a list of siblings on the same level. The Outliner of Giants did not support the true cloning of items (where an item can appear to be in multiple places within the hierarchy at the same time), although it did support the copying of single or multiple nodes. === Import === The Outliner of Giants could import both plain text and the OPML XML format, which is commonly used to transfer data between outlining applications. === Editing === Outline documents could be edited using a WYSIWYG editor, as well as the Markdown, and Textile markup languages. === Annotation === The Outliner of Giants supported functions to annotate an outline, such as the ability to add colored labels, highlights and text, as well as tags and hashtags. === Collaboration === The Outliner of Giants supported real-time collaboration, where multiple users could edit the same document, and can see the changes made by another user as they happened. === Publication === Outlines created through The Outliner of Giants could be published directly online through the service, either as outlines, pages or in a blog format. === Export === The Outliner of Giants can export outline data as plain text, HTML, as well as directly to the Google Docs word processor.

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  • Site-specific browser

    Site-specific browser

    A site-specific browser (SSB) is a software application dedicated to accessing pages from a single source (site) on a computer network such as the Internet or a private intranet. SSBs typically simplify the more complex functions of a web browser by excluding the menus, toolbars and browser graphical user interface associated with functions that are external to the workings of a single site. Modern site-specific browsers range from simple browser windows without navigation controls to sophisticated desktop applications built with frameworks like Electron that bundle entire browser engines. This evolution has enabled many popular desktop applications to be built using web technologies, effectively making them advanced site-specific browsers. == History == === Early development === One of the earliest examples of an SSB was MacDICT, a Mac OS 9 application that accessed various websites to define, translate, or find synonyms for words typed into a text box. However, the first general-purpose SSB is considered to be Bubbles, which launched in late 2005 on the Windows platform. Bubbles introduced the term "Site Specific Extensions" for SSB userscripts and created the first SSB JavaScript API. In 2007, Mozilla announced Prism (originally called WebRunner), a project to integrate web applications with the desktop. That same year, Todd Ditchendorf, a former Apple Dashboard engineer, released Fluid for macOS. On 2 September 2008, Google Chrome was released with a built-in "Create application shortcut" feature, bringing SSB functionality to mainstream users. This feature allowed any website to be launched in a separate window without the browser interface. === Modern era === The landscape of site-specific browsers changed dramatically with the introduction of Electron in 2013 (originally called Atom Shell). Electron combined Chromium and Node.js into a single runtime, enabling developers to build desktop applications using web technologies. This framework has since powered applications used by hundreds of millions of users, including Visual Studio Code, Slack, Discord, and Microsoft Teams. In 2015, the concept of Progressive Web Apps (PWAs) was introduced by Google engineers Alex Russell and Frances Berriman, representing a parallel evolution in web-to-desktop technology. While PWAs share similar goals with SSBs, they follow web standards and can be installed directly from browsers. More recently, alternative frameworks like Tauri have emerged, offering significantly smaller application sizes by using the system's native web renderer instead of bundling Chromium. == Technical implementation == Site-specific browsers can be implemented through various approaches: === Browser-based SSBs === The simplest form of SSB is created through browser features that allow websites to run in separate windows without the standard browser interface. Modern Chromium-based browsers offer "Install as app" or "Create shortcut" functionality that creates a dedicated window for a specific website. These SSBs share the browser's underlying engine and resources but operate in isolated windows. === Framework-based SSBs === More sophisticated SSBs are built using application frameworks: Electron: Bundles a complete Chromium browser with Node.js, resulting in applications of 85MB or larger. Each Electron application runs its own browser instance, providing full access to system APIs but consuming significant resources. Tauri: Uses the operating system's native web rendering engine (WebView2 on Windows, WebKit on macOS, and WebKitGTK on Linux), resulting in applications typically 2.5-10MB in size. Other frameworks: Include Neutralino.js (ultra-lightweight using system browser), Wails (Go-based), and the Chromium Embedded Framework (CEF). == Comparison with Progressive Web Apps == While site-specific browsers and Progressive Web Apps (PWAs) share the goal of bringing web content to the desktop, they differ in several key aspects: == Applications == Site-specific browsers have become the foundation for many popular desktop applications: Communication and collaboration: Many modern communication tools are built as SSBs, including Slack, Discord, Microsoft Teams, and WhatsApp Desktop. These applications benefit from web-based development while providing desktop integration. Development tools: Visual Studio Code, used by 73.6% of developers according to Stack Overflow's 2024 survey, is built with Electron, as are Atom and GitHub Desktop. Productivity software: Applications like Notion, Obsidian, and various project management tools use SSB technology to provide consistent experiences across platforms. Security and Privacy: Web browsers can be modified to only have access to a single site, in order to protect the security and privacy of the user via compartmentalization == Security and performance == === Memory usage === Framework-based SSBs, particularly those using Electron, are known for high memory consumption. Studies show Electron applications typically use 120-300MB at baseline, with complex applications consuming significantly more. This is approximately 5-10 times more memory than equivalent native applications. === Security considerations === SSBs can provide security benefits through process isolation, where each application runs in its own sandboxed environment. However, bundling an entire browser engine also means each application must be updated independently to patch security vulnerabilities. Research presented at the Network and Distributed System Security (NDSS) Symposium has identified various security challenges specific to Electron applications. === Bundle sizes === The choice of framework significantly impacts application size: Electron applications: 85MB+ (includes full Chromium) Tauri applications: 2.5-10MB (uses system WebView) Browser-based SSBs: No additional download (uses existing browser) == Software == === Browser support === Most modern browsers provide some form of SSB functionality: Chromium-based browsers (Google Chrome, Microsoft Edge, Brave, Opera, Vivaldi): "Install as app" or "Create shortcut" feature Safari: "Add to Dock" feature in macOS Sonoma (2023) Firefox: Removed SSB support in December 2020 (version 85) GNOME Web: "Install Site as Web Application" feature === Standalone tools === ==== Active ==== WebCatalog (Windows, macOS, Linux) – Manages multiple SSBs with isolated storage Fluid (macOS) – Pioneering SSB creator for Mac Unite (macOS) – Creates SSBs with customization options Coherence X (macOS) – Advanced SSB creation tool Pake (cross-platform) – Open-source SSB creator Wavebox (cross-platform) – Workspace browser with SSB features ==== Discontinued ==== Mozilla Prism – Cross-platform SSB creator (discontinued 2011) Nativefier – Command-line SSB creator (discontinued 2023) Epichrome – macOS SSB creator (discontinued 2021) === Development frameworks === Electron – Most popular framework, bundles Chromium and Node.js Tauri – Rust-based framework using system WebView Chromium Embedded Framework (CEF) – C++ library for embedding Chromium Neutralino.js – Lightweight framework using system browser Wails – Go-based framework for web frontends

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  • Croissant (metadata format)

    Croissant (metadata format)

    Croissant is a metadata format design to support sharing of datasets for machine learning applications. It is a platform-agnostic schema used to standardize metadata in data repositories like Hugging Face, kaggle, Dataverse and OpenML. == Structure == Croissant builds upon schema.org, uses primarily JSON-LD, and divides metadata in four "layers": Dataset Metadata, Resource, Structure and Semantic: The Dataset Metadata layer constrains which schema.org properties should be used, including additional properties, linking together the resources (files) of the dataset with general metadata, like licensing and citation information. The Resource layer describes the individual files and sets of those using two new classes, FileObject and FileSet. A FileSet may be a collection of related images. The Structure layer specifies how the files are organized in the dataset. A RecordSet class describes how resources are present, configurations that may very a lot between modality. This specification facilitates interoperability of the datasets. Finally, the Semantic layer adds information for practical reuse of the dataset, such as splits for train, test and validation subsets. It also provides a default extension for metadata related to responsible AI. The use of a standard machine-readable structure increases, for example, the discoverability of datasets in search engines such as Google Dataset Search. == History == Croissant was shared in arXiv in March 2024 and published in the proceedings of NeurIPS 2024. It started as community driven as a MLCommons Croissant Working Group, including stakeholders organizations from academia and industry, including Google, the open data institute, Sage Bionetworks and King's College London. Variations of Croissant are developed to support datasets in different areas of research, such as Geo-Croissant for geospatial datasets. Other technical extensions, such as support for RDF, soon followed.

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  • SlideRocket

    SlideRocket

    SlideRocket was an online presentation platform that let users create, manage, share and measure presentations. SlideRocket was provided via a SaaS model. The company was acquired by VMware in April 2011, who sold it to ClearSlide, a similar SaaS application, in March 2013. It is no longer offering independent signups, as the platform is being integrated into ClearSlide. == History == SlideRocket was founded in Jan 2006, and launched as a private beta in March 2008 at the Under The Radar Spring event. A public beta was announced in September 2008 followed shortly by public release on October 28, 2008. SlideRocket is most commonly credited with inventing the PResuMÉ or Presentation Résumé in early 2009. On April 26, 2011, SlideRocket was acquired by VMware. On March 5, 2013, VMware sold SlideRocket to ClearSlide. SlideRocket is based in San Francisco.

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  • Bring your own encryption

    Bring your own encryption

    Bring your own encryption (BYOE), also known as bring your own key (BYOK), is a cloud computing security model that allows cloud service customers to use their own encryption software and manage their own encryption keys. == Overview == BYOE enables cloud service customers to utilize a virtual instance of their encryption software alongside their cloud-hosted business applications to encrypt their data. In this model, hosted business applications are configured to process all data through the encryption software. This software then writes the ciphertext version of the data to the cloud service provider's physical data store and decrypts ciphertext data upon retrieval requests. This approach provides enterprises with control over their keys and the ability to generate their own master key using internal hardware security modules (HSM), which are then transmitted to the cloud provider's HSM. When the data is no longer needed, such as when users discontinue the cloud service, the keys can be deleted, rendering the encrypted data permanently inaccessible. This practice is known as crypto-shredding. == Potential Advantages == Organizations can store data with unique encryption that only they can access. Multiple organizations can share the same hardware infrastructure via cloud services like Amazon Web Services (AWS) or Google Cloud while maintaining encryption to comply with regulations such as HIPAA. == Potential Challenges == Resource utilization may be higher compared to traditional encryption practices when multiple users share the same hardware and use their own encryption. Efforts to minimize resource utilization issues may potentially impact security benefits.

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