AI Face Live

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  Site reliability engineering

  Site reliability engineering (SRE) is a discipline in the field of software engineering and IT infrastructure support that monitors and improves the availability and performance of deployed software systems and large software services (which are expected to deliver reliable response times across events such as new software deployments, hardware failures, and cybersecurity attacks). There is typically a focus on automation and an infrastructure as code methodology. SRE uses elements of software engineering, IT infrastructure, web development, and operations to assist with reliability. It is similar to DevOps as they both aim to improve the reliability and availability of deployed software systems. == History == Site Reliability Engineering originated at Google with Benjamin Treynor Sloss, who founded SRE team in 2003. The concept expanded within the software development industry, leading various companies to employ site reliability engineers. By March 2016, Google had more than 1,000 site reliability engineers on staff. Dedicated SRE teams are common at larger web development companies. In middle-sized and smaller companies, DevOps teams sometimes perform SRE, as well. Organizations that have adopted the concept include Airbnb, Dropbox, IBM, LinkedIn, Netflix, and Wikimedia. == Definition == Site reliability engineers (SREs) are responsible for a combination of system availability, latency, performance, efficiency, change management, monitoring, emergency response, and capacity planning. SREs often have backgrounds in software engineering, systems engineering, and/or system administration. The focuses of SRE include automation, system design, and improvements to system resilience. SRE is considered a specific implementation of DevOps; focusing specifically on building reliable systems, whereas DevOps covers a broader scope of operations. Despite having different focuses, some companies have rebranded their operations teams to SRE teams. == Principles and practices == Common definitions of the practices include (but are not limited to): Automation of repetitive tasks for cost-effectiveness. Defining reliability goals to prevent endless effort. Design of systems with a goal to reduce risks to availability, latency, and efficiency. Observability, the ability to ask arbitrary questions about a system without having to know ahead of time what to ask. Common definitions of the principles include (but are not limited to): Toil management, the implementation of the first principle outlined above. Defining and measuring reliability goals—SLIs, SLOs, and error budgets. Non-Abstract Large Scale Systems Design (NALSD) with a focus on reliability. Designing for and implementing observability. Defining, testing, and running an incident management process. Capacity planning. Change and release management, including CI/CD. Chaos engineering. == Deployment == SRE teams collaborate with other departments within organizations to guide the implementation of the mentioned principles. Below is an overview of common practices: === Kitchen Sink === Kitchen Sink refers to the expansive and often unbounded scope of services and workflows that SRE teams oversee. Unlike traditional roles with clearly defined boundaries, SREs are tasked with various responsibilities, including system performance optimization, incident management, and automation. This approach allows SREs to address multiple challenges, ensuring that systems run efficiently and evolve in response to changing demands and complexities. === Infrastructure === Infrastructure SRE teams focus on maintaining and improving the reliability of systems that support other teams' workflows. While they sometimes collaborate with platform engineering teams, their primary responsibility is ensuring up-time, performance, and efficiency. Platform teams, on the other hand, primarily develop the software and systems used across the organization. While reliability is a goal for both, platform teams prioritize creating and maintaining the tools and services used by internal stakeholders, whereas Infrastructure SRE teams are tasked with ensuring those systems run smoothly and meet reliability standards. === Tools === SRE teams utilize a variety of tools with the aim of measuring, maintaining, and enhancing system reliability. These tools play a role in monitoring performance, identifying issues, and facilitating proactive maintenance. For instance, Nagios Core is commonly employed for system monitoring and alerting, while Prometheus (software) is frequently used for collecting and querying metrics in cloud-native environments. === Product or Application === SRE teams dedicated to specific products or applications are common in large organizations. These teams are responsible for ensuring the reliability, scalability, and performance of key services. In larger companies, it's typical to have multiple SRE teams, each focusing on different products or applications, ensuring that each area receives specialized attention to meet performance and availability targets. === Embedded === In an embedded model, individual SREs or small SRE pairs are integrated within software engineering teams. These SREs collaborate with developers, applying core SRE principles—such as automation, monitoring, and incident response—directly to the software development lifecycle. This approach aims to enhance reliability, performance, and collaboration between SREs and developers. === Consulting === Consulting SRE teams specialize in advising organizations on the implementation of SRE principles and practices. Typically composed of seasoned SREs with a history across various implementations, these teams provide insights and guidance for specific organizational needs. When working directly with clients, these SREs are often referred to as 'Customer Reliability Engineers.' In large organizations that have adopted SRE, a hybrid model is common. This model includes various implementations, such as multiple Product/Application SRE teams dedicated to addressing the specific reliability needs of different products. An Infrastructure SRE team may collaborate with a Platform engineering group to achieve shared reliability goals for a unified platform that supports all products and applications. == Industry == Since 2014, the USENIX organization has hosted the annual SREcon conference, bringing together site reliability engineers from various industries. This conference is a platform for professionals to share knowledge, explore effective practices, and discuss trends in site reliability engineering.

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  OpenPipeline

  openPipeline is an open-source plug-in for Autodesk Maya that is designed to assist in a Production Pipeline structure and Computer animation. == Development == Created in Maya Embedded Language, openPipeline was initiated at Eyebeam Atelier and further developed at Pratt Institute in the Digital Arts Lab. The initial release date was December 28, 2006. == Contributors == Rob O'Neill (Creator) Paris Mavroidis Meng-Han Ho

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  Automate This

  Automate This: How Algorithms Came to Rule Our World is a book written by Christopher Steiner and published by Penguin Group. == Book == Steiner begins his study of algorithms on Wall Street in the 1980s but also provides examples from other industries. For example, he explains the history of Pandora Radio and the use of algorithms in music identification. He expresses concern that such use of algorithms may lead to the homogenization of music over time. Steiner also discusses the algorithms that eLoyalty (now owned by Mattersight Corporation following divestiture of the technology) was created by dissecting 2 million speech patterns and can now identify a caller's personality style and direct the caller with a compatible customer support representative. Steiner's book shares both the warning and the opportunity that algorithms bring to just about every industry in the world, and the pros and cons of the societal impact of automation (e.g. impact on employment).

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  Sensory, Inc.

  Sensory, Inc. is an American company which develops software AI technologies for speech, sound and vision. It is based in Santa Clara, California. Sensory’s technologies have shipped in over three billion products from hundreds of leading consumer electronics manufacturers including AT&T, Hasbro, Huawei, Google, Amazon, Samsung, LG, Mattel, Motorola, Plantronics, GoPro, Sony, Tencent, Garmin, LG, Microsoft, Lenovo, and more. Sensory has over 60 issued patents covering speech recognition in consumer electronics, biometric authentication, sensor/speech combinations, wake word technology, and more. == History == Sensory, Inc. was founded in 1994, originally as Sensory Circuits, by Forrest Mozer, Mike Mozer and Todd Mozer. The three had also co-founded ESS Technology years earlier. In 1999 Sensory acquired Fluent Speech Technologies, which was formed and started by a group of professors out of the Oregon Graduate Institute (formerly OGI, now OHSU). Fluent Speech Technologies developed high performance embedded speech engines, the technology from this acquisition is now the core technology used throughout Sensory's chip and software line. === Company timeline === 1994 – Founded 1995 – Introduces the RSC 164 - first commercially successful speech recognition IC 1998 – Introduces first speaker verification IC 2000 – Acquires Oregon based Fluent-Speech Technologies 2002 – Acquires Texas Instruments line of speech output ICs (the SC series) 2007 – Introduces first Voice User Interface for Bluetooth silicon (CSR BC-5) - BlueGenie 2008 - Sensory and BlueAnt partner on the V1 - Revolutionary new Bluetooth headset with a voice user interface. First wearable to use a voice user interface for control and best-reviewed speech recognition product in history 2009 – Introduced world's smallest text to speech system (TTS) and Truly HandsfreeTM Triggers/ wake words. 2010 – Introduced the NLP-5x – First Natural Language Voice Processor and TrulyHandsfree wake words in SDKs for Android, iOS, Linux, and Windows. NLP5x used the first generation of TrulyHandsfree wake words with low power and enhanced accuracy. 2011 – Sensory partners with Google and Microsoft to enable TrulyHandsfree as a front end to Goog411 and Bing411 2012 – Partnered with Tensilica to offer ultra-low power TrulyHandsfree wake words; introduced Speaker Verification and Speaker Identification for mobile phones and other consumer electronics. 2012 - TrulyHandsfree released into Samsung's Galaxy S2 for "Hey Galaxy" wake word 2013 – TrulyHandsfree wake words migrated to many new platforms and began shipping as MotoVoice in the Google-owned MotoX. Sensory's TrulyHandsfree in mobile takes off with the Galaxy S3 and S4 and Galaxy Note and is licensed into wearables like Google Glass. 2014 – Announced new initiative in Vision; added LG and Motorola as customers; received the 2014 Global Mobile Award for Best Mobile Technology Breakthrough at the GSMA Mobile World Congress in Barcelona, Spain (judges commented, "A big advance for the wearables market, this offers many benefits for consumers, increasing uptake and usage of many mobile apps, driving revenue for operators and content providers.") 2015-2018 - Licensed Google, Amazon, MSFT, Baidu, Huawei, ZTE, and many others with TrulyHandsfree wake words. Sensory develops first wake words for OK Google, Hey Siri, and Hey Cortana. 2019 - Sensory launched two new solutions: SoundID, sound identification, and TrulyNatural, embedded large vocabulary speech recognition. Sensory also acquired Vocalize.ai, an independent testing lab. 2020 - Sensory introduced VoiceHub, which allows the automated generation of wake words. 2021 - Sensory expands VoiceHub with speech recognition and NLU capabilities. The company initiated a new cloud platform, SensoryCloud.ai. 2022-Sensory rolls out SensoryCloud.ai with speech to text, text to speech, face & voice biometrics 2024- Sensory Automotive & TrulyNatural Speech-to-text On-Device launched == Technology and products == Sensory originally developed both hardware (Integrated Circuit - IC or "chip") and software platforms but migrated to software only around 2005 and added cloud and hybrid computing capabilities in 2021. Sensory's RSC-164 IC (Integrated Circuit or "chip") was used on NASA's Mars Polar Lander in the Mars Microphone on the Lander. Speech Synthesis SC-6x chips – acquired some speech synthesis technology from Texas Instruments. Sensory’s embedded AI solutions include the following: TrulyHandsfree (THF) - wake word detection and phrase spotting. TrulyNatural (TNL) - large vocabulary continuous speech recognition with NLU. TrulySecure (TS) - face and voice biometrics. TrulySecureSpeakerVerification (TSSV) - speaker and sound identification. VoiceHub - Online portal for creating custom wake words and speech recognition models with NLU. Sensory Automotive- Sensory Automotive is a full voice and vision suite of AI technologies that operate efficiently in the car without connecting to a network. The cloud initiative, SensoryCloud.ai, is targeting Speech To Text (STT), Text To Speech (TTS), Wake Word verification, face and voice recognition, and sound identification.

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  Elowan

  Elowan is a plant-robot cyborg. Using its own internal bioelectrical signals, The plant has a robotic extension that makes it move towards light sources. Electrodes are inserted into the leaves, stem, and ground to detect the faint bioelectrical signals the plant produces. Then they are amplified so the robot can read them. So when the plant "wants" to go to light, the cyborg automatically goes to the nearest light source. Future extensions of the robot could provide: Protection, growth frameworks, and nutrients. Other factors that could make the cyborg move are temperature, soil, and gravity conditions Elowan is one in a series of plant-electronic hybrid experiments.

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  COVID-19 apps

  COVID-19 apps include mobile-software applications for digital contact-tracing—i.e. the process of identifying persons ("contacts") who may have been in contact with an infected individual—deployed during the COVID-19 pandemic. Numerous tracing applications have been developed or proposed, with official government support in some territories and jurisdictions. Several frameworks for building contact-tracing apps have been developed. Privacy concerns have been raised, especially about systems that are based on tracking the geographical location of app users. Less overtly intrusive alternatives include the co-option of Bluetooth signals to log a user's proximity to other cellphones. (Bluetooth technology has form in tracking cell-phones' locations.)) On 10 April 2020, Google and Apple jointly announced that they would integrate functionality to support such Bluetooth-based apps directly into their Android and iOS operating systems. India's COVID-19 tracking app Aarogya Setu became the world's fastest growing application—beating Pokémon Go—with 50 million users in the first 13 days of its release. == Rationale == Contact tracing is an important tool in infectious disease control, but as the number of cases rises time constraints make it more challenging to effectively control transmission. Digital contact tracing, especially if widely deployed, may be more effective than traditional methods of contact tracing. In a March 2020 model by the University of Oxford Big Data Institute's Christophe Fraser's team, a coronavirus outbreak in a city of one million people is halted if 80% of all smartphone users take part in a tracking system; in the model, the elderly are still expected to self-isolate en masse, but individuals who are neither symptomatic nor elderly are exempt from isolation unless they receive an alert that they are at risk of carrying the disease. Some proponents advocate for legislation exempting certain COVID-19 apps from general privacy restrictions. == Issues == === Uptake === Ross Anderson, professor of security engineering at Cambridge University, listed a number of potential practical problems with app-based systems, including false positives and the potential lack of effectiveness if takeup of the app is limited to only a small fraction of the population. In Singapore, only one person in three had downloaded the TraceTogether app by the end of June 2020, despite legal requirements for most workers; the app was also underused, as it required users to keep it open at all times on iOS. A team at the University of Oxford simulated the effect of a contact tracing app on a city of 1 million. They estimated that if the app was used in conjunction with the shielding of over-70s, then 56% of the population would have to be using the app for it to suppress the virus. This would be equivalent to 80% of smartphone users in the United Kingdom. They found that the app could still slow the spread of the virus if fewer people downloaded it, with one infection being prevented for every one or two users. In August 2020, the American Civil Liberties Union (ACLU) argued that there were disparities in smartphone use between demographics and minority groups, and that "even the most comprehensive, all-seeing contact tracing system is of little use without social and medical systems in place to help those who may have the virus — including access to medical care, testing, and support for those who are quarantined." === App store restrictions === Addressing concerns about the spread of misleading or harmful apps, Apple, Google and Amazon set limits on which types of organizations could add coronavirus-related apps to its App Store, limiting them to only "official" or otherwise reputable organizations. === Ethical principles of mass surveillance using COVID-19 contact tracing apps === The advent of COVID-19 contact tracing apps has led to concerns around privacy, the rights of app users, and governmental authority. The European Convention on Human Rights, the International Covenant on Civil and Political Rights (ICCPR) and the United Nations and the Siracusa Principles have outlined 4 principles to consider when looking at the ethical principles of mass surveillance with COVID-19 contact tracing apps. These are necessity, proportionality, scientific validity, and time boundedness. Necessity is defined as the idea that governments should only interfere with a person's rights when deemed essential for public health interests. The potential risks associated with infringements of personal privacy must be outweighed by the possibility of reducing significant harm to others. Potential benefits of contact-tracing apps that may be considered include allowing for blanket population-level quarantine measures to be lifted sooner and the minimization of people under quarantine. Hence, some contend that contact-tracing apps are justified as they may be less intrusive than blanket quarantine measures. Furthermore, the delay of an effective contact-tracing app with significant health and economic benefits may be considered unethical. Proportionality refers to the concept that a contact tracing app's potential negative impact on a person's rights should be justifiable by the severity of the health risks that are being addressed. Apps must use the most privacy-preserving options available to achieve their goals, and the selected option should not only be a logical option for achieving the goal but also an effective one. Scientific validity evaluates whether an app is effective, timely and accurate. Traditional manual contact-tracing procedures are not efficient enough for the COVID-19 pandemic, and do not consider asymptomatic transmission. Contact-tracing apps, on the other hand, can be effective COVID-19 contact-tracing tools that reduce R value to less than 1, leading to sustained epidemic suppression. However, for apps to be effective, there needs to be a minimum 56-60% uptake in the population. Apps should be continually modified to reflect current knowledge on the diseases being monitored. Some argue that contact-tracing apps should be considered societal experimental trials where results and adverse effects are evaluated according to the stringent guidelines of social experiments. Analyses should be conducted by independent research bodies and published for wide dissemination. Despite the current urgency of our pandemic situation, we should still adhere to the standard rigors of scientific evaluation. Time boundedness describe the need for establishing legal and technical sunset clauses so that they are only allowed to operate as long as necessary to address the pandemic situation. Apps should be withdrawn as soon as possible after the end of the pandemic. If the end of the pandemic cannot be predicted, the use of apps should be regularly reviewed and decisions about continued use should be made at each review. Collected data should only be retained by public health authorities for research purposes with clear stipulations on how long the data will be held for and who will be responsible for security, oversight, and ownership. === Privacy, discrimination and marginalisation concerns === The American Civil Liberties Union (ACLU) has published a set of principles for technology-assisted contact tracing and Amnesty International and over 100 other organizations issued a statement calling for limits on this kind of surveillance. The organisations declared eight conditions on governmental projects: surveillance would have to be "lawful, necessary and proportionate"; extensions of monitoring and surveillance would have to have sunset clauses; the use of data would have to be limited to COVID-19 purposes; data security and anonymity would have to be protected and shown to be protected based on evidence; digital surveillance would have to address the risk of exacerbating discrimination and marginalisation; any sharing of data with third parties would have to be defined in law; there would have to be safeguards against abuse and the rights of citizens to respond to abuses; "meaningful participation" by all "relevant stakeholders" would be required, including that of public health experts and marginalised groups. The German Chaos Computer Club (CCC) and Reporters Without Borders also issued checklists. The Exposure Notification service intends to address the problem of persistent surveillance by removing the tracing mechanism from their device operating systems once it is no longer needed. On 20 April 2020, it was reported that over 300 academics had signed a statement favouring decentralised proximity tracing applications over centralised models, given the difficulty in precluding centralised options being used "to enable unwarranted discrimination and surveillance." In a centralised model, a central database records the ID codes of meetings between users. In a decentralised model, this information is recorded on individual phones, with the role of the central

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  JSGF

  JSGF stands for Java Speech Grammar Format or the JSpeech Grammar Format (in a W3C Note). Developed by Sun Microsystems, it is a textual representation of grammars for use in speech recognition for technologies like XHTML+Voice. JSGF adopts the style and conventions of the Java programming language in addition to use of traditional grammar notations. The Speech Recognition Grammar Specification was derived from this specification. == Example == The following JSGF grammar will recognize the words coffee, tea, and milk.

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  Transcription software

  Transcription software assists in the conversion of human speech into a text transcript. Audio or video files can be transcribed manually or automatically. Transcriptionists can replay a recording several times in a transcription editor and type what they hear. By using transcription hot keys, the manual transcription can be accelerated, the sound filtered, equalized or have the tempo adjusted when the clarity is not great. With speech recognition technology, transcriptionists can automatically convert recordings to text transcripts by opening recordings in a PC and uploading them to a cloud for automatic transcription, or transcribe recordings in real-time by using digital dictation. Depending on quality of recordings, machine generated transcripts may still need to be manually verified. The accuracy rate of the automatic transcription depends on several factors such as background noises, speakers' distance to the microphone, and accents. Transcription software, as with transcription services, is often used for business, legal, or medical purposes. Compared with audio content, a text transcript is searchable, takes up less computer memory, and can be used as an alternate method of communication, such as for subtitles and closed captions. Some clinical environments also use digital tools to support transcription workflows, including ambient documentation systems that employ Speech recognition to capture portions of clinical encounters and generate draft notes for later review. These tools are typically used alongside conventional transcription methods. The definition of transcription "software", as compared with transcription "service", is that the former is sufficiently automated that a user can run the entire system without engaging outside personnel. New software-as-a-service and cloud computing models use artificial intelligence, machine learning and natural language processing to convert speech to text and continuously learn new phrases and accents. AI transcription can, however, lead to hallucinations and other errors. == Development == Research at Google released a free android app Google Live Transcribe, it runs on Google Cloud. Google Chrome developed and has an available built in English Live Caption. Google Docs, Google Translate, Google Assistant, GBoard Google Text to Speech engine support transcription tool too. OpenAI launched Whisper, an open-source speech recognition deep learning model in September 2022. In 2024, an AI-powered transcription platform, Transkriptor, was launched, enabling the automatic conversion of audio and video recordings into text using speech recognition technology, with support for transcription in 100 languages and processing of content uploaded via a web interface as well as mobile and browser extensions. It is part of the Tor.app suite of AI-based language processing tools.

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  Plane Finder

  Plane Finder is a United Kingdom-based real-time flight tracking service launched in 2009, that is able to show flight data globally. The data available includes flight numbers, how fast an aircraft is moving, its elevation and destination of travel. Several variants of the service are available as mobile apps including free, premium 3D and augmented reality versions. The flight tracking map and database can be accessed by web browsers. Plane Finder allows registered users to share their ADS-B and MLAT data via the Plane Finder ADS-B Client, available for macOS, Windows and Linux. Plane Finder supports VFR charts from NATS, and was the first major flight tracking app to introduce a replay feature, allowing users to replay flights dating back to 2011. == Flight tracking == Plane Finder collects data from its own global network of receivers, using the following sources. === Automatic dependent surveillance-broadcast (ADS-B) === A network of automatic dependent surveillance-broadcast (ADS-B) receivers gathers aircraft data such as callsign, position and speed. Plane Finder serves to supplement this data with additional information, including aircraft registration/tail number, departure airport, destination, artwork, and photographs. Plane Finder users can apply for an ADS-B receiver in exchange for their flight data. === Multilateration (MLAT) === To deliver aircraft position data where ADS-B is unavailable, Plane Finder uses multilateration (MLAT). Using three or more receivers running Plane Finder client software, monitoring the aircraft simultaneously, the aircraft’s position is calculated using receiver location and accurate timestamps. While European airspace is widely covered, only some parts of North American airspace are covered. === Federal Aviation Administration (FAA) feed === ADS-B is prevalent across Europe and Australia, but not in North America. Where MLAT or ADS-B data is unavailable, a feed from the Federal Aviation Administration provides flight information. The FAA feed covers United States and Canadian airspace, including bordering areas of the Atlantic and Pacific Oceans. === FLARM feed === Plane Finder collects data from a centralised FLARM feed, for monitoring small aircraft and gliders. == Flight data source == The Plane Finder website and database is widely used as an information source to support articles in the media. The Independent used Plane Finder flight tracking to demonstrate to readers the flight path of flight MT2706, which turned back as a result of last minute Egyptian government flight restrictions on 6 November 2015. The Independent also used Plane Finder information to demonstrate a timeline of the speed/altitude of flight 7K 9268, a Russian plane which crashed on 31 October 2015. The BBC cited Plane Finder in regard to the point at which at British Airways flight turned back to Heathrow Airport to make an emergency landing after smoke was seen coming from its engines. Plane Finder data has also been used to create original imagery for the media, such as the Washington Post, which used Plane Finder as a source to show flight patterns immediately after the Brussels bombings in March 2016.

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  PhotoWorks (ray tracing software)

  PhotoWorks is a raytrace rendering program created by Dassault Systèmes SolidWorks Corporation, formerly supplied as a photorealistic rendering add-in for SolidWorks. The program is based on the Mental Ray rendering engine. It has a library of scenes and materials that can be used with user-created SolidWorks files to create still frame images within the SolidWorks GUI. Since the 2011 release of SolidWorks, PhotoWorks has been replaced by the PhotoView 360 rendering utility. A 2010 review comparing PhotoWorks with three other rendering programs for SolidWorks (including PhotoView 360) gave the program high marks for render speed and built-in materials, but low marks for realism and user interface. Appearance File Type: .p2m

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  Automated Lip Reading

  Automated Lip Reading (ALR) is a software technology developed by speech recognition expert Frank Hubner. A video image of a person talking can be analysed by the software. The shapes made by the lips can be examined and then turned into sounds. The sounds are compared to a dictionary to create matches to the words being spoken. The technology was used successfully to analyse silent home movie footage of Adolf Hitler taken by Eva Braun at their Bavarian retreat Berghof. The video, with words, was included in a documentary titled "Hitler's Private World", Revealed Studios, 2006 Source: New Technology catches Hitler off guard

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  Single particle analysis

  Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from TEM images of particulate samples, typically proteins or other large biological entities such as viruses. Individual images of stained or unstained particles are very noisy, making interpretation difficult. Combining several digitized images of similar particles together gives an image with stronger and more easily interpretable features. An extension of this technique uses single particle methods to build up a three-dimensional reconstruction of the particle. Using cryo-electron microscopy it has become possible to generate reconstructions with sub-nanometer, near-atomic resolution resolution first in the case of highly symmetric viruses, and now in smaller, asymmetric proteins as well. == Techniques == Single particle analysis can be done on both negatively stained and vitreous ice-embedded transmission electron cryomicroscopy (CryoTEM) samples. Single particle analysis methods are, in general, reliant on the sample being homogeneous, although techniques for dealing with conformational heterogeneity are being developed. Images (micrographs) are taken with an electron microscope using charged-coupled device (CCD) detectors coupled to a phosphorescent layer (in the past, they were instead collected on film and digitized using high-quality scanners). The image processing is carried out using specialized software programs, often run on multi-processor computer clusters. Depending on the sample or the desired results, various steps of two- or three-dimensional processing can be done. === Alignment and classification === Biological samples, and especially samples embedded in thin vitreous ice, are highly radiation sensitive, thus only low electron doses can be used to image the sample. This low dose, as well as variations in the metal stain used (if used) means images have high noise relative to the signal given by the particle being observed. By aligning several similar images to each other so they are in register and then averaging them, an image with higher signal-to-noise ratio can be obtained. As the noise is mostly randomly distributed and the underlying image features constant, by averaging the intensity of each pixel over several images only the constant features are reinforced. Typically, the optimal alignment (a translation and an in-plane rotation) to map one image onto another is calculated by cross-correlation. However, a micrograph often contains particles in multiple different orientations and/or conformations, and so to get more representative image averages, a method is required to group similar particle images together into multiple sets. This is normally carried out using one of several data analysis and image classification algorithms, such as multi-variate statistical analysis and hierarchical ascendant classification, or k-means clustering. Often data sets of tens of thousands of particle images are used, and to reach an optimal solution an iterative procedure of alignment and classification is used, whereby strong image averages produced by classification are used as reference images for a subsequent alignment of the whole data set. === Image filtering === Image filtering (band-pass filtering) is often used to reduce the influence of high and/or low spatial frequency information in the images, which can affect the results of the alignment and classification procedures. This is particularly useful in negative stain images. The algorithms make use of fast Fourier transforms (FFT), often employing Gaussian shaped soft-edged masks in reciprocal space to suppress certain frequency ranges. High-pass filters remove low spatial frequencies (such as ramp or gradient effects), leaving the higher frequencies intact. Low-pass filters remove high spatial frequency features and have a blurring effect on fine details. === Contrast transfer function === Due to the nature of image formation in the electron microscope, bright-field TEM images are obtained using significant underfocus. This, along with features inherent in the microscope's lens system, creates blurring of the collected images visible as a point spread function. The combined effects of the imaging conditions are known as the contrast transfer function (CTF), and can be approximated mathematically as a function in reciprocal space. Specialized image processing techniques such as phase flipping and amplitude correction / Wiener filtering can (at least partially) correct for the CTF, and allow high resolution reconstructions. === Three-dimensional reconstruction === Transmission electron microscopy images are projections of the object showing the distribution of density through the object, similar to medical X-rays. By making use of the projection-slice theorem a three-dimensional reconstruction of the object can be generated by combining many images (2D projections) of the object taken from a range of viewing angles. Proteins in vitreous ice ideally adopt a random distribution of orientations (or viewing angles), allowing a fairly isotropic reconstruction if a large number of particle images are used. This contrasts with electron tomography, where the viewing angles are limited due to the geometry of the sample/imaging set up, giving an anisotropic reconstruction. Filtered back projection is a commonly used method of generating 3D reconstructions in single particle analysis, although many alternative algorithms exist. Before a reconstruction can be made, the orientation of the object in each image needs to be estimated. Several methods have been developed to work out the relative Euler angles of each image. Some are based on common lines (common 1D projections and sinograms), others use iterative projection matching algorithms. The latter works by beginning with a simple, low resolution 3D starting model and compares the experimental images to projections of the model and creates a new 3D to bootstrap towards a solution. Methods are also available for making 3D reconstructions of helical samples (such as tobacco mosaic virus), taking advantage of the inherent helical symmetry. Both real space methods (treating sections of the helix as single particles) and reciprocal space methods (using diffraction patterns) can be used for these samples. === Tilt methods === The specimen stage of the microscope can be tilted (typically along a single axis), allowing the single particle technique known as random conical tilt. An area of the specimen is imaged at both zero and at high angle (~60-70 degrees) tilts, or in the case of the related method of orthogonal tilt reconstruction, +45 and −45 degrees. Pairs of particles corresponding to the same object at two different tilts (tilt pairs) are selected, and by following the parameters used in subsequent alignment and classification steps a three-dimensional reconstruction can be generated relatively easily. This is because the viewing angle (defined as three Euler angles) of each particle is known from the tilt geometry. 3D reconstructions from random conical tilt suffer from missing information resulting from a restricted range of orientations. Known as the missing cone (due to the shape in reciprocal space), this causes distortions in the 3D maps. However, the missing cone problem can often be overcome by combining several tilt reconstructions. Tilt methods are best suited to negatively stained samples, and can be used for particles that adsorb to the carbon support film in preferred orientations. The phenomenon known as charging or beam-induced movement makes collecting high-tilt images of samples in vitreous ice challenging. === Map visualization and fitting === Various software programs are available that allow viewing the 3D maps. These often enable the user to manually dock in protein coordinates (structures from X-ray crystallography, NMR, or a computational model such as one found in the AlphaFold Protein Structure Database) of subunits into the electron density. Several programs can also fit subunits computationally; as of the 2020s using these programs tend to produce better accuracy than manual docking because they can perform labor-intensive tasks such as: The scale of SPA-derived maps depends on knowing the pixel size (angstorms per pixel), which is not always accurate. Programs can automatically correct for this difference by using coordinate data or by using knowledge of chemical bonds. Many proteins are made up of several roughly rigid protein domains linked by flexible parts. Pre-existing coordinate data, whether experimental or computational, may not exactly match the inter-domain positioning of the cyro-EM map. Modern programs can automatically "chop" pre-existing coordinate data into individual domains and fit them in individually. For higher-resolution structures, it is pos

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  Pattern theory

  Pattern theory, formulated by Ulf Grenander, is a mathematical formalism to describe knowledge of the world as patterns. It differs from other approaches to artificial intelligence in that it does not begin by prescribing algorithms and machinery to recognize and classify patterns; rather, it prescribes a vocabulary to articulate and recast the pattern concepts in precise language. Broad in its mathematical coverage, Pattern Theory spans algebra and statistics, as well as local topological and global entropic properties. In addition to the new algebraic vocabulary, its statistical approach is novel in its aim to: Identify the hidden variables of a data set using real world data rather than artificial stimuli, which was previously commonplace. Formulate prior distributions for hidden variables and models for the observed variables that form the vertices of a Gibbs-like graph. Study the randomness and variability of these graphs. Create the basic classes of stochastic models applied by listing the deformations of the patterns. Synthesize (sample) from the models, not just analyze signals with them. The Brown University Pattern Theory Group was formed in 1972 by Ulf Grenander. Many mathematicians are currently working in this group, noteworthy among them being the Fields Medalist David Mumford. Mumford regards Grenander as his "guru" in Pattern Theory.

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  Tresorit

  Tresorit is a Swiss company providing end-to-end encrypted cloud storage and secure content collaboration services. Founded in 2011, the company primarily serves businesses and organizations with elevated data protection and compliance requirements. Since 2021, Tresorit has been part of Swiss Post's digital business services, which, under the name 'Swiss Post Digital' offer secure communication platforms and connectable software solutions for SMEs, public authorities, and the healthcare sector, among others. == History == Tresorit was founded in 2011 by Hungarian software developers Istvan Lam, Szilveszter Szebeni and Gyorgy Szilagyi with the aim of providing a secure alternative to traditional cloud storage solutions. The company developed a cloud collaboration platform based on client-side end-to-end encryption and a zero-knowledge architecture. In its early years, Tresorit gained attention through a public security challenge inviting researchers to attempt to compromise its encryption system. The initiative received coverage in technology and cybersecurity media. The company initially positioned itself as a secure alternative to conventional cloud storage services and gradually expanded its offering toward enterprise-focused collaboration tools. In 2021, Swiss Post Communications Services acquired a majority stake in Tresorit. The company is now part of Swiss Post, and continues to operate independently within Swiss Post’s digital division, while benefiting from the broader infrastructure and institutional framework of its parent organization. Tresorit has offices in Zurich, Munich, and Budapest. == Products and Services == Tresorit provides a cloud-based platform for secure file storage and collaboration. Its services include encrypted file sharing, email encryption, electronic signatures, and encrypted data rooms for managing sensitive documents and workflows. The platform is available on Windows, macOS, Linux, Android, and iOS. == Technology == Tresorit uses client-side end-to-end encryption based on a zero-knowledge model. Files are encrypted on the user’s device before being uploaded to company servers. According to the company, encryption keys remain under user control, meaning that Tresorit and third parties cannot access the content of stored files. == Security challenge == Between 2013 and 2014, Tresorit organized a public challenge inviting security researchers to attempt to compromise the service's encryption implementation. The challenge received coverage in technology and cybersecurity media. == Acquisition by Swiss Post == In 2021, Swiss Post Communications Services acquired a majority stake in Tresorit as part of Swiss Post’s broader digital services strategy. The company is now part of Swiss Post. == Reception == Tresorit has been covered by international technology and business publications in the context of secure cloud storage and encrypted collaboration services. TechCrunch described the company as an early European provider of end-to-end encrypted cloud services, while The New York Times included it in discussions of secure file-sharing tools. Other publications such as TechRadar and ITPro have reviewed Tresorit in the context of enterprise security and confidential data handling.

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  Voice activity detection

  Voice activity detection (VAD), also known as speech activity detection or speech detection, is the detection of the presence or absence of human speech, used in speech processing. The main uses of VAD are in speaker diarization, speech coding and speech recognition. It can facilitate speech processing, and can also be used to deactivate some processes during non-speech section of an audio session: it can avoid unnecessary coding/transmission of silence packets in Voice over Internet Protocol (VoIP) applications, saving on computation and on network bandwidth. VAD is an important enabling technology for a variety of speech-based applications. Therefore, various VAD algorithms have been developed that provide varying features and compromises between latency, sensitivity, accuracy and computational cost. Some VAD algorithms also provide further analysis, for example whether the speech is voiced, unvoiced or sustained. Voice activity detection is usually independent of language. It was first investigated for use on time-assignment speech interpolation (TASI) systems. == Algorithm overview == The typical design of a VAD algorithm is as follows: There may first be a noise reduction stage, e.g. via spectral subtraction. Then some features or quantities are calculated from a section of the input signal. A classification rule is applied to classify the section as speech or non-speech – often this classification rule finds when a value exceeds a certain threshold. There may be some feedback in this sequence, in which the VAD decision is used to improve the noise estimate in the noise reduction stage, or to adaptively vary the threshold(s). These feedback operations improve the VAD performance in non-stationary noise (i.e. when the noise varies a lot). A representative set of recently published VAD methods formulates the decision rule on a frame by frame basis using instantaneous measures of the divergence distance between speech and noise. The different measures which are used in VAD methods include spectral slope, correlation coefficients, log likelihood ratio, cepstral, weighted cepstral, and modified distance measures. Independently from the choice of VAD algorithm, a compromise must be made between having voice detected as noise, or noise detected as voice (between false positive and false negative). A VAD operating in a mobile phone must be able to detect speech in the presence of a range of very diverse types of acoustic background noise. In these difficult detection conditions it is often preferable that a VAD should fail-safe, indicating speech detected when the decision is in doubt, to lower the chance of losing speech segments. The biggest difficulty in the detection of speech in this environment is the very low signal-to-noise ratios (SNRs) that are encountered. It may be impossible to distinguish between speech and noise using simple level detection techniques when parts of the speech utterance are buried below the noise. == Applications == VAD is an integral part of different speech communication systems such as audio conferencing, echo cancellation, speech recognition, speech encoding, speaker recognition and hands-free telephony. In the field of multimedia applications, VAD allows simultaneous voice and data applications. Similarly, in Universal Mobile Telecommunications Systems (UMTS), it controls and reduces the average bit rate and enhances overall coding quality of speech. In cellular radio systems (for instance GSM and CDMA systems) based on Discontinuous Transmission (DTX) mode, VAD is essential for enhancing system capacity by reducing co-channel interference and power consumption in portable digital devices. In speech processing applications, voice activity detection plays an important role since non-speech frames are often discarded. For a wide range of applications such as digital mobile radio, Digital Simultaneous Voice and Data (DSVD) or speech storage, it is desirable to provide a discontinuous transmission of speech-coding parameters. Advantages can include lower average power consumption in mobile handsets, higher average bit rate for simultaneous services like data transmission, or a higher capacity on storage chips. However, the improvement depends mainly on the percentage of pauses during speech and the reliability of the VAD used to detect these intervals. On the one hand, it is advantageous to have a low percentage of speech activity. On the other hand, clipping, that is the loss of milliseconds of active speech, should be minimized to preserve quality. This is the crucial problem for a VAD algorithm under heavy noise conditions. === Use in telemarketing === One controversial application of VAD is in conjunction with predictive dialers used by telemarketing firms. In order to maximize agent productivity, telemarketing firms set up predictive dialers to call more numbers than they have agents available, knowing most calls will end up in either "Ring – No Answer" or answering machines. When a person answers, they typically speak briefly ("Hello", "Good evening", etc.) and then there is a brief period of silence. Answering machine messages are usually 3–15 seconds of continuous speech. By setting VAD parameters correctly, dialers can determine whether a person or a machine answered the call and, if it's a person, transfer the call to an available agent. If it detects an answering machine message, the dialer hangs up. Often, even when the system correctly detects a person answering the call, no agent may be available, resulting in a "silent call". Call screening with a multi-second message like "please say who you are, and I may pick up the phone" will frustrate such automated calls. == Performance evaluation == To evaluate a VAD, its output using test recordings is compared with those of an "ideal" VAD – created by hand-annotating the presence or absence of voice in the recordings. The performance of a VAD is commonly evaluated on the basis of the following four parameters: FEC (Front End Clipping): clipping introduced in passing from noise to speech activity; MSC (Mid Speech Clipping): clipping due to speech misclassified as noise; OVER: noise interpreted as speech due to the VAD flag remaining active in passing from speech activity to noise; NDS (Noise Detected as Speech): noise interpreted as speech within a silence period. Although the method described above provides useful objective information concerning the performance of a VAD, it is only an approximate measure of the subjective effect. For example, the effects of speech signal clipping can at times be hidden by the presence of background noise, depending on the model chosen for the comfort noise synthesis, so some of the clipping measured with objective tests is in reality not audible. It is therefore important to carry out subjective tests on VADs, the main aim of which is to ensure that the clipping perceived is acceptable. In VoIP applications, front-end clipping can be reduced by rewinding to shortly before the detection and sending very slightly delayed data. This kind of test requires a certain number of listeners to judge recordings containing the processing results of the VADs being tested, giving marks to several speech sequences on the following features: Quality; Comprehension difficulty; Audibility of clipping. These marks are then used to calculate average results for each of the features listed above, thus providing a global estimate of the behavior of the VAD being tested. To conclude, whereas objective methods are very useful in an initial stage to evaluate the quality of a VAD, subjective methods are more significant. As they require the participation of several people for a few days, increasing cost, they are generally only used when a proposal is about to be standardized. == Implementations == One early standard VAD is that developed by British Telecom for use in the Pan-European digital cellular mobile telephone service in 1991. It uses inverse filtering trained on non-speech segments to filter out background noise, so that it can then more reliably use a simple power-threshold to decide if a voice is present. The G.729 standard calculates the following features for its VAD: line spectral frequencies, full-band energy, low-band energy (<1 kHz), and zero-crossing rate. It applies a simple classification using a fixed decision boundary in the space defined by these features, and then applies smoothing and adaptive correction to improve the estimate. The GSM standard includes two VAD options developed by ETSI. Option 1 computes the SNR in nine bands and applies a threshold to these values. Option 2 calculates different parameters: channel power, voice metrics, and noise power. It then thresholds the voice metrics using a threshold that varies according to the estimated SNR. The Speex audio compression library uses a procedure named Improved Minima Controlled Recursive Averaging, which uses a smoothed representation of spectral pow

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