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  Amira (software)

  Amira (ah-MEER-ah) is a software platform for visualization, processing, and analysis of 3D and 4D data. It is being actively developed by Thermo Fisher Scientific in collaboration with the Zuse Institute Berlin (ZIB), and commercially distributed by Thermo Fisher Scientific — together with its sister software Avizo. == Overview == Amira is an extendable software system for scientific visualization, data analysis, and presentation of 3D and 4D data. It is used by researchers and engineers in academia and industry. It is a tool for processing, analysis and visualization of data from various modalities; e.g. micro-CT, PET, Ultrasound. It is used in many fields, such as microscopy in biology and materials science, molecular biology, quantum physics, astrophysics, computational fluid dynamics (CFD), finite element modeling (FEM), non-destructive testing (NDT), and many more. One of the key features, besides data visualization, is Amira's set of tools for image segmentation and geometry reconstruction. This allows the user to mark (or segment) structures and regions of interest in 3D image volumes using automatic, semi-automatic, and manual tools. The segmentation can then be used for a variety of subsequent tasks, such as volumetric analysis, density analysis, shape analysis, or the generation of 3D computer models for visualization, numerical simulations, or rapid prototyping or 3D printing. Other key Amira features are multi-planar and volume visualization, image registration, filament tracing, cell separation and analysis, tetrahedral mesh generation, fiber-tracking from diffusion tensor imaging (DTI) data, skeletonization, spatial graph analysis, and stereoscopic rendering of 3D data over multiple displays and immersive virtual reality environments, including CAVEs. As a commercial product Amira requires the purchase of a license or an academic subscription. A time-limited, but full-featured evaluation version is available for download free of charge. == History == === 1993–1998: Research software === Amira's roots go back to 1993 and the Department for Scientific Visualization, headed by Hans-Christian Hege at the Zuse Institute Berlin (ZIB). The ZIB is a research institute for mathematics and informatics. The Scientific Visualization department's mission is to help solve computationally and scientifically challenging tasks in medicine, biology, engineering and materials science. For this purpose, it develops algorithms and software for 2D, 3D, and 4D data visualization and visually supported exploration and analysis. At that time, the young visualization group at the ZIB had experience with the extendable, data flow-oriented visualization environments apE, IRIS Explorer, and Advanced Visualization Studio (AVS), but was not satisfied with these products' interactivity, flexibility, and ease-of-use for non-computer scientists. Therefore, the development of a new software system was started in a research project within a medically oriented, multi-disciplinary collaborative research center. Based on experiences that Tobias Höllerer had gained in late 1993 with the new graphics library IRIS Inventor, it was decided to utilize that library. The development of the medical planning system was performed by Detlev Stalling, who later became the chief software architect of Amira. The new software was called "HyperPlan", highlighting its initial target application – a planning system for hyperthermia cancer treatment. The system was being developed on Silicon Graphics (SGI) computers, which at the time were the standard workstations used for high-end graphics computing. The software was based on libraries such as OpenGL (originally IRIS GL), Open Inventor (originally IRIS Inventor), and the graphical user interface libraries X11, Motif (software), and ViewKit. In 1998, X11/Motif/Viewkit were replaced by the Qt toolkit. The HyperPlan framework served as the base for more and more projects at the ZIB and was used by a growing number of researchers in collaborating institutions. The projects included applications in medical image computing, medical visualization, neurobiology, confocal microscopy, flow visualization, molecular analytics and computational astrophysics. === 1998–today: Commercially supported product === The growing number of users of the system started to exceed the capacities that ZIB could spare for software distribution and support, as ZIB's primary mission was algorithmic research. Therefore, the spin-off company Indeed – Visual Concepts GmbH was founded by Hans-Christian Hege, Detlev Stalling, and Malte Westerhoff. In Feb 1998 the HyperPlan software was given the new, application-neutral name "Amira". This name is not an acronym, but was chosen for being pronounceable in different languages and providing a suitable connotation, namely "to look at" or "to wonder at", from the Latin verb "admirare" (to admire), which reflects a basic situation in data visualization. A major re-design of the software was undertaken by Detlev Stalling and Malte Westerhoff in order to make it a commercially supportable product and to make it available on non-SGI computers as well. In March 1999, the first version of the commercial Amira was exhibited at the CeBIT tradeshow in Hannover, Germany on SGI IRIX and Hewlett-Packard UniX (HP-UX) booths. Versions for Linux and Microsoft Windows followed within the following twelve months. Later Mac OS X support was added. Indeed – Visual Concepts GmbH selected the Bordeaux, France and San Diego, United States based company TGS, Inc. as the worldwide distributor for Amira and completed five major releases (up to version 3.1) in the subsequent four years. In 2003 both Indeed – Visual Concepts GmbH, as well as TGS, Inc. were acquired by Massachusetts-based Mercury Computer Systems, Inc. (NASDAQ:MRCY) and became part of Mercury's newly formed life sciences business unit, later branded Visage Imaging. In 2009, Mercury Computer Systems, Inc. spun off Visage Imaging again and sold it to Melbourne, Australia based Promedicus Ltd (ASX:PME), a leading provider of radiology information systems and medical IT solutions. During this time, Amira continued to be developed in Berlin, Germany and in close collaboration with the ZIB, still headed by the original creators of Amira. TGS, located in Bordeaux, France was sold by Mercury Computer systems to a French investor and renamed to Visualization Sciences Group (VSG). VSG continued the work on a complementary product named Avizo, based on the same source code but customized for material sciences. In August 2012, FEI, to that date the largest OEM reseller of Amira, purchased VSG and the Amira business from Promedicus. This brought the two software sisters Amira and Avizo back into one hand. In August 2013, Visualization Sciences Group (VSG) became a business unit of FEI. In 2016 FEI has been bought by Thermo Fisher Scientific and became part of its Materials & Structural Analysis division in early 2017. Amira and Avizo are still being marketed as two different products; Amira for life sciences and Avizo for materials science, but the development efforts are now joined once again. In the meantime, the number of scientific articles using the Amira / Avizo software, is in the order of 10 thousands. == Amira options == === Microscopy option === Specific readers for microscopy data Image deconvolution Exploration of 3D imagery obtained from virtually any microscope Extraction and editing of filament networks from microscopy images === DICOM reader === Import of clinical and preclinical data in DICOM format === Mesh option === Generation of 3D finite element (FE) meshes from segmented image data Support for many state-of-the-art FE solver formats High-quality visualization of simulation mesh-based results, using scalar, vector, and tensor field display modules === Skeletonization option === Reconstruction and analysis of neural and vascular networks Visualization of skeletonized networks Length and diameter quantification of network segments Ordering of segments in a tree graph Skeletonization of very large image stacks === Molecular option === Advanced tools for the visualization of molecule models Hardware-accelerated volume rendering Powerful molecule editor Specific tools for complex molecular visualization === Developer option === Creation of new custom components for visualizing or data processing Implementation of new file readers or writers C++ programming language Development wizard for getting started quickly === Neuro option === Medical image analysis for DTI and brain perfusion Fiber tracking supporting several stream-line based algorithms Fiber separation into fiber bundles based on user defined source and destination regions Computation of tensor fields, diffusion weighted maps Eigenvalue decomposition of tensor fields Computation of mean transit time, cerebral blood flow, and cerebral blood volume === VR option === Visualization of data on large tiled displays

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  Harrison White

  Harrison Colyar White (March 21, 1930 – May 18, 2024) was an American sociologist who was the Giddings Professor of Sociology at Columbia University. White played an influential role in the “Harvard Revolution” in social networks and the New York School of relational sociology. He is credited with the development of a number of mathematical models of social structure including vacancy chains and blockmodels. He has been a leader of a revolution in sociology that is still in process, using models of social structure that are based on patterns of relations instead of the attributes and attitudes of individuals. Among social network researchers, White is widely respected. For instance, at the 1997 International Network of Social Network Analysis conference, the organizer held a special “White Tie” event, dedicated to White. Social network researcher Emmanuel Lazega refers to him as both “Copernicus and Galileo” because he invented both the vision and the tools. The most comprehensive documentation of his theories can be found in the book Identity and Control, first published in 1992. A major rewrite of the book appeared in June 2008. In 2011, White received the W.E.B. DuBois Career of Distinguished Scholarship Award from the American Sociological Association, which honors "scholars who have shown outstanding commitment to the profession of sociology and whose cumulative work has contributed in important ways to the advancement of the discipline." Before his retirement to live in Tucson, Arizona, White was interested in sociolinguistics and business strategy as well as sociology. == Life and career == === Early years === White was born on March 21, 1930, in Washington, D.C. He had three siblings and his father was a doctor in the US Navy. Although moving around to different Naval bases throughout his adolescence, he considered himself Southern, and Nashville, TN to be his home. At the age of 15, he entered the Massachusetts Institute of Technology (MIT), receiving his undergraduate degree at 20 years of age; five years later, in 1955, he received a doctorate in theoretical physics, also from MIT with John C. Slater as his advisor. His dissertation was titled A quantum-mechanical calculation of inter-atomic force constants in copper. This was published in the Physical Review as "Atomic Force Constants of Copper from Feynman's Theorem" (1958). While at MIT he also took a course with the political scientist Karl Deutsch, who White credits with encouraging him to move toward the social sciences. === Princeton University === After receiving his PhD in theoretical physics, he received a Fellowship from the Ford Foundation to begin his second doctorate in sociology at Princeton University. His dissertation advisor was Marion J. Levy. White also worked with Wilbert Moore, Fred Stephan, and Frank W. Notestein while at Princeton. His cohort was very small, with only four or five other graduate students including David Matza, and Stanley Udy. At the same time, he took up a position as an operations analyst at the Operations Research Office, Johns Hopkins University from 1955 to 1956. During this period, he worked with Lee S. Christie on Queuing with Preemptive Priorities or with Breakdown, which was published in 1958. Christie previously worked alongside mathematical psychologist R. Duncan Luce in the Small Group Laboratory at MIT while White was completing his first PhD in physics also at MIT. While continuing his studies at Princeton, White also spent a year as a fellow at the Center for Advanced Study in the Behavioral Sciences, Stanford University, California where he met Harold Guetzkow. Guetzkow was a faculty member at the Carnegie Institute of Technology, known for his application of simulations to social behavior and long-time collaborator with many other pioneers in organization studies, including Herbert A. Simon, James March, and Richard Cyert. Upon meeting Simon through his mutual acquaintance with Guetzkow, White received an invitation to move from California to Pittsburgh to work as an assistant professor of Industrial Administration and Sociology at the Graduate School of Industrial Administration, Carnegie Institute of Technology (later Carnegie-Mellon University), where he stayed for a couple of years, between 1957 and 1959. In an interview, he claimed to have fought with the dean, Leyland Bock, to have the word "sociology" included in his title. It was also during his time at the Stanford Center for Advanced Study that White met his first wife, Cynthia A. Johnson, who was a graduate of Radcliffe College, where she had majored in art history. The couple's joint work on the French Impressionists, Canvases and Careers (1965) and “Institutional Changes in the French Painting World” (1964), originally grew out of a seminar on art in 1957 at the Center for Advanced Study led by Robert Wilson. White originally hoped to use sociometry to map the social structure of French art to predict shifts, but he had an epiphany that it was not social structure but institutional structure which explained the shift. It was also during these years that White, still a graduate student in sociology, wrote and published his first social scientific work, "Sleep: A Sociological Interpretation" in Acta Sociologica in 1960, together with Vilhelm Aubert, a Norwegian sociologist. This work was a phenomenological examination of sleep which attempted to "demonstrate that sleep was more than a straightforward biological activity... [but rather also] a social event". For his dissertation, White carried out empirical research on a research and development department in a manufacturing firm, consisting of interviews and a 110-item questionnaire with managers. He specifically used sociometric questions, which he used to model the "social structure" of relationships between various departments and teams in the organization. In May 1960 he submitted as his doctoral dissertation, titled Research and Development as a Pattern in Industrial Management: A Case Study in Institutionalisation and Uncertainty, earning a PhD in sociology from Princeton University. His first publication based on his dissertation was ''Management conflict and sociometric structure'' in the American Journal of Sociology. === University of Chicago === In 1959 James Coleman left the University of Chicago to found a new department of social relations at Johns Hopkins University, this left a vacancy open for a mathematical sociologist like White. He moved to Chicago to start working as an associate professor at the Department of Sociology. At that time, highly influential sociologists, such as Peter Blau, Mayer Zald, Elihu Katz, Everett Hughes, Erving Goffman were there. As Princeton only required one year in residence, and White took the opportunity to take positions at Johns Hopkins, Stanford, and Carnegie while still working on his dissertation, it was at Chicago that White credits as being his "real socialization in a way, into sociology." It was here that White advised his first two graduate students Joel H. Levine and Morris Friedell, both who went on to make contributions to social network analysis in sociology. While at the Center for Advanced Study, White began learning anthropology and became fascinated with kinship. During his stay at the University of Chicago White was able to finish An Anatomy of Kinship, published in 1963 within the Prentice-Hall series in Mathematical Analysis of Social Behavior, with James Coleman and James March as chief editors. The book received significant attention from many mathematical sociologists of the time, and contributed greatly to establish White as a model builder. === The Harvard Revolution === In 1963, White left Chicago to be an associate professor of sociology at the Harvard Department of Social Relations—the same department founded by Talcott Parsons and still heavily influenced by the structural-functionalist paradigm of Parsons. As White previously only taught graduate courses at Carnegie and Chicago, his first undergraduate course was An Introduction to Social Relations (see Influence) at Harvard, which became infamous among network analysts. As he "thought existing textbooks were grotesquely unscientific," the syllabus of the class was noted for including few readings by sociologists, and comparatively more readings by anthropologists, social psychologists, and historians. White was also a vocal critic of what he called the "attributes and attitudes" approach of Parsonsian sociology, and came to be the leader of what has been variously known as the “Harvard Revolution," the "Harvard breakthrough," or the "Harvard renaissance" in social networks. He worked closely with small group researchers George C. Homans and Robert F. Bales, which was largely compatible with his prior work in organizational research and his efforts to formalize network analysis. Overlapping White's early years, Charles Tilly, a graduate of the Harvard Department of Social

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  TabPFN

  TabPFN (Tabular Prior-data Fitted Network) is a machine learning model for tabular datasets proposed in 2022. It uses a transformer architecture. It is intended for supervised classification and regression analysis on tabular datasets, particularly focusing on small- to medium-sized datasets. The latest version, TabPFN-3, was released in May 2026 and supports datasets with up to one million rows and 200 features. == History == TabPFN was first introduced in a 2022 pre-print and presented at ICLR 2023. TabPFN v2 was published in 2025 in Nature by Hollmann and co-authors. The source code is published on GitHub under a modified Apache License and on PyPi. Writing for ICLR blogs, McCarter states that the model has attracted attention due to its performance on small dataset benchmarks. TabPFN v2.5 was released on November 6, 2025. TabPFN-3 was released on May 12, 2026. Prior Labs, founded in 2024, aims to commercialize TabPFN. As of April 2026, the open-source TabPFN repository had more than 6,000 stars on GitHub. == Overview and pre-training == TabPFN supports classification, regression and generative tasks. It leverages "Prior-Data Fitted Networks" models to model tabular data. By using a transformer pre-trained on synthetic tabular datasets, TabPFN avoids benchmark contamination and costs of curating real-world data. TabPFN v2 was pre-trained on approximately 130 million such datasets. Synthetic datasets are generated using causal models or Bayesian neural networks; this can include simulating missing values, imbalanced data, and noise. Random inputs are passed through these models to generate outputs, with a bias towards simpler causal structures. During pre-training, TabPFN predicts the masked target values of new data points given training data points and their known targets, effectively learning a generic learning algorithm that is executed by running a neural network forward pass. The new dataset is then processed in a single forward pass without retraining. The model's transformer encoder processes features and labels by alternating attention across rows and columns. TabPFN v2 handles numerical and categorical features, missing values, and supports tasks like regression and synthetic data generation, while TabPFN-2.5 scales this approach to datasets with up to 50,000 rows and 2,000 features. TabPFN-3 introduced a redesigned architecture with row-compression, an attention-based many-class decoder, native missing-value handling, and inference optimizations such as row chunking and a reduced key-value cache, with benchmark-validated regimes of up to 1 million rows with 200 features, 100,000 rows with 2,000 features, or 1,000 rows with 20,000 features. Since TabPFN is pre-trained, in contrast to other deep learning methods, it does not require costly hyperparameter optimization. == Research == TabPFN is the subject of on-going research. Applications for TabPFN have been investigated for domains such as chemoproteomics, insurance risk classification, and metagenomics. In clinical research, TabPFN was used in a study on the early detection of pancreatic cancer from blood samples, where it was combined with metabolomic data and reported high diagnostic performance. == Applications == TabPFN has been used in industrial and biomedical contexts. Hitachi Ltd. has been reported to use the model for predictive maintenance in rail networks, with its use described as helping to identify track issues earlier and reduce manual inspections. In the biomedical domain, Oxford Cancer Analytics has used TabPFN in the analysis of proteomic data in lung disease research. A 2025 ML Contests report noted that the winners of DrivenData's PREPARE challenge used TabPFN to generate features for gradient-boosted decision tree models. == Limitations == TabPFN has been criticized for its "one large neural network is all you need" approach to modeling problems. Further, its performance is limited in high-dimensional and large-scale datasets. == Scaling Mode == In late November 2025, Prior Labs introduced ‘‘Scaling Mode’’, an operating mode for TabPFN designed to remove the fixed upper bound on training set size. Earlier versions of TabPFN had been optimized and validated primarily for datasets of up to 100,000 rows, whereas Scaling Mode was reported to extend support to substantially larger datasets, with benchmarked experiments on datasets containing up to 10 million rows. According to Prior Labs, Scaling Mode preserves the existing TabPFN architecture, including its alternating row-attention and column-attention design, as well as the same feature-count limits as prior releases. Inference remains based on a single forward pass rather than dataset-specific gradient-descent training, while scalability is described as being constrained primarily by available compute and memory resources. Prior Labs reported benchmark results on an internal collection of datasets ranging from 1 million to 10 million rows across industry and scientific applications. In these benchmarks, Scaling Mode was compared with CatBoost, XGBoost, LightGBM, and TabPFN 2.5 using 50,000-row subsampling. The company stated that predictive performance improved monotonically with increasing training set size and that no diminishing returns from scaling were observed within the tested range. Prior Labs also announced the release through company and executive social media channels. TabPFN-3 later incorporated related scaling improvements, including row chunking and a reduced key-value cache, into the model architecture and inference pipeline.

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  Aleph (ILP)

  Aleph (A Learning Engine for Proposing Hypotheses) is an inductive logic programming system introduced by Ashwin Srinivasan in 2001. As of 2022 it is still one of the most widely used inductive logic programming systems. It is based on the earlier system Progol. == Learning task == The input to Aleph is background knowledge, specified as a logic program, a language bias in the form of mode declarations, as well as positive and negative examples specified as ground facts. As output it returns a logic program which, together with the background knowledge, entails all of the positive examples and none of the negative examples. == Basic algorithm == Starting with an empty hypothesis, Aleph proceeds as follows: It chooses a positive example to generalise; if none are left, it aborts and outputs the current hypothesis. Then it constructs the bottom clause, that is, the most specific clause that is allowed by the mode declarations and covers the example. It then searches for a generalisation of the bottom clause that scores better on the chosen metric. It then adds the new clause to the hypothesis program and removes all examples that are covered by the new clause. == Search algorithm == Aleph searches for clauses in a top-down manner, using the bottom clause constructed in the preceding step to bound the search from below. It searches the refinement graph in a breadth-first manner, with tunable parameters to bound the maximal clause size and proof depth. It scores each clause using one of 13 different evaluation metrics, as chosen in advance by the user.

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  SAP StreamWork

  SAP StreamWork is an enterprise collaboration tool from SAP SE released in March 2010, and discontinued in December 2015. StreamWork allowed real-time collaboration like Google Wave, but focused on business activities such as analyzing data, planning meetings, and making decisions. It incorporated technology from Box.net and Evernote to allow users to connect to online files and documents, and document-reader technology from Scribd allowed users to view documents directly within its environment. StreamWork supported the OpenSocial set of application programming interfaces (APIs), allowing it to connect to tools built by third-party developers, such as Google Docs. A version of StreamWork intended for large enterprises used a virtual appliance based on Novell's SUSE Linux Enterprise to connect it to business systems, including those from SAP.

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  Confirmatory blockmodeling

  Confirmatory blockmodeling is a deductive approach in blockmodeling, where a blockmodel (or part of it) is prespecify before the analysis, and then the analysis is fit to this model. When only a part of analysis is prespecify (like individual cluster(s) or location of the block types), it is called partially confirmatory blockmodeling. This is so-called indirect approach, where the blockmodeling is done on the blockmodel fitting (e.g., a priori hypothesized blockmodel). Opposite approach to the confirmatory blockmodeling is an inductive exploratory blockmodeling.

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  Alternating decision tree

  An alternating decision tree (ADTree) is a machine learning method for classification. It generalizes decision trees and has connections to boosting. An ADTree consists of an alternation of decision nodes, which specify a predicate condition, and prediction nodes, which contain a single number. An instance is classified by an ADTree by following all paths for which all decision nodes are true, and summing any prediction nodes that are traversed. == History == ADTrees were introduced by Yoav Freund and Llew Mason. However, the algorithm as presented had several typographical errors. Clarifications and optimizations were later presented by Bernhard Pfahringer, Geoffrey Holmes and Richard Kirkby. Implementations are available in Weka and JBoost. == Motivation == Original boosting algorithms typically used either decision stumps or decision trees as weak hypotheses. As an example, boosting decision stumps creates a set of T {\displaystyle T} weighted decision stumps (where T {\displaystyle T} is the number of boosting iterations), which then vote on the final classification according to their weights. Individual decision stumps are weighted according to their ability to classify the data. Boosting a simple learner results in an unstructured set of T {\displaystyle T} hypotheses, making it difficult to infer correlations between attributes. Alternating decision trees introduce structure to the set of hypotheses by requiring that they build off a hypothesis that was produced in an earlier iteration. The resulting set of hypotheses can be visualized in a tree based on the relationship between a hypothesis and its "parent." Another important feature of boosted algorithms is that the data is given a different distribution at each iteration. Instances that are misclassified are given a larger weight while accurately classified instances are given reduced weight. == Alternating decision tree structure == An alternating decision tree consists of decision nodes and prediction nodes. Decision nodes specify a predicate condition. Prediction nodes contain a single number. ADTrees always have prediction nodes as both root and leaves. An instance is classified by an ADTree by following all paths for which all decision nodes are true and summing any prediction nodes that are traversed. This is different from binary classification trees such as CART (Classification and regression tree) or C4.5 in which an instance follows only one path through the tree. === Example === The following tree was constructed using JBoost on the spambase dataset (available from the UCI Machine Learning Repository). In this example, spam is coded as 1 and regular email is coded as −1. The following table contains part of the information for a single instance. The instance is scored by summing all of the prediction nodes through which it passes. In the case of the instance above, the score is calculated as The final score of 0.657 is positive, so the instance is classified as spam. The magnitude of the value is a measure of confidence in the prediction. The original authors list three potential levels of interpretation for the set of attributes identified by an ADTree: Individual nodes can be evaluated for their own predictive ability. Sets of nodes on the same path may be interpreted as having a joint effect The tree can be interpreted as a whole. Care must be taken when interpreting individual nodes as the scores reflect a re weighting of the data in each iteration. == Description of the algorithm == The inputs to the alternating decision tree algorithm are: A set of inputs ( x 1 , y 1 ) , … , ( x m , y m ) {\displaystyle (x_{1},y_{1}),\ldots ,(x_{m},y_{m})} where x i {\displaystyle x_{i}} is a vector of attributes and y i {\displaystyle y_{i}} is either -1 or 1. Inputs are also called instances. A set of weights w i {\displaystyle w_{i}} corresponding to each instance. The fundamental element of the ADTree algorithm is the rule. A single rule consists of a precondition, a condition, and two scores. A condition is a predicate of the form "attribute value." A precondition is simply a logical conjunction of conditions. Evaluation of a rule involves a pair of nested if statements: 1 if (precondition) 2 if (condition) 3 return score_one 4 else 5 return score_two 6 end if 7 else 8 return 0 9 end if Several auxiliary functions are also required by the algorithm: W + ( c ) {\displaystyle W_{+}(c)} returns the sum of the weights of all positively labeled examples that satisfy predicate c {\displaystyle c} W − ( c ) {\displaystyle W_{-}(c)} returns the sum of the weights of all negatively labeled examples that satisfy predicate c {\displaystyle c} W ( c ) = W + ( c ) + W − ( c ) {\displaystyle W(c)=W_{+}(c)+W_{-}(c)} returns the sum of the weights of all examples that satisfy predicate c {\displaystyle c} The algorithm is as follows: 1 function ad_tree 2 input Set of m training instances 3 4 wi = 1/m for all i 5 a = 1 2 ln W + ( t r u e ) W − ( t r u e ) {\displaystyle a={\frac {1}{2}}{\textrm {ln}}{\frac {W_{+}(true)}{W_{-}(true)}}} 6 R0 = a rule with scores a and 0, precondition "true" and condition "true." 7 P = { t r u e } {\displaystyle {\mathcal {P}}=\{true\}} 8 C = {\displaystyle {\mathcal {C}}=} the set of all possible conditions 9 for j = 1 … T {\displaystyle j=1\dots T} 10 p ∈ P , c ∈ C {\displaystyle p\in {\mathcal {P}},c\in {\mathcal {C}}} get values that minimize z = 2 ( W + ( p ∧ c ) W − ( p ∧ c ) + W + ( p ∧ ¬ c ) W − ( p ∧ ¬ c ) ) + W ( ¬ p ) {\displaystyle z=2\left({\sqrt {W_{+}(p\wedge c)W_{-}(p\wedge c)}}+{\sqrt {W_{+}(p\wedge \neg c)W_{-}(p\wedge \neg c)}}\right)+W(\neg p)} 11 P + = p ∧ c + p ∧ ¬ c {\displaystyle {\mathcal {P}}+=p\wedge c+p\wedge \neg c} 12 a 1 = 1 2 ln W + ( p ∧ c ) + 1 W − ( p ∧ c ) + 1 {\displaystyle a_{1}={\frac {1}{2}}{\textrm {ln}}{\frac {W_{+}(p\wedge c)+1}{W_{-}(p\wedge c)+1}}} 13 a 2 = 1 2 ln W + ( p ∧ ¬ c ) + 1 W − ( p ∧ ¬ c ) + 1 {\displaystyle a_{2}={\frac {1}{2}}{\textrm {ln}}{\frac {W_{+}(p\wedge \neg c)+1}{W_{-}(p\wedge \neg c)+1}}} 14 Rj = new rule with precondition p, condition c, and weights a1 and a2 15 w i = w i e − y i R j ( x i ) {\displaystyle w_{i}=w_{i}e^{-y_{i}R_{j}(x_{i})}} 16 end for 17 return set of Rj The set P {\displaystyle {\mathcal {P}}} grows by two preconditions in each iteration, and it is possible to derive the tree structure of a set of rules by making note of the precondition that is used in each successive rule. == Empirical results == Figure 6 in the original paper demonstrates that ADTrees are typically as robust as boosted decision trees and boosted decision stumps. Typically, equivalent accuracy can be achieved with a much simpler tree structure than recursive partitioning algorithms.

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  Latent and observable variables

  In statistics, latent variables (from Latin: present participle of lateo 'lie hidden') are variables that can only be inferred indirectly through a mathematical model from other observable variables that can be directly observed or measured. Such latent variable models are used in many disciplines, including engineering, medicine, ecology, physics, machine learning/artificial intelligence, natural language processing, bioinformatics, chemometrics, demography, economics, management, political science, psychology and the social sciences. Latent variables may correspond to aspects of physical reality. These could in principle be measured, but may not be for practical reasons. Among the earliest expressions of this idea is Francis Bacon's polemic the Novum Organum, itself a challenge to the more traditional logic expressed in Aristotle's Organon: But the latent process of which we speak, is far from being obvious to men’s minds, beset as they now are. For we mean not the measures, symptoms, or degrees of any process which can be exhibited in the bodies themselves, but simply a continued process, which, for the most part, escapes the observation of the senses. In this situation, the term hidden variables is commonly used, reflecting the fact that the variables are meaningful, but not observable. Other latent variables correspond to abstract concepts, like categories, behavioral or mental states, or data structures. The terms hypothetical variables or hypothetical constructs may be used in these situations. The use of latent variables can serve to reduce the dimensionality of data. Many observable variables can be aggregated in a model to represent an underlying concept, making it easier to understand the data. In this sense, they serve a function similar to that of scientific theories. At the same time, latent variables link observable "sub-symbolic" data in the real world to symbolic data in the modeled world. == Examples == === Psychology === Latent variables, as created by factor analytic methods, generally represent "shared" variance, or the degree to which variables "move" together. Variables that have no correlation cannot result in a latent construct based on the common factor model. The "Big Five personality traits" have been inferred using factor analysis. extraversion spatial ability wisdom: “Two of the more predominant means of assessing wisdom include wisdom-related performance and latent variable measures.” Spearman's g, or the general intelligence factor in psychometrics === Economics === Examples of latent variables from the field of economics include quality of life, business confidence, morale, happiness and conservatism: these are all variables which cannot be measured directly. However, by linking these latent variables to other, observable variables, the values of the latent variables can be inferred from measurements of the observable variables. Quality of life is a latent variable which cannot be measured directly, so observable variables are used to infer quality of life. Observable variables to measure quality of life include wealth, employment, environment, physical and mental health, education, recreation and leisure time, and social belonging. === Medicine === Latent-variable methodology is used in many branches of medicine. A class of problems that naturally lend themselves to latent variables approaches are longitudinal studies where the time scale (e.g. age of participant or time since study baseline) is not synchronized with the trait being studied. For such studies, an unobserved time scale that is synchronized with the trait being studied can be modeled as a transformation of the observed time scale using latent variables. Examples of this include disease progression modeling and modeling of growth (see box). == Inferring latent variables == There exists a range of different model classes and methodology that make use of latent variables and allow inference in the presence of latent variables. Models include: linear mixed-effects models and nonlinear mixed-effects models Hidden Markov models Factor analysis Item response theory Analysis and inference methods include: Principal component analysis Instrumented principal component analysis Partial least squares regression Latent semantic analysis and probabilistic latent semantic analysis EM algorithms Metropolis–Hastings algorithm === Bayesian algorithms and methods === Bayesian statistics is often used for inferring latent variables. Latent Dirichlet allocation The Chinese restaurant process is often used to provide a prior distribution over assignments of objects to latent categories. The Indian buffet process is often used to provide a prior distribution over assignments of latent binary features to objects.

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  Collaboration-oriented architecture

  Collaboration Oriented Architecture (COA) is a computer system that is designed to collaborate, or use services, from systems that are outside of the operators control. Collaboration Oriented Architecture will often use Service Oriented Architecture to deliver the technical framework. Collaboration Oriented Architecture is the ability to collaborate between systems that are based on the Jericho Forum principles or "Commandments". Bill Gates and Craig Mundie (Microsoft) clearly articulated the need for people to work outside of their organizations in a secure and collaborative manner in their opening keynote to the RSA Security Conference in February 2007. Successful implementation of a Collaboration Oriented Architecture implies the ability to successfully inter-work securely over the Internet and will typically mean the resolution of the problems that come with de-perimeterisation. == Etymology == The term Collaboration Oriented Architectures was defined and developed in a meeting of the Jericho Forum at a meeting held at HSBC on 6 July 2007. == Definition == The key elements that qualify a security architecture as a Collaboration Oriented Architecture are as follows; Protocol: Systems use appropriately secure protocols to communicate. Authentication: The protocol is authenticated with user and/or system credentials. Federation: User and/or systems credentials are accepted and validated by systems that are not under your (locus of) control. Network Agnostic: The design does not rely on a secure network, thus it will operate securely from an Intranet to raw-Internet Trust: The collaborating system have the capacity to be able to confirm to a specified degree of confidence that the components in a transaction chain have. Risk: The collaborating systems can make a risk assessment on any transaction based on the communicated levels of required trust, based on the required degree of identity, confidentiality, integrity, availability. == Authentication == Working in a collaborative multi-sourced environment implies the need for authentication, authorization and accountability which must interoperate / exchange outside of your locus / area of control. People/systems must be able to manage permissions of resources and rights of users they don't control There must be capability of trusting an organization, which can authenticate individuals or groups, thus eliminating the need to create separate identities In principle, only one instance of person / system / identity may exist, but privacy necessitates the support for multiple instances, or one instance with multiple facets, often referred to as personas Systems must be able to pass on security credentials /assertions Multiple loci (areas) of control must be supported

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  Triplet loss

  Triplet loss is a machine learning loss function widely used in one-shot learning, a setting where models are trained to generalize effectively from limited examples. It was conceived by Google researchers for their prominent FaceNet algorithm for face detection. Triplet loss is designed to support metric learning. Namely, to assist training models to learn an embedding (mapping to a feature space) where similar data points are closer together and dissimilar ones are farther apart, enabling robust discrimination across varied conditions. In the context of face detection, data points correspond to images. == Definition == The loss function is defined using triplets of training points of the form ( A , P , N ) {\displaystyle (A,P,N)} . In each triplet, A {\displaystyle A} (called an "anchor point") denotes a reference point of a particular identity, P {\displaystyle P} (called a "positive point") denotes another point of the same identity in point A {\displaystyle A} , and N {\displaystyle N} (called a "negative point") denotes a point of an identity different from the identity in point A {\displaystyle A} and P {\displaystyle P} . Let x {\displaystyle x} be some point and let f ( x ) {\displaystyle f(x)} be the embedding of x {\displaystyle x} in the finite-dimensional Euclidean space. It shall be assumed that the L2-norm of f ( x ) {\displaystyle f(x)} is unity (the L2 norm of a vector X {\displaystyle X} in a finite dimensional Euclidean space is denoted by ‖ X ‖ {\displaystyle \Vert X\Vert } .) We assemble m {\displaystyle m} triplets of points from the training dataset. The goal of training here is to ensure that, after learning, the following condition (called the "triplet constraint") is satisfied by all triplets ( A ( i ) , P ( i ) , N ( i ) ) {\displaystyle (A^{(i)},P^{(i)},N^{(i)})} in the training data set: ‖ f ( A ( i ) ) − f ( P ( i ) ) ‖ 2 2 + α < ‖ f ( A ( i ) ) − f ( N ( i ) ) ‖ 2 2 {\displaystyle \Vert f(A^{(i)})-f(P^{(i)})\Vert _{2}^{2}+\alpha <\Vert f(A^{(i)})-f(N^{(i)})\Vert _{2}^{2}} The variable α {\displaystyle \alpha } is a hyperparameter called the margin, and its value must be set manually. In the FaceNet system, its value was set as 0.2. Thus, the full form of the function to be minimized is the following: L = ∑ i = 1 m max ( ‖ f ( A ( i ) ) − f ( P ( i ) ) ‖ 2 2 − ‖ f ( A ( i ) ) − f ( N ( i ) ) ‖ 2 2 + α , 0 ) {\displaystyle L=\sum _{i=1}^{m}\max {\Big (}\Vert f(A^{(i)})-f(P^{(i)})\Vert _{2}^{2}-\Vert f(A^{(i)})-f(N^{(i)})\Vert _{2}^{2}+\alpha ,0{\Big )}} == Intuition == A baseline for understanding the effectiveness of triplet loss is the contrastive loss, which operates on pairs of samples (rather than triplets). Training with the contrastive loss pulls embeddings of similar pairs closer together, and pushes dissimilar pairs apart. Its pairwise approach is greedy, as it considers each pair in isolation. Triplet loss innovates by considering relative distances. Its goal is that the embedding of an anchor (query) point be closer to positive points than to negative points (also accounting for the margin). It does not try to further optimize the distances once this requirement is met. This is approximated by simultaneously considering two pairs (anchor-positive and anchor-negative), rather than each pair in isolation. == Triplet "mining" == One crucial implementation detail when training with triplet loss is triplet "mining", which focuses on the smart selection of triplets for optimization. This process adds an additional layer of complexity compared to contrastive loss. A naive approach to preparing training data for the triplet loss involves randomly selecting triplets from the dataset. In general, the set of valid triplets of the form ( A ( i ) , P ( i ) , N ( i ) ) {\displaystyle (A^{(i)},P^{(i)},N^{(i)})} is very large. To speed-up training convergence, it is essential to focus on challenging triplets. In the FaceNet paper, several options were explored, eventually arriving at the following. For each anchor-positive pair, the algorithm considers only semi-hard negatives. These are negatives that violate the triplet requirement (i.e, are "hard"), but lie farther from the anchor than the positive (not too hard). Restated, for each A ( i ) {\displaystyle A^{(i)}} and P ( i ) {\displaystyle P^{(i)}} , they seek N ( i ) {\displaystyle N^{(i)}} such that: The rationale for this design choice is heuristic. It may appear puzzling that the mining process neglects "very hard" negatives (i.e., closer to the anchor than the positive). Experiments conducted by the FaceNet designers found that this often leads to a convergence to degenerate local minima. Triplet mining is performed at each training step, from within the sample points contained in the training batch (this is known as online mining), after embeddings were computed for all points in the batch. While ideally the entire dataset could be used, this is impractical in general. To support a large search space for triplets, the FaceNet authors used very large batches (1800 samples). Batches are constructed by selecting a large number of same-category sample points (40), and randomly selected negatives for them. == Extensions == Triplet loss has been extended to simultaneously maintain a series of distance orders by optimizing a continuous relevance degree with a chain (i.e., ladder) of distance inequalities. This leads to the Ladder Loss, which has been demonstrated to offer performance enhancements of visual-semantic embedding in learning to rank tasks. In Natural Language Processing, triplet loss is one of the loss functions considered for BERT fine-tuning in the SBERT architecture. Other extensions involve specifying multiple negatives (multiple negatives ranking loss).

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  Ho–Kashyap algorithm

  The Ho–Kashyap algorithm is an iterative method in machine learning for finding a linear decision boundary that separates two linearly separable classes. It was developed by Yu-Chi Ho and Rangasami L. Kashyap in 1965, and usually presented as a problem in linear programming. == Setup == Given a training set consisting of samples from two classes, the Ho–Kashyap algorithm seeks to find a weight vector w {\displaystyle \mathbf {w} } and a margin vector b {\displaystyle \mathbf {b} } such that: Y w = b {\displaystyle \mathbf {Yw} =\mathbf {b} } where Y {\displaystyle \mathbf {Y} } is the augmented data matrix with samples from both classes (with appropriate sign conventions, e.g., samples from class 2 are negated), w {\displaystyle \mathbf {w} } is the weight vector to be determined, and b {\displaystyle \mathbf {b} } is a positive margin vector. The algorithm minimizes the criterion function: J ( w , b ) = | | Y w − b | | 2 {\displaystyle J(\mathbf {w} ,\mathbf {b} )=||\mathbf {Yw} -\mathbf {b} ||^{2}} subject to the constraint that b > 0 {\displaystyle \mathbf {b} >\mathbf {0} } (element-wise). Given a problem of linearly separating two classes, we consider a dataset of elements { ( x i , y i ) } i ∈ 1 : N {\displaystyle \{(\mathbf {x_{i}} ,y_{i})\}_{i\in 1:N}} where y i ∈ { − 1 , + 1 } {\displaystyle y_{i}\in \{-1,+1\}} . Linearly separating them by a perceptron is equivalent to finding weight and bias w , b {\displaystyle \mathbf {w} ,b} for a perceptron, such that: [ y 1 x 1 1 ⋮ ⋮ y N x N 1 ] [ w b ] > 0 {\displaystyle {\begin{bmatrix}y_{1}\mathbf {x} _{1}&1\\\vdots &\vdots \\y_{N}\mathbf {x} _{N}&1\\\end{bmatrix}}{\begin{bmatrix}\mathbf {w} \\b\end{bmatrix}}>0} == Algorithm == The idea of the Ho–Kashyap algorithm is as follows: Given any b {\displaystyle \mathbf {b} } , the corresponding w {\displaystyle \mathbf {w} } is known: It is simply w = Y + b {\displaystyle \mathbf {w} =\mathbf {Y} ^{+}\mathbf {b} } , where Y + {\displaystyle \mathbf {Y} ^{+}} denotes the Moore–Penrose pseudoinverse of Y {\displaystyle \mathbf {Y} } . Therefore, it only remains to find b {\displaystyle \mathbf {b} } by gradient descent. However, the gradient descent may sometimes decrease some of the coordinates of b {\displaystyle \mathbf {b} } , which may cause some coordinates of b {\displaystyle \mathbf {b} } to become negative, which is undesirable. Therefore, whenever some coordinates of b {\displaystyle \mathbf {b} } would have decreased, those coordinates are unchanged instead. As for the coordinates of b {\displaystyle \mathbf {b} } that would increase, those would increase without issue. Formally, the algorithm is as follows: Initialization: Set b ( 0 ) {\displaystyle \mathbf {b} (0)} to an arbitrary positive vector, typically b ( 0 ) = 1 {\displaystyle \mathbf {b} (0)=\mathbf {1} } (a vector of ones). Set the iteration counter k = 0 {\displaystyle k=0} . Set w ( 0 ) = Y + b ( 0 ) {\displaystyle \mathbf {w} (0)=\mathbf {Y} ^{+}\mathbf {b} (0)} Loop until convergence, or until iteration counter exceeds some k m a x {\displaystyle k_{max}} . Error calculation: Compute the error vector: e ( k ) = Y w ( k ) − b ( k ) {\displaystyle \mathbf {e} (k)=\mathbf {Yw} (k)-\mathbf {b} (k)} . Margin update: Update the margin vector: b ( k + 1 ) = b ( k ) + 2 η k ( e ( k ) + | e ( k ) | ) {\displaystyle \mathbf {b} (k+1)=\mathbf {b} (k)+2\eta _{k}(\mathbf {e} (k)+|\mathbf {e} (k)|)} where η k {\displaystyle \eta _{k}} is a positive learning rate parameter, and | e ( k ) | {\displaystyle |\mathbf {e} (k)|} denotes the element-wise absolute value. Weight calculation: Compute the weight vector using the pseudoinverse: w ( k + 1 ) = Y + b ( k + 1 ) {\displaystyle \mathbf {w} (k+1)=\mathbf {Y} ^{+}\mathbf {b} (k+1)} . Convergence check: If | | e ( k ) | | ≤ θ {\displaystyle ||\mathbf {e} (k)||\leq \theta } for some predetermined threshold θ {\displaystyle \theta } (close to zero), then return b ( k + 1 ) , w ( k + 1 ) {\displaystyle \mathbf {b} (k+1),\mathbf {w} (k+1)} . if e ( k ) ≤ 0 {\displaystyle \mathbf {e} (k)\leq \mathbf {0} } (all components non-positive), return "Samples not separable.". Return "Algorithm failed to converge in time.". == Properties == If the training data is linearly separable, the algorithm converges to a solution (where e ( k ) = 0 {\displaystyle \mathbf {e} (k)=\mathbf {0} } ) in a finite number of iterations. If the data is not linearly separable, the algorithm may or may not ever reach the point where e ( k ) = 0 {\displaystyle \mathbf {e} (k)=\mathbf {0} } . However, if it does happen that e ( k ) ≤ 0 {\displaystyle \mathbf {e} (k)\leq \mathbf {0} } at some iteration, this proves non-separability. The convergence rate depends on the choice of the learning rate parameter ρ {\displaystyle \rho } and the degree of linear separability of the data. == Relationship to other algorithms == Perceptron algorithm: Both seek linear separators. The perceptron updates weights incrementally based on individual misclassified samples, while Ho–Kashyap is a batch method that processes all samples to compute the pseudoinverse and updates based on an overall error vector. Linear discriminant analysis (LDA): LDA assumes underlying Gaussian distributions with equal covariances for the classes and derives the decision boundary from these statistical assumptions. Ho–Kashyap makes no explicit distributional assumptions and instead tries to solve a system of linear inequalities directly. Support vector machines (SVM): For linearly separable data, SVMs aim to find the maximum-margin hyperplane. The Ho–Kashyap algorithm finds a separating hyperplane but not necessarily the one with the maximum margin. If the data is not separable, soft-margin SVMs allow for some misclassifications by optimizing a trade-off between margin size and misclassification penalty, while Ho–Kashyap provides a least-squares solution. == Variants == Modified Ho–Kashyap algorithm changes weight calculation step w ( k + 1 ) = Y + b ( k + 1 ) {\displaystyle \mathbf {w} (k+1)=\mathbf {Y} ^{+}\mathbf {b} (k+1)} to w ( k + 1 ) = w ( k ) + η k Y + | e ( k ) | {\displaystyle \mathbf {w} (k+1)=\mathbf {w} (k)+\eta _{k}\mathbf {Y} ^{+}|\mathbf {e} (k)|} . Kernel Ho–Kashyap algorithm: Applies kernel methods (the "kernel trick") to the Ho–Kashyap framework to enable non-linear classification by implicitly mapping data to a higher-dimensional feature space.

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  Lattice Miner

  Lattice Miner is a formal concept analysis software tool for the construction, visualization and manipulation of concept lattices. It allows the generation of formal concepts and association rules as well as the transformation of formal contexts via apposition, subposition, reduction and object/attribute generalization, and the manipulation of concept lattices via approximation, projection and selection. Lattice Miner allows also the drawing of nested line diagrams. == Introduction == Formal concept analysis (FCA) is a branch of applied mathematics based on the formalization of concept and concept hierarchy and mainly used as a framework for conceptual clustering and rule mining. Over the last two decades, a collection of tools have emerged to help FCA users visualize and analyze concept lattices. They range from the earliest DOS-based implementations (e.g., ConImp and GLAD) to more recent implementations in Java like ToscanaJ, Galicia, ConExp and Coron. A main issue in the development of FCA tools is to visualize large concept lattices and provide efficient mechanisms to highlight patterns (e.g., concepts, associations) that could be relevant to the user. The initial objective of the FCA tool called Lattice Miner was to focus on visualization mechanisms for the representation of concept lattices, including nested line diagrams. Later on, many other interesting features were integrated into the tool. == Functional architecture of Lattice Miner == Lattice Miner is a Java-based platform whose functions are articulated around a core. The Lattice Miner core provides all low-level operations and structures for the representation and manipulation of contexts, lattices and association rules. Mainly, the core of Lattice Miner consists of three modules: context, concept and association rule modules. The user interface offers a context editor and concept lattice manipulator to assist the user in a set of tasks. The architecture of Lattice Miner is open and modular enough to allow the integration of new features and facilities in each one of its components. === Context module === The context module offers all the basic operations and structures to manipulate binary and valued contexts as well as context decomposition to produce nested line diagrams. Basic context operations include apposition, subposition, generalization, clarification, reduction as well as the complementary context computation. The module provides also the arrow relations (for context reduction and decomposition) [2]. The tool has an input LMB format and recognizes the binary format SLF found in Galicia and the format CEX produced by ConExp. === Concept module === The main function of the concept module is to generate the concepts of the current binary context and construct the corresponding lattice and nested structure (see Figures 2 and 3). It provides the user with basic operators such as projection, selection, and exact search as well as advanced features like pair approximation. Some known algorithms are included in this module such as Bordat’s procedure, Godin’s algorithm and NextClosure algorithm. The approximation feature implemented in Lattice Miner is based on the following idea: given a pair (X,Y) where X ⊆ G, and Y ⊆ M, is there a set of formal concepts (Ai,Bi) which are “close to” (X,Y)? To answer this question, The tool starts to identify the type of couple that the pair (X,Y) represents. It can be a formal concept, a protoconcept, a semiconcept or a preconcept. In the last case, the approximation is given by the interval [(X",X′),(Y′,Y")] and highlighted in the line diagram. === Association rule module === This module includes procedures for computing the (stem) Guigues–Duquenne base using NextClosure algorithm [3], as well as the generic and informative bases. Implications with negation can be obtained using the apposition of a context and its complementary. This module embeds also procedures for the computation of a non-redundant family C of implications and the closure of a set Y of attributes for the given implication set C. === User interface === The initial objective of Lattice Miner was to focus on lattice drawing and visualization either as a flat or nested structure by taking into account the cognitive process of human beings and known principles for lattice drawing (e.g., reducing the number of edge intersections, ensuring diagram symmetry). Some well-known visualization techniques were implemented such as focus & context and fisheye view. The basic idea behind focus & context visualization paradigm is to allow a viewer to see key (important) objects in full detail in the foreground (focus) while at the same time an overview of all the surrounding information (context) remains available in the background. Lattice Miner translates the focus & context paradigm into clear and blurred elements while the size of nodes and the intensity of their color were used to indicate their importance. Various forms of highlighting, labelling and animation are also provided. In order to better handle the display of large lattices, nested line diagrams are offered in the tool. Figure 3 shows the third level of the nested line diagram corresponding to the binary context of Figure 1 where three levels of nesting are defined. Each one of the inner nodes of this diagram represents a combination of attributes from the previous two (outer) levels. Real inner concepts (see the node on the left hand-side of the diagram) are identified by colored nodes while void elements are in grey color. Each node of levels 1 and 2 can be expanded to exhibit its internal line diagram. Both flat and nested diagrams can be saved as an image. Simple (flat) lattices can also be saved as an XML format file.

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  Automatic summarization

  Automatic summarization is the process of shortening a set of data computationally, to create a subset (a summary) that represents the most important or relevant information within the original content. Artificial intelligence (AI) algorithms are commonly developed and employed to achieve this, specialized for different types of data. Text summarization is usually implemented by natural language processing methods, designed to locate the most informative sentences in a given document. On the other hand, visual content can be summarized using computer vision algorithms. Image summarization is the subject of ongoing research; existing approaches typically attempt to display the most representative images from a given image collection, or generate a video that only includes the most important content from the entire collection. Video summarization algorithms identify and extract from the original video content the most important frames (key-frames), and/or the most important video segments (key-shots), normally in a temporally ordered fashion. Video summaries simply retain a carefully selected subset of the original video frames and, therefore, are not identical to the output of video synopsis algorithms, where new video frames are being synthesized based on the original video content. == Commercial products == In 2022 Google Docs released an automatic summarization feature. == Approaches == There are two general approaches to automatic summarization: extraction and abstraction. === Extraction-based summarization === Here, content is extracted from the original data, but the extracted content is not modified in any way. Examples of extracted content include key-phrases that can be used to "tag" or index a text document, or key sentences (including headings) that collectively comprise an abstract, and representative images or video segments, as stated above. For text, extraction is analogous to the process of skimming, where the summary (if available), headings and subheadings, figures, the first and last paragraphs of a section, and optionally the first and last sentences in a paragraph are read before one chooses to read the entire document in detail. Other examples of extraction that include key sequences of text in terms of clinical relevance (including patient/problem, intervention, and outcome). === Abstractive-based summarization === Abstractive summarization methods generate new text that did not exist in the original text. This has been applied mainly for text. Abstractive methods build an internal semantic representation of the original content (often called a language model), and then use this representation to create a summary that is closer to what a human might express. Abstraction may transform the extracted content by paraphrasing sections of the source document, to condense a text more strongly than extraction. Such transformation, however, is computationally much more challenging than extraction, involving both natural language processing and often a deep understanding of the domain of the original text in cases where the original document relates to a special field of knowledge. "Paraphrasing" is even more difficult to apply to images and videos, which is why most summarization systems are extractive. === Aided summarization === Approaches aimed at higher summarization quality rely on combined software and human effort. In Machine Aided Human Summarization, extractive techniques highlight candidate passages for inclusion (to which the human adds or removes text). In Human Aided Machine Summarization, a human post-processes software output, in the same way that one edits the output of automatic translation by Google Translate. == Applications and systems for summarization == There are broadly two types of extractive summarization tasks depending on what the summarization program focuses on. The first is generic summarization, which focuses on obtaining a generic summary or abstract of the collection (whether documents, or sets of images, or videos, news stories etc.). The second is query relevant summarization, sometimes called query-based summarization, which summarizes objects specific to a query. Summarization systems are able to create both query relevant text summaries and generic machine-generated summaries depending on what the user needs. An example of a summarization problem is document summarization, which attempts to automatically produce an abstract from a given document. Sometimes one might be interested in generating a summary from a single source document, while others can use multiple source documents (for example, a cluster of articles on the same topic). This problem is called multi-document summarization. A related application is summarizing news articles. Imagine a system, which automatically pulls together news articles on a given topic (from the web), and concisely represents the latest news as a summary. Image collection summarization is another application example of automatic summarization. It consists in selecting a representative set of images from a larger set of images. A summary in this context is useful to show the most representative images of results in an image collection exploration system. Video summarization is a related domain, where the system automatically creates a trailer of a long video. This also has applications in consumer or personal videos, where one might want to skip the boring or repetitive actions. Similarly, in surveillance videos, one would want to extract important and suspicious activity, while ignoring all the boring and redundant frames captured. At a very high level, summarization algorithms try to find subsets of objects (like set of sentences, or a set of images), which cover information of the entire set. This is also called the core-set. These algorithms model notions like diversity, coverage, information and representativeness of the summary. Query based summarization techniques, additionally model for relevance of the summary with the query. Some techniques and algorithms which naturally model summarization problems are TextRank and PageRank, Submodular set function, Determinantal point process, maximal marginal relevance (MMR) etc. === Keyphrase extraction === The task is the following. You are given a piece of text, such as a journal article, and you must produce a list of keywords or key[phrase]s that capture the primary topics discussed in the text. In the case of research articles, many authors provide manually assigned keywords, but most text lacks pre-existing keyphrases. For example, news articles rarely have keyphrases attached, but it would be useful to be able to automatically do so for a number of applications discussed below. Consider the example text from a news article: "The Army Corps of Engineers, rushing to meet President Bush's promise to protect New Orleans by the start of the 2006 hurricane season, installed defective flood-control pumps last year despite warnings from its own expert that the equipment would fail during a storm, according to documents obtained by The Associated Press". A keyphrase extractor might select "Army Corps of Engineers", "President Bush", "New Orleans", and "defective flood-control pumps" as keyphrases. These are pulled directly from the text. In contrast, an abstractive keyphrase system would somehow internalize the content and generate keyphrases that do not appear in the text, but more closely resemble what a human might produce, such as "political negligence" or "inadequate protection from floods". Abstraction requires a deep understanding of the text, which makes it difficult for a computer system. Keyphrases have many applications. They can enable document browsing by providing a short summary, improve information retrieval (if documents have keyphrases assigned, a user could search by keyphrase to produce more reliable hits than a full-text search), and be employed in generating index entries for a large text corpus. Depending on the different literature and the definition of key terms, words or phrases, keyword extraction is a highly related theme. ==== Supervised learning approaches ==== Beginning with the work of Turney, many researchers have approached keyphrase extraction as a supervised machine learning problem. Given a document, we construct an example for each unigram, bigram, and trigram found in the text (though other text units are also possible, as discussed below). We then compute various features describing each example (e.g., does the phrase begin with an upper-case letter?). We assume there are known keyphrases available for a set of training documents. Using the known keyphrases, we can assign positive or negative labels to the examples. Then we learn a classifier that can discriminate between positive and negative examples as a function of the features. Some classifiers make a binary classification for a test example, while others assign a probability of being a keyphrase. For ins

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  Julia (programming language)

  Julia is a dynamic general-purpose programming language. As a high-level language, distinctive aspects of Julia's design include a type system with parametric polymorphism, the use of multiple dispatch as a core programming paradigm, just-in-time compilation and a parallel garbage collection implementation. Notably, Julia does not support classes with encapsulated methods but instead relies on the types of all of a function's arguments to determine which method will be called. By default, Julia is run similarly to scripting languages, using its runtime, and allows for interactions, but Julia programs can also be compiled to small binary standalone executables (or to small libraries for e.g. Python), with e.g. the JuliaC.jl compiler. Julia programs can reuse libraries from other languages, and vice versa. Julia has interoperability with C, C++, Fortran, Rust, Python, and R. Additionally, some Julia packages have bindings to be used from Python and R as libraries. Julia is supported by programmer tools like IDEs (see below) and by notebooks like Pluto.jl, Jupyter, and since 2025, Google Colab officially supports Julia natively. Julia is sometimes used in embedded systems (e.g. has been used in a satellite in space on a Raspberry Pi Compute Module 4; 64-bit Pis work best with Julia, and Julia is supported in Raspbian). == History == Work on Julia began in 2009, when Jeff Bezanson, Stefan Karpinski, Viral B. Shah, and Alan Edelman set out to create a free language that was both high-level and fast. On 14 February 2012, the team launched a website with a blog post explaining the language's mission. In an interview with InfoWorld in April 2012, Karpinski said about the name of the language, Julia: "There's no good reason, really. It just seemed like a pretty name." Bezanson said he chose the name on the recommendation of a friend, then years later wrote: Maybe julia stands for "Jeff's uncommon lisp is automated"? Julia's syntax is stable, since version 1.0 in 2018, and Julia has a backward compatibility guarantee for 1.x and also a stability promise for the documented (stable) API, while in the years before in the early development prior to 0.7 the syntax (and semantics) was changed in new versions. All of the (registered package) ecosystem uses the new and improved syntax, and in most cases relies on new APIs that have been added regularly, and in some cases minor additional syntax added in a forward compatible way e.g. in Julia 1.7. In the 10 years since the 2012 launch of pre-1.0 Julia, the community has grown. The Julia package ecosystem has over 11.8 million lines of code (including docs and tests). The JuliaCon academic conference for Julia users and developers has been held annually since 2014 with JuliaCon2020 welcoming over 28,900 unique viewers, and then JuliaCon2021 breaking all previous records (with more than 300 JuliaCon2021 presentations available for free on YouTube, up from 162 the year before), and 43,000 unique viewers during the conference. Three of the Julia co-creators are the recipients of the 2019 James H. Wilkinson Prize for Numerical Software (awarded every four years) "for the creation of Julia, an innovative environment for the creation of high-performance tools that enable the analysis and solution of computational science problems." Also, Alan Edelman, professor of applied mathematics at MIT, has been selected to receive the 2019 IEEE Computer Society Sidney Fernbach Award "for outstanding breakthroughs in high-performance computing, linear algebra, and computational science and for contributions to the Julia programming language." Version 0.3 was released in August 2014. Both Julia 0.7 and version 1.0 were released on 8 August 2018. Julia 1.4 added syntax for generic array indexing to handle e.g. 0-based arrays. The memory model was also changed. Julia 1.5 released in August 2020 added record and replay debugging support, for Mozilla's rr tool. The release changed the behavior in the REPL (to soft scope) to the one used in Jupyter, but keeps full compatible with non-REPL code (that retains hard scope). Julia 1.6 was the largest release since 1.0, and it was the long-term support (LTS) version for the longest time. Since Julia 1.7 development is back to time-based releases, and it was released in November 2021 with e.g. a new default random-number generator and Julia 1.7.3 fixed at least one security issue. Julia 1.8 added options for hiding source code when compiling Julia source code to executables. Julia 1.9 has added the ability to precompile packages to native machine code, done automatically; to improve precompilation of packages a new package PrecompileTools.jl was introduced, for use by package developers. Julia 1.10 was released on 25 December 2023 with new features such as parallel garbage collection. Julia 1.11 was released on 7 October 2024, and with it 1.10.5 became the next long-term support (LTS) version (i.e. those became the only two supported versions), since replaced by 1.10.10 released on 27 June, and 1.6 is no longer an LTS version. Julia 1.11 adds e.g. the new public keyword to signal safe public API (Julia users are advised to use such API, not internals, of Julia or packages, and package authors advised to use the keyword, generally indirectly, e.g. prefixed with the @compat macro, from Compat.jl, to also support older Julia versions, at least the LTS version). Julia 1.12 was released on 7 October 2025 (and 1.12.5 on 9 February 2026), and with it a JuliaC.jl package including the juliac compiler that works with it, for making rather small binary executables (much smaller than was possible before; through the use of new so-called trimming feature). Julia 1.10 LTS is an officially still-supported branch, but the 1.11 branch has also been maintained after 1.12 release, with 1.11.8 released and then 1.11.9 released on 8 February 2026. === JuliaCon === Since 2014, the Julia Community has hosted an annual Julia Conference focused on developers and users. The first JuliaCon took place in Chicago and kickstarted the annual occurrence of the conference. Since 2014, the conference has taken place across a number of locations including MIT and the University of Maryland, Baltimore. The event audience has grown from a few dozen people to over 28,900 unique attendees during JuliaCon 2020, which took place virtually. JuliaCon 2021 also took place virtually with keynote addresses from professors William Kahan, the primary architect of the IEEE 754 floating-point standard (which virtually all CPUs and languages, including Julia, use), Jan Vitek, Xiaoye Sherry Li, and Soumith Chintala, a co-creator of PyTorch. JuliaCon grew to 43,000 unique attendees and more than 300 presentations (still freely accessible, plus for older years). JuliaCon 2022 will also be virtual held between July 27 and July 29, 2022, for the first time in several languages, not just in English. === Sponsors === The Julia language became a NumFOCUS fiscally sponsored project in 2014 in an effort to ensure the project's long-term sustainability. Jeremy Kepner at MIT Lincoln Laboratory was the founding sponsor of the Julia project in its early days. In addition, funds from the Gordon and Betty Moore Foundation, the Alfred P. Sloan Foundation, Intel, and agencies such as NSF, DARPA, NIH, NASA, and FAA have been essential to the development of Julia. Mozilla, the maker of Firefox web browser, with its research grants for H1 2019, sponsored "a member of the official Julia team" for the project "Bringing Julia to the Browser", meaning to Firefox and other web browsers. The Julia language is also supported by individual donors on GitHub. === The Julia company === JuliaHub, Inc. was founded in 2015 as Julia Computing, Inc. by Viral B. Shah, Deepak Vinchhi, Alan Edelman, Jeff Bezanson, Stefan Karpinski and Keno Fischer. In June 2017, Julia Computing raised US$4.6 million in seed funding from General Catalyst and Founder Collective, the same month was "granted $910,000 by the Alfred P. Sloan Foundation to support open-source Julia development, including $160,000 to promote diversity in the Julia community", and in December 2019 the company got $1.1 million funding from the US government to "develop a neural component machine learning tool to reduce the total energy consumption of heating, ventilation, and air conditioning (HVAC) systems in buildings". In July 2021, Julia Computing announced they raised a $24 million Series A round led by Dorilton Ventures, which also owns Formula One team Williams Racing, that partnered with Julia Computing. Williams' Commercial Director said: "Investing in companies building best-in-class cloud technology is a strategic focus for Dorilton and Julia's versatile platform, with revolutionary capabilities in simulation and modelling, is hugely relevant to our business. We look forward to embedding Julia Computing in the world's most technologically advanced sport". In June 2023, JuliaHub received (again, now

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  Targeted maximum likelihood estimation

  Targeted Maximum Likelihood Estimation (TMLE) (also more accurately referred to as Targeted Minimum Loss-Based Estimation) is a general statistical estimation framework for causal inference and semiparametric models. TMLE combines ideas from maximum likelihood estimation, semiparametric efficiency theory, and machine learning. It was introduced by Mark J. van der Laan and colleagues in the mid-2000s as a method that yields asymptotically efficient plug-in estimators while allowing the use of flexible, data-adaptive algorithms such as ensemble machine learning for nuisance parameter estimation. TMLE is used in epidemiology, biostatistics, and the social sciences to estimate causal effects in observational and experimental studies. Applications of TMLE include Longitudinal TMLE (LTMLE) for time-varying treatments and confounders. Variations in how the targeting step in TMLE is carried out have resulted in various versions of TMLE such as Collaborative TMLE (CTMLE) and Adaptive TMLE for improved finite-sample performance and automated variable selection. == History == The TMLE framework was first described by van der Laan and Rubin (2006) as a general approach for the construction of efficient plug-in estimators of smooth features of the data density. It was demonstrated in the context of causal inference and missing data problems. It was developed to address limitations of traditional doubly robust methods, such as Augmented Inverse Probability Weighting (AIPW), by respecting the plug-in principle in the sense that it respects that the target parameter is a function of the data density that is an element of the statistical model. TMLE estimates the data density or relevant parts of it with machine learning and targets these machine learning fits before it is plugged in the target parameter mapping. In this manner, a TMLE always respects global knowledge and satisfies known bounds such as that the target parameter is a probability . Since its introduction, TMLE has been developed in a series of theoretical and applied papers, culminating in book-length treatments of the method and its applications to survival analysis, adaptive designs, and longitudinal data. == Methodology == At its core, TMLE is a two-step estimation procedure: Initial estimation: Machine learning methods (such as the Super Learner ensemble) are used to obtain flexible estimates of nuisance parameters, such as outcome regressions and propensity scores. Targeting step: The initial estimate is updated by solving a score equation (the efficient influence function) so that the final estimator is consistent, asymptotically normal, and efficient under mild regularity conditions. The targeted machine learning fit is then mapped into the corresponding estimator of the target parameter by simply plugging it in the target parameter mapping. This approach balances the bias–variance trade-off by combining data-adaptive estimation with semiparametric efficiency theory. TMLE is doubly robust, meaning it remains consistent if either the outcome model or the treatment model is consistently estimated. === Formula === Here we explain the TMLE of the average treatment effect of a binary treatment on an outcome adjusting for baseline covariates. Consider i.i.d. observations O i = ( W i , A i , Y i ) {\displaystyle O_{i}=(W_{i},A_{i},Y_{i})} from a distribution P 0 {\displaystyle P_{0}} , where W {\displaystyle W} are baseline covariates, A {\displaystyle A} is a binary treatment, and Y {\displaystyle Y} is an outcome. Let Q ¯ ( a , w ) = E [ Y ∣ A = a , W = w ] {\displaystyle {\bar {Q}}(a,w)=\mathbb {E} [Y\mid A=a,W=w]} represent the outcome model and g ( a ∣ w ) = P ( A = a ∣ W = w ) {\displaystyle g(a\mid w)=P(A=a\mid W=w)} represent the propensity score. The average treatment effect (ATE) is given by ψ 0 = E { Q ¯ ( 1 , W ) − Q ¯ ( 0 , W ) } . {\displaystyle \psi _{0}=\mathbb {E} \{{\bar {Q}}(1,W)-{\bar {Q}}(0,W)\}.} A basic TMLE for the ATE proceeds as follows: Step 1: Estimate initial models. Obtain estimates Q ¯ ^ ( a , w ) {\displaystyle {\hat {\bar {Q}}}(a,w)} and g ^ ( a ∣ w ) {\displaystyle {\hat {g}}(a\mid w)} , often using flexible methods such as Super Learner. Step 2: Compute the clever covariate. Define: H ( A , W ) = A g ^ ( 1 ∣ W ) − 1 − A g ^ ( 0 ∣ W ) . {\displaystyle H(A,W)={\frac {A}{{\hat {g}}(1\mid W)}}-{\frac {1-A}{{\hat {g}}(0\mid W)}}.} Step 3: Estimate the fluctuation parameter. Fit a logistic regression of Y {\displaystyle Y} on H ( A , W ) {\displaystyle H(A,W)} with logit ⁡ ( Q ¯ ^ ( A , W ) ) {\displaystyle \operatorname {logit} ({\hat {\bar {Q}}}(A,W))} as offset. This yields ε ^ {\displaystyle {\hat {\varepsilon }}} , the MLE that solves the score equation: 1 n ∑ i = 1 n H ( A i , W i ) { Y i − Q ¯ ^ ε ( A i , W i ) } = 0. {\displaystyle {\frac {1}{n}}\sum _{i=1}^{n}H(A_{i},W_{i}){\big \{}Y_{i}-{\hat {\bar {Q}}}^{\varepsilon }(A_{i},W_{i}){\big \}}=0.} Step 4: Update the initial estimate. Apply the "blip" to obtain the targeted estimate: Q ¯ ^ ∗ ( A , W ) = expit ⁡ ( logit ⁡ ( Q ¯ ^ ( A , W ) ) + ε ^ H ( A , W ) ) . {\displaystyle {\hat {\bar {Q}}}^{}(A,W)=\operatorname {expit} {\Big (}\operatorname {logit} {\big (}{\hat {\bar {Q}}}(A,W){\big )}+{\hat {\varepsilon }}\,H(A,W){\Big )}.} Step 5: Compute the TMLE. The ATE estimate is: ψ ^ TMLE = 1 n ∑ i = 1 n [ Q ¯ ^ ∗ ( 1 , W i ) − Q ¯ ^ ∗ ( 0 , W i ) ] . {\displaystyle {\hat {\psi }}_{\text{TMLE}}={\frac {1}{n}}\sum _{i=1}^{n}{\big [}{\hat {\bar {Q}}}^{}(1,W_{i})-{\hat {\bar {Q}}}^{}(0,W_{i}){\big ]}.} Inference. The efficient influence function (EIF) for the ATE is: D ∗ ( O ) = H ( A , W ) { Y − Q ¯ ∗ ( A , W ) } + Q ¯ ∗ ( 1 , W ) − Q ¯ ∗ ( 0 , W ) − ψ . {\displaystyle D^{}(O)=H(A,W)\{Y-{\bar {Q}}^{}(A,W)\}+{\bar {Q}}^{}(1,W)-{\bar {Q}}^{}(0,W)-\psi .} The variance is estimated by σ ^ 2 = n − 1 ∑ i = 1 n ( D ∗ ( O i ) ) 2 {\displaystyle {\hat {\sigma }}^{2}=n^{-1}\sum _{i=1}^{n}{\big (}D^{}(O_{i}){\big )}^{2}} , yielding Wald-type confidence intervals ψ ^ TMLE ± z 1 − α / 2 σ ^ / n {\displaystyle {\hat {\psi }}_{\text{TMLE}}\pm z_{1-\alpha /2}\,{\hat {\sigma }}/{\sqrt {n}}} . Remark. For continuous outcomes, a linear fluctuation Q ¯ ^ ∗ = Q ¯ ^ + ε ^ H {\displaystyle {\hat {\bar {Q}}}^{}={\hat {\bar {Q}}}+{\hat {\varepsilon }}\,H} may be used instead. For bounded continuous outcomes, the logistic fluctuation (after rescaling Y {\displaystyle Y} to [ 0 , 1 ] {\displaystyle [0,1]} ) is often preferred for improved finite-sample performance. == Applications == TMLE has been applied in: Epidemiology: Estimating causal effects of exposures and interventions in observational cohort studies. Clinical trials and real-world evidence: The Targeted Learning roadmap provides a structured framework for generating and validating real-world evidence (RWE), bridging randomized trials and observational data using TMLE and related estimation techniques. This approach enables transparency, sensitivity analysis, and stronger causal inference for regulatory and clinical trial contexts. High-dimensional settings: Integration with ensemble methods for causal effect estimation. TMLE has been successfully applied in pharmacoepidemiology where a large number of covariates are automatically selected to adjust for confounding. In a study of post–myocardial infarction statin use and 1-year mortality, TMLE demonstrated robust performance relative to inverse probability weighting in scenarios with hundreds of potential confounders. == Derivatives and extensions == Longitudinal TMLE (LTMLE): A methodological extension of TMLE for longitudinal data with time-varying treatments, confounders, and censoring. It allows the estimation of dynamic treatment regimes and intervention-specific causal effects over time. This framework was originally introduced by van der Laan & Gruber (2012). Collaborative TMLE (CTMLE): Enhances finite-sample performance and variable selection by collaboratively fitting the treatment mechanism in conjunction with the target parameter. == Software == Several R packages implement TMLE and related methods: tmle: Functions for binary, categorical, and continuous outcomes. ltmle: Implementation for longitudinal data with time-varying treatments and outcomes. ctmle: Algorithms for collaborative TMLE and adaptive variable selection. SuperLearner: A theoretically grounded, cross-validated ensemble learning method that combines predictions from multiple algorithms to minimize predictive risk. Widely used in TMLE for estimating nuisance parameters. The original implementation is available as the R package SuperLearner. Recent machine learning platforms like H2O AutoML implement similar ensemble strategies, combining diverse learners in parallel and leveraging stacking and blending techniques, effectively functioning as a large-scale Super Learner.

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