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Developmental robotics

Developmental robotics (DevRob), sometimes called epigenetic robotics, is a scientific field which aims at studying the developmental mechanisms, architectures and constraints that allow lifelong and open-ended learning of new skills and new knowledge in embodied machines. As in human children, learning is expected to be cumulative and of progressively increasing complexity, and to result from self-exploration of the world in combination with social interaction. The typical methodological approach consists in starting from theories of human and animal development elaborated in fields such as developmental psychology, neuroscience, developmental and evolutionary biology, and linguistics, then to formalize and implement them in robots, sometimes exploring extensions or variants of them. The experimentation of those models in robots allows researchers to confront them with reality, and as a consequence, developmental robotics also provides feedback and novel hypotheses on theories of human and animal development. Developmental robotics is related to but differs from evolutionary robotics (ER). ER uses populations of robots that evolve over time, whereas DevRob is interested in how the organization of a single robot's control system develops through experience, over time. DevRob is also related to work done in the domains of robotics and artificial life. == Background == Can a robot learn like a child? Can it learn a variety of new skills and new knowledge unspecified at design time and in a partially unknown and changing environment? How can it discover its body and its relationships with the physical and social environment? How can its cognitive capacities continuously develop without the intervention of an engineer once it is "out of the factory"? What can it learn through natural social interactions with humans? These are the questions at the center of developmental robotics. Alan Turing, as well as a number of other pioneers of cybernetics, already formulated those questions and the general approach in 1950, but it is only since the end of the 20th century that they began to be investigated systematically. Because the concept of adaptive intelligent machines is central to developmental robotics, it has relationships with fields such as artificial intelligence, machine learning, cognitive robotics or computational neuroscience. Yet, while it may reuse some of the techniques elaborated in these fields, it differs from them from many perspectives. It differs from classical artificial intelligence because it does not assume the capability of advanced symbolic reasoning and focuses on embodied and situated sensorimotor and social skills rather than on abstract symbolic problems. It differs from cognitive robotics because it focuses on the processes that allow the formation of cognitive capabilities rather than these capabilities themselves. It differs from computational neuroscience because it focuses on functional modeling of integrated architectures of development and learning. More generally, developmental robotics is uniquely characterized by the following three features: It targets task-independent architectures and learning mechanisms, i.e. the machine/robot has to be able to learn new tasks that are unknown by the engineer; It emphasizes open-ended development and lifelong learning, i.e. the capacity of an organism to acquire continuously novel skills. This should not be understood as a capacity for learning "anything" or even “everything”, but just that the set of skills that is acquired can be infinitely extended at least in some (not all) directions; The complexity of acquired knowledge and skills shall increase (and the increase be controlled) progressively. Developmental robotics emerged at the crossroads of several research communities including embodied artificial intelligence, enactive and dynamical systems cognitive science, connectionism. Starting from the essential idea that learning and development happen as the self-organized result of the dynamical interactions among brains, bodies and their physical and social environment, and trying to understand how this self-organization can be harnessed to provide task-independent lifelong learning of skills of increasing complexity, developmental robotics strongly interacts with fields such as developmental psychology, developmental and cognitive neuroscience, developmental biology (embryology), evolutionary biology, and cognitive linguistics. As many of the theories coming from these sciences are verbal and/or descriptive, this implies a crucial formalization and computational modeling activity in developmental robotics. These computational models are then not only used as ways to explore how to build more versatile and adaptive machines but also as a way to evaluate their coherence and possibly explore alternative explanations for understanding biological development. == Research directions == === Skill domains === Due to the general approach and methodology, developmental robotics projects typically focus on having robots develop the same types of skills as human infants. A first category that is important being investigated is the acquisition of sensorimotor skills. These include the discovery of one's own body, including its structure and dynamics such as hand-eye coordination, locomotion, and interaction with objects as well as tool use, with a particular focus on the discovery and learning of affordances. A second category of skills targeted by developmental robots are social and linguistic skills: the acquisition of simple social behavioural games such as turn-taking, coordinated interaction, lexicons, syntax and grammar, and the grounding of these linguistic skills into sensorimotor skills (sometimes referred as symbol grounding). In parallel, the acquisition of associated cognitive skills are being investigated such as the emergence of the self/non-self distinction, the development of attentional capabilities, of categorization systems and higher-level representations of affordances or social constructs, of the emergence of values, empathy, or theories of mind. === Mechanisms and constraints === The sensorimotor and social spaces in which humans and robot live are so large and complex that only a small part of potentially learnable skills can actually be explored and learnt within a life-time. Thus, mechanisms and constraints are necessary to guide developmental organisms in their development and control of the growth of complexity. There are several important families of these guiding mechanisms and constraints which are studied in developmental robotics, all inspired by human development: Motivational systems, generating internal reward signals that drive exploration and learning, which can be of two main types: extrinsic motivations push robots/organisms to maintain basic specific internal properties such as food and water level, physical integrity, or light (e.g. in phototropic systems); intrinsic motivations push robot to search for novelty, challenge, compression or learning progress per se, thus generating what is sometimes called curiosity-driven learning and exploration, or alternatively active learning and exploration; Social guidance: as humans learn a lot by interacting with their peers, developmental robotics investigates mechanisms that can allow robots to participate to human-like social interaction. By perceiving and interpreting social cues, this may allow robots both to learn from humans (through diverse means such as imitation, emulation, stimulus enhancement, demonstration, etc. ...) and to trigger natural human pedagogy. Thus, social acceptance of developmental robots is also investigated; Statistical inference biases and cumulative knowledge/skill reuse: biases characterizing both representations/encodings and inference mechanisms can typically allow considerable improvement of the efficiency of learning and are thus studied. Related to this, mechanisms allowing to infer new knowledge and acquire new skills by reusing previously learnt structures is also an essential field of study; The properties of embodiment, including geometry, materials, or innate motor primitives/synergies often encoded as dynamical systems, can considerably simplify the acquisition of sensorimotor or social skills, and is sometimes referred as morphological computation. The interaction of these constraints with other constraints is an important axis of investigation; Maturational constraints: In human infants, both the body and the neural system grow progressively, rather than being full-fledged already at birth. This implies, for example, that new degrees of freedom, as well as increases of the volume and resolution of available sensorimotor signals, may appear as learning and development unfold. Transposing these mechanisms in developmental robots, and understanding how it may hinder or on the contrary ease the acquisition of novel complex skills is a central questi
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Receptron

The receptron (short for "reservoir perceptron") is a neuromorphic data processing model — specifically neuromorphic computing — that generalizes the traditional perceptron, by incorporating non-linear interactions between inputs. Unlike classical perceptron, which rely on linearly independent weights, the receptron leverages complexity in physical substrates, such as the electric conduction properties of nanostructured materials or optical speckle fields, to perform classification tasks. The receptron bridges unconventional computing and neural network principles, enabling solutions that do not require the training approaches typical of artificial neural networks based on the perceptron model. == Algorithm == The receptron is an algorithm for supervised learning of binary classifiers, so a classification algorithm that makes its predictions based on a predictor function, combining a set of weights with the feature vector. The mathematical model is based on the sum of inputs with non-linear interactions: S = ∑ k = 1 n x j w ~ j ( x → ) | S ∈ R {\displaystyle S=\sum _{k=1}^{n}x_{j}{\widetilde {w}}_{j}({\vec {x}})|S\in R} (1) where j ∈ [ 1 , n ] {\displaystyle j\in [1,n]} and w ~ j {\displaystyle {\widetilde {w}}_{j}} are non-linear weight functions depending on the inputs, x → {\displaystyle {\vec {x}}} . Nonlinearity will typically make the system extremely complex, and allowing for the solution of problems not solvable through the simpler rules of a linear system, such as the perceptron or McCulloch Pitts neurons, which is based on the sum of linearly independent weights: S = ∑ k = 1 n x j w j p {\displaystyle S=\sum _{k=1}^{n}x_{j}w_{j}^{p}} (2) where w j {\displaystyle w_{j}} are constant real values. A consequence of this simplicity is the limitation to linearly separable functions, which necessitates multi-layer architectures and training algorithms like backpropagation As in the perceptron case, the summation in Eq. 1 origins the activation of the receptron output through the thresholding process, Y ( x 1 , . . . , x n ) = { 1 if S > th 0 if S ≤ th {\displaystyle Y(x_{1},...,x_{n})={\begin{cases}1&{\text{if }}S>{\text{th}}\\0&{\text{if }}S\leq {\text{th}}\end{cases}}} (3) where th is a constant threshold parameter. Equation 3 can be written by using the Heaviside step function. The weight functions w ~ ( x → ) {\displaystyle {\widetilde {w}}({\vec {x}})} can be written with a finite number of parameters w j 1 . . . j n {\displaystyle w_{j_{1}...j_{n}}} , simplifying the model representation. One can Taylor-expand w ~ ( x → ) {\displaystyle {\widetilde {w}}({\vec {x}})} and use the idempotency of Boolean variables ( x j ) q = x j ∀ q ≥ 1 {\displaystyle (x_{j})^{q}=x_{j}\forall q\geq 1} such that S ′ = b + ∑ k = 1 n x j w ~ j ( x → ) {\displaystyle S'=b+\sum _{k=1}^{n}x_{j}{\widetilde {w}}_{j}({\vec {x}})} can be written as S ′ ( x → ) = b + ∑ j w j x j + ∑ j < k w j k x j x k + ∑ j < k < l w j k l x j x k x l + . . . {\displaystyle S'({\vec {x}})=b+\sum _{j}w_{j}x_{j}+\sum _{j Read more →
Quadratic unconstrained binary optimization

Quadratic unconstrained binary optimization (QUBO), also known as unconstrained binary quadratic programming (UBQP), is a combinatorial optimization problem with a wide range of applications from finance and economics to machine learning. QUBO is an NP hard problem, and for many classical problems from theoretical computer science, like maximum cut, graph coloring and the partition problem, embeddings into QUBO have been formulated. Embeddings for machine learning models include support-vector machines, clustering and probabilistic graphical models. Moreover, due to its close connection to Ising models, QUBO constitutes a central problem class for adiabatic quantum computation, where it is solved through a physical process called quantum annealing. == Definition == Let B = { 0 , 1 } {\displaystyle \mathbb {B} =\lbrace 0,1\rbrace } the set of binary digits (or bits), then B n {\displaystyle \mathbb {B} ^{n}} is the set of binary vectors of fixed length n ∈ N {\displaystyle n\in \mathbb {N} } . Given a symmetric or upper triangular matrix Q ∈ R n × n {\displaystyle {\boldsymbol {Q}}\in \mathbb {R} ^{n\times n}} , whose entries Q i j {\displaystyle Q_{ij}} define a weight for each pair of indices i , j ∈ { 1 , … , n } {\displaystyle i,j\in \lbrace 1,\dots ,n\rbrace } , we can define the function f Q : B n → R {\displaystyle f_{\boldsymbol {Q}}:\mathbb {B} ^{n}\rightarrow \mathbb {R} } that assigns a value to each binary vector x {\displaystyle {\boldsymbol {x}}} through f Q ( x ) = x ⊺ Q x = ∑ i = 1 n ∑ j = 1 n Q i j x i x j . {\displaystyle f_{\boldsymbol {Q}}({\boldsymbol {x}})={\boldsymbol {x}}^{\intercal }{\boldsymbol {Qx}}=\sum _{i=1}^{n}\sum _{j=1}^{n}Q_{ij}x_{i}x_{j}.} Alternatively, the linear and quadratic parts can be separated as f Q ′ , q ( x ) = x ⊺ Q ′ x + q ⊺ x , {\displaystyle f_{{\boldsymbol {Q}}',{\boldsymbol {q}}}({\boldsymbol {x}})={\boldsymbol {x}}^{\intercal }{\boldsymbol {Q}}'{\boldsymbol {x}}+{\boldsymbol {q}}^{\intercal }{\boldsymbol {x}},} where Q ′ ∈ R n × n {\displaystyle {\boldsymbol {Q}}'\in \mathbb {R} ^{n\times n}} and q ∈ R n {\displaystyle {\boldsymbol {q}}\in \mathbb {R} ^{n}} . This is equivalent to the previous definition through Q = Q ′ + diag ⁡ [ q ] {\displaystyle {\boldsymbol {Q}}={\boldsymbol {Q}}'+\operatorname {diag} [{\boldsymbol {q}}]} using the diag operator, exploiting that x = x ⋅ x {\displaystyle x=x\cdot x} for all binary values x {\displaystyle x} . Intuitively, the weight Q i j {\displaystyle Q_{ij}} is added if both x i = 1 {\displaystyle x_{i}=1} and x j = 1 {\displaystyle x_{j}=1} . The QUBO problem consists of finding a binary vector x ∗ {\displaystyle {\boldsymbol {x}}^{}} that minimizes f Q {\displaystyle f_{\boldsymbol {Q}}} , i.e., ∀ x ∈ B n : f Q ( x ∗ ) ≤ f Q ( x ) {\displaystyle \forall {\boldsymbol {x}}\in \mathbb {B} ^{n}:~f_{\boldsymbol {Q}}({\boldsymbol {x}}^{})\leq f_{\boldsymbol {Q}}({\boldsymbol {x}})} . In general, x ∗ {\displaystyle {\boldsymbol {x}}^{}} is not unique, meaning there may be a set of minimizing vectors with equal value w.r.t. f Q {\displaystyle f_{\boldsymbol {Q}}} . The complexity of QUBO arises from the number of candidate binary vectors to be evaluated, as | B n | = 2 n {\displaystyle \left|\mathbb {B} ^{n}\right|=2^{n}} grows exponentially in n {\displaystyle n} . Sometimes, QUBO is defined as the problem of maximizing f Q {\displaystyle f_{\boldsymbol {Q}}} , which is equivalent to minimizing f − Q = − f Q {\displaystyle f_{-{\boldsymbol {Q}}}=-f_{\boldsymbol {Q}}} . == Properties == QUBO is scale invariant for positive factors α > 0 {\displaystyle \alpha >0} , which leave the optimum x ∗ {\displaystyle {\boldsymbol {x}}^{}} unchanged: f α Q ( x ) = x ⊺ ( α Q ) x = α ( x ⊺ Q x ) = α f Q ( x ) {\displaystyle f_{\alpha {\boldsymbol {Q}}}({\boldsymbol {x}})={\boldsymbol {x}}^{\intercal }(\alpha {\boldsymbol {Q}}){\boldsymbol {x}}=\alpha ({\boldsymbol {x}}^{\intercal }{\boldsymbol {Qx}})=\alpha f_{\boldsymbol {Q}}({\boldsymbol {x}})} . In its general form, QUBO is NP-hard and cannot be solved efficiently by any known polynomial-time algorithm. However, there are polynomially-solvable special cases, where Q {\displaystyle {\boldsymbol {Q}}} has certain properties, for example: If all coefficients are positive, the optimum is trivially x ∗ = ( 0 , … , 0 ) ⊺ {\displaystyle {\boldsymbol {x}}^{}=(0,\dots ,0)^{\intercal }} . Similarly, if all coefficients are negative, the optimum is x ∗ = ( 1 , … , 1 ) ⊺ {\displaystyle {\boldsymbol {x}}^{}=(1,\dots ,1)^{\intercal }} . If Q {\displaystyle {\boldsymbol {Q}}} is diagonal, the bits can be optimized independently, and the problem is solvable in O ( n ) {\displaystyle {\mathcal {O}}(n)} . The optimal variable assignments are simply x i ∗ = 1 {\displaystyle x_{i}^{}=1} if Q i i < 0 {\displaystyle Q_{ii}<0} , and x i ∗ = 0 {\displaystyle x_{i}^{}=0} otherwise. If all off-diagonal elements of Q {\displaystyle {\boldsymbol {Q}}} are non-positive, the corresponding QUBO problem is solvable in polynomial time. QUBO can be solved using integer linear programming solvers like CPLEX or Gurobi Optimizer. This is possible since QUBO can be reformulated as a linear constrained binary optimization problem. To achieve this, substitute the product x i x j {\displaystyle x_{i}x_{j}} by an additional binary variable z i j ∈ B {\displaystyle z_{ij}\in \mathbb {B} } and add the constraints x i ≥ z i j {\displaystyle x_{i}\geq z_{ij}} , x j ≥ z i j {\displaystyle x_{j}\geq z_{ij}} and x i + x j − 1 ≤ z i j {\displaystyle x_{i}+x_{j}-1\leq z_{ij}} . Note that z i j {\displaystyle z_{ij}} can also be relaxed to continuous variables within the bounds zero and one. == Applications == QUBO is a structurally simple, yet computationally hard optimization problem. It can be used to encode a wide range of optimization problems from various scientific areas. === Maximum Cut === Given a graph G = ( V , E ) {\displaystyle G=(V,E)} with vertex set V = { 1 , … , n } {\displaystyle V=\lbrace 1,\dots ,n\rbrace } and edges E ⊆ V × V {\displaystyle E\subseteq V\times V} , the maximum cut (max-cut) problem consists of finding two subsets S , T ⊆ V {\displaystyle S,T\subseteq V} with T = V ∖ S {\displaystyle T=V\setminus S} , such that the number of edges between S {\displaystyle S} and T {\displaystyle T} is maximized. The more general weighted max-cut problem assumes edge weights w i j ≥ 0 ∀ i , j ∈ V {\displaystyle w_{ij}\geq 0~\forall i,j\in V} , with ( i , j ) ∉ E ⇒ w i j = 0 {\displaystyle (i,j)\notin E\Rightarrow w_{ij}=0} , and asks for a partition S , T ⊆ V {\displaystyle S,T\subseteq V} that maximizes the sum of edge weights between S {\displaystyle S} and T {\displaystyle T} , i.e., max S ⊆ V ∑ i ∈ S , j ∉ S w i j . {\displaystyle \max _{S\subseteq V}\sum _{i\in S,j\notin S}w_{ij}.} By setting w i j = 1 {\displaystyle w_{ij}=1} for all ( i , j ) ∈ E {\displaystyle (i,j)\in E} this becomes equivalent to the original max-cut problem above, which is why we focus on this more general form in the following. For every vertex in i ∈ V {\displaystyle i\in V} we introduce a binary variable x i {\displaystyle x_{i}} with the interpretation x i = 0 {\displaystyle x_{i}=0} if i ∈ S {\displaystyle i\in S} and x i = 1 {\displaystyle x_{i}=1} if i ∈ T {\displaystyle i\in T} . As T = V ∖ S {\displaystyle T=V\setminus S} , every i {\displaystyle i} is in exactly one set, meaning there is a 1:1 correspondence between binary vectors x ∈ B n {\displaystyle {\boldsymbol {x}}\in \mathbb {B} ^{n}} and partitions of V {\displaystyle V} into two subsets. We observe that, for any i , j ∈ V {\displaystyle i,j\in V} , the expression x i ( 1 − x j ) + ( 1 − x i ) x j {\displaystyle x_{i}(1-x_{j})+(1-x_{i})x_{j}} evaluates to 1 if and only if i {\displaystyle i} and j {\displaystyle j} are in different subsets, equivalent to logical XOR. Let W ∈ R + n × n {\displaystyle {\boldsymbol {W}}\in \mathbb {R} _{+}^{n\times n}} with W i j = w i j ∀ i , j ∈ V {\displaystyle W_{ij}=w_{ij}~\forall i,j\in V} . By extending above expression to matrix-vector form we find that x ⊺ W ( 1 − x ) + ( 1 − x ) ⊺ W x = − 2 x ⊺ W x + ( W 1 + W ⊺ 1 ) ⊺ x {\displaystyle {\boldsymbol {x}}^{\intercal }{\boldsymbol {W}}({\boldsymbol {1}}-{\boldsymbol {x}})+({\boldsymbol {1}}-{\boldsymbol {x}})^{\intercal }{\boldsymbol {Wx}}=-2{\boldsymbol {x}}^{\intercal }{\boldsymbol {Wx}}+({\boldsymbol {W1}}+{\boldsymbol {W}}^{\intercal }{\boldsymbol {1}})^{\intercal }{\boldsymbol {x}}} is the sum of weights of all edges between S {\displaystyle S} and T {\displaystyle T} , where 1 = ( 1 , 1 , … , 1 ) ⊺ ∈ R n {\displaystyle {\boldsymbol {1}}=(1,1,\dots ,1)^{\intercal }\in \mathbb {R} ^{n}} . As this is a quadratic function over x {\displaystyle {\boldsymbol {x}}} , it is a QUBO problem whose parameter matrix we can read from above expression as Q = 2 W − diag ⁡ [ W 1 + W ⊺ 1 ] , {\displaystyle {\boldsymbol {Q}}=2{\boldsymbol {W}}-\operatorname {diag} [{\boldsymbol {W1}}+{\boldsymbol {W}}^{\intercal }{\bol
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Frequent pattern discovery

Frequent pattern discovery (or FP discovery, FP mining, or Frequent itemset mining) is part of knowledge discovery in databases, Massive Online Analysis, and data mining; it describes the task of finding the most frequent and relevant patterns in large datasets. The concept was first introduced for mining transaction databases. Frequent patterns are defined as subsets (itemsets, subsequences, or substructures) that appear in a data set with frequency no less than a user-specified or auto-determined threshold. == Techniques == Techniques for FP mining include: market basket analysis cross-marketing catalog design clustering classification recommendation systems For the most part, FP discovery can be done using association rule learning with particular algorithms Eclat, FP-growth and the Apriori algorithm. Other strategies include: Frequent subtree mining Structure mining Sequential pattern mining and respective specific techniques. Implementations exist for various machine learning systems or modules like MLlib for Apache Spark.
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Clips (software)

Clips is a discontinued mobile video editing software application created by Apple Inc. It was released onto the iOS App Store on April 6, 2017, for free. Initially, it was only available on 64-bit devices running iOS 10.3 or later; as of version 3.1.3, it requires iOS 16.0 or later. Apple describes it as an app for "making and sharing fun videos with text, effects, graphics, and more.". Its final release was on May 9, 2024 before was removed from the App Store on October 10, 2025. == Features == After launching of the app, the user sees the view of the front-facing camera. The app allows the user to create a new clip by tapping on a red record button, or use photos or videos from the device's photo library. Once a clip is recorded, it can be added to a project timeline shown at the bottom of the screen. The user can share their project on social media platforms. The user can also add filters and effects to the project. "Live Titles" (available in several styles) can also be created by dictating to the device.
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Confirmatory blockmodeling

Confirmatory blockmodeling is a deductive approach in blockmodeling, where a blockmodel (or part of it) is prespecify before the analysis, and then the analysis is fit to this model. When only a part of analysis is prespecify (like individual cluster(s) or location of the block types), it is called partially confirmatory blockmodeling. This is so-called indirect approach, where the blockmodeling is done on the blockmodel fitting (e.g., a priori hypothesized blockmodel). Opposite approach to the confirmatory blockmodeling is an inductive exploratory blockmodeling.
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Prescription monitoring program

In the United States, prescription monitoring programs (PMPs) or prescription drug monitoring programs (PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs. PMPs are meant to help prevent adverse drug-related events such as opioid overdoses, drug diversion, and substance abuse by decreasing the amount and/or frequency of opioid prescribing, and by identifying those patients who are obtaining prescriptions from multiple providers (i.e., "doctor shopping") or those physicians overprescribing opioids. Most US health care workers support the idea of PMPs, which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments. The database, whose use is required by State law, typically requires prescribers and pharmacies dispensing controlled substances to register with their respective state PMPs and (for pharmacies and providers who dispense from their offices) to report the dispensation of such prescriptions to an electronic online database. The majority of PMPs are authorized to notify law enforcement agencies or licensing boards or physicians when a prescriber, or patients receiving prescriptions, exceed thresholds established by the state or prescription recipient exceeds thresholds established by the State. All states have implemented PDMPs, although evidence for the effectiveness of these programs is mixed. While prescription of opioids has decreased with PMP use, overdose deaths in many states have actually increased, with those states sharing data with neighboring jurisdictions or requiring reporting of more drugs experiencing highest increases in deaths. This may be because those declined opioid prescriptions turn to street drugs, whose potency and contaminants carry greater overdose risk. == History == Prescription drug monitoring programs, or PDMPs, are an example of one initiative proposed to alleviate effects of the opioid crisis. The programs are designed to restrict prescription drug abuse by limiting a patient's ability to obtain similar prescriptions from multiple providers (i.e. “doctor shopping”) and reducing diversion of controlled substances. This is meant to reduce risk of fatal overdose caused by high doses of opioids or interactions between opioids and benzodiazepenes, and to enable better decision making on the part of healthcare providers who may be unaware of a patient's prescription drug use, history or other prescriptions. PDMPs have been implemented in state legislations since 1939 in California, a time before electronic medical records, though implementation rose alongside increased awareness of overprescribing of opioids and overdose. A later New York state program was struck down by the U.S. Supreme Court in Whalen v. Roe. But, by 2019, 49 states, the District of Columbia, and Guam had enacted PDMP legislation. In 2021 Missouri, the last State to not use a PMP, adopted legislation to create one. PMPs are constantly being updated to increase speed of data collection, sharing of data across States, and ease of interpretation. This is being done by integrating PDMP reports with other health information technologies such as health information exchanges (HIE), electronic health record (EHR) systems, and/ or pharmacy dispensing software systems. One program that has been implemented in nine states is called the PDMP Electronic Health Records Integration and Interoperability Expansion, also known as PEHRIIE. Another software, marketed by Bamboo Health and integrated with PMPs in 43 states, uses an algorithm to track factors thought to increase risk of diversion, abuse or overdose, and assigns patients a three digit score based on presumed indicators of risk. While some studies have suggested that PDMP-HIT integration and sharing of interstate data brings benefits such as reduced opioid-related inpatient morbidity, others have found no or negative impact on mortality compared to states without PMP data sharing. Patient and media reports suggest need for testing and evaluation of algorithmic software used to score risk, with some patients reporting denial of prescriptions without c explanation or clarity of data. == Goals == Most health care workers support PMPs which intend to assist physicians, physician assistants, nurse practitioners, dentists and other prescribers, the pharmacists, chemists and support staff of dispensing establishments, as well as law-enforcement agencies. The collaboration supports the legitimate medical use of controlled substances while limiting their abuse and diversion. Pharmacies dispensing controlled substances and prescribers typically must register with their respective state PMPs and (for pharmacies and providers who dispense controlled substances from their offices) report the dispensation to an electronic online database. Some pharmacy software can submit these reports automatically to multiple states. == Usage == === List of programs by state === === Software systems === NarxCare is a prescription drug monitoring program (PDMP) run by Bamboo Health. Bamboo Health was formerly known as Appriss. It is widely used across the United States by pharmacies including Rite Aid as well as those at Walmart and Sam’s Club. The NarxCare software allows doctors to view data about a patient, combining data from the prescription registries of various U.S. states to make the registries interoperable nationally. It also uses machine learning to generate an "Overdose Risk Score" that potentially includes EMS and criminal justice data; these scores have been criticized by researchers and patient advocates for the lack of transparency in the process as well as the potential for disparate treatment of women and minority groups. Advertised as an "analytics tool and care management platform", the NarxCare software allows doctors to view data about a patient including how many pharmacies they have visited and the combinations of medication they are prescribed. It combines data from the prescription registries of various U.S. states, making the registries interoperable nationally. It additionally uses machine learning to generate various three-digit "risk scores" and an overall "Overdose Risk Score", collectively referred to as Narx Scores, in a process that potentially includes EMS and criminal justice data as well as court records. == Controversy == Many doctors and researchers support the idea of PDMPs as a tool in combatting the opioid epidemic. Opioid prescribing, opioid diversion and supply, opioid misuse, and opioid-related morbidity and mortality are common elements in data entered into PDMPs. Prescription Monitoring Programs are purported to offer economic benefits for the states who implement them by decreasing overall health care costs, lost productivity, and investigation times. However, there are many studies that conclude the impact of PDMPs is unclear. While use of PMPs has been accompanied by decrease in opioid prescribing, few analyses consider corresponding use of street opioids, extramedical use, or diversion, which might provide a more holistic method for evaluation of PMP intent and efficacy. Evidence for PDMP impact on fatal overdoses is decidedly mixed, with multiple studies finding increased overdose rates in some states, decreases in others, or no clear impact. Interestingly, an increase in heroin overdoses after PDMP implementation has been commonly reported, presumably as denial of prescription opioids sends patients in search of street drugs. Narx Scores have been criticized by researchers and patient advocates for the lack of transparency in the generation process as well as the potential for disparate treatment of women and minority groups. Writing in Duke Law Journal, Jennifer Oliva stated that "black-box algorithms" are used to generate the scores.
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Optimal discriminant analysis and classification tree analysis

Optimal Discriminant Analysis (ODA) and the related classification tree analysis (CTA) are exact statistical methods that maximize predictive accuracy. For any specific sample and exploratory or confirmatory hypothesis, optimal discriminant analysis (ODA) identifies the statistical model that yields maximum predictive accuracy, assesses the exact Type I error rate, and evaluates potential cross-generalizability. Optimal discriminant analysis may be applied to > 0 dimensions, with the one-dimensional case being referred to as UniODA and the multidimensional case being referred to as MultiODA. Optimal discriminant analysis is an alternative to ANOVA (analysis of variance) and regression analysis.
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Information retrieval

Information retrieval (IR) in computing and information science is the task of identifying and retrieving information system resources that are relevant to an information need. The information need can be specified in the form of a search query. In the case of document retrieval, queries can be based on full-text or other content-based indexing. Information retrieval is the science of searching for information in a document, searching for documents themselves, and also searching for the metadata that describes data, and for databases of texts, images, or sounds. Cross-modal retrieval implies retrieval across modalities. Automated information retrieval systems are used to reduce what has been called information overload. An IR system is a software system that provides access to books, journals, and other documents, as well as storing and managing those documents. Web search engines are the most visible IR applications. == Overview == An information retrieval process begins when a user enters a query into the system. Queries are formal statements of information needs, for example search strings in web search engines. In information retrieval, a query does not uniquely identify a single object in the collection. Instead, several objects may match the query, perhaps with different degrees of relevance. An object is an entity that is represented by information in a content collection or database. User queries are matched against the database information. However, as opposed to classical SQL queries of a database, in information retrieval the results returned may or may not match the query, so results are typically ranked. This ranking of results is a key difference of information retrieval searching compared to database searching. Depending on the application the data objects may be, for example, text documents, images, audio, mind maps or videos. Often the documents themselves are not kept or stored directly in the IR system, but are instead represented in the system by document surrogates or metadata. Most IR systems compute a numeric score on how well each object in the database matches the query, and rank the objects according to this value. The top ranking objects are then shown to the user. The process may then be iterated if the user wishes to refine the query. == History == there is ... a machine called the Univac ... whereby letters and figures are coded as a pattern of magnetic spots on a long steel tape. By this means the text of a document, preceded by its subject code symbol, can be recorded ... the machine ... automatically selects and types out those references which have been coded in any desired way at a rate of 120 words a minute The idea of using computers to search for relevant pieces of information was popularized in the article As We May Think by Vannevar Bush in 1945. It would appear that Bush was inspired by patents for a 'statistical machine' – filed by Emanuel Goldberg in the 1920s and 1930s – that searched for documents stored on film. The first description of a computer searching for information was described by Holmstrom in 1948, detailing an early mention of the Univac computer. Automated information retrieval systems were introduced in the 1950s: one even featured in the 1957 romantic comedy Desk Set. In the 1960s, the first large information retrieval research group was formed by Gerard Salton at Cornell. By the 1970s several different retrieval techniques had been shown to perform well on small text corpora such as the Cranfield collection (several thousand documents). Large-scale retrieval systems, such as the Lockheed Dialog system, came into use early in the 1970s. In 1992, the US Department of Defense along with the National Institute of Standards and Technology (NIST), cosponsored the Text Retrieval Conference (TREC) as part of the TIPSTER text program. The aim of this was to look into the information retrieval community by supplying the infrastructure that was needed for evaluation of text retrieval methodologies on a very large text collection. This catalyzed research on methods that scale to huge corpora. The introduction of web search engines has boosted the need for very large scale retrieval systems even further. By the late 1990s, the rise of the World Wide Web fundamentally transformed information retrieval. While early search engines such as AltaVista (1995) and Yahoo! (1994) offered keyword-based retrieval, they were limited in scale and ranking refinement. The breakthrough came in 1998 with the founding of Google, which introduced the PageRank algorithm, using the web's hyperlink structure to assess page importance and improve relevance ranking. During the 2000s, web search systems evolved rapidly with the integration of machine learning techniques. These systems began to incorporate user behavior data (e.g., click-through logs), query reformulation, and content-based signals to improve search accuracy and personalization. In 2009, Microsoft launched Bing, introducing features that would later incorporate semantic web technologies through the development of its Satori knowledge base. Academic analysis have highlighted Bing's semantic capabilities, including structured data use and entity recognition, as part of a broader industry shift toward improving search relevance and understanding user intent through natural language processing. A major leap occurred in 2018, when Google deployed BERT (Bidirectional Encoder Representations from Transformers) to better understand the contextual meaning of queries and documents. This marked one of the first times deep neural language models were used at scale in real-world retrieval systems. BERT's bidirectional training enabled a more refined comprehension of word relationships in context, improving the handling of natural language queries. Because of its success, transformer-based models gained traction in academic research and commercial search applications. Simultaneously, the research community began exploring neural ranking models that outperformed traditional lexical-based methods. Long-standing benchmarks such as the Text REtrieval Conference (TREC), initiated in 1992, and more recent evaluation frameworks Microsoft MARCO(MAchine Reading COmprehension) (2019) became central to training and evaluating retrieval systems across multiple tasks and domains. MS MARCO has also been adopted in the TREC Deep Learning Tracks, where it serves as a core dataset for evaluating advances in neural ranking models within a standardized benchmarking environment. As deep learning became integral to information retrieval systems, researchers began to categorize neural approaches into three broad classes: sparse, dense, and hybrid models. Sparse models, including traditional term-based methods and learned variants like SPLADE, rely on interpretable representations and inverted indexes to enable efficient exact term matching with added semantic signals. Dense models, such as dual-encoder architectures like ColBERT, use continuous vector embeddings to support semantic similarity beyond keyword overlap. Hybrid models aim to combine the advantages of both, balancing the lexical (token) precision of sparse methods with the semantic depth of dense models. This way of categorizing models balances scalability, relevance, and efficiency in retrieval systems. As IR systems increasingly rely on deep learning, concerns around bias, fairness, and explainability have also come to the picture. Research is now focused not just on relevance and efficiency, but on transparency, accountability, and user trust in retrieval algorithms. == Applications == Areas where information retrieval techniques are employed include (the entries are in alphabetical order within each category): === General applications === Digital libraries Information filtering Recommender systems Media search Blog search Image retrieval 3D retrieval Music retrieval News search Speech retrieval Video retrieval Search engines Site search Desktop search Enterprise search Federated search Mobile search Social search Web search === Domain-specific applications === Expert search finding Genomic information retrieval Geographic information retrieval Information retrieval for chemical structures Information retrieval in software engineering Legal information retrieval Vertical search === Other retrieval methods === Methods/Techniques in which information retrieval techniques are employed include: Cross-modal retrieval Adversarial information retrieval Automatic summarization Multi-document summarization Compound term processing Cross-lingual retrieval Document classification Spam filtering Question answering == Model types == In order to effectively retrieve relevant documents by IR strategies, the documents are typically transformed into a suitable representation. Each retrieval strategy incorporates a specific model for its document representation purposes. The picture on the right illustrates the relationship of som
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Mutation (evolutionary algorithm)

Mutation is a genetic operator used to maintain genetic diversity of the chromosomes of a population of an evolutionary algorithm (EA), including genetic algorithms in particular. It is analogous to biological mutation. The classic example of a mutation operator of a binary coded genetic algorithm (GA) involves a probability that an arbitrary bit in a genetic sequence will be flipped from its original state. A common method of implementing the mutation operator involves generating a random variable for each bit in a sequence. This random variable tells whether or not a particular bit will be flipped. This mutation procedure, based on the biological point mutation, is called single point mutation. Other types of mutation operators are commonly used for representations other than binary, such as floating-point encodings or representations for combinatorial problems. The purpose of mutation in EAs is to introduce diversity into the sampled population. Mutation operators are used in an attempt to avoid local minima by preventing the population of chromosomes from becoming too similar to each other, thus slowing or even stopping convergence to the global optimum. This reasoning also leads most EAs to avoid only taking the fittest of the population in generating the next generation, but rather selecting a random (or semi-random) set with a weighting toward those that are fitter. The following requirements apply to all mutation operators used in an EA: every point in the search space must be reachable by one or more mutations. there must be no preference for parts or directions in the search space (no drift). small mutations should be more probable than large ones. For different genome types, different mutation types are suitable. Some mutations are Gaussian, Uniform, Zigzag, Scramble, Insertion, Inversion, Swap, and so on. An overview and more operators than those presented below can be found in the introductory book by Eiben and Smith or in. == Bit string mutation == The mutation of bit strings ensue through bit flips at random positions. Example: The probability of a mutation of a bit is 1 l {\displaystyle {\frac {1}{l}}} , where l {\displaystyle l} is the length of the binary vector. Thus, a mutation rate of 1 {\displaystyle 1} per mutation and individual selected for mutation is reached. == Mutation of real numbers == Many EAs, such as the evolution strategy or the real-coded genetic algorithms, work with real numbers instead of bit strings. This is due to the good experiences that have been made with this type of coding. The value of a real-valued gene can either be changed or redetermined. A mutation that implements the latter should only ever be used in conjunction with the value-changing mutations and then only with comparatively low probability, as it can lead to large changes. In practical applications, the respective value range of the decision variables to be changed of the optimisation problem to be solved is usually limited. Accordingly, the values of the associated genes are each restricted to an interval [ x min , x max ] {\displaystyle [x_{\min },x_{\max }]} . Mutations may or may not take these restrictions into account. In the latter case, suitable post-treatment is then required as described below. === Mutation without consideration of restrictions === A real number x {\displaystyle x} can be mutated using normal distribution N ( 0 , σ ) {\displaystyle {\mathcal {N}}(0,\sigma )} by adding the generated random value to the old value of the gene, resulting in the mutated value x ′ {\displaystyle x'} : x ′ = x + N ( 0 , σ ) {\displaystyle x'=x+{\mathcal {N}}(0,\sigma )} In the case of genes with a restricted range of values, it is a good idea to choose the step size of the mutation σ {\displaystyle \sigma } so that it reasonably fits the range [ x min , x max ] {\displaystyle [x_{\min },x_{\max }]} of the gene to be changed, e.g.: σ = x max − x min 6 {\displaystyle \sigma ={\frac {x_{\text{max}}-x_{\text{min}}}{6}}} The step size can also be adjusted to the smaller permissible change range depending on the current value. In any case, however, it is likely that the new value x ′ {\displaystyle x'} of the gene will be outside the permissible range of values. Such a case must be considered a lethal mutation, since the obvious repair by using the respective violated limit as the new value of the gene would lead to a drift. This is because the limit value would then be selected with the entire probability of the values beyond the limit of the value range. The evolution strategy works with real numbers and mutation based on normal distribution. The step sizes are part of the chromosome and are subject to evolution together with the actual decision variables. === Mutation with consideration of restrictions === One possible form of changing the value of a gene while taking its value range [ x min , x max ] {\displaystyle [x_{\min },x_{\max }]} into account is the mutation relative parameter change of the evolutionary algorithm GLEAM (General Learning Evolutionary Algorithm and Method), in which, as with the mutation presented earlier, small changes are more likely than large ones. First, an equally distributed decision is made as to whether the current value x {\displaystyle x} should be increased or decreased and then the corresponding total change interval is determined. Without loss of generality, an increase is assumed for the explanation and the total change interval is then [ x , x max ] {\displaystyle [x,x_{\max }]} . It is divided into k {\displaystyle k} sub-areas of equal size with the width δ {\displaystyle \delta } , from which k {\displaystyle k} sub-change intervals of different size are formed: i {\displaystyle i} -th sub-change interval: [ x , x + δ ⋅ i ] {\displaystyle [x,x+\delta \cdot i]} with δ = ( x max − x ) k {\displaystyle \delta ={\frac {(x_{\text{max}}-x)}{k}}} and i = 1 , … , k {\displaystyle i=1,\dots ,k} Subsequently, one of the k {\displaystyle k} sub-change intervals is selected in equal distribution and a random number, also equally distributed, is drawn from it as the new value x ′ {\displaystyle x'} of the gene. The resulting summed probabilities of the sub-change intervals result in the probability distribution of the k {\displaystyle k} sub-areas shown in the adjacent figure for the exemplary case of k = 10 {\displaystyle k=10} . This is not a normal distribution as before, but this distribution also clearly favours small changes over larger ones. This mutation for larger values of k {\displaystyle k} , such as 10, is less well suited for tasks where the optimum lies on one of the value range boundaries. This can be remedied by significantly reducing k {\displaystyle k} when a gene value approaches its limits very closely. === Common properties === For both mutation operators for real-valued numbers, the probability of an increase and decrease is independent of the current value and is 50% in each case. In addition, small changes are considerably more likely than large ones. For mixed-integer optimization problems, rounding is usually used. == Mutation of permutations == Mutations of permutations are specially designed for genomes that are themselves permutations of a set. These are often used to solve combinatorial tasks. In the two mutations presented, parts of the genome are rotated or inverted. === Rotation to the right === The presentation of the procedure is illustrated by an example on the right: === Inversion === The presentation of the procedure is illustrated by an example on the right: === Variants with preference for smaller changes === The requirement raised at the beginning for mutations, according to which small changes should be more probable than large ones, is only inadequately fulfilled by the two permutation mutations presented, since the lengths of the partial lists and the number of shift positions are determined in an equally distributed manner. However, the longer the partial list and the shift, the greater the change in gene order. This can be remedied by the following modifications. The end index j {\displaystyle j} of the partial lists is determined as the distance d {\displaystyle d} to the start index i {\displaystyle i} : j = ( i + d ) mod | P 0 | {\displaystyle j=(i+d){\bmod {\left|P_{0}\right|}}} where d {\displaystyle d} is determined randomly according to one of the two procedures for the mutation of real numbers from the interval [ 0 , | P 0 | − 1 ] {\displaystyle \left[0,\left|P_{0}\right|-1\right]} and rounded. For the rotation, k {\displaystyle k} is determined similarly to the distance d {\displaystyle d} , but the value 0 {\displaystyle 0} is forbidden. For the inversion, note that i ≠ j {\displaystyle i\neq j} must hold, so for d {\displaystyle d} the value 0 {\displaystyle 0} must be excluded.
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Abess

abess (Adaptive Best Subset Selection, also ABESS) is a machine learning method designed to address the problem of best subset selection. It aims to determine which features or variables are crucial for optimal model performance when provided with a dataset and a prediction task. abess was introduced by Zhu in 2020 and it dynamically selects the appropriate model size adaptively, eliminating the need for selecting regularization parameters. abess is applicable in various statistical and machine learning tasks, including linear regression, the Single-index model, and other common predictive models. abess can also be applied in biostatistics. == Basic Form == The basic form of abess is employed to address the optimal subset selection problem in general linear regression. abess is an l 0 {\displaystyle l_{0}} method, it is characterized by its polynomial time complexity and the property of providing both unbiased and consistent estimates. In the context of linear regression, assuming we have knowledge of n {\displaystyle n} independent samples ( x i , y i ) , i = 1 , … , n {\displaystyle (x_{i},y_{i}),i=1,\ldots ,n} , where x i ∈ R p × 1 {\displaystyle x_{i}\in \mathbb {R} ^{p\times 1}} and y i ∈ R {\displaystyle y_{i}\in \mathbb {R} } , we define X = ( x 1 , … , x n ) ⊤ {\displaystyle X=(x_{1},\ldots ,x_{n})^{\top }} and y = ( y 1 , … , y n ) ⊤ {\displaystyle y=(y_{1},\ldots ,y_{n})^{\top }} . The following equation represents the general linear regression model: y = X β + ε . {\displaystyle y=X\beta +\varepsilon .} To obtain appropriate parameters β {\displaystyle \beta } , one can consider the loss function for linear regression: L n LR ( β ; X , y ) = 1 2 n ‖ y − X β ‖ 2 2 . {\displaystyle {\mathcal {L}}_{n}^{\text{LR}}(\beta ;X,y)={\frac {1}{2n}}\|y-X\beta \|_{2}^{2}.} In abess, the initial focus is on optimizing the loss function under the l 0 {\displaystyle l_{0}} constraint. That is, we consider the following problem: min β ∈ R p × 1 L n LR ( β ; X , y ) , subject to ‖ β ‖ 0 ≤ s , {\displaystyle \min _{\beta \in \mathbb {R} ^{p\times 1}}{\mathcal {L}}_{n}^{\text{LR}}(\beta ;X,y),{\text{ subject to }}\|\beta \|_{0}\leq s,} where s {\displaystyle s} represents the desired size of the support set, and ‖ β ‖ 0 = ∑ i = 1 p I ( β i ≠ 0 ) {\displaystyle \|\beta \|_{0}=\sum _{i=1}^{p}{\mathcal {I}}_{(\beta _{i}\neq 0)}} is the l 0 {\displaystyle l_{0}} norm of the vector. To address the optimization problem described above, abess iteratively exchanges an equal number of variables between the active set and the inactive set. In each iteration, the concept of sacrifice is introduced as follows: For j in the active set ( j ∈ A ^ {\displaystyle j\in {\hat {\mathcal {A}}}} ): ξ j = L n LR ( β ^ A ∖ { j } ) − L n LR ( β ^ A ) = X j ⊤ X j 2 n ( β ^ j ) 2 {\displaystyle \xi _{j}={\mathcal {L}}_{n}^{\text{LR}}\left({\hat {\boldsymbol {\beta }}}^{{\mathcal {A}}\backslash \{j\}}\right)-{\mathcal {L}}_{n}^{\text{LR}}\left({\hat {\boldsymbol {\beta }}}^{\mathcal {A}}\right)={\frac {{\boldsymbol {X}}_{j}^{\top }{\boldsymbol {X}}_{j}}{2n}}\left({\hat {\beta }}_{j}\right)^{2}} For j in the inactive set ( j ∉ A ^ {\displaystyle j\notin {\hat {\mathcal {A}}}} ): ξ j = L n LR ( β ^ A ) − L n LR ( β ^ A + t ^ { j } ) = X j ⊤ X j 2 n ( d ^ j X j ⊤ X j / n ) 2 {\displaystyle \xi _{j}={\mathcal {L}}_{n}^{\text{LR}}\left({\hat {\boldsymbol {\beta }}}^{\mathcal {A}}\right)-{\mathcal {L}}_{n}^{\text{LR}}\left({\hat {\boldsymbol {\beta }}}^{\mathcal {A}}+{\hat {\boldsymbol {t}}}^{\{j\}}\right)={\frac {{\boldsymbol {X}}_{j}^{\top }{\boldsymbol {X}}_{j}}{2n}}\left({\frac {{\hat {\mathrm {d} }}_{j}}{{\boldsymbol {X}}_{j}^{\top }{\boldsymbol {X}}_{j}/n}}\right)^{2}} Here are the key elements in the above equations: β ^ A {\displaystyle {\hat {\beta }}^{\mathcal {A}}} : This represents the estimate of β {\displaystyle \beta } obtained in the previous iteration. A ^ {\displaystyle {\hat {\mathcal {A}}}} : It denotes the estimated active set from the previous iteration. β ^ A ∖ { j } {\displaystyle {\hat {\boldsymbol {\beta }}}^{{\mathcal {A}}\backslash \{j\}}} : This is a vector where the j-th element is set to 0, while the other elements are the same as β ^ A {\displaystyle {\hat {\beta }}^{\mathcal {A}}} . t ^ { j } = arg ⁡ min t L n LR ( β ^ A + t { j } ) {\displaystyle {\hat {\boldsymbol {t}}}^{\{j\}}=\arg \min _{t}{\mathcal {L}}_{n}^{\text{LR}}\left({\hat {\boldsymbol {\beta }}}^{\mathcal {A}}+{\boldsymbol {t}}^{\{j\}}\right)} : Here, t { j } {\displaystyle t^{\{j\}}} represents a vector where all elements are 0 except the j-th element. d ^ j = X j ⊤ ( y − X β ^ ) / n {\displaystyle {\hat {d}}_{j}={\boldsymbol {X}}_{j}^{\top }({\boldsymbol {y}}-{\boldsymbol {X}}{\hat {\boldsymbol {\beta }}})/n} : This is calculated based on the equation mentioned. The iterative process involves exchanging variables, with the aim of minimizing the sacrifices in the active set while maximizing the sacrifices in the inactive set during each iteration. This approach allows abess to efficiently search for the optimal feature subset. In abess, select an appropriate s max {\displaystyle s_{\max }} and optimize the above problem for active sets size s = 1 , … , s max {\displaystyle s=1,\ldots ,s_{\max }} using the information criterion GIC = n log ⁡ L n LR + s log ⁡ p log ⁡ log ⁡ n , {\displaystyle {\text{GIC}}=n\log {\mathcal {L}}_{n}^{\text{LR}}+s\log p\log \log n,} to adaptively choose the appropriate active set size s {\displaystyle s} and obtain its corresponding abess estimator. == Generalizations == The splicing algorithm in abess can be employed for subset selection in other models. === Distribution-Free Location-Scale Regression === In 2023, Siegfried extends abess to the case of Distribution-Free and Location-Scale. Specifically, it considers the optimization problem max ϑ ∈ R P , β ∈ R J , γ ∈ R J ∑ i = 1 N ℓ i ( ϑ , x i ⊤ β , exp ⁡ ( x i ⊤ γ ) − 1 ) , {\displaystyle \max _{{\boldsymbol {\vartheta }}\in \mathbb {R} ^{P},{\boldsymbol {\beta }}\in \mathbb {R} ^{J},{\boldsymbol {\gamma }}\in \mathbb {R} ^{J}}\sum _{i=1}^{N}\ell _{i}\left({\boldsymbol {\vartheta }},{\boldsymbol {x}}_{i}^{\top }{\boldsymbol {\beta }},{\sqrt {\exp \left({\boldsymbol {x}}_{i}^{\top }{\boldsymbol {\gamma }}\right)}}^{-1}\right),} subject to ‖ ( β ⊤ , γ ⊤ ) ⊤ ‖ 0 ≤ s , {\displaystyle \left\|\left({\boldsymbol {\beta }}^{\top },{\boldsymbol {\gamma }}^{\top }\right)^{\top }\right\|_{0}\leq s,} where ℓ i {\displaystyle \ell _{i}} is a loss function, ϑ {\displaystyle {\boldsymbol {\vartheta }}} is a parameter vector, β {\displaystyle {\boldsymbol {\beta }}} and γ {\displaystyle {\boldsymbol {\gamma }}} are vectors, and x i {\displaystyle {\boldsymbol {x}}_{i}} is a data vector. This approach, demonstrated across various applications, enables parsimonious regression modeling for arbitrary outcomes while maintaining interpretability through innovative subset selection procedures. === Groups Selection === In 2023, Zhang applied the splicing algorithm to group selection, optimizing the following model: min β ∈ R p L n LR ( β ; X , y ) subject to ∑ j = 1 J I ( ‖ β G j ‖ 2 ≠ 0 ) ≤ s {\displaystyle \min _{{\boldsymbol {\beta }}\in \mathbb {R} ^{p}}{\mathcal {L}}_{n}^{\text{LR}}(\beta ;X,y){\text{ subject to }}\sum _{j=1}^{J}I\left(\|{\boldsymbol {\beta }}_{G_{j}}\|_{2}\neq 0\right)\leq s} Here are the symbols involved: J {\displaystyle J} : Total number of feature groups, representing the existence of J {\displaystyle J} non-overlapping feature groups in the dataset. G j {\displaystyle G_{j}} : Index set for the j {\displaystyle j} -th feature group, where j {\displaystyle j} ranges from 1 to J {\displaystyle J} , representing the feature grouping structure in the data. s {\displaystyle s} : Model size, a positive integer determined from the data, limiting the number of selected feature groups. === Regression with Corrupted Data === Zhang applied the splicing algorithm to handle corrupted data. Corrupted data refers to information that has been disrupted or contains errors during the data collection or recording process. This interference may include sensor inaccuracies, recording errors, communication issues, or other external disturbances, leading to inaccurate or distorted observations within the dataset. === Single Index Models === In 2023, Tang applied the splicing algorithm to optimal subset selection in the Single-index model. The form of the Single Index Model (SIM) is given by y i = g ( b ⊤ x i , e i ) , i = 1 , … , n , {\displaystyle y_{i}=g({\boldsymbol {b}}^{\top }{\boldsymbol {x}}_{i},e_{i}),\quad i=1,\ldots ,n,} where b {\displaystyle {\boldsymbol {b}}} is the parameter vector, e i {\displaystyle e_{i}} is the error term. The corresponding loss function is defined as l n ( β ) = ∑ i = 1 n ( r i n − 1 2 − x i ⊤ β ) 2 , {\displaystyle l_{n}({\boldsymbol {\beta }})=\sum _{i=1}^{n}\left({\frac {r_{i}}{n}}-{\frac {1}{2}}-{\boldsymbol {x}}_{i}^{\top }{\boldsymbol {\beta }}\right)^{2},} where r {\disp
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Proper generalized decomposition

The proper generalized decomposition (PGD) is an iterative numerical method for solving boundary value problems (BVPs), that is, partial differential equations constrained by a set of boundary conditions, such as the Poisson's equation or the Laplace's equation. The PGD algorithm computes an approximation of the solution of the BVP by successive enrichment. This means that, in each iteration, a new component (or mode) is computed and added to the approximation. In principle, the more modes obtained, the closer the approximation is to its theoretical solution. Unlike POD principal components, PGD modes are not necessarily orthogonal to each other. By selecting only the most relevant PGD modes, a reduced order model of the solution is obtained. Because of this, PGD is considered a dimensionality reduction algorithm. == Description == The proper generalized decomposition is a method characterized by a variational formulation of the problem, a discretization of the domain in the style of the finite element method, the assumption that the solution can be approximated as a separate representation and a numerical greedy algorithm to find the solution. === Variational formulation === In the Proper Generalized Decomposition method, the variational formulation involves translating the problem into a format where the solution can be approximated by minimizing (or sometimes maximizing) a functional. A functional is a scalar quantity that depends on a function, which in this case, represents our problem. The most commonly implemented variational formulation in PGD is the Bubnov-Galerkin method. This method is chosen for its ability to provide an approximate solution to complex problems, such as those described by partial differential equations (PDEs). In the Bubnov-Galerkin approach, the idea is to project the problem onto a space spanned by a finite number of basis functions. These basis functions are chosen to approximate the solution space of the problem. In the Bubnov-Galerkin method, we seek an approximate solution that satisfies the integral form of the PDEs over the domain of the problem. This is different from directly solving the differential equations. By doing so, the method transforms the problem into finding the coefficients that best fit this integral equation in the chosen function space. While the Bubnov-Galerkin method is prevalent, other variational formulations are also used in PGD, depending on the specific requirements and characteristics of the problem, such as: Petrov-Galerkin Method: This method is similar to the Bubnov-Galerkin approach but differs in the choice of test functions. In the Petrov-Galerkin method, the test functions (used to project the residual of the differential equation) are different from the trial functions (used to approximate the solution). This can lead to improved stability and accuracy for certain types of problems. Collocation Method: In collocation methods, the differential equation is satisfied at a finite number of points in the domain, known as collocation points. This approach can be simpler and more direct than the integral-based methods like Galerkin's, but it may also be less stable for some problems. Least Squares Method: This approach involves minimizing the square of the residual of the differential equation over the domain. It is particularly useful when dealing with problems where traditional methods struggle with stability or convergence. Mixed Finite Element Method: In mixed methods, additional variables (such as fluxes or gradients) are introduced and approximated along with the primary variable of interest. This can lead to more accurate and stable solutions for certain problems, especially those involving incompressibility or conservation laws. Discontinuous Galerkin Method: This is a variant of the Galerkin method where the solution is allowed to be discontinuous across element boundaries. This method is particularly useful for problems with sharp gradients or discontinuities. === Domain discretization === The discretization of the domain is a well defined set of procedures that cover (a) the creation of finite element meshes, (b) the definition of basis function on reference elements (also called shape functions) and (c) the mapping of reference elements onto the elements of the mesh. === Separate representation === PGD assumes that the solution u of a (multidimensional) problem can be approximated as a separate representation of the form u ≈ u N ( x 1 , x 2 , … , x d ) = ∑ i = 1 N X 1 i ( x 1 ) ⋅ X 2 i ( x 2 ) ⋯ X d i ( x d ) , {\displaystyle \mathbf {u} \approx \mathbf {u} ^{N}(x_{1},x_{2},\ldots ,x_{d})=\sum _{i=1}^{N}\mathbf {X_{1}} _{i}(x_{1})\cdot \mathbf {X_{2}} _{i}(x_{2})\cdots \mathbf {X_{d}} _{i}(x_{d}),} where the number of addends N and the functional products X1(x1), X2(x2), ..., Xd(xd), each depending on a variable (or variables), are unknown beforehand. === Greedy algorithm === The solution is sought by applying a greedy algorithm, usually the fixed point algorithm, to the weak formulation of the problem. For each iteration i of the algorithm, a mode of the solution is computed. Each mode consists of a set of numerical values of the functional products X1(x1), ..., Xd(xd), which enrich the approximation of the solution. Due to the greedy nature of the algorithm, the term 'enrich' is used rather than 'improve', since some modes may actually worsen the approach. The number of computed modes required to obtain an approximation of the solution below a certain error threshold depends on the stopping criterion of the iterative algorithm. == Features == PGD is suitable for solving high-dimensional problems, since it overcomes the limitations of classical approaches. In particular, PGD avoids the curse of dimensionality, as solving decoupled problems is computationally much less expensive than solving multidimensional problems. Therefore, PGD enables to re-adapt parametric problems into a multidimensional framework by setting the parameters of the problem as extra coordinates: u ≈ u N ( x 1 , … , x d ; k 1 , … , k p ) = ∑ i = 1 N X 1 i ( x 1 ) ⋯ X d i ( x d ) ⋅ K 1 i ( k 1 ) ⋯ K p i ( k p ) , {\displaystyle \mathbf {u} \approx \mathbf {u} ^{N}(x_{1},\ldots ,x_{d};k_{1},\ldots ,k_{p})=\sum _{i=1}^{N}\mathbf {X_{1}} _{i}(x_{1})\cdots \mathbf {X_{d}} _{i}(x_{d})\cdot \mathbf {K_{1}} _{i}(k_{1})\cdots \mathbf {K_{p}} _{i}(k_{p}),} where a series of functional products K1(k1), K2(k2), ..., Kp(kp), each depending on a parameter (or parameters), has been incorporated to the equation. In this case, the obtained approximation of the solution is called computational vademecum: a general meta-model containing all the particular solutions for every possible value of the involved parameters. == Sparse Subspace Learning == The Sparse Subspace Learning (SSL) method leverages the use of hierarchical collocation to approximate the numerical solution of parametric models. With respect to traditional projection-based reduced order modeling, the use of a collocation enables non-intrusive approach based on sparse adaptive sampling of the parametric space. This allows to recover the lowdimensional structure of the parametric solution subspace while also learning the functional dependency from the parameters in explicit form. A sparse low-rank approximate tensor representation of the parametric solution can be built through an incremental strategy that only needs to have access to the output of a deterministic solver. Non-intrusiveness makes this approach straightforwardly applicable to challenging problems characterized by nonlinearity or non affine weak forms.
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Uniphore

Uniphore is an American software company that develops artificial intelligence platforms for business use. The company is headquartered in Palo Alto, California, with offices in the United States, United Kingdom, Spain, Israel, United Arab Emirates, and India. Uniphore is known for its "Business AI Cloud," an enterprise AI platform that combines data, knowledge, models, and software agents for use in sales, marketing, and service. The company has also acquired firms in video emotion AI, AI agents, low-code automation, knowledge automation, voice and screen capture, customer data platforms, and data engineering. == History == Uniphore Software Systems was founded by Umesh Sachdev and Ravi Saraogi in 2008 and was incubated at IIT Madras. The company received an initial grant of $100,000 from the National Research Development Corporation. Early work focused on speech technologies for emerging markets. Uniphore partnered with companies that specialized in English and European languages, and adapting the technology for Indian languages and dialects. In 2014, Uniphore released its first flagship products, auMina, along with two other products, Akeira and amVoice. Uniphore raised series A funding, led by Kris Gopalakrishnan (cofounder of Infosys), in April 2015. The next month, Uniphore received additional investment from IDG Ventures. With input from its investors, Uniphore changed its business model from license fee-based income to a software as a service-based subscription fee model in 2015. By June 2016, it had added more than 70 global languages and expanded its services to Southeast Asia, the Middle East, and the United States. The company opened operations in Singapore in October 2016. The company raised Series B funding in October 2017, led by John Chambers and existing investors. Series C funding of $51 million was announced in August 2019 and led by March Capital. Uniphore acquired an exclusive third-party license for robotic process automation technology from NTT DATA in October 2020. In January 2021, Uniphore acquired Emotion Research Lab, a startup based in Spain that uses artificial intelligence and machine learning to analyze video and interpret emotions. The company received $140 million in Series D funding, led by Sorenson Capital Partners, in March 2021, bringing total funding to $210 million. In January 2021, Uniphore acquired Emotion Research Lab. In July 2021, it agreed to acquire Jacada, a provider of low-code/no-code automation; the transaction closed in October 2021. On February 16, 2022, Uniphore announced a $400 million Series E financing led by NEA, which valued the company at $2.5 billion. Hilarie Koplow-McAdams, an NEA venture partner and former Salesforce/New Relic executive, joined Uniphore's board in 2022. Uniphore's board has also included former Cisco CEO John Chambers, former Convergys CEO Andrea J. Ayers, and CrowdStrike CFO Burt Podbere (appointed January 2021). In February 2023, Uniphore acquired UK-based Red Box, a platform for capturing voice and screen recordings used in regulated and large-scale environments. It also acquired France-based Hexagone, a behavioral analytics firm combining computer vision and natural-language techniques. On December 5, 2024, Uniphore announced agreements to acquire ActionIQ, a customer data platform (CDP) vendor, and Infoworks, an enterprise data engineering platform. Uniphore launched the Business AI Cloud on June 9, 2025. The Business AI Cloud consists of a single, unified platform that includes data, knowledge, AI models, and AI agents. Uniphore announced in August 2025 that it had acquired Orby AI and intended to acquire Autonom8 to extend multi-agent and workflow automation capabilities. As of September 2025, Uniphore's customers included the United States Coast Guard, Singapore Police Force, London Underground, DirecTV, JPMorgan Chase, LG, DHL, UPS, Vodafone, Verizon, NTT Data, and as of May 2021, Firstsource. In October 2025, Uniphore raised $260 million in a Series F round at a reported valuation of $2.5 billion. Investors included March Capital, NEA, Nvidia, AMD, Snowflake, and Databricks. In January 2026, KPMG and Uniphore announced a collaboration focused on deploying AI agents powered by specialized small language models. The announcement was made at the World Economic Forum held in Davos. Cognizant and Uniphore announced a partnership in February 2026 to develop industry-specific AI tools for regulated sectors, which would initially focus on life sciences and finance. Uniphore and Rackspace also announced a partnership in March 2026. This partnership was announced in order to create an "Infrastructure-to-Agents" architecture, focusing on Business AI as a private cloud service. == Products == As of 2025, Uniphore's core offering is the Business AI Cloud and Business AI Suite of agentic AI applications. === Business AI Cloud === Uniphore’s Business AI Cloud is a full-stack platform that organizes enterprise data and knowledge for agentic AI applications. The platform enables deployment across clouds and existing data sources. Key layers and capabilities include the following. Agentic layer: Includes prebuilt agents, a natural-language agent builder, and orchestration based on Business Process Model and Notation (BPMN) to run AI workflows across business units. Model layer: Supports an open, interoperable mix of closed and open-source large language models (LLMs). Models can be orchestrated, governed, and replaced as needed. Knowledge layer: Organizes raw data into structured knowledge used for retrieval, explainability, and fine-tuning of small language models (SLMs). Data layer: Connects to data across multiple platforms and clouds through a zero-copy, composable fabric, enabling in-place preparation and supporting data residency and sovereignty requirements. === Business AI Suite === The Uniphore Business AI Suite has various prebuilt AI agents that can be used in customer service, sales, marketing, and human resources. The Uniphore Business AI Suite includes several LOBs (Lines of Business) for business functions with intelligent agents that are prebuilt, but composable. Built on the Uniphore Business AI Cloud, each application combines agentic automation and fine-tuned models. Marketing AI, Customer Service AI, Sales AI, and People AI (for human resources) are included. Competitors include Palantir, Microsoft Azure, Amazon Bedrock, Google's Vertex AI, Databricks, and Snowflake. == Recognition == Deloitte Technology Fast 50 India identified Uniphore as the 17th fastest-growing technology company in India in 2012 and one of the top 500 fastest growing companies in the Asia-Pacific region in 2014. In 2016, Time included Sachdev on its list of "10 millennials who are changing the world" for “building a phone that can understand almost any language”. NASSCOM named Uniphore to its "League of 10" emerging Indian technology companies in 2017. In 2020, the San Francisco Business Times ranked Uniphore as No. 7 among small companies in its list of the best places to work in the San Francisco Bay Area. In 2022, the company was featured on the Forbes AI 50 list. Uniphore was mentioned in the Deloitte Technology Fast 500 list in 2023, 2024, and 2025. In 2025, Inc. included Uniphore in its Best in Business program.
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Structured kNN

Structured k-nearest neighbours (SkNN) is a machine learning algorithm that generalizes k-nearest neighbors (k-NN). k-NN supports binary classification, multiclass classification, and regression, whereas SkNN allows training of a classifier for general structured output. For instance, a data sample might be a natural language sentence, and the output could be an annotated parse tree. Training a classifier consists of showing many instances of ground truth sample-output pairs. After training, the SkNN model is able to predict the corresponding output for new, unseen sample instances; that is, given a natural language sentence, the classifier can produce the most likely parse tree. == Training == As a training set, SkNN accepts sequences of elements with class labels. The type of element does not matter; the only requirement is a defined metric function that gives a distance between each pair of elements of a set. SkNN is based on idea of creating a graph, with each node representing a class label. There is an edge between a pair of nodes if there is a sequence of two elements in the training set with corresponding classes. The first step of SkNN training is the construction of such a graph from training sequences. There are two special nodes in the graph corresponding to sentence beginnings and ends: if a sequence starts with class C, the edge between node START and node C should be created. Like regular k-NN, the second part of SkNN training consists of storing the elements of a training sequence in a certain way. Each element of the training sequences is stored in the node related to the class of the previous element in the sequence. Every first element is stored in the START node. == Inference == Labelling input sequences by SkNN consists of finding the sequence of transitions in the graph, starting from node START. Each transition corresponds to a single element of the input sequence. As a result, the label of each element is determined as the target node label of the transition. The cost of the path is defined as the sum of all transitions, with the cost of transition from node A to node B being the distance from the current input sequence element to the nearest element of class B, stored in node A. Determining an optimal path may be performed using a modified Viterbi algorithm (where the sum of the distances is minimized, unlike the original algorithm which maximizes the product of probabilities).
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KXEN Inc.

KXEN was an American software company which existed from 1998 to 2013 when it was acquired by SAP AG. == History == KXEN was founded in June 1998 by Roger Haddad and Michel Bera. It was based in San Francisco, California with offices in Paris and London. On September 10, 2013, SAP AG announced plans to acquire KXEN. On October 1, 2013, a letter to KXEN customers announced the acquisition closed. KXEN primarily marketed predictive analytics software. == Predictive analytics == InfiniteInsight is a predictive modeling suite developed by KXEN that assists analytic professionals, and business executives to extract information from data. Among other functions, InfiniteInsight is used for variable importance, classification, regression, segmentation, time series, product recommendation, as described and expressed by the Java Data Mining interface, and for social network analysis. InfiniteInsight allows prediction of a behavior or a value, the forecast of a time series or the understanding of a group of individuals with similar behavior. Advanced functions include behavioral modeling, exporting the model code into different target environments or building predictive models on top of SAS or SPSS data files. Competitors are SAS Enterprise Miner, IBM SPSS Modeler, and Statistica. Open source predictive tools like the R package or Weka are also competitors, since they provide similar features free of charge.
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