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  Biopython

  Biopython is an open-source collection of non-commercial Python modules for computational biology and bioinformatics. It makes robust and well-tested code easily accessible to researchers. Python is an object-oriented programming language and is a suitable choice for automation of common tasks. The availability of reusable libraries saves development time and lets researchers focus on addressing scientific questions. Biopython is constantly updated and maintained by a large team of volunteers across the globe. Biopython contains parsers for diverse bioinformatic sequence, alignment, and structure formats. Sequence formats include FASTA, FASTQ, GenBank, and EMBL. Alignment formats include Clustal, BLAST, PHYLIP, and NEXUS. Structural formats include the PDB, which contains the 3D atomic coordinates of the macromolecules. It has provisions to access information from biological databases like NCBI, Expasy, PBD, and BioSQL. This can be used in scripts or incorporated into their software. Biopython contains a standard sequence class, sequence alignment, and motif analysis tools. It also has clustering algorithms, a module for structural biology, and a module for phylogenetics analysis. == History == The development of Biopython began in 1999, and it was first released in July 2000. First "semi-complete" and "semi-stable" release was done in March 2001 and December 2002 respectively. It was developed during a similar time frame and with analogous goals to other projects that added bioinformatics capabilities to their respective programming languages, including BioPerl, BioRuby and BioJava. Early developers on the project included Jeff Chang, Andrew Dalke and Brad Chapman, though over 100 people have made contributions to date. In 2007, a similar Python project, namely PyCogent, was established. The initial scope of Biopython involved accessing, indexing and processing biological sequence files. The retrieved data from common biological databases will then be parsed into a python data structure. While this is still a major focus, over the following years added modules have extended its functionality to cover additional areas of biology. The key challenge in the design of parsers for bioinformatics file formats is the frequency at which the data formats change. This is due to inadequate curation of the structure of the data, and changes in the database contents. This problem is overcome by the application of a standard event-oriented parser design (see Key features and examples). As of version 1.77, Biopython no longer supports Python 2. The current stable release of Biopython version 1.85 was released on 15 January 2025. It only supports Python 3 and the recent releases of Biopython require NumPy (and not Numeric). == Design == Wherever possible, Biopython follows the conventions used by the Python programming language to make it easier for users familiar with Python. For example, Seq and SeqRecord objects can be manipulated via slicing, in a manner similar to Python's strings and lists. It is also designed to be functionally similar to other Bio projects, such as BioPerl. It is organized into modular sub-packages, e.g., Bio.Seq, Bio.Align, Bio.PDB, Bio.Entrez each of them useful in a different bioinformatics domain. It used principles, like encapsulation and polymorphism, notably in classes Seq, SeqRecord, and Bio.PDB.Structure. It can also interoperate with other Python tools (Pandas, Matplotlib and SciPy). Biopython can read and write most common file formats for each of its functional areas, and its license is permissive and compatible with most other software licenses, which allows Biopython to be used in a variety of software projects. == Requirements == Biopython is currently supported and tested with the following Python implementations: Python 3 or PyPy3 NumPy == Key features and examples == === Input and output === Biopython can read and write to a number of common formats. When reading files, descriptive information in the file is used to populate the members of Biopython classes, such as SeqRecord. This allows records of one file format to be converted into others. Very large sequence files can exceed a computer's memory resources, so Biopython provides various options for accessing records in large files. They can be loaded entirely into memory in Python data structures, such as lists or dictionaries, providing fast access at the cost of memory usage. Alternatively, the files can be read from disk as needed, with slower performance but lower memory requirements. === Sequences === A core concept in Biopython is the biological sequence, and this is represented by the Seq class. A Biopython Seq object is similar to a Python string in many respects: it supports the Python slice notation, can be concatenated with other sequences and is immutable. This object includes both general string-like and biological sequence-specific methods. It is best to store information about the biological type (DNA, RNA, protein) separately from the sequence, rather than using an explicit alphabet argument. === Sequence annotation === The SeqRecord class describes sequences, along with information such as name, description and features in the form of SeqFeature objects. Each SeqFeature object specifies the type of the feature and its location. Feature types can be ‘gene’, ‘CDS’ (coding sequence), ‘repeat_region’, ‘mobile_element’ or others, and the position of features in the sequence can be exact or approximate. === Accessing online databases === Through the Bio.Entrez module, users of Biopython can download biological data from NCBI databases. Each of the functions provided by the Entrez search engine is available through functions in this module, including searching for and downloading records. === Phylogeny === The Bio.Phylo module provides tools for working with and visualising phylogenetic trees. A variety of file formats are supported for reading and writing, including Newick, NEXUS and phyloXML. Common tree manipulations and traversals are supported via the Tree and Clade objects. Examples include converting and collating tree files, extracting subsets from a tree, changing a tree's root, and analysing branch features such as length or score. Rooted trees can be drawn in ASCII or using matplotlib (see Figure 1), and the Graphviz library can be used to create unrooted layouts (see Figure 2). === Genome diagrams === The GenomeDiagram module provides methods of visualising sequences within Biopython. Sequences can be drawn in a linear or circular form (see Figure 3), and many output formats are supported, including PDF and PNG. Diagrams are created by making tracks and then adding sequence features to those tracks. By looping over a sequence's features and using their attributes to decide if and how they are added to the diagram's tracks, one can exercise much control over the appearance of the final diagram. Cross-links can be drawn between different tracks, allowing one to compare multiple sequences in a single diagram. === Macromolecular structure === The Bio.PDB module can load molecular structures from PDB and mmCIF files, and was added to Biopython in 2003. The Structure object is central to this module, and it organises macromolecular structure in a hierarchical fashion: Structure objects contain Model objects which contain Chain objects which contain Residue objects which contain Atom objects. Disordered residues and atoms get their own classes, DisorderedResidue and DisorderedAtom, that describe their uncertain positions. Using Bio.PDB, one can navigate through individual components of a macromolecular structure file, such as examining each atom in a protein. Common analyses can be carried out, such as measuring distances or angles, comparing residues and calculating residue depth. === Population genetics === The Bio.PopGen module adds support to Biopython for Genepop, a software package for statistical analysis of population genetics. This allows for analyses of Hardy–Weinberg equilibrium, linkage disequilibrium and other features of a population's allele frequencies. This module can also carry out population genetic simulations using coalescent theory with the fastsimcoal2 program. === Wrappers for command line tools === Biopython previously included command-line wrappers for tools such as BLAST, Clustal, EMBOSS, and SAMtools. This option allowed users to run external tool commands from within the code using specialized Biopython classes. However, Bio.Application modules and their wrappers have deprecated and will be removed in future Biopython releases. The main reason for this is the high maintenance burden of updating them with the evolving external tools. The recommended approach is to directly construct and execute command-line tool commands using Python’s built-in subprocess module. This method provides flexibility and removes the dependency on the Biopython wrappers. subprocess is a native Python module useful for running ext

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  Aporia (company)

  Aporia is a machine learning observability platform based in Tel Aviv, Israel. The company has a US office located in San Jose, California. Aporia has developed software for monitoring and controlling undetected defects and failures used by other companies to detect and report anomalies, and warn in the early stages of faults. == History == Aporia was founded in 2019 by Liran Hason and Alon Gubkin. In April 2021, the company raised a $5 million seed round for its monitoring platform for ML models. In February 2022, the company closed a Series A round of $25 million for its ML observability platform. Aporia was named by Forbes as the Next Billion-Dollar Company in June 2022. In November, the company partnered with ClearML, an MLOPs platform, to improve ML pipeline optimization. In January 2023, Aporia launched Direct Data Connectors, a novel technology allowing organizations to monitor their ML models in minutes (previously the process of integrating ML monitoring into a customer’s cloud environment took weeks or more.) DDC (Direct Data Connectors) enables users to connect Aporia to their preferred data source and monitor all of their data at once, without data sampling or data duplication (which is a huge security risk for major organizations. In April 2023, Aporia announced the company partnered with Amazon Web Services (AWS) to provide more reliable ML observability to AWS consumers by deploying Aporia's architecture to their AWS environment, this will allow customers to monitor their models in production regardless of platform.

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  Inception score

  The Inception Score (IS) is an algorithm used to assess the quality of images created by a generative image model such as a generative adversarial network (GAN). The score is calculated based on the output of a separate, pretrained Inception v3 image classification model applied to a sample of (typically around 30,000) images generated by the generative model. The Inception Score is maximized when the following conditions are true: The entropy of the distribution of labels predicted by the Inceptionv3 model for the generated images is minimized. In other words, the classification model confidently predicts a single label for each image. Intuitively, this corresponds to the desideratum of generated images being "sharp" or "distinct". The predictions of the classification model are evenly distributed across all possible labels. This corresponds to the desideratum that the output of the generative model is "diverse". It has been somewhat superseded by the related Fréchet inception distance. While the Inception Score only evaluates the distribution of generated images, the FID compares the distribution of generated images with the distribution of a set of real images ("ground truth"). == Definition == Let there be two spaces, the space of images Ω X {\displaystyle \Omega _{X}} and the space of labels Ω Y {\displaystyle \Omega _{Y}} . The space of labels is finite. Let p g e n {\displaystyle p_{gen}} be a probability distribution over Ω X {\displaystyle \Omega _{X}} that we wish to judge. Let a discriminator be a function of type p d i s : Ω X → M ( Ω Y ) {\displaystyle p_{dis}:\Omega _{X}\to M(\Omega _{Y})} where M ( Ω Y ) {\displaystyle M(\Omega _{Y})} is the set of all probability distributions on Ω Y {\displaystyle \Omega _{Y}} . For any image x {\displaystyle x} , and any label y {\displaystyle y} , let p d i s ( y | x ) {\displaystyle p_{dis}(y|x)} be the probability that image x {\displaystyle x} has label y {\displaystyle y} , according to the discriminator. It is usually implemented as an Inception-v3 network trained on ImageNet. The Inception Score of p g e n {\displaystyle p_{gen}} relative to p d i s {\displaystyle p_{dis}} is I S ( p g e n , p d i s ) := exp ⁡ ( E x ∼ p g e n [ D K L ( p d i s ( ⋅ | x ) ‖ ∫ p d i s ( ⋅ | x ) p g e n ( x ) d x ) ] ) {\displaystyle IS(p_{gen},p_{dis}):=\exp \left(\mathbb {E} _{x\sim p_{gen}}\left[D_{KL}\left(p_{dis}(\cdot |x)\|\int p_{dis}(\cdot |x)p_{gen}(x)dx\right)\right]\right)} Equivalent rewrites include ln ⁡ I S ( p g e n , p d i s ) := E x ∼ p g e n [ D K L ( p d i s ( ⋅ | x ) ‖ E x ∼ p g e n [ p d i s ( ⋅ | x ) ] ) ] {\displaystyle \ln IS(p_{gen},p_{dis}):=\mathbb {E} _{x\sim p_{gen}}\left[D_{KL}\left(p_{dis}(\cdot |x)\|\mathbb {E} _{x\sim p_{gen}}[p_{dis}(\cdot |x)]\right)\right]} ln ⁡ I S ( p g e n , p d i s ) := H [ E x ∼ p g e n [ p d i s ( ⋅ | x ) ] ] − E x ∼ p g e n [ H [ p d i s ( ⋅ | x ) ] ] {\displaystyle \ln IS(p_{gen},p_{dis}):=H[\mathbb {E} _{x\sim p_{gen}}[p_{dis}(\cdot |x)]]-\mathbb {E} _{x\sim p_{gen}}[H[p_{dis}(\cdot |x)]]} ln ⁡ I S {\displaystyle \ln IS} is nonnegative by Jensen's inequality. Pseudocode:INPUT discriminator p d i s {\displaystyle p_{dis}} . INPUT generator g {\displaystyle g} . Sample images x i {\displaystyle x_{i}} from generator. Compute p d i s ( ⋅ | x i ) {\displaystyle p_{dis}(\cdot |x_{i})} , the probability distribution over labels conditional on image x i {\displaystyle x_{i}} . Sum up the results to obtain p ^ {\displaystyle {\hat {p}}} , an empirical estimate of ∫ p d i s ( ⋅ | x ) p g e n ( x ) d x {\displaystyle \int p_{dis}(\cdot |x)p_{gen}(x)dx} . Sample more images x i {\displaystyle x_{i}} from generator, and for each, compute D K L ( p d i s ( ⋅ | x i ) ‖ p ^ ) {\displaystyle D_{KL}\left(p_{dis}(\cdot |x_{i})\|{\hat {p}}\right)} . Average the results, and take its exponential. RETURN the result. === Interpretation === A higher inception score is interpreted as "better", as it means that p g e n {\displaystyle p_{gen}} is a "sharp and distinct" collection of pictures. ln ⁡ I S ( p g e n , p d i s ) ∈ [ 0 , ln ⁡ N ] {\displaystyle \ln IS(p_{gen},p_{dis})\in [0,\ln N]} , where N {\displaystyle N} is the total number of possible labels. ln ⁡ I S ( p g e n , p d i s ) = 0 {\displaystyle \ln IS(p_{gen},p_{dis})=0} iff for almost all x ∼ p g e n {\displaystyle x\sim p_{gen}} p d i s ( ⋅ | x ) = ∫ p d i s ( ⋅ | x ) p g e n ( x ) d x {\displaystyle p_{dis}(\cdot |x)=\int p_{dis}(\cdot |x)p_{gen}(x)dx} That means p g e n {\displaystyle p_{gen}} is completely "indistinct". That is, for any image x {\displaystyle x} sampled from p g e n {\displaystyle p_{gen}} , discriminator returns exactly the same label predictions p d i s ( ⋅ | x ) {\displaystyle p_{dis}(\cdot |x)} . The highest inception score N {\displaystyle N} is achieved if and only if the two conditions are both true: For almost all x ∼ p g e n {\displaystyle x\sim p_{gen}} , the distribution p d i s ( y | x ) {\displaystyle p_{dis}(y|x)} is concentrated on one label. That is, H y [ p d i s ( y | x ) ] = 0 {\displaystyle H_{y}[p_{dis}(y|x)]=0} . That is, every image sampled from p g e n {\displaystyle p_{gen}} is exactly classified by the discriminator. For every label y {\displaystyle y} , the proportion of generated images labelled as y {\displaystyle y} is exactly E x ∼ p g e n [ p d i s ( y | x ) ] = 1 N {\displaystyle \mathbb {E} _{x\sim p_{gen}}[p_{dis}(y|x)]={\frac {1}{N}}} . That is, the generated images are equally distributed over all labels.

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  Moral outsourcing

  Moral outsourcing is the placing of responsibility for ethical decision-making onto external entities, often algorithms. The term is often used in discussions of computer science and algorithmic fairness, but it can apply to any situation in which one appeals to outside agents in order to absolve themselves of responsibility for their actions. In this context, moral outsourcing specifically refers to the tendency of society to blame technology, rather than its creators or users, for any harm it may cause. == Definition == The term "moral outsourcing" was first coined by Dr. Rumman Chowdhury, a data scientist concerned with the overlap between artificial intelligence and social issues. Chowdhury used the term to describe looming fears of a so-called “Fourth Industrial Revolution” following the rise of artificial intelligence. Moral outsourcing is often applied by technologists to shrink away from their part in building offensive products. In her TED Talk, Chowdhury gives the example of a creator excusing their work by saying they were simply doing their job. This is a case of moral outsourcing and not taking ownership for the consequences of creation. When it comes to AI, moral outsourcing allows for creators to decide when the machine is human and when it is a computer - shifting the blame and responsibility of moral plights off of the technologists and onto the technology. Conversations around AI and bias and its impacts require accountability to bring change. It is difficult to address these biased systems if their creators use moral outsourcing to avoid taking any responsibility for the issue. One example of moral outsourcing is the anger that is directed at machines for “taking jobs away from humans” rather than companies for employing that technology and jeopardizing jobs in the first place. The term "moral outsourcing" refers to the concept of outsourcing, or enlisting an external operation to complete specific work for another organization. In the case of moral outsourcing, the work of resolving moral dilemmas or making choices according to an ethical code is supposed to be conducted by another entity. == Real-world applications == In the medical field, AI is increasingly involved in decision-making processes about which patients to treat, and how to treat them. The responsibility of the doctor to make informed decisions about what is best for their patients is outsourced to an algorithm. Sympathy is also noted to be an important part of medical practice; an aspect that artificial intelligence, glaringly, is missing. This form of moral outsourcing is a major concern in the medical community. Another field of technology in which moral outsourcing is frequently brought up is autonomous vehicles. California Polytechnic State University professor Keith Abney proposed an example scenario: "Suppose we have some [troublemaking] teenagers, and they see an autonomous vehicle, they drive right at it. They know the autonomous vehicle will swerve off the road and go off a cliff, but should it?" The decision of whether to sacrifice the autonomous vehicle (and any passengers inside) or the vehicle coming at it will be written into the algorithms defining the car's behavior. In the case of moral outsourcing, the responsibility of any damage caused by an accident may be attributed to the autonomous vehicle itself, rather than the creators who wrote the protocol the vehicle will use to "decide" what to do. Moral outsourcing is also used to delegate the consequences of predictive policing algorithms to technology, rather than the creators or the police. There are many ethical concerns with predictive policing due to the fact that it results in the over-policing of low income and minority communities. In the context of moral outsourcing, the positive feedback loop of sending disproportionate police forces into minority communities is attributed to the algorithm and the data being fed into this system--rather than the users and creators of the predictive policing technology. == Outside of technology == === Religion === Moral outsourcing is also commonly seen in appeals to religion to justify discrimination or harm. In his book What It Means to be Moral, sociologist Phil Zuckerman contradicts the popular religious notion that morality comes from God. Religion is oftentimes cited as a foundation for a moral stance without any tangible relation between the religious beliefs and personal stance. In these cases, religious individuals will "outsource" their personal beliefs and opinions by claiming that they are a result of their religious identification. This is seen where religion is cited as a factor for political beliefs, medical beliefs, and in extreme cases an excuse for violence. === Manufacturing === Moral outsourcing can also be seen in the business world in terms of manufacturing goods and avoiding environmental responsibility. Some companies in the United States will move their production process to foreign countries with more relaxed environmental policies to avoid the pollution laws that exist in the US. A study by the Harvard Business Review found that "in countries with tight environmental regulation, companies have 29% lower domestic emissions on average. On the other hand, such a tightening in regulation results in 43% higher emissions abroad." The consequences of higher pollution rates are then attributed to the loose regulations in these countries, rather than on the companies themselves who purposefully moved into these areas to avoid strict pollution policy.

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  Pixel aspect ratio

  A pixel aspect ratio (PAR) is a mathematical ratio that describes how the width of a pixel in a digital image compares to the height of that pixel. Most digital imaging systems display an image as a grid of tiny, square pixels. However, some imaging systems, especially those that must be compatible with standard-definition television motion pictures, display an image as a grid of rectangular pixels, in which the pixel width and height are different. Pixel aspect ratio describes this difference. Use of pixel aspect ratio mostly involves pictures pertaining to standard-definition television and some other exceptional cases. Most other imaging systems, including those that comply with SMPTE standards and practices, use square pixels. PAR is also known as sample aspect ratio and abbreviated SAR, though it can be confused with storage aspect ratio. == Introduction == The ratio of the width to the height of an image is known as the aspect ratio, or more precisely the display aspect ratio (DAR) – the aspect ratio of the image as displayed; for TV, DAR was traditionally 4:3 (a.k.a. fullscreen), with 16:9 (a.k.a. widescreen) now the standard for HDTV. In digital images, there is a distinction with the storage aspect ratio (SAR), which is the ratio of pixel dimensions. If an image is displayed with square pixels, then these ratios agree; if not, then non-square, "rectangular" pixels are used, and these ratios disagree. The aspect ratio of the pixels themselves is known as the pixel aspect ratio (PAR) – for square pixels this is 1:1 – and these are related by the identity: Rearranging (solving for PAR) yields: For example: A 640 × 480 VGA image has a SAR of 640/480 = 4:3, and if displayed on a 4:3 display (DAR = 4:3) has square pixels, hence a PAR of 1:1. By contrast, a 720 × 576 D-1 PAL image has a SAR of 720/576 = 5:4, but if displayed on a 4:3 display (DAR = 4:3) the PAR is 4/3 : 5/4 = 16:15 ≈ 1.066. This means that the pixels of the PAL picture must be "stretched" by this amount to fit in the 4:3 display. In analog images such as film there is no notion of pixel, nor notion of SAR or PAR, but in the digitization of analog images the resulting digital image has pixels, hence SAR (and accordingly PAR, if displayed at the same aspect ratio as the original). Non-square pixels arise often in early digital TV standards, related to digitalization of analog TV signals – whose vertical and "effective" horizontal resolutions differ and are thus best described by non-square pixels – and also in some digital video cameras and computer display modes, such as Color Graphics Adapter (CGA). Today they arise also in transcoding between resolutions with different SARs. Actual displays do not generally have non-square pixels, though digital sensors might; they are rather a mathematical abstraction used in resampling images to convert between resolutions. There are several complicating factors in understanding PAR, particularly as it pertains to digitization of analog video: First, analog video does not have pixels, but rather a raster scan, and thus has a well-defined vertical resolution (the lines of the raster), but not a well-defined horizontal resolution, since each line is an analog signal. However, by a standardized sampling rate, the effective horizontal resolution can be determined by the sampling theorem, as is done below. Second, due to overscan, some of the lines at the top and bottom of the raster are not visible, as are some of the possible image on the left and right – see Overscan: Analog to digital resolution issues. Also, the resolution may be rounded (DV NTSC uses 480 lines, rather than the 486 that are possible). Third, analog video signals are interlaced – each image (frame) is sent as two "fields", each with half the lines. Thus either the pixels are twice as tall as they would be without interlacing, or the image is deinterlaced. == Background == Video is presented as a sequential series of images called video frames. Historically, video frames were created and recorded in analog form. As digital display technology, digital broadcast technology, and digital video compression evolved separately, it resulted in video frame differences that must be addressed using pixel aspect ratio. Digital video frames are generally defined as a grid of pixels used to present each sequential image. The horizontal component is defined by pixels (or samples), and is known as a video line. The vertical component is defined by the number of lines, as in 480 lines. Standard-definition television standards and practices were developed as broadcast technologies and intended for terrestrial broadcasting, and were therefore not designed for digital video presentation. Such standards define an image as an array of well-defined horizontal "Lines", well-defined vertical "Line Duration" and a well-defined picture center. However, there is not a standard-definition television standard that properly defines image edges or explicitly demands a certain number of picture elements per line. Furthermore, analog video systems such as NTSC 480i and PAL 576i, instead of employing progressively displayed frames, employ fields or interlaced half-frames displayed in an interwoven manner to reduce flicker and double the image rate for smoother motion. === Analog-to-digital conversion === As a result of computers becoming powerful enough to serve as video editing tools, video digital-to-analog converters and analog-to-digital converters were made to overcome this incompatibility. To convert analog video lines into a series of square pixels, the industry adopted a default sampling rate at which luma values were extracted into pixels. The luma sampling rate for 480i pictures was 12+3⁄11 MHz and for 576i pictures was 14+3⁄4 MHz. The term pixel aspect ratio was first coined when ITU-R BT.601 (commonly known as Rec. 601) specified that standard-definition television pictures are made of lines of exactly 720 non-square pixels. ITU-R BT.601 did not define the exact pixel aspect ratio but did provide enough information to calculate the exact pixel aspect ratio based on industry practices: The standard luma sampling rate of precisely 13+1⁄2 MHz. Based on this information: The pixel aspect ratio for 480i would be 10:11 as: 12 3 11 ÷ 13 1 2 = 10 11 {\displaystyle 12{\tfrac {3}{11}}\div 13{\tfrac {1}{2}}={\tfrac {10}{11}}} The pixel aspect ratio for 576i would be 59:54 as: 14 3 4 ÷ 13 1 2 = 59 54 {\displaystyle 14{\tfrac {3}{4}}\div 13{\tfrac {1}{2}}={\tfrac {59}{54}}} SMPTE RP 187 further attempted to standardize the pixel aspect ratio values for 480i and 576i. It designated 177:160 for 480i or 1035:1132 for 576i. However, due to significant difference with practices in effect by industry and the computational load that they imposed upon the involved hardware, SMPTE RP 187 was simply ignored. SMPTE RP 187 information annex A.4 further suggested the use of 10:11 for 480i. As of this writing, ITU-R BT.601-6, which is the latest edition of ITU-R BT.601, still implies that the pixel aspect ratios mentioned above are correct. === Digital video processing === As stated above, ITU-R BT.601 specified that standard-definition television pictures are made of lines of 720 non-square pixels, sampled with a precisely specified sampling rate. A simple mathematical calculation reveals that a 704 pixel width would be enough to contain a 480i or 576i standard 4:3 picture: A 4:3 480-line picture, digitized with the Rec. 601-recommended sampling rate, would be 704 non-square pixels wide. x 480 × 10 11 = 4 3 ⇒ x = 480 × 11 × 4 10 × 3 = 704 {\displaystyle {\frac {x}{480}}\times {\frac {10}{11}}={\frac {4}{3}}\Rightarrow x={\frac {480\times 11\times 4}{10\times 3}}=704} A 4:3 576-line picture, digitized with the Rec. 601-recommended sampling rate, would be 702+54⁄59 non-square pixels wide. x 576 × 59 54 = 4 3 ⇒ x = 576 × 54 × 4 59 × 3 = 702 54 59 {\displaystyle {\frac {x}{576}}\times {\frac {59}{54}}={\frac {4}{3}}\Rightarrow x={\frac {576\times 54\times 4}{59\times 3}}=702{\tfrac {54}{59}}} Unfortunately, not all standard TV pictures are exactly 4:3: As mentioned earlier, in analog video, the center of a picture is well-defined but the edges of the picture are not standardized. As a result, some analog devices (mostly PAL devices but also some NTSC devices) generated motion pictures that were horizontally (slightly) wider. This also proportionately applies to anamorphic widescreen (16:9) pictures. Therefore, to maintain a safe margin of error, ITU-R BT.601 required sampling 16 more non-square pixels per line (8 more at each edge) to ensure saving all video data near the margins. This requirement, however, had implications for PAL motion pictures. PAL pixel aspect ratios for standard (4:3) and anamorphic wide screen (16:9), respectively 59:54 and 118:81, were awkward for digital image processing, especially for mixing PAL and NTSC video clips. Therefore, video editing products chose the almost equivalent value

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  Quantum artificial life

  Quantum artificial life is the application of quantum algorithms with the ability to simulate biological behavior. Quantum computers offer many potential improvements to processes performed on classical computers, including machine learning and artificial intelligence. Artificial intelligence applications are often inspired by the idea of mimicking human brains through closely related biomimicry. This has been implemented to a certain extent on classical computers (using neural networks), but quantum computers offer many advantages in the simulation of artificial life. Artificial life and artificial intelligence are extremely similar, with minor differences; the goal of studying artificial life is to understand living beings better, while the goal of artificial intelligence is to create intelligent beings. In 2016, Alvarez-Rodriguez et al. developed a proposal for a quantum artificial life algorithm with the ability to simulate life and Darwinian evolution. In 2018, the same research team led by Alvarez-Rodriguez performed the proposed algorithm on the IBM ibmqx4 quantum computer, and received optimistic results. The results accurately simulated a system with the ability to undergo self-replication at the quantum scale. == Artificial life on quantum computers == The growing advancement of quantum computers has led researchers to develop quantum algorithms for simulating life processes. Researchers have designed a quantum algorithm that can accurately simulate Darwinian Evolution. Since the complete simulation of artificial life on quantum computers has only been actualized by one group, this section shall focus on the implementation by Alvarez-Rodriguez, Sanz, Lomata, and Solano on an IBM quantum computer. Individuals were realized as two qubits, one representing the genotype of the individual and the other representing the phenotype. The genotype is copied to transmit genetic information through generations, and the phenotype is dependent on the genetic information as well as the individual's interactions with their environment. In order to set up the system, the state of the genotype is instantiated by some rotation of an ancillary state ( | 0 ⟩ ⟨ 0 | {\displaystyle |0\rangle \langle 0|} ). The environment is a two-dimensional spatial grid occupied by individuals and ancillary states. The environment is divided into cells that are able to possess one or more individuals. Individuals move throughout the grid and occupy cells randomly; when two or more individuals occupy the same cell they interact with each other. === Self replication === The ability to self-replicate is critical for simulating life. Self-replication occurs when the genotype of an individual interacts with an ancillary state, creating a genotype for a new individual; this genotype interacts with a different ancillary state in order to create the phenotype. During this interaction, one would like to copy some information about the initial state into the ancillary state, but by the no cloning theorem, it is impossible to copy an arbitrary unknown quantum state. However, physicists have derived different methods for quantum cloning which does not require the exact copying of an unknown state. The method that has been implemented by Alvarez-Rodriguez et al. is one that involves the cloning of the expectation value of some observable. For a unitary U {\displaystyle U} which copies the expectation value of some set of observables X {\displaystyle {\mathsf {X}}} of state ρ {\displaystyle \rho } into a blank state ρ e {\displaystyle \rho _{e}} , the cloning machine is defined by any ( U , ρ e , X ) {\displaystyle (U,\rho _{e},{\mathsf {X}})} that fulfill the following: ∀ ρ ∀ X ∈ X {\displaystyle \forall \rho \forall X\in {\mathsf {X}}} X ¯ = X 1 ¯ = X 2 ¯ {\displaystyle {\bar {X}}={\bar {X_{1}}}={\bar {X_{2}}}} Where X ¯ {\displaystyle {\bar {X}}} is the mean value of the observable in ρ {\displaystyle \rho } before cloning, X 1 ¯ {\displaystyle {\bar {X_{1}}}} is the mean value of the observable in ρ {\displaystyle \rho } after cloning, and X 2 ¯ {\displaystyle {\bar {X_{2}}}} is the mean value of the observable in ρ e {\displaystyle \rho _{e}} after cloning. Note that the cloning machine has no dependence on ρ {\displaystyle \rho } because we want to be able to clone the expectation of the observables for any initial state. It is important to note that cloning the mean value of the observable transmits more information than is allowed classically. The calculation of the mean value is defined naturally as: X ¯ = T r [ ρ X ] {\displaystyle {\bar {X}}=Tr[\rho X]} , X 1 ¯ = T r [ R X ⊗ I ] {\displaystyle {\bar {X_{1}}}=Tr[RX\otimes I]} , X 2 ¯ = T r [ R I ⊗ X ] {\displaystyle {\bar {X_{2}}}=Tr[RI\otimes X]} where R = U ρ ⊗ ρ e U † {\displaystyle R=U\rho \otimes \rho _{e}U^{\dagger }} The simplest cloning machine clones the expectation value of σ z {\displaystyle \sigma _{z}} in arbitrary state ρ = | ψ ⟩ ⟨ ψ | {\displaystyle \rho =|\psi \rangle \langle \psi |} to ρ e = | 0 ⟩ ⟨ 0 | {\displaystyle \rho _{e}=|0\rangle \langle 0|} using U = C N O T {\displaystyle U=CNOT} . This is the cloning machine implemented for self-replication by Alvarez-Rodriguez et al. The self-replication process clearly only requires interactions between two qubits, and therefore this cloning machine is the only one necessary for self replication. === Interactions === Interactions occur between individuals when the two take up the same space on the environmental grid. The presence of interactions between individuals provides an advantage for shorter-lifespan individuals. When two individuals interact, exchanges of information between the two phenotypes may or may not occur based on their existing values. When both individual's control qubits (genotypes) are alike, no information will be exchanged. When the control qubits differ, the target qubits (phenotype) will be exchanged between the two individuals. This procedure produces a constantly changing predator-prey dynamic in the simulation. Therefore, long-living qubits, with a larger genetic makeup in the simulation, are at a disadvantage. Since information is only exchanged when interacting with an individual of different genetic makeup, the short-lived population has the advantage. === Mutation === Mutations exist in the artificial world with limited probability, equivalent to their occurrence in the real world. There are two ways in which the individual can mutate: through random single qubit rotations and by errors in the self-replication process. There are two different operators that act on the individual and cause mutations. The M operation causes a spontaneous mutation within the individual by rotating a single qubit by parameter θ. The parameter θ is random for each mutation, which creates biodiversity within the artificial environment. The M operation is a unitary matrix which can be described as: M = ( cos ⁡ ( θ ) s i n ( θ ) s i n ( θ ) − c o s ( θ ) ) {\displaystyle M={\begin{pmatrix}\cos(\theta )&sin(\theta )\\sin(\theta )&-cos(\theta )\end{pmatrix}}} The other possible way for mutations to occur is due to errors in the replication process. Due to the no-cloning theorem, it is impossible to produce perfect copies of systems that are originally in unknown quantum states. However, quantum cloning machines make it possible to create imperfect copies of quantum states, in other words, the process introduces some degree of error. The error that exists in current quantum cloning machines is the root cause for the second kind of mutations in the artificial life experiment. The imperfect cloning operation can be seen as: U M ( θ ) = I 4 + 1 2 ( 0 0 0 1 ) ⊗ ( − 1 1 1 − 1 ) ( c o s θ + i s i n θ + 1 ) {\displaystyle U_{M}(\theta )=\mathrm {I} _{4}+{\frac {1}{2}}{\begin{pmatrix}0&0\\0&1\end{pmatrix}}\otimes {\begin{pmatrix}-1&1\\1&-1\end{pmatrix}}(cos\theta +isin\theta +1)} The two kinds of mutations affect the individual differently. While the spontaneous M operation does not affect the phenotype of the individual, the self-replicating error mutation, UM, alters both the genotype of the individual, and its associated lifetime. The presence of mutations in the quantum artificial life experiment is critical for providing randomness and biodiversity. The inclusion of mutations helps to increase the accuracy of the quantum algorithm. === Death === At the instant the individual is created (when the genotype is copied into the phenotype), the phenotype interacts with the environment. As time evolves, the interaction of the individual with the environment simulates aging which eventually leads to the death of the individual. The death of an individual occurs when the expectation value of σ z {\displaystyle \sigma _{z}} is within some ϵ {\displaystyle \epsilon } of 1 in the phenotype, or, equivalently, when ρ p = | 0 ⟩ ⟨ 0 | {\displaystyle \rho _{p}=|0\rangle \langle 0|} The Lindbladian describes the interaction of the individual with the environment: ρ

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  DABUS

  DABUS (Device for the Autonomous Bootstrapping of Unified Sentience) is an artificial intelligence (AI) system created by Stephen Thaler. It reportedly conceived of two novel products — a food container constructed using fractal geometry, which enables rapid reheating, and a flashing beacon for attracting attention in an emergency. The filing of patent applications designating DABUS as inventor has led to decisions by patent offices and courts on whether a patent can be granted for an invention reportedly made by an AI system. == History in different jurisdictions == === Australia === On 17 September 2019, Thaler filed an application to patent a "Food container and devices and methods for attracting enhanced attention," naming DABUS as the inventor. On 21 September 2020, IP Australia found that section 15(1) of the Patents Act 1990 (Cth) is inconsistent with an artificial intelligence machine being treated as an inventor, and Thaler's application had lapsed. Thaler sought judicial review, and on 30 July 2021, the Federal Court set aside IP Australia's decision and ordered IP Australia to reconsider the application. On 13 April 2022, the Full Court of the Federal Court set aside that decision, holding that only a natural person can be an inventor for the purposes of the Patents Act 1990 (Cth) and the Patents Regulations 1991 (Cth), and that such an inventor must be identified for any person to be entitled to a grant of a patent. On 11 November 2022, Thaler was refused special leave to appeal to the High Court. === European Patent Office === On 17 October 2018 and 7 November 2018, Thaler filed two European patent applications with the European Patent Office. The first claimed invention was a "Food Container" and the second was "Devices and Methods for Attracting Enhanced Attention." On 27 January 2020, the EPO rejected the applications on the grounds that the application listed an AI system named DABUS, and not a human, as the inventor, based on Article 81 and Rule 19(1) of the European Patent Convention (EPC). On 21 December 2021, the Board of Appeal of the EPO dismissed Thaler's appeal from the EPO's primary decision. The Board of Appeal confirmed that "under the EPC the designated inventor has to be a person with legal capacity. This is not merely an assumption on which the EPC was drafted. It is the ordinary meaning of the term inventor." === United Kingdom === Similar applications were filed by Thaler to the United Kingdom Intellectual Property Office on 17 October and 7 November 2018. The Office asked Thaler to file statements of inventorship and of right of grant to a patent (Patent Form 7) in respect of each invention within 16 months of the filing date. Thaler filed those forms naming DABUS as the inventor and explaining in some detail why he believed that machines should be regarded as inventors in the circumstances. His application was rejected on the grounds that: (1) naming a machine as inventor did not meet the requirements of the Patents Act 1977; and (2) the IPO was not satisfied as to the manner in which Thaler had acquired rights that would otherwise vest in the inventor. Thaler was not satisfied with the decision and asked for a hearing before an official known as the "hearing officer". By a decision dated 4 December 2019 the hearing officer rejected Thaler's appeal. Thaler appealed against the hearing officer's decision to the Patents Court (a specialist court within the Chancery Division of the High Court of England and Wales that determines patent disputes). On 21 September 2020, Mr Justice Marcus Smith upheld the decision of the hearing officer. On 21 September 2021, Thaler's further appeal to the Court of Appeal was dismissed by Arnold LJ and Laing LJ (Birss LJ dissenting). On 20 December 2023, the UK Supreme Court dismissed a further appeal by Thaler. In its judgment, the court held that an "inventor" under the Patents Act 1977 must be a natural person. === United States === The patent applications on the inventions were refused by the USPTO, which held that only natural persons can be named as inventors in a patent application. Thaler first fought this result by filing a complaint under the Administrative Procedure Act alleging that the decision was "arbitrary, capricious, an abuse of discretion and not in accordance with the law; unsupported by substantial evidence, and in excess of Defendants’ statutory authority." A month later on August 19, 2019, Thaler filed a petition with the USPTO as allowed in 37 C.F.R. § 1.181 stating that DABUS should be the inventor. The judge and Thaler agreed in this case that Thaler himself is unable to receive the patent on behalf of DABUS. In their August 5, 2022, Thaler decision, the US Court of Appeals for the Federal Circuit affirmed that only a natural person could be an inventor, which means that the AI that invents any other type of invention is not addressed by the "who" mentioned in the legislation. === New Zealand === On January 31, 2022, the Intellectual Property Office of New Zealand (IPONZ) decided that a patent application (776029) filed by Stephen Thaler was void, on the basis that no inventor was identified on the patent application. IPONZ determined that DABUS could not be "an actual devisor of the invention" as required by the Patents Act 2013, and that this must be a natural person as held by the previous patent offices above. The High Court of New Zealand confirmed the decision in 2023. === South Africa === On 24 June 2021, the South African Companies and Intellectual Property Commission (CIPC) accepted Dr Thaler's Patent Cooperation Treaty, for a patent in respect of inventions generated by DABUS. In July 2021, the CIPC released a notice of issuance for the patent. It is the first patent granted for an AI invention. === Switzerland === On June 26, 2025, the Swiss Federal Administrative Court ruled that artificial intelligence systems such as DABUS cannot be listed as inventors in patent applications. The court upheld the existing practice of the Swiss Federal Institute of Intellectual Property (IPI), which requires that only natural persons can be recognized as inventors under Swiss patent law. The case concerned a patent application, which sought to designate DABUS as the sole inventor of a food container designed with a fractal geometry to enhance heat distribution. The IPI had rejected the application, arguing that both the absence of a human inventor and the attribution of inventorship to an AI system were inadmissible. While the court dismissed Thaler's main request, it accepted a subsidiary request: if a human applicant recognizes and files a patent based on an AI-generated invention, that person may be considered the inventor. As a result, the application may proceed with Thaler listed as the inventor. The decision (B-2532/2024) can still be appealed to the Swiss Federal Supreme Court.

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  Artificial psychology

  Artificial psychology (AP) has had multiple meanings dating back to 19th century, with recent usage related to artificial intelligence (AI).Artificial psychology is a theoretical field related to artificial intelligence, cognitive science, and psychology, which explores how advanced AI systems may develop human-like decision-making processes. In 1999, Zhiliang Wang and Lun Xie presented a theory of artificial psychology based on artificial intelligence. They analyze human psychology using information science research methods and artificial intelligence research to probe deeper into the human mind. == Main Theory == Dan Curtis (b. 1963) proposed AP is a theoretical discipline. The theory considers the situation when an artificial intelligence approaches the level of complexity where the intelligence meets two conditions: Condition I A: Makes all of its decisions autonomously B: Is capable of making decisions based on information that is New Abstract Incomplete C: The artificial intelligence is capable of reprogramming itself based on the new data, allowing it to evolve. D: And is capable of resolving its own programming conflicts, even in the presence of incomplete data. This means that the intelligence autonomously makes value-based decisions, referring to values that the intelligence has created for itself. Condition II All four criteria are met in situations that are not part of the original operating program When both conditions are met, then, according to this theory, the possibility exists that the intelligence will reach irrational conclusions based on real or created information. At this point, the criteria are met for intervention which will not necessarily be resolved by simple re-coding of processes due to extraordinarily complex nature of the codebase itself; but rather a discussion with the intelligence in a format which more closely resembles classical (human) psychology. If the intelligence cannot be reprogrammed by directly inputting new code, but requires the intelligence to reprogram itself through a process of analysis and decision based on information provided by a human, in order for it to overcome behavior which is inconsistent with the machines purpose or ability to function normally, then artificial psychology is by definition, what is required. The level of complexity that is required before these thresholds are met is currently a subject of extensive debate. The theory of artificial psychology does not address the specifics of what those levels may be, but only that the level is sufficiently complex that the intelligence cannot simply be recoded by a software developer, and therefore dysfunctionality must be addressed through the same processes that humans must go through to address their own dysfunctionalities. Along the same lines, artificial psychology does not address the question of whether or not the intelligence is conscious. As of 2022, the level of artificial intelligence does not approach any threshold where any of the theories or principles of artificial psychology can even be tested, and therefore, artificial psychology remains a largely theoretical discipline. Even at a theoretical level, artificial psychology remains an advanced stage of artificial intelligence.

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  DeepSeek (chatbot)

  DeepSeek is a generative artificial intelligence chatbot developed by the Chinese company DeepSeek. Released on 20 January 2025, DeepSeek-R1 surpassed ChatGPT as the most downloaded freeware app on the iOS App Store in the United States by 27 January. DeepSeek's success against larger and more established rivals has been described as "upending AI" and initiating "a global AI space race". DeepSeek's compliance with Chinese government censorship policies and its data collection practices have also raised concerns over privacy and information control in the model, prompting regulatory scrutiny in multiple countries. However, it has also been praised for its open weights and infrastructure code, energy efficiency and contributions to open-source artificial intelligence. == History == On 10 January 2025, DeepSeek released the chatbot, based on the DeepSeek-R1 model, for iOS and Android. By 27 January, DeepSeek-R1 surpassed ChatGPT as the most-downloaded freeware app on the iOS App Store in the United States, which resulted in an 18% drop in Nvidia's share price. And after a "large-scale" cyberattack on the same day disrupted the proper functioning of its servers, DeepSeek had limited its new user registration to phone numbers from mainland China, email addresses, or Google account logins. On 3 April 2025, in collaboration with researchers at Tsinghua University, DeepSeek published a paper unveiling a new model that combines the techniques generative reward modeling (GRM) and self-principled critique tuning (SPCT). The resulting model is referred to as DeepSeek-GRM. The goal of using these techniques is to foster more effective inference-time scaling within their LLM and chatbot services. Notably, DeepSeek has said that these new models will be released and made open source. On 30 April 2025, Deepseek released its math-focused Artificial Intelligence Model named "DeepSeek-Prover-V2-671B". This model is useful for formal theorem proving and mathematical reasoning. On 24 April 2026, DeepSeek released DeepSeek V4 and V4-Pro. == Usage == DeepSeek can answer questions, solve logic problems, and write computer programs on par with other chatbots, according to benchmark tests used by American AI companies. Users can access the chatbot for free through the official DeepSeek website or mobile application, without limitation on the number of queries. DeepSeek only supports user-signup via a global email service, e.g. Gmail, Google or Yahoo. DeepSeek also offers access to the R1 and V3 models that power the chatbot via an API with a usage-based pricing model. This modality is primarily targeted towards developers and businesses. As of February 2025, API usage is priced at approximately $0.28 per million input tokens and $0.42 per million output tokens, making it less expensive than some competing services. Its web version is completely free, with 500 messages per hour cap limit to prevent bots from spamming. == Operation == DeepSeek-V3 uses significantly fewer resources compared to its peers. For example, whereas the world's leading AI companies train their chatbots with supercomputers using as many as 16,000 graphics processing units (GPUs), DeepSeek claims to have needed only about 2,000 GPUs—namely, the H800 series chips from Nvidia. It was trained in around 55 days at a cost of US$5.58 million, which is roughly one-tenth of what tech giant Meta spent building its latest AI technology. == Reactions == DeepSeek's success against larger and more established rivals has been described as "upending AI", constituting "the first shot at what is emerging as a global AI space race", and ushering in "a new era of AI brinkmanship". === Challenge to US AI dominance === DeepSeek's competitive performance at relatively minimal cost has been recognized as potentially challenging the global dominance of American AI models. Various publications and news media, such as The Hill and The Guardian, have described the release of the R1 chatbot as a "Sputnik moment" for American AI, echoing Marc Andreessen's view. OpenAI wrote a letter to the Office of Science and Technology Policy (OSTP), in March 2025, citing issues concerning a possibility that Deepseek could manipulate responses to cause harm. === Chinese perspective === DeepSeek's founder Liang Wenfeng has been compared to OpenAI CEO Sam Altman, with CNN calling him the Sam Altman of China and an evangelist for AI. Chinese state media widely praised DeepSeek as a national asset. On 20 January 2025, Chinese Premier Li Qiang invited Wenfeng to his symposium with experts and asked him to provide opinions and suggestions on a draft for comments of the annual 2024 government work report. On 20 February 2025, Wenfeng met with General Secretary of the Chinese Communist Party Xi Jinping, who encouraged party and state leaders to experiment with DeepSeek. Government officials responded to Xi's approval of the chatbot by reportedly using it to draft legal judgements, propose medical treatment plans, and analyze surveillance videos to search for missing persons. === Performance and success === Leading figures in the American AI sector had mixed reactions to DeepSeek's performance and success. Microsoft CEO Satya Nadella and OpenAI CEO Altman—whose companies are involved in the United States government-backed "Stargate Project" to develop American AI infrastructure—both called DeepSeek "super impressive". Various companies including Amazon Web Services, Toyota, and Stripe are seeking to use the model in their program. When American President Donald Trump announced The Stargate Project, he referred to DeepSeek as a wake-up call and a positive development. Other leaders in the AI field, however—including Scale AI CEO Alexandr Wang, Anthropic cofounder and CEO Dario Amodei, and Elon Musk—have expressed skepticism of the app's performance or of the sustainability of its success. Wang in particularly referred to DeepSeek-V3 as "earth-shattering" and DeepSeek-R1 as "top performing, or roughly on par with the best American models", but speculated that China may possess more AI-powering Nvidia H100 GPUs than thought. === Stock market implications === DeepSeek's optimization of limited resources has highlighted potential limits of United States sanctions on China's AI development, including export restrictions on advanced AI chips to China. The success of the company's AI models consequently "sparked market turmoil" and caused shares in major global technology companies to plunge on 27 January 2025: Nvidia's stock fell by as much as 17–18%, as did the stock of rival Broadcom. Other tech firms also sank, including Microsoft (down 2.5%), Google's owner Alphabet (down over 4%), and Dutch chip equipment maker ASML (down over 7%). A global sell-off of technology stocks on Nasdaq, prompted by the release of the R1 model, led to record losses of about $593 billion in the market capitalizations of AI and computer hardware companies; and by the next day a total of $1 trillion of value was wiped from American stocks. == Concerns == === Distillation === DeepSeek has been reported to sometimes claim that it is ChatGPT. OpenAI said that DeepSeek may have "inappropriately" used outputs from its model as training data in a process called distillation. However, there is currently no method to prove this conclusively. === Censorship === DeepSeek's compliance with Chinese government censorship policies and its data collection practices have raised concerns over information control in the model, prompting regulatory scrutiny in multiple countries. Reports indicate that it applies content moderation in accordance with the government's "public opinion guidance" regulations, limiting responses on topics such as the Tiananmen Square massacre and Taiwan's political status. DeepSeek models that have been uncensored also display a bias towards Chinese government viewpoints on controversial topics such as Xi Jinping's human rights record and Taiwan's political status. However, users who have downloaded the models and hosted them on their own devices and servers have reported successfully removing this censorship. Some sources have observed that the official application programming interface (API) version of R1, which runs from servers located in mainland China, uses censorship mechanisms for topics considered politically sensitive for the government of China. For example, the model may initially generate answers to questions about the 1989 Tiananmen Square massacre, persecution of Uyghurs, comparisons between Xi Jinping and Winnie the Pooh, and human rights in China, but a censorship mechanism deletes the uncensored response afterwards and replaces it with a message such as:"Sorry, that's beyond my current scope. Let's talk about something else." The post hoc censorship mechanisms and restrictions added on top of the model's output can be removed in the open-source version of the R1 model. If the "core Socialist values" defined by the Chinese Internet regul

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  Computational intelligence

  In computer science, computational intelligence (CI) refers to concepts, paradigms, algorithms and implementations of systems that are designed to show "intelligent" behavior in complex and changing environments. These systems are aimed at mastering complex tasks in a wide variety of technical or commercial areas and offer solutions that recognize and interpret patterns, control processes, support decision-making or autonomously manoeuvre vehicles or robots in unknown environments, among other things. These concepts and paradigms are characterized by the ability to learn or adapt to new situations, to generalize, to abstract, to discover and associate. Nature-analog or nature-inspired methods play a key role in this. CI approaches primarily address those complex real-world problems for which traditional or mathematical modeling is not appropriate for various reasons: the processes cannot be described exactly with complete knowledge, the processes are too complex for mathematical reasoning, they contain some uncertainties during the process, such as unforeseen changes in the environment or in the process itself, or the processes are simply stochastic in nature. Thus, CI techniques are properly aimed at processes that are ill-defined, complex, nonlinear, time-varying and/or stochastic. A recent definition of the IEEE Computational Intelligence Societey describes CI as the theory, design, application and development of biologically and linguistically motivated computational paradigms. Traditionally the three main pillars of CI have been Neural Networks, Fuzzy Systems and Evolutionary Computation. ... CI is an evolving field and at present in addition to the three main constituents, it encompasses computing paradigms like ambient intelligence, artificial life, cultural learning, artificial endocrine networks, social reasoning, and artificial hormone networks. ... Over the last few years there has been an explosion of research on Deep Learning, in particular deep convolutional neural networks. Nowadays, deep learning has become the core method for artificial intelligence. In fact, some of the most successful AI systems are based on CI. However, as CI is an emerging and developing field there is no final definition of CI, especially in terms of the list of concepts and paradigms that belong to it. The general requirements for the development of an “intelligent system” are ultimately always the same, namely the simulation of intelligent thinking and action in a specific area of application. To do this, the knowledge about this area must be represented in a model so that it can be processed. The quality of the resulting system depends largely on how well the model was chosen in the development process. Sometimes data-driven methods are suitable for finding a good model and sometimes logic-based knowledge representations deliver better results. Hybrid models are usually used in real applications. According to actual textbooks, the following methods and paradigms, which largely complement each other, can be regarded as parts of CI: Fuzzy systems Neural networks and, in particular, convolutional neural networks Evolutionary computation and, in particular, multi-objective evolutionary optimization Swarm intelligence Bayesian networks Artificial immune systems Learning theory Probabilistic methods == Relationship between hard and soft computing and artificial and computational intelligence == Artificial intelligence (AI) is used in the media, but also by some of the scientists involved, as a kind of umbrella term for the various techniques associated with it or with CI. Craenen and Eiben state that attempts to define or at least describe CI can usually be assigned to one or more of the following groups: "Relative definition” comparing CI to AI Conceptual treatment of key notions and their roles in CI Listing of the (established) areas that belong to it The relationship between CI and AI has been a frequently discussed topic during the development of CI. While the above list implies that they are synonyms, the vast majority of AI/CI researchers working on the subject consider them to be distinct fields, where either CI is an alternative to AI AI includes CI CI includes AI The view of the first of the above three points goes back to Zadeh, the founder of the fuzzy set theory, who differentiated machine intelligence into hard and soft computing techniques, which are used in artificial intelligence on the one hand and computational intelligence on the other. In hard computing (HC) and traditional AI (e.g. expert systems), inaccuracy and uncertainty are undesirable characteristics of a system, while soft computing (SC) and thus CI focus on dealing with these characteristics. The adjacent figure illustrates this view and lists the most important CI techniques. Another frequently mentioned distinguishing feature is the representation of information in symbolic form in AI and in sub-symbolic form in CI techniques. Hard computing is a conventional computing method based on the principles of certainty and accuracy and it is deterministic. It requires a precisely stated analytical model of the task to be processed and a prewritten program, i.e. a fixed set of instructions. The models used are based on Boolean logic (also called crisp logic), where e.g. an element can be either a member of a set or not and there is nothing in between. When applied to real-world tasks, systems based on HC result in specific control actions defined by a mathematical model or algorithm. If an unforeseen situation occurs that is not included in the model or algorithm used, the action will most likely fail. Soft computing, on the other hand, is based on the fact that the human mind is capable of storing information and processing it in a goal-oriented way, even if it is imprecise and lacks certainty. SC is based on the model of the human brain with probabilistic thinking, fuzzy logic and multi-valued logic. Soft computing can process a wealth of data and perform a large number of computations, which may not be exact, in parallel. For hard problems for which no satisfying exact solutions based on HC are available, SC methods can be applied successfully. SC methods are usually stochastic in nature i.e., they are a randomly defined processes that can be analyzed statistically but not with precision. Up to now, the results of some CI methods, such as deep learning, cannot be verified and it is also not clear what they are based on. This problem represents an important scientific issue for the future. AI and CI are catchy terms, but they are also so similar that they can be confused. The meaning of both terms has developed and changed over a long period of time, with AI being used first. Bezdek describes this impressively and concludes that such buzzwords are frequently used and hyped by the scientific community, science management and (science) journalism. Not least because AI and biological intelligence are emotionally charged terms and it is still difficult to find a generally accepted definition for the basic term intelligence. == History == In 1950, Alan Turing, one of the founding fathers of computer science, developed a test for computer intelligence known as the Turing test. In this test, a person can ask questions via a keyboard and a monitor without knowing whether his counterpart is a human or a computer. A computer is considered intelligent if the interrogator cannot distinguish the computer from a human. This illustrates the discussion about intelligent computers at the beginning of the computer age. The term Computational Intelligence was first used as the title of the journal of the same name in 1985 and later by the IEEE Neural Networks Council (NNC), which was founded 1989 by a group of researchers interested in the development of biological and artificial neural networks. On November 21, 2001, the NNC became the IEEE Neural Networks Society, to become the IEEE Computational Intelligence Society two years later by including new areas of interest such as fuzzy systems and evolutionary computation. The NNC helped organize the first IEEE World Congress on Computational Intelligence in Orlando, Florida in 1994. On this conference the first clear definition of Computational Intelligence was introduced by Bezdek: A system is computationally intelligent when it: deals with only numerical (low-level) data, has pattern-recognition components, does not use knowledge in the AI sense; and additionally when it (begins to) exhibit (1) computational adaptivity; (2) computational fault tolerance; (3) speed approaching human-like turnaround and (4) error rates that approximate human performance. Today, with machine learning and deep learning in particular utilizing a breadth of supervised, unsupervised, and reinforcement learning approaches, the CI landscape has been greatly enhanced, with novell intelligent approaches. == The main algorithmic approaches of CI and their applicati

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  Neural computation

  Neural computation is the information processing performed by networks of neurons. Neural computation is affiliated with the philosophical tradition of computationalism, which advances the thesis that neural computation explains cognition. Warren McCulloch and Walter Pitts were the first to propose an account of neural activity as being computational in their seminal 1943 paper "A Logical Calculus of the Ideas Immanent in Nervous Activity." There are three general branches of computationalism, including classicism, connectionism, and computational neuroscience. All three branches agree that cognition is computation, however, they disagree on what sorts of computations constitute cognition. The classicism tradition believes that computation in the brain is digital, analogous to digital computing. Both connectionism and computational neuroscience do not require that the computations that realize cognition are necessarily digital computations. However, the two branches greatly disagree upon which sorts of experimental data should be used to construct explanatory models of cognitive phenomena. Connectionists rely upon behavioral evidence to construct models to explain cognitive phenomena, whereas computational neuroscience leverages neuroanatomical and neurophysiological information to construct mathematical models that explain cognition. When comparing the three main traditions of the computational theory of mind, as well as the different possible forms of computation in the brain, it is helpful to define what we mean by computation in a general sense. Computation is the processing of information, otherwise known as variables or entities, according to a set of rules. A rule in this sense is simply an instruction for executing a manipulation on the current state of the variable, in order to produce a specified output. In other words, a rule dictates which output to produce given a certain input to the computing system. A computing system is a mechanism whose components must be functionally organized to process the information in accordance with the established set of rules. The types of information processed by a computing system determine which type of computations it performs. Traditionally in cognitive science, there have been two proposed types of computation related to neural activity, digital and analog, with the vast majority of theoretical work incorporating a digital understanding of cognition. Computing systems that perform digital computation are functionally organized to execute operations on strings of digits with respect to the type and location of the digit on the string. It has been argued that neural spike train signaling implements some form of digital computation, since neural spikes may be considered as discrete units or digits, like 0 or 1—the neuron either fires an action potential or it does not. Accordingly, neural spike trains could be seen as strings of digits. Alternatively, analog computing systems perform manipulations on non-discrete, irreducibly continuous variables, that is, entities that vary continuously as a function of time. These sorts of operations are characterized by systems of differential equations. Neural computation can be studied by, for example, building models of neural computation. Work on artificial neural networks has been somewhat inspired by knowledge of neural computation.

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  Apprenticeship learning

  In artificial intelligence, apprenticeship learning (or learning from demonstration or imitation learning) is the process of learning by observing an expert. It can be viewed as a form of supervised learning, where the training dataset consists of task executions by a demonstration teacher. == Mapping function approach == Mapping methods try to mimic the expert by forming a direct mapping either from states to actions, or from states to reward values. For example, in 2002 researchers used such an approach to teach an AIBO robot basic soccer skills. === Inverse reinforcement learning approach === Inverse reinforcement learning (IRL) is the process of deriving a reward function from observed behavior. While ordinary "reinforcement learning" involves using rewards and punishments to learn behavior, in IRL the direction is reversed, and a robot observes a person's behavior to figure out what goal that behavior seems to be trying to achieve. The IRL problem can be defined as: Given 1) measurements of an agent's behaviour over time, in a variety of circumstances; 2) measurements of the sensory inputs to that agent; 3) a model of the physical environment (including the agent's body): Determine the reward function that the agent is optimizing. IRL researcher Stuart J. Russell proposes that IRL might be used to observe humans and attempt to codify their complex "ethical values", in an effort to create "ethical robots" that might someday know "not to cook your cat" without needing to be explicitly told. The scenario can be modeled as a "cooperative inverse reinforcement learning game", where a "person" player and a "robot" player cooperate to secure the person's implicit goals, despite these goals not being explicitly known by either the person nor the robot. In 2017, OpenAI and DeepMind applied deep learning to the cooperative inverse reinforcement learning in simple domains such as Atari games and straightforward robot tasks such as backflips. The human role was limited to answering queries from the robot as to which of two different actions were preferred. The researchers found evidence that the techniques may be economically scalable to modern systems. Apprenticeship via inverse reinforcement learning (AIRP) was developed by in 2004 Pieter Abbeel, Professor in Berkeley's EECS department, and Andrew Ng, Associate Professor in Stanford University's Computer Science Department. AIRP deals with "Markov decision process where we are not explicitly given a reward function, but where instead we can observe an expert demonstrating the task that we want to learn to perform". AIRP has been used to model reward functions of highly dynamic scenarios where there is no obvious reward function intuitively. Take the task of driving for example, there are many different objectives working simultaneously - such as maintaining safe following distance, a good speed, not changing lanes too often, etc. This task, may seem easy at first glance, but a trivial reward function may not converge to the policy wanted. One domain where AIRP has been used extensively is helicopter control. While simple trajectories can be intuitively derived, complicated tasks like aerobatics for shows has been successful. These include aerobatic maneuvers like - in-place flips, in-place rolls, loops, hurricanes and even auto-rotation landings. This work was developed by Pieter Abbeel, Adam Coates, and Andrew Ng - "Autonomous Helicopter Aerobatics through Apprenticeship Learning" === System model approach === System models try to mimic the expert by modeling world dynamics. == Plan approach == The system learns rules to associate preconditions and postconditions with each action. In one 1994 demonstration, a humanoid learns a generalized plan from only two demonstrations of a repetitive ball collection task. == Example == Learning from demonstration is often explained from a perspective that the working Robot-control-system is available and the human-demonstrator is using it. And indeed, if the software works, the Human operator takes the robot-arm, makes a move with it, and the robot will reproduce the action later. For example, he teaches the robot-arm how to put a cup under a coffeemaker and press the start-button. In the replay phase, the robot is imitating this behavior 1:1. But that is not how the system works internally; it is only what the audience can observe. In reality, Learning from demonstration is much more complex. One of the first works on learning by robot apprentices (anthropomorphic robots learning by imitation) was Adrian Stoica's PhD thesis in 1995. In 1997, robotics expert Stefan Schaal was working on the Sarcos robot-arm. The goal was simple: solve the pendulum swingup task. The robot itself can execute a movement, and as a result, the pendulum is moving. The problem is, that it is unclear what actions will result into which movement. It is an Optimal control-problem which can be described with mathematical formulas but is hard to solve. The idea from Schaal was, not to use a Brute-force solver but record the movements of a human-demonstration. The angle of the pendulum is logged over three seconds at the y-axis. This results into a diagram which produces a pattern. In computer animation, the principle is called spline animation. That means, on the x-axis the time is given, for example 0.5 seconds, 1.0 seconds, 1.5 seconds, while on the y-axis is the variable given. In most cases it's the position of an object. In the inverted pendulum it is the angle. The overall task consists of two parts: recording the angle over time and reproducing the recorded motion. The reproducing step is surprisingly simple. As an input we know, in which time step which angle the pendulum must have. Bringing the system to a state is called “Tracking control” or PID control. That means, we have a trajectory over time, and must find control actions to map the system to this trajectory. Other authors call the principle “steering behavior”, because the aim is to bring a robot to a given line.

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  OrCam device

  OrCam devices such as OrCam MyEye are portable, artificial vision devices that allow visually impaired people to understand text and identify objects through audio feedback, describing what they are unable to see. Reuters described an important part of how it works as "a wireless smartcamera" which, when attached outside eyeglass frames, can read and verbalize text, and also supermarket barcodes. This information is converted to spoken words and entered "into the user’s ear." Face-recognition is also part of OrCam's feature set. == Devices == OrCam Technologies Ltd has created three devices; OrCam MyEye 2.0, OrCam MyEye 1, and OrCam MyReader. OrCam My Eye 2.0: OrCam debuted the second-generation model, the OrCam MyEye 2.0 in December 2017. About the size of a finger, the MyEye 2.0 is battery-powered, and has been compressed into a self-contained device. The device snaps onto any eyeglass frame magnetically. Orcam 2.0 is small and light (22.5 grams/0.8 ounces) with functionality to restore independence to the visually impaired. It comes in two versions. The basic model can read text, and a more advanced one adds features such as face recognition and barcode reading. As of July 2023, the retail cost is between $4000 and $6000 (USD). == Clinical Studies == JAMA Ophthalmology: In 2016 JAMA Ophthalmology conducted a study involving 12 legally blind participants to evaluate the usefulness of a portable artificial vision device (OrCam) for patients with low vision. The results showed that the OrCam device improved the patient's ability to perform tasks simulating those of daily living, such as reading a message on an electronic device, a newspaper article or a menu. Wills Eye: Wills Eye was a clinical study designed to measure the impact of the OrCam device on the quality of life of patients with End-stage Glaucoma. The conclusion was that OrCam, a novel artificial vision device using a mini-camera mounted on eyeglasses, allowed legally blind patients with end-stage glaucoma to read independently, subsequently improving their quality of life. == Employee testing == The New York Times described how a pre-release OrCam device was used by a Coloboma-impaired employee of the device's developer in 2013 for grocery shopping. It was the small size of the prototype rather than the functionality that gave her added mobility in an Israeli store's aisles. Added life-enhancement was described: "to both recognize and speak .. bus numbers .. traffic lights." == Social aspects == In contrast to an early version of Google Glass, which "failed ... because .. Glass wearers were ..mocked", early OrCam devices used designs that "clip unobtrusively on your shirt or perhaps your belt." In addition, it does not record sounds or images, what was called "the privacy puzzle that stumped Google. One 2018 technology reviewer wrote that he wished it had a headphone jack "so it would be less disruptive in places where others are working." An attempt was made to use bone conduction. == USA introduction == In 2018 a team headed by New York Assemblyman Dov Hikind introduced use of OrCam devices to ten individuals screened for what he termed "new Israeli technology that really makes a difference to the blind." Although not the first USA success, it was more focused than a publicly funded project that was authorized in 2016 by a California government agency. Also in 2016 the Chicago Lighthouse for the Blind demonstrated its use. == Technology == In the area of hardware, miniaturization has been quite important, but one major area, software, was mentioned by Assemblyman Hikind, and reported by The Times of Israel is the "AI-driven algorithms" that "reports .. how many people are in a room. In addition to reading printed text, it can also aid in "seeing" what is on a television or computer screen. Although OrCam can't help with handwritten information, it can reuse information, the basis of recognizing "US currency, and even faces." === Features === While early language support was for English, French, German, Hebrew and Spanish, others now available include Danish, Dutch, Finnish, Italian, Norwegian, Portuguese and Swedish. == History == OrCam Technologies Ltd was founded in 2010 by Professor Amnon Shashua and Ziv Aviram. Before co-founding OrCam, the two in 1999 co-founded Mobileye, an Israeli company that develops vision-based advanced driver-assistance systems (ADAS) providing warnings for collision prevention and mitigation, which was acquired by Intel for $15.3 billion in 2017. OrCam launched OrCam MyEye in 2013 after years of development and testing, and began selling it commercially in 2015. In its early years, the company raised $22 million, $6 million of which came from Intel Capital. By 2014, Intel, which was also investing in Google Glass, had invested $15 million in Orcam. In March 2017, OrCam had raised $41 million in capital, making it worth $600 million. === Marketing === One outcome of initial marketing in the USA was that they "reached a deal with the California Department of Rehabilitation, ...qualifying blind and visually impaired state residents." == OrCam Technologies Ltd == OrCam Technologies Ltd. is the Israeli-based company producing these OrCam devices, which are wearable artificial intelligence space. The company develops and manufactures assistive technology devices for individuals who are visually impaired, partially sighted, blind, print disabilities, or have other disabilities. OrCam headquarters is located in Jerusalem, operating under the company name OrCam Technologies Ltd. OrCam has over 150 employees, is headquartered in Jerusalem, and has offices in New York, Toronto, and London. == Awards == 2018 Last Gadget Standing Winner 2018 CES Innovation Awards Honoree in Accessible Tech 2017 NAIDEX Innovation Award 2016 Louise Braille Corporate Recognition Award 2016 Silmo-d-Or Award

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  Moral outsourcing

  Moral outsourcing is the placing of responsibility for ethical decision-making onto external entities, often algorithms. The term is often used in discussions of computer science and algorithmic fairness, but it can apply to any situation in which one appeals to outside agents in order to absolve themselves of responsibility for their actions. In this context, moral outsourcing specifically refers to the tendency of society to blame technology, rather than its creators or users, for any harm it may cause. == Definition == The term "moral outsourcing" was first coined by Dr. Rumman Chowdhury, a data scientist concerned with the overlap between artificial intelligence and social issues. Chowdhury used the term to describe looming fears of a so-called “Fourth Industrial Revolution” following the rise of artificial intelligence. Moral outsourcing is often applied by technologists to shrink away from their part in building offensive products. In her TED Talk, Chowdhury gives the example of a creator excusing their work by saying they were simply doing their job. This is a case of moral outsourcing and not taking ownership for the consequences of creation. When it comes to AI, moral outsourcing allows for creators to decide when the machine is human and when it is a computer - shifting the blame and responsibility of moral plights off of the technologists and onto the technology. Conversations around AI and bias and its impacts require accountability to bring change. It is difficult to address these biased systems if their creators use moral outsourcing to avoid taking any responsibility for the issue. One example of moral outsourcing is the anger that is directed at machines for “taking jobs away from humans” rather than companies for employing that technology and jeopardizing jobs in the first place. The term "moral outsourcing" refers to the concept of outsourcing, or enlisting an external operation to complete specific work for another organization. In the case of moral outsourcing, the work of resolving moral dilemmas or making choices according to an ethical code is supposed to be conducted by another entity. == Real-world applications == In the medical field, AI is increasingly involved in decision-making processes about which patients to treat, and how to treat them. The responsibility of the doctor to make informed decisions about what is best for their patients is outsourced to an algorithm. Sympathy is also noted to be an important part of medical practice; an aspect that artificial intelligence, glaringly, is missing. This form of moral outsourcing is a major concern in the medical community. Another field of technology in which moral outsourcing is frequently brought up is autonomous vehicles. California Polytechnic State University professor Keith Abney proposed an example scenario: "Suppose we have some [troublemaking] teenagers, and they see an autonomous vehicle, they drive right at it. They know the autonomous vehicle will swerve off the road and go off a cliff, but should it?" The decision of whether to sacrifice the autonomous vehicle (and any passengers inside) or the vehicle coming at it will be written into the algorithms defining the car's behavior. In the case of moral outsourcing, the responsibility of any damage caused by an accident may be attributed to the autonomous vehicle itself, rather than the creators who wrote the protocol the vehicle will use to "decide" what to do. Moral outsourcing is also used to delegate the consequences of predictive policing algorithms to technology, rather than the creators or the police. There are many ethical concerns with predictive policing due to the fact that it results in the over-policing of low income and minority communities. In the context of moral outsourcing, the positive feedback loop of sending disproportionate police forces into minority communities is attributed to the algorithm and the data being fed into this system--rather than the users and creators of the predictive policing technology. == Outside of technology == === Religion === Moral outsourcing is also commonly seen in appeals to religion to justify discrimination or harm. In his book What It Means to be Moral, sociologist Phil Zuckerman contradicts the popular religious notion that morality comes from God. Religion is oftentimes cited as a foundation for a moral stance without any tangible relation between the religious beliefs and personal stance. In these cases, religious individuals will "outsource" their personal beliefs and opinions by claiming that they are a result of their religious identification. This is seen where religion is cited as a factor for political beliefs, medical beliefs, and in extreme cases an excuse for violence. === Manufacturing === Moral outsourcing can also be seen in the business world in terms of manufacturing goods and avoiding environmental responsibility. Some companies in the United States will move their production process to foreign countries with more relaxed environmental policies to avoid the pollution laws that exist in the US. A study by the Harvard Business Review found that "in countries with tight environmental regulation, companies have 29% lower domestic emissions on average. On the other hand, such a tightening in regulation results in 43% higher emissions abroad." The consequences of higher pollution rates are then attributed to the loose regulations in these countries, rather than on the companies themselves who purposefully moved into these areas to avoid strict pollution policy.

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  Data-centric AI

  Data-centric AI is an approach within artificial intelligence that emphasizes on improving the quality, consistency and representativeness of the data used to train machine learning models, rather than focusing primarily on optimizing model architectures or algorithms. This idea has gained traction as researchers and practitioners have come to believe that many performance limitations of machine learning systems stem from issues such as noisy labels, biased datasets, and lack of coverage in the data. Data-centric AI involves disciplined approach to data cleaning, augmentation, labeling, and governance that improves model performance and reliability in applications such as computer vision, natural language processing, and further.

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