AI Analytics Masters

AI Analytics Masters — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

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  KeyBase

  KeyBase is a database and web application for managing and deploying interactive taxonomic keys for plants and animals developed by the Royal Botanic Gardens Victoria. KeyBase provides a medium where pathway keys which were traditionally developed for print and other classical types of media, can be used more effectively in the internet environment. The platform uses a concept called "keys" which can be easily linked together, joined with other keys, or merged into larger other seamless keys groups, with each still available to be browsed independently. Keys in the KeyBase database can be filtered and displayed in a variety of ways, filters, and formats.

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  Thirst trap

  A thirst trap is a type of social media post intended to entice viewers sexually. It refers to a viewer's "thirst", a colloquialism likening sexual frustration to dehydration, implying desperation, with the afflicted individual being described as "thirsty". The phrase entered into the lexicon in the late 1990s, but is most related to Internet slang that developed in the early 2010s. Its meaning has changed over time, previously referring to a graceless need for approval, affection or attention. == History == The term thirst trap originated within selfie culture, though its precise origins remain unclear. An early use of the phrase with reference to dehydration appears in the 1999 book Running for Dummies by Florence Griffith Joyner and John Hanc, where it referred to the deceptive sensation of thirst being quenched after initial fluid intake, advising continued hydration to avoid the so-called "thirst trap." The modern usage of thirst trap resurfaced around 2011 on platforms such as Twitter and Urban Dictionary, coinciding with the growing popularity of Snapchat, Instagram, and dating apps like Tinder and Grindr. In 2011, Urban Dictionary defined it as "any statement used to intentionally create attention or 'thirst'." By 2018, the term had entered mainstream discourse, appearing in outlets such as The New York Times and GQ without the need for explanation. == Usage of the term == Often, the term thirst trap describes an attractive picture of an individual that they post online. Thirst trap can also describe a digital heartthrob. For instance, former Canadian prime minister Justin Trudeau has been described as a political thirst trap. It has also been described as a modern form of "fishing for compliments". == Motivation == Thirst trapping may be driven by a variety of motives. Individuals often seek attention through "likes" and comments on social media, which can offer a temporary sense of validation and improved self-esteem. It can also serve as an outlet for expressing one's sexuality or enhancing a personal brand. In some cases, sharing such content may provide financial gain. Others might post thirst traps to cope with emotional distress, such as after breakup, or to spite a former lover. Sharing a thirst trap has also been used as a way to connect in times of social isolation (e.g. COVID-19 pandemic). From a physiological standpoint, endorphins and neurotransmitters like oxytocin and dopamine are released during sexual contact. It has been speculated outside of the academic setting that sharing and engaging with thirst traps may elicit similar pleasure responses. == Methodology == Methodologies have developed to take an optimal thirst trap photo. Reporting for Vice magazine, Graham Isador found several of his social network contacts spent a lot of time considering how to take the best photo and what text they should use. They considered angles and lighting. Sometimes they made use of the self-timer feature available on some cameras. Often, body parts are put on display without being too explicit (e.g. bulges of male genitalia, breast cleavage, abdominal muscles, pectoral muscles, backs, buttocks). Often, the thirst trap is accompanied by a caption. For instance, in October 2019, actress Tracee Ellis Ross posted bikini pictures on Instagram with a caption that included the message: "I've worked so hard to feel good in my skin and to build a life that truly matches me and I'm in it and it feels good. ... No filter, no retouch 47 year old thirst trap! Boom!" On Instagram, #ThirstTrapThursdays is a popular tag. Followers reply in turn after a posting. == Variations == "Gatsbying" is a variation of the thirst trap, where one puts posts on social media to attract the attention of a particular individual. The term alludes to the novel The Great Gatsby where the character Jay Gatsby would throw extravagant parties to attract the attention of his love interest, Daisy. "Instagrandstanding" is an alternative name for this. "Wholesome trapping" has developed, where one posts pictures of more meaningful aspects of life, such as spending time with friends or doing outdoor activities. == Criticism == Psychotherapist Lisa Brateman has criticized thirst traps as an unhealthy method of receiving external validation. This desire for external validation can be addictive. Thirst traps can cause pressure to maintain a good physical appearance, and therefore cause self-esteem issues. Additionally, thirst traps are often highly choreographed and thus present a distorted perception of reality. The manufacturing of thirst traps can be limited when one enters a relationship or with time as the body ages. In some cases, thirst traps can lead to harassment and online bullying. In April 2020, model Chrissy Teigen posted a video of herself wearing a black one-piece swimsuit, and she received a multitude of negative comments that constituted bullying and body shaming.

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  Customer data management

  Customer data management (CDM) is the ways in which businesses keep track of their customer information and survey their customer base in order to obtain feedback. CDM includes a range of software or cloud computing applications designed to give large organizations rapid and efficient access to customer data. Surveys and data can be centrally located and widely accessible within a company, as opposed to being warehoused in separate departments. CDM encompasses the collection, analysis, organizing, reporting and sharing of customer information throughout an organization. Businesses need a thorough understanding of their customers’ needs if they are to retain and increase their customer base. Efficient CDM solutions provide companies with the ability to deal instantly with customer issues and obtain immediate feedback. As a result, customer retention and customer satisfaction can show marked improvement. According to a study by Aberdeen Group, "above-average and best-in-class companies... attain greater than 20% annual improvement in retention rates, revenues, data accuracy and partner/customer satisfaction rates." == Customer data management and cloud computing == Cloud computing offers an attractive choice for CDM in many companies due to its accessibility and cost-effectiveness. Businesses can decide who, within their company, should have the ability to create, adjust, analyze or share customer information. In December 2010, 52% of Information Technology (IT) professionals worldwide were deploying, or planning to deploy, cloud computing; this percentage is far higher in many countries. == Background == Customer data management, as a term, was coined in the 1990s, pre-dating the alternative term enterprise feedback management (EFM). CDM was introduced as a software solution that would replace earlier disc-based or paper-based surveys and spreadsheet data. Initially, CDM solutions were marketed to businesses as software, which were specific to one company, and often to one department within that company. This was superseded by application service providers (ASPs) where software was hosted for end user organizations, thus avoiding the necessity for IT professionals to deploy and support software. However, ASPs with their single-tenancy architecture were, in turn, superseded by software as a service (SaaS), engineered for multi-tenancy. By 2007 SaaS applications, giving businesses on-demand access to their customer information, were rapidly gaining popularity compared with ASPs. Cloud computing now includes SaaS and many prominent CDM providers offer cloud-based applications to their clients. In recent years, there has been a push away from the term EFM, with many of those working in this area advocating the slightly updated use of CDM. The return to the term CDM is largely based on the greater need for clarity around the solutions offered by companies, and on the desire to retire terminology veering on techno-jargon that customers may have a hard time understanding.

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  Dashboard (computing)

  In computer information systems, a dashboard is a type of graphical user interface which often provides at-a-glance views of data relevant to a particular objective or process through a combination of visualizations and summary information. In other usage, "dashboard" is another name for "progress report" or "report" and is considered a form of data visualization. The dashboard is often accessible by a web browser and is typically linked to regularly updating data sources. Dashboards are often interactive and facilitate users to explore the data themselves, usually by clicking into elements to view more detailed information. The term dashboard originates from the automobile dashboard where drivers monitor the major functions at a glance via the instrument panel. == History == The idea of digital dashboards followed the study of decision support systems in the 1970s. Early predecessors of the modern business dashboard were first developed in the 1980s in the form of Executive Information Systems (EISs). Due to problems primarily with data refreshing and handling, it was soon realized that the approach wasn't practical as information was often incomplete, unreliable, and spread across too many disparate sources. Thus, EISs hibernated until the 1990s when the information age quickened pace and data warehousing, and online analytical processing (OLAP) allowed dashboards to function adequately. Despite the availability of enabling technologies, the dashboard use didn't become popular until later in that decade, with the rise of key performance indicators (KPIs), and the introduction of Robert S. Kaplan and David P. Norton's balanced scorecard. In the late 1990s, Microsoft promoted a concept known as the Digital Nervous System and "digital dashboards" were described as being one leg of that concept. Today, the use of dashboards forms an important part of Business Performance Management (BPM). Initially dashboards were used for monitoring purposes, now with the advancement of technology, dashboards are being used for more analytical purposes. The use of dashboards has now been incorporating; scenario analysis, drill down capabilities, and presentation format flexibility. == Benefits == Digital dashboards allow managers to monitor the contribution of the various departments in their organization. In addition, they enable “rolling up” of information to present a consolidated view across an organization. To gauge exactly how well an organization is performing overall, digital dashboards allow you to capture and report specific data points from each department within the organization, thus providing a "snapshot" of performance. Benefits of using digital dashboards include: Visual presentation of performance measures Ability to identify and correct negative trends Measure efficiencies/inefficiencies Ability to generate detailed reports showing new trends Ability to make more informed decisions based on collected business intelligence Dashboards offers a holistic view of the entire business as it gives the manager a bird's eye view into the performance of sales, data inventory, web traffic, social media analytics and other associated data that is visually presented on a single dashboard. Dashboards lead to better management of marketing/financial strategies as a dashboard for the display of marketing data makes the process of marketing easier and more reliable as compared to doing it manually. Web analytics play a crucial role in shaping the marketing strategy of many businesses. Dashboards also facilitate for better tracking of sales and financial reporting as the data is more precise and in one area. Lastly, dashboards offer for better customer service through monitoring because they keep both the managers and the clients updated on the project progress through automated emails and notifications. == Align strategies and organizational goals == Gain total visibility of all systems instantly Quick identification of data outliers and correlations Consolidated reporting into one location Available on mobile devices to quickly access metrics == Classification == Dashboards can be broken down according to role and are either strategic, analytical, operational, or informational. Dashboards are the 3rd step on the information ladder, demonstrating the conversion of data to increasingly valuable insights. Strategic dashboards support managers at any level in an organization and provide the quick overview that decision-makers need to monitor the health and opportunities of the business. Dashboards of this type focus on high-level measures of performance and forecasts. Strategic dashboards benefit from static snapshots of data (daily, weekly, monthly, and quarterly) that are not constantly changing from one moment to the next. Dashboards for analytical purposes often include more context, comparisons, and history, along with subtler performance evaluators. In addition, analytical dashboards typically support interactions with the data, such as drilling down into the underlying details. Dashboards for monitoring operations are often designed differently from those that support strategic decision making or data analysis and often require monitoring of activities and events that are constantly changing and might require attention and response at a moment's notice. == Types of dashboards == Digital dashboards may be laid out to track the flows inherent in the business processes that they monitor. Graphically, users may see the high-level processes and then drill down into low-level data. This level of detail is often buried deep within the corporate enterprise and otherwise unavailable to the senior executives. Three main types of digital dashboards dominate the market today: desktop software applications, web-browser-based applications, and desktop applications are also known as desktop widgets. The last are driven by a widget engine. Both Desktop and Browser-based providers enable the distribution of dashboards via a web browser. An example of the latter is web-based-browser Asana, which helps teams orchestrate their work, from daily tasks to strategic cross-functional initiatives. With it, teams can manage everything from company objectives to digital transformation to product launches and marketing campaigns. Specialized dashboards may track all corporate functions. Examples include human resources, recruiting, sales, operations, security, information technology, project management, customer relationship management, digital marketing and many more departmental dashboards. For a smaller organization like a startup a compact startup scorecard dashboard tracks important activities across lot of domains ranging from social media to sales. Digital dashboard projects involve business units as the driver and the information technology department as the enabler. Therefore, the success of dashboard projects depends on the relevancy/importance of information provided within the dashboard. This includes the metrics chosen to monitor and the timeliness of the data forming those metrics; data must be up to date and accurate. Key performance indicators, balanced scorecards, and sales performance figures are some of the content appropriate on business dashboards. === Performance Dashboards === Dashboards involve the combination of visual and functional features. This combination of features helps improve cognition and interpretation. A performance dashboard sits at the intersection of two powerful disciplines: business intelligence and performance management. Therefore, there are different users who could use these dashboards for different reasons. For example, a level of workers could look at monitoring inventory while those in more managerial roles can look at lagging measure. Then executives could utilize the dashboard to evaluate strategic performance against objectives. == Dashboards and scorecards == Balanced scorecards and dashboards have been linked together as if they were interchangeable. However, although both visually display critical information, the difference is in the format: Scorecards can open the quality of an operation while dashboards provide calculated direction. A balanced scorecard has what they called a "prescriptive" format. It should always contain these components: Perspectives – group Objectives – verb-noun phrases pulled from a strategy plan Measures – also called metric or key performance indicators (KPIs) Spotlight indicators – red, yellow, or green symbols that provide an at-a-glance view of a measure's performance. Each of these sections ensures that a Balanced Scorecard is essentially connected to the businesses critical strategic needs. The design of a dashboard is more loosely defined. Dashboards are usually a series of graphics, charts, gauges and other visual indicators that can be monitored and interpreted. Even when there is a strategic link, on a dashboard, it may not be noticed as such since objectives are not normally pre

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  Lenna

  Lenna (or Lena) is a standard test image used in the field of digital image processing, starting in 1973. It is a picture of the Swedish model Lena Forsén, shot by photographer Dwight Hooker and cropped from the centerfold of the November 1972 issue of Playboy magazine. Lenna has attracted controversy because of its subject matter. Starting in the mid-2010s, many journals have deemed it inappropriate and discouraged its use, while others have banned it from publication outright. Forsén herself has called for it to be retired, saying "It's time I retired from tech." The spelling "Lenna" came from the model's desire to encourage the proper pronunciation of her name. "I didn't want to be called Leena [English: ]," she explained. == History == Before Lenna, the first use of a Playboy magazine image to illustrate image processing algorithms was in 1961. Lawrence G. Roberts used two cropped six-bit grayscale facsimile scanned images from Playboy's July 1960 issue featuring Playmate Teddi Smith, in his master's thesis on image dithering at Massachusetts Institute of Technology. Lenna was originally intended for high resolution color image processing study. Its history was described in the May 2001 newsletter of the IEEE Professional Communication Society, in an article by Jamie Hutchinson: Alexander Sawchuk estimates that it was in June or July of 1973 when he, then an assistant professor of electrical engineering at the University of Southern California Signal and Image Processing Institute (SIPI), along with a graduate student and the SIPI lab manager, was hurriedly searching the lab for a good image to scan for a colleague's conference paper. They got tired of their stock of usual test images, dull stuff dating back to television standards work in the early 1960s. They wanted something glossy to ensure good output dynamic range, and they wanted a human face. Just then, somebody happened to walk in with a recent issue of Playboy. The engineers tore away the top third of the centerfold so they could wrap it around the drum of their Muirhead wirephoto scanner, which they had outfitted with analog-to-digital converters (one each for the red, green, and blue channels) and a Hewlett Packard 2100 minicomputer. The Muirhead had a fixed resolution of 100 lines per inch and the engineers wanted a 512×512 image, so they limited the scan to the top 5.12 inches of the picture, effectively cropping it at the subject's shoulders. The image's reach was limited in the 1970s and 80s, which is reflected in it initially only appearing in .org domains, but in July 1991, the image featured on the cover of Optical Engineering alongside Peppers, another popular test image. This drew the attention of Playboy to the potential copyright infringement. The peak of image hits on the internet was in 1995. The scan became one of the most used images in computer history. The use of the photo in electronic imaging has been described as "clearly one of the most important events in [its] history". The image spread to over 100 different domains, particularly .com and .edu. In a 1999 issue of IEEE Transactions on Image Processing "Lena" was used in three separate articles, and the picture continued to appear in scientific journals throughout the beginning of the 21st century. Lenna is so widely accepted in the image processing community that Forsén was a guest at the 50th annual Conference of the Society for Imaging Science and Technology (IS&T) in 1997. In 2015, Lena Forsén was also guest of honor at the banquet of IEEE ICIP 2015. After delivering a speech, she chaired the best paper award ceremony. To explain why the image became a standard in the field, David C. Munson, editor-in-chief of IEEE Transactions on Image Processing, stated that it was a good test image because of its detail, flat regions, shading, and texture. He also noted that "the Lena image is a picture of an attractive woman. It is not surprising that the (mostly male) image processing research community gravitated toward an image that they found attractive." While Playboy often cracks down on illegal uses of its material and did initially send a notice to the publisher of Optical Engineering about its unauthorized use in that publication, over time it has decided to overlook the wide use of Lena. Eileen Kent, VP of new media at Playboy, said, "We decided we should exploit this, because it is a phenomenon." == Criticism == The use of the image has produced controversy because Playboy is "seen (by some) as being degrading to women". In a 1999 essay on reasons for the male predominance in computer science, applied mathematician Dianne P. O'Leary wrote: Suggestive pictures used in lectures on image processing ... convey the message that the lecturer caters to the males only. For example, it is amazing that the "Lena" pin-up image is still used as an example in courses and published as a test image in journals today. A 2012 paper on compressed sensing used a photo of the model Fabio Lanzoni as a test image to draw attention to this issue. The use of the test image at the magnet school Thomas Jefferson High School for Science and Technology in Fairfax County, Virginia, provoked a guest editorial by a senior in The Washington Post in 2015 about its detrimental impact on aspiring female students in computer science. In 2017, the Journal of Modern Optics published an editorial titled "On alternatives to Lenna" suggesting three images (Pirate, Cameraman, and Peppers) that "are reasonably close to Lenna in feature space". In 2018, the Nature Nanotechnology journal announced that they would no longer consider articles using Lenna. In the same year SPIE, the publishers of Optical Engineering, also announced that they "strongly discourage" the use of Lenna, and would no longer consider new submissions containing the image "without convincing scientific justification for its use". They noted that aside from the copyright and ethical issues, that it was also no longer useful as a standard image: "In today's age of high-resolution digital image technology, it seems difficult to argue that a 512 × 512 image produced with a 1970s-era analog scanner is the best we have to offer as an image quality test standard". Forsén stated in the 2019 documentary film Losing Lena, "I retired from modeling a long time ago. It's time I retired from tech, too... Let's commit to losing me." The Institute of Electrical and Electronics Engineers (IEEE) announced that, starting April 1, 2024, it will no longer allow use of Lenna in its publications.

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  Social Media (Age-Restricted Users) Bill

  The Social Media (Age-Restricted Users) Bill is a member's bill by National Party Member of Parliament Catherine Wedd that seeks to ban children under the age of 16 years from accessing social media by forcing social media companies to implement age verification measures. It is modelled after the Australian government's Online Safety Amendment. In mid October 2025, the New Zealand Parliament confirmed plans to introduce the social media age restriction bill. == Background == In late November 2024, the Albanese government of Australia, with support from the opposition Coalition parties, passed the Online Safety Amendment creating a world-first age verification regime targeting social media platforms operating in the country. The ban targets several social media platforms including Facebook, Instagram, Kick, Reddit, Snapchat, Threads, TikTok, Twitch, X (formerly Twitter) and YouTube. These platforms were required to implement age verification systems and to remove under-age users by 10 December 2025, when the law change came into effect. == Draft provisions == The draft Social Media (Age-Restricted Users) Bill defines social media platforms as electronic platforms that enable social media interactions between two or more end-users, facilitates communication between multiple end-users and allows users to post content on the platform. The proposed bill requires social media companies to take action to prevent users under the age of 16 from creating accounts on their platforms. It also creates a framework for courts to impose fines on platforms that fail to take reasonable steps to prevent underaged users from accessing the platform. == Legislative history == === Draft legislation === On 6 May 2025, Wedd announced a private member's bill called the "Social Media (Age-Restricted Users) Bill" that would bar access to social media platforms for people under the age of 16 years. She said that she was motivated as the mother of four children to support families, parents and teachers' efforts to manage their children's online exposure and the passage of the Australian Online Safety Amendment legislation in December 2024. Since National's coalition partner ACT New Zealand had refused to support the bill, the Sixth National Government announce it as a member's bill rather than a government bill. Prime Minister Christopher Luxon has confirmed that National would seek cross-party support for the legislation. ACT MP and the Minister of Internal Affairs Brooke van Velden said that the Government would watch the implementation of the Australian social media age restriction policy. In October 2025, Wedd's bill was drawn from the parliamentary ballot. In addition, Labour Reuben Davidson drafted a similar member's bill that would hold social media providers responsible for restricting "harmful content" and imposed NZ$50,000 fines for non-compliance. In November 2025, Luxon reiterated his support for social media age restriction legislation and said the New Zealand government would introduce a bill in 2026 before the 2026 New Zealand general election. He also confirmed that Education Minister Erica Stanford was leading an investigation into what lessons could be learnt from the Australian legislation. At the request of ACT MP Parmjeet Parmar, Parliament's Education and Workforce Committee held an inquiry into a proposed social media ban in early October 2025. The committee was led by National MP Carl Bates and received 430 submissions from 400 groups and individuals. The committee also heard from 87 in-person submissions. On 10 December 2025, the committee made 12 recommendations including restricting social media access to persons under the age of 16, re-evaluating existing legislation such as the Films, Videos, and Publications Classification Act and the Harmful Digital Communications Act 2015, and regulating online platforms and Internet service providers. The ACT party released a dissenting view disagreeing with the need for a law restricting social media access to under-16 year olds. In mid-May 2026, the Government confirmed that work on the proposed bill to ban under-16 year olds from social media had been paused. The New Zealand Parliament held a debate on the proposed bill on 13 May following a select committee inquiry into the harms caused by social media platforms. While the opposition Labour Party has agreed to support the member's bill, the ACT and Green parties opposed the proposed bill on the grounds that the rules were easy to circumvent, that at-risk groups could become more isolated, and that social media also harmed other age groups. == Responses == === Academia and civil society === In late July 2025, the New Zealand Council for Civil Liberties (NZCCL) expressed concern that the proposed social media age restriction could infringe upon the New Zealand Bill of Rights Act 1990, the Privacy Act 2020 and the United Nations' Convention on the Rights of the Child. The NZCCL also questioned the practicality of age verification software, a social media age limit and whether it would fulfil its stated goal of combating online harm. In August 2025, University of Auckland criminologist and senior lecturer Claire Meehan expressed concern that the social media age restriction legislation would cut children from their friendship and support networks. She also said that children and young people were digital natives who could use VPNs to circumvent the ban. Similar sentiments were echoed by Victoria University of Wellington media and communications lecturer Alex Beattie and "Ocean Today" Instagram social media influencer "Charlie." In October 2025, New Zealand Initiative representative Dr Eric Crampton expressed concern that a social media age restriction would involve the introduction of digital IDs. He argued that a new law was unnecessary and said that parents could limit their children's exposure to social media via Google's Family Link and Apple's equivalent. Similarly, Institute of Economic Affairs public policy fellow Matthew Lesh and the British Free Speech Union expressed concerns that young people could use VPNs to circumvent a social media ban, citing the spike in VPN usage in the United Kingdom following the passage of the Online Safety Act 2023. The advocacy group B416's co-chair Anna Curzon advocated for a social media ban on underage users, stating that social media apps "are made to be addictive" and made it difficult for parents to relate with their children. In late November 2025, B416's co-founder Anna Mowbray expressed support for the Government's social media age restriction bill but expressed disappointment that Luxon had not timed his announcement with the launch of the group's campaign. Generation-Z Aotearoa co-founder Lola Fisher has called on the New Zealand Government to consult with young people on the development of the legislation. === Government agencies and departments === In early October 2025, Privacy Commissioner Michael Webster expressed concern that social media platforms requiring users to prove their age via digital IDs could raise privacy concerns. Webster suggested that age verification systems could relay on various documents including passports. He said that age estimation technologies had high error rates and that age inference technologies relied on data mining. === Political parties === In early May 2025, the National Party government expressed support for a social media age restriction legislation. By contrast, its coalition partner ACT has opposed such legislation. ACT leader David Seymour described the ban as hasty and unworkable since it did not involve parents. Meanwhile, New Zealand First leader Winston Peters expressed support for a social media age restriction but said the bill should be subject to a select committee inquiry. The opposition Labour Party leader Chris Hipkins has expressed interest in a social media age restriction legislation but emphasised the need for consensus. Meanwhile, Green Party co-leader Chlöe Swarbrick said she wanted to learn more about the bill but described it as simplistic. Fellow Greens co-leader Marama Davidson said that the proposed bill would punish children and young people for the harm caused by big tech platforms. === Tech companies === In early October 2025, representatives of TikTok and Meta Platforms cautioned against proposed social media ban on under-16 years olds. During a one-day parliamentary inquiry, Ella Woods-Joyce, TikTok's public policy lead for Australia and New Zealand, and Mia Garlick, Meta's regional director of policy, expressed concern that the social media age restriction could send children and young people to less regulated online spaces. Woods-Joyce highlighted TikTok's policy of closing down accounts belonging to users under the age of 13 years while Garlick highlighted Meta's policy of placing users under the age of 16 in private accounts by default. In early February 2026 Meta's vice president and global head of safety, Antigone Da

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  Data room

  Data rooms are secure spaces used for housing data, usually of a privileged or confidential nature. They can be physical data rooms, virtual data rooms (VDRs), or data centers. They are primarily used for a variety of corporate purposes, including data storage, document exchange, file sharing, financial transactions, and legal proceedings. Today, data rooms are central to workflows in mergers and acquisitions, venture capital, and corporate restructuring, increasingly utilizing artificial intelligence to securely manage and review large datasets. Historically, data rooms were strictly physical locations heavily guarded and monitored. Today, the vast majority of corporate data rooms are hosted virtually on secure cloud platforms, though physical rooms are still occasionally used for highly sensitive government or proprietary intelligence. == Physical Data Rooms == In mergers and acquisitions (M&A), the traditional data room genuinely consists of a physically secured and continually monitored room, normally in the vendor's offices or those of their legal counsel. Bidders and their advisers visit this room in order to inspect and report on various documents, legal contracts, and financial statements made available during the due diligence process. Historically, physical data rooms presented significant logistical challenges. Often, only one bidder at a time was allowed to enter to maintain document integrity and confidentiality. If new documents or new versions of documents were required, they had to be brought in by courier as hardcopies. Teams involved in large due diligence processes typically had to be flown in from many regions or countries and remain available throughout the process. Because these teams comprised a number of experts in different fields—such as legal counsel, forensic accountants, and industry specialists—the overall cost of keeping such groups on call near the physical data room was often extremely high. == Virtual Data Rooms (VDRs) == To address the costs and logistical bottlenecks of physical data rooms, virtual data rooms (VDRs) were developed to provide secure, online dissemination of confidential information. A VDR is essentially a secure cloud repository with strictly controlled access. Access is managed through secure log-ons supplied by the vendor or authority, which can be disabled at any time if a bidder withdraws from a transaction. Because much of the information released during corporate transactions is highly confidential, VDRs utilize digital rights management (DRM) to control information. Restrictions are applied to the viewers' ability to release data to third parties by disabling forwarding, copying, or printing capabilities. Modern VDRs also employ dynamic watermarking and detailed auditing capabilities. Detailed auditing is required for legal reasons so that a precise digital footprint is kept of who has viewed which version of each document, and for how long. Furthermore, modern VDR platforms are typically built to comply with stringent information security standards such as ISO 27001 and SOC 2. Transitioning from sequential physical data rooms to parallel virtual data rooms has been shown to significantly reduce the duration of M&A transactions while allowing sellers to field multiple bidders simultaneously. == Key Applications == Data rooms are commonly used by legal, accounting, investment banking, and private equity firms. Primary applications include: Mergers and Acquisitions (M&A): VDRs are central to the sell-side M&A process. After potential buyers sign a Non-Disclosure Agreement (NDA) and review a Confidential Information Memorandum (CIM), they are granted data room access to perform deep financial due diligence, such as Quality of Earnings (QoE) analysis and legal liability assessments. Venture Capital and Startups: Startups use data rooms as a centralized location for key operational data, capitalization tables, and financial projections to streamline due diligence for angel investors and venture capital firms during fundraising rounds. Initial Public Offerings (IPOs): Taking a company public requires intense regulatory scrutiny. Data rooms are used to securely share company histories and financial audits with investment bankers, legal teams, and regulatory bodies. Corporate Restructuring and Insolvency: During bankruptcies or corporate carve-outs, data rooms are used to organize outstanding debt profiles, creditor agreements, and operational liabilities. == Emerging Technologies == In recent years, the management of virtual data rooms has increasingly incorporated Artificial Intelligence (AI) and Machine Learning (ML). Generative AI and Natural Language Processing (NLP) tools are now integrated into VDRs to automatically index thousands of documents, perform auto-redaction of personally identifiable information (PII), and assist buy-side analysts in identifying hidden liabilities within unstructured text data during the due diligence phase. Modern AI algorithms can extract line items from financial statements to instantly populate structured databases.

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  Campus network

  A campus network, campus area network, corporate area network or CAN is a computer network made up of an interconnection of local area networks (LANs) within a limited geographical area. The networking equipments (switches, routers) and transmission media (optical fiber, copper plant, Cat5 cabling etc.) are almost entirely owned by the campus tenant / owner: an enterprise, university, government etc. A campus area network is larger than a local area network but smaller than a metropolitan area network (MAN) or wide area network (WAN). == University campuses == College or university campus area networks often interconnect a variety of buildings, including administrative buildings, academic buildings, laboratories, university libraries, or student centers, residence halls, gymnasiums, and other outlying structures, like conference centers, technology centers, and training institutes. Early examples include the Stanford University Network at Stanford University, Project Athena at MIT, and the Andrew Project at Carnegie Mellon University. == Corporate campuses == Much like a university campus network, a corporate campus network serves to connect buildings. Examples of such are the networks at Googleplex and Microsoft's campus. Campus networks are normally interconnected with high speed Ethernet links operating over optical fiber such as gigabit Ethernet and 10 Gigabit Ethernet. == Area range == The range of CAN is 1 to 5 km (1 to 3 mi). If two buildings have the same domain and they are connected with a network, then it will be considered as CAN only. Though the CAN is mainly used for corporate campuses so the link will be high speed.

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  Artificial reproduction

  Artificial reproduction is the re-creation of life brought about by means other than natural ones. It is new life built by human plans and projects. Examples include artificial selection, artificial insemination, in vitro fertilization, artificial womb, artificial cloning, and kinematic replication. Artificial reproduction is one aspect of artificial life. Artificial reproduction can be categorized into one of two classes according to its capacity to be self-sufficient: non-assisted reproductive technology and assisted reproductive technology. Cutting plants' stems and placing them in compost is a form of assisted artificial reproduction, xenobots are an example of a more autonomous type of reproduction, while the artificial womb presented in the movie the Matrix illustrates a non assisted hypothetical technology. The idea of artificial reproduction has led to various technologies. == Theology == Humans have aspired to create life since immemorial times. Most theologies and religions have conceived this possibility as exclusive of deities. Christian religions consider the possibility of artificial reproduction, in most cases, as heretical and sinful. == Philosophy == Although ancient Greek philosophy raised the concept that man could imitate the creative capacity of nature, classic Greeks thought that if possible, human beings would reproduce things as nature does, and vice versa, nature would do the things that man does in the same way. Aristotle, for example, wrote that if nature made tables, it would make them just as men do. In other words, Aristotle said that if nature were to create a table, such table will look like a human-made table. Correspondingly, Descartes envisioned the human body, and nature, as a machine. Cartesian philosophy does not stop seeing a perfect mirror between nature and the artificial. However, Kant revolutionized this old idea by criticizing such naturalism. Kant pedagogically wrote: "Reason, in order to be taught by nature, must approach nature with its principles in one hand, according to which the agreement among appearances can count as laws, and, in the other hand, the experiment thought out in accord with these principles—in order to be instructed by nature not like a pupil, who has recited to him whatever the teacher wants to say, but like an appointed judge who compels witnesses to answer the questions he puts to them.". Humans are not instructed by nature but rather use nature as raw material to invent. Humans find alternatives to the natural restrictions imposed by natural laws thus, nature is not necessarily mirrored. In accordance with Kant (and contrary to what Aristotle thought) Karl Marx, Alfred Whitehead, Jaques Derrida and Juan David García Bacca noticed that nature is incapable of reproducing tables; or airplanes, or submarines, or computers. If nature tried to create airplanes, it would produce birds. If nature tried to create submarines, it would get fishes. If nature tried to create computers, brains would grow. And if nature tried to create man, modern man, monkeys will be evolved. According to Whitehead, if we look for something natural in artificial life, in the most elaborate cases, if anything, only atoms remain natural. Juan David Garcia Bacca summarized, “It will not come out from wood, it will not be born, a galley; from clay, a vessel; from linen, a dress; from iron, a lever,...From natural, artificial. In the artificial, the natural is reduced to a simple raw material, even though it is perfectly specified with natural specification. The artificial is the real, positive, and original negation of the natural: of species, of genus and of essence. Thus, its ontology is superior to natural ontology. And for this very reason Marx did not attach any importance to Darwin, whose evolutionism is confined to the natural order: to changes, at most, from variety to variety, from species to species... natural. For the same reason, nature has no dialectics, even though continuous evolution and selection can occur. The dialectic cannot emerge from the natural, for deeper reasons than, using today's terms, from a bird, an airplane cannot emerge; from fish, a submarine; from ears, a telephone; from eyes, a television; from a brain, a digital computer; from feet, a car; from hands, an engine; from Euclid, Descartes; from Aristotle, Newton; from Plato, Marx.” According to García Bacca, the major difference between natural causes and artificial causes is that nature does not have plans and projects, while humans design things following plans and projects. In contrast, other influential authors such as Michael Behe have depicted the concept and promoted the idea of intelligent design, a notion that has aroused several doubts and heated controversies, as it reframe natural causes in accordance with a natural plan. Previous ideas that have also provided a positive 'sense' to natural reproduction, are orthogenesis, syntropy, orgone and morphic resonance, among others. Although, these ideas have been historically marginalized and often called pseudoscience, recently Bio-semioticians are reconsidering some of them under symbolic approaches. Current metaphysics of science actually recognizes that the artificial ways of reproduction are diverse from nature, i.e., unnatural, anti-natural or supernatural. Because Biosemiotics does not focus on the function of life but on its meaning, it has a better understanding of the artificial than classic biology. == Science == Biology, being the study of cellular life, addresses reproduction in terms of growth and cellular division (i.e., binary fission, mitosis and meiosis); however, the science of artificial reproduction is not restricted by the mirroring of these natural processes.The science of artificial reproduction is actually transcending the natural forms, and natural rules, of reproduction. For example, xenobots have redefined the classical conception of reproduction. Although xenobots are made of eukariotic cells they do not reproduce by mitosis, but rather by kinematic replication. Such constructive replication does not involve growing but rather building. == Assisted reproductive technologies == Assisted reproductive technology (ART)'s purpose is to assist the development of a human embryo, commonly because of medical concerns due to fertility limitations. == Non-assisted reproductive technologies == Non-assisted reproductive technologies (NART) could have medical motivations but are mostly driven by a wider heterotopic ambition. Although, NARTs are initially designed by humans, they are programed to become independent of humans to a relative or absolute extent. James Lovelock proposed that such novelties could overcome humans. === Artificial cloning === Cloning is the cellular reproductive processes where two or more genetically identical organisms are created, either by natural or artificial means. Artificial cloning normally involves editing the genetic code, somatic cell nuclear transfer and 3D bioprinting. === Non-assisted artificial womb === A non-assisted artificial womb or artificial uterus is a device that allow for ectogenesis or extracorporeal pregnancy by growing an embryonic form outside the body of an organism (that would normally carry the embryo to term) without any human assistance. The aspect of non-assistance is the key distinction between the current artificial womb technology (AWT) in modern medical research, which still relies on human assistance. With this non-assisted hypothetical technology, a zygote or stem cells are used to create an embryo that is then incubated and monitored by artificial intelligence (AI) within a chamber composed of biocompatible material. The AI maintains the necessary conditions for the embryo to develop and thrive, proceeding to mimic organic labor and childbirth in order to best help the embryo adjust to the outside world. Ectogenesis—gestation, depicted in the science fiction movie The Matrix, is a fast approaching reality. This type of innovation presupposes that vertebrate wombs are not the only way for bearing humans or other similar forms of life. === Kinematic replication === Self-replication without binary fission, meiosis, mitosis (or any other form of cellular reproduction that involves division and growing) can be achieved. Xenobots are an example of kinematic replication. They are biobots, named after the African clawed frog (Xenopus laevis). Xenobots are cellular life forms designed by using artificial intelligence to build more of themselves by combining frog cells in a liquid medium. The term kinematic replication is usually reserved for biomolecules (e.g. DNA, RNA, prions, etc.) and artificially designed cellular forms (e.g. xenobots). === Machine constructive replication === Machine constructive replication mimics human traditional manufacturing but is entirely self-automated. Such constructive replication is a more general form of kinematic replication, which does not necessarily

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  NYSERNet

  NYSERNet, Inc. (New York State Education and Research Network), is a non-profit Internet service provider in New York State. It mainly provides Internet access to universities, colleges, museums, health care facilities, primary and secondary schools, and research institutions. == History == NYSERNet was founded in 1986 in Troy, New York. Its founders compared NYSERNet's network with the Erie Canal and considered it the next step in two centuries to draw the country together. NYSERNet's network reaches from Buffalo to New York City. Completed in 1987, it was the first statewide regional IP network in the United States.[1] Initial speed of 56 kbps was upgraded to T1 in 1989 and T3 in 1994. It was the original assignee of AS174 according to RFC1117. This ASN is used today by Cogent Communications for their global network.

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  Cryptographic Service Provider

  A cryptographic service provider (CSP) is a package that "provides a concrete implementation of certain cryptographic services." A CSP offers operations and protocols to support a variety of use cases. The cryptographic application programming interface (API) provided by the CSP provides common solutions for different platforms, for example hardware and cloud services. == Microsoft Windows == In Microsoft Windows, a Cryptographic Service Provider is a software library that implements the Microsoft CryptoAPI (CAPI). CSPs implement encoding and decoding functions, which computer application programs may use, for example, to implement strong user authentication or for secure email. CSPs are independent modules that can be used by different applications. A user program calls CryptoAPI functions and these are redirected to CSPs functions. Since CSPs are responsible for implementing cryptographic algorithms and standards, applications do not need to be concerned about security details. Furthermore, each application can define which CSP it is going to use on its calls to CryptoAPI. In fact, all cryptographic activity is implemented in CSPs. CryptoAPI only works as a bridge between the application and the CSP. CSPs are implemented basically as a special type of DLL with special restrictions on loading and use. Every CSP must be digitally signed by Microsoft and the signature is verified when Windows loads the CSP. In addition, after being loaded, Windows periodically re-scans the CSP to detect tampering, either by malicious software such as computer viruses or by the user him/herself trying to circumvent restrictions (for example on cryptographic key length) that might be built into the CSP's code. To obtain a signature, non-Microsoft CSP developers must supply paperwork to Microsoft promising to obey various legal restrictions and giving valid contact information. As of circa 2000, Microsoft did not charge any fees to supply these signatures. For development and testing purposes, a CSP developer can configure Windows to recognize the developer's own signatures instead of Microsoft's, but this is a somewhat complex and obscure operation unsuitable for nontechnical end users. The CAPI/CSP architecture had its origins in the era of restrictive US government controls on the export of cryptography. Microsoft's default or "base" CSP then included with Windows was limited to 512-bit RSA public-key cryptography and 40-bit symmetric cryptography, the maximum key lengths permitted in exportable mass market software at the time. CSPs implementing stronger cryptography were available only to U.S. residents, unless the CSPs themselves had received U.S. government export approval. The system of requiring CSPs to be signed only on presentation of completed paperwork was intended to prevent the easy spread of unauthorized CSPs implemented by anonymous or foreign developers. As such, it was presented as a concession made by Microsoft to the government, in order to get export approval for the CAPI itself. After the Bernstein v. United States court decision establishing computer source code as protected free speech and the transfer of cryptographic regulatory authority from the U.S. State Department to the more pro-export Commerce Department, the restrictions on key lengths were dropped, and the CSPs shipped with Windows now include full-strength cryptography. The main use of third-party CSPs is to interface with external cryptography hardware such as hardware security modules (HSM) or smart cards. === Smart Card CSP === These cryptographic functions can be realized by a smart card, thus the Smart Card CSP is the Microsoft way of a PKCS#11. Microsoft Windows is identifying the correct Smart Card CSP, which have to be used, analyzing the answer to reset (ATR) of the smart card, which is registered in the Windows Registry. Installing a new CSP, all ATRs of the supported smart cards are enlisted in the registry. === Use of CSP in MS Office password protection === Cryptographic service providers can be used for encryption of Word, Excel, and PowerPoint documents starting from Microsoft Office XP. A standard encryption algorithm with a 40-bit key is used by default, but enabling a CSP enhances key length and thus makes decryption process more continuous. This only applies to passwords that are required to open document because this password type is the only one that encrypts a password-protected document.

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  Reverse proxy

  In computer networks, a reverse proxy or surrogate server is a proxy server that appears to any client to be an ordinary web server, but in reality merely acts as an intermediary that forwards the client's requests to one or more ordinary web servers. Reverse proxies help increase scalability, performance, resilience, and security, but they also carry a number of risks. Companies that run web servers often set up reverse proxies to facilitate the communication between an Internet user's browser and the web servers. An important advantage of doing so is that the web servers can be hidden behind a firewall on a company-internal network, and only the reverse proxy needs to be directly exposed to the Internet. Reverse proxy servers are implemented in popular open-source web servers. Dedicated reverse proxy servers are used by some of the biggest websites on the Internet. A reverse proxy is capable of tracking IP addresses of requests that are relayed through it as well as reading and/or modifying any non-encrypted traffic. However, this implies that anyone who has compromised the server could do so as well. Reverse proxies differ from forward proxies, which are used when the client is restricted to a private, internal network and asks a forward proxy to retrieve resources from the public Internet. == Uses == Large websites and content delivery networks use reverse proxies, together with other techniques, to balance the load between internal servers. Reverse proxies can keep a cache of static content, which further reduces the load on these internal servers and the internal network. It is also common for reverse proxies to add features such as compression or TLS encryption to the communication channel between the client and the reverse proxy. Reverse proxies can inspect HTTP headers, which, for example, allows them to present a single IP address to the Internet while relaying requests to different internal servers based on the URL of the HTTP request. Reverse proxies can hide the existence and characteristics of origin servers. This can make it more difficult to determine the actual location of the origin server / website and, for instance, more challenging to initiate legal action such as takedowns or block access to the website, as the IP address of the website may not be immediately apparent. Additionally, the reverse proxy may be located in a different jurisdiction with different legal requirements, further complicating the takedown process. Application firewall features can protect against common web-based attacks, like a denial-of-service attack (DoS) or distributed denial-of-service attacks (DDoS). Without a reverse proxy, removing malware or initiating takedowns (while simultaneously dealing with the attack) on one's own site, for example, can be difficult. In the case of secure websites, a web server may not perform TLS encryption itself, but instead offload the task to a reverse proxy that may be equipped with TLS acceleration hardware. (See TLS termination proxy.) A reverse proxy can distribute the load from incoming requests to several servers, with each server supporting its own application area. In the case of reverse proxying web servers, the reverse proxy may have to rewrite the URL in each incoming request in order to match the relevant internal location of the requested resource. A reverse proxy can reduce load on its origin servers by caching static content and dynamic content, known as web acceleration. Proxy caches of this sort can often satisfy a considerable number of website requests, greatly reducing the load on the origin server(s). A reverse proxy can optimize content by compressing it in order to speed up loading times. In a technique named "spoon-feeding", a dynamically generated page can be produced in its entirety and served to the reverse proxy, which can feed the page to the client as the connection allows. The program that generates the page need not remain open, thus releasing server resources during the possibly extended time the client requires to complete the transfer. Reverse proxies can operate wherever multiple web-servers must be accessible via a single public IP address. The web servers listen on different ports in the same machine, with the same local IP address or, possibly, on different machines with different local IP addresses. The reverse proxy analyzes each incoming request and delivers it to the right server within the local area network. Reverse proxies can perform A/B testing and multivariate testing without requiring application code to handle the logic of which version is served to a client. A reverse proxy can add access authentication to a web server that does not have any authentication. == Risks == When the transit traffic is encrypted and the reverse proxy needs to filter/cache/compress or otherwise modify or improve the traffic, the proxy first must decrypt and re-encrypt communications. This requires the proxy to possess the TLS certificate and its corresponding private key, extending the number of systems that can have access to non-encrypted data and making it a more valuable target for attackers. The vast majority of external data breaches happen either when hackers succeed in abusing an existing reverse proxy that was intentionally deployed by an organization, or when hackers succeed in converting an existing Internet-facing server into a reverse proxy server. Compromised or converted systems allow external attackers to specify where they want their attacks proxied to, enabling their access to internal networks and systems. Applications that were developed for the internal use of a company are not typically hardened to public standards and are not necessarily designed to withstand all hacking attempts. When an organization allows external access to such internal applications via a reverse proxy, they might unintentionally increase their own attack surface and invite hackers. If a reverse proxy is not configured to filter attacks or it does not receive daily updates to keep its attack signature database up to date, a zero-day vulnerability can pass through unfiltered, enabling attackers to gain control of the system(s) that are behind the reverse proxy server. Giving the reverse proxy of a third party access to private keys (for caching or optimizing content) places the entire triad of confidentiality, integrity and availability in the hands of the third party who operates the proxy. A reverse proxy is a single point of failure for the back-end services it fronts: an outage caused by misconfiguration, a denial-of-service attack, or a software fault can make every fronted service unreachable to outside clients, even when the back-end services themselves remain healthy. For example, a 2020 outage at Cloudflare briefly took down major sites and services that relied on its reverse-proxy edge, including Discord.

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  Biopython

  Biopython is an open-source collection of non-commercial Python modules for computational biology and bioinformatics. It makes robust and well-tested code easily accessible to researchers. Python is an object-oriented programming language and is a suitable choice for automation of common tasks. The availability of reusable libraries saves development time and lets researchers focus on addressing scientific questions. Biopython is constantly updated and maintained by a large team of volunteers across the globe. Biopython contains parsers for diverse bioinformatic sequence, alignment, and structure formats. Sequence formats include FASTA, FASTQ, GenBank, and EMBL. Alignment formats include Clustal, BLAST, PHYLIP, and NEXUS. Structural formats include the PDB, which contains the 3D atomic coordinates of the macromolecules. It has provisions to access information from biological databases like NCBI, Expasy, PBD, and BioSQL. This can be used in scripts or incorporated into their software. Biopython contains a standard sequence class, sequence alignment, and motif analysis tools. It also has clustering algorithms, a module for structural biology, and a module for phylogenetics analysis. == History == The development of Biopython began in 1999, and it was first released in July 2000. First "semi-complete" and "semi-stable" release was done in March 2001 and December 2002 respectively. It was developed during a similar time frame and with analogous goals to other projects that added bioinformatics capabilities to their respective programming languages, including BioPerl, BioRuby and BioJava. Early developers on the project included Jeff Chang, Andrew Dalke and Brad Chapman, though over 100 people have made contributions to date. In 2007, a similar Python project, namely PyCogent, was established. The initial scope of Biopython involved accessing, indexing and processing biological sequence files. The retrieved data from common biological databases will then be parsed into a python data structure. While this is still a major focus, over the following years added modules have extended its functionality to cover additional areas of biology. The key challenge in the design of parsers for bioinformatics file formats is the frequency at which the data formats change. This is due to inadequate curation of the structure of the data, and changes in the database contents. This problem is overcome by the application of a standard event-oriented parser design (see Key features and examples). As of version 1.77, Biopython no longer supports Python 2. The current stable release of Biopython version 1.85 was released on 15 January 2025. It only supports Python 3 and the recent releases of Biopython require NumPy (and not Numeric). == Design == Wherever possible, Biopython follows the conventions used by the Python programming language to make it easier for users familiar with Python. For example, Seq and SeqRecord objects can be manipulated via slicing, in a manner similar to Python's strings and lists. It is also designed to be functionally similar to other Bio projects, such as BioPerl. It is organized into modular sub-packages, e.g., Bio.Seq, Bio.Align, Bio.PDB, Bio.Entrez each of them useful in a different bioinformatics domain. It used principles, like encapsulation and polymorphism, notably in classes Seq, SeqRecord, and Bio.PDB.Structure. It can also interoperate with other Python tools (Pandas, Matplotlib and SciPy). Biopython can read and write most common file formats for each of its functional areas, and its license is permissive and compatible with most other software licenses, which allows Biopython to be used in a variety of software projects. == Requirements == Biopython is currently supported and tested with the following Python implementations: Python 3 or PyPy3 NumPy == Key features and examples == === Input and output === Biopython can read and write to a number of common formats. When reading files, descriptive information in the file is used to populate the members of Biopython classes, such as SeqRecord. This allows records of one file format to be converted into others. Very large sequence files can exceed a computer's memory resources, so Biopython provides various options for accessing records in large files. They can be loaded entirely into memory in Python data structures, such as lists or dictionaries, providing fast access at the cost of memory usage. Alternatively, the files can be read from disk as needed, with slower performance but lower memory requirements. === Sequences === A core concept in Biopython is the biological sequence, and this is represented by the Seq class. A Biopython Seq object is similar to a Python string in many respects: it supports the Python slice notation, can be concatenated with other sequences and is immutable. This object includes both general string-like and biological sequence-specific methods. It is best to store information about the biological type (DNA, RNA, protein) separately from the sequence, rather than using an explicit alphabet argument. === Sequence annotation === The SeqRecord class describes sequences, along with information such as name, description and features in the form of SeqFeature objects. Each SeqFeature object specifies the type of the feature and its location. Feature types can be ‘gene’, ‘CDS’ (coding sequence), ‘repeat_region’, ‘mobile_element’ or others, and the position of features in the sequence can be exact or approximate. === Accessing online databases === Through the Bio.Entrez module, users of Biopython can download biological data from NCBI databases. Each of the functions provided by the Entrez search engine is available through functions in this module, including searching for and downloading records. === Phylogeny === The Bio.Phylo module provides tools for working with and visualising phylogenetic trees. A variety of file formats are supported for reading and writing, including Newick, NEXUS and phyloXML. Common tree manipulations and traversals are supported via the Tree and Clade objects. Examples include converting and collating tree files, extracting subsets from a tree, changing a tree's root, and analysing branch features such as length or score. Rooted trees can be drawn in ASCII or using matplotlib (see Figure 1), and the Graphviz library can be used to create unrooted layouts (see Figure 2). === Genome diagrams === The GenomeDiagram module provides methods of visualising sequences within Biopython. Sequences can be drawn in a linear or circular form (see Figure 3), and many output formats are supported, including PDF and PNG. Diagrams are created by making tracks and then adding sequence features to those tracks. By looping over a sequence's features and using their attributes to decide if and how they are added to the diagram's tracks, one can exercise much control over the appearance of the final diagram. Cross-links can be drawn between different tracks, allowing one to compare multiple sequences in a single diagram. === Macromolecular structure === The Bio.PDB module can load molecular structures from PDB and mmCIF files, and was added to Biopython in 2003. The Structure object is central to this module, and it organises macromolecular structure in a hierarchical fashion: Structure objects contain Model objects which contain Chain objects which contain Residue objects which contain Atom objects. Disordered residues and atoms get their own classes, DisorderedResidue and DisorderedAtom, that describe their uncertain positions. Using Bio.PDB, one can navigate through individual components of a macromolecular structure file, such as examining each atom in a protein. Common analyses can be carried out, such as measuring distances or angles, comparing residues and calculating residue depth. === Population genetics === The Bio.PopGen module adds support to Biopython for Genepop, a software package for statistical analysis of population genetics. This allows for analyses of Hardy–Weinberg equilibrium, linkage disequilibrium and other features of a population's allele frequencies. This module can also carry out population genetic simulations using coalescent theory with the fastsimcoal2 program. === Wrappers for command line tools === Biopython previously included command-line wrappers for tools such as BLAST, Clustal, EMBOSS, and SAMtools. This option allowed users to run external tool commands from within the code using specialized Biopython classes. However, Bio.Application modules and their wrappers have deprecated and will be removed in future Biopython releases. The main reason for this is the high maintenance burden of updating them with the evolving external tools. The recommended approach is to directly construct and execute command-line tool commands using Python’s built-in subprocess module. This method provides flexibility and removes the dependency on the Biopython wrappers. subprocess is a native Python module useful for running ext

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  European Grid Infrastructure

  EGI (originally an initialism for European Grid Infrastructure) is a federation of computing and storage resource providers that deliver advanced computing and data analytics services for research and innovation. The Federation is governed by its participants represented in the EGI Council and coordinated by the EGI Foundation. As of 2024, the EGI Federation supports 160 scientific communities worldwide and over 95,000 users in their intensive data analysis. The most significant scientific communities supported by EGI in 2022 were Medical and Health Sciences, High Energy Physics, and Engineering and Technology. The EGI Federation provideds services through over 150 data centres, of which 25 are cloud sites, in 43 countries and 64 Research Infrastructures (4 of which are members of the Federation). == Name == Originally, EGI stood for European Grid Infrastructure. This reflected its focus on providing access to high-throughput computing resources across Europe using Grid computing techniques. However, as EGI's service offerings expanded beyond traditional grid computing, particularly with the incorporation of federated cloud services, the original meaning of the acronym became less accurate. To emphasise the broader scope of EGI's services and avoid any confusion associated with the outdated term "grid," it is recommended to refer to EGI simply as EGI. == Structure == === EGI Federation === The EGI Federation delivers a scalable digital research infrastructure (e-infrastructure), empowering tens of thousands of researchers across diverse scientific disciplines. Through the EGI Federation, researchers gain access to advanced computing and data analytics capabilities, including large-scale data analysis, while benefiting from the collaborative efforts of hundreds of service providers from both public and private sectors, consolidating resources from Europe and beyond. Overall, the EGI Federation offers a range of services, encompassing distributed high-throughput computing and cloud computing, storage and data management capabilities, co-development of new solutions, expert support, and comprehensive training opportunities. This ecosystem propels collaboration, scientific progress and innovation. === EGI Foundation === The EGI Foundation is the coordinating body of the EGI Federation. It was established in 2010 with headquarters in Amsterdam, Netherlands. The Foundation coordinates the research and innovation efforts of its members, spanning technical areas critical to data-intensive science, including large-scale data processing and analysis, distributed Artificial Intelligence/Machine Learning, federated Identity and access management and the application of digital twins for research. The day-to-day running of the EGI Foundation is supervised by the Executive Board. The board’s members work closely with the EGI Director on operational, technical and financial issues. The Executive Board’s members are appointed by the EGI Council for a two-year term. === EGI Council === The EGI Council is responsible for defining the strategic direction of the EGI Federation. The Council acts as the senior decision-making and supervisory authority of the EGI Foundation, with a mandate to define the strategic direction of the entire EGI ecosystem. === EGI Services === EGI offers a suite of services to support data-intensive research. These services include compute resources, orchestration tools, storage and data management solutions, training programmes, security and identity services, and applications. Compute resources encompass cloud compute, cloud container compute, high-throughput compute, and software distribution. Orchestration tools include the Workload Manager and infrastructure manager. Storage and data management solutions include online storage, data transfer, and DataHub. Training programmes cover FitSM, ISO 27001, and general training infrastructure. EGI Check-in and Secrets Store are key security and identity services, while applications such as Notebooks and Replay enhance research productivity. In addition to services for Research, EGI also provides services for Federation and Business. Services for Federation are designed to help resource providers and user communities collaborate and share resources. EGI also offers a range of services to support businesses in their digital transformation. Through the EGI Digital Innovation Hub (EGI DIH), companies can access advanced computing resources, networking, funding and training opportunities, collaborate with research institutions, and test solutions before investing. == History == In 2002, the first large-scale experimental facility was successfully demonstrated by the DataGrid project under the lead of CERN with tens of technical architects from the major High Energy Physics institutes in the world. For the first time, distributed computing was applied to data-intensive processing. It aimed at developing a large-scale computational grid to facilitate distributed data-intensive scientific computing across High Energy Physics, Earth Observation, and Biology science applications. On 28 February 2003, the first software release of LCG-MW was published. gLite, the Lightweight Middleware for Grid Computing and LCG, Large Hadron Collider Computing Grid, are the cornerstone of the Worldwide LHC Computing Grid, which expanded over time towards the EGI Federation. 2004 marks the year of the first pilot infrastructure, seeing the participation of CERN and data centres in the United Kingdom, Spain, Germany, the Netherlands, France, Canada, Russia, Bulgaria, the Asia-Pacific region and Switzerland. Over the years, the infrastructure has grown into a federation of 128 data centres and 25 cloud providers serving more than 95,000 users worldwide. In 2004, the first data processing tasks started being formally recorded in a central accounting system. The EGI Accounting Portal provides the accounting data for Compute, Storage and Data services gathered from the data centres of the EGI Federation. A few years later, in 2010, EGI was established as the coordinating body of the EGI Federation to build an integrated pan-European infrastructure to support European research communities primarily. In the same year, EGI launched the flagship project EGI Inspire. That project brought together European organisations to establish a sustainable European Grid Infrastructure for large-scale data analysis. The success of the project was due to the adoption of a distributed computing model to solve big data problems. Moreover, EGI-Inspire harmonised operational policies across its federation of affiliated data centres and cloud service providers worldwide, integrating e-infrastructures from 57 countries. The EGI Federation was the first to apply federation to cloud provisioning, opening a new avenue in large-scale interactive data analysis. In 2015, within EGI Engage, opening a new avenue in large-scale interactive data analysis. The EGI Federated Cloud is an IaaS-type cloud, incorporating academic and private clouds and virtualised resources built using open standards. Its development is driven by the needs of the scientific community, resulting in a novel research e-infrastructure that relies on well-established federated operational services, making EGI a dependable resource for scientific endeavours. In 2015, EGI, EUDAT, GÉANT, LIBER and OpenAIRE published a position paper on a 'European Open Science Cloud for Research'. With the EOSC-hub project in 2016, EGI started contributing in practice to shaping the services for the EOSC. The work continued with a series of projects, like EOSC Enhance, EOSC Life and EOSC Synergy. With EGI-ACE and its contribution to EOSC Future, EGI has continued developing the EOSC Core. In early 2024, EGI started providing services to the EOSC EU Node, and with EOSC Beyond it will provide new EOSC Core capabilities and pilot additional national and thematic nodes. In October 2024, EUDAT, GÉANT, OpenAIRE, PRACE and EGI signed a Memorandum of Understanding establishing the European e-Infrastructures Assembly. This collaboration will bolster the position and promote the services of e-Infrastructures, empowering researchers across Europe to drive innovation and advance scientific discovery.

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  Clustered file system

  A clustered file system (CFS) is a file system which is shared by being simultaneously mounted on multiple servers. There are several approaches to clustering, most of which do not employ a clustered file system (only direct attached storage for each node). Clustered file systems can provide features like location-independent addressing and redundancy which improve reliability or reduce the complexity of the other parts of the cluster. Parallel file systems are a type of clustered file system that spread data across multiple storage nodes, usually for redundancy or performance. == Shared-disk file system == A shared-disk file system uses a storage area network (SAN) to allow multiple computers to gain direct disk access at the block level. Access control and translation from file-level operations that applications use to block-level operations used by the SAN must take place on the client node. The most common type of clustered file system, the shared-disk file system – by adding mechanisms for concurrency control – provides a consistent and serializable view of the file system, avoiding corruption and unintended data loss even when multiple clients try to access the same files at the same time. Shared-disk file-systems commonly employ some sort of fencing mechanism to prevent data corruption in case of node failures, because an unfenced device can cause data corruption if it loses communication with its sister nodes and tries to access the same information other nodes are accessing. The underlying storage area network may use any of a number of block-level protocols, including SCSI, iSCSI, HyperSCSI, ATA over Ethernet (AoE), Fibre Channel, network block device, and InfiniBand. There are different architectural approaches to a shared-disk filesystem. Some distribute file information across all the servers in a cluster (fully distributed). === Examples === == Distributed file systems == Distributed file systems do not share block level access to the same storage but use a network protocol. These are commonly known as network file systems, even though they are not the only file systems that use the network to send data. Distributed file systems can restrict access to the file system depending on access lists or capabilities on both the servers and the clients, depending on how the protocol is designed. The difference between a distributed file system and a distributed data store is that a distributed file system allows files to be accessed using the same interfaces and semantics as local files – for example, mounting/unmounting, listing directories, read/write at byte boundaries, system's native permission model. Distributed data stores, by contrast, require using a different API or library and have different semantics (most often those of a database). === Design goals === Distributed file systems may aim for "transparency" in a number of aspects. That is, they aim to be "invisible" to client programs, which "see" a system which is similar to a local file system. Behind the scenes, the distributed file system handles locating files, transporting data, and potentially providing other features listed below. Access transparency: clients are unaware that files are distributed and can access them in the same way as local files are accessed. Location transparency: a consistent namespace exists encompassing local as well as remote files. The name of a file does not give its location. Concurrency transparency: all clients have the same view of the state of the file system. This means that if one process is modifying a file, any other processes on the same system or remote systems that are accessing the files will see the modifications in a coherent manner. Failure transparency: the client and client programs should operate correctly after a server failure. Heterogeneity: file service should be provided across different hardware and operating system platforms. Scalability: the file system should work well in small environments (1 machine, a dozen machines) and also scale gracefully to bigger ones (hundreds through tens of thousands of systems). Replication transparency: Clients should not have to be aware of the file replication performed across multiple servers to support scalability. Migration transparency: files should be able to move between different servers without the client's knowledge. === History === The Incompatible Timesharing System used virtual devices for transparent inter-machine file system access in the 1960s. More file servers were developed in the 1970s. In 1976, Digital Equipment Corporation created the File Access Listener (FAL), an implementation of the Data Access Protocol as part of DECnet Phase II which became the first widely used network file system. In 1984, Sun Microsystems created the file system called "Network File System" (NFS) which became the first widely used Internet Protocol based network file system. Other notable network file systems are Andrew File System (AFS), Apple Filing Protocol (AFP), NetWare Core Protocol (NCP), and Server Message Block (SMB) which is also known as Common Internet File System (CIFS). In 1986, IBM announced client and server support for Distributed Data Management Architecture (DDM) for the System/36, System/38, and IBM mainframe computers running CICS. This was followed by the support for IBM Personal Computer, AS/400, IBM mainframe computers under the MVS and VSE operating systems, and FlexOS. DDM also became the foundation for Distributed Relational Database Architecture, also known as DRDA. There are many peer-to-peer network protocols for open-source distributed file systems for cloud or closed-source clustered file systems, e. g.: 9P, AFS, Coda, CIFS/SMB, DCE/DFS, WekaFS, Lustre, PanFS, Google File System, Mnet, Chord Project. === Examples === == Network-attached storage == Network-attached storage (NAS) provides both storage and a file system, like a shared disk file system on top of a storage area network (SAN). NAS typically uses file-based protocols (as opposed to block-based protocols a SAN would use) such as NFS (popular on UNIX systems), SMB/CIFS (Server Message Block/Common Internet File System) (used with MS Windows systems), AFP (used with Apple Macintosh computers), or NCP (used with OES and Novell NetWare). == Design considerations == === Avoiding single point of failure === The failure of disk hardware or a given storage node in a cluster can create a single point of failure that can result in data loss or unavailability. Fault tolerance and high availability can be provided through data replication of one sort or another, so that data remains intact and available despite the failure of any single piece of equipment. For examples, see the lists of distributed fault-tolerant file systems and distributed parallel fault-tolerant file systems. === Performance === A common performance measurement of a clustered file system is the amount of time needed to satisfy service requests. In conventional systems, this time consists of a disk-access time and a small amount of CPU-processing time. But in a clustered file system, a remote access has additional overhead due to the distributed structure. This includes the time to deliver the request to a server, the time to deliver the response to the client, and for each direction, a CPU overhead of running the communication protocol software. === Concurrency === Concurrency control becomes an issue when more than one person or client is accessing the same file or block and want to update it. Hence updates to the file from one client should not interfere with access and updates from other clients. This problem is more complex with file systems due to concurrent overlapping writes, where different writers write to overlapping regions of the file concurrently. This problem is usually handled by concurrency control or locking which may either be built into the file system or provided by an add-on protocol. == History == IBM mainframes in the 1970s could share physical disks and file systems if each machine had its own channel connection to the drives' control units. In the 1980s, Digital Equipment Corporation's TOPS-20 and OpenVMS clusters (VAX/ALPHA/IA64) included shared disk file systems.

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