Artificial reproduction

Artificial reproduction

Artificial reproduction is the re-creation of life brought about by means other than natural ones. It is new life built by human plans and projects. Examples include artificial selection, artificial insemination, in vitro fertilization, artificial womb, artificial cloning, and kinematic replication. Artificial reproduction is one aspect of artificial life. Artificial reproduction can be categorized into one of two classes according to its capacity to be self-sufficient: non-assisted reproductive technology and assisted reproductive technology. Cutting plants' stems and placing them in compost is a form of assisted artificial reproduction, xenobots are an example of a more autonomous type of reproduction, while the artificial womb presented in the movie the Matrix illustrates a non assisted hypothetical technology. The idea of artificial reproduction has led to various technologies. == Theology == Humans have aspired to create life since immemorial times. Most theologies and religions have conceived this possibility as exclusive of deities. Christian religions consider the possibility of artificial reproduction, in most cases, as heretical and sinful. == Philosophy == Although ancient Greek philosophy raised the concept that man could imitate the creative capacity of nature, classic Greeks thought that if possible, human beings would reproduce things as nature does, and vice versa, nature would do the things that man does in the same way. Aristotle, for example, wrote that if nature made tables, it would make them just as men do. In other words, Aristotle said that if nature were to create a table, such table will look like a human-made table. Correspondingly, Descartes envisioned the human body, and nature, as a machine. Cartesian philosophy does not stop seeing a perfect mirror between nature and the artificial. However, Kant revolutionized this old idea by criticizing such naturalism. Kant pedagogically wrote: "Reason, in order to be taught by nature, must approach nature with its principles in one hand, according to which the agreement among appearances can count as laws, and, in the other hand, the experiment thought out in accord with these principles—in order to be instructed by nature not like a pupil, who has recited to him whatever the teacher wants to say, but like an appointed judge who compels witnesses to answer the questions he puts to them.". Humans are not instructed by nature but rather use nature as raw material to invent. Humans find alternatives to the natural restrictions imposed by natural laws thus, nature is not necessarily mirrored. In accordance with Kant (and contrary to what Aristotle thought) Karl Marx, Alfred Whitehead, Jaques Derrida and Juan David García Bacca noticed that nature is incapable of reproducing tables; or airplanes, or submarines, or computers. If nature tried to create airplanes, it would produce birds. If nature tried to create submarines, it would get fishes. If nature tried to create computers, brains would grow. And if nature tried to create man, modern man, monkeys will be evolved. According to Whitehead, if we look for something natural in artificial life, in the most elaborate cases, if anything, only atoms remain natural. Juan David Garcia Bacca summarized, “It will not come out from wood, it will not be born, a galley; from clay, a vessel; from linen, a dress; from iron, a lever,...From natural, artificial. In the artificial, the natural is reduced to a simple raw material, even though it is perfectly specified with natural specification. The artificial is the real, positive, and original negation of the natural: of species, of genus and of essence. Thus, its ontology is superior to natural ontology. And for this very reason Marx did not attach any importance to Darwin, whose evolutionism is confined to the natural order: to changes, at most, from variety to variety, from species to species... natural. For the same reason, nature has no dialectics, even though continuous evolution and selection can occur. The dialectic cannot emerge from the natural, for deeper reasons than, using today's terms, from a bird, an airplane cannot emerge; from fish, a submarine; from ears, a telephone; from eyes, a television; from a brain, a digital computer; from feet, a car; from hands, an engine; from Euclid, Descartes; from Aristotle, Newton; from Plato, Marx.” According to García Bacca, the major difference between natural causes and artificial causes is that nature does not have plans and projects, while humans design things following plans and projects. In contrast, other influential authors such as Michael Behe have depicted the concept and promoted the idea of intelligent design, a notion that has aroused several doubts and heated controversies, as it reframe natural causes in accordance with a natural plan. Previous ideas that have also provided a positive 'sense' to natural reproduction, are orthogenesis, syntropy, orgone and morphic resonance, among others. Although, these ideas have been historically marginalized and often called pseudoscience, recently Bio-semioticians are reconsidering some of them under symbolic approaches. Current metaphysics of science actually recognizes that the artificial ways of reproduction are diverse from nature, i.e., unnatural, anti-natural or supernatural. Because Biosemiotics does not focus on the function of life but on its meaning, it has a better understanding of the artificial than classic biology. == Science == Biology, being the study of cellular life, addresses reproduction in terms of growth and cellular division (i.e., binary fission, mitosis and meiosis); however, the science of artificial reproduction is not restricted by the mirroring of these natural processes.The science of artificial reproduction is actually transcending the natural forms, and natural rules, of reproduction. For example, xenobots have redefined the classical conception of reproduction. Although xenobots are made of eukariotic cells they do not reproduce by mitosis, but rather by kinematic replication. Such constructive replication does not involve growing but rather building. == Assisted reproductive technologies == Assisted reproductive technology (ART)'s purpose is to assist the development of a human embryo, commonly because of medical concerns due to fertility limitations. == Non-assisted reproductive technologies == Non-assisted reproductive technologies (NART) could have medical motivations but are mostly driven by a wider heterotopic ambition. Although, NARTs are initially designed by humans, they are programed to become independent of humans to a relative or absolute extent. James Lovelock proposed that such novelties could overcome humans. === Artificial cloning === Cloning is the cellular reproductive processes where two or more genetically identical organisms are created, either by natural or artificial means. Artificial cloning normally involves editing the genetic code, somatic cell nuclear transfer and 3D bioprinting. === Non-assisted artificial womb === A non-assisted artificial womb or artificial uterus is a device that allow for ectogenesis or extracorporeal pregnancy by growing an embryonic form outside the body of an organism (that would normally carry the embryo to term) without any human assistance. The aspect of non-assistance is the key distinction between the current artificial womb technology (AWT) in modern medical research, which still relies on human assistance. With this non-assisted hypothetical technology, a zygote or stem cells are used to create an embryo that is then incubated and monitored by artificial intelligence (AI) within a chamber composed of biocompatible material. The AI maintains the necessary conditions for the embryo to develop and thrive, proceeding to mimic organic labor and childbirth in order to best help the embryo adjust to the outside world. Ectogenesis—gestation, depicted in the science fiction movie The Matrix, is a fast approaching reality. This type of innovation presupposes that vertebrate wombs are not the only way for bearing humans or other similar forms of life. === Kinematic replication === Self-replication without binary fission, meiosis, mitosis (or any other form of cellular reproduction that involves division and growing) can be achieved. Xenobots are an example of kinematic replication. They are biobots, named after the African clawed frog (Xenopus laevis). Xenobots are cellular life forms designed by using artificial intelligence to build more of themselves by combining frog cells in a liquid medium. The term kinematic replication is usually reserved for biomolecules (e.g. DNA, RNA, prions, etc.) and artificially designed cellular forms (e.g. xenobots). === Machine constructive replication === Machine constructive replication mimics human traditional manufacturing but is entirely self-automated. Such constructive replication is a more general form of kinematic replication, which does not necessarily

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Audio inpainting

Audio inpainting (also known as audio interpolation) is an audio restoration task which deals with the reconstruction of missing or corrupted portions of a digital audio signal. Inpainting techniques are employed when parts of the audio have been lost due to various factors such as transmission errors, data corruption or errors during recording. The goal of audio inpainting is to fill in the gaps (i.e., the missing portions) in the audio signal seamlessly, making the reconstructed portions indistinguishable from the original content and avoiding the introduction of audible distortions or alterations. Many techniques have been proposed to solve the audio inpainting problem and this is usually achieved by analyzing the temporal and spectral information surrounding each missing portion of the considered audio signal. Classic methods employ statistical models or digital signal processing algorithms to predict and synthesize the missing or damaged sections. Recent solutions, instead, take advantage of deep learning models, thanks to the growing trend of exploiting data-driven methods in the context of audio restoration. Depending on the extent of the lost information, the inpainting task can be divided in three categories. Short inpainting refers to the reconstruction of few milliseconds (approximately less than 10) of missing signal, that occurs in the case of short distortions such as clicks or clipping. In this case, the goal of the reconstruction is to recover the lost information exactly. In long inpainting instead, with gaps in the order of hundreds of milliseconds or even seconds, this goal becomes unrealistic, since restoration techniques cannot rely on local information. Therefore, besides providing a coherent reconstruction, the algorithms need to generate new information that has to be semantically compatible with the surrounding context (i.e., the audio signal surrounding the gaps). The case of medium duration gaps lays between short and long inpainting. It refers to the reconstruction of tens of millisecond of missing data, a scale where the non-stationary characteristic of audio already becomes important. == Definition == Consider a digital audio signal x {\displaystyle \mathbf {x} } . A corrupted version of x {\displaystyle \mathbf {x} } , which is the audio signal presenting missing gaps to be reconstructed, can be defined as x ~ = m ∘ x {\displaystyle \mathbf {\tilde {x}} =\mathbf {m} \circ \mathbf {x} } , where m {\displaystyle \mathbf {m} } is a binary mask encoding the reliable or missing samples of x {\displaystyle \mathbf {x} } , and ∘ {\displaystyle \circ } represents the element-wise product. Audio inpainting aims at finding x ^ {\displaystyle \mathbf {\hat {x}} } (i.e., the reconstruction), which is an estimation of x {\displaystyle \mathbf {x} } . This is an ill-posed inverse problem, which is characterized by a non-unique set of solutions. For this reason, similarly to the formulation used for the inpainting problem in other domains, the reconstructed audio signal can be found through an optimization problem that is formally expressed as x ^ ∗ = argmin X ^ L ( m ∘ x ^ , x ~ ) + R ( x ^ ) {\displaystyle \mathbf {\hat {x}} ^{}={\underset {\hat {\mathbf {X} }}{\text{argmin}}}~L(\mathbf {m} \circ \mathbf {\hat {x}} ,\mathbf {\tilde {x}} )+R(\mathbf {\hat {x}} )} . In particular, x ^ ∗ {\displaystyle \mathbf {\hat {x}} ^{}} is the optimal reconstructed audio signal and L {\displaystyle L} is a distance measure term that computes the reconstruction accuracy between the corrupted audio signal and the estimated one. For example, this term can be expressed with a mean squared error or similar metrics. Since L {\displaystyle L} is computed only on the reliable frames, there are many solutions that can minimize L ( m ∘ x ^ , x ~ ) {\displaystyle L(\mathbf {m} \circ \mathbf {\hat {x}} ,\mathbf {\tilde {x}} )} . It is thus necessary to add a constraint to the minimization, in order to restrict the results only to the valid solutions. This is expressed through the regularization term R {\displaystyle R} that is computed on the reconstructed audio signal x ^ {\displaystyle \mathbf {\hat {x}} } . This term encodes some kind of a-priori information on the audio data. For example, R {\displaystyle R} can express assumptions on the stationarity of the signal, on the sparsity of its representation or can be learned from data. == Techniques == There exist various techniques to perform audio inpainting. These can vary significantly, influenced by factors such as the specific application requirements, the length of the gaps and the available data. In the literature, these techniques are broadly divided in model-based techniques (sometimes also referred as signal processing techniques) and data-driven techniques. === Model-based techniques === Model-based techniques involve the exploitation of mathematical models or assumptions about the underlying structure of the audio signal. These models can be based on prior knowledge of the audio content or statistical properties observed in the data. By leveraging these models, missing or corrupted portions of the audio signal can be inferred or estimated. An example of a model-based techniques are autoregressive models. These methods interpolate or extrapolate the missing samples based on the neighboring values, by using mathematical functions to approximate the missing data. In particular, in autoregressive models the missing samples are completed through linear prediction. The autoregressive coefficients necessary for this prediction are learned from the surrounding audio data, specifically from the data adjacent to each gap. Some more recent techniques approach audio inpainting by representing audio signals as sparse linear combinations of a limited number of basis functions (as for example in the Short Time Fourier Transform). In this context, the aim is to find the sparse representation of the missing section of the signal that most accurately matches the surrounding, unaffected signal. The aforementioned methods exhibit optimal performance when applied to filling in relatively short gaps, lasting only a few tens of milliseconds, and thus they can be included in the context of short inpainting. However, these signal-processing techniques tend to struggle when dealing with longer gaps. The reason behind this limitation lies in the violation of the stationarity condition, as the signal often undergoes significant changes after the gap, making it substantially different from the signal preceding the gap. As a way to overcome these limitations, some approaches add strong assumptions also about the fundamental structure of the gap itself, exploiting sinusoidal modeling or similarity graphs to perform inpainting of longer missing portions of audio signals. === Data-driven techniques === Data-driven techniques rely on the analysis and exploitation of the available audio data. These techniques often employ deep learning algorithms that learn patterns and relationships directly from the provided data. They involve training models on large datasets of audio examples, allowing them to capture the statistical regularities present in the audio signals. Once trained, these models can be used to generate missing portions of the audio signal based on the learned representations, without being restricted by stationarity assumptions. Data-driven techniques also offer the advantage of adaptability and flexibility, as they can learn from diverse audio datasets and potentially handle complex inpainting scenarios. As of today, such techniques constitute the state-of-the-art of audio inpainting, being able to reconstruct gaps of hundreds of milliseconds or even seconds. These performances are made possible by the use of generative models that have the capability to generate novel content to fill in the missing portions. For example, generative adversarial networks, which are the state-of-the-art of generative models in many areas, rely on two competing neural networks trained simultaneously in a two-player minmax game: the generator produces new data from samples of a random variable, the discriminator attempts to distinguish between generated and real data. During the training, the generator's objective is to fool the discriminator, while the discriminator attempts to learn to better classify real and fake data. In GAN-based inpainting methods the generator acts as a context encoder and produces a plausible completion for the gap only given the available information surrounding it. The discriminator is used to train the generator and tests the consistency of the produced inpainted audio. Recently, also diffusion models have established themselves as the state-of-the-art of generative models in many fields, often beating even GAN-based solutions. For this reason they have also been used to solve the audio inpainting problem, obtaining valid results. These models generate new data instances by inverting the

Smart speaker industry in South Korea

Smart speakers, or AI speakers, have been developed by multiple domestic electronics and telecommunications firms in South Korea. Since their introduction to the local market in 2016, they have been used by millions of people in the country. == Brands == === Google === In September 2018, Google Home (including the Google Home Mini) launched in South Korea. Running Google Assistant, it featured simultaneous recognition of two languages among a total of seven, including Korean. At launch, it could play music from Bugs!, in addition to YouTube. === Kakao === In November 2017, Kakao launched the Kakao Mini, featuring integrated KakaoTalk functionality. === KT === KT launched the GiGA Genie smart speaker in January 2017, using a Harman Kardon speaker. In November 2017, KT announced GiGA Genie LTE, a portable AI speaker with LTE support. They also released a mini speaker called GiGA Genie Buddy. In 2018, KT created a special version of GiGa Genie with a screen for use in hotels. On 29 April 2019, KT announced the GiGA Genie Table TV, a consumer-oriented smart speaker with a display. It featured paid TV access through Wi-Fi. Based on usage data from the hotel model, KT decided not to add a touchscreen. The Table TV also featured a limited-access "personalized-text-to-speech technology" which could use parents' voice recording inputs to read children books. In February 2022, KT began rolling out Amazon Alexa integration into its speakers for English support. === Naver === In August 2017, Naver announced the Wave smart speaker, operating on Clova. In October 2017, Naver launched the Friends smart speaker, which were designed based on Line characters. ==== LG Uplus ==== In December 2017, LG Uplus launched the Friends+ speaker with Naver, operating on U+ Home AI. === Samsung === In August 2018, Samsung announced the Samsung Galaxy Home in partnership with Spotify. The original size was delayed, while the Galaxy Home Mini appeared briefly as a bonus for Samsung Galaxy S20 preorders in South Korea in February 2020. === SK Telecom === SK Telecom launched the Nugu smart speaker in September 2016, using an Astell & Kern audio system. In August 2017, SKT released a portable speaker named Nugu mini. In July 2018, SKT launched the Nugu Candle, featuring expanded mood lighting. The first-generation Nugu was subsequently discontinued. On 18 April 2019, SKT released the NUGU Nemo AI, which featured a display and JBL stereo speaker. In August 2019, SKT collaborated with SM Entertainment, incorporating functions related to the agency's artists into Nugu. In January 2022, SKT showcased the NUGU Candle SE, introducing Alexa support. == Usage == In 2018, approximately 3 million people in South Korea used smart speakers. According to data from KT in 2018, the most common commands to its speakers were for controlling televisions. Based on a broader survey in 2017, music was selected as the most frequent use case. By 2018, smart speaker companies were partnering with reading and other education services, adding potential use-cases for children. By 2022, smart speakers were being utilized by the South Korean government. SKT, in partnership with 70 regional governments, distributed smart speakers to 12,000 senior citizens living alone. The government paid for monthly subscriptions to help seniors stay mentally engaged. Naver made an agreement with the Seoul Metropolitan Government to provide Clova CareCall, an automated health checkup program to hundreds of senior citizens living alone. KT's AI care service included an emergency dispatch call function and medication notifications. == Criticism == === Communication === In a survey of 300 users in 2017, approximately half reported having some type of communication issue with their smart speakers. === Privacy === South Korean smart speakers sparked privacy concerns when they were found to be collecting and documenting user audio data in 2019. The speaker companies responded that only a minority of data was collected and that it was anonymized. They stated that such recordings were collected for performance improvements.

Deep tomographic reconstruction

Deep Tomographic Reconstruction is a set of methods for using deep learning methods to perform tomographic reconstruction of medical and industrial images. It uses artificial intelligence and machine learning, especially deep artificial neural networks or deep learning, to overcome challenges such as measurement noise, data sparsity, image artifacts, and computational inefficiency. This approach has been applied across various imaging modalities, including CT, MRI, PET, SPECT, ultrasound, and optical imaging == Historical background == Traditional tomographic reconstruction relies on analytic methods such as filtered back-projection, or iterative methods which incrementally compute inverse transformations from measurement data (e.g., Radon or Fourier transform data). However, these approaches are not sufficient for certain imaging techniques such as low-dose CT and fast MRI, or scenarios involving metal artifacts and patient motion. == Use in imaging modalities == === Computed tomography (CT) === In CT, deep learning models can be particularly effective in reducing radiation exposure while maintaining image quality. Deep neural networks can also be able to reconstruct images of fair quality from sparsely sampled data without sacrificing diagnostic performance. Deep learning-based generative AI models can reduce CT metal artifacts. === Magnetic resonance imaging (MRI) === In magnetic resonance imaging (MRI), deep learning can lead to reduced MRI motion artifacts, and increased acquisition speed, referred to as fast MRI. Despite suffering from disadvantages such as lower signal-to-noise ratio (SNR), deep learning can enhance image quality in low field MRI, making these systems clinically viable. === Positron emission tomography (PET) and single-photon emission CT (SPECT) === For PET imaging, deep learning models can provide substantial improvements in low-dose imaging and motion artifact correction. Also, deep learning can help SPECT for generation of attenuation background. A notable technique for PET denoising involves integrating MR data through multimodal networks, which use anatomical information from MRI to enhance PET image quality. === Ultrasound imaging === Deep learning can enhance ultrasound imaging by reducing speckle noise and motion blur. For ultrasound beamforming, deep neural networks can allow superior image quality with limited data at high speed. === Optical imaging and microscopy === Diffuse optical tomography, optical coherence tomography and microscopy can be improved by deep neural networks beyond traditional methods. Furthermore, deep learning can also enhance Photoacoustic imaging (see Deep learning in photoacoustic imaging), addressing challenges like high noise, low contrast, and limited resolution. Deep learning has also been applied to label-free live-cell imaging, where convolutional neural networks predict fluorescence labels from transmitted light images, a technique known as in silico labeling. This method can enable high-throughput, non-invasive cell analysis and phenotyping without the need for traditional fluorescent dyes.

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Business process automation

Business process automation (BPA), also known as business automation, refers to the technology-enabled automation of business processes. == Development approaches == There are three main approaches to developing BPA: traditional business process automation involves developing BPA software in a programming language for integrating relevant applications in the digital ecosystem to execute a given process; robotic process automation uses software robots (also called agents, bots, or workers) to emulate human-computer interaction for executing a combination of processes, activities, transactions, and tasks in one or more unrelated software systems; hyperautomation (also called intelligent automation (IA), intelligent process automation (IPA), integrated automation platform (IAP), and cognitive automation (CA) combines business process automation, artificial intelligence (AI), and machine learning (ML) to discover, validate, and execute organizational processes automatically with no or minimal human intervention. == Deployment == BPA toolsets vary in capability. With the increasing adoption of artificial intelligence (AI), organizations are implementing AI-driven technologies that can process natural language, interpret unstructured datasets, and interact with users. These systems are designed to adapt to new types of problems with reduced reliance on human intervention. == Business process management implementation == A business process management system differs from BPA. However, it is possible to implement automation based on a BPM implementation. The methods to achieve this vary, from writing custom application code to using specialist BPA tools. == Robotic process automation == Robotic process automation (RPA) involves the deployment of attended or unattended software agents in an organization's environment. These software agents, or robots, are programmed to perform predefined structured and repetitive sets of business tasks or processes. Robotic process automation is designed to streamline workflows by delegating repetitive tasks to software agents, allowing human workers to focus on more complex and strategic activities. BPA providers typically focus on different industry sectors, but the underlying approach is generally similar in that they aim to provide the shortest route to automation by interacting with the user interface rather than modifying the application code or database behind it. == Use of artificial intelligence == Artificial intelligence software robots are used to handle unstructured data sets (like images, texts, audios) and are often deployed after implementing robotic process automation. They can, for instance, generate an automatic transcript from a video. The combination of automation and artificial intelligence (AI) enables autonomy for robots, along with the capability to perform cognitive tasks. At this stage, robots can learn and improve processes by analyzing and adapting them.