In formal language theory, the Kleene star (or Kleene operator or Kleene closure) refers to two related unary operations, that can be applied either to an alphabet of symbols or to a formal language, a set of strings (finite sequences of symbols). The Kleene star operator on an alphabet V generates the set V of all finite-length strings over V, that is, finite sequences whose elements belong to V; in mathematics, it is more commonly known as the free monoid construction. The Kleene star operator on a language L generates another language L, the set of all strings that can be obtained as a concatenation of zero or more members of L. In both cases, repetitions are allowed. The Kleene star operators are named after American mathematician Stephen Cole Kleene, who first introduced and widely used it to characterize automata for regular expressions. == Of an alphabet == Given an alphabet V {\displaystyle V} , define V 0 = { ε } {\displaystyle V^{0}=\{\varepsilon \}} (the set consists only of the empty string), V 1 = V , {\displaystyle V^{1}=V,} and define recursively the set V i + 1 = { w v : w ∈ V i and v ∈ V } {\displaystyle V^{i+1}=\{wv:w\in V^{i}{\text{ and }}v\in V\}} for each i > 0 , {\displaystyle i>0,} where w v {\displaystyle wv} denotes the string obtained by appending the single character v {\displaystyle v} to the end of w {\displaystyle w} . Here, V i {\displaystyle V^{i}} can be understood to be the set of all strings of length exactly i {\displaystyle i} , with characters from V {\displaystyle V} . The definition of Kleene star on V {\displaystyle V} is V ∗ = ⋃ i ≥ 0 V i = V 0 ∪ V 1 ∪ V 2 ∪ V 3 ∪ V 4 ∪ ⋯ . {\displaystyle V^{}=\bigcup _{i\geq 0}V^{i}=V^{0}\cup V^{1}\cup V^{2}\cup V^{3}\cup V^{4}\cup \cdots .} == Of a language == Given a language L {\displaystyle L} (any finite or infinite set of strings), define L 0 = { ε } {\displaystyle L^{0}=\{\varepsilon \}} (the language consisting only of the empty string), L 1 = L , {\displaystyle L^{1}=L,} and define recursively the set L i + 1 = { w v : w ∈ L i and v ∈ L } {\displaystyle L^{i+1}=\{wv:w\in L^{i}{\text{ and }}v\in L\}} for each i > 0 , {\displaystyle i>0,} where w v {\displaystyle wv} denotes the string obtained by concatenating w {\displaystyle w} and v {\displaystyle v} . Here, L i {\displaystyle L^{i}} can be understood to be the set of all strings that can be obtained by concatenating exactly i {\displaystyle i} strings from L {\displaystyle L} , allowing repetitions. The definition of Kleene star on L {\displaystyle L} is L ∗ = ⋃ i ≥ 0 L i = L 0 ∪ L 1 ∪ L 2 ∪ L 3 ∪ L 4 ∪ ⋯ . {\displaystyle L^{}=\bigcup _{i\geq 0}L^{i}=L^{0}\cup L^{1}\cup L^{2}\cup L^{3}\cup L^{4}\cup \cdots .} == Kleene plus == In some formal language studies, (e.g. AFL theory) a variation on the Kleene star operation called the Kleene plus is used. The Kleene plus omits the V 0 {\displaystyle V^{0}} or L 0 {\displaystyle L^{0}} term in the above unions. In other words, the Kleene plus on V {\displaystyle V} is V + = ⋃ i ≥ 1 V i = V 1 ∪ V 2 ∪ V 3 ∪ ⋯ , {\displaystyle V^{+}=\bigcup _{i\geq 1}V^{i}=V^{1}\cup V^{2}\cup V^{3}\cup \cdots ,} or V + = V ∗ V . {\displaystyle V^{+}=V^{}V.} == Examples == Example of Kleene star applied to a set of strings: {"ab","c"} = { ε, "ab", "c", "abab", "abc", "cab", "cc", "ababab", "ababc", "abcab", "abcc", "cabab", "cabc", "ccab", "ccc", ...}. Example of Kleene star applied to a set of strings without the prefix property: {"a","ab","b"} = { ε, "a", "ab", "b", "aa", "aab", "aba", "abab", "abb", "ba", "bab", "bb", ...};In this example, the string "aab" can be obtained in two different ways. The Sardinas-Patterson algorithm can be used to check for a given V whether any member of V can be obtained in more than one way. Example of Kleene and Kleene plus applied to a set of characters (following the C programming language convention where a character is denoted by single quotes and a string is denoted by double quotes): {'a', 'b', 'c'} = { ε, "a", "b", "c", "aa", "ab", "ac", "ba", "bb", "bc", "ca", "cb", "cc", "aaa", "aab", ...}. {'a', 'b', 'c'}+ = { "a", "b", "c", "aa", "ab", "ac", "ba", "bb", "bc", "ca", "cb", "cc", "aaa", "aab", ...}. == Properties == If V {\displaystyle V} is any finite or countably infinite set of characters, then V ∗ {\displaystyle V^{}} is a countably infinite set. As a result, each formal language over a finite or countably infinite alphabet Σ {\displaystyle \Sigma } is countable, since it is a subset of the countably infinite set Σ ∗ {\displaystyle \Sigma ^{}} . ( L ∗ ) ∗ = L ∗ {\displaystyle (L^{})^{}=L^{}} , which means that the Kleene star operator is an idempotent unary operator, as ( L ∗ ) i = L ∗ {\displaystyle (L^{})^{i}=L^{}} for every i ≥ 1 {\displaystyle i\geq 1} . V ∗ = { ε } {\displaystyle V^{}=\{\varepsilon \}} , if V {\displaystyle V} is the empty set ∅. For the version of the Kleene star operator on languages, L ∗ = { ε } {\displaystyle L^{}=\{\varepsilon \}} when L {\displaystyle L} is either the empty set ∅ or the singleton set { ε } {\displaystyle \{\varepsilon \}} . == Generalization == Strings form a monoid with concatenation as the binary operation and ε the identity element. In addition to strings, the Kleene star is defined for any monoid. More precisely, let (M, ⋅) be a monoid, and S ⊆ M. Then S is the smallest submonoid of M containing S; that is, S contains the neutral element of M, the set S, and is such that if x,y ∈ S, then x⋅y ∈ S. Furthermore, the Kleene star is generalized by including the -operation (and the union) in the algebraic structure itself by the notion of complete star semiring.
Radar geo-warping
Radar geo-warping is the adjustment of geo-referenced radar images and video data to be consistent with a geographical projection. This image warping avoids any restrictions when displaying it together with video from multiple radar sources or with other geographical data including scanned maps and satellite images which may be provided in a particular projection. There are many areas where geo warping has unique benefits: Single radar video signal displayed together with maps of different geographical projections. E.g. Mercator UTM stereographic Multiple radar video signals displayed simultaneously: Having the computing power to do so on one computer. Adapting the projection of all radar signals allowing the geographically correct display and accurate superimposition of those videos. Slant range correction: a modern 3D radar system can measure the height of a target and hence it is possible to correct the radar video by the real corrected range of the target. Slant Range Correction also allows to compensate the radar tower height e.g. for maritime surveillance radars. == Introduction == Radar video presents the echoes of electromagnetic waves a radar system has emitted and received as reflections afterwards. These echoes are typically presented on a computer screen with a color-coding scheme depicting the reflection strength. Two problems have to be solved during such a visualization process. The first problem arises from the fact that typically the radar antenna turns around its position and measures the reflection echo distances from its position in one direction. This effectively means that the radar video data are present in polar coordinates. In older systems the polar oriented picture has been displayed in so called plan position indicators (PPI). The PPI-scope uses a radial sweep pivoting about the center of the presentation. This results in a map-like picture of the area covered by the radar beam. A long-persistence screen is used so that the display remains visible until the sweep passes again. Bearing to the target is indicated by the target's angular position in relation to an imaginary line extending vertically from the sweep origin to the top of the scope. The top of the scope is either true north (when the indicator is operated in the true bearing mode) or ship's heading (when the indicator is operated in the relative bearing mode). For visualization on a modern computer screen the polar coordinates have to be converted into Cartesian coordinates. This process called radar scan conversion is presented with more detail in the next section. The second problem to solve arises from the fact that a radar system is placed in the real world and measures real world echo positions. These echoes have to be displayed together with other real world data like object positions, vector maps and satellite images in a consistent way. All this information refers to the curved earth surface but is displayed on a flat computer display. Building a link from real world earth positions to display pixels is commonly called geographical referencing or in short geo-referencing. Part of the geo-referencing process is to map the 3D earth surface onto a 2D display. This process of a geographical projection can be performed in many ways, but different data sources have their own 'natural' projection. E.g. Cartesian radar video data from a radar source on the earth surface are geo-referenced by a so-called radar projection. When using this radar projection the Cartesian radar video pixels can directly displayed on a computer screen (only being linearly transformed according to the current position on the screen and e.g. the current zoom level). A problem now arises if e.g. also a satellite map shall be shown together with the radar video data. The 'natural' geographical projection of a satellite image would be a satellite projection which depends on the satellite orbit, position and further parameters. Now either the satellite image has to be reprojected to a radar projection or the radar video has to use the satellite projection. This geographical re-projection is also called geographical warping or Geo Warping where each image pixel has to be transformed from one projection into another. This article describes in further detail the Geo Warping of radar video images in real time. It will also show that radar video Geo Warping is done most efficiently when it is integrated with the radar scan conversion process. == Radar-scan conversion == This section describes the principles of the radar-scan conversion (RSC) process. The radar supplies its measured data in polar coordinates (ρ,θ) directly from the rotating antenna. ρ defines the target/echo distance and θ the target angle in polar world coordinates. These data are measured, digitized and stored in a polar coordinate polar store or polar pixmap. The main RSC task is to convert these data to Cartesian (x, y) display coordinates, creating the necessary display pixels. The RSC process is influenced by the current zoom, shift and rotation settings defining which part of the 'world' shall be visible in the display image. As detailed later the RSC process also takes the currently used geographical projection into account when the radar video images are Geo Warped. The OpenGL RSC is implemented using a reverse scan conversion approach which calculates for every image pixel the most appropriate radar amplitude value in the polar store. This approach generates an optimal image without any artifacts known from forward spoke fill algorithms. By applying bi-linear filtering between adjacent pixels in the polar store during the conversion process the OpenGL RSC finally achieves a very high visual quality radar display image for every zoom level, creating smooth images of the radar echoes. == Radar projection == This section illustrates how radar video data are geo referenced and displayed on a computer screen. The radar sensor is positioned on the earth surface with a height h above the ground. It measures the direct distance d to the target (and not e.g. the distance the target is away from the radar if one would move on the earth surface). This distance is then used in the display plane after adjustment to the current display zoom level by the radar scan converter (RSC). Now it has to be clarified how the radar video data is geo referenced. This basically means, that if we want to display a geographical real world object (like e.g. a light house) which is at the same real world position as the radar target, that it also shall appear at the same position in the display plane. This is realized by calculating the distance from the radar sensor to the respective real world object and use that distance in the display plane. The position of the real world object is typically given in geographical coordinates (latitude, longitude and height above the earth surface). In other words, using a radar projection with geographical data is done by simulating a radar measurement process with the real world objects and use the resulting range and azimuth in the display plane. The second picture to the right shows an example radar projection with the center of projection (COP) at latitude 50.0° and longitude 0.0° which is also the radar position. The dashed lines are the equal-latitude and equal-longitude lines on top of the background map. The solid lines show equal-range and equal-azimuth with the respect to the radar position. It is a feature of the radar projection that equal-range lines are circles and equal-azimuth lines are straight lines. This is necessary to display radar video consistently with other map data when using a radar projection where the projection center has to be the radar position. == Geo Warping process == This section explains the actual geo warping or re-projection process when applied to radar video in real time. Assume we want to display radar video on top of a satellite image. As an example we use the CIB projection which is used to display satellite data in CIB (Controlled Image Base) format. The Figure Geo Warping Radar to CIB Projection shows dashed the maximal range circle for a range of 111 km or 60 miles using the radar projection. Such a range is typical for long range coastal surveillance radars. As stated in the last section this is a perfect circle also on the computer screen. The solid line ellipse shows the same range circle for the CIB projection. Typically the errors occurring without Geo Warping are smallest near the radar position if at least the projection center (COP) coincides with the radar position, as realized in our example. Otherwise the error distribution depends both on the used projection and also on the projection parameters. Thus, in our case the errors are most significant near the maximum radar range. The CIB projection error corrected in east–west direction at half the radar range is 2.6 km and is 5.3 km at the full radar range of 111 km. An error of 5.3 km is
Q-learning
Q-learning is a reinforcement learning algorithm that trains an agent to assign values to its possible actions based on its current state, without requiring a model of the environment (model-free). It can handle problems with stochastic transitions and rewards without requiring adaptations. For example, in a grid maze, an agent learns to reach an exit worth 10 points. At a junction, Q-learning might assign a higher value to moving right than left if right gets to the exit faster, improving this choice by trying both directions over time. For any finite Markov decision process, Q-learning finds an optimal policy in the sense of maximizing the expected value of the total reward over any and all successive steps, starting from the current state. Q-learning can identify an optimal action-selection policy for any given finite Markov decision process, given infinite exploration time and a partly random policy. "Q" refers to the function that the algorithm computes: the expected reward—that is, the quality—of an action taken in a given state. == Reinforcement learning == Reinforcement learning involves an agent, a set of states S {\displaystyle {\mathcal {S}}} , and a set A {\displaystyle {\mathcal {A}}} of actions per state. By performing an action a ∈ A {\displaystyle a\in {\mathcal {A}}} , the agent transitions from state to state. Executing an action in a specific state provides the agent with a reward (a numerical score). The goal of the agent is to maximize its total reward. It does this by adding the maximum reward attainable from future states to the reward for achieving its current state, effectively influencing the current action by the potential future reward. This potential reward is a weighted sum of expected values of the rewards of all future steps starting from the current state. As an example, consider the process of boarding a train, in which the reward is measured by the negative of the total time spent boarding (alternatively, the cost of boarding the train is equal to the boarding time). One strategy is to enter the train door as soon as they open, minimizing the initial wait time for yourself. If the train is crowded, however, then you will have a slow entry after the initial action of entering the door as people are fighting you to depart the train as you attempt to board. The total boarding time, or cost, is then: 0 seconds wait time + 15 seconds fight time On the next day, by random chance (exploration), you decide to wait and let other people depart first. This initially results in a longer wait time. However, less time is spent fighting the departing passengers. Overall, this path has a higher reward than that of the previous day, since the total boarding time is now: 5 second wait time + 0 second fight time Through exploration, despite the initial (patient) action resulting in a larger cost (or negative reward) than in the forceful strategy, the overall cost is lower, thus revealing a more rewarding strategy. == Algorithm == After Δ t {\displaystyle \Delta t} steps into the future the agent will decide some next step. The weight for this step is calculated as γ Δ t {\displaystyle \gamma ^{\Delta t}} , where γ {\displaystyle \gamma } (the discount factor) is a number between 0 and 1 ( 0 ≤ γ ≤ 1 {\displaystyle 0\leq \gamma \leq 1} ). Assuming γ < 1 {\displaystyle \gamma <1} , it has the effect of valuing rewards received earlier higher than those received later (reflecting the value of a "good start"). γ {\displaystyle \gamma } may also be interpreted as the probability to succeed (or survive) at every step Δ t {\displaystyle \Delta t} . The algorithm, therefore, has a function that calculates the quality of a state–action combination: Q : S × A → R {\displaystyle Q:{\mathcal {S}}\times {\mathcal {A}}\to \mathbb {R} } . Before learning begins, Q {\displaystyle Q} is initialized to a possibly arbitrary fixed value (chosen by the programmer). Then, at each time t {\displaystyle t} the agent selects an action A t {\displaystyle A_{t}} , observes a reward R t + 1 {\displaystyle R_{t+1}} , enters a new state S t + 1 {\displaystyle S_{t+1}} (that may depend on both the previous state S t {\displaystyle S_{t}} and the selected action), and Q {\displaystyle Q} is updated. The core of the algorithm is a Bellman equation as a simple value iteration update, using the weighted average of the current value and the new information: Q n e w ( S t , A t ) ← ( 1 − α ⏟ learning rate ) ⋅ Q ( S t , A t ) ⏟ current value + α ⏟ learning rate ⋅ ( R t + 1 ⏟ reward + γ ⏟ discount factor ⋅ max a Q ( S t + 1 , a ) ⏟ estimate of optimal future value ⏟ new value (temporal difference target) ) {\displaystyle Q^{new}(S_{t},A_{t})\leftarrow (1-\underbrace {\alpha } _{\text{learning rate}})\cdot \underbrace {Q(S_{t},A_{t})} _{\text{current value}}+\underbrace {\alpha } _{\text{learning rate}}\cdot {\bigg (}\underbrace {\underbrace {R_{t+1}} _{\text{reward}}+\underbrace {\gamma } _{\text{discount factor}}\cdot \underbrace {\max _{a}Q(S_{t+1},a)} _{\text{estimate of optimal future value}}} _{\text{new value (temporal difference target)}}{\bigg )}} where R t + 1 {\displaystyle R_{t+1}} is the reward received when moving from the state S t {\displaystyle S_{t}} to the state S t + 1 {\displaystyle S_{t+1}} , and α {\displaystyle \alpha } is the learning rate ( 0 < α ≤ 1 ) {\displaystyle (0<\alpha \leq 1)} . Note that Q n e w ( S t , A t ) {\displaystyle Q^{new}(S_{t},A_{t})} is the sum of three terms: ( 1 − α ) Q ( S t , A t ) {\displaystyle (1-\alpha )Q(S_{t},A_{t})} : the current value (weighted by one minus the learning rate) α R t + 1 {\displaystyle \alpha \,R_{t+1}} : the reward R t + 1 {\displaystyle R_{t+1}} to obtain if action A t {\displaystyle A_{t}} is taken when in state S t {\displaystyle S_{t}} (weighted by learning rate) α γ max a Q ( S t + 1 , a ) {\displaystyle \alpha \gamma \max _{a}Q(S_{t+1},a)} : the maximum reward that can be obtained from state S t + 1 {\displaystyle S_{t+1}} (weighted by learning rate and discount factor) An episode of the algorithm ends when state S t + 1 {\displaystyle S_{t+1}} is a final or terminal state. However, Q-learning can also learn in non-episodic tasks (as a result of the property of convergent infinite series). If the discount factor is lower than 1, the action values are finite even if the problem can contain infinite loops or paths. For all final states s f {\displaystyle s_{f}} , Q ( s f , a ) {\displaystyle Q(s_{f},a)} is never updated, but is set to the reward value r {\displaystyle r} observed for state s f {\displaystyle s_{f}} . In most cases, Q ( s f , a ) {\displaystyle Q(s_{f},a)} can be taken to equal zero. == Influence of variables == === Learning rate === The learning rate or step size determines to what extent newly acquired information overrides old information. A factor of 0 makes the agent learn nothing (exclusively exploiting prior knowledge), while a factor of 1 makes the agent consider only the most recent information (ignoring prior knowledge to explore possibilities). In fully deterministic environments, a learning rate of α t = 1 {\displaystyle \alpha _{t}=1} is optimal. When the problem is stochastic, the algorithm converges under some technical conditions on the learning rate that require it to decrease to zero. In practice, often a constant learning rate is used, such as α t = 0.1 {\displaystyle \alpha _{t}=0.1} for all t {\displaystyle t} . === Discount factor === The discount factor γ {\displaystyle \gamma } determines the importance of future rewards. A factor of 0 will make the agent "myopic" (or short-sighted) by only considering current rewards, i.e. r t {\displaystyle r_{t}} (in the update rule above), while a factor approaching 1 will make it strive for a long-term high reward. If the discount factor meets or exceeds 1, the action values may diverge. For γ = 1 {\displaystyle \gamma =1} , without a terminal state, or if the agent never reaches one, all environment histories become infinitely long, and utilities with additive, undiscounted rewards generally become infinite. Even with a discount factor only slightly lower than 1, Q-function learning leads to propagation of errors and instabilities when the value function is approximated with an artificial neural network. In that case, starting with a lower discount factor and increasing it towards its final value accelerates learning. === Initial conditions (Q0) === Since Q-learning is an iterative algorithm, it implicitly assumes an initial condition before the first update occurs. High initial values, also known as "optimistic initial conditions", can encourage exploration: no matter what action is selected, the update rule will cause it to have lower values than the other alternative, thus increasing their choice probability. The first reward r {\displaystyle r} can be used to reset the initial conditions. According to this idea, the first time an action is taken the reward is used to set the value
Linguamatics
Linguamatics, headquartered in Cambridge, England, with offices in the United States and UK, is a provider of text mining systems through software licensing and services, primarily for pharmaceutical and healthcare applications. Founded in 2001, the company was purchased by IQVIA in January 2019. == Technology == The company develops enterprise search tools for the life sciences sector. The core natural language processing engine (I2E) uses a federated architecture to incorporate data from 3rd party resources. Initially developed to be used interactively through a graphic user interface, the core software also has an application programming interface that can be used to automate searches. LabKey, Penn Medicine, Atrius Health and Mercy all use Linguamatics software to extract electronic health record data into data warehouses. Linguamatics software is used by 17 of the top 20 global pharmaceutical companies, the US Food and Drug Administration, as well as healthcare providers. == Software community == The core software, "I2E", is used by a number of companies to either extend their own software or to publish their data. Copyright Clearance Center uses I2E to produce searchable indexes of material that would otherwise be unsearchable due to copyright. Thomson Reuters produces Cortellis Informatics Clinical Text Analytics, which depends on I2E to make clinical data accessible and searchable. Pipeline Pilot can integrate I2E as part of a workflow. ChemAxon can be used alongside I2E to allow named entity recognition of chemicals within unstructured data. Data sources include MEDLINE, ClinicalTrials.gov, FDA Drug Labels, PubMed Central, and Patent Abstracts.
Markov blanket
In statistics and machine learning, a Markov blanket of a random variable is a set of variables that renders the variable conditionally independent of all other variables in the system. This concept is central in probabilistic graphical models and feature selection. If a Markov blanket is minimal—meaning that no variable in it can be removed without losing this conditional independence—it is called a Markov boundary. Identifying a Markov blanket or boundary allows for efficient inference and helps isolate relevant variables for prediction or causal reasoning. The terms Markov blanket and Markov boundary were coined by Judea Pearl in 1988. A Markov blanket may be derived from the structure of a probabilistic graphical model such as a Bayesian network or Markov random field. == Definition == A Markov blanket of a random variable Y {\displaystyle Y} in a random variable set S = { X 1 , … , X n } {\displaystyle {\mathcal {S}}=\{X_{1},\ldots ,X_{n}\}} is any subset S 1 {\displaystyle {\mathcal {S}}_{1}} of S {\displaystyle {\mathcal {S}}} , conditioned on which other variables are independent with Y {\displaystyle Y} : Y ⊥ ⊥ S ∖ S 1 ∣ S 1 {\displaystyle Y\perp \!\!\!\perp {\mathcal {S}}\smallsetminus {\mathcal {S}}_{1}\mid {\mathcal {S}}_{1}} It means that S 1 {\displaystyle {\mathcal {S}}_{1}} contains at least all the information one needs to infer Y {\displaystyle Y} , where the variables in S ∖ S 1 {\displaystyle {\mathcal {S}}\smallsetminus {\mathcal {S}}_{1}} are redundant. In general, a given Markov blanket is not unique. Any set in S {\displaystyle {\mathcal {S}}} that contains a Markov blanket is also a Markov blanket itself. Specifically, S {\displaystyle {\mathcal {S}}} is a Markov blanket of Y {\displaystyle Y} in S {\displaystyle {\mathcal {S}}} . === Example === In a Bayesian network, the Markov blanket of a node consists of its parents, its children, and its children's other parents (i.e., co-parents). Knowing the values of these nodes makes the target node conditionally independent of the rest of the network. In a Markov random field, the Markov blanket of a node is simply its immediate neighbors. == Markov condition == The concept of a Markov blanket is rooted in the Markov condition, which states that in a probabilistic graphical model, each variable is conditionally independent of its non-descendants given its parents. This condition implies the existence of a minimal separating set — the Markov blanket — that shields a variable from the rest of the network. For instance, when a person holds an object stationary against gravity, the object’s acceleration is fully determined by its direct causes—namely, the upward force from the hand and the downward gravitational pull. Other variables such as air pressure or temperature are causally irrelevant. == Markov boundary == A Markov boundary of Y {\displaystyle Y} in S {\displaystyle {\mathcal {S}}} is a subset S 2 {\displaystyle {\mathcal {S}}_{2}} of S {\displaystyle {\mathcal {S}}} , such that S 2 {\displaystyle {\mathcal {S}}_{2}} itself is a Markov blanket of Y {\displaystyle Y} , but any proper subset of S 2 {\displaystyle {\mathcal {S}}_{2}} is not a Markov blanket of Y {\displaystyle Y} . In other words, a Markov boundary is a minimal Markov blanket. The Markov boundary of a node A {\displaystyle A} in a Bayesian network is the set of nodes composed of A {\displaystyle A} 's parents, A {\displaystyle A} 's children, and A {\displaystyle A} 's children's other parents. In a Markov random field, the Markov boundary for a node is the set of its neighboring nodes. In a dependency network, the Markov boundary for a node is the set of its parents. === Uniqueness of Markov boundary === The Markov boundary always exists. Under some mild conditions, the Markov boundary is unique. However, for most practical and theoretical scenarios multiple Markov boundaries may provide alternative solutions. When there are multiple Markov boundaries, quantities measuring causal effect could fail. == In cognitive science == In the study of consciousness, brain function, and complex adaptive systems, Markov blankets are proposed as a mathematical mechanism which delimits the extent of cognitive entities, whether it be physical or causal.
Cuboid (computer vision)
In computer vision, the term cuboid is used to describe a small spatiotemporal volume extracted for purposes of behavior recognition. The cuboid is regarded as a basic geometric primitive type and is used to depict three-dimensional objects within a three dimensional representation of a flat, two dimensional image. == Production == Cuboids can be produced from both two-dimensional and three-dimensional images. One method used to produce cuboids utilizes scene understanding (SUN) primitive databases, which are collections of pictures that already contain cuboids. By sorting through SUN primitive databases with machine learning tools, computers observe the conditions in which cuboids are produced in images from SUN primitive databases and can learn to produce cuboids from other images. RGB-D images, which are RGB images that also record the depth of each pixel, are occasionally used to produce cuboids because computers no longer need to determine the depth of an object, as they typically do because depth is already recorded. Cuboid production is sensitive to changes in color and illumination, blockage, and background clutter. This means that it is difficult for computers to produce cuboids of objects that are multicolored, irregularly illuminated, or partially covered, or if there are many objects in the background. This is partially due to the fact that algorithms for producing cuboids are still relatively simple. == Usage == Cuboids are created for point cloud-based three-dimensional maps and can be utilized in various situations such as augmented reality, the automated control of cars, drones, and robots, and object detection. Cuboids allow for software to identify a scene through geometric descriptions in an “object-agnostic” fashion. Interest points, locations within images that are identified by a computer as essential to identifying the image, created from two-dimensional images can be used with cuboids for image matching, identifying a room or scene, and instance recognition. Interest points created from three dimensional images can be used with cuboids to recognize activities. This is possible because interest points aid software to focus on only the most important aspects of the images. RGB-D images and SLAM systems are used together in RGB-D SLAM systems, which are employed by Computer-aided design systems to generate point cloud-based three-dimensional maps. Most industrial multi-axis machining tools use computer-aided manufacturing and subsequently work in cuboid work spaces.
Jpred
Jpred v.4 is the latest version of the JPred Protein Secondary Structure Prediction Server which provides predictions by the JNet algorithm, one of the most accurate methods for secondary structure prediction, that has existed since 1998 in different versions. In addition to protein secondary structure, JPred also makes predictions of solvent accessibility and coiled-coil regions. The JPred service runs up to 134 000 jobs per month and has carried out over 2 million predictions in total for users in 179 countries. == JPred 2 == The static HTML pages of JPred 2 are still available for reference. == JPred 3 == The JPred v3 followed on from previous versions of JPred developed and maintained by James Cuff and Jonathan Barber (see JPred References). This release added new functionality and fixed many bugs. The highlights are: New, friendlier user interface Retrained and optimised version of Jnet (v2) - mean secondary structure prediction accuracy of >81% Batch submission of jobs Better error checking of input sequences/alignments Predictions now (optionally) returned via e-mail Users may provide their own query names for each submission JPred now makes a prediction even when there are no PSI-BLAST hits to the query PS/PDF output now incorporates all the predictions == JPred 4 == The current version of JPred (v4) has the following improvements and updates incorporated: Retrained on the latest UniRef90 and SCOPe/ASTRAL version of Jnet (v2.3.1) - mean secondary structure prediction accuracy of >82%. Upgraded the Web Server to the latest technologies (Bootstrap framework, JavaScript) and updating the web pages – improving the design and usability through implementing responsive technologies. Added RESTful API and mass-submission and results retrieval scripts - resulting in peak throughput above 20,000 predictions per day. Added prediction jobs monitoring tools. Upgraded the results reporting – both, on the web-site, and through the optional email summary reports: improved batch submission, added results summary preview through Jalview results visualization summary in SVG and adding full multiple sequence alignments into the reports. Improved help-pages, incorporating tool-tips, and adding one-page step-by-step tutorials. Sequence residues are categorised or assigned to one of the secondary structure elements, such as alpha-helix, beta-sheet and coiled-coil. Jnet uses two neural networks for its prediction. The first network is fed with a window of 17 residues over each amino acid in the alignment plus a conservation number. It uses a hidden layer of nine nodes and has three output nodes, one for each secondary structure element. The second network is fed with a window of 19 residues (the result of first network) plus the conservation number. It has a hidden layer with nine nodes and has three output nodes.