The Ontology for Biomedical Investigations (OBI) is an open-access, integrated ontology for the description of biological and clinical investigations. OBI provides a model for the design of an investigation, the protocols and instrumentation used, the materials used, the data generated and the type of analysis performed on it. The project is being developed as part of the OBO Foundry and as such adheres to all the principles therein such as orthogonal coverage (i.e. clear delineation from other foundry member ontologies) and the use of a common formal language. In OBI the common formal language used is the Web Ontology Language (OWL). As of March 2008, a pre-release version of the ontology was made available at the project's SVN repository. == Scope == The Ontology for Biomedical Investigations (OBI) addresses the need for controlled vocabularies to support integration and joint ("cross-omics") analysis of experimental data, a need originally identified in the transcriptomics domain by the FGED Society, which developed the MGED Ontology as an annotation resource for microarray data.Smith B, Ashburner M, Rosse C, Bard J, Bug W, Ceusters W, et al. (November 2007). "The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration". Nature Biotechnology. 25 (11): 1251–5. doi:10.1038/nbt1346. PMC 2814061. PMID 17989687. OBI uses the basic formal ontology upper-level ontology as a means of describing general entities that do not belong to a specific problem domain. As such, all OBI classes are a subclass of some BFO class. The ontology has the scope of modeling all biomedical investigations and as such contains ontology terms for aspects such as: biological material – for example blood plasma instrument (and parts of an instrument therein) – for example DNA microarray, centrifuge information content – such as an image or a digital information entity such as an electronic medical record design and execution of an investigation (and individual experiments therein) – for example study design, electrophoresis material separation data transformation (incorporating aspects such as data normalization and data analysis) – for example principal components analysis dimensionality reduction, mean calculation Less 'concrete' aspects such as the role a given entity may play in a particular scenario (for example the role of a chemical compound in an experiment) and the function of an entity (for example the digestive function of the stomach to nutriate the body) are also covered in the ontology. == OBI consortium == The MGED Ontology was originally identified in the transcriptomics domain by the FGED Society and was developed to address the needs of data integration. Following a mutual decision to collaborate, this effort later became a wider collaboration between groups such as FGED, PSI and MSI in response to the needs of areas such as transcriptomics, proteomics and metabolomics and the FuGO (Functional Genomics Investigation Ontology) was created. This later became the OBI covering the wider scope of all biomedical investigations. As an international, cross-domain initiative, the OBI consortium draws upon a pool of experts from a variety of fields, not limited to biology. The current list of OBI consortium members is available at the OBI consortium website. The consortium is made up of a coordinating committee which is a combination of two subgroups, the Community Representative (those representing a particular biomedical community) and the Core Developers (ontology developers who may or may not be members of any single community). Separate to the coordinating committee is the Developers Working Group which consists of developers within the communities collaborating in the development of OBI at the discretion of current OBI Consortium members. == Papers on OBI ==
Cheekd
Cheekd is a dating app based in New York City. It was founded in 2010 by Lori Cheek. == History == The service debuted with the name "Cheek'd". Founder Lori Cheek appeared on the television program, Shark Tank in February 2014, but did not succeed in obtaining funding from any of the five judges. She said Cheek’d only had 1000 subscribers at that time. === Business card model === Cheek'd offered two plans, paid and free. For $25, subscribers got a set of 50 business cards that could be given out once someone caught their eye. Each card had a phrase, an online code, and a URL to the subscriber's account. Recipients could look up the giver's profile. In addition to purchasing cards, there was a $9.95 monthly membership fee. === Smartphone app === In 2015, the service's name changed from "Cheek'd" to "Cheekd". The new app used Bluetooth technology to alert users whenever a compatible user was within a 30-foot radius, instead of using cards. == Patent lawsuit == The original business card-based model for Cheekd had been claimed as a patented process by Lori Cheek, as U.S. patent 8,543,465. In September 2017, a complaint was filed, alleging that the idea was not original to Lori Cheek. Cheek responded, stating that the complaint was baseless, and a complete fabrication. The lawsuit Pirri v. Cheek was dismissed in a pre-trial conference in New York's Federal Court on April 5, 2018.
OpenNN
OpenNN (Open Neural Networks Library) is a software library written in the C++ programming language which implements neural networks, a main area of deep learning research. The library is open-source, licensed under the GNU Lesser General Public License. == Characteristics == The software implements any number of layers of non-linear processing units for supervised learning. This deep architecture allows the design of neural networks with universal approximation properties. Additionally, it allows multiprocessing programming by means of OpenMP, in order to increase computer performance. OpenNN contains machine learning algorithms as a bundle of functions. These can be embedded in other software tools, using an application programming interface, for the integration of the predictive analytics tasks. In this regard, a graphical user interface is missing but some functions can be supported by specific visualization tools. == History == The development started in 2003 at the International Center for Numerical Methods in Engineering, within the research project funded by the European Union called RAMFLOOD (Risk Assessment and Management of FLOODs). Then it continued as part of similar projects. OpenNN is being developed by the startup company Artelnics. == Applications == OpenNN is a general purpose artificial intelligence software package. It uses machine learning techniques for solving predictive analytics tasks in different fields. For instance, the library has been applied in the engineering, energy, or chemistry sectors.
Project Joshua Blue
Joshua Blue is a project under development by IBM that focuses on advancing the artificial intelligence field by designing and programming computers to emulate human mental functions. == Goals == According to researchers at IBM's Thomas J. Watson Research Center, the main goal of Joshua Blue is "to achieve cognitive flexibility that approaches human functioning". In short, IBM is aiming to design Joshua Blue to 'think like a human', mainly in terms of emotional thought. == How it will work == A model of Joshua Blue's learning pattern has been created. Similar to how young children learn human traits through interacting with their surroundings, Joshua Blue will acquire knowledge through external stimuli present in its environment. IBM believes that if computers evolve to learn in this way and then comprehend and analyze the knowledge gained using reason, computers could begin to possess a "mind", of sorts, capable of demonstrating complex social behaviors similar to those of humans. Thus far, IBM has revealed that Joshua Blue will be a computer with a network of wires and input nodes that function as a computer nervous system. This nervous system will be used by Joshua Blue to perceive affect or personal emotional feelings. Not only will this network of input nodes help Joshua Blue discover things physically, but it will also allow Joshua Blue to interpret the significance of events. The input nodes, or proprioceptors, will enable Joshua Blue to be aware of things that happen around itself, as well as recognize and attach meaning to the emotional effect produced by interacting with an object in a certain way. In addition, Joshua Blue's proprioceptors will function as pain and pleasure sensors, allowing Joshua Blue to employ a similar "reward and punishment" system that humans use to form behaviors.
Vivification
Vivification is an operation on a description logic knowledge base to improve performance of a semantic reasoner. Vivification replaces a disjunction of concepts C 1 ⊔ C 2 … ⊔ C n {\displaystyle C_{1}\sqcup C_{2}\ldots \sqcup C_{n}} by the least common subsumer of the concepts C 1 , C 2 , … C n {\displaystyle C_{1},C_{2},\ldots C_{n}} . The goal of this operation is to improve the performance of the reasoner by replacing a complex set of concepts with a single concept which subsumes the original concepts. For example, consider the example given in (Cohen 92): Suppose we have the concept PIANIST(Jill) ∨ ORGANIST(Jill) {\displaystyle {\textrm {PIANIST(Jill)}}\vee {\textrm {ORGANIST(Jill)}}} . This concept can be vivified into a simpler concept KEYBOARD-PLAYER(Jill) {\displaystyle {\textrm {KEYBOARD-PLAYER(Jill)}}} . This summarization leads to an approximation that may not be exactly equivalent to the original. == An approximation == Knowledge base vivification is not necessarily exact. If the reasoner is operating under the open world assumption we may get surprising results. In the previous example, if we replace the disjunction with the vivified concept, we will arrive at a surprising results. First, we find that the reasoner will no longer classify Jill as either a pianist or an organist. Even though ORGANIST {\displaystyle {\textrm {ORGANIST}}} and PIANIST {\displaystyle {\textrm {PIANIST}}} are the only two sub-classes, under the OWA we can no longer classify Jill as playing one or the other. The reason is that there may be another keyboard instrument (e.g. a harpsichord) that Jill plays but which does not have a specific subclass.
Facial age estimation
Facial age estimation is the use of artificial intelligence to estimate the age of a person based on their facial features. Computer vision techniques are used to analyse the facial features in the images of millions of people whose age is known and then deep learning is used to create an algorithm that tries to predict the age of an unknown person. The key use of the technology is to prevent access to age-restricted goods and services. Examples include restricting children from accessing internet pornography, checking that they meet a mandatory minimum age when registering for an account on social media, or preventing adults from accessing websites, online chat or games designed only for use by children. The technology is distinct from facial recognition systems as the software does not attempt to uniquely identify the individual. Researchers have applied neural networks for age estimation since at least 2010. == Evaluation == An ongoing study by the National Institute of Standards and Technology (NIST) entitled 'Face Analysis Technology Evaluation' seeks to establish the technical performance of prototype age estimation algorithms submitted by academic teams and software vendors including Brno University of Technology, Czech Technical University in Prague, Dermalog, IDEMIA, Incode Technologies Inc, Jumio, Nominder, Rank One Computing, Unissey and Yoti. == Public sector use == The UK government has explored using facial age estimation at the UK border as an alternative to bone X-rays and MRI scans when determining child status of asylum seekers. == Commercial use == Commercial users of facial age estimation include Instagram and OnlyFans. In January 2025, John Lewis & Partners announced that had started using the technology to check the age of people shopping for knives on its website, to comply with UK legislation to limit knife crime. In the UK, several supermarket chains have taken part in Home Office trials of the technology to automate the checking of a customer's age when buying age-restricted goods such as alcohol. UK legislation introduced in January 2025 mandates robust forms of age verification hosting adult content viewable in the UK by July 2025. Allowable methods include facial age estimation. == Criticism == Adam Schwartz, a lawyer for the Electronic Frontier Foundation, criticized the use of facial age estimation software, noting its inaccuracy especially in cases of minorities and women, as was found in NIST's 2024 report. Twenty organisations jointly under European Digital Rights called the practice a "systematic and invasive processing of young people's data" that risks discriminatory profiling.
Lumpers and splitters
Lumpers and splitters are opposing factions in any academic discipline that has to place individual examples into rigorously defined categories. The lumper–splitter problem occurs when there is the desire to create classifications and assign examples to them, for example, schools of literature, biological taxa, and so on. A "lumper" is a person who assigns examples broadly, judging that differences are not as important as signature similarities. A "splitter" makes precise definitions, and creates new categories to classify samples that differ in key ways. == Origin of the terms == The earliest known use of these terms was thought to be by Charles Darwin, in a letter to Joseph Dalton Hooker in 1857: "It is good to have hair-splitters & lumpers". But according to research done by the deputy director at NCSE, Glenn Branch, the credit is due to naturalist Edward Newman who wrote in 1845, "The time has arrived for discarding imaginary species, and the duty of doing this is as imperative as the admission of new ones when such are really discovered. The talents described under the respective names of 'hair-splitting' and 'lumping' are unquestionably yielding their power to the mightier power of Truth." They were then introduced more widely by George G. Simpson in his 1945 work The Principles of Classification and a Classification of Mammals. As he put it: splitters make very small units – their critics say that if they can tell two animals apart, they place them in different genera ... and if they cannot tell them apart, they place them in different species. ... Lumpers make large units – their critics say that if a carnivore is neither a dog nor a bear, they call it a cat. A later use can be found in the title of a 1969 paper "On lumpers and splitters ..." by the medical geneticist Victor McKusick. Reference to lumpers and splitters in the humanities appeared in a debate in 1975 between J. H. Hexter and Christopher Hill, in the Times Literary Supplement. It followed from Hexter's detailed review of Hill's book Change and Continuity in Seventeenth Century England, in which Hill developed Max Weber's argument that the rise of capitalism was facilitated by Calvinist Puritanism. Hexter objected to Hill's "mining" of sources to find evidence that supported his theories. Hexter argued that Hill plucked quotations from sources in a way that distorted their meaning. Hexter explained this as a mental habit that he called "lumping". According to him, "lumpers" rejected differences and chose to emphasise similarities. Any evidence that did not fit their arguments was ignored as aberrant. Splitters, by contrast, emphasised differences, and resisted simple schemes. While lumpers consistently tried to create coherent patterns, splitters preferred incoherent complexity. == Usage in various fields == === Biology === The categorisation and naming of a particular species should be regarded as a hypothesis about the evolutionary relationships and distinguishability of that group of organisms. As further information comes to hand, the hypothesis may be confirmed or refuted. Sometimes, especially in the past when communication was more difficult, taxonomists working in isolation have given two distinct names to individual organisms later identified as the same species. When two named species are agreed to be of the same species, the older species name is almost always retained dropping the newer species name honouring a convention known as "priority of nomenclature". This form of lumping is technically called synonymisation. Dividing a taxon into multiple, often new, taxa is called splitting. Taxonomists are often referred to as "lumpers" or "splitters" by their colleagues, depending on their personal approach to recognizing differences or commonalities between organisms. For example, the number of genera used in Pteridophyte Phylogeny Group I (PPG I) has proved controversial. PPG I uses 18 lycophyte and 319 fern genera. The earlier system put forward by Smith et al. (2006) had suggested a range of 274 to 312 genera for ferns alone. By contrast, the system of Christenhusz & Chase (2014) used 5 lycophyte and about 212 fern genera. The number of fern genera was further reduced to 207 in a subsequent publication. Defending PPG I, Schuettpelz et al. (2018) argue that the larger number of genera is a result of "the gradual accumulation of new collections and new data" and hence "a greater appreciation of fern diversity and ... an improved ability to distinguish taxa". They also argue that the number of species per genus in the PPG I system is already higher than in other groups of organisms (about 33 species per genus for ferns as opposed to about 22 species per genus for angiosperms) and that reducing the number of genera as Christenhusz and Chase propose yields the excessive number of about 50 species per genus for ferns. In response, Christenhusz and Chase (2018) argue that the excessive splitting of genera destabilises the usage of names and will lead to greater instability in future, and that the highly split genera have few if any characters that can be used to recognise them, making identification difficult, even to generic level. They further argue that comparing numbers of species per genus in different groups is "fundamentally meaningless". === History === In history, lumpers are those who tend to create broad definitions that cover large periods of time and many disciplines, whereas splitters want to assign names to tight groups of inter-relationships. Lumping tends to create a more and more unwieldy definition, with members having less and less mutually in common. This can lead to definitions which are little more than conventionalities, or groups which join fundamentally different examples. Splitting often leads to "distinctions without difference", ornate and fussy categories, and failure to see underlying similarities. For example, in the arts, "Romantic" can refer specifically to a period of German poetry roughly from 1780 to 1810, but would exclude the later work of Goethe, among other writers. In music it can mean every composer from Hummel through Rachmaninoff, plus many that came after. === Software modelling === Software engineering often proceeds by building models (sometimes known as model-driven architecture). A lumper is keen to generalise, and produces models with a small number of broadly defined objects. A splitter is reluctant to generalise, and produces models with a large number of narrowly defined objects. Conversion between the two styles is not necessarily symmetrical. For example, if error messages in two narrowly defined classes behave in the same way, the classes can be easily combined. But if some messages in a broad class behave differently, every object in the class must be examined before the class can be split. This illustrates the principle that "splits can be lumped more easily than lumps can be split". === Language classification === There is no agreement among historical linguists about what amount of evidence is needed for two languages to be safely classified in the same language family. For this reason, many proposed language families have had lumper–splitter controversies, including Altaic, Pama–Nyungan, Nilo-Saharan, and most of the larger families of the Americas. At a completely different level, the splitting of a mutually intelligible dialect continuum into different languages, or lumping them into one, is also an issue that continually comes up, though the consensus in contemporary linguistics is that there is no completely objective way to settle the question. Splitters regard the comparative method (meaning not comparison in general, but only reconstruction of a common ancestor or protolanguage) as the only valid proof of kinship, and consider genetic relatedness to be the question of interest. American linguists of recent decades tend to be splitters. Lumpers are more willing to admit techniques like mass lexical comparison or lexicostatistics, and mass typological comparison, and to tolerate the uncertainty of whether relationships found by these methods are the result of linguistic divergence (descent from common ancestor) or language convergence (borrowing). Much long-range comparison work has been from Russian linguists belonging to the Moscow School of Comparative Linguistics, most notably Vladislav Illich-Svitych and Sergei Starostin. In the United States, Greenberg and Ruhlen's work has been met with little acceptance from linguists. Earlier American linguists like Morris Swadesh and Edward Sapir also pursued large-scale classifications like Sapir's 1929 scheme for the Americas, accompanied by controversy similar to that today. === Religious studies === Paul F. Bradshaw suggests that the same principles of lumping and splitting apply to the study of early Christian liturgy. Lumpers, who tend to predominate in this field, try to find a single line of successive texts from the apostolic age to the