Photoacoustic imaging (PA) is based on the photoacoustic effect, in which optical absorption causes a rise in temperature, which causes a subsequent rise in pressure via thermo-elastic expansion. This pressure rise propagates through the tissue and is sensed via ultrasonic transducers. Due to the proportionality between the optical absorption, the rise in temperature, and the rise in pressure, the ultrasound pressure wave signal can be used to quantify the original optical energy deposition within the tissue. Photoacoustic imaging has applications of deep learning in both photoacoustic computed tomography (PACT) and photoacoustic microscopy (PAM). PACT utilizes wide-field optical excitation and an array of unfocused ultrasound transducers. Similar to other computed tomography methods, the sample is imaged at multiple view angles, which are then used to perform an inverse reconstruction algorithm based on the detection geometry (typically through universal backprojection, modified delay-and-sum, or time reversal ) to elicit the initial pressure distribution within the tissue. PAM on the other hand uses focused ultrasound detection combined with weakly focused optical excitation (acoustic resolution PAM or AR-PAM) or tightly focused optical excitation (optical resolution PAM or OR-PAM). PAM typically captures images point-by-point via a mechanical raster scanning pattern. At each scanned point, the acoustic time-of-flight provides axial resolution while the acoustic focusing yields lateral resolution. == Applications of deep learning in PACT == The first application of deep learning in PACT was by Reiter et al. in which a deep neural network was trained to learn spatial impulse responses and locate photoacoustic point sources. The resulting mean axial and lateral point location errors on 2,412 of their randomly selected test images were 0.28 mm and 0.37 mm respectively. After this initial implementation, the applications of deep learning in PACT have branched out primarily into removing artifacts from acoustic reflections, sparse sampling, limited-view, and limited-bandwidth. There has also been some recent work in PACT toward using deep learning for wavefront localization. There have been networks based on fusion of information from two different reconstructions to improve the reconstruction using deep learning fusion based networks. === Using deep learning to locate photoacoustic point sources === Traditional photoacoustic beamforming techniques modeled photoacoustic wave propagation by using detector array geometry and the time-of-flight to account for differences in the PA signal arrival time. However, this technique failed to account for reverberant acoustic signals caused by acoustic reflection, resulting in acoustic reflection artifacts that corrupt the true photoacoustic point source location information. In Reiter et al., a convolutional neural network (similar to a simple VGG-16 style architecture) was used that took pre-beamformed photoacoustic data as input and outputted a classification result specifying the 2-D point source location. ==== Deep learning for PA wavefront localization ==== Johnstonbaugh et al. was able to localize the source of photoacoustic wavefronts with a deep neural network. The network used was an encoder-decoder style convolutional neural network. The encoder-decoder network was made of residual convolution, upsampling, and high field-of-view convolution modules. A Nyquist convolution layer and differentiable spatial-to-numerical transform layer were also used within the architecture. Simulated PA wavefronts served as the input for training the model. To create the wavefronts, the forward simulation of light propagation was done with the NIRFast toolbox and the light-diffusion approximation, while the forward simulation of sound propagation was done with the K-Wave toolbox. The simulated wavefronts were subjected to different scattering mediums and Gaussian noise. The output for the network was an artifact free heat map of the targets axial and lateral position. The network had a mean error rate of less than 30 microns when localizing target below 40 mm and had a mean error rate of 1.06 mm for localizing targets between 40 mm and 60 mm. With a slight modification to the network, the model was able to accommodate multi target localization. A validation experiment was performed in which pencil lead was submerged into an intralipid solution at a depth of 32 mm. The network was able to localize the lead's position when the solution had a reduced scattering coefficient of 0, 5, 10, and 15 cm−1. The results of the network show improvements over standard delay-and-sum or frequency-domain beamforming algorithms and Johnstonbaugh proposes that this technology could be used for optical wavefront shaping, circulating melanoma cell detection, and real-time vascular surgeries. === Removing acoustic reflection artifacts (in the presence of multiple sources and channel noise) === Building on the work of Reiter et al., Allman et al. utilized a full VGG-16 architecture to locate point sources and remove reflection artifacts within raw photoacoustic channel data (in the presence of multiple sources and channel noise). This utilization of deep learning trained on simulated data produced in the MATLAB k-wave library, and then later reaffirmed their results on experimental data. === Ill-posed PACT reconstruction === In PACT, tomographic reconstruction is performed, in which the projections from multiple solid angles are combined to form an image. When reconstruction methods like filtered backprojection or time reversal, are ill-posed inverse problems due to sampling under the Nyquist-Shannon's sampling requirement or with limited-bandwidth/view, the resulting reconstruction contains image artifacts. Traditionally these artifacts were removed with slow iterative methods like total variation minimization, but the advent of deep learning approaches has opened a new avenue that utilizes a priori knowledge from network training to remove artifacts. In the deep learning methods that seek to remove these sparse sampling, limited-bandwidth, and limited-view artifacts, the typical workflow involves first performing the ill-posed reconstruction technique to transform the pre-beamformed data into a 2-D representation of the initial pressure distribution that contains artifacts. Then, a convolutional neural network (CNN) is trained to remove the artifacts, in order to produce an artifact-free representation of the ground truth initial pressure distribution. ==== Using deep learning to remove sparse sampling artifacts ==== When the density of uniform tomographic view angles is under what is prescribed by the Nyquist-Shannon's sampling theorem, it is said that the imaging system is performing sparse sampling. Sparse sampling typically occurs as a way of keeping production costs low and improving image acquisition speed. The typical network architectures used to remove these sparse sampling artifacts are U-net and Fully Dense (FD) U-net. Both of these architectures contain a compression and decompression phase. The compression phase learns to compress the image to a latent representation that lacks the imaging artifacts and other details. The decompression phase then combines with information passed by the residual connections in order to add back image details without adding in the details associated with the artifacts. FD U-net modifies the original U-net architecture by including dense blocks that allow layers to utilize information learned by previous layers within the dense block. Another technique was proposed using a simple CNN based architecture for removal of artifacts and improving the k-wave image reconstruction. ==== Removing limited-view artifacts with deep learning ==== When a region of partial solid angles are not captured, generally due to geometric limitations, the image acquisition is said to have limited-view. As illustrated by the experiments of Davoudi et al., limited-view corruptions can be directly observed as missing information in the frequency domain of the reconstructed image. Limited-view, similar to sparse sampling, makes the initial reconstruction algorithm ill-posed. Prior to deep learning, the limited-view problem was addressed with complex hardware such as acoustic deflectors and full ring-shaped transducer arrays, as well as solutions like compressed sensing, weighted factor, and iterative filtered backprojection. The result of this ill-posed reconstruction is imaging artifacts that can be removed by CNNs. The deep learning algorithms used to remove limited-view artifacts include U-net and FD U-net, as well as generative adversarial networks (GANs) and volumetric versions of U-net. One GAN implementation of note improved upon U-net by using U-net as a generator and VGG as a discriminator, with the Wasserstein metric and gradient penalty to stabilize training (WGAN-GP). ==== Pixel-wise interpolation
Colloquis
Colloquis, previously known as ActiveBuddy and Conversagent, was a company that created conversation-based interactive agents originally distributed via instant messaging platforms. The company had offices in New York, New York, and Sunnyvale, California. == History == Founded in 2000, the company was the brainchild of Robert Hoffer, Timothy Kay, and Peter Levitan. The idea for interactive agents (also known as Internet bots) came from the team's vision to add functionality to increasingly popular instant messaging services. The original implementation took shape as a word-based adventure game but quickly grew to include a wide range of database applications, including access to news, weather, stock information, movie times, Yellow Pages listings, and detailed sports data, as well as a variety of tools (calculators, translator, etc.). These various applications were bundled into one entity and launched as SmarterChild in 2001. SmarterChild acted as a showcase for the quick data access and possibilities for fun conversation that the company planned to turn into customized, niche-specific products. The rapid success of SmarterChild led to targeted promotional products for Radiohead, Austin Powers, The Sporting News, and others. ActiveBuddy sought to strengthen its hold on the interactive agent market for the future by filing for, and receiving, a controversial patent on their creation in 2002. The company also released the BuddyScript SDK, a free developer kit that allow programmers to design and launch their own interactive agents using ActiveBuddy's proprietary scripting language, in 2002. Ultimately, however, the decline in ad spending in 2001 and 2002 led to a shift in corporate strategy towards business focused Automated Service Agents, building products for clients including Cingular, Comcast and Cox Communications. The company subsequently changed its name from ActiveBuddy to Conversagent in 2003, and then again to Colloquis in 2006. Colloquis was purchased by Microsoft in October 2006.
Supertoroid
In geometry and computer graphics, a supertoroid or supertorus is usually understood to be a family of doughnut-like surfaces (technically, a topological torus) whose shape is defined by mathematical formulas similar to those that define the superellipsoids. The plural of "supertorus" is either supertori or supertoruses. The family was described and named by Alan Barr in 1994. Barr's supertoroids have been fairly popular in computer graphics as a convenient model for many objects, such as smooth frames for rectangular things. One quarter of a supertoroid can provide a smooth and seamless 90-degree joint between two superquadric cylinders. However, they are not algebraic surfaces (except in special cases). == Formulas == Alan Barr's supertoroids are defined by parametric equations similar to the trigonometric equations of the torus, except that the sine and cosine terms are raised to arbitrary powers. Namely, the generic point P(u, v) of the surface is given by P ( u , v ) = ( X ( u , v ) Y ( u , v ) Z ( u , v ) ) = ( ( a + C u s ) C v t ( b + C u s ) S v t S u s ) {\displaystyle P(u,v)=\left({\begin{array}{c}X(u,v)\\Y(u,v)\\Z(u,v)\end{array}}\right)=\left({\begin{array}{c}(a+C_{u}^{s})C_{v}^{t}\\(b+C_{u}^{s})S_{v}^{t}\\S_{u}^{s}\end{array}}\right)} where C θ ε = sgn ( cos θ ) | cos θ | ε , S θ ε = sgn ( sin θ ) | sin θ | ε , {\displaystyle {\begin{aligned}C_{\theta }^{\varepsilon }&=\operatorname {sgn} (\cos \theta )\,\left|\,\cos \theta \,\right|^{\varepsilon },\\S_{\theta }^{\varepsilon }&=\operatorname {sgn} (\sin \theta )\ \left|\,\sin \theta \ \right|^{\varepsilon },\end{aligned}}} sgn is the sign function, and the parameters u, v range from 0 to 360 degrees (0 to 2π radians). In these formulas, the parameter s > 0 controls the "squareness" of the vertical sections, t > 0 controls the squareness of the horizontal sections, and a, b ≥ 1 are the major radii in the x and y directions. With s = t = 1 and a = b = R one obtains the ordinary torus with major radius R and minor radius 1, with the center at the origin and rotational symmetry about the z-axis. In general, the supertorus defined as above spans the intervals: − ( a + 1 ) ≤ x ≤ + ( a + 1 ) − ( b + 1 ) ≤ y ≤ + ( b + 1 ) − 1 ≤ z ≤ + 1 {\displaystyle {\begin{array}{rcccl}-(a+1)&\leq &x&\leq &+(a+1)\\[4pt]-(b+1)&\leq &y&\leq &+(b+1)\\[4pt]-1&\leq &z&\leq &+1\end{array}}} The whole shape is symmetric about the planes x = 0, y = 0, and z = 0. The hole runs in the z direction and spans the intervals − ( a − 1 ) ≤ x ≤ + ( a − 1 ) − ( b − 1 ) ≤ y ≤ + ( b − 1 ) − ∞ ≤ z ≤ + ∞ {\displaystyle {\begin{array}{rcccl}-(a-1)&\leq &x&\leq &+(a-1)\\[4pt]-(b-1)&\leq &y&\leq &+(b-1)\\[4pt]-\infty &\leq &z&\leq &+\infty \end{array}}} A curve of constant u on this surface is a horizontal Lamé curve with exponent 2 t , {\displaystyle {\tfrac {2}{t}},} scaled in x and y and displaced in z. A curve of constant v, projected on the plane x = 0 or y = 0, is a Lamé curve with exponent 2 s , {\displaystyle {\tfrac {2}{s}},} scaled and horizontally shifted. If v = 0, the curve is planar and spans the intervals: a − 1 ≤ x ≤ a + 1 − 1 ≤ z ≤ + 1 {\displaystyle {\begin{array}{rcccl}a-1&\leq &x&\leq &a+1\\[4pt]-1&\leq &z&\leq &+1\end{array}}} and similarly if v = 90°, 180°, 270°. The curve is also planar if a = b. In general, if a ≠ b and v is not a multiple of 90 degrees, the curve of constant v will not be planar; and, conversely, a vertical plane section of the supertorus will not be a Lamé curve. The basic supertoroid shape defined above is often modified by non-uniform scaling to yield supertoroids of specific width, length, and vertical thickness. == Plotting code == The following GNU Octave code generates plots of a supertorus:
Colour banding
Colour banding is a subtle form of posterisation in digital images, caused by the colour of each pixel being rounded to the nearest of the digital colour levels. While posterisation is often done for artistic effect, colour banding is an undesired artefact. In 24-bit colour modes, 8 bits per channel is usually considered sufficient to render images in Rec. 709 or sRGB. However the eye can see the difference between the colour levels, especially when there is a sharp border between two large areas of adjacent colour levels. This will happen with gradual gradients (like sunsets, dawns or clear blue skies), and also when blurring an image a large amount. Colour banding is more noticeable with fewer bits per pixel (BPP) at 16–256 colours (4–8 BPP), where there are fewer shades with a larger difference between them. The appearance of colour banding is exaggerated by the Mach bands effect. Possible solutions include the introduction of dithering and increasing the number of bits per colour channel. Because the banding comes from limitations in the presentation of the image, blurring the image does not fix this unless the image BPP is higher than the original.
List of security-focused operating systems
This is a list of operating systems specifically focused on security. Similar concepts include security-evaluated operating systems that have achieved certification from an auditing organization, and trusted operating systems that provide sufficient support for multilevel security and evidence of correctness to meet a particular set of requirements. == Linux == === Android-based === GrapheneOS is a security-focused, Android-based mobile OS that uses a hardened kernel, C library, custom memory allocator (hardened_malloc), and a hardened Chromium-based browser named Vanadium. It also offers privacy/security features, such as Duress PIN/Password or disabling the USB-C port at a driver/hardware level to avoid exploitation. It deploys exploit mitigations such as hardware-based memory tagging, secure app spawning, restricted dynamic code loading, and more. === Debian-based === Linux Kodachi is a security-focused operating system. Tails is aimed at preserving privacy and anonymity. KickSecure is a security-focused Linux distribution that aims to be "hardened by default". It uses network hardening, kernel hardening, Strong Linux User Account Isolation, better randomness, root access restrictions, and app-specific hardening. Whonix is an anonymity focused operating system based on KickSecure. It consists of two virtual machines, And all communications are routed through Tor. === Other Linux distributions === Alpine Linux is designed to be small, simple, and secure. It uses musl, BusyBox, and OpenRC instead of the more commonly used glibc, GNU Core Utilities, and systemd. Owl - Openwall GNU/Linux, a security-enhanced Linux distribution for servers. Secureblue, a Fedora Silverblue based distro that uses a hardened kernel, custom memory allocator (hardened_malloc), Trivalent, a security-focused, Chromium-based browser inspired by Vanadium, and many other exploit mitigations. == BSD == OpenBSD is a Unix-like operating system that emphasizes portability, standardization, correctness, proactive security, and integrated cryptography. == Xen == Qubes OS aims to provide security through isolation. Isolation is provided through the use of virtualization technology. This allows the segmentation of applications into secure virtual machines.
Taimi
Taimi ( TAY-mee) is a dating app that caters to the LGBTQI+ community. The network matches its registered users based on their selected preferences and location. Originally an online dating service for gay men, by 2022 Taimi had become an app for all members of the LGBTQI+ community. It operates in more than 138 countries, including the US, UK, the Netherlands, Spain, Central and South America, Ukraine, and other European and Asian countries. Taimi runs on iOS and Android. The mobile app has a free and subscription-based premium version and offers a number of services for communication, including live streaming, chatting, and video calling. There is also an active blog that regularly posts articles and news about events of interest to the LGBTQ+ community. The application does not provide for non-Google e-mail log option, either phone number or Facebook account, during the registration process. The data controller for the non EU/UK users is based in a company, called Social Impact Inc., with its registered address at 1180 North Town Center Drive Suite 100, Las Vegas, Nevada, 89144, United States of America. == History == Taimi was launched in 2017 by Social Impact, Inc. in Las Vegas. Its founder, Alex Pasykov, originally called the app "Tame Me," a name that gradually morphed into Taimi. Over time, Taimi expanded into other countries, and expanding its reach to the LGBTQ+ community, so that, by 2022, it was fully inclusive of the entire queer community. In November 2020 the app was redesigned, with a new interface, branding, and logo. As of 2024, there are over 25 million registered users of Taimi worldwide. Pasykov states that he is an ally of the LGBTQ+ community and that he is focused on, among other things, partnering with NGOs to fight Homophobia and "regressive policies and laws" that negatively impact the community. == Features == Users register on the app and complete a profile, including personal information and preferences for compatibility, dating style, and relationship goals. An algorithm then finds and presents recommendations that a user accepts or rejects. Users are then free to chat via text or video with people they have connected with. Safety and security features include a two-step authentication process and an automated account verification along with a clear reporting system when breaches or policy violations occur. User responses to new features and policies drive changes and modifications that are made to all aspects of the site. == Partnerships and Collaborations == Taimi has a long history of collaborations and partnerships in Pride events, both in the US and abroad, including fund-raising efforts. Taimi has partnered with Rakuten Viber to create a bot focused on educating its members on key LGBTQ+ topics and to allow queer Viber users to connect. In 2023, Taimi collaborated with the Known Agency in an "America the Beautiful" campaign to shine a spotlight on current anti-LGBTQ+ policies and laws in a number of US states, and to counter these by highlighting the values and freedoms upon which America was founded. The campaign was nominated for The Drum Awards in the category "OOH For Good" and honored with the ANA Multicultural Excellence Award. Taimi also partnered with Goodparts, a queer-owned and operated retailer, in a "Body Beautiful" campaign focused on love and acceptance of all body types. In this campaign, well-known LGBTQ+ artists are providing artwork for Goodpart's product packaging. From October 31 to December 13, 2023, Taimi showed the "Taimi Moments" video, created in collaboration with Raygun Agency, on large screens between performances of LGBTQ+ artists Doja Cat, Ice Spice, and Doechii on their Scarlet Tour. In spring 2024, Taimi launched Queer Paradise, a series of live events in Southern California to celebrate diversity, sexual exploration, and dating fluidity. Each event in the series was curated to give the full spectrum of groups within the LGBTQ+ community a space to express their authentic selves. Taimi's partners for Queer Paradise include Hawtmess Productions, Eden Entertainment Group, Hump Events, Girls Gays & Theys, Damn Good Dyke Nights, and Gaybors Agency. In summer 2024, with support from GLAAD, Taimi has updated features and self-expression tools to better serve the LGBTQ+ people seeking connection in the app. Taimi allowed members to select multiple sexualities, unified the list of sexualities across all genders, added more pronoun options, and created a more inclusive and improved list of subcategories for non-binary users. Also, in summer 2024, Taimi has partnered with gender-affirming underwear brand Urbody to release a capsule collection. Focused on gender inclusivity and sexual fluidity, the capsule collection includes a range of underwear and compression tops intended to promote "joy, self-love and empowerment."
Glow (app)
Glow is a fertility awareness and period-tracking app. It is part of a suite of mobile apps focused on women's reproductive health and childcare, which includes Eve by Glow (a dedicated period tracker), Glow Nurture (a pregnancy tracker), and Glow Baby (a baby development tracker). The Glow company also operates an online shop that sells several fertility-related products, including ovulation test strips, pregnancy tests, and wearable breast pumps. In 2024, Glow was reported to have approximately 25 million users across its various apps and community message boards. == History == Glow debuted in August 2013 as an iOS app. It was founded by Michael Huang and Max Levchin and launched with $6 million in Series A funding from venture capital firms Founders Fund and Andreesen Horowitz. In 2014, Glow raised an additional $17 million in Series B funding, with Formation 8 joining existing investors. In 2015, Glow launched Ruby, an app dedicated to sexual health. That year, Wired reported that the company had added features to their apps allowing men to monitor their fertility. Glow subsequently released an additional set of apps focused on pregnancy tracking and infant development. In 2016, Glow reported that it had a total of approximately 3 million users; by 2018, this had grown to 15 million. Vox described it as one of the “big two” period and fertility tracking apps and the one that had started the “boom” in the femtech space. == Application and features == Glow was initially described as a fertility application that applied data-driven methods to menstrual and ovulation tracking. Core features include cycle logging, ovulation prediction, and symptom tracking. The app also provides educational content related to reproductive health and childcare, as well as a set of online message boards that allow individuals to share experiences and seek peer support. == Privacy and legal issues == Glow has received significant media attention for its privacy and security practices. In 2016, Consumer Reports identified potential exploits in the Glow app that they claimed could have exposed private user data to hackers. Glow subsequently reported that it had fixed the vulnerabilities and told The Washington Post they had no evidence that user data had been compromised. In September 2020, the California Attorney General announced a settlement with Glow related to Consumer Reports’ findings, which included a $250,000 civil penalty. Following the US Supreme Court's 2022 Dobbs v. Jackson ruling, which legalized state-level bans on abortion, Glow (and other fertility trackers, such as Clue and Flo) came under additional scrutiny over concerns that user data on abortions could be reported to law enforcement. After this surge of media interest, a research team affiliated with the University of New South Wales conducted an investigation into the privacy practices of several popular fertility apps, including Glow. Their review of Glow was mixed, noting that they provided several privacy settings and de-identified sensitive data, but that user information could still be disclosed in the future if the app was sold. Glow rejected that claim, telling the Australian Associated Press that it "did not share" personal data. The company also cited several internal security measures it had implemented and its apps' offline data protection setting, which allows users to permanently delete their health-related data. == Reception == In 2014, Fast Company reported that 20,000 women had used Glow to conceive. Later that year, The Guardian included Glow Nurture on its list of the best iPhone apps of 2014. Media coverage often praised Glow's array of menstrual tracking options, although some reviews also noted that fertility apps are not birth control tools and cautioned against relying on them for that purpose. In 2019, Cosmopolitan singled Glow's community of users as one of its standout features.