An electronic lab notebook or electronic laboratory notebook (ELN) is a computer program designed to replace paper laboratory notebooks. Lab notebooks in general are used by scientists, engineers, and technicians to document research, experiments, and procedures performed in a laboratory. A lab notebook is often maintained to be a legal document and may be used in a court of law as evidence. Similar to an inventor's notebook, the lab notebook is also often referred to in patent prosecution and intellectual property litigation. Electronic lab notebooks offer many benefits to the user as well as organizations; they are easier to search upon, simplify data copying and backups, and support collaboration amongst many users. ELNs can have fine-grained access controls, and can be more secure than their paper counterparts. They also allow the direct incorporation of data from instruments, replacing the practice of printing out data to be stapled into a paper notebook. == Types == ELNs can be divided into two categories: "Specific ELNs" contain features designed to work with specific applications, scientific instrumentation or data types. "Cross-disciplinary ELNs" or "Generic ELNs" are designed to support access to all data and information that needs to be recorded in a lab notebook. Lab Platforms that combine an ELN, LIMS, and scientific data management together, all-in-one configurable software environment. Solutions range from specialized programs designed from the ground up for use as an ELN, to modifications or direct use of more general programs. Examples of using more general software as an ELN include using OpenWetWare, a MediaWiki install (running the same software that Wikipedia uses), WordPress, or the use of general note taking software such as OneNote as an ELN. ELN's come in many different forms. They can be standalone programs, use a client-server model, or be entirely web-based. Some use a lab-notebook approach, others resemble a blog. ELNs are embracing artificial intelligence and LLM technology to provide scientific AI chat assistants. A good many variations on the "ELN" acronym have appeared. Differences between systems with different names are often subtle, with considerable functional overlap between them. Examples include "ERN" (Electronic Research Notebook), "ERMS" (Electronic Resource (or Research or Records) Management System (or Software) and SDMS (Scientific Data (or Document) Management System (or Software). Ultimately, these types of systems all strive to do the same thing: Capture, record, centralize and protect scientific data in a way that is highly searchable, historically accurate, and legally stringent, and which also promotes secure collaboration, greater efficiency, reduced mistakes and lowered total research costs. == Objectives == A good electronic laboratory notebook should offer a secure environment to protect the integrity of both data and process, whilst also affording the flexibility to adopt new processes or changes to existing processes without recourse to further software development. The package architecture should be a modular design, so as to offer the benefit of minimizing validation costs of any subsequent changes that you may wish to make in the future as your needs change. A good electronic laboratory notebook should be an "out of the box" solution that, as standard, has fully configurable forms to comply with the requirements of regulated analytical groups through to a sophisticated ELN for inclusion of structures, spectra, chromatograms, pictures, text, etc. where a preconfigured form is less appropriate. All data within the system may be stored in a database (e.g. MySQL, MS-SQL, Oracle) and be fully searchable. The system should enable data to be collected, stored and retrieved through any combination of forms or ELN that best meets the requirements of the user. The application should enable secure forms to be generated that accept laboratory data input via PCs and/or laptops / palmtops, and should be directly linked to electronic devices such as laboratory balances, pH meters, etc. Networked or wireless communications should be accommodated for by the package which will allow data to be interrogated, tabulated, checked, approved, stored and archived to comply with the latest regulatory guidance and legislation. A system should also include a scheduling option for routine procedures such as equipment qualification and study related timelines. It should include configurable qualification requirements to automatically verify that instruments have been cleaned and calibrated within a specified time period, that reagents have been quality-checked and have not expired, and that workers are trained and authorized to use the equipment and perform the procedures. == Regulatory and legal aspects == The laboratory accreditation criteria found in the ISO 17025 standard needs to be considered for the protection and computer backup of electronic records. These criteria can be found specifically in clause 4.13.1.4 of the standard. Electronic lab notebooks used for development or research in regulated industries, such as medical devices or pharmaceuticals, are expected to comply with FDA regulations related to software validation. The purpose of the regulations is to ensure the integrity of the entries in terms of time, authorship, and content. Unlike ELNs for patent protection, FDA is not concerned with patent interference proceedings, but is concerned with avoidance of falsification. Typical provisions related to software validation are included in the medical device regulations at 21 CFR 820 (et seq.) and Title 21 CFR Part 11. Essentially, the requirements are that the software has been designed and implemented to be suitable for its intended purposes. Evidence to show that this is the case is often provided by a Software Requirements Specification (SRS) setting forth the intended uses and the needs that the ELN will meet; one or more testing protocols that, when followed, demonstrate that the ELN meets the requirements of the specification and that the requirements are satisfied under worst-case conditions. Security, audit trails, prevention of unauthorized changes without substantial collusion of otherwise independent personnel (i.e., those having no interest in the content of the ELN such as independent quality unit personnel) and similar tests are fundamental. Finally, one or more reports demonstrating the results of the testing in accordance with the predefined protocols are required prior to release of the ELN software for use. If the reports show that the software failed to satisfy any of the SRS requirements, then corrective and preventive action ("CAPA") must be undertaken and documented. Such CAPA may extend to minor software revisions, or changes in architecture or major revisions. CAPA activities need to be documented as well. Aside from the requirements to follow such steps for regulated industry, such an approach is generally a good practice in terms of development and release of any software to assure its quality and fitness for use. There are standards related to software development and testing that can be applied (see ref.).
Irwin Sobel
Irwin Sobel (born September 12, 1940) is a scientist and researcher in digital image processing. == Biography == Irwin Sobel was born in New York City. He graduated from MIT in 1961 and completed his Ph.D. research at the Stanford Artificial Intelligence Project (SAIL) with thesis Camera Models and Machine Perception. His Ph.D. advisor was Jerome A. Feldman. Starting in 1973, he spent nine years doing postdoctoral research at Columbia University. After 1982, he worked as a Senior Researcher at HP Labs. == Sobel operator == In 1968, Sobel gave a talk entitled "An Isotropic 3x3 Image Gradient Operator" at SAIL; this method became known as the Sobel operator. It was developed jointly with a colleague, Gary Feldman, also at SAIL.
Chris Olah
Christopher Olah (born 1992 or 1993) is a Canadian machine learning researcher and a co-founder of Anthropic. He is known for his work on neural network interpretability, particularly mechanistic interpretability, and for research and tools that visualise internal representations in neural networks. In 2025, Forbes reported he had become a billionaire due to his ownership in Anthropic. == Early life and education == Olah was born in Canada. According to Wired, he left university at age 18 without earning a degree and later received a Thiel Fellowship, which supported him in pursuing independent work. == Career == Olah has worked on interpretability research at Google Brain, OpenAI, and Anthropic. Time called him one of the pioneers of mechanistic interpretability and noted that he pursued this research line first at Google, then at OpenAI, and later at Anthropic, which he co-founded. Wired reported that Olah was involved in neural network visualisation work including DeepDream in 2015, as part of efforts to better understand what neural networks learn. Later coverage linked him to more structured interpretability approaches such as "activation atlases". The Verge covered activation atlases as a collaboration between Google and OpenAI researchers to help inspect neural network representations. At Anthropic, Olah has been identified in major press coverage as leading interpretability work aimed at mapping internal "features" in large language models and relating interpretability findings to AI safety. Quanta Magazine has also quoted Olah in reporting on interpretability and the internal structure of modern language models. Time included Olah in its TIME100 AI list in 2024. === Vatican address on AI ethics === On May 25, 2026, Olah spoke at the Vatican during the official presentation of Magnifica Humanitas, the first encyclical of Pope Leo XIV, which addresses artificial intelligence and human dignity. Olah said AI could lead to large-scale displacement of human labor and exacerbate global inequality. He said the commercial and geopolitical incentives driving frontier AI labs often conflict with the public good, and described AI systems as "grown" rather than strictly engineered. Olah called for external moral oversight from religious institutions, scholars, and civil society to hold the technology sector accountable.
Business rules engine
A business rules engine is a software system that executes one or more business rules in a runtime production environment. The rules might come from legal regulation ("An employee can be fired for any reason or no reason but not for an illegal reason"), company policy ("All customers that spend more than $100 at one time will receive a 10% discount"), or other sources. A business rule system enables these company policies and other operational decisions to be defined, tested, executed and maintained separately from application code. Rule engines typically support rules, facts, priority (score), mutual exclusion, preconditions, and other functions. Rule engine software is commonly provided as a component of a business rule management system which, among other functions, provides the ability to: register, define, classify, and manage all the rules, verify consistency of rules definitions (”Gold-level customers are eligible for free shipping when order quantity > 10” and “maximum order quantity for Silver-level customers = 15” ), define the relationships between different rules, and relate some of these rules to IT applications that are affected or need to enforce one or more of the rules. == IT use case == In any IT application, business rules can change more frequently than other parts of the application code. Rules engines or inference engines serve as pluggable software components which execute business rules that a business rules approach has externalized or separated from application code. This externalization or separation allows business users to modify the rules without the need for IT intervention. The system as a whole becomes more easily adaptable with such external business rules, but this does not preclude the usual requirements of QA and other testing. == History == An article in Computerworld traces rules engines to the early 1990s and to products from the likes of Pegasystems, Fair Isaac Corp, ILOG and eMerge from Sapiens. == Design strategies == Many organizations' rules efforts combine aspects of what is generally considered workflow design with traditional rule design. This failure to separate the two approaches can lead to problems with the ability to re-use and control both business rules and workflows. Design approaches that avoid this quandary separate the role of business rules and workflows as follows: Business rules produce knowledge; Workflows perform business work. Concretely, that means that a business rule may do things like detect that a business situation has occurred and raise a business event (typically carried via a messaging infrastructure) or create higher level business knowledge (e.g., evaluating the series of organizational, product, and regulatory-based rules concerning whether or not a loan meets underwriting criteria). On the other hand, a workflow would respond to an event that indicated something such as the overloading of a routing point by initiating a series of activities. This separation is important because the same business judgment (mortgage meets underwriting criteria) or business event (router is overloaded) can be reacted to by many different workflows. Embedding the work done in response to rule-driven knowledge creation into the rule itself greatly reduces the ability of business rules to be reused across an organization because it makes them work-flow specific. To create an architecture that employs a business rules engine it is essential to establish the integration between a BPM (Business Process Management) and a BRM (Business Rules Management) platform that is based upon processes responding to events or examining business judgments that are defined by business rules. There are some products in the marketplace that provide this integration natively. In other situations this type of abstraction and integration will have to be developed within a particular project or organization. Most Java-based rules engines provide a technical call-level interface, based on the JSR-94 application programming interface (API) standard, in order to allow for integration with different applications, and many rule engines allow for service-oriented integrations through Web-based standards such as WSDL and SOAP. Most rule engines provide the ability to develop a data abstraction that represents the business entities and relationships that rules should be written against. This business entity model can typically be populated from a variety of sources including XML, POJOs, flat files, etc. There is no standard language for writing the rules themselves. Many engines use a Java-like syntax, while some allow the definition of custom business-friendly languages. Most rules engines function as a callable library. However, it is becoming more popular for them to run as a generic process akin to the way that RDBMSs behave. Most engines treat rules as a configuration to be loaded into their process instance, although some are actually code generators for the whole rule execution instance and others allow the user to choose. == Types of rule engines == There are a number of different types of rule engines. These types (generally) differ in how Rules are scheduled for execution. Most rules engines used by businesses are forward chaining, which can be further divided into two classes: The first class processes so-called production/inference rules. These types of rules are used to represent behaviors of the type IF condition THEN action. For example, such a rule could answer the question: "Should this customer be allowed a mortgage?" by executing rules of the form "IF some-condition THEN allow-customer-a-mortgage". The other type of rule engine processes so-called reaction/Event condition action rules. The reactive rule engines detect and react to incoming events and process event patterns. For example, a reactive rule engine could be used to alert a manager when certain items are out of stock. The biggest difference between these types is that production rule engines execute when a user or application invokes them, usually in a stateless manner. A reactive rule engine reacts automatically when events occur, usually in a stateful manner. Many (and indeed most) popular commercial rule engines have both production and reaction rule capabilities, although they might emphasize one class over another. For example, most business rules engines are primarily production rules engines, whereas complex event processing rules engines emphasize reaction rules. In addition, some rules engines support backward chaining. In this case a rules engine seeks to resolve the facts to fit a particular goal. It is often referred to as being goal driven because it tries to determine if something exists based on existing information. Another kind of rule engine automatically switches between back- and forward-chaining several times during a reasoning run, e.g. the Internet Business Logic system, which can be found by searching the web. A fourth class of rules engine might be called a deterministic engine. These rules engines may forgo both forward chaining and backward chaining, and instead utilize domain-specific language approaches to better describe policy. This approach is often easier to implement and maintain, and provides performance advantages over forward or backward chaining systems. There are some circumstance where fuzzy logic based inference may be more appropriate, where heuristics are used in rule processing, rather than Boolean rules. Examples might include customer classification, missing data inference, customer value calculations, etc. The DARL language and the associated inference engine and editors is an example of this approach. == Rules engines for access control / authorization == One common use case for rules engines is standardized access control to applications. OASIS defines a rules engine architecture and standard dedicated to access control called XACML (eXtensible Access Control Markup Language). One key difference between a XACML rule engine and a business rule engine is the fact that a XACML rule engine is stateless and cannot change the state of any data. The XACML rule engine, called a Policy Decision Point (PDP), expects a binary Yes/No question e.g. "Can Alice view document D?" and returns a decision e.g. Permit / deny.
Cortica
Headquartered in Tel Aviv Cortica utilizes unsupervised learning methods to recognize and analyze digital images and video. The technology developed by the Cortica team is based on research of the function of the human brain. == Company Founding == Cortica was founded in 2007 by Igal Raichelgauz, Karina Odinaev and Yehoshua Zeevi. Together, the founders developed the company’s core technology while at Technion – Israel Institute of Technology. By combining discoveries in neuroscience with developments in computer programming, the team created technology that possesses the ability to interpret large amounts of visual data with increased accuracy. This technology, called Image2Text, is based on the founders’ work in digitally replicating cortical neural networks’ ability to identify complex patterns within massive quantities of ambiguous and noisy data. Cortica’s offerings have application in the automotive industry, media industries, as well as the smart city and medical industries. Industry experts suggest that the self-driving automotive industry alone will be worth upwards of $7 trillion while each connected car is expected to generate 4,000 GB of data per day. Beyond that, industry analysts expect the proliferation of surveillance cameras to continue leading to an expected 2,500 Petabytes of data being generated daily by new surveillance cameras. Cortica operates in these high scale industries. The company currently employs professionals from many domains including AI researchers as well as veterans of intelligence units within the Israeli Defense Forces. == Research and Technology == In 2006, Founders Raichelgauz, Odinaev, and Zeevi shared their findings with the 28th IEEE EMBS Annual International Conference in New York in a paper titled, “Natural Signal Classification by Neural Cliques and Phase-Locked Attractors”. That same year, the team also published “Cliques in Neural Ensembles as Perception Carriers" CB Insights recently identified Cortica as the number one patent holder among AI companies. Cortica is researching to develop a machine-learning driving system which can identify objects and pedestrians. Connecting to it, Elon Musk has been rumored to partner with Cortica for his electric car company, Tesla. However, Tesla denies it stating that Musk did not discuss a collaboration with artificial intelligence firm Cortica. == Funding == Cortica raised $7 million in its Series A funding round, announced in August 2012. Investors included Horizons Ventures (the investment firm of Hong Kong billionaire Li Ka-Shing), and Ynon Kreiz, the former chairman and CEO of the Endemol Group. In May 2013, it was announced that Cortica had raised $1.5 million from Russian firm Mail.ru Group. It later transpired that this was a part of Cortica's Series B funding round for $6.4 million, announced in June 2013. The round was led by Horizons Ventures, with participation from the Russian firm Mail.ru Group and other angel investors. In its fourth funding round, Cortica has raised $20 million, bringing the total investments to $38 million. According to a report from The Israeli lead Daily economic newspaper, TheMarker, the fourth round was led by a strategic Chinese investor who will probably help the company expand into the Asian market. == Media coverage == GigaOm listed Cortica as one of the top deep learning startups in a November 2013 article surveying the field, along with AlchemyAPI, Ersatz, and Semantria. Business Insider ranked Cortica as one of the coolest tech companies in Israel. CB Insights has identified Cortica as the top patent holding AI company. In 2017 several leading automotive media outlets covered the launch of Cortica's automotive business unit
Graphics
Graphics (from Ancient Greek γραφικός (graphikós) 'pertaining to drawing, painting, writing, etc.') are visual images or designs on some surface, such as a wall, canvas, screen, paper, or stone, to inform, illustrate, or entertain. In contemporary usage, it includes a pictorial representation of data, as in design and manufacture, in typesetting and the graphic arts, and in educational and recreational software. Images that are generated by a computer are called computer graphics. Examples are photographs, drawings, line art, mathematical graphs, line graphs, charts, diagrams, typography, numbers, symbols, geometric designs, maps, engineering drawings, or other images. Graphics often combine text, illustration, and color. Graphic design may consist of the deliberate selection, creation, or arrangement of typography alone, as in a brochure, flyer, poster, web site, or book without any other element. The objective can be clarity or effective communication, association with other cultural elements, or merely the creation of a distinctive style. Graphics can be functional or artistic. The latter can be a recorded version, such as a photograph, or an interpretation by a scientist to highlight essential features, or an artist, in which case the distinction with imaginary graphics may become blurred. It can also be used for architecture. == History == The earliest graphics known to anthropologists studying prehistoric periods are cave paintings and markings on boulders, bone, ivory, and antlers, which were created during the Upper Palaeolithic period from 40,000 to 10,000 B.C. or earlier. Many of these were found to record astronomical, seasonal, and chronological details. Some of the earliest graphics and drawings are known to the modern world, from almost 6,000 years ago, are that of engraved stone tablets and ceramic cylinder seals, marking the beginning of the historical periods and the keeping of records for accounting and inventory purposes. Records from Egypt predate these and papyrus was used by the Egyptians as a material on which to plan the building of pyramids; they also used slabs of limestone and wood. From 600 to 250 BC, the Greeks played a major role in geometry. They used graphics to represent their mathematical theories such as the Circle Theorem and the Pythagorean theorem. In art, "graphics" is often used to distinguish work in a monotone and made up of lines, as opposed to painting. === Drawing === Drawing generally involves making marks on a surface by applying pressure from a tool or moving a tool across a surface. In which a tool is always used as if there were no tools it would be art. Graphical drawing is an instrumental guided drawing. === Printmaking === Woodblock printing, including images is first seen in China after paper was invented (about A.D. 105). In the West, the main techniques have been woodcut, engraving and etching, but there are many others. ==== Etching ==== Etching is an intaglio method of printmaking in which the image is incised into the surface of a metal plate using an acid. The acid eats the metal, leaving behind roughened areas, or, if the surface exposed to the acid is very thin, burning a line into the plate. The use of the process in printmaking is believed to have been invented by Daniel Hopfer (c. 1470–1536) of Augsburg, Germany, who decorated armour in this way. Etching is also used in the manufacturing of printed circuit boards and semiconductor devices. === Line art === Line art is a rather non-specific term sometimes used for any image that consists of distinct straight and curved lines placed against a (usually plain) background, without gradations in shade (darkness) or hue (color) to represent two-dimensional or three-dimensional objects. Line art is usually monochromatic, although lines may be of different colors. === Illustration === An illustration is a visual representation such as a drawing, painting, photograph or other work of art that stresses the subject more than form. The aim of an illustration is to elucidate or decorate a story, poem or piece of textual information (such as a newspaper article), traditionally by providing a visual representation of something described in the text. The editorial cartoon, also known as a political cartoon, is an illustration containing a political or social message. Illustrations can be used to display a wide range of subject matter and serve a variety of functions, such as: giving faces to characters in a story displaying a number of examples of an item described in an academic textbook (e.g. A Typology) visualizing step-wise sets of instructions in a technical manual communicating subtle thematic tone in a narrative linking brands to the ideas of human expression, individuality, and creativity making a reader laugh or smile for fun (to make laugh) funny === Graphs === A graph or chart is a graphic that represents tabular or numeric data. Charts are often used to make it easier to understand large quantities of data and the relationships between different parts of the data. === Diagrams === A diagram is a simplified and structured visual representation of concepts, ideas, constructions, relations, statistical data, etc., used to visualize and clarify the topic. === Symbols === A symbol, in its basic sense, is a representation of a concept or quantity; i.e., an idea, object, concept, quality, etc. In more psychological and philosophical terms, all concepts are symbolic in nature, and representations for these concepts are simply token artifacts that are allegorical to (but do not directly codify) a symbolic meaning, or symbolism. === Maps === A map is a simplified depiction of a space, a navigational aid which highlights relations between objects within that space. Usually, a map is a two-dimensional, geometrically accurate representation of a three-dimensional space. One of the first 'modern' maps was made by Waldseemüller. === Photography === One difference between photography and other forms of graphics is that a photographer, in principle, just records a single moment in reality, with seemingly no interpretation. However, a photographer can choose the field of view and angle, and may also use other techniques, such as various lenses to choose the view or filters to change the colors. In recent times, digital photography has opened the way to an infinite number of fast, but strong, manipulations. Even in the early days of photography, there was controversy over photographs of enacted scenes that were presented as 'real life' (especially in war photography, where it can be very difficult to record the original events). Shifting the viewer's eyes ever so slightly with simple pinpricks in the negative could have a dramatic effect. The choice of the field of view can have a strong effect, effectively 'censoring out' other parts of the scene, accomplished by cropping them out or simply not including them in the photograph. This even touches on the philosophical question of what reality is. The human brain processes information based on previous experience, making us see what we want to see or what we were taught to see. Photography does the same, although the photographer interprets the scene for their viewer. === Engineering drawings === An engineering drawing is a type of drawing and is technical in nature, used to fully and clearly define requirements for engineered items. It is usually created in accordance with standardized conventions for layout, nomenclature, interpretation, appearance (such as typefaces and line styles), size, etc. === Computer graphics === There are two types of computer graphics: raster graphics, where each pixel is separately defined (as in a digital photograph), and vector graphics, where mathematical formulas are used to draw lines and shapes, which are then interpreted at the viewer's end to produce the graphic. Using vectors results in infinitely sharp graphics and often smaller files, but, when complex, like vectors take time to render and may have larger file sizes than a raster equivalent. In 1950, the first computer-driven display was attached to MIT's Whirlwind I computer to generate simple pictures. This was followed by MIT's TX-0 and TX-2, interactive computing which increased interest in computer graphics during the late 1950s. In 1962, Ivan Sutherland invented Sketchpad, an innovative program that influenced alternative forms of interaction with computers. In the mid-1960s, large computer graphics research projects were begun at MIT, General Motors, Bell Labs, and Lockheed Corporation. Douglas T. Ross of MIT developed an advanced compiler language for graphics programming. S.A.Coons, also at MIT, and J. C. Ferguson at Boeing, began work in sculptured surfaces. GM developed their DAC-1 system, and other companies, such as Douglas, Lockheed, and McDonnell, also made significant developments. In 1968, ray tracing was first described by Arthur Appel of the IBM Research Center, Yorktown Heights, N
Information Processing Language
Information Processing Language (IPL) is a programming language created by Allen Newell, Cliff Shaw, and Herbert A. Simon at RAND Corporation and the Carnegie Institute of Technology about 1956. Newell had the job of language specifier-application programmer, Shaw was the system programmer, and Simon had the job of application programmer-user. IPL included features to facilitate AI programming, specifically problem solving. such as lists, dynamic memory allocation, data types, recursion, functions as arguments, generators, and cooperative multitasking. IPL also introduced the concepts of symbol processing and list processing. Unfortunately, all of these innovations were cast in a difficult assembly-language style. Nonetheless, IPL-V (the only public version of IPL) ran on many computers through the mid 1960s. == Basics of IPL == An IPL computer has: A set of symbols. All symbols are addresses, and name cells. Unlike symbols in later languages, symbols consist of a character followed by a number, and are written H1, A29, 9–7, 9–100. Cell names beginning with a letter are regional, and are absolute addresses. Cell names beginning with "9-" are local, and are meaningful within the context of a single list. One list's 9-1 is independent of another list's 9–1. Other symbols (e.g., pure numbers) are internal. A set of cells. Lists are made from several cells including mutual references. Cells have several fields: P, a 3-bit field used for an operation code when the cell is used as an instruction, and unused when the cell is data. Q, a 3-valued field used for indirect reference when the cell is used as an instruction, and unused when the cell is data. SYMB, a symbol used as the value in the cell. A set of primitive processes, which would be termed primitive functions in modern languages. The data structure of IPL is the list, but lists are more intricate structures than in many languages. A list consists of a singly linked sequence of symbols, as might be expected—plus some description lists, which are subsidiary singly linked lists interpreted as alternating attribute names and values. IPL provides primitives to access and mutate attribute value by name. The description lists are given local names (of the form 9–1). So, a list named L1 containing the symbols S4 and S5, and described by associating value V1 to attribute A1 and V2 to A2, would be stored as follows. 0 indicates the end of a list; the cell names 100, 101, etc. are automatically generated internal symbols whose values are irrelevant. These cells can be scattered throughout memory; only L1, which uses a regional name that must be globally known, needs to reside in a specific place. IPL is an assembly language for manipulating lists. It has a few cells which are used as special-purpose registers. H1, for example, is the program counter. The SYMB field of H1 is the name of the current instruction. However, H1 is interpreted as a list; the LINK of H1 is, in modern terms, a pointer to the beginning of the call stack. For example, subroutine calls push the SYMB of H1 onto this stack. H2 is the free-list. Procedures which need to allocate memory grab cells off of H2; procedures which are finished with memory put it on H2. On entry to a function, the list of parameters is given in H0; on exit, the results should be returned in H0. Many procedures return a Boolean result indicating success or failure, which is put in H5. Ten cells, W0-W9, are reserved for public working storage. Procedures are "morally bound" (to quote the CACM article) to save and restore the values of these cells. There are eight instructions, based on the values of P: subroutine call, push/pop S to H0; push/pop the symbol in S to the list attached to S; copy value to S; conditional branch. In these instructions, S is the target. S is either the value of the SYMB field if Q=0, the symbol in the cell named by SYMB if Q=1, or the symbol in the cell named by the symbol in the cell named by SYMB if Q=2. In all cases but conditional branch, the LINK field of the cell tells which instruction to execute next. IPL has a library of some 150 basic operations. These include such operations as: Test symbols for equality Find, set, or erase an attribute of a list Locate the next symbol in a list; insert a symbol in a list; erase or copy an entire list Arithmetic operations (on symbol names) Manipulation of symbols; e.g., test if a symbol denotes an integer, or make a symbol local I/O operations "Generators", which correspond to iterators and filters in functional programming. For example, a generator may accept a list of numbers and produce the list of their squares. Generators could accept suitably designed functions—strictly, the addresses of code of suitably designed functions—as arguments. == History == IPL was first utilized to demonstrate that the theorems in Principia Mathematica which were proven laboriously by hand, by Bertrand Russell and Alfred North Whitehead, could in fact be proven by computation. According to Simon's autobiography Models of My Life, this application was originally developed first by hand simulation, using his children as the computing elements, while writing on and holding up note cards as the registers which contained the state variables of the program. IPL was used to implement several early artificial intelligence programs, also by the same authors: the Logic Theorist (1956), the General Problem Solver (1957), and their computer chess program NSS (1958). Several versions of IPL were created: IPL-I (never implemented), IPL-II (1957 for JOHNNIAC), IPL-III (existed briefly), IPL-IV, IPL-V (1958, for IBM 650, IBM 704, IBM 7090, Philco model 212, many others. Widely used). IPL-VI was a proposal for an IPL hardware. A co-processor “IPL-VC” for the CDC 3600 at Argonne National Libraries was developed which could run IPL-V commands. It was used to implement another checker-playing program. This hardware implementation did not improve running times sufficiently to “compete favorably with a language more directly oriented to the structure of present-day machines”. IPL was soon displaced by Lisp, which had much more powerful features, a simpler syntax, and the benefit of automatic garbage collection. == Legacy to computer programming == IPL arguably introduced several programming language features: List manipulation—but only lists of atoms, not general lists Property lists—but only when attached to other lists Higher-order functions—while assembly programming had always allowed computing with the addresses of functions, IPL was an early attempt to generalize this property of assembly language in a principled way Computation with symbols—though symbols have a restricted form in IPL (letter followed by number) Virtual machine Many of these features were generalized, rationalized, and incorporated into Lisp and from there into many other programming languages during the next several decades.