Foma is a free and open source finite-state toolkit created and maintained by Mans Hulden. It includes a compiler, programming language, and C library for constructing finite-state automata and transducers (FST's) for various uses, most typically Natural Language Processing uses such as morphological analysis. Foma can replace the proprietary Xerox Finite State Toolkit for compiling and running FST's written in the lexc and xfst formalisms. The speed is comparable with the Xerox tools for most lexicons, although Foma can be 3 or 4 times slower for very large lexicons (e.g. >100,000 words). Foma is also one of the possible backends of the free and open source Helsinki Finite State Toolkit (where other backends provide support for further formalisms). There are several FOSS morphologies written in lexc/xfst compatible with foma, e.g. for the Sámi, Cornish, Faroese, Finnish, Komi, Mari, Udmurt, Buriat, Greenlandic language and Iñupiaq languages.
Imaging phantom
An imaging phantom, or simply phantom (less commonly spelled fantom), is a specially designed object that is scanned or imaged in the field of medical imaging to evaluate, analyze, and tune the performance of various imaging devices. A phantom is more readily available and provides more consistent results than the use of a living subject or cadaver, while also avoiding direct risks to living subjects. Phantoms were originally employed in 2D x-ray–based imaging techniques such as radiography or fluoroscopy, but more recently phantoms with desired imaging characteristics have been developed for 3D techniques such as SPECT, MRI, CT, ultrasound, PET, and other imaging modalities. == Design == A phantom used to evaluate an imaging device should respond in a similar manner to how human tissues and organs would act in that specific imaging modality. For instance, phantoms made for 2D radiography may hold various quantities of x-ray contrast agents with similar x-ray absorbing properties (such as the attenuation coefficient) to normal tissue to tune the contrast of the imaging device or modulate the patient's exposure to radiation. In such a case, the radiography phantom would not necessarily need to have similar textures and mechanical properties since these are not relevant in x-ray imaging modalities. However, in the case of ultrasonography, a phantom with similar rheological and ultrasound scattering properties to real tissue would be essential, but x-ray absorbing properties would not be relevant. The term "phantom" describes an object that is designed to resemble human tissue and can be evaluated, analyzed or manipulated to study the performance of a medical device. Phantoms are created using a digital file that is rendered through magnetic resonance imaging (MRI) or computer-aided design (CAD). The digital files allow for quick modifications that are read by the 3D printer. The 3D printer will create the product in successive layers using polymeric materials. There are several types of phantoms including tissue-mimicking, radiological phantoms, dental phantoms, BOMABs (used to calibrate whole-body counters), and more.
KoalaPad
The KoalaPad is a graphics tablet, released in 1983 by US company Koala Technologies Corporation, for the Apple II, TRS-80 Color Computer (as the TRS-80 Touch Pad), Atari 8-bit computers, Commodore 64, and IBM PC compatibles. Originally designed by Dr. David Thornburg as a low-cost computer drawing tool for schools, the Koala Pad and the bundled drawing program, KoalaPainter, was popular with home users as well. KoalaPainter was called KoalaPaint in some versions for the Apple II, and PC Design for the IBM PC. A program called Graphics Exhibitor was included for creating slideshow presentations from KoalaPainter drawings. == Description == The pad was four inches square (i.e. roughly 10×10 cm) and mounted on a slightly inclined base with the back of the pad higher than the front. At the top, "behind" the pad, were two buttons. The pad hooked into the computer using the analog signals of the joystick ports (the so-called paddle inputs), which meant that it had a low resolution and tended to jostle the cursor if moved during use. As an alternative to the drawing stylus, the pad could as easily be operated by the user's fingers for tasks that demanded less precision, such as selecting between menu items (thus using the pad as a kind of "indirect touch screen"). The top-mounted buttons tended to be somewhat frustrating to use, as the user had to "reach around" the stylus to push the buttons in order to start or stop drawing. A similar tablet from Atari, the Atari CX77 Touch Tablet, addressed this with a built-in button on the stylus, which some enterprising users adapted for use with their KoalaPad. == KoalaPainter == The pad shipped with a simple bitmap graphics editor developed by Audio Light called KoalaPainter, PC Design or Micro Illustrator depending on the target machine (see release history). Although bundled with the pad, KoalaPainter could also be operated using an ordinary digital joystick. One unique feature of the program, for its time, was that it held two pictures in the computer's memory, allowing the user to flip from one to the other—a function commonly used in order to study the differences between an original and a modified picture, and to copy and paste between two different pictures. Some third-party bitmap editors could also be used with the KoalaPad, such as Broderbund's Dazzle Draw for the Apple II. === Release history === KoalaPainter for Commodore 64 (1983) and Atari 8-bit computers (1983) PC Design for the IBM PC (1983) Micro Illustrator for the Apple II (1983), Atari 8-bit computers (1983) and Commodore Plus/4 (1984) KoalaPainter II for Commodore 64 (1984) === Reception === Ahoy! called KoalaPainter "a very powerful and effective color drawing package", and concluded that it and the KoalaPad were "excellent in ease of use, a fine choice for a beginner as well as young children". BYTE's reviewer stated in December 1984 that he made far fewer errors when using an Apple Mouse with MousePaint than with a KoalaPad and its software. He found that MousePaint was easier to use and more efficient, predicting that the mouse would receive more software support than the pad. Cassie Stahl in InfoWorld's Essential Guide to Atari Computers praised the tablet and its documentation, rating it "Excellent" among all categories and stating that "Playing with the KoalaPad becomes addictive. It does everything it claims to, and it does it well". She also liked Micro Illustrator, rating it "Excellent" except for "Good" for Performance. While criticizing the limited erase function, Stahl reported an undocumented feature enabling exporting pictures to other software. === File format === The Commodore 64 version of KoalaPainter used a fairly simple file format corresponding directly to the way bitmapped graphics are handled on the computer: A two-byte load address, followed immediately by 8,000 bytes of raw bitmap data, 1,000 bytes of raw "Video Matrix" data, 1,000 bytes of raw "Color RAM" data, and a one-byte Background Color field. == KoalaWare == Koala Technologies offered more software beyond the bundled KoalaPainter and Graphics Exhibitor for use with the pad. Among these applications, marketed under the moniker KoalaWare (like KoalaPainter itself), was educational software for use with customized keypads and overlays, such as spelling tools, music programs, and mathematics instruction software, as well as software for "translating" graphical designs into Logo programs.
Auto-defrost
Auto-defrost, automatic defrost or self-defrosting is a technique which regularly defrosts the evaporator in a refrigerator or freezer. Appliances using this technique are often called frost free, frostless, or no-frost. == Mechanism == The defrost mechanism in a refrigerator heats the cooling element (evaporator coil) for a short period of time and melts the frost that has formed on it. The resulting water drains through a duct at the back of the unit. Defrosting is controlled by an electric or electronic timer. For every 6, 8, 10, 12 or 24 hours of compressor operation, it turns on a defrost heater for 15 minutes to half an hour. The defrost heater, having a typical power rating of 350W to 600W, is often mounted just below the evaporator in top and bottom-freezer models. It can also be located below and in the middle of the evaporator in side-by-side models. It may be protected from short circuits by means of fusible links. In older refrigerators, the timer runs continuously. In newer designs, the timer only runs while the compressor runs, so the longer the refrigerator door is closed, the less time the heater will run for and the more energy is saved. A defrost thermostat opens the heater circuit when the evaporator temperature rises above a preset temperature, 40°F (5°C) or more, thereby preventing excessive heating of the freezer compartment. The defrost timer is such that either the compressor or the defrost heater is on, but not both at the same time. Inside the freezer, air is circulated by means of one or more fans. In a typical design cold air from the freezer compartment is ducted to the fresh food compartment and circulated back into the freezer compartment. Air circulation helps sublimate any ice or frost that may form on frozen items in the freezer compartment. While defrosting, this fan is stopped to prevent heated-up air from reaching the food compartment. Instead of the normal cooling elements being embedded in the freezer liner, auto-defrost elements are behind or beneath the liner. This allows them to be heated for short periods of time to dispose of frost, without heating the contents of the freezer. Alternatively, some systems use the hot gas in the condenser to defrost the evaporator. This is done by means of a circuit that is cross-linked by a three-way valve. The hot gas quickly heats up the evaporator and defrosts it. This system is primarily used in commercial applications such as ice-cream displays. == Application == While this technique was originally applied to the refrigerator compartment, it was later used for freezer compartment as well. A combined refrigerator/freezer which applies self-defrosting to the refrigerator compartment only is usually called "partial frost free" or semi-automatic defrost (some brands call these "Auto Defrost" while Frigidaire referred to their semi-automatic models as "Cycla-Matic," Kelvinator often named these models as "Cyclic Defrost" ). These refrigerators usually have a pan underneath where water from the melted frost in the refrigerator section evaporates. Freezers with automatic defrosting and combined refrigerator/freezer units which also apply self defrosting to their freezer compartment are called "frost free". The latter usually feature an air connection between the two compartments with the air passage to the refrigerator compartment regulated by a damper. By this means, a controlled portion of the air coming from the freezer reaches the refrigerator. Some older models have no air circulation between their freezer and refrigerator sections. Instead, they use an independent cooling system (for example: an evaporator coil with a defrost heater and a circulating fan in the freezer and a cold-plate or open-coil evaporator in the refrigerator. "Frost-Free" refrigerator/freezer units usually use a heating element to defrost their evaporators, a pan to collect and evaporate water from the frost that melts from the cold plate and/or evaporator coil, a timer which turns off the compressor and turns on the defrost element usually from once to 4 times a day for periods usually ranging from 15 to 30 minutes, a defrost limiter thermostat that turns off the heating element before the temperature rises too much while the timer is still in its defrost phase. Some models also feature a drain heater to prevent ice from blocking the drain. Other early types of refrigerators also use hot gas defrost instead of electric heaters. These reverse the evaporator and condenser sides for the defrost cycle. Some newer refrigerator/freezer models have a computer that monitors how many times each door is opened and uses this data to control defrost scheduling thereby reducing power use. == Advantages == No need to manually defrost the frost buildup, therefore power consumption will not increase with time. Food packaging is easier to see. Most frozen food will not stick together. Smells are limited, especially in total frost-free appliances because the air always circulates. Better temperature management. == Disadvantages == The system can be more expensive to run when usage is high and if the fan continues or starts to run when the door is opened. A thermal cutout safety device is required to prevent overheating of the heating element. Increased electrical and mechanical complexity compared to a basic upright freezer or chest freezer, making it more prone to component failure. The temperature of the freezer contents rises during the defrosting cycles, especially if there is a light load in the freezer. This can cause "freezer burn" on articles placed in the freezer, from partially defrosting, then re-freezing On hot, humid days condensation will sometimes form around the refrigerator doors. Defrosting may not be completed by the time the defrost timer cycles back to normal operation (especially in hot, humid conditions with frequent door openings), leaving ice/frost on the evaporator coils. This condition can lead to "icing" which will interfere with the operation of the refrigerator. In laboratories, self-defrosting freezers must not be used to store certain delicate reagents such as enzymes, because the temperature cycling can degrade them. In addition, water can evaporate out of containers that do not have a very tight seal, altering the concentration of the reagents. Self-defrosting freezers should never be used to store flammable chemicals.
Image translation
Image translation is the machine translation of images of printed text (posters, banners, menus, screenshots etc.). This is done by applying optical character recognition (OCR) technology to an image to extract any text contained in the image, and then have this text translated into a language of their choice, and the applying digital image processing on the original image to get the translated image with a new language. == General == Machine translation made available on the internet (web and mobile) is a notable advance in multilingual communication eliminating the need for an intermediary translator/interpreter, translating foreign texts still poses a problem to the user as they cannot be expected to be able to type the foreign text they wish to translate and understand. Manually entering the foreign text may prove to be a difficulty especially in cases where an unfamiliar alphabet is used from a script which user can't read, e.g. Cyrillic, Chinese, Japanese etc. for an English speaker or any speaker of a Latin-based language or vice versa. The technical advancements in OCR made it possible to recognize text from images. The possibility to use one's mobile device's camera to capture and extract printed text is also known as mobile OCR and was first introduced in Japanese manufactured mobile telephones in 2004. Using the handheld's camera one could take a picture of (a line of) text and have it extracted (digitalized) for further manipulation such as storing the information in their contacts list, as a web page address (URL) or text to use in an SMS/email message etc. Presently, mobile devices having a camera resolution of 2 megapixels or above with an auto-focus ability, often feature the text scanner service. Taking the text scanning facility one step further, image translation emerged, giving users the ability to capture text with their mobile phone's camera, extract the text, and have it translated in their own language. More and more applications emerged on this technology including Word Lens. After getting acquired by Google, it was made a part of Google Translate mobile app. Another simultaneous advancement in Image Processing, has also made it possible now to replace the text on the image with the translated text and create a new image altogether. == History == The development of the image translation service springs from the advances in OCR technology (miniaturization and reduction of memory resources consumed) enabling text scanning on mobile telephones. Among the first to announce mobile software capable of “reading” text using the mobile device's camera is International Wireless Inc. who in February 2003 released their “CheckPoint” and “WebPoint” applications. “CheckPoint” reads critical symbolic information on checks and is aimed at reducing losses that mobile merchants suffer from “bounced” checks by scanning the MICR number on the bottom of a check, while “WebPoint” enables the visual recognition and decoding of printed URL's, which are then opened by the device's web browser. The first commercial release of a mobile text scanner, however, took place in December 2004 when Vodafone and Sharp began selling the 902SH mobile which was the first to feature a 2 megapixel digital camera with optical zoom. Among the device's various multimedia features was the built-in text/bar code/QR code scanner. The text scanner function could handle up to 60 alphabetical characters simultaneously. The scanned text could be then sent as an email or SMS message, added as a dictionary entry or, in the case of scanned URLs, opened via the device's web browser. All subsequent Sharp mobiles feature the text scanner functionality. In September 2005, NEC Corporation and the Nara Institute of Science and Technology in Japan (NAIST) announced new software capable of transforming cameraphones into text scanners. The application differs substantially from similarly equipped mobile telephones in Japan (able to scan businesscards and small bits of text and use OCR to convert that to editable text or to URL addresses) by it ability to scan a whole page. The two companies, however, said they would not release the software commercially before the end of 2008. Combining the text scanner function with machine translation technology was first made by US company RantNetwork who in July 2007 started selling the Communilator, a machine translation application for mobile devices featuring the Image Translation functionality. Using the built-in camera, the mobile user could take a picture of some printed text, apply OCR to recognize the text and then translate it into any one of over 25 language available. In April 2008 Nokia showcased their Shoot-to-Translate application for the N73 model which is capable of taking a picture using the device's camera, extracting the text and then translating it. The application only offers Chinese to English translation, and does not handle large segments of text. Nokia said they are in the process of developing their Multiscanner product which, besides scanning text and business cards, would be able to translate between 52 languages. Again in April 2008, Korean company Unichal Inc. released their handheld Dixau text scanner capable of scanning and recognizing English text and then translating it into Korean using online translation tools such as Wikipedia or Google Translate. The device is connected to a PC or a laptop via the USB port. In February 2009, Bulgarian company Interlecta presented at the Mobile World Congress in Barcelona their mobile translator including image recognition and speech synthesis. The application handles all European languages along with Chinese, Japanese and Korean. The software connects to a server over the Internet to accomplish the image recognition and the translation. In May 2014, Google acquired Word Lens to improve the quality of visual and voice translation. It is able to scan text or picture with one's device and have it translated instantly. Since the OCR has been improving many companies or website started combining OCR and translation, to read the text from an image and show the translated text. In August 2018, an Indian company created ImageTranslate. It is able to read, translate and re-create the image in another language. As of late 2018, the tool added 13 new languages, including Arabic, Thai, Vietnamese, Hindi, and Bengali, significantly increasing its utility in Asia and the Middle East. This helps users translate photos already stored in their phone's gallery, not just live, real-time views. Currently, image translation is offered by the following companies: Google Translate app with camera ImageTranslate Yandex
Threat actor
In cybersecurity and risk assessment, a threat actor (or threat agents, attackers, or adversaries) is a person, group, organisation, state, or other entity with the ability to cause, carry, transmit, support, or exploit a threat. Threat actors are commonly analysed according to their motivations, resources, technical capability, access to systems, relationship to a target, and degree of connection to state authority. They may exploit vulnerabilities, conduct social engineering, steal or monetise data, disrupt operations, or support other actors who carry out such activity. Because the term covers a wide range of actors, researchers and security organisations use taxonomies that distinguish between groups such as cybercriminals, state-linked actors, ideologically motivated actors, thrill seekers or trolls, insiders, and competitors. Threat actor classifications are used in risk management, cyber threat intelligence, and incident response to connect observed behaviour with possible objectives and likely future activity. The categories are not always mutually exclusive: the same actor may combine criminal, ideological, commercial, or state-linked motivations, and different organisations may use different names for similar actors. == Risk assessment and security management == In risk assessment, threat actor analysis is used to identify who or what may create, carry, transmit, support, or exploit a threat, and how that actor relates to the system being assessed. Rausand and Haugen classify threat actors by their relationship to the system, distinguishing between internal and external actors, and by intent, distinguishing between intentional and unintentional actors. Threat actor classification may also support incident investigation. Rogers argued that actor categories could be inferred from observable case points, such as tools used, messages left, data targeted, forensic knowledge, and the degree of damage, allowing investigators to assess likely motivation and skill level. Later work similarly linked actor classification to operational analysis. Chng, Lu, Kumar and Yau proposed a framework connecting hacker types, motivations and typical strategies, arguing that observed behaviour before or during an attack can help analysts infer the likely type of actor involved. At the strategic level, actor analysis may consider an actor's resources, capabilities, degree of state involvement, motivations and objectives. == Landscape == The United Nations Institute for Disarmament Research has described the contemporary cyberthreat landscape as involving an increasingly diverse and interconnected set of actors, including state-led operations, cybercriminal syndicates, ideological hacktivists, commercial cyber mercenaries, private companies and civilian volunteers. Its 2026 report argued that these actors vary in resources, technical sophistication and relationships with states, making it traditional distinctions between state, civilian combatant roles, and legitimate and illegitimate conduct harder to apply. == Academic taxonomies == Early taxonomies classified hackers by activity, skill, motivation, or criminal profile. Landreth proposed six categories based on activity: novice, student, tourist, crasher, and thief. Hollinger classified computer misuse into pirates, browsers, and crackers, describing a progression from less-skilled activity to more technically serious offences. Chantler used attributes including activity, skill, knowledge, motivation, and duration of involvement to distinguish between an elite group, neophytes, and "losers and lamers". Parker proposed seven profiles of cybercriminals: pranksters, hacksters, malicious hackers, personal problem solvers, career criminals, extreme advocates, and malcontents, addicts, and irrational or incompetent people. In 2000, Marc Rogers proposed a taxonomy of hackers with seven, non-mutually-exclusive categories: newbie/tool kit users, cyber-punks, internals, coders, old guard hackers, professional criminals, and cyber-terrorists. Rausand and Haugen distinguish between internal and external threat actors, and between intentional and unintentional threat actors. Internal actors have some relationship with, access to, or position inside the system or organisation, while external actors operate from outside it. Intentional actors seek to create, exploit, or support a threat event, whereas unintentional actors may cause or enable a threat event through error, negligence, accident, or lack of awareness. Rogers later revised his hacker taxonomy into Novices, Cyber-punks, Internals, Petty Thieves, Virus Writers, Old Guard hackers, Professional Criminals, Information Warriors, and, more tentatively, Political Activists. In the model, motivation is grouped into four broad domains: curiosity, notoriety, revenge, and financial gain. A 2022 review by Chng, Lu, Kumar and Yau examined 11 hacker typologies published over three decades and proposed a unified framework linking hacker types, motivations, and strategies. The framework identified 13 hacker types and seven motivations, and argued that observed strategies during an attack can help analysts infer the likely type of actor involved. == Government taxonomies == Taxonomies of threat actors by governments are much more likely to include state-level threat actors. In the United States the National Institute of Standards and Technology (NIST) uses the term threat source in its risk-assessment guidance: organisations are directed to identify and characterise threat sources of concern, including capability, intent and targeting for adversarial threat sources, and the range of effects for non-adversarial threat sources. NIST treats threat-source identification as part of the risk-assessment process, alongside identifying threat events, vulnerabilities, likelihood and impact. In the EU, European Union Agency for Cybersecurity publishes the annual ENISA Threat Landscape, which analyses cyber incidents and adversary behaviour affecting the European Union. The 2025 report analysed selected incidents from the previous year and grouped activity around cybercrime, state-aligned activity, foreign information manipulation and interference, and hacktivism. In ENISA's 2025 analysis, hacktivist activity dominated reporting, representing almost 80% of recorded incidents and consisting mainly of low-level distributed denial-of-service operations. ENISA also reported increasing convergence between hacktivism, cybercrime and state-nexus activity, including state-aligned use of hacktivist personas, hacktivist adoption of ransomware, and false-flag or impersonation activity. At the UN level, A 2026 report by the United Nations Institute for Disarmament Research described the cyberthreat landscape as involving state-led operations, cybercriminal syndicates, ideological hacktivists, commercial cyber mercenaries, and civilian volunteers, with actors varying in resources, technical sophistication, and links to states. Canada defines threat actors as states, groups, or individuals who aim to cause harm by exploiting a vulnerability with malicious intent. A threat actor must be trying to gain access to information systems to access or alter data, devices, systems, or networks. The Japanese government's National Centre of Incident Readiness and Strategy (NISC) was established in 2015 to create a "free, fair and secure cyberspace" in Japan. The NICS created a cybersecurity strategy in 2018 that outlines nation-states and cybercrime to be some of the most key threats. It also indicates that terrorist usage of the cyberspace needs to be monitored and understood. The Security Council of the Russian Federation published the cyber security strategy doctrine in 2016. This strategy highlights the following threat actors as a risk to cyber security measures: nation-state actors, cyber criminals, and terrorists. == Techniques == Threat actors use techniques like Social engineering (security), and Phishing, alongside technical exploits like Cross-site scripting, SQL injection, and denial-of-service attacks. == Limitations == In practice, actor categories may overlap (Edward Snowden for example), and the same activity may combine features associated with hacktivism, cybercrime and state-linked operations. The lines between hacktivism, cybercrime and state-nexus activity had continued to blur, with shared toolsets, overlapping methods, fake personas, hacktivist adoption of ransomware, and cybercriminal or state-linked actors masquerading as other groups. Threat actor analysis also has limits as a risk-management method. NIST notes that risk assessments depend on their purpose, scope, assumptions, constraints, information sources, risk model and analytic approach, and that assessments are tied to particular time frames and organisational contexts. NIST also warns that simple threat-vulnerability pairing may be undesirable or problematic where there are many threats and vulnerabilities, and recom
Biorobotics
Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems. == Cybernetics == Cybernetics focuses on the communication and system of living organisms and machines that can be applied and combined with multiple fields of study such as biology, mathematics, computer science, engineering, and much more. This discipline falls under the branch of biorobotics because of its combined field of study between biological bodies and mechanical systems. Studying these two systems allows for advanced analysis on the functions and processes of each system as well as the interactions between them. === History === Cybernetic theory is a concept that has existed for centuries, dating back to the era of Plato where he applied the term to refer to the "governance of people". The term cybernetique is seen in the mid-1800s used by physicist André-Marie Ampère. The term cybernetics was popularized in the late 1940s to refer to a discipline that touched on, but was separate, from established disciplines, such as electrical engineering, mathematics, and biology. === Science === Cybernetics is often misunderstood because of the breadth of disciplines it covers. In the early 20th century, it was coined as an interdisciplinary field of study that combines biology, science, network theory, and engineering. Today, it covers all scientific fields with system related processes. The goal of cybernetics is to analyze systems and processes of any system or systems in an attempt to make them more efficient and effective. === Applications === Cybernetics is used as an umbrella term so applications extend to all systems related scientific fields such as biology, mathematics, computer science, engineering, management, psychology, sociology, art, and more. Cybernetics is used amongst several fields to discover principles of systems, adaptation of organisms, information analysis and much more. == Genetic engineering == Genetic engineering is a field that uses advances in technology to modify biological organisms. Through different methods, scientists are able to alter the genetic material of microorganisms, plants and animals to provide them with desirable traits. For example, making plants grow bigger, better, and faster. Genetic engineering is included in biorobotics because it uses new technologies to alter biology and change an organism's DNA for their and society's benefit. === History === Although humans have modified genetic material of animals and plants through artificial selection for millennia (such as the genetic mutations that developed teosinte into corn and wolves into dogs), genetic engineering refers to the deliberate alteration or insertion of specific genes to an organism's DNA. The first successful case of genetic engineering occurred in 1973 when Herbert Boyer and Stanley Cohen were able to transfer a gene with antibiotic resistance to a bacterium. === Science === There are three main techniques used in genetic engineering: The plasmid method, the vector method and the biolistic method. ==== Plasmid method ==== This technique is used mainly for microorganisms such as bacteria. Through this method, DNA molecules called plasmids are extracted from bacteria and placed in a lab where restriction enzymes break them down. As the enzymes do this, some develop a rough edge that resembles that of a staircase which is considered 'sticky' and capable of reconnecting. These 'sticky' molecules are inserted into another bacteria where they will connect to the DNA rings with the altered genetic material. ==== Vector method ==== The vector method is considered a more precise technique than the plasmid method as it involves the transfer of a specific gene instead of a whole sequence. In the vector method, a specific gene from a DNA strand is isolated through restriction enzymes in a laboratory and is inserted into a vector. Once the vector accepts the genetic code, it is inserted into the host cell where the DNA will be transferred. ==== Biolistic method ==== The biolistic method is typically used to alter the genetic material of plants. This method embeds the desired DNA with a metallic particle such as gold or tungsten in a high speed gun. The particle is then bombarded into the plant. Due to the high velocities and the vacuum generated during bombardment, the particle is able to penetrate the cell wall and inserts the new DNA into the cell. === Applications === Genetic engineering has many uses in the fields of medicine, research and agriculture. In the medical field, genetically modified bacteria are used to produce drugs such as insulin, human growth hormones and vaccines. In research, scientists genetically modify organisms to observe physical and behavioral changes to understand the function of specific genes. In agriculture, genetic engineering is extremely important as it is used by farmers to grow crops that are resistant to herbicides and to insects such as BTCorn. == Bionics == Bionics is a medical engineering field and a branch of biorobotics consisting of electrical and mechanical systems that imitate biological systems, such as prosthetics and hearing aids. It's a portmanteau that combines biology and electronics. === History === The history of bionics goes as far back in time as ancient Egypt. A prosthetic toe made out of wood and leather was found on the foot of a mummy. The time period of the mummy corpse was estimated to be from around the fifteenth century B.C. Bionics can also be witnessed in ancient Greece and Rome. Prosthetic legs and arms were made for amputee soldiers. In the early 16th century, a French military surgeon by the name of Ambroise Pare became a pioneer in the field of bionics. He was known for making various types of upper and lower prosthetics. One of his most famous prosthetics, Le Petit Lorrain, was a mechanical hand operated by catches and springs. During the early 19th century, Alessandro Volta further progressed bionics. He set the foundation for the creation of hearing aids with his experiments. He found that electrical stimulation could restore hearing by inserting an electrical implant to the saccular nerve of a patient's ear. In 1945, the National Academy of Sciences created the Artificial Limb Program, which focused on improving prosthetics since there were a large number of World War II amputee soldiers. Since this creation, prosthetic materials, computer design methods, and surgical procedures have improved, creating modern-day bionics. === Science === ==== Prosthetics ==== The important components that make up modern-day prosthetics are the pylon, the socket, and the suspension system. The pylon is the internal frame of the prosthetic that is made up of metal rods or carbon-fiber composites. The socket is the part of the prosthetic that connects the prosthetic to the person's missing limb. The socket consists of a soft liner that makes the fit comfortable, but also snug enough to stay on the limb. The suspension system is important in keeping the prosthetic on the limb. The suspension system is usually a harness system made up of straps, belts or sleeves that are used to keep the limb attached. The operation of a prosthetic could be designed in various ways. The prosthetic could be body-powered, externally-powered, or myoelectrically powered. Body-powered prosthetics consist of cables attached to a strap or harness, which is placed on the person's functional shoulder, allowing the person to manipulate and control the prosthetic as he or she deems fit. Externally-powered prosthetics consist of motors to power the prosthetic and buttons and switches to control the prosthetic. Myoelectrically powered prosthetics are new, advanced forms of prosthetics where electrodes are placed on the muscles above the limb. The electrodes will detect the muscle contractions and send electrical signals to the prosthetic to move the prosthetic. The downside to this type of prosthetic is that if the sensors are not placed correctly on the limb then the electrical impulses will fail to move the prosthetic. TrueLimb is a specific brand of prosthetics that uses myoelectrical sensors which enable a person to have control of their bionic limb. ==== Hearing aids ==== Four major components make up the hearing aid: the microphone, the amplifier, the receiver, and the battery. The microphone takes in outside sound, turns that sound to electrical signals, and sends those signals to the amplifier. The amplifier increases the sound and sends that sound to the receiver. The receiver changes the electrical signal back into sound and sends the sound into the ear. Hair cells in the ear will sense the vibrations from the sound, convert the vibrations into nerve signals, and send it to the brain so