Deep Tomographic Reconstruction is a set of methods for using deep learning methods to perform tomographic reconstruction of medical and industrial images. It uses artificial intelligence and machine learning, especially deep artificial neural networks or deep learning, to overcome challenges such as measurement noise, data sparsity, image artifacts, and computational inefficiency. This approach has been applied across various imaging modalities, including CT, MRI, PET, SPECT, ultrasound, and optical imaging == Historical background == Traditional tomographic reconstruction relies on analytic methods such as filtered back-projection, or iterative methods which incrementally compute inverse transformations from measurement data (e.g., Radon or Fourier transform data). However, these approaches are not sufficient for certain imaging techniques such as low-dose CT and fast MRI, or scenarios involving metal artifacts and patient motion. == Use in imaging modalities == === Computed tomography (CT) === In CT, deep learning models can be particularly effective in reducing radiation exposure while maintaining image quality. Deep neural networks can also be able to reconstruct images of fair quality from sparsely sampled data without sacrificing diagnostic performance. Deep learning-based generative AI models can reduce CT metal artifacts. === Magnetic resonance imaging (MRI) === In magnetic resonance imaging (MRI), deep learning can lead to reduced MRI motion artifacts, and increased acquisition speed, referred to as fast MRI. Despite suffering from disadvantages such as lower signal-to-noise ratio (SNR), deep learning can enhance image quality in low field MRI, making these systems clinically viable. === Positron emission tomography (PET) and single-photon emission CT (SPECT) === For PET imaging, deep learning models can provide substantial improvements in low-dose imaging and motion artifact correction. Also, deep learning can help SPECT for generation of attenuation background. A notable technique for PET denoising involves integrating MR data through multimodal networks, which use anatomical information from MRI to enhance PET image quality. === Ultrasound imaging === Deep learning can enhance ultrasound imaging by reducing speckle noise and motion blur. For ultrasound beamforming, deep neural networks can allow superior image quality with limited data at high speed. === Optical imaging and microscopy === Diffuse optical tomography, optical coherence tomography and microscopy can be improved by deep neural networks beyond traditional methods. Furthermore, deep learning can also enhance Photoacoustic imaging (see Deep learning in photoacoustic imaging), addressing challenges like high noise, low contrast, and limited resolution. Deep learning has also been applied to label-free live-cell imaging, where convolutional neural networks predict fluorescence labels from transmitted light images, a technique known as in silico labeling. This method can enable high-throughput, non-invasive cell analysis and phenotyping without the need for traditional fluorescent dyes.
Algorithmic probability
In algorithmic information theory, algorithmic probability, also known as Solomonoff probability, is a mathematical method of assigning a prior probability to a given observation. It was invented by Ray Solomonoff in the 1960s. It is used in inductive inference theory and analyses of algorithms. In his general theory of inductive inference, Solomonoff uses the method together with Bayes' rule to obtain probabilities of prediction for an algorithm's future outputs. In the mathematical formalism used, the observations have the form of finite binary strings viewed as outputs of Turing machines, and the universal prior is a probability distribution over the set of finite binary strings calculated from a probability distribution over programs (that is, inputs to a universal Turing machine). The prior is universal in the Turing-computability sense, i.e. no string has zero probability. It is not computable, but it can be approximated. Formally, the probability P {\displaystyle P} is not a probability and it is not computable. It is only "lower semi-computable" and a "semi-measure". By "semi-measure", it means that 0 ≤ ∑ x P ( x ) < 1 {\displaystyle 0\leq \sum _{x}P(x)<1} . That is, the "probability" does not actually sum up to one, unlike actual probabilities. This is because some inputs to the Turing machine causes it to never halt, which means the probability mass allocated to those inputs is lost. By "lower semi-computable", it means there is a Turing machine that, given an input string x {\displaystyle x} , can print out a sequence y 1 < y 2 < ⋯ {\displaystyle y_{1} In computer science, a single address space operating system (or SASOS) is an operating system that provides only one globally shared address space for all processes. In a single address space operating system, numerically identical (virtual memory) logical addresses in different processes all refer to exactly the same byte of data. In a traditional OS with private per-process address space, memory protection is based on address space boundaries ("address space isolation"). Single address-space operating systems make translation and protection orthogonal, which in no way weakens protection. The core advantage is that pointers (i.e. memory references) have global validity, meaning their meaning is independent of the process using it. This allows sharing pointer-connected data structures across processes, and making them persistent, i.e. storing them on backup store. Some processor architectures have direct support for protection independent of translation. On such architectures, a SASOS may be able to perform context switches faster than a traditional OS. Such architectures include Itanium, and Version 5 of the Arm architecture, as well as capability architectures such as CHERI. A SASOS should not be confused with a flat memory model, which provides no address translation and generally no memory protection. In contrast, a SASOS makes protection orthogonal to translation: it may be possible to name a data item (i.e. know its virtual address) while not being able to access it. SASOS projects using hardware-based protection include the following: Angel IBM i (formerly called OS/400) Iguana at NICTA, Australia Mungi at NICTA, Australia Nemesis Opal Scout Sombrero Related are OSes that provide protection through language-level type safety: Br1X Genera JX a research Java OS Phantom OS Singularity Theseus OS Torsion Digital anthropology is the anthropological study of the relationship between humans and digital-era technology. The field is new, and thus has a variety of names with a variety of emphases. These include techno-anthropology, digital ethnography, cyberanthropology, and virtual anthropology. == Definition and scope == Most anthropologists who use the phrase "digital anthropology" are specifically referring to online and Internet technology. The study of humans' relationship to a broader range of technology may fall under other subfields of anthropological study, such as cyborg anthropology. The Digital Anthropology Group (DANG) is classified as an interest group in the American Anthropological Association. DANG's mission includes promoting the use of digital technology as a tool of anthropological research, encouraging anthropologists to share research using digital platforms, and outlining ways for anthropologists to study digital communities. Cyberspace or the "virtual world" itself can serve as a "field" site for anthropologists, allowing the observation, analysis, and interpretation of the sociocultural phenomena springing up and taking place in any interactive space. National and transnational communities, enabled by digital technology, establish a set of social norms, practices, traditions, storied history and associated collective memory, migration periods, internal and external conflicts, potentially subconscious language features and memetic dialects comparable to those of traditional, geographically confined communities. This includes the various communities built around free and open-source software, online platforms such as Facebook, Twitter/X, Instagram, 4chan and Reddit and their respective sub-sites, and politically motivated groups like Anonymous, WikiLeaks, or the Occupy movement. A number of academic anthropologists have conducted traditional ethnographies of virtual worlds, such as Bonnie Nardi's study of World of Warcraft or Tom Boellstorff's study of Second Life. Academic Gabriella Coleman has done ethnographic work on the Debian software community and the Anonymous hacktivist network. Theorist Nancy Mauro-Flude conducts ethnographic field work on computing arts and computer subcultures such as systerserver.net a part of the communities of feminist web servers and the Feminist Internet network. Eitan Y. Wilf examines the intersection of artists' creativity and digital technology and artificial intelligence. Yongming Zhou studied how in China the internet is used to participate in politics. Eve M. Zucker and colleagues study the shift to digital memorialization of mass atrocities and the emergent role of artificial intelligence in these processes. Victoria Bernal conducted ethnographic research on the themes of nationalism and citizenship among Eritreans participating in online political engagement with their homeland. Anthropological research can help designers adapt and improve technology. Australian anthropologist Genevieve Bell did extensive user experience research at Intel that informed the company's approach to its technology, users, and market. == Methodology == === Digital fieldwork === Many digital anthropologists who study online communities use traditional methods of anthropological research. They participate in online communities in order to learn about their customs and worldviews, and back their observations with private interviews, historical research, and quantitative data. Their product is an ethnography, a qualitative description of their experience and analyses. Other anthropologists and social scientists have conducted research that emphasizes data gathered by websites and servers. However, academics often have trouble accessing user data on the same scale as social media corporations like Facebook and data mining companies like Acxiom. In terms of method, there is a disagreement in whether it is possible to conduct research exclusively online or if research will only be complete when the subjects are studied holistically, both online and offline. Tom Boellstorff, who conducted a three-year research as an avatar in the virtual world Second Life, defends the first approach, stating that it is not just possible, but necessary to engage with subjects “in their own terms”. Others, such as Daniel Miller, have argued that an ethnographic research should not exclude learning about the subject's life outside the internet. === Digital technology as a tool of anthropology === The American Anthropological Association offers an online guide for students using digital technology to store and share data. Data can be uploaded to digital databases to be stored, shared, and interpreted. Text and numerical analysis software can help produce metadata, while a codebook may help organize data. == Ethics == Online fieldwork offers new ethical challenges. According to the American Anthropological Association's ethics guidelines, anthropologists researching a community must make sure that all members of that community know they are being studied and have access to data the anthropologist produces. However, many online communities' interactions are publicly available for anyone to read, and may be preserved online for years. Digital anthropologists debate the extent to which lurking in online communities and sifting through public archives is ethical. The Association also asserts that anthropologists' ability to collect and store data at all is "a privilege", and researchers have an ethical duty to store digital data responsibly. This means protecting the identity of participants, sharing data with other anthropologists, and making backup copies of all data. == Prominent figures == Genevieve Bell is an Australian cultural anthropologist credited for pioneering the User Experience field. During her time working for Intel Corporation, Bell studied how various cultures from around the world interacted with and experienced technology. Researching and improving user experience allows companies and designers to gather data regarding how users utilize their digital products and what requires improvement or expansion. Tom Boellstorff is an anthropologist known for Coming of Age in Second Life: An Anthropologist Explores the Virtually Human where he conducted research on how engaging in virtual worlds affects the player’s sense of self. Gabriella Coleman is an American anthropologist concerned with the politics, ethics, and culture of hacking and online activism. Coleman’s most notable ethnography features the hacktivist collective Anonymous, where she argues that various genres of hacking exist according to the social conditions at play. Coleman is dedicated to making her ethnography accessible to a diverse audience, including academics and non-academics. Diana E. Forsythe was an American anthropologist of science and technology and the author of the essays featured in Studying Those Who Study Us: An Anthropologist in the World of Artificial Intelligence. She asked relevant questions such as how should humans interact with computers and how gender roles are maintained in technology-oriented occupations. Heather Horst is a sociocultural anthropologist interested in the relationship between digital social relations and material culture. Nancy Mauro-Flude is a design anthropologist whose work explores the tacit relations between embodied cognition, computational materiality, maker culture, self-hosted webserver cooperatives, creative practice, and artistic research in digital infrastructure and Internet publishing. Mizuko Ito is a Japanese cultural anthropologist specializing in technology use and the intersection between computers and the social sciences. Her primary interest is in how young people utilize media technology and how it can be used to engage students in education. Daniel Miller is an anthropologist with a concentration in digital anthropology. His research includes the smartphone and perpetual opportunism, the intent and consequences of posting on social media in various geographical locations, and how hospice patients use media to socialize in the last stage of their lives. Mike Wesch is a cultural anthropologist interested in how people share their lives, cultures, and beliefs through digital media. KKday is an online travel e-commerce platform focused on connecting independent travelers with authentic, curated local experiences, tours, activities, and attraction tickets. == History == KKday was founded in 2014 in Taipei, Taiwan, by CEO Ming Chen, who previously started and led both Star Travel and Ezfly to IPO. In March of 2016, the company raised US$4.5 million in a Series A round led by AppWorks Ventures with participation by 91Capital. The raise allowed KKday to open offices and expand into Hong Kong, Japan, South Korea and Singapore by 2016. By the end of 2016, KKday offered over 6,000 travel experiences across 53 countries and 174 cities, marking early international expansion with its official launch in Singapore in October 2016, accompanied by promotional campaigns to attract regional users. Expansion into Malaysia, Thailand, Vietnam and the Philippines continued throughout 2017 and into 2018, with the company opening offices in Indonesia and mainland China. KKday rapidly expanded its inventory, reaching over 10,000 experiences in more than 500 cities across 80 countries by 2018, with key markets in Taiwan, Hong Kong, and South Korea. In February 2018, KKday raised $10.5 million in a funding round led by Japanese travel giant H.I.S., allowing integration with larger travel networks and further global growth. Forbes reports that by the end of 2018, the company operated in 11 countries and regions, employed around 400 staff, and recorded over 4 million weekly website views with more than 1 million app downloads. A combination of a Japanese and South Korean trade dispute, along with the Covid-19 pandemic in 2020, lead KKday to pivot quickly toward domestic staycations and local experiences while initially raising $70m in their Series C which, was later extended to $95m. The Series C funds were partially used to accelerate and expand Rezio. Launched in 2019, Rezio is KKday's B2B SaaS booking management platform for travel providers, allowing them to track inventory, manage reservations and sell tickets. FineDayClub was launched in 2020 by KKday as a personalized luxury subscription travel service to cater to high end clients. KKday’s CFO, Jenny Tsai pivoted to lead KKday’s new venture. KKday was able to successfully navigate and adapt to travel patterns during the Covid-19 pandemic by reducing user acquisition costs by two thirds and focusing on domestic travel experiences to drive bookings and revenue. KKday was particularly successful in Vietnam, with bookings increased by 2,000% through 2022 and the company's travel operator platform Rezio, onboarding over 1,200 operators inside the country. In 2021, KKday acquired Activity Japan, a domestic focused travel company, founded by Kimiharu Obuchi in 2014. The successful acquisition, a key factor in KKday’s rapid expansion in the Japanese market, was facilitated by H.I.S., a common early investor in both platforms. In 2023 KKday inked a partnership with Rail Europe to create an all-in-one platform for 150 rail lines over 33 European countries with the intent of increasing ridership across Europe. In late 2024, KKday completed its Series D at $70M, bringing the total amount of capital raised to over $250M. The funds are to be earmarked for continued global expansion, artificial intelligence integration and enhanced partnerships, similar to the partnership with Tablelog, which now allows users to book restaurant reservations at 42,000 restaurants in Japan through the platform. == Platform == KKDay is an e-commerce online travel agency operating in 92 countries with over 350,000 travel experiences available for booking. The company started with focus on authentic local travel experiences in the Asian Pacific market and has expanded to a more global focus. KKday connects travelers with travel services and experiences such as attraction tickets, theme parks, cultural experiences, and seasonal events. KKday has positioned itself as an all-in-one travel super app with booking for hotels, rental cars, flights, sim cards, rail passes, dining and tickets. === Rezio === Rezio is a cloud-based SaaS booking management platform developed by KKday specifically for tour operators, activity providers, and attractions in the travel industry. It serves as an all-in-one system designed to help these businesses digitize their operations, particularly those previously relying on offline processes. Features include a mobile app for on-the-go order management, customer information checks, and voucher scanning, as well as channel management, analytics for customer data, and integrations with multiple OTAs and payment providers. Unlike KKday, which is an OTA marketplace for consumer exposure (with commissions), Rezio focuses on backend operations for suppliers, allowing brand independence, operational efficiency, and direct customer relationships while optionally connecting to OTAs like KKday. Rezio supports over 5,000 merchants, 30,000 experiences, and 10 million travelers worldwide, with a strong presence in Asia. One of the brands successful implementations was at the Nikko Toshogu Shrine where Rezio was implemented to help with long lines and wait times due to over-tourism. The shrine was able to implement the inventory management features to allow online booking and cashless payments onsite. === FineDayClub === FineDayClub is a membership-based travel concierge service launched in late 2020 by KKday. It is aimed at families, and organizations seeking customized travel experiences. It offers one-on-one advisory services. === ActivityJapan === ActivityJapan is a Japanese comprehensive online travel site that specializes in authentic Japanese travel experiences. It was purchased by KKday in 2021 but continues to operate independently. A computer appliance is a computer system with a combination of hardware, software, or firmware that is specifically designed to provide a particular computing resource. Such devices became known as appliances because of the similarity in role or management to a home appliance, which are generally closed and sealed, and are not serviceable by the user or owner. The hardware and software are delivered as an integrated product and may even be pre-configured before delivery to a customer, to provide a turn-key solution for a particular application. Unlike general purpose computers, appliances are generally not designed to allow the customers to change the software and the underlying operating system, or to flexibly reconfigure the hardware. Another form of appliance is the virtual appliance, which has similar functionality to a dedicated hardware appliance, but is distributed as a software virtual machine image for a hypervisor-equipped device. == Overview == Traditionally, software applications run on top of a general-purpose operating system, which uses the hardware resources of the computer (primarily memory, disk storage, processing power, and networking bandwidth) to meet the computing needs of the user. The main issue with the traditional model is related to complexity. It is complex to integrate the operating system and applications with a hardware platform, and complex to support it afterwards. By tightly constraining the variations of the hardware and software, the appliance becomes easily deployable, and can be used without nearly as wide (or deep) IT knowledge. Additionally, when problems and errors appear, the supporting staff very rarely needs to explore them deeply to understand the matter thoroughly. The staff needs merely training on the appliance management software to be able to resolve most of problems. In all forms of the computer appliance model, customers benefit from easy operations. The appliance has exactly one combination of hardware and operating system and application software, which has been pre-installed at the factory. This prevents customers from needing to perform complex integration work, and dramatically simplifies troubleshooting. In fact, this "turnkey operation" characteristic is the driving benefit that customers seek when purchasing appliances. To be considered an appliance, the (hardware) device needs to be integrated with software, and both are supplied as a package. This distinguishes appliances from "home grown" solutions, or solutions requiring complex implementations by integrators or value-added resellers (VARs). The appliance approach helps to decouple the various systems and applications, for example in the data center. Once a resource is decoupled, in theory it can be also centralized to become shared among many systems, centrally managed and optimized, all without requiring changes to any other system. == Tradeoffs of the computer appliance approach == The major disadvantage of deploying a computer appliance is that since they are designed to supply a specific resource, they most often include a customized operating system running over specialized hardware, neither of which are likely to be compatible with the other systems previously deployed. Customers lose flexibility. One may believe that a proprietary embedded operating system, or operating system within an application, can make the appliance much more secure from common cyber attacks. However, the opposite is true. Security by obscurity is a poor security decision, and appliances are often plagued by security issues as evidenced by the proliferation of IoT devices. == Types of appliances == The variety of computer appliances reflects the wide range of computing resources they provide to applications. Some examples: Storage appliances provide large amounts of storage, often available to many machines on the network. See Network-attached storage and Storage area network. Network appliances are general purpose routers which may also provide firewall protection, Transport Layer Security (TLS), messaging, access to specialized networking protocols (like the ebXML Message Service) and bandwidth multiplexing for the multiple systems they front-end. Backup and disaster recovery appliances computer appliances that are integrated backup software and backup targets, sometimes with hypervisors to support local DR of protected servers. They are often a gateway to a full DRaaS solution. Firewall and Security appliances Dedicated network appliances that are designed to protect computer networks from unwanted traffic. IIoT and MES Gateway appliances Computer appliances that are designed to translate data bidirectionally between control systems and enterprise systems. Proprietary, embedded, firmware applications running on the appliance use point-to-point connections to translate data between field devices in their native automation protocols and MES systems through their APIs, ODBC, or RESTful interfaces. Anti-spam appliances for e-mail spam Software appliances A single application server appliance, with just enough operating system (JeOS) for it to run. Virtual machine appliances consist of a "hypervisor style" embedded operating system running on appliance hardware. The hypervisor layer is matched to the hardware of the appliance, and cannot be varied by the customer, but the customer may load other operating systems and applications onto the appliance in the form of virtual machines. == Consumer appliances == Aside from its deployment within data centers, many computer appliances are directly used by the general public. These include: Digital video recorder Residential gateway Network-attached storage (NAS) Video game console Consumer uses stress the need for an appliance to have easy installation, configuration, and operation, with little or no technical knowledge being necessary. == Appliances in industrial automation == The world of industrial automation has been rich in appliances. These appliances have been hardened to withstand temperature and vibration extremes. These appliances are also highly configurable, enabling customization to meet a wide variety of applications. The key benefits of an appliance in automation are: Reduced downtime - a failed appliance is typically replaced with a COTS replacement and its task is quickly and easily reloaded from a backup. Highly scalable - appliances are typically targeted solutions for an area of a plant or process. As the requirements change, scalability is achieved through the installation of another appliance. Automation concepts are easily replicated throughout the enterprise by standardizing on appliances to perform the needed tasks, as opposed to the development of custom automation schemes for each task. Low TCO (total cost of ownership) - appliances are developed, tested and supported by automation product vendors and undergo a much broader level of quality testing than custom designed automation solutions. The use of appliances in automation reduce the level of testing needed in each individual application. Reduced design time - appliances perform specific functions and although they are highly configurable, they are typically self documenting. This enables appliance based solutions to be transferred from engineer to engineer with minimal need for training and documentation. Types of automation appliances: PLC (programmable logic controller) - Programmable logic controllers are appliances that are typically used for discrete control and offer a wide range of Input and Output options. They are configured through standardized programming languages such as IEC-1131. PID (proportional–integral–derivative controller) - PID controllers are appliances that monitor a process variable and, based on an error term, effect change on a control output (manipulated variable) to drive the process variable to a setpoint. PAC (programmable automation controller) - Programmable automation controllers are appliances that embody properties of both PLCs and PID controllers enabling the integration of both analog and discrete control. Universal gateway - A universal gateway appliance has the ability to communicate with a variety of devices through their respective communication protocols, and will affect data transactions between them. This in increasingly important as manufacturing strives to improve agility, quality, production rates, production costs and reduce downtime through enhanced M2M (machine to machine) communications. EATMs (Enterprise Appliance Transaction Modules) - Enterprise appliance transaction modules are appliances that affect data transactions from plant floor automation systems to enterprise business systems. They communicate to plant floor equipment through various vendor automation protocols, and communicate to business systems through database communication protocols such as JMS (Java Message Service) and SQL (Structured Query Language). == Internal structure == There are several FactorDaily is an Indian digital media publication founded in 2016 by Pankaj Mishra and Jayadevan PK. Mishra was formerly an Editor at TechCrunch and the Economic Times. The digital publication was launched with an intent to produce stories on the impact of technology on life in India. == History == FactorDaily began publishing in May 2016, with daily reported stories on technology, culture and life in India. Prior to its launch, the company had raised $1 million in seed funding from Accel India, Blume Ventures, Girish Mathrubootham of Freshdesk, Vijay Shekhar Sharma of PayTm, and Jay Vijayan of Tekion. Josey Puliyenthuruthel John, formerly Managing Editor at Business Today and National Corporate Editor at Mint, later joined the company as a Consulting Editor. In January 2017, FactorDaily launched its first Podcast called The Outliers. The inaugural episode featured a conversation with Manish Sharma of Printo on his journey starting up. == Awards == The FactorDaily team won the Bengaluru Editors Lab 2017, a journalism hackathon organised by the Global Editors Network (GEN). The story titled "India has 3,800 psychiatrists for 1.2bn people. Can tech step in to manage mental health?" won the first prize in the online category of the fifth Schizophrenia Research Foundation’s (SCARF) ‘Media for Mental Health’ awards. The story titled 'The dark hand of tech that stokes sex trafficking in India', won the Stop Slavery media Awards by the Thomson Reuters Foundation for the year 2020.Single address space operating system
Digital anthropology
KKday
Computer appliance
FactorDaily