Maike Osborne

Maike Osborne

Maike Osborne (born Michael Osborne, 1982) is an Australian academic and scientist who serves as a professor of machine learning at University of Oxford in the Machine Learning Research Group in the Department of Engineering Science. In 2016 she co-founded Mind Foundry, an artificial intelligence company, along with fellow professor Stephen Roberts. == Education == She has a BEng in Mechanical Engineering and a BSc in both Pure Mathematics and Physics from the University of Western Australia. She has a PhD in Machine Learning from the University of Oxford. == Career == Osborne has contributed to over 100 publications, and her work has received over 24,000 citations with an h-index of 46 according to Google Scholar. and has acted as principal or co-investigator for £10.6M of research funding. Her career has focused in particular on Bayesian approaches to AI and machine learning, named after the famous British statistician Thomas Bayes. Osborne's work has contributed to Probabilistic numerics, with Osborne co-authoring the first textbook on the subject. In 2013, Osborne co-authored a paper alongside Swedish-German economist Carl Benedikt Frey called "The Future of Employment: How Susceptible are Jobs to Computerisation?". The paper has received over 13,000 citations and extensive media coverage. In 2023 Osborne gave oral evidence to the UK House of Commons Science and Technology Committee on the subject of the "Governance of Artificial Intelligence". Her testimony received significant coverage around her warnings of the threat of "rogue AI". == Honors == She is also an Official Fellow of Exeter College, and St Peter's College, Oxford, a Fellow of the ELLIS society, and a Faculty Member of the Oxford-Man Institute of Quantitative Finance. She joined the Oxford Martin School as Lead Researcher on the Oxford Martin Programme on Technology and Employment in 2015. She is a Director of the EPSRC Centre for Doctoral Training in Autonomous Intelligent Machines and Systems.

Douglas Parkhill

Douglas F. Parkhill is a Canadian technologist and former research minister, best known for his pioneering work on what is now called cloud computing, and his work on Canada's Telidon videotex project. He started working at the Canadian ministry of Communications (now part of the Department of Trade and Industry) in 1969, having previously worked at the Mitre Corporation. He was responsible for many activities in communications satellites, computer communications, command and control systems and telecommunications. He was winner of the Treasury Board of Canada Secretariat's Outstanding Achievement award in 1982, the Conestoga shield for services to government and industry in computer communications research and development, the Touche Ross award for Telidon development. He was an author of several publications including the 1966 book, The Challenge of the Computer Utility. In the book, Parkhill thoroughly explored many of the modern-day characteristics of cloud computing (elastic provisioning through a utility service) as well as the comparison to the electricity industry and the use of public, private, government and community forms. The book won the McKinsey Foundation award for distinguished contributions to management literature. He worked with Dave Godfrey, the Canadian writer and novelist on a later book Gutenberg two about the social and political meaning of computer technology. He was in charge of research at the Federal Department of Communications at the time when the department was funding development of the Telidon videotext system, was heavily involved in promoting the system, and had overall control of the program. In a radio broadcast in 1980, he outlined some of the potential of the system, from financial information, to theatre reservations, with the ability to pay and print out tickets from the system. He later documented the history of the Telidon project, and the history of videotext in general. == Publications == The Challenge of the Computer Utility, Addison-Wesley, 1966, ISBN 0-201-05720-4 edited with Dave Godfrey, Gutenberg Two: The New Electronics and Social Change, Press Porcepic, 1979, ISBN 0-88878-191-1 The Beginning of a Beginning. Ottawa; Department of Communications, 1987. A history of the Telidon project.

Semantic analysis (machine learning)

In machine learning, semantic analysis of a text corpus is the task of building structures that approximate concepts from a large set of documents. It generally does not involve prior semantic understanding of the documents. Semantic analysis strategies include: Metalanguages based on first-order logic, which can analyze the speech of humans. Understanding the semantics of a text is symbol grounding: if language is grounded, it is equal to recognizing a machine-readable meaning. For the restricted domain of spatial analysis, a computer-based language understanding system was demonstrated. Latent semantic analysis (LSA), a class of techniques where documents are represented as vectors in a term space. A prominent example is probabilistic latent semantic analysis (PLSA). Latent Dirichlet allocation, which involves attributing document terms to topics. n-grams and hidden Markov models, which work by representing the term stream as a Markov chain, in which each term is derived from preceding terms. == Stochastic semantic analysis ==

Artificial Inventor Project

The Artificial Inventor Project (AIP) is a global legal initiative headed by Professor Ryan Abbott dedicated to pursuing intellectual property (IP) rights for inventions and creative works generated autonomously by artificial intelligence (AI) systems without traditional human inventorship or authorship. The project coordinates a series of pro bono test cases worldwide, aiming to prompt law reform and public debate on how IP law should accommodate non-human creators. == History == In 2019, AIP filed patent applications in multiple jurisdictions, including the United States, United Kingdom, European Patent Office, Australia, Switzerland, and South Africa, naming the AI system DABUS (Device for the Autonomous Bootstrapping of Unified Sentience), created by Stephen Thaler, as the inventor. The aim was to challenge legal norms that require inventors to be natural persons and highlight pressing policy questions about AI-generated innovation and IP regimes. == Legal proceedings by jurisdiction == === Australia === In July 2021, a Federal Court of Australia judge (Beach J) ruled that AI can be considered an inventor under the Patents Act 1990, ordering IP Australia to reinstate the relevant patent. However, the full court then overturned this ruling on appeal and denied further review. === European Patent Office === The EPO Board of Appeal determined in 2022 that only a human inventor may be named, rendering DABUS‑based applications unacceptable. === South Africa === In 2021, a patent was granted listing DABUS as the inventor. As South Africa’s procedural system does not involve substantive inventorship review, the grant proceeded on formal grounds alone. === Switzerland === On 26 June 2025, the Swiss Federal Administrative Court ruled that artificial intelligence systems such as DABUS cannot be listed as inventors on patent applications. The court upheld the existing practice of the Swiss Federal Institute of Intellectual Property (IPI), affirming that only natural persons may be recognized as inventors under Swiss patent law. === United Kingdom === In December 2023, the UK Supreme Court unanimously held that AI systems cannot be legally recognized as inventors, affirming that "an inventor must be a person" under current British law. === United States === In Thaler v. Hirshfeld (2021), a U.S. federal court agreed with the USPTO that inventors must be natural persons, rejecting the DABUS application and setting a precedent consistent with existing statute and administrative policy. == Criticism and impact == The project has fueled substantial discourse. Critics caution that allowing AI inventorship may complicate notions of accountability and ownership. Proponents argue that legal recognition must evolve to avoid disincentivizing innovation produced by AI and to maintain honesty about the true source of invention.

Embedding (machine learning)

In machine learning, embedding is a representation learning technique that maps complex, high-dimensional data into a lower-dimensional vector space of numerical vectors. == Technique == It also denotes the resulting representation, where meaningful patterns or relationships are preserved. As a technique, it learns these vectors from data like words, images, or user interactions, differing from manually designed methods such as one-hot encoding. This process reduces complexity and captures key features without needing prior knowledge of the domain. == Similarity == In natural language processing, words or concepts may be represented as feature vectors, where similar concepts are mapped to nearby vectors. The resulting embeddings vary by type, including word embeddings for text (e.g., Word2Vec), image embeddings for visual data, and knowledge graph embeddings for knowledge graphs, each tailored to tasks like NLP, computer vision, or recommendation systems. This dual role enhances model efficiency and accuracy by automating feature extraction and revealing latent similarities across diverse applications. To measure the distance between two embeddings, a similarity measure can be used to find the overall similarity of the concepts represented by the embeddings. If the vectors are normalized to have a magnitude of 1, then the similarity measures are proportional to cos ⁡ ( θ a b ) {\displaystyle \cos \left(\theta _{ab}\right)} . The cosine similarity disregards the magnitude of the vector when determining similarity, so it is less biased towards training data that appears very frequently. The dot product includes the magnitude inherently, so it will tend to value more popular data. Generally, for high-dimensional vector spaces, vectors tend to converge in distance, so Euclidean distance becomes less reliable for large embedding vectors.

Wetware computer

A wetware computer is an organic computer (which can also be known as an artificial organic brain or a neurocomputer) composed of organic material "wetware" such as "living" neurons. Wetware computers composed of neurons are different than conventional computers because they use biological materials, and offer the possibility of substantially more energy-efficient computing. While a wetware computer is still largely conceptual, there has been limited success with construction and prototyping, which has acted as a proof of the concept's realistic application to computing in the future. The most notable prototypes have stemmed from the research completed by biological engineer William Ditto during his time at the Georgia Institute of Technology. His work constructing a simple neurocomputer capable of basic addition from leech neurons in 1999 was a significant discovery for the concept. This research was a primary example driving interest in creating these artificially constructed, but still organic brains. == Origins and theoretical foundations == The term wetware came from cyberpunk fiction, notably through Gibson's Neuromancer, but was quickly taken up in scientific literature to explain computation by biological material. Theories of early biological computation borrowed from Alan Turing's morphogenesis model, which showed that chemical interactions could produce complex patterns without centralized control. Hopfield's associative memory networks also provided a foundation for biological information systems with fault tolerance and self-organization. == Major characteristics and processes == Biological wetware systems demonstrate dynamic reconfigurability underpinned by neuroplasticity and enable continuous learning and adaptation. Reaction-diffusion-based computing and molecular logic gates allow spatially parallel information processing unachievable in conventional systems. These systems also show fault tolerance and self-repair at the cellular and network level. The development of cerebral organoids—miniature lab-grown brains—demonstrates spontaneous learning behavior and suggests biological tissue as a viable computational substrate. == Overview == The concept of wetware is an application of specific interest to the field of computer manufacturing. Moore's law, which states that the number of transistors which can be placed on a silicon chip is doubled roughly every two years, has acted as a goal for the industry for decades, but as the size of computers continues to decrease, the ability to meet this goal has become more difficult, threatening to reach a plateau. Due to the difficulty in reducing the size of computers because of size limitations of transistors and integrated circuits, wetware provides an unconventional alternative. A wetware computer composed of neurons is an ideal concept because, unlike conventional materials which operate in binary (on/off), a neuron can shift between thousands of states, constantly altering its chemical conformation, and redirecting electrical pulses through over 200,000 channels in any of its many synaptic connections. Because of this large difference in the possible settings for any one neuron, compared to the binary limitations of conventional computers, the space limitations are far fewer. == Background == The concept of wetware is distinct and unconventional and draws slight resonance with both hardware and software from conventional computers. While hardware is understood as the physical architecture of traditional computational devices, comprising integrated circuits and supporting infrastructure, software represents the encoded architecture of storage and instructions. Wetware is a separate concept that uses the formation of organic molecules, mostly complex cellular structures (such as neurons), to create a computational device such as a computer. In wetware, the ideas of hardware and software are intertwined and interdependent. The molecular and chemical composition of the organic or biological structure would represent not only the physical structure of the wetware but also the software, being continually reprogrammed by the discrete shifts in electrical pulses and chemical concentration gradients as the molecules change their structures to communicate signals. The responsiveness of a cell, proteins, and molecules to changing conformations, both within their structures and around them, ties the idea of internal programming and external structure together in a way that is alien to the current model of conventional computer architecture. The structure of wetware represents a model where the external structure and internal programming are interdependent and unified; meaning that changes to the programming or internal communication between molecules of the device would represent a physical change in the structure. The dynamic nature of wetware borrows from the function of complex cellular structures in biological organisms. The combination of "hardware" and "software" into one dynamic, and interdependent system which uses organic molecules and complexes to create an unconventional model for computational devices is a specific example of applied biorobotics. === The cell as a model of wetware === Cells in many ways can be seen as their form of naturally occurring wetware, similar to the concept that the human brain is the preexisting model system for complex wetware. In his book Wetware: A Computer in Every Living Cell (2009) Dennis Bray explains his theory that cells, which are the most basic form of life, are just a highly complex computational structure, like a computer. To simplify one of his arguments a cell can be seen as a type of computer, using its structured architecture. In this architecture, much like a traditional computer, many smaller components operate in tandem to receive input, process the information, and compute an output. In an overly simplified, non-technical analysis, cellular function can be broken into the following components: Information and instructions for execution are stored as DNA in the cell, RNA acts as a source for distinctly encoded input, processed by ribosomes and other transcription factors to access and process the DNA and to output a protein. Bray's argument in favor of viewing cells and cellular structures as models of natural computational devices is important when considering the more applied theories of wetware to biorobotics. === Biorobotics === Wetware and biorobotics are closely related concepts, which both borrow from similar overall principles. A biorobotic structure can be defined as a system modeled from a preexisting organic complex or model such as cells (neurons) or more complex structures like organs (brain) or whole organisms. Unlike wetware, the concept of biorobotics is not always a system composed of organic molecules, but instead could be composed of conventional material which is designed and assembled in a structure similar or derived from a biological model. Biorobotics have many applications and are used to address the challenges of conventional computer architecture. Conceptually, designing a program, robot, or computational device after a preexisting biological model such as a cell, or even a whole organism, provides the engineer or programmer the benefits of incorporating into the structure the evolutionary advantages of the model. == Effects on users == Wetware technologies such as BCIs and neuromorphic chips offer new possibilities for user autonomy. For those with disabilities, such systems could restore motor or sensory functions and enhance quality of life. However, these technologies raise ethical questions: cognitive privacy, consent over biological data, and risk of exploitation. Without proper oversight, wetware technologies may also widen inequality, favoring those with access to cognitive enhancements. Open governance frameworks and ethical AI design grounded in neuro ethics will be essential. With the development of wetware devices, disparities in access could exacerbate social inequalities, benefiting those who have resources to enhance cognitive or physical abilities. It is necessary to create strong ethical frameworks, inclusive development practices, and open systems of governance to reduce risks and make sure that wetware advances are beneficial to all segments of society. == Applications and goals == === Basic neurocomputer composed of leech neurons === In 1999 William Ditto and his team of researchers at Georgia Institute of Technology and Emory University created a basic form of a wetware computer capable of simple addition by harnessing leech neurons. Leeches were used as a model organism due to the large size of their neuron, and the ease associated with their collection and manipulation. However, these results have never been published in a peer-reviewed journal, prompting questions about the validity of the claims. The computer was able to complete basic addition through electrical probes

Solomonoff's theory of inductive inference

Solomonoff's theory of inductive inference proves that, under its common sense assumptions (axioms), the best possible scientific model is the shortest algorithm that generates the empirical data under consideration. In addition to the choice of data, other assumptions are that, to avoid the post-hoc fallacy, the programming language must be chosen prior to the data and that the environment being observed is generated by an unknown algorithm. This is also called a theory of induction. Due to its basis in the dynamical (state-space model) character of Algorithmic Information Theory, it encompasses statistical as well as dynamical information criteria for model selection. It was introduced by Ray Solomonoff, based on probability theory and theoretical computer science. In essence, Solomonoff's induction derives the posterior probability of any computable theory, given a sequence of observed data. This posterior probability is derived from Bayes' rule and some universal prior, that is, a prior that assigns a positive probability to any computable theory. Solomonoff proved that this induction is incomputable (or more precisely, lower semi-computable), but noted that "this incomputability is of a very benign kind", and that it "in no way inhibits its use for practical prediction" (as it can be approximated from below more accurately with more computational resources). It is only "incomputable" in the benign sense that no scientific consensus is able to prove that the best current scientific theory is the best of all possible theories. However, Solomonoff's theory does provide an objective criterion for deciding among the current scientific theories explaining a given set of observations. Solomonoff's induction naturally formalizes Occam's razor by assigning larger prior credences to theories that require a shorter algorithmic description. == Origin == === Philosophical === The theory is based in philosophical foundations, and was founded by Ray Solomonoff around 1960. It is a mathematically formalized combination of Occam's razor and the Principle of Multiple Explanations. All computable theories which perfectly describe previous observations are used to calculate the probability of the next observation, with more weight put on the shorter computable theories. Marcus Hutter's universal artificial intelligence builds upon this to calculate the expected value of an action. === Principle === Solomonoff's induction has been argued to be the computational formalization of pure Bayesianism. To understand, recall that Bayesianism derives the posterior probability P [ T | D ] {\displaystyle \mathbb {P} [T|D]} of a theory T {\displaystyle T} given data D {\displaystyle D} by applying Bayes rule, which yields P [ T | D ] = P [ D | T ] P [ T ] P [ D | T ] P [ T ] + ∑ A ≠ T P [ D | A ] P [ A ] {\displaystyle \mathbb {P} [T|D]={\frac {\mathbb {P} [D|T]\mathbb {P} [T]}{\mathbb {P} [D|T]\mathbb {P} [T]+\sum _{A\neq T}\mathbb {P} [D|A]\mathbb {P} [A]}}} where theories A {\displaystyle A} are alternatives to theory T {\displaystyle T} . For this equation to make sense, the quantities P [ D | T ] {\displaystyle \mathbb {P} [D|T]} and P [ D | A ] {\displaystyle \mathbb {P} [D|A]} must be well-defined for all theories T {\displaystyle T} and A {\displaystyle A} . In other words, any theory must define a probability distribution over observable data D {\displaystyle D} . Solomonoff's induction essentially boils down to demanding that all such probability distributions be computable. Interestingly, the set of computable probability distributions is a subset of the set of all programs, which is countable. Similarly, the sets of observable data considered by Solomonoff were finite. Without loss of generality, we can thus consider that any observable data is a finite bit string. As a result, Solomonoff's induction can be defined by only invoking discrete probability distributions. Solomonoff's induction then allows to make probabilistic predictions of future data F {\displaystyle F} , by simply obeying the laws of probability. Namely, we have P [ F | D ] = E T [ P [ F | T , D ] ] = ∑ T P [ F | T , D ] P [ T | D ] {\displaystyle \mathbb {P} [F|D]=\mathbb {E} _{T}[\mathbb {P} [F|T,D]]=\sum _{T}\mathbb {P} [F|T,D]\mathbb {P} [T|D]} . This quantity can be interpreted as the average predictions P [ F | T , D ] {\displaystyle \mathbb {P} [F|T,D]} of all theories T {\displaystyle T} given past data D {\displaystyle D} , weighted by their posterior credences P [ T | D ] {\displaystyle \mathbb {P} [T|D]} . === Mathematical === The proof of the "razor" is based on the known mathematical properties of a probability distribution over a countable set. These properties are relevant because the infinite set of all programs is a denumerable set. The sum S of the probabilities of all programs must be exactly equal to one (as per the definition of probability) thus the probabilities must roughly decrease as we enumerate the infinite set of all programs, otherwise S will be strictly greater than one. To be more precise, for every ϵ {\displaystyle \epsilon } > 0, there is some length l such that the probability of all programs longer than l is at most ϵ {\displaystyle \epsilon } . This does not, however, preclude very long programs from having very high probability. Fundamental ingredients of the theory are the concepts of algorithmic probability and Kolmogorov complexity. The universal prior probability of any prefix p of a computable sequence x is the sum of the probabilities of all programs (for a universal computer) that compute something starting with p. Given some p and any computable but unknown probability distribution from which x is sampled, the universal prior and Bayes' theorem can be used to predict the yet unseen parts of x in optimal fashion. == Mathematical guarantees == === Solomonoff's completeness === The remarkable property of Solomonoff's induction is its completeness. In essence, the completeness theorem guarantees that the expected cumulative errors made by the predictions based on Solomonoff's induction are upper-bounded by the Kolmogorov complexity of the (stochastic) data generating process. The errors can be measured using the Kullback–Leibler divergence or the square of the difference between the induction's prediction and the probability assigned by the (stochastic) data generating process. === Solomonoff's uncomputability === Unfortunately, Solomonoff also proved that Solomonoff's induction is uncomputable. In fact, he showed that computability and completeness are mutually exclusive: any complete theory must be uncomputable. The proof of this is derived from a game between the induction and the environment. Essentially, any computable induction can be tricked by a computable environment, by choosing the computable environment that negates the computable induction's prediction. This fact can be regarded as an instance of the no free lunch theorem. == Modern applications == === Artificial intelligence === Though Solomonoff's inductive inference is not computable, several AIXI-derived algorithms approximate it in order to make it run on a modern computer. The more computing power they are given, the closer their predictions are to the predictions of inductive inference (their mathematical limit is Solomonoff's inductive inference). Another direction of inductive inference is based on E. Mark Gold's model of learning in the limit from 1967 and has developed since then more and more models of learning. The general scenario is the following: Given a class S of computable functions, is there a learner (that is, recursive functional) which for any input of the form (f(0),f(1),...,f(n)) outputs a hypothesis (an index e with respect to a previously agreed on acceptable numbering of all computable functions; the indexed function may be required consistent with the given values of f). A learner M learns a function f if almost all its hypotheses are the same index e, which generates the function f; M learns S if M learns every f in S. Basic results are that all recursively enumerable classes of functions are learnable while the class REC of all computable functions is not learnable. Many related models have been considered and also the learning of classes of recursively enumerable sets from positive data is a topic studied from Gold's pioneering paper in 1967 onwards. A far reaching extension of the Gold’s approach is developed by Schmidhuber's theory of generalized Kolmogorov complexities, which are kinds of super-recursive algorithms.