Cloudflare, Inc., is an American technology company headquartered in San Francisco, California, that provides a range of internet services, including content delivery network (CDN) services, cloud cybersecurity, DDoS mitigation, and ICANN-accredited domain registration. The company's services act primarily as a reverse proxy between website visitors and a customer's hosting provider, improving performance and protecting against malicious traffic. Cloudflare was founded in 2009 by Matthew Prince, Lee Holloway, and Michelle Zatlyn. The company went public on the New York Stock Exchange in 2019 under the ticker symbol NET. Cloudflare has since expanded its offerings to include edge computing through its Workers platform, a public DNS resolver (1.1.1.1), and a VPN-like service known as WARP. In recent years, the company has integrated artificial intelligence into its infrastructure, acquiring companies such as Replicate and launching tools to manage AI bots and scrapers. According to W3Techs, Cloudflare is used by approximately 21.3% of all websites on the Internet as of January 2026. The company has been the subject of controversy regarding its policy of content neutrality. While Cloudflare executives have historically advocated for remaining a neutral infrastructure provider, the company has terminated services for specific high-profile websites associated with hate speech and violence, including The Daily Stormer, 8chan, and Kiwi Farms, following significant public pressure. Cloudflare has also faced criticism and litigation regarding copyright infringement by websites using its services, notably losing a lawsuit against Japanese publishers in 2025. The company experienced significant global outages in late 2025 which disrupted services for major platforms internationally. == History == Cloudflare was founded on July 26, 2009, by Matthew Prince, Lee Holloway, and Michelle Zatlyn. Prince and Holloway had previously collaborated on Project Honey Pot, a product of Unspam Technologies that partly inspired the basis of Cloudflare. In 2009, the company was venture-capital funded. On August 15, 2019, Cloudflare submitted its S-1 filing for an initial public offering on the New York Stock Exchange under the stock ticker NET. It opened for public trading on September 13, 2019, at $15 per share. According to the company, the name 'Cloudflare' was chosen, over the initial 'WebWall', because it best described what they were trying to do: build a "firewall in the cloud." In 2020, Cloudflare co-founder and COO Michelle Zatlyn was named president. Cloudflare has acquired web-services and security companies, including StopTheHacker (February 2014), CryptoSeal (June 2014), Eager Platform Co. (December 2016), Neumob (November 2017), S2 Systems (January 2020), Linc (December 2020), Zaraz (December 2021), Vectrix (February 2022), Area 1 Security (February 2022), Nefeli Networks (March 2024), BastionZero (May 2024), and Kivera (October 2024). Replicate (November 2025), and Human Native (January 2026). Since at least 2017, Cloudflare has used a wall of lava lamps at its San Francisco headquarters as a source of randomness for encryption keys, alongside double pendulums at its London offices and a Geiger counter at its Singapore offices. The lava lamp installation implements the Lavarand method, where a camera transforms the unpredictable shapes of the "lava" blobs into a digital image. In Q4 2022, Cloudflare provided paid services to 162,086 customers. In October 2024, Cloudflare won a lawsuit against patent troll Sable Networks. Sable paid Cloudflare $225,000, granted it a royalty-free license to its patent portfolio, and dedicated its patents to the public by abandoning its patent rights. In November 2025, it was announced Cloudflare had agreed to acquire Replicate, a San Francisco–based platform that enables software developers to run, fine-tune, and deploy open-source machine-learning models via an API without managing infrastructure. In January 2026, Cloudflare released an analysis regarding BGP routing leaks observed from the Venezuelan state-owned ISP CANTV (AS8048), which occurred on January 2 coincides with the arrest of Nicolás Maduro. While some security researchers had speculated that the outages were linked to U.S. cyber operations, Cloudflare's data indicated that the anomalies were consistent with a pattern of "insufficient routing export and import policies" by the ISP rather than malicious external interference. In January 2026, Cloudflare acquired Human Native, an AI data marketplace that brokers transactions between developers and content creators, for an undisclosed amount. On January 16, 2026, Cloudflare acquired The Astro Technology Company, the developers behind the open-source web framework Astro. In May 2026, Cloudflare announced the elimination of approximately 1,100 positions, around 20 percent of its workforce, in a restructuring the company attributed to the rapid adoption of artificial intelligence tools. The announcement coincided with the company's first-quarter 2026 earnings, which reported a record $639.8 million in quarterly revenue, a 34 percent year-over-year increase. CEO Matthew Prince stated the cuts were not driven by performance concerns but reflected roles made obsolete by AI, and that Cloudflare expected to employ more people by the end of 2027 than at any point during 2026. == Products == Cloudflare provides network and security products for consumers and businesses, utilizing edge computing, reverse proxies for web traffic, data center interconnects, and a content distribution network to serve content across its network of servers. It supports transport layer protocols TCP, UDP, QUIC, and many application layer protocols such as DNS over HTTPS, SMTP, and HTTP/2 with support for HTTP/2 Server Push. As of 2023, Cloudflare handles an average of 45 million HTTP requests per second. As of 2024, Cloudflare servers are powered by AMD EPYC 9684X processors. Cloudflare also provides analysis and reports on large-scale outages, including Verizon's October 2024 outage. === Artificial intelligence === In 2023, Cloudflare launched "Workers AI", a framework allowing for use of Nvidia GPU's within Cloudflare's network. In 2024, Cloudflare launched a tool that prevents bots from scraping websites. To build automatic bot detector models, the company analyzed "AI" bots and crawler traffic. The company also launched an "AI" assistant to generate charts based on queries by leveraging "Workers AI". Cloudflare announced plans in September 2024 to launch a marketplace where website owners can sell "AI" model providers access to scrape their site's content. In March 2025, Cloudflare announced a new feature called "AI Labyrinth", which combats unauthorized "AI" data scraping by serving fake "AI"-generated content to LLM bots. In July, the company rolled out a permission-based setting to allow websites to automatically block online bots from scraping data and content. Cloudflare released AutoRAG into beta in 2025. AutoRAG (retrieval augmented generation) creates a vector database of a website's unstructured content to identify relationships between concepts. It is part of an initiative with Microsoft, alongside their NLWeb standard, to make websites easier for people and automated systems to query. Cloudflare and GoDaddy partnered in April 2026 to enable AI Crawl Control features on GoDaddy hosted websites. This would allow site owners to decide how AI bot crawlers interact with their content. === DDoS mitigation === Cloudflare provides free and paid DDoS mitigation services that protect customers from distributed denial of service (DDoS) attacks. Cloudflare received media attention in June 2011 for providing DDoS mitigation for the website of LulzSec, a black hat hacking group. In March 2013, The Spamhaus Project was targeted by a DDoS attack that Cloudflare reported exceeded 300 gigabits per second (Gbit/s). Patrick Gilmore, of Akamai, stated that at the time it was "the largest publicly announced DDoS attack in the history of the Internet". While trying to defend Spamhaus against the DDoS attacks, Cloudflare ended up being attacked as well; Google and other companies eventually came to Spamhaus' defense and helped it to absorb the unprecedented amount of attack traffic. In 2014, Cloudflare began providing free DDoS mitigation for artists, activists, journalists, and human rights groups under the name "Project Galileo". In 2017, it extended the service to electoral infrastructure and political campaigns under the name "Athenian Project". By 2025, more than 2,900 users and organizations were participating in Project Galileo, including 31 US states. In February 2014, Cloudflare claimed to have mitigated an NTP reflection attack against an unnamed European customer, which it stated peaked at 400 Gbit/s. In November 2014, it reported a 500 Gbit/s DDoS attack in Hong Kong. In July 2021, the company claimed to have absorbed a DDoS atta
Showcase Workshop
Showcase Workshop, also referred to as Showcase, is a SaaS company that develops a presentation-building application for business use. Users upload files and images to a web platform which generates presentations viewable on a suite of mobile apps. Showcase was founded in 2011. The company’s headquarters are in Wellington, New Zealand. == History == Showcase Workshop was originally developed in response to dynamically changing content being presented on iPads at the 2012 Olympics. After market-testing a beta version of the core application, Showcase Workshop launched commercially in 2012. In 2014 Showcase partnered with Vodafone Global Enterprise. == Product == Users upload pre-existing PDFs, videos, images and Microsoft Office documents to a secure server, building presentations or ‘showcases’ which can then be downloaded via the mobile apps. The presentations are used for mobile sales enablement, training, or operational/health and safety purposes. == Reception == Reviewers have praised the ease of use of Showcase, calling it a “better alternative to developing a native app” and “intuitive”. Criticisms include the lack of differing templates and a lack of complex customisation controls. Showcase was nominated for a Tabby Award in 2014 and won a Tabby Award in 2015 for its Windows app.
Eimear Kenny
Eimear E. Kenny is a researcher in population genetics and translation genomics, and is the Founding Director of the Institute for Genomic Health, and Endowed Chair and Professor of Genomic Health at the Icahn School of Medicine at Mount Sinai. She is known for novel approaches in computational genomics, advancing the study of human genetic variation and its connection to disease risk and diagnosis. Her research has laid the foundation for integrating artificial intelligence (AI) and genomics into precision medicine and routine clinical care. By combining genomics, computer science, and medicine, her work leverages genomic sequencing technologies and machine learning algorithms to uncover insights that improve patient care, accelerate genomic data analysis, and enable the future of AI-driven healthcare. She has led multiple genomics-based clinical trials, applying computational biology and AI in clinical settings to advance genomic medicine and precision healthcare. == Research == A recipient of the Early-Career Award from the American Society of Human Genetics (USA), Kenny, as of 2024, leads a team in genetics, computer science, and medicine, focusing on genetic ancestry, large-scale genomics, clinical trials, and genomic medicine at the Institute for Genomic Health. The lab works to advance understanding of genetic ancestry and its impact on health in order to inform better clinical medicine models. She is recognized for her work to leverage biobanks for translational genomics and her development of new genetic tests an strategies for health care management. In one study, she and her colleagues investigated genetic disorders that might be under-diagnosed due to insufficient data, and found a variant in a collagen gene associated with Steel syndrome. This syndrome caused short stature and bone and joint issues and was thought to be rare. However, the study revealed it is common in individuals with Puerto Rican ancestry. Three of Kenny's genomic medicine clinical trials assessed how to bring new technology, such as digital apps, or information, such as polygenic risk scores, into routine clinical care. In the 2010s, Kenny was instrumental in several large-scale sequencing studies, including the 1000 Genomes Project, the Exome Sequencing Project, the Genome Sequencing Project, and the Trans-Omics for Precision Medicine. In 2012, she led work that discovered the variant responsible for blond hair in Melanesia, work that was featured in the Smithsonian NHGRI Human Genome Exhibit in Washington, D.C. In 2017, her group was one of the first to demonstrate that polygenic risk scores derived in predominantly European populations have reduced accuracy when applied in populations now widely acknowledged as a major challenge in the field of genomic risk prediction. As of 2024, she is Principal Investigator in many NIH-funded international consortium focused on computational genomics and genomic medicine, including Electronic Medical Records and Genomics, Polygenic Risk Methods in Diverse Populations, and the Human Pangenome Reference Consortium. In 2023, Kenny played a key role in a groundbreaking advancement in genomics research by helping to map a diverse human pangenome—a major shift from reliance on a single reference genome. Unlike the earlier genetic map, based on one man of mixed European and African ancestry in Buffalo, this new pangenome project captures far greater human genetic diversity. As reported by The Washington Post, Kenny's work demonstrates how a more inclusive human genome can drive discoveries in rare genetic diseases, improve genomic medicine, and accelerate the future of precision healthcare. Kenny was co-developer and current license holder for Random Forest adMIXture (RFMix), a patented software for inferring continental and sub-continental ancestry at genomic loci. == Education and career == Kenny graduated from Trinity College Dublin with a BA in Biochemistry in 1999 and did a masters in Bioinformatics at Leeds University. She received her PhD in Computational Genomics at Rockefeller University, and did her post-doctoral work in the lab of Dr. Carlos D. Bustamante at Stanford University. === Academic appointments === As of 2024, at Mount Sinai, she serves as the Endowed Chair and Professor of Genomic Health, Professor at the Department of Medicine and Professor at the Department of Genetics and Genomic Sciences. Since 2018 she has served as the Founding Director of the Institute for Genomic Health, and since 2022, she also serves as the Founding Director of the Center for Translational Genomics. She is also the Director of Translational Research, Division for Genomic Medicine. Former appointments include Assistant Professor at the Department of Genetics and Genomic Sciences and Member at The Charles Bronfman Institute of Personalized Medicine, both at Mount Sinai. She was also Bioinformatics Programmer at the California Institute of Technology, and research assistant at the Massachusetts Institute of Technology. == Publications == As of 2024, Kenny is an advisor to Cell Genomics. Google Scholar reports 50,623 citations, an h-index of 66 and an i10-index of 130. The five most-cited articles she contributed to are: Auton, A; Brooks, LD; Durbin, RM; Garrison, EP; Kang, HM; Korbel, JO; Marchini, JL; McCarthy, S; McVean, GA; Abecasis, GR (2015). "A global reference for human genetic variation". Nature. 526 (7571): 68–74. Bibcode:2015Natur.526...68T. doi:10.1038/nature15393. PMC 4750478. PMID 26432245.. Cited by 14847 Abecasis, GR; Auton, A; Brooks, LD; DePristo, MA; Durbin, RM; Handsaker, RE; Kang, HM; Marth, GT; McVean, GA (2012). "An integrated map of genetic variation from 1,092 human genomes". Nature. 491 (7422): 56–65. Bibcode:2012Natur.491...56T. doi:10.1038/nature11632. PMC 3498066. PMID 23128226.. Cited by 8287 Jacob A. Tennessen et al. Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes.Science337,64–69(2012).DOI:10.1126/science.1219240 Cited by 1886 Taliun, D.; Harris, D.N.; Kessler, M.D.; et al. (2021). "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program". Nature. 590 (7845): 290–299. Bibcode:2021Natur.590..290T. doi:10.1038/s41586-021-03205-y. PMC 7875770. PMID 33568819.. Cited by 1369 Vilhjálmsson, BJ; et al. (2015). "Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores". Am J Hum Genet. 97 (4): 576–92. doi:10.1016/j.ajhg.2015.09.001. PMC 4596916. PMID 26430803.. Cited by 1327
GENESIS (software)
GENESIS (The General Neural Simulation System) is a simulation environment for constructing realistic models of neurobiological systems at many levels of scale including: sub-cellular processes, individual neurons, networks of neurons, and neuronal systems. These simulations are “computer-based implementations of models whose primary objective is to capture what is known of the anatomical structure and physiological characteristics of the neural system of interest”. GENESIS is intended to quantify the physical framework of the nervous system in a way that allows for easy understanding of the physical structure of the nerves in question. “At present only GENESIS allows parallelized modeling of single neurons and networks on multiple-instruction-multiple-data parallel computers.” Development of GENESIS software spread from its home at Caltech to labs at the University of Texas at San Antonio, the University of Antwerp, the National Centre for Biological Sciences in Bangalore, the University of Colorado, the Pittsburgh Supercomputing Center, the San Diego Supercomputer Center, and Emory University. == Neurons and Neural Systems == GENESIS works by creating simulation environments for constructing models of neurons or neural systems. "Nerve cells are capable of communicating with each other in such a highly structured manner as to form neuronal networks. To understand neural networks, it is necessary to understand the ways in which one neuron communicates with another through synaptic connections and the process called synaptic transmission". Neurons have a specialized structure for their function, they "are different from most other cells in the body in that they are polarized and have distinct morphological regions, each with specific functions". The two important regions of a neuron are the dendrite and the axon. "Dendrites are the region where one neuron receives connections from other neurons. The cell body or soma contains the nucleus and the other organelles necessary for cellular function. The axon is a key component of nerve cells over which information is transmitted from one part of the neuron (e.g., the cell body) to the terminal regions of the neuron". The third important piece of a neuron is the synapse. "The synapse is the terminal region of the axon this is where one neuron forms a connection with another and conveys information through the process of synaptic transmission". Neural networks like the ones simulated with GENESIS software can quickly become highly complex and difficult to understand. "Just a few interconnected neurons (a microcircuit) can perform sophisticated tasks such as mediate reflexes, process sensory information, generate locomotion and mediate learning and memory. Even more complex networks, macrocircuits, consist of multiple embedded microcircuits. Macrocircuits mediate higher brain functions such as object recognition and cognition". GENESIS endeavors to simulate neural systems as they are found in nature. Often, "a neuron can receive contacts from up to 10,000 presynaptic neurons, and, in turn, any one neuron can contact up to 10,000 postsynaptic neurons. The combinatorial possibility could give rise to enormously complex neuronal circuits or network topologies, which might be very difficult to understand". == History == GENESIS was developed by Dr. James M. Bower, in the Caltech laboratory, and first released to the public in 1988 in association with the first Methods in Computational Neuroscience Course at the Marine Biological Laboratory in Woods Hole, MA. Full source code for the software was released in the same year under an open software model for development. It's now supported by the Computational Biology Initiative at the University of Texas at San Antonio and is available free along with tutorial guides on its use. P-GENESIS, a parallel version of GENESIS, was first run in 1990 on the Intel Delta, which was the prototype for the Intel Paragon family of massively parallel supercomputers. == How GENESIS Works == GENESIS is useful in creating a simulation environment for constructing models of neurobiological systems, such as: sub-cellular processes individual neurons networks of neurons neuronal systems The GENESIS system is complicated, but relatively easy to use. An individual can input commands through one of three ways: script files, graphical user interface, or the GENESIS command shell. These commands are then processed by the script language interpreter. "The Script Language Interpreter processes commands entered through the keyboard, script files, or the graphical user interface, and passes them to the GENESIS simulation engine. The simulation engine also loads compiled object libraries, reads and writes data files, and interacts with the graphical user interface". Below is a graphical representation of the user input process and a sample GENESIS output. == Applications == Most current applications for GENESIS involve realistic simulations of biological systems. It is usually used to simulate the behavior of larger brain structures, for example the cerebral cortex. These studies most often occur in lab courses in neural simulation at Caltech and the Marine Biological Laboratory at Woods Hole, Massachusetts. GENESIS can be used in combination with Yale University’s software called NEURON as a means for scientists to collaborate to construct a physical description of the nervous system. The GENESIS software can also be used with Kinetikit in the modeling of signal transduction pathways. GENESIS has been used in many studies. Some of these studies involve research that focuses on the development of software that would be useful across many disciplines. Others are studies of neurons, such as Purkinje cells. These studies used GENESIS to simulate Purkinje cells and could be useful for the planning and development of later experiments using the GENESIS software. There may also be biomedical applications of the software. For example, St. Jude Medical in Europe has developed an implanted GENESIS device.
NeOn Toolkit
The NeOn Toolkit is an open source, multi-platform ontology editor, which supports the development of ontologies in F-Logic and OWL/RDF. The editor is based on the Eclipse platform and provides a set of plug-ins (currently 20 plug-ins are available for the latest version, v2.4) covering a number of ontology engineering activities, including Annotation and Documentation, Modularization and Customization, Reuse, Ontology Evolution, translation and others. The NeOn Toolkit has been developed in the course of the EU-funded NeOn project and is currently maintained and distributed by the NeOn Technologies Foundation.
Vatican News App
The Vatican News App is an official mobile application software issued by the Vatican's Dicastery for Communication. Formerly titled The Pope App, the app was launched on January 23, 2013, under the auspices of the Pontifical Council for Social Communications, a now-defunct dicastery that was merged into the Secretariat (now Dicastery) for Communication in March 2016. Initially, The Pope App was available only on iOS devices, but became available for Android phones at the end of February 2013. The app is available for download on iOS and Android in five languages: English, French, Italian, Portuguese and Spanish. It was originally promoted as an application with focus on the figure of the Pope which made it possible to follow the Pope's events while they are taking place. Alerts notified the followers by informing and offering access to "official papal-related content in a variety of formats". The app also enabled its users to see areas of the Vatican through webcams allocated throughout St. Peter's Square in Rome that broadcast images. In early 2018, The Pope App was relaunched as the Vatican News App, accompanied by a redesign that eliminated many of the previous version's features, reducing the app to a more conventional news service, with increased emphasis on news from the Vatican and the worldwide Catholic Church and less focus on the day-to-day activities of the Pope.
Suggested Upper Merged Ontology
The Suggested Upper Merged Ontology (SUMO) is an upper ontology intended as a foundation ontology for a variety of computer information processing systems. SUMO defines a hierarchy of classes and related rules and relationships. These are expressed in a version of the language SUO-KIF, a higher-order logic that has a LISP-like syntax, as well as the TPTP family of languages. A mapping from WordNet synsets to SUMO has been defined. Initially, SUMO was focused on meta-level concepts (general entities that do not belong to a specific problem domain), and thereby would lead naturally to a categorization scheme for encyclopedias. It has now been considerably expanded to include a mid-level ontology and dozens of domain ontologies. SUMO is organized for interoperability of automated reasoning engines. To maximize compatibility, schema designers can try to assure that their naming conventions use the same meanings as SUMO for identical words (for example, "agent" or "process"). SUMO has an associated open source Sigma knowledge engineering environment. Initially, Sumo was developed by the Teknowledge Corporation and now is maintained by Articulate Software. SUMO is open source. The first release was in December 2000.