AI Face Upscale

AI Face Upscale — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

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  Shopify

  Shopify Inc., stylized as shopify, is a Canadian multinational e-commerce company headquartered in Ottawa, Ontario that operates a platform for retail point-of-sale systems. The company has over 5 million customers and processed US$292.3 billion in transactions in 2024, of which 57% was in the United States. Major customers include Tesla, LVMH, Nestlé, PepsiCo, AB InBev, Kraft Heinz, Lindt, Whole Foods Market, Red Bull, and Hyatt. The company's software has been praised for its ease of use and reasonable fee structure. It has been described as the "go-to e-commerce platform for startups". However, the company has faced criticism for allegedly inflating their sales data and for associating with controversial sellers. == History == === 2006: Founding === Shopify was founded in 2006 by friends Tobias Lütke, Daniel Weinand and Scott Lake after launching Snowdevil, an online store for snowboarding equipment, in 2004. Dissatisfied with the existing e-commerce products on the market, Lütke, a computer programmer by trade, instead built his own. Lütke used the open source web application framework Ruby on Rails to build Snowdevil's online store and launched it after two months of development. The Snowdevil founders launched the platform as Shopify in June 2006. Shopify created an open-source template language called Liquid, which is written in Ruby and has been used since 2006. In June 2009, Shopify launched an application programming interface (API) platform and App Store. The API allows developers to create applications for Shopify online stores and then sell them on the Shopify App Store. === 2010s === In January 2010, Shopify started its Build-A-Business competition, in which participants create a business using its commerce platform. The winners of the competition received cash prizes and mentorship from entrepreneurs, such as Richard Branson, Eric Ries and others. In April of that year, Shopify launched a free mobile app on the Apple App Store. The app allows Shopify store owners to view and manage their stores from iOS mobile devices. In December 2010, Shopify raised $7 million from a series A round from Bessemer Venture Partners, FirstMark Capital, and Felicis Ventures at a $20 million pre-money valuation. At that time, the company had annualized transaction value of $132 million. In October 2011, it raised $15 million in a Series B round. In August 2013, Shopify launched Shopify Payments in partnership with Stripe. Shopify Payments allows merchants to accept payments without requiring a third-party payment gateway. The company also announced the launch of a point of sale system to enable in-person sales in addition to online. The company received $100 million in Series C funding in December 2013. Shopify earned $105 million in revenue in 2014, twice as much as it raised the previous year. In February 2014, Shopify released "Shopify Plus" for large e-commerce businesses seeking access to additional features and support. Shopify went public via an initial public offering on May 21, 2015 raising more than $131 million. In September 2015, Amazon.com closed its Amazon Webstore service for merchants and selected Shopify as the preferred migration provider; In April 2016, Shopify announced Shopify Capital, a cash advance product. Shopify Capital was initially piloted to merchants within the US and allowed merchants to receive an advance on future earnings processed through its payment gateway. Since its launch in 2016, Shopify Capital has provided more than $5.1 billion in funding to Shopify merchants, with a maximum advance of $2 million. On June 7, 2016, Shopify launched its Shopify Plus Partners Program, to help agencies connect with evolving businesses in ecommerce space. On October 3, 2016, Shopify acquired Boltmade. In November 2016, Shopify partnered with Paystack which allowed Nigerian online retailers to accept payments from customers around the world. On November 22, 2016, Shopify launched Frenzy, a mobile app that improves flash sales. In January 2017, Shopify announced integration with Amazon that would allow merchants to sell on Amazon from their Shopify stores. In April 2017, Shopify introduced its Chip & Swipe Reader, a Bluetooth enabled debit and credit card reader for brick and mortar retail purchases. The company has since released additional technology for brick and mortar retailers, including a point-of-sale system with a Dock and Retail Stand similar to that offered by Square, and a tappable chip card reader. Shopify announced a one-click accelerated checkout feature called Shopify Pay in April 2017 as an exclusive feature for merchants using Shopify Payments as their payment processor. Customers can save their shipping and payment information for future purchases from all participating Shopify stores. In November 2017 Shopify announced Arrive, a mobile application to help customers track packages from both Shopify merchants and other e-commerce websites. In September 2018, Shopify announced plans to expand its office space in Toronto's King West neighborhood in 2022 as part of "The Well" complex, jointly owned by Allied Properties REIT and RioCan REIT. In October 2018, Shopify opened its first flagship, a physical space for business owners in Los Angeles. The space offered educational classes, coworking space, a "genius bar" for companies that use Shopify software, and workshops. Online cannabis sales in Ontario, Canada, used Shopify's software when the drug was legalized in October 2018. Shopify's software is also used for in-person cannabis sales in Ontario since becoming legal in 2019. In January 2019, Shopify announced the launch of Shopify Studios, a full-service television and film content and production house. On March 22, 2019, Shopify and email marketing platform Mailchimp ended an integration agreement over disputes involving customer privacy and data collection. In April 2019, Shopify announced an integration with Snapchat to allow Shopify merchants to buy and manage Snapchat Story ads directly on the Shopify platform. The company had previously secured similar integration partnerships with Facebook and Google. On August 14, 2019, Shopify launched Shopify Chat, a new native chat function that allows merchants to have real-time conversations with customers visiting Shopify stores online. === 2020s === In January 2020, the company announced plans to hire in Vancouver, Canada. Additionally, the effects of the COVID-19 pandemic contributed to lifting stock prices. On February 21, 2020, Shopify announced plans to join the Diem Association, known as Libra Association at the time. Also that month, Shopify Pay was rebranded as Shop Pay. In April, Arrive was rebranded as Shop, combining both customer-facing features under a single brand. In May, during the COVID-19 pandemic, Shopify announced it would shift most of its global workforce to permanent remote work. It was reported that Shopify's valuation would likely rise on the back of options it had in the company Affirm that was expecting to go public shortly. In November 2020, Shopify announced a partnership with Alipay to support merchants with cross-border payments. Shopify also provided the opportunity for users to connect Alibaba and AliExpress to Shopify through a Alibaba Dropshipping app that could be purchased through the Shopify App Store. Multiple applications launched between 2021 and 2024 allowed customers to connect their Shopify store to their Alibaba account and then import and publish your products. The integration automatically syncs inventory and orders between both platforms so that Alibaba vendors can ship directly to dropshipping customers.As a result of Affirm's January 13, 2021 IPO, Shopify's 8% stake in Affirm was worth $2 billion. About half of Shopify's C-level executives left the company in early 2021. On June 29, 2021, Shopify removed the 20% revenue share for app developers that make less than US$1 million per year. On January 18, 2022, Shopify announced a partnership with JD.com to let U.S. merchants expand their operations in China, listing their products on JD's cross-border e-commerce platform JD Worldwide. On March 22, 2022, Shopify introduced Linkpop, a product to create a branded, social marketplace through which merchants can advertise and market their products via links to be added on social media channels. The following month, Shopify, Alphabet Inc., Meta Platforms, McKinsey & Company, and Stripe, Inc. announced a $925 million advance market commitment of carbon dioxide removal (CDR) from companies that are developing CDR technology over the next 9 years. In June 2022, Shopify partnered with Twitter. As a part of the deal, Twitter announced that it would launch a sales channel app for all of Shopify's U.S. merchants through its app store. Shopify also partnered with PayPal to offer Shopify Payments to merchants in France. On July 26, 2022, Lütke announced immediate layoffs totalling roughly 10 percent of its workforce. In

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  Computational learning theory

  In computer science, computational learning theory (or just learning theory) is a subfield of artificial intelligence devoted to studying the design and analysis of machine learning algorithms. == Overview == Theoretical results in machine learning often focus on a type of inductive learning known as supervised learning. In supervised learning, an algorithm is provided with labeled samples. For instance, the samples might be descriptions of mushrooms, with labels indicating whether they are edible or not. The algorithm uses these labeled samples to create a classifier. This classifier assigns labels to new samples, including those it has not previously encountered. The goal of the supervised learning algorithm is to optimize performance metrics, such as minimizing errors on new samples. In addition to performance bounds, computational learning theory studies the time complexity and feasibility of learning . In computational learning theory, a computation is considered feasible if it can be done in polynomial time . There are two kinds of time complexity results: Positive results – Showing that a certain class of functions is learnable in polynomial time. Negative results – Showing that certain classes cannot be learned in polynomial time. Negative results often rely on commonly believed, but yet unproven assumptions, such as: Computational complexity – P ≠ NP (the P versus NP problem); Cryptographic – One-way functions exist. There are several different approaches to computational learning theory based on making different assumptions about the inference principles used to generalise from limited data. This includes different definitions of probability (see frequency probability, Bayesian probability) and different assumptions on the generation of samples. The different approaches include: Exact learning, proposed by Dana Angluin; Probably approximately correct learning (PAC learning), proposed by Leslie Valiant; VC theory, proposed by Vladimir Vapnik and Alexey Chervonenkis; Inductive inference as developed by Ray Solomonoff; Algorithmic learning theory, from the work of E. Mark Gold; Online machine learning, from the work of Nick Littlestone. While its primary goal is to understand learning abstractly, computational learning theory has led to the development of practical algorithms. For example, PAC theory inspired boosting, VC theory led to support vector machines, and Bayesian inference led to belief networks.

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  Policy gradient method

  Policy gradient methods are a class of reinforcement learning algorithms and a sub-class of policy optimization methods. Unlike value-based methods which learn a value function to derive a policy, policy optimization methods directly learn a policy function π {\displaystyle \pi } that selects actions without consulting a value function. For policy gradient to apply, the policy function π θ {\displaystyle \pi _{\theta }} is parameterized by a differentiable parameter θ {\displaystyle \theta } . == Overview == In policy-based RL, the actor is a parameterized policy function π θ {\displaystyle \pi _{\theta }} , where θ {\displaystyle \theta } are the parameters of the actor. The actor takes as argument the state of the environment s {\displaystyle s} and produces a probability distribution π θ ( ⋅ ∣ s ) {\displaystyle \pi _{\theta }(\cdot \mid s)} . If the action space is discrete, then ∑ a π θ ( a ∣ s ) = 1 {\displaystyle \sum _{a}\pi _{\theta }(a\mid s)=1} . If the action space is continuous, then ∫ a π θ ( a ∣ s ) d a = 1 {\displaystyle \int _{a}\pi _{\theta }(a\mid s)\mathrm {d} a=1} . The goal of policy optimization is to find some θ {\displaystyle \theta } that maximizes the expected episodic reward J ( θ ) {\displaystyle J(\theta )} : J ( θ ) = E π θ [ ∑ t = 0 T γ t R t | S 0 = s 0 ] {\displaystyle J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\gamma ^{t}R_{t}{\Big |}S_{0}=s_{0}\right]} where γ {\displaystyle \gamma } is the discount factor, R t {\displaystyle R_{t}} is the reward at step t {\displaystyle t} , s 0 {\displaystyle s_{0}} is the starting state, and T {\displaystyle T} is the time-horizon (which can be infinite). The policy gradient is defined as ∇ θ J ( θ ) {\displaystyle \nabla _{\theta }J(\theta )} . Different policy gradient methods stochastically estimate the policy gradient in different ways. The goal of any policy gradient method is to iteratively maximize J ( θ ) {\displaystyle J(\theta )} by gradient ascent. Since the key part of any policy gradient method is the stochastic estimation of the policy gradient, they are also studied under the title of "Monte Carlo gradient estimation". == REINFORCE == === Policy gradient === The REINFORCE algorithm, introduced by Ronald J. Williams in 1992, was the first policy gradient method. It is based on the identity for the policy gradient ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t ∣ S t ) ∑ t = 0 T ( γ t R t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})\;\sum _{t=0}^{T}(\gamma ^{t}R_{t}){\Big |}S_{0}=s_{0}\right]} which can be improved via the "causality trick" ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t ∣ S t ) ∑ τ = t T ( γ τ R τ ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau }){\Big |}S_{0}=s_{0}\right]} Thus, we have an unbiased estimator of the policy gradient: ∇ θ J ( θ ) ≈ 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t , n ∣ S t , n ) ∑ τ = t T ( γ τ − t R τ , n ) ] {\displaystyle \nabla _{\theta }J(\theta )\approx {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t,n}\mid S_{t,n})\sum _{\tau =t}^{T}(\gamma ^{\tau -t}R_{\tau ,n})\right]} where the index n {\displaystyle n} ranges over N {\displaystyle N} rollout trajectories using the policy π θ {\displaystyle \pi _{\theta }} . The score function ∇ θ ln ⁡ π θ ( A t ∣ S t ) {\displaystyle \nabla _{\theta }\ln \pi _{\theta }(A_{t}\mid S_{t})} can be interpreted as the direction in the parameter space that increases the probability of taking action A t {\displaystyle A_{t}} in state S t {\displaystyle S_{t}} . The policy gradient, then, is a weighted average of all possible directions to increase the probability of taking any action in any state, but weighted by reward signals, so that if taking a certain action in a certain state is associated with high reward, then that direction would be highly reinforced, and vice versa. === Algorithm === The REINFORCE algorithm is a loop: Rollout N {\displaystyle N} trajectories in the environment, using π θ t {\displaystyle \pi _{\theta _{t}}} as the policy function. Compute the policy gradient estimation: g i ← 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ t ln ⁡ π θ ( A t , n ∣ S t , n ) ∑ τ = t T ( γ τ R τ , n ) ] {\displaystyle g_{i}\leftarrow {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta _{t}}\ln \pi _{\theta }(A_{t,n}\mid S_{t,n})\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau ,n})\right]} Update the policy by gradient ascent: θ i + 1 ← θ i + α i g i {\displaystyle \theta _{i+1}\leftarrow \theta _{i}+\alpha _{i}g_{i}} Here, α i {\displaystyle \alpha _{i}} is the learning rate at update step i {\displaystyle i} . == Variance reduction == REINFORCE is an on-policy algorithm, meaning that the trajectories used for the update must be sampled from the current policy π θ {\displaystyle \pi _{\theta }} . This can lead to high variance in the updates, as the returns R ( τ ) {\displaystyle R(\tau )} can vary significantly between trajectories. Many variants of REINFORCE have been introduced, under the title of variance reduction. === REINFORCE with baseline === A common way for reducing variance is the REINFORCE with baseline algorithm, based on the following identity: ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t | S t ) ( ∑ τ = t T ( γ τ R τ ) − b ( S t ) ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })-b(S_{t})\right){\Big |}S_{0}=s_{0}\right]} for any function b : States → R {\displaystyle b:{\text{States}}\to \mathbb {R} } . This can be proven by applying the previous lemma. The algorithm uses the modified gradient estimator g i ← 1 N ∑ n = 1 N [ ∑ t = 0 T ∇ θ t ln ⁡ π θ ( A t , n | S t , n ) ( ∑ τ = t T ( γ τ R τ , n ) − b i ( S t , n ) ) ] {\displaystyle g_{i}\leftarrow {\frac {1}{N}}\sum _{n=1}^{N}\left[\sum _{t=0}^{T}\nabla _{\theta _{t}}\ln \pi _{\theta }(A_{t,n}|S_{t,n})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau ,n})-b_{i}(S_{t,n})\right)\right]} and the original REINFORCE algorithm is the special case where b i ≡ 0 {\displaystyle b_{i}\equiv 0} . === Actor-critic methods === If b i {\textstyle b_{i}} is chosen well, such that b i ( S t ) ≈ ∑ τ = t T ( γ τ R τ ) = γ t V π θ i ( S t ) {\textstyle b_{i}(S_{t})\approx \sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })=\gamma ^{t}V^{\pi _{\theta _{i}}}(S_{t})} , this could significantly decrease variance in the gradient estimation. That is, the baseline should be as close to the value function V π θ i ( S t ) {\displaystyle V^{\pi _{\theta _{i}}}(S_{t})} as possible, approaching the ideal of: ∇ θ J ( θ ) = E π θ [ ∑ t = 0 T ∇ θ ln ⁡ π θ ( A t | S t ) ( ∑ τ = t T ( γ τ R τ ) − γ t V π θ ( S t ) ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=\mathbb {E} _{\pi _{\theta }}\left[\sum _{t=0}^{T}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\left(\sum _{\tau =t}^{T}(\gamma ^{\tau }R_{\tau })-\gamma ^{t}V^{\pi _{\theta }}(S_{t})\right){\Big |}S_{0}=s_{0}\right]} Note that, as the policy π θ t {\displaystyle \pi _{\theta _{t}}} updates, the value function V π θ i ( S t ) {\displaystyle V^{\pi _{\theta _{i}}}(S_{t})} updates as well, so the baseline should also be updated. One common approach is to train a separate function that estimates the value function, and use that as the baseline. This is one of the actor-critic methods, where the policy function is the actor and the value function is the critic. The Q-function Q π {\displaystyle Q^{\pi }} can also be used as the critic, since ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T γ t ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ Q π θ ( S t , A t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\sum _{0\leq t\leq T}\gamma ^{t}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\cdot Q^{\pi _{\theta }}(S_{t},A_{t}){\Big |}S_{0}=s_{0}\right]} by a similar argument using the tower law. Subtracting the value function as a baseline, we find that the advantage function A π ( S , A ) = Q π ( S , A ) − V π ( S ) {\displaystyle A^{\pi }(S,A)=Q^{\pi }(S,A)-V^{\pi }(S)} can be used as the critic as well: ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T γ t ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ A π θ ( S t , A t ) | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\sum _{0\leq t\leq T}\gamma ^{t}\nabla _{\theta }\ln \pi _{\theta }(A_{t}|S_{t})\cdot A^{\pi _{\theta }}(S_{t},A_{t}){\Big |}S_{0}=s_{0}\right]} In summary, there are many unbiased estimators for ∇ θ J θ {\textstyle \nabla _{\theta }J_{\theta }} , all in the form of: ∇ θ J ( θ ) = E π θ [ ∑ 0 ≤ t ≤ T ∇ θ ln ⁡ π θ ( A t | S t ) ⋅ Ψ t | S 0 = s 0 ] {\displaystyle \nabla _{\theta }J(\theta )=E_{\pi _{\theta }}\left[\su

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  L-1 Identity Solutions

  L-1 Identity Solutions, Inc. was an American biometric technology company headquartered in Stamford, Connecticut, specializing in identity management products and services including facial recognition systems, fingerprint readers, and secure credentialing solutions for governments and commercial enterprises. The company's shares traded on the New York Stock Exchange under the ticker symbol "ID." == History == L-1 Identity Solutions was formed on August 29, 2006, from a merger of Viisage Technology, Inc. and Identix Incorporated. Prior to the Safran acquisition, L-1 divested its Intelligence Services Group (ISG) comprising SpecTal LLC, Advanced Concepts Inc., and McClendon LLC to BAE Systems, Inc. for approximately $297 million. The transaction, initially announced in September 2010, closed on February 15, 2011, with more than 1,000 ISG employees joining BAE Systems' Intelligence & Security sector. It specializes in selling face recognition systems, electronic passports, such as Fly Clear, and other biometric technology to governments such as the United States and Saudi Arabia. It also licenses technology to other companies internationally, including China. On July 26, 2011, Safran (NYSE Euronext Paris: SAF) acquired L-1 Identity Solutions, Inc. for a total cash amount of USD 1.09 billion. L-1 was part of Morpho's MorphoTrust department which rebranded to Idemia in 2017. Bioscrypt is a biometrics research, development and manufacturing company purchased by L-1 Identity Solutions. It provides fingerprint IP readers for physical access control systems, Facial recognition system readers for contactless access control authentication and OEM fingerprint modules for embedded applications. According to IMS Research, Bioscrypt has been the world market leader in biometric access control for enterprises (since 2006) with a worldwide market share of over 13%. In 2011, Bioscrypt was sold to Safran Morpho.

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  Line integral convolution

  In scientific visualization, line integral convolution (LIC) is a method to visualize a vector field (such as fluid motion) at high spatial resolutions. The LIC technique was first proposed by Brian Cabral and Leith Casey Leedom in 1993. In LIC, discrete numerical line integration is performed along the field lines (curves) of the vector field on a uniform grid. The integral operation is a convolution of a filter kernel and an input texture, often white noise. In signal processing, this process is known as a discrete convolution. == Overview == Traditional visualizations of vector fields use small arrows or lines to represent vector direction and magnitude. This method has a low spatial resolution, which limits the density of presentable data and risks obscuring characteristic features in the data. More sophisticated methods, such as streamlines and particle tracing techniques, can be more revealing but are highly dependent on proper seed points. Texture-based methods, like LIC, avoid these problems since they depict the entire vector field at point-like (pixel) resolution. Compared to other integration-based techniques that compute field lines of the input vector field, LIC has the advantage that all structural features of the vector field are displayed, without the need to adapt the start and end points of field lines to the specific vector field. In other words, it shows the topology of the vector field. In user testing, LIC was found to be particularly good for identifying critical points. == Algorithm == === Informal description === LIC causes output values to be strongly correlated along the field lines, but uncorrelated in orthogonal directions. As a result, the field lines contrast each other and stand out visually from the background. Intuitively, the process can be understood with the following example: the flow of a vector field can be visualized by overlaying a fixed, random pattern of dark and light paint. As the flow passes by the paint, the fluid picks up some of the paint's color, averaging it with the color it has already acquired. The result is a randomly striped, smeared texture where points along the same streamline tend to have a similar color. Other physical examples include: whorl patterns of paint, oil, or foam on a river visualisation of magnetic field lines using randomly distributed iron filings fine sand being blown by strong wind === Formal mathematical description === Although the input vector field and the result image are discretized, it pays to look at it from a continuous viewpoint. Let v {\displaystyle \mathbf {v} } be the vector field given in some domain Ω {\displaystyle \Omega } . Although the input vector field is typically discretized, we regard the field v {\displaystyle \mathbf {v} } as defined in every point of Ω {\displaystyle \Omega } , i.e. we assume an interpolation. Streamlines, or more generally field lines, are tangent to the vector field in each point. They end either at the boundary of Ω {\displaystyle \Omega } or at critical points where v = 0 {\displaystyle \mathbf {v} =\mathbf {0} } . For the sake of simplicity, critical points and boundaries are ignored in the following. A field line σ {\displaystyle {\boldsymbol {\sigma }}} , parametrized by arc length s {\displaystyle s} , is defined as d σ ( s ) d s = v ( σ ( s ) ) | v ( σ ( s ) ) | . {\displaystyle {\frac {d{\boldsymbol {\sigma }}(s)}{ds}}={\frac {\mathbf {v} ({\boldsymbol {\sigma }}(s))}{|\mathbf {v} ({\boldsymbol {\sigma }}(s))|}}.} Let σ r ( s ) {\displaystyle {\boldsymbol {\sigma }}_{\mathbf {r} }(s)} be the field line that passes through the point r {\displaystyle \mathbf {r} } for s = 0 {\displaystyle s=0} . Then the image gray value at r {\displaystyle \mathbf {r} } is set to D ( r ) = ∫ − L / 2 L / 2 k ( s ) N ( σ r ( s ) ) d s {\displaystyle D(\mathbf {r} )=\int _{-L/2}^{L/2}k(s)N({\boldsymbol {\sigma }}_{\mathbf {r} }(s))ds} where k ( s ) {\displaystyle k(s)} is the convolution kernel, N ( r ) {\displaystyle N(\mathbf {r} )} is the noise image, and L {\displaystyle L} is the length of field line segment that is followed. D ( r ) {\displaystyle D(\mathbf {r} )} has to be computed for each pixel in the LIC image. If carried out naively, this is quite expensive. First, the field lines have to be computed using a numerical method for solving ordinary differential equations, like a Runge–Kutta method, and then for each pixel the convolution along a field line segment has to be calculated. The final image will normally be colored in some way. Typically, some scalar field in Ω {\displaystyle \Omega } (like the vector length) is used to determine the hue, while the grayscale LIC output determines the brightness. Different choices of convolution kernels and random noise produce different textures; for example, pink noise produces a cloudy pattern where areas of higher flow stand out as smearing, suitable for weather visualization. Further refinements in the convolution can improve the quality of the image. === Programming description === Algorithmically, LIC takes a vector field and noise texture as input, and outputs a texture. The process starts by generating in the domain of the vector field a random gray level image at the desired output resolution. Then, for every pixel in this image, the forward and backward streamline of a fixed arc length is calculated. The value assigned to the current pixel is computed by a convolution of a suitable convolution kernel with the gray levels of all the noise pixels lying on a segment of this streamline. This creates a gray level LIC image. == Versions == === Basic === Basic LIC images are grayscale images, without color and animation. While such LIC images convey the direction of the field vectors, they do not indicate orientation; for stationary fields, this can be remedied by animation. Basic LIC images do not show the length of the vectors (or the strength of the field). === Color === The length of the vectors (or the strength of the field) is usually coded in color; alternatively, animation can be used. === Animation === LIC images can be animated by using a kernel that changes over time. Samples at a constant time from the streamline would still be used, but instead of averaging all pixels in a streamline with a static kernel, a ripple-like kernel constructed from a periodic function multiplied by a Hann function acting as a window (in order to prevent artifacts) is used. The periodic function is then shifted along the period to create an animation. === Fast LIC (FLIC) === The computation can be significantly accelerated by re-using parts of already computed field lines, specializing to a box function as convolution kernel k ( s ) {\displaystyle k(s)} and avoiding redundant computations during convolution. The resulting fast LIC method can be generalized to convolution kernels that are arbitrary polynomials. === Oriented Line Integral Convolution (OLIC) === Because LIC does not encode flow orientation, it cannot distinguish between streamlines of equal direction but opposite orientation. Oriented Line Integral Convolution (OLIC) solves this issue by using a ramp-like asymmetric kernel and a low-density noise texture. The kernel asymmetrically modulates the intensity along the streamline, producing a trace that encodes orientation; the low-density of the noise texture prevents smeared traces from overlapping, aiding readability. Fast Rendering of Oriented Line Integral Convolution (FROLIC) is a variation that approximates OLIC by rendering each trace in discrete steps instead of as a continuous smear. === Unsteady Flow LIC (UFLIC) === For time-dependent vector fields (unsteady flow), a variant called Unsteady Flow LIC has been designed that maintains the coherence of the flow animation. An interactive GPU-based implementation of UFLIC has been presented. === Parallel === Since the computation of an LIC image is expensive but inherently parallel, the process has been parallelized and, with availability of GPU-based implementations, interactive on PCs. === Multidimensional === Note that the domain Ω {\displaystyle \Omega } does not have to be a 2D domain: the method is applicable to higher dimensional domains using multidimensional noise fields. However, the visualization of the higher-dimensional LIC texture is problematic; one way is to use interactive exploration with 2D slices that are manually positioned and rotated. The domain Ω {\displaystyle \Omega } does not have to be flat either; the LIC texture can be computed also for arbitrarily shaped 2D surfaces in 3D space. == Applications == This technique has been applied to a wide range of problems since it first was published in 1993, both scientific and creative, including: Representing vector fields: visualization of steady (time-independent) flows (streamlines) visual exploration of 2D autonomous dynamical systems wind mapping water flow mapping Artistic effects for image generation and stylization: pencil drawing (auto

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  Promoter based genetic algorithm

  The promoter based genetic algorithm (PBGA) is a genetic algorithm for neuroevolution developed by F. Bellas and R.J. Duro in the Integrated Group for Engineering Research (GII) at the University of Coruña, in Spain. It evolves variable size feedforward artificial neural networks (ANN) that are encoded into sequences of genes for constructing a basic ANN unit. Each of these blocks is preceded by a gene promoter acting as an on/off switch that determines if that particular unit will be expressed or not. == PBGA basics == The basic unit in the PBGA is a neuron with all of its inbound connections as represented in the following figure: The genotype of a basic unit is a set of real valued weights followed by the parameters of the neuron and proceeded by an integer valued field that determines the promoter gene value and, consequently, the expression of the unit. By concatenating units of this type we can construct the whole network. With this encoding it is imposed that the information that is not expressed is still carried by the genotype in evolution but it is shielded from direct selective pressure, maintaining this way the diversity in the population, which has been a design premise for this algorithm. Therefore, a clear difference is established between the search space and the solution space, permitting information learned and encoded into the genotypic representation to be preserved by disabling promoter genes. == Results == The PBGA was originally presented within the field of autonomous robotics, in particular in the real time learning of environment models of the robot. It has been used inside the Multilevel Darwinist Brain (MDB) cognitive mechanism developed in the GII for real robots on-line learning. In another paper it is shown how the application of the PBGA together with an external memory that stores the successful obtained world models, is an optimal strategy for adaptation in dynamic environments. Recently, the PBGA has provided results that outperform other neuroevolutionary algorithms in non-stationary problems, where the fitness function varies in time.

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  Farthest-first traversal

  In computational geometry, the farthest-first traversal of a compact metric space is a sequence of points in the space, where the first point is selected arbitrarily and each successive point is as far as possible from the set of previously-selected points. The same concept can also be applied to a finite set of geometric points, by restricting the selected points to belong to the set or equivalently by considering the finite metric space generated by these points. For a finite metric space or finite set of geometric points, the resulting sequence forms a permutation of the points, also known as the greedy permutation. Every prefix of a farthest-first traversal provides a set of points that is widely spaced and close to all remaining points. More precisely, no other set of equally many points can be spaced more than twice as widely, and no other set of equally many points can be less than half as far to its farthest remaining point. In part because of these properties, farthest-point traversals have many applications, including the approximation of the traveling salesman problem and the metric k-center problem. They may be constructed in polynomial time, or (for low-dimensional Euclidean spaces) approximated in near-linear time. == Definition and properties == A farthest-first traversal is a sequence of points in a compact metric space, with each point appearing at most once. If the space is finite, each point appears exactly once, and the traversal is a permutation of all of the points in the space. The first point of the sequence may be any point in the space. Each point p after the first must have the maximum possible distance to the set of points earlier than p in the sequence, where the distance from a point to a set is defined as the minimum of the pairwise distances to points in the set. A given space may have many different farthest-first traversals, depending both on the choice of the first point in the sequence (which may be any point in the space) and on ties for the maximum distance among later choices. Farthest-point traversals may be characterized by the following properties. Fix a number k, and consider the prefix formed by the first k points of the farthest-first traversal of any metric space. Let r be the distance between the final point of the prefix and the other points in the prefix. Then this subset has the following two properties: All pairs of the selected points are at distance at least r from each other, and All points of the metric space are at distance at most r from the subset. Conversely any sequence having these properties, for all choices of k, must be a farthest-first traversal. These are the two defining properties of a Delone set, so each prefix of the farthest-first traversal forms a Delone set. == Applications == Rosenkrantz, Stearns & Lewis (1977) used the farthest-first traversal to define the farthest-insertion heuristic for the travelling salesman problem. This heuristic finds approximate solutions to the travelling salesman problem by building up a tour on a subset of points, adding one point at a time to the tour in the ordering given by a farthest-first traversal. To add each point to the tour, one edge of the previous tour is broken and replaced by a pair of edges through the added point, in the cheapest possible way. Although Rosenkrantz et al. prove only a logarithmic approximation ratio for this method, they show that in practice it often works better than other insertion methods with better provable approximation ratios. Later, the same sequence of points was popularized by Gonzalez (1985), who used it as part of greedy approximation algorithms for two problems in clustering, in which the goal is to partition a set of points into k clusters. One of the two problems that Gonzalez solve in this way seeks to minimize the maximum diameter of a cluster, while the other, known as the metric k-center problem, seeks to minimize the maximum radius, the distance from a chosen central point of a cluster to the farthest point from it in the same cluster. For instance, the k-center problem can be used to model the placement of fire stations within a city, in order to ensure that every address within the city can be reached quickly by a fire truck. For both clustering problems, Gonzalez chooses a set of k cluster centers by selecting the first k points of a farthest-first traversal, and then creates clusters by assigning each input point to the nearest cluster center. If r is the distance from the set of k selected centers to the next point at position k + 1 in the traversal, then with this clustering every point is within distance r of its center and every cluster has diameter at most 2r. However, the subset of k centers together with the next point are all at distance at least r from each other, and any k-clustering would put some two of these points into a single cluster, with one of them at distance at least r/2 from its center and with diameter at least r. Thus, Gonzalez's heuristic gives an approximation ratio of 2 for both clustering problems. Gonzalez's heuristic was independently rediscovered for the metric k-center problem by Dyer & Frieze (1985), who applied it more generally to weighted k-center problems. Another paper on the k-center problem from the same time, Hochbaum & Shmoys (1985), achieves the same approximation ratio of 2, but its techniques are different. Nevertheless, Gonzalez's heuristic, and the name "farthest-first traversal", are often incorrectly attributed to Hochbaum and Shmoys. For both the min-max diameter clustering problem and the metric k-center problem, these approximations are optimal: the existence of a polynomial-time heuristic with any constant approximation ratio less than 2 would imply that P = NP. As well as for clustering, the farthest-first traversal can also be used in another type of facility location problem, the max-min facility dispersion problem, in which the goal is to choose the locations of k different facilities so that they are as far apart from each other as possible. More precisely, the goal in this problem is to choose k points from a given metric space or a given set of candidate points, in such a way as to maximize the minimum pairwise distance between the selected points. Again, this can be approximated by choosing the first k points of a farthest-first traversal. If r denotes the distance of the kth point from all previous points, then every point of the metric space or the candidate set is within distance r of the first k − 1 points. By the pigeonhole principle, some two points of the optimal solution (whatever it is) must both be within distance r of the same point among these first k − 1 chosen points, and (by the triangle inequality) within distance 2r of each other. Therefore, the heuristic solution given by the farthest-first traversal is within a factor of two of optimal. Other applications of the farthest-first traversal include color quantization (clustering the colors in an image to a smaller set of representative colors), progressive scanning of images (choosing an order to display the pixels of an image so that prefixes of the ordering produce good lower-resolution versions of the whole image rather than filling in the image from top to bottom), point selection in the probabilistic roadmap method for motion planning, simplification of point clouds, generating masks for halftone images, hierarchical clustering, finding the similarities between polygon meshes of similar surfaces, choosing diverse and high-value observation targets for underwater robot exploration, fault detection in sensor networks, modeling phylogenetic diversity, matching vehicles in a heterogenous fleet to customer delivery requests, uniform distribution of geodetic observatories on the Earth's surface or of other types of sensor network, generation of virtual point lights in the instant radiosity computer graphics rendering method, and geometric range searching data structures. == Algorithms == === Greedy exact algorithm === The farthest-first traversal of a finite point set may be computed by a greedy algorithm that maintains the distance of each point from the previously selected points, performing the following steps: Initialize the sequence of selected points to the empty sequence, and the distances of each point to the selected points to infinity. While not all points have been selected, repeat the following steps: Scan the list of not-yet-selected points to find a point p that has the maximum distance from the selected points. Remove p from the not-yet-selected points and add it to the end of the sequence of selected points. For each remaining not-yet-selected point q, replace the distance stored for q by the minimum of its old value and the distance from p to q. For a set of n points, this algorithm takes O(n2) steps and O(n2) distance computations. === Approximations === A faster approximation algorithm, given by Har-Peled & Mendel (2006), applie

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  Inductive logic programming

  Inductive logic programming (ILP) is a subfield of symbolic artificial intelligence which uses logic programming as a uniform representation for examples, background knowledge and hypotheses. The term "inductive" here refers to philosophical (i.e. suggesting a theory to explain observed facts) rather than mathematical (i.e. proving a property for all members of a well-ordered set) induction. Given an encoding of the known background knowledge and a set of examples represented as a logical database of facts, an ILP system will derive a hypothesised logic program which entails all the positive and none of the negative examples. Schema: positive examples + negative examples + background knowledge ⇒ hypothesis. Bioinformatics and drug design have been highlighted as a principal application area of inductive logic programming techniques. == History == Building on earlier work on Inductive inference, Gordon Plotkin was the first to formalise induction in a clausal setting around 1970, adopting an approach of generalising from examples. In 1981, Ehud Shapiro introduced several ideas that would shape the field in his new approach of model inference, an algorithm employing refinement and backtracing to search for a complete axiomatisation of given examples. His first implementation was the Model Inference System in 1981: a Prolog program that inductively inferred Horn clause logic programs from positive and negative examples. The term Inductive Logic Programming was first introduced in a paper by Stephen Muggleton in 1990, defined as the intersection of machine learning and logic programming. Muggleton and Wray Buntine introduced predicate invention and inverse resolution in 1988. Several inductive logic programming systems that proved influential appeared in the early 1990s. FOIL, introduced by Ross Quinlan in 1990 was based on upgrading propositional learning algorithms AQ and ID3. Golem, introduced by Muggleton and Feng in 1990, went back to a restricted form of Plotkin's least generalisation algorithm. The Progol system, introduced by Muggleton in 1995, first implemented inverse entailment, and inspired many later systems. Aleph, a descendant of Progol introduced by Ashwin Srinivasan in 2001, is still one of the most widely used systems as of 2022. At around the same time, the first practical applications emerged, particularly in bioinformatics, where by 2000 inductive logic programming had been successfully applied to drug design, carcinogenicity and mutagenicity prediction, and elucidation of the structure and function of proteins. Unlike the focus on automatic programming inherent in the early work, these fields used inductive logic programming techniques from a viewpoint of relational data mining. The success of those initial applications and the lack of progress in recovering larger traditional logic programs shaped the focus of the field. Recently, classical tasks from automated programming have moved back into focus, as the introduction of meta-interpretative learning makes predicate invention and learning recursive programs more feasible. This technique was pioneered with the Metagol system introduced by Muggleton, Dianhuan Lin, Niels Pahlavi and Alireza Tamaddoni-Nezhad in 2014. This allows ILP systems to work with fewer examples, and brought successes in learning string transformation programs, answer set grammars and general algorithms. == Setting == Inductive logic programming has adopted several different learning settings, the most common of which are learning from entailment and learning from interpretations. In both cases, the input is provided in the form of background knowledge B, a logical theory (commonly in the form of clauses used in logic programming), as well as positive and negative examples, denoted E + {\textstyle E^{+}} and E − {\textstyle E^{-}} respectively. The output is given as a hypothesis H, itself a logical theory that typically consists of one or more clauses. The two settings differ in the format of examples presented. === Learning from entailment === As of 2022, learning from entailment is by far the most popular setting for inductive logic programming. In this setting, the positive and negative examples are given as finite sets E + {\textstyle E^{+}} and E − {\textstyle E^{-}} of positive and negated ground literals, respectively. A correct hypothesis H is a set of clauses satisfying the following requirements, where the turnstile symbol ⊨ {\displaystyle \models } stands for logical entailment: Completeness: B ∪ H ⊨ E + Consistency: B ∪ H ∪ E − ⊭ false {\displaystyle {\begin{array}{llll}{\text{Completeness:}}&B\cup H&\models &E^{+}\\{\text{Consistency: }}&B\cup H\cup E^{-}&\not \models &{\textit {false}}\end{array}}} Completeness requires any generated hypothesis H to explain all positive examples E + {\textstyle E^{+}} , and consistency forbids generation of any hypothesis H that is inconsistent with the negative examples E − {\textstyle E^{-}} , both given the background knowledge B. In Muggleton's setting of concept learning, "completeness" is referred to as "sufficiency", and "consistency" as "strong consistency". Two further conditions are added: "Necessity", which postulates that B does not entail E + {\textstyle E^{+}} , does not impose a restriction on H, but forbids any generation of a hypothesis as long as the positive facts are explainable without it. "Weak consistency", which states that no contradiction can be derived from B ∧ H {\textstyle B\land H} , forbids generation of any hypothesis H that contradicts the background knowledge B. Weak consistency is implied by strong consistency; if no negative examples are given, both requirements coincide. Weak consistency is particularly important in the case of noisy data, where completeness and strong consistency cannot be guaranteed. === Learning from interpretations === In learning from interpretations, the positive and negative examples are given as a set of complete or partial Herbrand structures, each of which are themselves a finite set of ground literals. Such a structure e is said to be a model of the set of clauses B ∪ H {\textstyle B\cup H} if for any substitution θ {\textstyle \theta } and any clause h e a d ← b o d y {\textstyle \mathrm {head} \leftarrow \mathrm {body} } in B ∪ H {\textstyle B\cup H} such that b o d y θ ⊆ e {\textstyle \mathrm {body} \theta \subseteq e} , h e a d θ ⊆ e {\displaystyle \mathrm {head} \theta \subseteq e} also holds. The goal is then to output a hypothesis that is complete, meaning every positive example is a model of B ∪ H {\textstyle B\cup H} , and consistent, meaning that no negative example is a model of B ∪ H {\textstyle B\cup H} . == Approaches to ILP == An inductive logic programming system is a program that takes as an input logic theories B , E + , E − {\displaystyle B,E^{+},E^{-}} and outputs a correct hypothesis H with respect to theories B , E + , E − {\displaystyle B,E^{+},E^{-}} . A system is complete if and only if for any input logic theories B , E + , E − {\displaystyle B,E^{+},E^{-}} any correct hypothesis H with respect to these input theories can be found with its hypothesis search procedure. Inductive logic programming systems can be roughly divided into two classes, search-based and meta-interpretative systems. Search-based systems exploit that the space of possible clauses forms a complete lattice under the subsumption relation, where one clause C 1 {\textstyle C_{1}} subsumes another clause C 2 {\textstyle C_{2}} if there is a substitution θ {\textstyle \theta } such that C 1 θ {\textstyle C_{1}\theta } , the result of applying θ {\textstyle \theta } to C 1 {\textstyle C_{1}} , is a subset of C 2 {\textstyle C_{2}} . This lattice can be traversed either bottom-up or top-down. === Bottom-up search === Bottom-up methods to search the subsumption lattice have been investigated since Plotkin's first work on formalising induction in clausal logic in 1970. Techniques used include least general generalisation, based on anti-unification, and inverse resolution, based on inverting the resolution inference rule. ==== Least general generalisation ==== A least general generalisation algorithm takes as input two clauses C 1 {\textstyle C_{1}} and C 2 {\textstyle C_{2}} and outputs the least general generalisation of C 1 {\textstyle C_{1}} and C 2 {\textstyle C_{2}} , that is, a clause C {\textstyle C} that subsumes C 1 {\textstyle C_{1}} and C 2 {\textstyle C_{2}} , and that is subsumed by every other clause that subsumes C 1 {\textstyle C_{1}} and C 2 {\textstyle C_{2}} . The least general generalisation can be computed by first computing all selections from C 1 {\textstyle C_{1}} and C 2 {\textstyle C_{2}} , which are pairs of literals ( L , M ) ∈ ( C 1 × C 2 ) {\displaystyle (L,M)\in (C_{1}\times C_{2})} sharing the same predicate symbol and negated/unnegated status. Then, the least general generalisation is obtained as the disjunction of the least general generalisations of the indi

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  WebGPU Shading Language

  WebGPU Shading Language (WGSL, internet media type: text/wgsl) is a high-level shading language and the normative shader language for the WebGPU API on the web. WGSL's syntax is influenced by Rust and is designed with strong static validation, explicit resource binding, and portability in mind for secure execution in browsers. In web contexts, WebGPU implementations accept WGSL source and perform compilation to platform-specific intermediate forms (for example, to SPIR‑V, DXIL, or MSL via the user agent), but such backends are not exposed to web content. == History and background == Graphics on the web historically used WebGL, with shaders written in GLSL ES. As applications demanded more modern GPU features and finer control over compute and graphics pipelines, the W3C's GPU for the Web Community Group and Working Group created WebGPU and its companion shading language, WGSL, to provide a secure, portable model suitable for the web platform. WGSL was developed to be human-readable, avoid undefined behavior common in legacy shading languages, and align closely with WebGPU's resource and validation model. == Design goals == WGSL's design emphasizes: Safety and determinism suitable for web security constraints (extensive static validation and well-defined semantics). Portability across diverse GPU backends via an abstract resource model shared with WebGPU. Readability and explicitness (no preprocessor, minimal implicit conversions, explicit address spaces and bindings). Alignment with modern GPU features (compute, storage buffers, textures, atomics) while retaining a familiar C/Rust-like syntax. == Language overview == === Types and values === Core scalar types include bool, i32, u32, and f32. Vectors (e.g., vec2, vec3, vec4) and matrices (up to 4×4) are available for floating-point element types. Optional f16 (half precision) may be enabled via a WebGPU feature; availability is implementation-dependent. Atomic types (atomic, atomic) support limited atomic operations in qualified address spaces. === Variables and address spaces === Variables are declared with let (immutable), var (mutable), or const (compile-time constant). Storage classes (address spaces) include function, private, workgroup, uniform, and storage with read or read_write access as applicable. WGSL defines explicit layout and alignment rules; attributes such as @align, @size, and @stride control data layout for buffer interoperability. === Functions and control flow === Functions use explicit parameter and return types. Control flow includes if, switch, for, while, and loop constructs, with break/continue. Recursion is disallowed; entry-point call graphs must be acyclic. === Entry points and attributes === Shaders define stage entry points with @vertex, @fragment, or @compute. Attributes annotate bindings and interfaces, including @group, @binding (resource binding), @location (user-defined I/O), @builtin (stage built-ins such as position or global_invocation_id), @interpolate, and @workgroup_size. === Resources === WGSL exposes buffers (uniform, storage), textures (sampled, storage, and multisampled variants), and samplers (filtering/non-filtering/comparison). The binding model is explicit via descriptor sets called groups and bindings, matching WebGPU's pipeline layout model. == Compilation and validation == Browsers compile WGSL to platform-appropriate representations and native driver formats; the specific compilation pipeline is not observable by web content. WGSL source undergoes strict parsing and static validation, and WebGPU enforces robust resource access rules to avoid out-of-bounds memory hazards, contributing to predictable behavior across implementations. == Shader stages == WGSL supports three pipeline stages: vertex, fragment, and compute. === Vertex shaders === Vertex shaders transform per-vertex inputs and produce values for rasterization, including a clip-space position written to the position builtin. ==== Example ==== === Fragment shaders === Fragment shaders run per-fragment and compute color (and optionally depth) outputs written to color attachments. ==== Example ==== If half-precision (vec4h, shorthand for vec4) is desired, the code must be prefaced with a enable f16; statement. === Compute shaders === Compute shaders run in workgroups and are used for general-purpose GPU computations. ==== Example ==== == Differences from GLSL and HLSL == Compared with legacy shading languages, WGSL: Omits a preprocessor and requires explicit types and conversions. Uses explicit address spaces and binding annotations aligned with WebGPU's model. Enforces strict validation to avoid undefined behavior common in other shading languages. Defines a portable, web-focused feature set; 16-bit types and other features are opt-in and may depend on device capabilities.

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  Handwriting recognition

  Handwriting recognition (HWR), also known as handwritten text recognition (HTR), is the ability of a computer to receive and interpret intelligible handwritten input from sources such as paper documents, photographs, touch-screens and other devices. The image of the written text may be sensed "off line" from a piece of paper by optical scanning (optical character recognition) or intelligent word recognition. Alternatively, the movements of the pen tip may be sensed "on line", for example by a pen-based computer screen surface, a generally easier task as there are more clues available. A handwriting recognition system handles formatting, performs correct segmentation into characters, and finds the most possible words. == Offline recognition == Offline handwriting recognition involves the automatic conversion of text in an image into letter codes that are usable within computer and text-processing applications. The data obtained by this form is regarded as a static representation of handwriting. Offline handwriting recognition is comparatively difficult, as different people have different handwriting styles. And, as of today, OCR engines are primarily focused on machine printed text and ICR for hand "printed" (written in capital letters) text. === Traditional techniques === ==== Character extraction ==== Offline character recognition often involves scanning a form or document. This means the individual characters contained in the scanned image will need to be extracted. Tools exist that are capable of performing this step. However, there are several common imperfections in this step. The most common is when characters that are connected are returned as a single sub-image containing both characters. This causes a major problem in the recognition stage. Yet many algorithms are available that reduce the risk of connected characters. ==== Character recognition ==== After individual characters have been extracted, a recognition engine is used to identify the corresponding computer character. Several different recognition techniques are currently available. ===== Feature extraction ===== Feature extraction works in a similar fashion to neural network recognizers. However, programmers must manually determine the properties they feel are important. This approach gives the recognizer more control over the properties used in identification. Yet any system using this approach requires substantially more development time than a neural network because the properties are not learned automatically. === Modern techniques === Where traditional techniques focus on segmenting individual characters for recognition, modern techniques focus on recognizing all the characters in a segmented line of text. Particularly they focus on machine learning techniques that are able to learn visual features, avoiding the limiting feature engineering previously used. State-of-the-art methods use convolutional networks to extract visual features over several overlapping windows of a text line image which a recurrent neural network uses to produce character probabilities. == Online recognition == Online handwriting recognition involves the automatic conversion of text as it is written on a special digitizer or PDA, where a sensor picks up the pen-tip movements as well as pen-up/pen-down switching. This kind of data is known as digital ink and can be regarded as a digital representation of handwriting. The obtained signal is converted into letter codes that are usable within computer and text-processing applications. The elements of an online handwriting recognition interface typically include: a pen or stylus for the user to write with a touch sensitive surface, which may be integrated with, or adjacent to, an output display. a software application which interprets the movements of the stylus across the writing surface, translating the resulting strokes into digital text. The process of online handwriting recognition can be broken down into a few general steps: preprocessing, feature extraction and classification The purpose of preprocessing is to discard irrelevant information in the input data, that can negatively affect the recognition. This concerns speed and accuracy. Preprocessing usually consists of binarization, normalization, sampling, smoothing and denoising. The second step is feature extraction. Out of the two- or higher-dimensional vector field received from the preprocessing algorithms, higher-dimensional data is extracted. The purpose of this step is to highlight important information for the recognition model. This data may include information like pen pressure, velocity or the changes of writing direction. The last big step is classification. In this step, various models are used to map the extracted features to different classes and thus identifying the characters or words the features represent. === Hardware === Commercial products incorporating handwriting recognition as a replacement for keyboard input were introduced in the early 1980s. Examples include handwriting terminals such as the Pencept Penpad and the Inforite point-of-sale terminal. With the advent of the large consumer market for personal computers, several commercial products were introduced to replace the keyboard and mouse on a personal computer with a single pointing/handwriting system, such as those from Pencept, CIC and others. The first commercially available tablet-type portable computer was the Write-Top from Linus Technologies, released in July 1988. Its operating system was based on MS-DOS. In the early 1990s, hardware makers including NCR, IBM and EO released tablet computers running the PenPoint operating system developed by GO Corp. PenPoint used handwriting recognition and gestures throughout and provided the facilities to third-party software. IBM's tablet computer was the first to use the ThinkPad name and used IBM's handwriting recognition. This recognition system was later ported to Microsoft Windows for Pen Computing, and IBM's Pen for OS/2. None of these were commercially successful. Advancements in electronics allowed the computing power necessary for handwriting recognition to fit into a smaller form factor than tablet computers, and handwriting recognition is often used as an input method for hand-held PDAs. The first PDA to provide written input was the Apple Newton, which exposed the public to the advantage of a streamlined user interface. However, the device was not a commercial success, owing to the unreliability of the software, which tried to learn a user's writing patterns. By the time of the release of the Newton OS 2.0, wherein the handwriting recognition was greatly improved, including unique features still not found in current recognition systems such as modeless error correction, the largely negative first impression had been made. After discontinuation of Apple Newton, the feature was incorporated in Mac OS X 10.2 and later as Inkwell. Palm later launched a successful series of PDAs based on the Graffiti recognition system. Graffiti improved usability by defining a set of "unistrokes", or one-stroke forms, for each character. This narrowed the possibility for erroneous input, although memorization of the stroke patterns did increase the learning curve for the user. The Graffiti handwriting recognition was found to infringe on a patent held by Xerox, and Palm replaced Graffiti with a licensed version of the CIC handwriting recognition which, while also supporting unistroke forms, pre-dated the Xerox patent. The court finding of infringement was reversed on appeal, and then reversed again on a later appeal. The parties involved subsequently negotiated a settlement concerning this and other patents. A Tablet PC is a notebook computer with a digitizer tablet and a stylus, which allows a user to handwrite text on the unit's screen. The operating system recognizes the handwriting and converts it into text. Windows Vista and Windows 7 include personalization features that learn a user's writing patterns or vocabulary for English, Japanese, Chinese Traditional, Chinese Simplified and Korean. The features include a "personalization wizard" that prompts for samples of a user's handwriting and uses them to retrain the system for higher accuracy recognition. This system is distinct from the less advanced handwriting recognition system employed in its Windows Mobile OS for PDAs. Although handwriting recognition is an input form that the public has become accustomed to, it has not achieved widespread use in either desktop computers or laptops. It is still generally accepted that keyboard input is both faster and more reliable. As of 2006, many PDAs offer handwriting input, sometimes even accepting natural cursive handwriting, but accuracy is still a problem, and some people still find even a simple on-screen keyboard more efficient. === Software === Early software could understand print handwriting where the characters were separated; however, cursive handwriting

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  Constructing skill trees

  Constructing skill trees (CST) is a hierarchical reinforcement learning algorithm which can build skill trees from a set of sample solution trajectories obtained from demonstration. CST uses an incremental MAP (maximum a posteriori) change point detection algorithm to segment each demonstration trajectory into skills and integrate the results into a skill tree. CST was introduced by George Konidaris, Scott Kuindersma, Andrew Barto and Roderic Grupen in 2010. == Algorithm == CST consists of mainly three parts;change point detection, alignment and merging. The main focus of CST is online change-point detection. The change-point detection algorithm is used to segment data into skills and uses the sum of discounted reward R t {\displaystyle R_{t}} as the target regression variable. Each skill is assigned an appropriate abstraction. A particle filter is used to control the computational complexity of CST. The change point detection algorithm is implemented as follows. The data for times t ∈ T {\displaystyle t\in T} and models Q with prior p ( q ∈ Q ) {\displaystyle p(q\in Q)} are given. The algorithm is assumed to be able to fit a segment from time j + 1 {\displaystyle j+1} to t using model q with the fit probability P ( j , t , q ) {\displaystyle P(j,t,q)_{}^{}} . A linear regression model with Gaussian noise is used to compute P ( j , t , q ) {\displaystyle P(j,t,q)} . The Gaussian noise prior has mean zero, and variance which follows I n v e r s e G a m m a ( v 2 , u 2 ) {\displaystyle \mathrm {InverseGamma} \left({\frac {v}{2}},{\frac {u}{2}}\right)} . The prior for each weight follows N o r m a l ( 0 , σ 2 δ ) {\displaystyle \mathrm {Normal} (0,\sigma ^{2}\delta )} . The fit probability P ( j , t , q ) {\displaystyle P(j,t,q)} is computed by the following equation. P ( j , t , q ) = π − n 2 δ m | ( A + D ) − 1 | 1 2 u v 2 ( y + u ) u + v 2 Γ ( n + v 2 ) Γ ( v 2 ) {\displaystyle P(j,t,q)={\frac {\pi ^{-{\frac {n}{2}}}}{\delta ^{m}}}\left|(A+D)^{-1}\right|^{\frac {1}{2}}{\frac {u^{\frac {v}{2}}}{(y+u)^{\frac {u+v}{2}}}}{\frac {\Gamma ({\frac {n+v}{2}})}{\Gamma ({\frac {v}{2}})}}} Then, CST compute the probability of the changepoint at time j with model q, P t ( j , q ) {\displaystyle P_{t}(j,q)} and P j MAP {\displaystyle P_{j}^{\text{MAP}}} using a Viterbi algorithm. P t ( j , q ) = ( 1 − G ( t − j − 1 ) ) P ( j , t , q ) p ( q ) P j MAP {\displaystyle P_{t}(j,q)=(1-G(t-j-1))P(j,t,q)p(q)P_{j}^{\text{MAP}}} P j MAP = max i , q P j ( i , q ) g ( j − i ) 1 − G ( j − i − 1 ) , ∀ j < t {\displaystyle P_{j}^{\text{MAP}}=\max _{i,q}{\frac {P_{j}(i,q)g(j-i)}{1-G(j-i-1)}},\forall j Read more →

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  Spiking neural network

  Spiking neural networks (SNNs) are artificial neural networks (ANN) that mimic natural neural networks. These models leverage timing of discrete spikes as the main information carrier. In addition to neuronal and synaptic state, SNNs incorporate the concept of time into their operating model. The idea is that neurons in the SNN do not transmit information at each propagation cycle (as it happens with typical multi-layer perceptron networks), but rather transmit information only when a membrane potential—an intrinsic quality of the neuron related to its membrane electrical charge—reaches a specific value, called the threshold. When the membrane potential reaches the threshold, the neuron fires, and generates a signal that travels to other neurons which, in turn, increase or decrease their potentials in response to this signal. A neuron model that fires at the moment of threshold crossing is also called a spiking neuron model. While spike rates can be considered the analogue of the variable output of a traditional ANN, neurobiology research indicated that high speed processing cannot be performed solely through a rate-based scheme. For example humans can perform an image recognition task requiring no more than 10ms of processing time per neuron through the successive layers (going from the retina to the temporal lobe). This time window is too short for rate-based encoding. The precise spike timings in a small set of spiking neurons also has a higher information coding capacity compared with a rate-based approach. The most prominent spiking neuron model is the leaky integrate-and-fire model. In that model, the momentary activation level (modeled as a differential equation) is normally considered to be the neuron's state, with incoming spikes pushing this value higher or lower, until the state eventually either decays or—if the firing threshold is reached—the neuron fires. After firing, the state variable is reset to a lower value. Various decoding methods exist for interpreting the outgoing spike train as a real-value number, relying on either the frequency of spikes (rate-code), the time-to-first-spike after stimulation, or the interval between spikes. == History == Many multi-layer artificial neural networks are fully connected, receiving input from every neuron in the previous layer and signalling every neuron in the subsequent layer. Although these networks have achieved breakthroughs, they do not match biological networks and do not mimic neurons. The biology-inspired Hodgkin–Huxley model of a spiking neuron was proposed in 1952. This model described how action potentials are initiated and propagated. Communication between neurons, which requires the exchange of chemical neurotransmitters in the synaptic gap, is described in models such as the integrate-and-fire model, FitzHugh–Nagumo model (1961–1962), and Hindmarsh–Rose model (1984). The leaky integrate-and-fire model (or a derivative) is commonly used as it is easier to compute than Hodgkin–Huxley. While the notion of an artificial spiking neural network became popular only in the twenty-first century, studies between 1980 and 1995 supported the concept. The first models of this type of ANN appeared to simulate non-algorithmic intelligent information processing systems. However, the notion of the spiking neural network as a mathematical model was first worked on in the early 1970s. As of 2019 SNNs lagged behind ANNs in accuracy, but the gap is decreasing, and has vanished on some tasks. == Underpinnings == Information in the brain is represented as action potentials (neuron spikes), which may group into spike trains or coordinated waves. A fundamental question of neuroscience is to determine whether neurons communicate by a rate or temporal code. Temporal coding implies that a single spiking neuron can replace hundreds of hidden units on a conventional neural net. SNNs define a neuron's current state as its potential (possibly modeled as a differential equation). An input pulse causes the potential to rise and then gradually decline. Encoding schemes can interpret these pulse sequences as a number, considering pulse frequency and pulse interval. Using the precise time of pulse occurrence, a neural network can consider more information and offer better computing properties. SNNs compute in the continuous domain. Such neurons test for activation only when their potentials reach a certain value. When a neuron is activated, it produces a signal that is passed to connected neurons, accordingly raising or lowering their potentials. The SNN approach produces a continuous output instead of the binary output of traditional ANNs. Pulse trains are not easily interpretable, hence the need for encoding schemes. However, a pulse train representation may be more suited for processing spatiotemporal data (or real-world sensory data classification). SNNs connect neurons only to nearby neurons so that they process input blocks separately (similar to CNN using filters). They consider time by encoding information as pulse trains so as not to lose information. This avoids the complexity of a recurrent neural network (RNN). Impulse neurons are more powerful computational units than traditional artificial neurons. SNNs are theoretically more powerful than so called "second-generation networks" defined as ANNs "based on computational units that apply activation function with a continuous set of possible output values to a weighted sum (or polynomial) of the inputs"; however, SNN training issues and hardware requirements limit their use. Although unsupervised biologically inspired learning methods are available such as Hebbian learning and STDP, no effective supervised training method is suitable for SNNs that can provide better performance than second-generation networks. Spike-based activation of SNNs is not differentiable, thus gradient descent-based backpropagation (BP) is not available. SNNs have much larger computational costs for simulating realistic neural models than traditional ANNs. Pulse-coupled neural networks (PCNN) are often confused with SNNs. A PCNN can be seen as a kind of SNN. Researchers are actively working on various topics. The first concerns differentiability. The expressions for both the forward- and backward-learning methods contain the derivative of the neural activation function which is not differentiable because a neuron's output is either 1 when it spikes, and 0 otherwise. This all-or-nothing behavior disrupts gradients and makes these neurons unsuitable for gradient-based optimization. Approaches to resolving it include: resorting to entirely biologically inspired local learning rules for the hidden units translating conventionally trained "rate-based" NNs to SNNs smoothing the network model to be continuously differentiable defining an SG (Surrogate Gradient) as a continuous relaxation of the real gradients The second concerns the optimization algorithm. Standard BP can be expensive in terms of computation, memory, and communication and may be poorly suited to the hardware that implements it (e.g., a computer, brain, or neuromorphic device). Incorporating additional neuron dynamics such as Spike Frequency Adaptation (SFA) is a notable advance, enhancing efficiency and computational power. These neurons sit between biological complexity and computational complexity. Originating from biological insights, SFA offers significant computational benefits by reducing power usage, especially in cases of repetitive or intense stimuli. This adaptation improves signal/noise clarity and introduces an elementary short-term memory at the neuron level, which in turn, improves accuracy and efficiency. This was mostly achieved using compartmental neuron models. The simpler versions are of neuron models with adaptive thresholds, are an indirect way of achieving SFA. It equips SNNs with improved learning capabilities, even with constrained synaptic plasticity, and elevates computational efficiency. This feature lessens the demand on network layers by decreasing the need for spike processing, thus lowering computational load and memory access time—essential aspects of neural computation. Moreover, SNNs utilizing neurons capable of SFA achieve levels of accuracy that rival those of conventional ANNs, while also requiring fewer neurons for comparable tasks. This efficiency streamlines the computational workflow and conserves space and energy, while maintaining technical integrity. High-performance deep spiking neural networks can operate with 0.3 spikes per neuron. == Applications == SNNs can in principle be applied to the same applications as traditional ANNs. In addition, SNNs can model the central nervous system of biological organisms, such as an insect seeking food without prior knowledge of the environment. Due to their relative realism, they can be used to study biological neural circuits. Starting with a hypothesis about the topology of a biological neuronal circuit and its functi

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  Artificial reproduction

  Artificial reproduction is the re-creation of life brought about by means other than natural ones. It is new life built by human plans and projects. Examples include artificial selection, artificial insemination, in vitro fertilization, artificial womb, artificial cloning, and kinematic replication. Artificial reproduction is one aspect of artificial life. Artificial reproduction can be categorized into one of two classes according to its capacity to be self-sufficient: non-assisted reproductive technology and assisted reproductive technology. Cutting plants' stems and placing them in compost is a form of assisted artificial reproduction, xenobots are an example of a more autonomous type of reproduction, while the artificial womb presented in the movie the Matrix illustrates a non assisted hypothetical technology. The idea of artificial reproduction has led to various technologies. == Theology == Humans have aspired to create life since immemorial times. Most theologies and religions have conceived this possibility as exclusive of deities. Christian religions consider the possibility of artificial reproduction, in most cases, as heretical and sinful. == Philosophy == Although ancient Greek philosophy raised the concept that man could imitate the creative capacity of nature, classic Greeks thought that if possible, human beings would reproduce things as nature does, and vice versa, nature would do the things that man does in the same way. Aristotle, for example, wrote that if nature made tables, it would make them just as men do. In other words, Aristotle said that if nature were to create a table, such table will look like a human-made table. Correspondingly, Descartes envisioned the human body, and nature, as a machine. Cartesian philosophy does not stop seeing a perfect mirror between nature and the artificial. However, Kant revolutionized this old idea by criticizing such naturalism. Kant pedagogically wrote: "Reason, in order to be taught by nature, must approach nature with its principles in one hand, according to which the agreement among appearances can count as laws, and, in the other hand, the experiment thought out in accord with these principles—in order to be instructed by nature not like a pupil, who has recited to him whatever the teacher wants to say, but like an appointed judge who compels witnesses to answer the questions he puts to them.". Humans are not instructed by nature but rather use nature as raw material to invent. Humans find alternatives to the natural restrictions imposed by natural laws thus, nature is not necessarily mirrored. In accordance with Kant (and contrary to what Aristotle thought) Karl Marx, Alfred Whitehead, Jaques Derrida and Juan David García Bacca noticed that nature is incapable of reproducing tables; or airplanes, or submarines, or computers. If nature tried to create airplanes, it would produce birds. If nature tried to create submarines, it would get fishes. If nature tried to create computers, brains would grow. And if nature tried to create man, modern man, monkeys will be evolved. According to Whitehead, if we look for something natural in artificial life, in the most elaborate cases, if anything, only atoms remain natural. Juan David Garcia Bacca summarized, “It will not come out from wood, it will not be born, a galley; from clay, a vessel; from linen, a dress; from iron, a lever,...From natural, artificial. In the artificial, the natural is reduced to a simple raw material, even though it is perfectly specified with natural specification. The artificial is the real, positive, and original negation of the natural: of species, of genus and of essence. Thus, its ontology is superior to natural ontology. And for this very reason Marx did not attach any importance to Darwin, whose evolutionism is confined to the natural order: to changes, at most, from variety to variety, from species to species... natural. For the same reason, nature has no dialectics, even though continuous evolution and selection can occur. The dialectic cannot emerge from the natural, for deeper reasons than, using today's terms, from a bird, an airplane cannot emerge; from fish, a submarine; from ears, a telephone; from eyes, a television; from a brain, a digital computer; from feet, a car; from hands, an engine; from Euclid, Descartes; from Aristotle, Newton; from Plato, Marx.” According to García Bacca, the major difference between natural causes and artificial causes is that nature does not have plans and projects, while humans design things following plans and projects. In contrast, other influential authors such as Michael Behe have depicted the concept and promoted the idea of intelligent design, a notion that has aroused several doubts and heated controversies, as it reframe natural causes in accordance with a natural plan. Previous ideas that have also provided a positive 'sense' to natural reproduction, are orthogenesis, syntropy, orgone and morphic resonance, among others. Although, these ideas have been historically marginalized and often called pseudoscience, recently Bio-semioticians are reconsidering some of them under symbolic approaches. Current metaphysics of science actually recognizes that the artificial ways of reproduction are diverse from nature, i.e., unnatural, anti-natural or supernatural. Because Biosemiotics does not focus on the function of life but on its meaning, it has a better understanding of the artificial than classic biology. == Science == Biology, being the study of cellular life, addresses reproduction in terms of growth and cellular division (i.e., binary fission, mitosis and meiosis); however, the science of artificial reproduction is not restricted by the mirroring of these natural processes.The science of artificial reproduction is actually transcending the natural forms, and natural rules, of reproduction. For example, xenobots have redefined the classical conception of reproduction. Although xenobots are made of eukariotic cells they do not reproduce by mitosis, but rather by kinematic replication. Such constructive replication does not involve growing but rather building. == Assisted reproductive technologies == Assisted reproductive technology (ART)'s purpose is to assist the development of a human embryo, commonly because of medical concerns due to fertility limitations. == Non-assisted reproductive technologies == Non-assisted reproductive technologies (NART) could have medical motivations but are mostly driven by a wider heterotopic ambition. Although, NARTs are initially designed by humans, they are programed to become independent of humans to a relative or absolute extent. James Lovelock proposed that such novelties could overcome humans. === Artificial cloning === Cloning is the cellular reproductive processes where two or more genetically identical organisms are created, either by natural or artificial means. Artificial cloning normally involves editing the genetic code, somatic cell nuclear transfer and 3D bioprinting. === Non-assisted artificial womb === A non-assisted artificial womb or artificial uterus is a device that allow for ectogenesis or extracorporeal pregnancy by growing an embryonic form outside the body of an organism (that would normally carry the embryo to term) without any human assistance. The aspect of non-assistance is the key distinction between the current artificial womb technology (AWT) in modern medical research, which still relies on human assistance. With this non-assisted hypothetical technology, a zygote or stem cells are used to create an embryo that is then incubated and monitored by artificial intelligence (AI) within a chamber composed of biocompatible material. The AI maintains the necessary conditions for the embryo to develop and thrive, proceeding to mimic organic labor and childbirth in order to best help the embryo adjust to the outside world. Ectogenesis—gestation, depicted in the science fiction movie The Matrix, is a fast approaching reality. This type of innovation presupposes that vertebrate wombs are not the only way for bearing humans or other similar forms of life. === Kinematic replication === Self-replication without binary fission, meiosis, mitosis (or any other form of cellular reproduction that involves division and growing) can be achieved. Xenobots are an example of kinematic replication. They are biobots, named after the African clawed frog (Xenopus laevis). Xenobots are cellular life forms designed by using artificial intelligence to build more of themselves by combining frog cells in a liquid medium. The term kinematic replication is usually reserved for biomolecules (e.g. DNA, RNA, prions, etc.) and artificially designed cellular forms (e.g. xenobots). === Machine constructive replication === Machine constructive replication mimics human traditional manufacturing but is entirely self-automated. Such constructive replication is a more general form of kinematic replication, which does not necessarily

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  Targeted maximum likelihood estimation

  Targeted Maximum Likelihood Estimation (TMLE) (also more accurately referred to as Targeted Minimum Loss-Based Estimation) is a general statistical estimation framework for causal inference and semiparametric models. TMLE combines ideas from maximum likelihood estimation, semiparametric efficiency theory, and machine learning. It was introduced by Mark J. van der Laan and colleagues in the mid-2000s as a method that yields asymptotically efficient plug-in estimators while allowing the use of flexible, data-adaptive algorithms such as ensemble machine learning for nuisance parameter estimation. TMLE is used in epidemiology, biostatistics, and the social sciences to estimate causal effects in observational and experimental studies. Applications of TMLE include Longitudinal TMLE (LTMLE) for time-varying treatments and confounders. Variations in how the targeting step in TMLE is carried out have resulted in various versions of TMLE such as Collaborative TMLE (CTMLE) and Adaptive TMLE for improved finite-sample performance and automated variable selection. == History == The TMLE framework was first described by van der Laan and Rubin (2006) as a general approach for the construction of efficient plug-in estimators of smooth features of the data density. It was demonstrated in the context of causal inference and missing data problems. It was developed to address limitations of traditional doubly robust methods, such as Augmented Inverse Probability Weighting (AIPW), by respecting the plug-in principle in the sense that it respects that the target parameter is a function of the data density that is an element of the statistical model. TMLE estimates the data density or relevant parts of it with machine learning and targets these machine learning fits before it is plugged in the target parameter mapping. In this manner, a TMLE always respects global knowledge and satisfies known bounds such as that the target parameter is a probability . Since its introduction, TMLE has been developed in a series of theoretical and applied papers, culminating in book-length treatments of the method and its applications to survival analysis, adaptive designs, and longitudinal data. == Methodology == At its core, TMLE is a two-step estimation procedure: Initial estimation: Machine learning methods (such as the Super Learner ensemble) are used to obtain flexible estimates of nuisance parameters, such as outcome regressions and propensity scores. Targeting step: The initial estimate is updated by solving a score equation (the efficient influence function) so that the final estimator is consistent, asymptotically normal, and efficient under mild regularity conditions. The targeted machine learning fit is then mapped into the corresponding estimator of the target parameter by simply plugging it in the target parameter mapping. This approach balances the bias–variance trade-off by combining data-adaptive estimation with semiparametric efficiency theory. TMLE is doubly robust, meaning it remains consistent if either the outcome model or the treatment model is consistently estimated. === Formula === Here we explain the TMLE of the average treatment effect of a binary treatment on an outcome adjusting for baseline covariates. Consider i.i.d. observations O i = ( W i , A i , Y i ) {\displaystyle O_{i}=(W_{i},A_{i},Y_{i})} from a distribution P 0 {\displaystyle P_{0}} , where W {\displaystyle W} are baseline covariates, A {\displaystyle A} is a binary treatment, and Y {\displaystyle Y} is an outcome. Let Q ¯ ( a , w ) = E [ Y ∣ A = a , W = w ] {\displaystyle {\bar {Q}}(a,w)=\mathbb {E} [Y\mid A=a,W=w]} represent the outcome model and g ( a ∣ w ) = P ( A = a ∣ W = w ) {\displaystyle g(a\mid w)=P(A=a\mid W=w)} represent the propensity score. The average treatment effect (ATE) is given by ψ 0 = E { Q ¯ ( 1 , W ) − Q ¯ ( 0 , W ) } . {\displaystyle \psi _{0}=\mathbb {E} \{{\bar {Q}}(1,W)-{\bar {Q}}(0,W)\}.} A basic TMLE for the ATE proceeds as follows: Step 1: Estimate initial models. Obtain estimates Q ¯ ^ ( a , w ) {\displaystyle {\hat {\bar {Q}}}(a,w)} and g ^ ( a ∣ w ) {\displaystyle {\hat {g}}(a\mid w)} , often using flexible methods such as Super Learner. Step 2: Compute the clever covariate. Define: H ( A , W ) = A g ^ ( 1 ∣ W ) − 1 − A g ^ ( 0 ∣ W ) . {\displaystyle H(A,W)={\frac {A}{{\hat {g}}(1\mid W)}}-{\frac {1-A}{{\hat {g}}(0\mid W)}}.} Step 3: Estimate the fluctuation parameter. Fit a logistic regression of Y {\displaystyle Y} on H ( A , W ) {\displaystyle H(A,W)} with logit ⁡ ( Q ¯ ^ ( A , W ) ) {\displaystyle \operatorname {logit} ({\hat {\bar {Q}}}(A,W))} as offset. This yields ε ^ {\displaystyle {\hat {\varepsilon }}} , the MLE that solves the score equation: 1 n ∑ i = 1 n H ( A i , W i ) { Y i − Q ¯ ^ ε ( A i , W i ) } = 0. {\displaystyle {\frac {1}{n}}\sum _{i=1}^{n}H(A_{i},W_{i}){\big \{}Y_{i}-{\hat {\bar {Q}}}^{\varepsilon }(A_{i},W_{i}){\big \}}=0.} Step 4: Update the initial estimate. Apply the "blip" to obtain the targeted estimate: Q ¯ ^ ∗ ( A , W ) = expit ⁡ ( logit ⁡ ( Q ¯ ^ ( A , W ) ) + ε ^ H ( A , W ) ) . {\displaystyle {\hat {\bar {Q}}}^{}(A,W)=\operatorname {expit} {\Big (}\operatorname {logit} {\big (}{\hat {\bar {Q}}}(A,W){\big )}+{\hat {\varepsilon }}\,H(A,W){\Big )}.} Step 5: Compute the TMLE. The ATE estimate is: ψ ^ TMLE = 1 n ∑ i = 1 n [ Q ¯ ^ ∗ ( 1 , W i ) − Q ¯ ^ ∗ ( 0 , W i ) ] . {\displaystyle {\hat {\psi }}_{\text{TMLE}}={\frac {1}{n}}\sum _{i=1}^{n}{\big [}{\hat {\bar {Q}}}^{}(1,W_{i})-{\hat {\bar {Q}}}^{}(0,W_{i}){\big ]}.} Inference. The efficient influence function (EIF) for the ATE is: D ∗ ( O ) = H ( A , W ) { Y − Q ¯ ∗ ( A , W ) } + Q ¯ ∗ ( 1 , W ) − Q ¯ ∗ ( 0 , W ) − ψ . {\displaystyle D^{}(O)=H(A,W)\{Y-{\bar {Q}}^{}(A,W)\}+{\bar {Q}}^{}(1,W)-{\bar {Q}}^{}(0,W)-\psi .} The variance is estimated by σ ^ 2 = n − 1 ∑ i = 1 n ( D ∗ ( O i ) ) 2 {\displaystyle {\hat {\sigma }}^{2}=n^{-1}\sum _{i=1}^{n}{\big (}D^{}(O_{i}){\big )}^{2}} , yielding Wald-type confidence intervals ψ ^ TMLE ± z 1 − α / 2 σ ^ / n {\displaystyle {\hat {\psi }}_{\text{TMLE}}\pm z_{1-\alpha /2}\,{\hat {\sigma }}/{\sqrt {n}}} . Remark. For continuous outcomes, a linear fluctuation Q ¯ ^ ∗ = Q ¯ ^ + ε ^ H {\displaystyle {\hat {\bar {Q}}}^{}={\hat {\bar {Q}}}+{\hat {\varepsilon }}\,H} may be used instead. For bounded continuous outcomes, the logistic fluctuation (after rescaling Y {\displaystyle Y} to [ 0 , 1 ] {\displaystyle [0,1]} ) is often preferred for improved finite-sample performance. == Applications == TMLE has been applied in: Epidemiology: Estimating causal effects of exposures and interventions in observational cohort studies. Clinical trials and real-world evidence: The Targeted Learning roadmap provides a structured framework for generating and validating real-world evidence (RWE), bridging randomized trials and observational data using TMLE and related estimation techniques. This approach enables transparency, sensitivity analysis, and stronger causal inference for regulatory and clinical trial contexts. High-dimensional settings: Integration with ensemble methods for causal effect estimation. TMLE has been successfully applied in pharmacoepidemiology where a large number of covariates are automatically selected to adjust for confounding. In a study of post–myocardial infarction statin use and 1-year mortality, TMLE demonstrated robust performance relative to inverse probability weighting in scenarios with hundreds of potential confounders. == Derivatives and extensions == Longitudinal TMLE (LTMLE): A methodological extension of TMLE for longitudinal data with time-varying treatments, confounders, and censoring. It allows the estimation of dynamic treatment regimes and intervention-specific causal effects over time. This framework was originally introduced by van der Laan & Gruber (2012). Collaborative TMLE (CTMLE): Enhances finite-sample performance and variable selection by collaboratively fitting the treatment mechanism in conjunction with the target parameter. == Software == Several R packages implement TMLE and related methods: tmle: Functions for binary, categorical, and continuous outcomes. ltmle: Implementation for longitudinal data with time-varying treatments and outcomes. ctmle: Algorithms for collaborative TMLE and adaptive variable selection. SuperLearner: A theoretically grounded, cross-validated ensemble learning method that combines predictions from multiple algorithms to minimize predictive risk. Widely used in TMLE for estimating nuisance parameters. The original implementation is available as the R package SuperLearner. Recent machine learning platforms like H2O AutoML implement similar ensemble strategies, combining diverse learners in parallel and leveraging stacking and blending techniques, effectively functioning as a large-scale Super Learner.

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  Structured kNN

  Structured k-nearest neighbours (SkNN) is a machine learning algorithm that generalizes k-nearest neighbors (k-NN). k-NN supports binary classification, multiclass classification, and regression, whereas SkNN allows training of a classifier for general structured output. For instance, a data sample might be a natural language sentence, and the output could be an annotated parse tree. Training a classifier consists of showing many instances of ground truth sample-output pairs. After training, the SkNN model is able to predict the corresponding output for new, unseen sample instances; that is, given a natural language sentence, the classifier can produce the most likely parse tree. == Training == As a training set, SkNN accepts sequences of elements with class labels. The type of element does not matter; the only requirement is a defined metric function that gives a distance between each pair of elements of a set. SkNN is based on idea of creating a graph, with each node representing a class label. There is an edge between a pair of nodes if there is a sequence of two elements in the training set with corresponding classes. The first step of SkNN training is the construction of such a graph from training sequences. There are two special nodes in the graph corresponding to sentence beginnings and ends: if a sequence starts with class C, the edge between node START and node C should be created. Like regular k-NN, the second part of SkNN training consists of storing the elements of a training sequence in a certain way. Each element of the training sequences is stored in the node related to the class of the previous element in the sequence. Every first element is stored in the START node. == Inference == Labelling input sequences by SkNN consists of finding the sequence of transitions in the graph, starting from node START. Each transition corresponds to a single element of the input sequence. As a result, the label of each element is determined as the target node label of the transition. The cost of the path is defined as the sum of all transitions, with the cost of transition from node A to node B being the distance from the current input sequence element to the nearest element of class B, stored in node A. Determining an optimal path may be performed using a modified Viterbi algorithm (where the sum of the distances is minimized, unlike the original algorithm which maximizes the product of probabilities).

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