AI Essay Verification

AI Essay Verification — independent reviews, comparisons, pricing and step-by-step guides on Aizhi.

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  ElabFTW

  eLabFTW is a web application written by Nicolas Carpi in PHP which can be used to create personal and common logbooks. It has been developed at the Curie Institute originally. Besides there, it is used on universities around the world eLabFTW is licensed under the GNU Affero General Public License as free software. It is translated into seven languages. == Description == eLabFTW is a free and open-source lab book. It is written in PHP and uses a MySQL database. Docker containers are also available. Among the various features are Secure. Entries and transmission are encrypted Timestamps. RFC 3161 compliant timestamping of experiments. Inventory management. Apart from experience logs, it also can manage the inventory Import and export. Entries can be imported and exported == Platforms == eLabFTW is a PHP package with Mysql database. Therefore, it can be executed on most servers. Furthermore, the docker containers allow to run it almost everywhere. == Usage == eLabFTW is used by various universities, like University of Alberta, Berkeley University, Hanover Medical School, Cardiff University and UMC Utrecht

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  Hyper basis function network

  In machine learning, a Hyper basis function network, or HyperBF network, is a generalization of radial basis function (RBF) networks concept, where the Mahalanobis-like distance is used instead of the Euclidean distance measure. Hyper basis function networks were first introduced by Poggio and Girosi in the 1990 paper “Networks for Approximation and Learning”. == Network Architecture == The typical HyperBF network structure consists of a real input vector x ∈ R n {\displaystyle x\in \mathbb {R} ^{n}} , a hidden layer of activation functions and a linear output layer. The output of the network is a scalar function of the input vector, ϕ : R n → R {\displaystyle \phi :\mathbb {R} ^{n}\to \mathbb {R} } , is given by where N {\displaystyle N} is a number of neurons in the hidden layer, μ j {\displaystyle \mu _{j}} and a j {\displaystyle a_{j}} are the center and weight of neuron j {\displaystyle j} . The activation function ρ j ( | | x − μ j | | ) {\displaystyle \rho _{j}(||x-\mu _{j}||)} at the HyperBF network takes the following form where R j {\displaystyle R_{j}} is a positive definite d × d {\displaystyle d\times d} matrix. Depending on the application, the following types of matrices R j {\displaystyle R_{j}} are usually considered R j = 1 2 σ 2 I d × d {\displaystyle R_{j}={\frac {1}{2\sigma ^{2}}}\mathbb {I} _{d\times d}} , where σ > 0 {\displaystyle \sigma >0} . This case corresponds to the regular RBF network. R j = 1 2 σ j 2 I d × d {\displaystyle R_{j}={\frac {1}{2\sigma _{j}^{2}}}\mathbb {I} _{d\times d}} , where σ j > 0 {\displaystyle \sigma _{j}>0} . In this case, the basis functions are radially symmetric, but are scaled with different width. R j = d i a g ( 1 2 σ j 1 2 , . . . , 1 2 σ j z 2 ) I d × d {\displaystyle R_{j}=diag\left({\frac {1}{2\sigma _{j1}^{2}}},...,{\frac {1}{2\sigma _{jz}^{2}}}\right)\mathbb {I} _{d\times d}} , where σ j i > 0 {\displaystyle \sigma _{ji}>0} . Every neuron has an elliptic shape with a varying size. Positive definite matrix, but not diagonal. == Training == Training HyperBF networks involves estimation of weights a j {\displaystyle a_{j}} , shape and centers of neurons R j {\displaystyle R_{j}} and μ j {\displaystyle \mu _{j}} . Poggio and Girosi (1990) describe the training method with moving centers and adaptable neuron shapes. The outline of the method is provided below. Consider the quadratic loss of the network H [ ϕ ∗ ] = ∑ i = 1 N ( y i − ϕ ∗ ( x i ) ) 2 {\displaystyle H[\phi ^{}]=\sum _{i=1}^{N}(y_{i}-\phi ^{}(x_{i}))^{2}} . The following conditions must be satisfied at the optimum: where R j = W T W {\displaystyle R_{j}=W^{T}W} . Then in the gradient descent method the values of a j , μ j , W {\displaystyle a_{j},\mu _{j},W} that minimize H [ ϕ ∗ ] {\displaystyle H[\phi ^{}]} can be found as a stable fixed point of the following dynamic system: where ω {\displaystyle \omega } determines the rate of convergence. Overall, training HyperBF networks can be computationally challenging. Moreover, the high degree of freedom of HyperBF leads to overfitting and poor generalization. However, HyperBF networks have an important advantage that a small number of neurons is enough for learning complex functions.

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  Preferential entailment

  Preferential entailment is a non-monotonic logic based on selecting only models that are considered the most plausible. The plausibility of models is expressed by an ordering among models called a preference relation, hence the name preference entailment. Formally, given a propositional formula F {\displaystyle F} and an ordering over propositional models ≤ {\displaystyle \leq } , preferential entailment selects only the models of F {\displaystyle F} that are minimal according to ≤ {\displaystyle \leq } . This selection leads to a non-monotonic inference relation: F ⊨ pref G {\displaystyle F\models _{\text{pref}}G} holds if and only if all minimal models of F {\displaystyle F} according to ≤ {\displaystyle \leq } are also models of G {\displaystyle G} . Circumscription can be seen as the particular case of preferential entailment when the ordering is based on containment of the sets of variables assigned to true (in the propositional case) or containment of the extensions of predicates (in the first-order logic case).

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  ICAD (software)

  ICAD (Corporate history: ICAD, Inc., Concentra (name change at IPO in 1995), KTI (name change in 1998), Dassault Systèmes (purchase in 2001) () is a knowledge-based engineering (KBE) system that enables users to encode design knowledge using a semantic representation that can be evaluated for Parasolid output. ICAD has an open architecture that can utilize all the power and flexibility of the underlying language. KBE, as implemented via ICAD, received a lot of attention due to the remarkable results that appeared to take little effort. ICAD allowed one example of end-user computing that in a sense is unparalleled. Most ICAD developers were degreed engineers. Systems developed by ICAD users were non-trivial and consisted of highly complicated code. In the sense of end-user computing, ICAD was the first to allow the power of a domain tool to be in the hands of the user, at the same time being open to allow extensions as identified and defined by the domain expert or subject-matter expert (SME). A COE article looked at the resulting explosion of expectations (see AI winter), which were not sustainable. However, such a bubble burst does not diminish the existence of ability that would exist were expectations and use reasonable or properly managed. == History == The original implementation of ICAD was on a Lisp machine (Symbolics). Some of the principals involved with the development were Larry Rosenfeld, Avrum Belzer, Patrick M. O'Keefe, Philip Greenspun, and David F. Place. The time frame was 1984–85. ICAD started on special-purpose Symbolics Lisp hardware and was then ported to Unix when Common Lisp became portable to general-purpose workstations. The original domain for ICAD was mechanical design with many application successes. However, ICAD has found use in other domains, such as electrical design, shape modeling, etc. An example project could be wind tunnel design or the development of a support tool for aircraft multidisciplinary design. Further examples can be found in the presentations at the annual IIUG (International ICAD Users Group) that have been published in the KTI Vault (1999 through 2002). Boeing and Airbus used ICAD extensively to develop various components in the 1990s and early 21st century. As of 2003, ICAD was featured strongly in several areas as evidenced by the Vision & Strategy Product Vision and Strategy presentation. After 2003, ICAD use diminished. At the end of 2001, the KTI Company faced financial difficulties and laid off most of its best staff. They were eventually bought out by Dassault who effectively scuppered the ICAD product. See IIUG at COE, 2003 (first meeting due to Dassault by KTI) The ICAD system was very expensive, relatively, and was in the price range of high-end systems. Market dynamics couldn't support this as there may not have been sufficient differentiating factors between ICAD and the lower-end systems (or the promises from Dassault). KTI was absorbed by Dassault Systèmes and ICAD is no longer considered the go-forward tool for knowledge-based engineering (KBE) applications by that company. Dassault Systèmes is promoting a suite of tools oriented around version 5 of their popular CATIA CAD application, with Knowledgeware the replacement for ICAD. As of 2005, things were still a bit unclear. ICAD 8.3 was delivered. The recent COE Aerospace Conference had a discussion about the futures of KBE. One issue involves the stacking of 'meta' issues within a computer model. How this is resolved, whether by more icons or the availability of an external language, remains to be seen. The Genworks GDL product (including kernel technology from the Gendl Project) is the nearest functional equivalent to ICAD currently available. == Particulars == ICAD provided a declarative language (IDL) using New Flavors (never converted to Common Lisp Object System (CLOS)) that supported a mechanism for relating parts (defpart) via a hierarchical set of relationships. Technically, the ICAD Defpart was a Lisp macro; the ICAD defpart list was a set of generic classes that can be instantiated with specific properties depending upon what was represented. This defpart list was extendible via composited parts that represented domain entities. Along with the part-subpart relations, ICAD supported generic relations via the object modeling abilities of Lisp. Example applications of ICAD range from a small collection of defparts that represents a part or component to a larger collection that represents an assembly. In terms of power, an ICAD system, when fully specified, can generate thousands of instances of parts on a major assembly design. One example of an application driving thousands of instances of parts is that of an aircraft wing – where fastener type and placement may number in the thousands, each instance requiring evaluation of several factors driving the design parameters. == Futures (KBE, etc.) == One role for ICAD may be serving as the defining prototype for KBE which would require that we know more about what occurred the past 15 years (much information is tied up behind corporate firewalls and under proprietary walls). With the rise of functional programming languages (an example is Haskell) in the markets, perhaps some of the power attributable to Lisp may be replicated.

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  Neuro-symbolic AI

  Neuro-symbolic AI is a subfield of artificial intelligence that integrates neural methods (e.g., neural networks and deep learning) with symbolic methods (e.g., formal logic, knowledge representation, and automated reasoning). The goal is to combine the strengths of both approaches, resulting in AI systems that can be trained from raw data and demonstrate robustness against outliers or errors in the base data, while preserving explainability, explicit use of expert knowledge, and explicit cognitive reasoning. As argued by Leslie Valiant and others, the effective construction of rich computational cognitive models demands the combination of symbolic reasoning and efficient machine learning. Gary Marcus argued, "We cannot construct rich cognitive models in an adequate, automated way without the triumvirate of hybrid architecture, rich prior knowledge, and sophisticated techniques for reasoning." Further, "To build a robust, knowledge-driven approach to AI we must have the machinery of symbol manipulation in our toolkit. Too much of useful knowledge is abstract to make do without tools that represent and manipulate abstraction, and to date, the only known machinery that can manipulate such abstract knowledge reliably is the apparatus of symbol manipulation." Angelo Dalli, Henry Kautz, Francesca Rossi, and Bart Selman also argued for such a synthesis. Their arguments attempt to address the two kinds of thinking, as discussed in Daniel Kahneman's book Thinking, Fast and Slow. It describes cognition as encompassing two components: System 1 is fast, reflexive, intuitive, and unconscious. System 2 is slower, step-by-step, and explicit. System 1 is used for pattern recognition. System 2 handles planning, deduction, and deliberative thinking. In this view, deep learning best handles the first kind of cognition, while symbolic reasoning best handles the second kind. Both are necessary for the development of a robust and reliable AI system capable of learning, reasoning, and interacting with humans to accept advice and answer questions. Since the 1990s, dual-process models with explicit references to the two contrasting systems have been the focus of research in both the fields of AI and cognitive science by numerous researchers. In 2025, the adoption of neurosymbolic AI, an approach that integrates neural networks with symbolic reasoning, increased in response to the need to address hallucination issues in large language models. For example, Amazon implemented Neurosymbolic AI in its Vulcan warehouse robots and Rufus shopping assistant to enhance accuracy and decision-making. == Approaches == Approaches for integration are diverse. Henry Kautz's taxonomy of neuro-symbolic architectures follows, along with some examples: Symbolic Neural symbolic is the current approach of many neural models in natural language processing, where words or subword tokens are the ultimate input and output of large language models. Examples include BERT, RoBERTa, and GPT-3. Symbolic[Neural] is exemplified by AlphaGo, where symbolic techniques are used to invoke neural techniques. In this case, the symbolic approach is Monte Carlo tree search and the neural techniques learn how to evaluate game positions. Neural | Symbolic uses a neural architecture to interpret perceptual data as symbols and relationships that are reasoned about symbolically. Neural-Concept Learner is an example. Neural: Symbolic → Neural relies on symbolic reasoning to generate or label training data that is subsequently learned by a deep learning model, e.g., to train a neural model for symbolic computation by using a Macsyma-like symbolic mathematics system to create or label examples. NeuralSymbolic uses a neural net that is generated from symbolic rules. An example is the Neural Theorem Prover, which constructs a neural network from an AND-OR proof tree generated from knowledge base rules and terms. Logic Tensor Networks also fall into this category. Neural[Symbolic] according to Kautz, this approach embeds true symbolic reasoning inside a neural network. These are tightly-coupled neural-symbolic systems, in which the logical inference rules are internal to the neural network. This way, the neural network internally computes the inference from the premises and learns to reason based on logical inference systems. Early work on connectionist modal and temporal logics by Garcez, Lamb, and Gabbay is aligned with this approach. These categories are not exhaustive, as they do not consider multi-agent systems. In 2005, Bader and Hitzler presented a more fine-grained categorization that took into account, e.g., whether the use of symbols included logic and, if so, whether the logic was propositional or first-order logic. The 2005 categorization and Kautz's taxonomy above are compared and contrasted in a 2021 article. Sepp Hochreiter argued that Graph Neural Networks "...are the predominant models of neural-symbolic computing" since "[t]hey describe the properties of molecules, simulate social networks, or predict future states in physical and engineering applications with particle-particle interactions." == Artificial general intelligence == Gary Marcus argues that "...hybrid architectures that combine learning and symbol manipulation are necessary for robust intelligence, but not sufficient", and that there are ...four cognitive prerequisites for building robust artificial intelligence: hybrid architectures that combine large-scale learning with the representational and computational powers of symbol manipulation, large-scale knowledge bases—likely leveraging innate frameworks—that incorporate symbolic knowledge along with other forms of knowledge, reasoning mechanisms capable of leveraging those knowledge bases in tractable ways, and rich cognitive models that work together with those mechanisms and knowledge bases. This echoes earlier calls for hybrid models as early as the 1990s. == History == Garcez and Lamb described research in this area as ongoing, at least since the 1990s. During that period, the terms symbolic and sub-symbolic AI were popular. A series of workshops on neuro-symbolic AI has been held annually since 2005 Neuro-Symbolic Artificial Intelligence. In the early 1990s, an initial set of workshops on this topic were organized. == Research == Key research questions remain, such as: What is the best way to integrate neural and symbolic architectures? How should symbolic structures be represented within neural networks and extracted from them? How should common-sense knowledge be learned and reasoned about? How can abstract knowledge that is hard to encode logically be handled? == Implementations == Implementations of neuro-symbolic approaches include: AllegroGraph: an integrated Knowledge Graph based platform for neuro-symbolic application development. Scallop: a language based on Datalog that supports differentiable logical and relational reasoning. Scallop can be integrated in Python and with a PyTorch learning module. Logic Tensor Networks: encode logical formulas as neural networks and simultaneously learn term encodings, term weights, and formula weights. DeepProbLog: combines neural networks with the probabilistic reasoning of ProbLog. Abductive Learning: integrates machine learning and logical reasoning in a balanced-loop via abductive reasoning, enabling them to work together in a mutually beneficial way. SymbolicAI: a compositional differentiable programming library.

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  AlphaGo Zero

  AlphaGo Zero is a version of DeepMind's Go software AlphaGo. AlphaGo's team published an article in Nature in October 2017 introducing AlphaGo Zero, a version created without using data from human games, and stronger than any previous version. By playing games against itself, AlphaGo Zero: surpassed the strength of AlphaGo Lee in three days by winning 100 games to 0; reached the level of AlphaGo Master in 21 days; and exceeded all previous versions in 40 days. Training artificial intelligence (AI) without datasets derived from human experts has significant implications for the development of AI with superhuman skills, as expert data is "often expensive, unreliable, or simply unavailable." Demis Hassabis, the co-founder and CEO of DeepMind, said that AlphaGo Zero was so powerful because it was "no longer constrained by the limits of human knowledge". Furthermore, AlphaGo Zero performed better than standard deep reinforcement learning models (such as Deep Q-Network implementations) due to its integration of Monte Carlo tree search. David Silver, one of the first authors of DeepMind's papers published in Nature on AlphaGo, said that it is possible to have generalized AI algorithms by removing the need to learn from humans. Google later developed AlphaZero, a generalized version of AlphaGo Zero that could play chess and shōgi in addition to Go. In December 2017, AlphaZero beat the 3-day version of AlphaGo Zero by winning 60 games to 40, and with 8 hours of training it outperformed AlphaGo Lee on an Elo scale. AlphaZero also defeated a top chess program (Stockfish) and a top Shōgi program (Elmo). == Architecture == The network in AlphaGo Zero is a ResNet with two heads. The stem of the network takes as input a 17x19x19 tensor representation of the Go board. 8 channels are the positions of the current player's stones from the last eight time steps. (1 if there is a stone, 0 otherwise. If the time step go before the beginning of the game, then 0 in all positions.) 8 channels are the positions of the other player's stones from the last eight time steps. 1 channel is all 1 if black is to move, and 0 otherwise. The body is a ResNet with either 20 or 40 residual blocks and 256 channels. There are two heads, a policy head and a value head. Policy head outputs a logit array of size 19 × 19 + 1 {\displaystyle 19\times 19+1} , representing the logit of making a move in one of the points, plus the logit of passing. Value head outputs a number in the range ( − 1 , + 1 ) {\displaystyle (-1,+1)} , representing the expected score for the current player. -1 represents current player losing, and +1 winning. == Training == AlphaGo Zero's neural network was trained using TensorFlow, with 64 GPU workers and 19 CPU parameter servers. Only four TPUs were used for inference. The neural network initially knew nothing about Go beyond the rules. Unlike earlier versions of AlphaGo, Zero only perceived the board's stones, rather than having some rare human-programmed edge cases to help recognize unusual Go board positions. The AI engaged in reinforcement learning, playing against itself until it could anticipate its own moves and how those moves would affect the game's outcome. In the first three days AlphaGo Zero played 4.9 million games against itself in quick succession. It appeared to develop the skills required to beat top humans within just a few days, whereas the earlier AlphaGo took months of training to achieve the same level. According to Epoch.ai, training cost 3e23 FLOPs. For comparison, the researchers also trained a version of AlphaGo Zero using human games, AlphaGo Master, and found that it learned more quickly, but actually performed more poorly in the long run. DeepMind submitted its initial findings in a paper to Nature in April 2017, which was then published in October 2017. == Hardware cost == The hardware cost for a single AlphaGo Zero system in 2017, including the four TPUs, has been quoted as around $25 million. == Applications == According to Hassabis, AlphaGo's algorithms are likely to be of the most benefit to domains that require an intelligent search through an enormous space of possibilities, such as protein folding (see AlphaFold) or accurately simulating chemical reactions. AlphaGo's techniques are probably less useful in domains that are difficult to simulate, such as learning how to drive a car. DeepMind stated in October 2017 that it had already started active work on attempting to use AlphaGo Zero technology for protein folding, and stated it would soon publish new findings. == Reception == AlphaGo Zero was widely regarded as a significant advance, even when compared with its groundbreaking predecessor, AlphaGo. Oren Etzioni of the Allen Institute for Artificial Intelligence called AlphaGo Zero "a very impressive technical result" in "both their ability to do it—and their ability to train the system in 40 days, on four TPUs". The Guardian called it a "major breakthrough for artificial intelligence", citing Eleni Vasilaki of Sheffield University and Tom Mitchell of Carnegie Mellon University, who called it an impressive feat and an “outstanding engineering accomplishment" respectively. Mark Pesce of the University of Sydney called AlphaGo Zero "a big technological advance" taking us into "undiscovered territory". Gary Marcus, a psychologist at New York University, has cautioned that for all we know, AlphaGo may contain "implicit knowledge that the programmers have about how to construct machines to play problems like Go" and will need to be tested in other domains before being sure that its base architecture is effective at much more than playing Go. In contrast, DeepMind is "confident that this approach is generalisable to a large number of domains". In response to the reports, South Korean Go professional Lee Sedol said, "The previous version of AlphaGo wasn’t perfect, and I believe that’s why AlphaGo Zero was made." On the potential for AlphaGo's development, Lee said he will have to wait and see but also said it will affect young Go players. Mok Jin-seok, who directs the South Korean national Go team, said the Go world has already been imitating the playing styles of previous versions of AlphaGo and creating new ideas from them, and he is hopeful that new ideas will come out from AlphaGo Zero. Mok also added that general trends in the Go world are now being influenced by AlphaGo's playing style. "At first, it was hard to understand and I almost felt like I was playing against an alien. However, having had a great amount of experience, I’ve become used to it," Mok said. "We are now past the point where we debate the gap between the capability of AlphaGo and humans. It’s now between computers." Mok has reportedly already begun analyzing the playing style of AlphaGo Zero along with players from the national team. "Though having watched only a few matches, we received the impression that AlphaGo Zero plays more like a human than its predecessors," Mok said. Chinese Go professional Ke Jie commented on the remarkable accomplishments of the new program: "A pure self-learning AlphaGo is the strongest. Humans seem redundant in front of its self-improvement." == Comparison with predecessors == == AlphaZero == On 5 December 2017, DeepMind team released a preprint on arXiv, introducing AlphaZero, a program using generalized AlphaGo Zero's approach, which achieved within 24 hours a superhuman level of play in chess, shogi, and Go, defeating world-champion programs, Stockfish, Elmo, and 3-day version of AlphaGo Zero in each case. AlphaZero (AZ) is a more generalized variant of the AlphaGo Zero (AGZ) algorithm, and is able to play shogi and chess as well as Go. Differences between AZ and AGZ include: AZ has hard-coded rules for setting search hyperparameters. The neural network is now updated continually. Chess (unlike Go) can end in a tie; therefore AZ can take into account the possibility of a tie game. An open source program, Leela Zero, based on the ideas from the AlphaGo papers is available. It uses a GPU instead of the TPUs recent versions of AlphaGo rely on.

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  Eimear Kenny

  Eimear E. Kenny is a researcher in population genetics and translation genomics, and is the Founding Director of the Institute for Genomic Health, and Endowed Chair and Professor of Genomic Health at the Icahn School of Medicine at Mount Sinai. She is known for novel approaches in computational genomics, advancing the study of human genetic variation and its connection to disease risk and diagnosis. Her research has laid the foundation for integrating artificial intelligence (AI) and genomics into precision medicine and routine clinical care. By combining genomics, computer science, and medicine, her work leverages genomic sequencing technologies and machine learning algorithms to uncover insights that improve patient care, accelerate genomic data analysis, and enable the future of AI-driven healthcare. She has led multiple genomics-based clinical trials, applying computational biology and AI in clinical settings to advance genomic medicine and precision healthcare. == Research == A recipient of the Early-Career Award from the American Society of Human Genetics (USA), Kenny, as of 2024, leads a team in genetics, computer science, and medicine, focusing on genetic ancestry, large-scale genomics, clinical trials, and genomic medicine at the Institute for Genomic Health. The lab works to advance understanding of genetic ancestry and its impact on health in order to inform better clinical medicine models. She is recognized for her work to leverage biobanks for translational genomics and her development of new genetic tests an strategies for health care management. In one study, she and her colleagues investigated genetic disorders that might be under-diagnosed due to insufficient data, and found a variant in a collagen gene associated with Steel syndrome. This syndrome caused short stature and bone and joint issues and was thought to be rare. However, the study revealed it is common in individuals with Puerto Rican ancestry. Three of Kenny's genomic medicine clinical trials assessed how to bring new technology, such as digital apps, or information, such as polygenic risk scores, into routine clinical care. In the 2010s, Kenny was instrumental in several large-scale sequencing studies, including the 1000 Genomes Project, the Exome Sequencing Project, the Genome Sequencing Project, and the Trans-Omics for Precision Medicine. In 2012, she led work that discovered the variant responsible for blond hair in Melanesia, work that was featured in the Smithsonian NHGRI Human Genome Exhibit in Washington, D.C. In 2017, her group was one of the first to demonstrate that polygenic risk scores derived in predominantly European populations have reduced accuracy when applied in populations now widely acknowledged as a major challenge in the field of genomic risk prediction. As of 2024, she is Principal Investigator in many NIH-funded international consortium focused on computational genomics and genomic medicine, including Electronic Medical Records and Genomics, Polygenic Risk Methods in Diverse Populations, and the Human Pangenome Reference Consortium. In 2023, Kenny played a key role in a groundbreaking advancement in genomics research by helping to map a diverse human pangenome—a major shift from reliance on a single reference genome. Unlike the earlier genetic map, based on one man of mixed European and African ancestry in Buffalo, this new pangenome project captures far greater human genetic diversity. As reported by The Washington Post, Kenny's work demonstrates how a more inclusive human genome can drive discoveries in rare genetic diseases, improve genomic medicine, and accelerate the future of precision healthcare. Kenny was co-developer and current license holder for Random Forest adMIXture (RFMix), a patented software for inferring continental and sub-continental ancestry at genomic loci. == Education and career == Kenny graduated from Trinity College Dublin with a BA in Biochemistry in 1999 and did a masters in Bioinformatics at Leeds University. She received her PhD in Computational Genomics at Rockefeller University, and did her post-doctoral work in the lab of Dr. Carlos D. Bustamante at Stanford University. === Academic appointments === As of 2024, at Mount Sinai, she serves as the Endowed Chair and Professor of Genomic Health, Professor at the Department of Medicine and Professor at the Department of Genetics and Genomic Sciences. Since 2018 she has served as the Founding Director of the Institute for Genomic Health, and since 2022, she also serves as the Founding Director of the Center for Translational Genomics. She is also the Director of Translational Research, Division for Genomic Medicine. Former appointments include Assistant Professor at the Department of Genetics and Genomic Sciences and Member at The Charles Bronfman Institute of Personalized Medicine, both at Mount Sinai. She was also Bioinformatics Programmer at the California Institute of Technology, and research assistant at the Massachusetts Institute of Technology. == Publications == As of 2024, Kenny is an advisor to Cell Genomics. Google Scholar reports 50,623 citations, an h-index of 66 and an i10-index of 130. The five most-cited articles she contributed to are: Auton, A; Brooks, LD; Durbin, RM; Garrison, EP; Kang, HM; Korbel, JO; Marchini, JL; McCarthy, S; McVean, GA; Abecasis, GR (2015). "A global reference for human genetic variation". Nature. 526 (7571): 68–74. Bibcode:2015Natur.526...68T. doi:10.1038/nature15393. PMC 4750478. PMID 26432245.. Cited by 14847 Abecasis, GR; Auton, A; Brooks, LD; DePristo, MA; Durbin, RM; Handsaker, RE; Kang, HM; Marth, GT; McVean, GA (2012). "An integrated map of genetic variation from 1,092 human genomes". Nature. 491 (7422): 56–65. Bibcode:2012Natur.491...56T. doi:10.1038/nature11632. PMC 3498066. PMID 23128226.. Cited by 8287 Jacob A. Tennessen et al. Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes.Science337,64–69(2012).DOI:10.1126/science.1219240 Cited by 1886 Taliun, D.; Harris, D.N.; Kessler, M.D.; et al. (2021). "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program". Nature. 590 (7845): 290–299. Bibcode:2021Natur.590..290T. doi:10.1038/s41586-021-03205-y. PMC 7875770. PMID 33568819.. Cited by 1369 Vilhjálmsson, BJ; et al. (2015). "Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores". Am J Hum Genet. 97 (4): 576–92. doi:10.1016/j.ajhg.2015.09.001. PMC 4596916. PMID 26430803.. Cited by 1327

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  Unique name assumption

  The unique name assumption is a simplifying assumption made in some ontology languages and description logics. In logics with the unique name assumption, different names always refer to different entities in the world. It was included in Ray Reiter's discussion of the closed-world assumption often tacitly included in Database Management Systems (e.g. SQL) in his 1984 article "Towards a logical reconstruction of relational database theory" (in M. L. Brodie, J. Mylopoulos, J. W. Schmidt (editors), Data Modelling in Artificial Intelligence, Database and Programming Languages, Springer, 1984, pages 191–233). The standard ontology language OWL does not make this assumption, but provides explicit constructs to express whether two names denote the same or distinct entities. owl:sameAs is the OWL property that asserts that two given names or identifiers (e.g., URIs) refer to the same individual or entity. owl:differentFrom is the OWL property that asserts that two given names or identifiers (e.g., URIs) refer to different individuals or entities.

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  Quantum natural language processing

  Quantum natural language processing (QNLP) is the application of quantum computing to natural language processing (NLP). It computes word embeddings as parameterised quantum circuits that can solve NLP tasks faster than any classical computer. It is inspired by categorical quantum mechanics and the DisCoCat framework, making use of string diagrams to translate from grammatical structure to quantum processes. == Theory == The first quantum algorithm for natural language processing used the DisCoCat framework and Grover's algorithm to show a quadratic quantum speedup for a text classification task. It was later shown that quantum language processing is BQP-Complete, i.e. quantum language models are more expressive than their classical counterpart, unless quantum mechanics can be efficiently simulated by classical computers. These two theoretical results assume fault-tolerant quantum computation and a QRAM, i.e. an efficient way to load classical data on a quantum computer. Thus, they are not applicable to the noisy intermediate-scale quantum (NISQ) computers available today. == Experiments == The algorithm of Zeng and Coecke was adapted to the constraints of NISQ computers and implemented on IBM quantum computers to solve binary classification tasks. Instead of loading classical word vectors onto a quantum memory, the word vectors are computed directly as the parameters of quantum circuits. These parameters are optimised using methods from quantum machine learning to solve data-driven tasks such as question answering, machine translation and even algorithmic music composition.

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  Minion (solver)

  Minion is a solver for satisfaction problems. Unlike constraint programming toolkits, which expect users to write programs in a traditional programming language like C++, Java or Prolog, Minion takes a text file which specifies the problem, and solves using only this. This makes using Minion much simpler, at the cost of much less customization. Minion has been shown to be faster than major commercial constraint solvers including CPLEX (formerly IBM ILOG). == Overview == Minion was introduced in 2006 by researchers at the University of St Andrews as a “fast, scalable” solver for large and hard CSP instances. The project provides a compact input language and a low-overhead C++ implementation aimed at throughput and memory efficiency. == Design and features == Minion implements a range of variable and constraint types commonly used in CSP modelling, plus search heuristics and optimisation support. The solver architecture prioritises cache-friendly data structures and specialised propagators. Notably, the developers adapted watched literal techniques from SAT solving to speed up constraint propagation for, among others, Boolean sums, the element global constraint, and table constraints. The modelling approach relies on a plain-text format (parsed by Minion) rather than embedding models into a host programming language. This reduces overhead and supports rapid “model-and-run” experimentation for large benchmark sets. == Performance == In the original evaluation on standard benchmarks, the authors reported that Minion often ran between one and two orders of magnitude faster than state-of-the-art toolkits of the time (including ILOG Solver and Gecode) on large, hard instances, with smaller gains—or slowdowns—on easier problems. Subsequent research has used Minion as a baseline solver in empirical studies and test generation tasks, reflecting its adoption within parts of the constraint programming community. == Applications == Minion has been applied in academic work on combinatorial search, scheduling and test generation, and is available to other environments via wrappers (for example, from the R language).

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  R2ML

  The REWERSE Rule Markup Language (R2ML) is developed by the REWERSE Working Group I1 for the purpose of rules interchange between different systems and tools. == Scope == An XML based rule language; Support for: integrity rules, derivation rules, production rules and reaction rules; Integrate functional languages (such as OCL) with Datalog languages (such as SWRL); Serialization and interchange of rules by specific software tools; Integrating rule reasoning with actual server side technologies; Deploying, publishing and communicating rules in a network. == Design principles == Modeled using MDA; Rule concepts defined with the help of MOF/UML; Required to accommodate: Web naming concepts, such as URIs and XML namespaces; The ontological distinction between objects and data values; The datatype concepts of RDF and user-defined datatypes; Actions (following OMG PRR submission); Events; EBNF abstract syntax; XML based concrete syntax validated by an XML Schema; Allowing different semantics for rules.

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  National Library of Medicine classification

  The National Library of Medicine (NLM) classification system is a library indexing system covering the fields of medicine and preclinical basic sciences. Operated and maintained by the U.S. National Library of Medicine, the NLM classification is patterned after the Library of Congress (LC) Classification system: alphabetical letters denote broad subject categories which are subdivided by numbers. For example, QW 279 would indicate a book on an aspect of microbiology or immunology. The one- or two-letter alphabetical codes in the NLM classification use a limited range of letters: only QS–QZ and W–WZ. This allows the NLM system to co-exist with the larger LC coding scheme as neither of these ranges are used in the LC system. There are, however, three pre-existing codes in the LC system which overlap with the NLM: Human Anatomy (QM), Microbiology (QR), and Medicine (R). To avoid further confusion, these three codes are not used in the NLM. The headings for the individual schedules (letters or letter pairs) are given in brief form (e.g., QW - Microbiology and Immunology; WG - Cardiovascular System) and together they provide an outline of the subjects covered by the NLM classification. Headings are interpreted broadly and include the physiological system, the specialties connected with them, the regions of the body chiefly concerned and subordinate related fields. The NLM system is hierarchical, and within each schedule, division by organ usually has priority. Each main schedule, as well as some sub-sections, begins with a group of form numbers ranging generally from 1–49 which classify materials by publication type, e.g., dictionaries, atlases, laboratory manuals, etc. The main schedules QS-QZ, W-WY, and WZ (excluding the range WZ 220–270) classify works published after 1913; the 19th century schedule is used for works published 1801–1913; and WZ 220-270 is used to provide century groupings for works published before 1801. == Classification categories == === Preclinical Sciences === QS Human Anatomy QT Physiology QU Biochemistry QV Pharmacology QW Microbiology & Immunology QX Parasitology QY Clinical Pathology QZ Pathology === Medicine and Related Subjects === W Health Professions WA Public Health WB Practice of Medicine WC Communicable Diseases WD Disorders of Systemic, Metabolic, or Environmental Origin, etc. WE Musculoskeletal System WF Respiratory System WG Cardiovascular System WH Hemic and Lymphatic Systems WI Digestive System WJ Urogenital System WK Endocrine System WL Nervous System WM Psychiatry WN Radiology. Diagnostic Imaging WO Surgery WP Gynecology WQ Obstetrics WR Dermatology WS Pediatrics WT Geriatrics. Chronic Disease WU Dentistry. Oral Surgery WV Otolaryngology WW Ophthalmology WX Hospitals & Other Health Facilities WY Nursing WZ History of Medicine 19th Century Schedule

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  Engineering Historical Memory

  Engineering Historical Memory (EHM) is an online database in the digital humanities, serving as an open-access research tool for primary historical materials focused on 11th to 15th century Afro-Eurasia. It adopts computational methods to make historical documents machine-understandable. EHM parses traditional artifacts such as historical maps, travel accounts, chronicles and codices into computer-readable formats, and links them to secondary multi-media references, a process referred to as the "automatic narrative generation". This approach generates cultural narratives and facilitates interaction with the historical artifacts, making them accessible to audiences from various backgrounds. == History == EHM was first theorised in 2007 by researcher Andrea Nanetti when he was a visiting scholar at Princeton University, and the preliminary test results were published between 2008 and 2011. In 2013, the EHM research team was set up in Singapore following Nanetti's professorship at Nanyang Technological University (NTU). Two years later, after receiving several Microsoft research grants, EHM went live on Microsoft Azure. In 2018, the College of Humanities, Arts and Social Sciences (CoHASS) at NTU Singapore formed the Digital Humanities Research Cluster, as part of which, EHM has been an ongoing interdisciplinary research project led by Nanetti. Partnering with international educational and cultural institutions such as Ca' Foscari University of Venice, University of Florence, Taylor & Francis Group, Delft University of Technology (TUDelft), and SenticNet, EHM has been supported by over 130 scholars and engineers. == Applications == Primary historical materials on EHM are curated into several categories, including maps, travel accounts, chronicles, codices, sites, archival documents, and paintings, such as the Morosini Codex (listed under Chronicles) and Pope Gregory X's Privilege for the Holy Monastery of St Catherine of Sinai (listed under Archival Documents). EHM has been adopted by cultural organisations as an exhibition and research tool in the digital humanities field. An example is the publication of a digital interactive edition of Fra Mauro's Map of the World on EHM, a collaboration project between NTU Singapore and the Biblioteca Nazionale Marciana of Venice. The digitisation process of the map on EHM involved transcribing and geo-referencing the textual content in the 15th-century map, followed by creating semantic annotations to connect the map's content with related secondary data sources. The e-map was subsequently adopted and launched online by Museo Galileo in March 2022 and incorporated into the virtual exhibition "Venezia and Suzhou: Water Cities along the Silk Roads" (online, September-December 2022). In 2024, the Fra Mauro's Map of the World application on EHM was awarded the Digital Humanities and Multimedia Studies Prize (DHMS) by the Medieval Academy of America. Image-Based Video Search Engine is another experimental project under the EHM scope led by the research teams at Delft University of Technology (TUDelft) and NTU Singapore. This ongoing project aims to improve the efficiency of retrieving targeted objects from audio-visuals. == Awards == In 2021, EHM won the GLAMi Awards (MuseWeb Conference - Galleries, Libraries, Archives, and Museums Innovation awards) in the "Resources for Scholars and Researchers" category. In the same year, EHM was a Falling Walls finalist for Science Breakthrough of the Year in the category Social Sciences and Humanities after nominated by the School of Advanced Study at the University of London. In April 2022, the Italian National Commission for UNESCO has selected and sent the EHM project to the organisers of the "Jikji Memory of the World" Award for final evaluation. In January 2024, the Medieval Academy of America announced its 2024 Digital Humanities and Multimedia Studies Prize (DHMS) goes to the Fra Mauro's Map of the World application on EHM.

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  Protégé (software)

  Protégé is a free, open source ontology editor and a knowledge management system. The Protégé meta-tool was first built by Mark Musen in 1987 and has since been developed by a team at Stanford University. The software is the most popular and widely used ontology editor in the world. == Overview == Protégé provides a graphical user interface to define ontologies. It also includes deductive classifiers to validate that models are consistent and to infer new information based on the analysis of an ontology. Like Eclipse, Protégé is a framework for which various other projects suggest plugins. This application is written in Java and makes heavy use of Swing to create the user interface. According to their website, there are over 300,000 registered users. A 2009 book calls it "the leading ontological engineering tool". Protégé is developed at Stanford University and is made available under the BSD 2-clause license. Earlier versions of the tool were developed in collaboration with the University of Manchester.

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  Linagora

  Linagora is a French open source software editor, founded in June 2000 by Alexandre Zapolsky and Michel-Marie Maudet. Located in France, as well as in Belgium, Canada, Vietnam, the United States and Tunisia, the company employs around 200 people. In 2023, Linagora created the OpenLLM France community, alongside other French Artificial Intelligence companies and organizations. In 2025, the company launched Lucie, an opensource Large Language Model. == History == Linagora was founded on June 28, 2000. Its name is a contraction of the words "Linux" and "Agora". The company was founded by Alexandre Zapolsky and Michel-Marie Maudet. Soon after, the two entrepreneurs were joined by Alexandre Zapolsky's wife and brother, who took on the roles of commercial director and administrative and financial director of the SME. In 2007, the company was selected by the French National Assembly to provide the software for Linux computers, replacing Microsoft Windows. Linagora then claimed the position of the leading French open source software company by revenue. In 2015, French Prime Minister Manuel Valls allocated €10.7 million from the "Investments for the Future" fund for a research program aimed at developing a new generation of open source software platforms based on Linagora's offerings. In September 2016, Linagora launched the social network "La Cerise" for the newspaper L'Humanité. This app offered a service and tool for readers and citizens mobilizing for causes. It aimed to share engagement through petitions, discussions, agendas, and contacts. In October 2016, the company won two public contracts for supporting open source software in forty-two French ministries and other administrative entities. In May 2019, Linagora organized a fundraising event in the presence of the French Secretary of State for Digital Affairs, Cédric O, to celebrate its 19th anniversary. The funds were intended for: Supporting parents of hospitalized Polynesian children in France. Equipping primary school students with digital devices (tablets or PCs). Establishing a digital academy "OpenHackademy" in French Polynesia to train unemployed youth in digital skills and help them find jobs. In December 2022, Linagora acquired a property known as "Maison Rocher" and later "Maison Chocolat," located on the Île Saint-Germain in Issy-les-Moulineaux. Renamed "Villa Good Tech" by Linagora, this award-winning architectural work by Éric Daniel-Lacombe became the company's new headquarters, aiming to provide a space for associative actors and companies to develop technologies that contribute to a better world. In July 2023, Linagora launched OpenLLM France, a community initially comprising around twenty actors focused on generative AI. The goal was to develop a sovereign and open source large language model. This initiative, led by co-founder and CEO Michel-Marie Maudet, had more than four hundred French members by early 2024. and announced its expansion to the European sphere during Fosdem 2024. In February 2024, the CNRS and Linagora signed a framework agreement to strengthen their research collaboration. In January 2025, Linagora released Lucie, an open source and sovereign AI that faced ridicule due to tests on an unfinished, uncensored version designed for scientific and experimental use. The platform divided opinions between those who saw it as a technological achievement and those who criticized it as "French bashing" compared to American and Chinese AIs. == Acquisitions == The company acquired: In July 2007, the SME AliaSource, based in Ramonville-Saint-Agne and led by its founder, Pierre Baudracco. In 2008, the open source web hosting company Netaktiv, a member of the GIE Gitoyen, announced during the 2008 Solutions Linux trade show. In 2012, the Toulouse-based company EBM Websourcing, the publisher of the open-source software Petals Link, and took over its development. In 2016, the digital agency Neoma Interactive, specializing in UX design and digital communication strategy. == Locations == In 2017, the company's headquarters was located in Issy-les-Moulineaux, with branches in Lyon, Toulouse, Marseille, and internationally in Brussels, San Francisco, Montreal, Vietnam, and Tunisia. In 2005, the company attempted to establish a presence in Nantes. In 2024, the headquarters was moved to Issy-les-Moulineaux. == Activity == === Software === Twake Workplace One of Linagora's flagship products is Twake Workplace, which stands out as a 100% open-source solution compared with those of the GAFAMs. Twake Workplace is available as a complete platform or module by module. It includes : Twake Mail, a powerful modern messaging solution based on the JMAP protocol and the James email server from the Apache Foundation, for which Linagora provides technical management; Twake Chat, an instant communications solution for businesses developed using the Matrix protocol and compatible with the French government's chat solution, Tchap; Twake Drive, an easy-to-use collaborative platform for group work using OnlyOffice. ==== OpenPaaS ==== In 2018, the search engine Qwant announced that its email service Qwantmail would be based on the OpenPaaS product. In 2022, Qwant announced the abandonment of its Qwantmail project due to Linagora's collection of personal email addresses and serious security breaches. The site Next (formerly PC INpact) published an article in January 2020 criticizing the "failures and delays" of the Qwantmail project led by Linagora, which led to the CNIL's intervention regarding Qwant and Linagora. ==== LinTO ==== In 2017, Linagora launched its open source voice assistant project named LinTO. This enterprise voice assistant, described as "GAFAM Free," was presented at CES 2018 in Las Vegas. The LinTO voice framework was developed as part of the eponymous research project funded by Bpifrance (Grands Défis du Numérique instrument). === Services === ==== OSSA (Open Source Software Assurance) ==== One of the company's main activities is OSSA. Through OSSA, Linagora provided support for open source software for 42 ministries and other administrative entities in 2012. == Legal issues == === Dispute with BlueMind === In 2012, a legal dispute arose between BlueMind and Linagora. Linagora accused BlueMind of copyright infringement, unfair competition, and breach of a non-compete clause, leading to several legal actions. Linagora sued BlueMind for copyright infringement and unfair competition in the Bordeaux court, which ruled in Linagora's favor for unfair competition and parasitism but rejected the copyright claim. BlueMind was ordered to pay nearly €170,000 to Linagora. Linagora sued former associates Pierre Baudracco and Pierre Carlier in the Paris Commercial Court for breach of a non-compete clause and violation of a warranty of eviction. The court dismissed Linagora's claims and ordered it to pay €20,000 each to Baudracco and Carlier. Linagora appealed, and the Paris Court of Appeal partially overturned the decision, awarding Linagora €480,000. BlueMind sued Linagora for defamation and public insult in the Toulouse Criminal Court. The court ruled against Linagora, but the decision was overturned by the Court of Cassation in January 2024, and the case was remanded for retrial. === Conviction for wrongful termination and harassment === On June 14, 2017, France 3 reported on a decision by the Versailles Court of Appeal, which ruled that Linagora had wrongfully terminated an employee and subjected them to moral harassment. The court ordered Linagora to pay the employee €22,000 for wrongful termination, €11,000 for notice pay, €6,600 for legal severance pay, €3,200 for conservative suspension, and €3,000 for moral harassment.

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