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Biohybrid microswimmer

A biohybrid microswimmer also known as biohybrid nanorobot, can be defined as a microswimmer that consist of both biological and artificial constituents, for instance, one or several living microorganisms attached to one or various synthetic parts. In recent years nanoscopic and mesoscopic objects have been designed to collectively move through direct inspiration from nature or by harnessing its existing tools. Small mesoscopic to nanoscopic systems typically operate at low Reynolds numbers (Re ≪ 1), and understanding their motion becomes challenging. For locomotion to occur, the symmetry of the system must be broken. In addition, collective motion requires a coupling mechanism between the entities that make up the collective. To develop mesoscopic to nanoscopic entities capable of swarming behaviour, it has been hypothesised that the entities are characterised by broken symmetry with a well-defined morphology, and are powered with some material capable of harvesting energy. If the harvested energy results in a field surrounding the object, then this field can couple with the field of a neighbouring object and bring some coordination to the collective behaviour. Such robotic swarms have been categorised by an online expert panel as among the 10 great unresolved group challenges in the area of robotics. Although investigation of their underlying mechanism of action is still in its infancy, various systems have been developed that are capable of undergoing controlled and uncontrolled swarming motion by harvesting energy (e.g., light, thermal, etc.). Over the past decade, biohybrid microrobots, in which living mobile microorganisms are physically integrated with untethered artificial structures, have gained growing interest to enable the active locomotion and cargo delivery to a target destination. In addition to the motility, the intrinsic capabilities of sensing and eliciting an appropriate response to artificial and environmental changes make cell-based biohybrid microrobots appealing for transportation of cargo to the inaccessible cavities of the human body for local active delivery of diagnostic and therapeutic agents. == Background == Biohybrid microswimmers can be defined as microswimmers that consist of both biological and artificial constituents, for instance, one or several living microorganisms attached to one or various synthetic parts. The pioneers of this field, ahead of their time, were Montemagno and Bachand with a 1999 work regarding specific attachment strategies of biological molecules to nanofabricated substrates enabling the preparation of hybrid inorganic/organic nanoelectromechanical systems, so called NEMS. They described the production of large amounts of F1-ATPase from the thermophilic bacteria Bacillus PS3 for the preparation of F1-ATPase biomolecular motors immobilized on a nanoarray pattern of gold, copper or nickel produced by electron beam lithography. These proteins were attached to one micron microspheres tagged with a synthetic peptide. Consequently, they accomplished the preparation of a platform with chemically active sites and the development of biohybrid devices capable of converting energy of biomolecular motors into useful work. One of the most fundamental questions in science is what defines life. Collective motion is one of the hallmarks of life. This is commonly observed in nature at various dimensional levels as energized entities gather, in a concerted effort, into motile aggregated patterns. These motile aggregated events can be noticed, among many others, as dynamic swarms; e.g., unicellular organisms such as bacteria, locust swarms, or the flocking behaviour of birds. Ever since Newton established his equations of motion, the mystery of motion on the microscale has emerged frequently in scientific history, as famously demonstrated by a couple of articles that should be discussed briefly. First, an essential concept, popularized by Osborne Reynolds, is that the relative importance of inertia and viscosity for the motion of a fluid depends on certain details of the system under consideration. The Reynolds number Re, named in his honor, quantifies this comparison as a dimensionless ratio of characteristic inertial and viscous forces: R e = ρ u l μ {\displaystyle \mathrm {Re} ={\frac {\rho ul}{\mu }}} Here, ρ represents the density of the fluid; u is a characteristic velocity of the system (for instance, the velocity of a swimming particle); l is a characteristic length scale (e.g., the swimmer size); and μ is the viscosity of the fluid. Taking the suspending fluid to be water, and using experimentally observed values for u, one can determine that inertia is important for macroscopic swimmers like fish (Re = 100), while viscosity dominates the motion of microscale swimmers like bacteria (Re = 10−4). The overwhelming importance of viscosity for swimming at the micrometer scale has profound implications for swimming strategy. This has been discussed memorably by E. M. Purcell, who invited the reader into the world of microorganisms and theoretically studied the conditions of their motion. In the first place, propulsion strategies of large scale swimmers often involve imparting momentum to the surrounding fluid in periodic discrete events, such as vortex shedding, and coasting between these events through inertia. This cannot be effective for microscale swimmers like bacteria: due to the large viscous damping, the inertial coasting time of a micron-sized object is on the order of 1 μs. The coasting distance of a microorganism moving at a typical speed is about 0.1 angstroms (Å). Purcell concluded that only forces that are exerted in the present moment on a microscale body contribute to its propulsion, so a constant energy conversion method is essential. Microorganisms have optimized their metabolism for continuous energy production, while purely artificial microswimmers (microrobots) must obtain energy from the environment, since their on-board-storage-capacity is very limited. As a further consequence of the continuous dissipation of energy, biological and artificial microswimmers do not obey the laws of equilibrium statistical physics, and need to be described by non-equilibrium dynamics. Mathematically, Purcell explored the implications of low Reynolds number by taking the Navier-Stokes equation and eliminating the inertial terms: μ ∇ 2 u − ∇ p = 0 {\displaystyle {\begin{aligned}\mu \nabla ^{2}\mathbf {u} -{\boldsymbol {\nabla }}p&={\boldsymbol {0}}\\\end{aligned}}} where u {\displaystyle \mathbf {u} } is the velocity of the fluid and ∇ p {\displaystyle {\boldsymbol {\nabla }}p} is the gradient of the pressure. As Purcell noted, the resulting equation — the Stokes equation — contains no explicit time dependence. This has some important consequences for how a suspended body (e.g., a bacterium) can swim through periodic mechanical motions or deformations (e.g., of a flagellum). First, the rate of motion is practically irrelevant for the motion of the microswimmer and of the surrounding fluid: changing the rate of motion will change the scale of the velocities of the fluid and of the microswimmer, but it will not change the pattern of fluid flow. Secondly, reversing the direction of mechanical motion will simply reverse all velocities in the system. These properties of the Stokes equation severely restrict the range of feasible swimming strategies. Recent publications of biohybrid microswimmers include the use of sperm cells, contractive muscle cells, and bacteria as biological components, as they can efficiently convert chemical energy into movement, and additionally are capable of performing complicated motion depending on environmental conditions. In this sense, biohybrid microswimmer systems can be described as the combination of different functional components: cargo and carrier. The cargo is an element of interest to be moved (and possibly released) in a customized way. The carrier is the component responsible for the movement of the biohybrid, transporting the desired cargo, which is linked to its surface. The great majority of these systems rely on biological motile propulsion for the transportation of synthetic cargo for targeted drug delivery/ There are also examples of the opposite case: artificial microswimmers with biological cargo systems. Over the past decade, biohybrid microrobots, in which living mobile microorganisms are physically integrated with untethered artificial structures, have gained growing interest to enable the active locomotion and cargo delivery to a target destination. In addition to the motility, the intrinsic capabilities of sensing and eliciting an appropriate response to artificial and environmental changes make cell-based biohybrid microrobots appealing for transportation of cargo to the inaccessible cavities of the human body for local active delivery of diagnostic and therapeutic agents. Active locomotion, targeting and steering of concentrated therape
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Universal portfolio algorithm

The universal portfolio algorithm is a portfolio selection algorithm from the field of machine learning and information theory. The algorithm learns adaptively from historical data and maximizes log-optimal growth rate in the long run, per the Kelly criterion. It was introduced by the late Stanford University information theorist Thomas M. Cover. The algorithm rebalances the portfolio at the beginning of each trading period. At the beginning of the first trading period it starts with a naive diversification. In the following trading periods the portfolio composition depends on the historical total return of all possible constant-rebalanced portfolios. The universal portfolio algorithm is the predecessor of the various online portfolio selection methodologies.
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Noisy text analytics

Noisy text analytics is a process of information extraction whose goal is to automatically extract structured or semistructured information from noisy unstructured text data. While Text analytics is a growing and mature field that has great value because of the huge amounts of data being produced, processing of noisy text is gaining in importance because a lot of common applications produce noisy text data. Noisy unstructured text data is found in informal settings such as online chat, text messages, e-mails, message boards, newsgroups, blogs, wikis and web pages. Also, text produced by processing spontaneous speech using automatic speech recognition and printed or handwritten text using optical character recognition contains processing noise. Text produced under such circumstances is typically highly noisy containing spelling errors, abbreviations, non-standard words, false starts, repetitions, missing punctuations, missing letter case information, pause filling words such as “um” and “uh” and other texting and speech disfluencies. Such text can be seen in large amounts in contact centers, chat rooms, optical character recognition (OCR) of text documents, short message service (SMS) text, etc. Documents with historical language can also be considered noisy with respect to today's knowledge about the language. Such text contains important historical, religious, ancient medical knowledge that is useful. The nature of the noisy text produced in all these contexts warrants moving beyond traditional text analysis techniques. == Techniques for noisy text analysis == Missing punctuation and the use of non-standard words can often hinder standard natural language processing tools such as part-of-speech tagging and parsing. Techniques to both learn from the noisy data and then to be able to process the noisy data are only now being developed. == Possible source of noisy text == World Wide Web: Poorly written text is found in web pages, online chat, blogs, wikis, discussion forums, newsgroups. Most of these data are unstructured and the style of writing is very different from, say, well-written news articles. Analysis for the web data is important because they are sources for market buzz analysis, market review, trend estimation, etc. Also, because of the large amount of data, it is necessary to find efficient methods of information extraction, classification, automatic summarization and analysis of these data. Contact centers: This is a general term for help desks, information lines and customer service centers operating in domains ranging from computer sales and support to mobile phones to apparels. On an average a person in the developed world interacts at least once a week with a contact center agent. A typical contact center agent handles over a hundred calls per day. They operate in various modes such as voice, online chat and E-mail. The contact center industry produces gigabytes of data in the form of E-mails, chat logs, voice conversation transcriptions, customer feedback, etc. A bulk of the contact center data is voice conversations. Transcription of these using state of the art automatic speech recognition results in text with 30-40% word error rate. Further, even written modes of communication like online chat between customers and agents and even the interactions over email tend to be noisy. Analysis of contact center data is essential for customer relationship management, customer satisfaction analysis, call modeling, customer profiling, agent profiling, etc., and it requires sophisticated techniques to handle poorly written text. Printed Documents: Many libraries, government organizations and national defence organizations have vast repositories of hard copy documents. To retrieve and process the content from such documents, they need to be processed using Optical Character Recognition. In addition to printed text, these documents may also contain handwritten annotations. OCRed text can be highly noisy depending on the font size, quality of the print etc. It can range from 2-3% word error rates to as high as 50-60% word error rates. Handwritten annotations can be particularly hard to decipher, and error rates can be quite high in their presence. Short Messaging Service (SMS): Language usage over computer mediated discourses, like chats, emails and SMS texts, significantly differs from the standard form of the language. An urge towards shorter message length facilitating faster typing and the need for semantic clarity, shape the structure of this non-standard form known as the texting language.
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Vector database

A vector database, vector store or vector search engine is a database that stores and retrieves embeddings of data in vector space. Vector databases typically implement approximate nearest neighbor algorithms so users can search for records semantically similar to a given input, unlike traditional databases which primarily look up records by exact match. Use-cases for vector databases include similarity search, semantic search, multi-modal search, recommendations engines, object detection, and retrieval-augmented generation (RAG). Vector embeddings are mathematical representations of data in a high-dimensional space. In this space, each dimension corresponds to a feature of the data, with the number of dimensions ranging from a few hundred to tens of thousands, depending on the complexity of the data being represented. Each data item is represented by one vector in this space. Words, phrases, or entire documents, as well as images, audio, and other types of data, can all be vectorized. These feature vectors may be computed from the raw data using machine learning methods such as feature extraction algorithms, word embeddings or deep learning networks. The goal is that semantically similar data items receive feature vectors close to each other. Vector retrieval can be combined with metadata filtering or lexical search to support filtered and hybrid retrieval workflows. == Techniques == Common techniques for similarity search on high-dimensional vectors include: Hierarchical Navigable Small World (HNSW) graphs Locality-sensitive hashing (LSH) and sketching Product quantization (PQ) Inverted files These techniques may also be combined in vector search systems. In recent benchmarks, HNSW-based implementations have been among the best performers. Conferences such as the International Conference on Similarity Search and Applications (SISAP) and the Conference on Neural Information Processing Systems (NeurIPS) have hosted competitions on vector search in large databases. == Applications == Vector databases are used in a wide range of machine learning applications including similarity search, semantic search, multi-modal search, recommendations engines, object detection, and retrieval-augmented generation. === Retrieval-augmented generation === An especially common use-case for vector databases is in retrieval-augmented generation (RAG), a method to improve domain-specific responses of large language models. The retrieval component of a RAG can be any search system, but is most often implemented as a vector database. Text documents describing the domain of interest are collected, and for each document or document section, a feature vector (known as an "embedding") is computed, typically using a deep learning network, and stored in a vector database along with a link to the document. Given a user prompt, the feature vector of the prompt is computed, and the database is queried to retrieve the most relevant documents. These are then automatically added into the context window of the large language model, and the large language model proceeds to create a response to the prompt given this context. == Implementations ==
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International Medical Education Directory

The International Medical Education Directory (IMED) was a public database of worldwide medical schools. The IMED was published as a joint collaboration of the Educational Commission for Foreign Medical Graduates (ECFMG) and the Foundation for Advancement of International Medical Education and Research (FAIMER). The information available in IMED was derived from data collected by the Educational Commission for Foreign Medical Graduates (ECFMG) throughout its history of evaluating the medical education credentials of international medical graduates. Using these data as a starting point, Foundation for Advancement of International Medical Education and Research (FAIMER) began developing IMED in 2001 and made it publicly available in April 2002. In April 2014, IMED was merged with the Avicenna Directory to create the World Directory of Medical Schools. The World Directory is now the definitive list of medical schools in the world, as IMED and Avicenna were discontinued in 2015.
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Neural field

In machine learning, a neural field (also known as implicit neural representation, neural implicit, or coordinate-based neural network), is a mathematical field that is fully or partially parametrized by a neural network. Initially developed to tackle visual computing tasks, such as rendering or reconstruction (e.g., neural radiance fields), neural fields emerged as a promising strategy to deal with a wider range of problems, including surrogate modelling of partial differential equations, such as in physics-informed neural networks. Differently from traditional machine learning algorithms, such as feed-forward neural networks, convolutional neural networks, or transformers, neural fields do not work with discrete data (e.g. sequences, images, tokens), but map continuous inputs (e.g., spatial coordinates, time) to continuous outputs (i.e., scalars, vectors, etc.). This makes neural fields not only discretization independent, but also easily differentiable. Moreover, dealing with continuous data allows for a significant reduction in space complexity, which translates to a much more lightweight network. == Formulation and training == According to the universal approximation theorem, provided adequate learning, sufficient number of hidden units, and the presence of a deterministic relationship between the input and the output, a neural network can approximate any function to any degree of accuracy. Hence, in mathematical terms, given a field y = Φ ( x ) {\textstyle {\boldsymbol {y}}=\Phi ({\boldsymbol {x}})} , with x ∈ R n {\displaystyle {\boldsymbol {x}}\in \mathbb {R} ^{n}} and y ∈ R m {\displaystyle {\boldsymbol {y}}\in \mathbb {R} ^{m}} , a neural field Ψ θ {\displaystyle \Psi _{\theta }} , with parameters θ {\displaystyle {\boldsymbol {\theta }}} , is such that: Ψ θ ( x ) = y ^ ≈ y {\displaystyle \Psi _{\theta }({\boldsymbol {x}})={\hat {\boldsymbol {y}}}\approx {\boldsymbol {y}}} === Training === For supervised tasks, given N {\displaystyle N} examples in the training dataset (i.e., ( x i , y i ) ∈ D t r a i n , i = 1 , … , N {\displaystyle ({\boldsymbol {x_{i}}},{\boldsymbol {y_{i}}})\in {\mathcal {D_{train}}},i=1,\dots ,N} ), the neural field parameters can be learned by minimizing a loss function L {\displaystyle {\mathcal {L}}} (e.g., mean squared error). The parameters θ ~ {\displaystyle {\tilde {\theta }}} that satisfy the optimization problem are found as: θ ~ = argmin θ 1 N ∑ ( x i , y i ) ∈ D t r a i n L ( Ψ θ ( x i ) , y i ) {\displaystyle {\tilde {\boldsymbol {\theta }}}={\underset {\boldsymbol {\theta }}{\text{argmin}}}\;{\frac {1}{N}}\sum _{({\boldsymbol {x_{i}}},{\boldsymbol {y_{i}}})\in {\mathcal {D_{train}}}}{\mathcal {L}}(\Psi _{\theta }({\boldsymbol {x}}_{i}),{\boldsymbol {y}}_{i})} Notably, it is not necessary to know the analytical expression of Φ {\displaystyle \Phi } , for the previously reported training procedure only requires input-output pairs. Indeed, a neural field is able to offer a continuous and differentiable surrogate of the true field, even from purely experimental data. Moreover, neural fields can be used in unsupervised settings, with training objectives that depend on the specific task. For example, physics-informed neural networks may be trained on just the residual. === Spectral bias === As for any artificial neural network, neural fields may be characterized by a spectral bias (i.e., the tendency to preferably learn the low frequency content of a field), possibly leading to a poor representation of the ground truth. In order to overcome this limitation, several strategies have been developed. For example, SIREN uses sinusoidal activations, while the Fourier-features approach embeds the input through sines and cosines. == Conditional neural fields == In many real-world cases, however, learning a single field is not enough. For example, when reconstructing 3D vehicle shapes from Lidar data, it is desirable to have a machine learning model that can work with arbitrary shapes (e.g., a car, a bicycle, a truck, etc.). The solution is to include additional parameters, the latent variables (or latent code) z ∈ R d {\displaystyle {\boldsymbol {z}}\in \mathbb {R} ^{d}} , to vary the field and adapt it to diverse tasks. === Latent code production === When dealing with conditional neural fields, the first design choice is represented by the way in which the latent code is produced. Specifically, two main strategies can be identified: Encoder: the latent code is the output of a second neural network, acting as an encoder. During training, the loss function is the objective used to learn the parameters of both the neural field and the encoder. Auto-decoding: each training example has its own latent code, jointly trained with the neural field parameters. When the model has to process new examples (i.e., not originally present in the training dataset), a small optimization problem is solved, keeping the network parameters fixed and only learning the new latent variables. Since the latter strategy requires additional optimization steps at inference time, it sacrifices speed, but keeps the overall model smaller. Moreover, despite being simpler to implement, an encoder may harm the generalization capabilities of the model. For example, when dealing with a physical scalar field f : R 2 → R {\displaystyle f:\mathbb {R} ^{2}\rightarrow \mathbb {R} } (e.g., the pressure of a 2D fluid), an auto-decoder-based conditional neural field can map a single point to the corresponding value of the field, following a learned latent code z {\displaystyle {\boldsymbol {z}}} . However, if the latent variables were produced by an encoder, it would require access to the entire set of points and corresponding values (e.g. as a regular grid or a mesh graph), leading to a less robust model. === Global and local conditioning === In a neural field with global conditioning, the latent code does not depend on the input and, hence, it offers a global representation (e.g., the overall shape of a vehicle). However, depending on the task, it may be more useful to divide the domain of x {\displaystyle {\boldsymbol {x}}} in several subdomains, and learn different latent codes for each of them (e.g., splitting a large and complex scene in sub-scenes for a more efficient rendering). This is called local conditioning. === Conditioning strategies === There are several strategies to include the conditioning information in the neural field. In the general mathematical framework, conditioning the neural field with the latent variables is equivalent to mapping them to a subset θ ∗ {\displaystyle {\boldsymbol {\theta }}^{}} of the neural field parameters: θ ∗ = Γ ( z ) {\displaystyle {\boldsymbol {\theta }}^{}=\Gamma ({\boldsymbol {z}})} In practice, notable strategies are: Concatenation: the neural field receives, as input, the concatenation of the original input x {\displaystyle {\boldsymbol {x}}} with the latent codes z {\displaystyle {\boldsymbol {z}}} . For feed-forward neural networks, this is equivalent to setting θ ∗ {\displaystyle {\boldsymbol {\theta }}^{}} as the bias of the first layer and Γ ( z ) {\displaystyle \Gamma ({\boldsymbol {z}})} as an affine transformation. Hypernetworks: a hypernetwork is a neural network that outputs the parameters of another neural network. Specifically, it consists of approximating Γ ( z ) {\displaystyle \Gamma ({\boldsymbol {z}})} with a neural network Γ ^ γ ( z ) {\displaystyle {\hat {\Gamma }}_{\gamma }({\boldsymbol {z}})} , where γ {\displaystyle {\boldsymbol {\gamma }}} are the trainable parameters of the hypernetwork. This approach is the most general, as it allows to learn the optimal mapping from latent codes to neural field parameters. However, hypernetworks are associated to larger computational and memory complexity, due to the large number of trainable parameters. Hence, leaner approaches have been developed. For example, in the Feature-wise Linear Modulation (FiLM), the hypernetwork only produces scale and bias coefficients for the neural field layers. === Meta-learning === Instead of relying on the latent code to adapt the neural field to a specific task, it is also possible to exploit gradient-based meta-learning. In this case, the neural field is seen as the specialization of an underlying meta-neural-field, whose parameters are modified to fit the specific task, through a few steps of gradient descent. An extension of this meta-learning framework is the CAVIA algorithm, that splits the trainable parameters in context-specific and shared groups, improving parallelization and interpretability, while reducing meta-overfitting. This strategy is similar to the auto-decoding conditional neural field, but the training procedure is substantially different. == Applications == Thanks to the possibility of efficiently modelling diverse mathematical fields with neural networks, neural fields have been applied to a wide range of problems: 3D scene reconstruction: neural fields can be used to model t
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Outline of natural language processing

Natural language processing is computer activity in which computers are entailed to analyze, understand, alter, or generate natural language. This includes the automation of any or all linguistic forms, activities, or methods of communication, such as conversation, correspondence, reading, written composition, dictation, publishing, translation, lip reading, and so on. Natural-language processing is also the name of the branch of computer science, artificial intelligence, and linguistics concerned with enabling computers to engage in communication using natural language(s) in all forms, including but not limited to speech, print, writing, and signing. The following outline is provided as an overview of and topical guide to natural-language processing: == Natural-language processing == Natural-language processing can be described as all of the following: A field of science – systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe. An applied science – field that applies human knowledge to build or design useful things. A field of computer science – scientific and practical approach to computation and its applications. A branch of artificial intelligence – intelligence of machines and robots and the branch of computer science that aims to create it. A subfield of computational linguistics – interdisciplinary field dealing with the statistical or rule-based modeling of natural language from a computational perspective. An application of engineering – science, skill, and profession of acquiring and applying scientific, economic, social, and practical knowledge, in order to design and also build structures, machines, devices, systems, materials and processes. An application of software engineering – application of a systematic, disciplined, quantifiable approach to the design, development, operation, and maintenance of software, and the study of these approaches; that is, the application of engineering to software. A subfield of computer programming – process of designing, writing, testing, debugging, and maintaining the source code of computer programs. This source code is written in one or more programming languages (such as Java, C++, C#, Python, etc.). The purpose of programming is to create a set of instructions that computers use to perform specific operations or to exhibit desired behaviors. A subfield of artificial intelligence programming – A type of system – set of interacting or interdependent components forming an integrated whole or a set of elements (often called 'components' ) and relationships which are different from relationships of the set or its elements to other elements or sets. A system that includes software – software is a collection of computer programs and related data that provides the instructions for telling a computer what to do and how to do it. Software refers to one or more computer programs and data held in the storage of the computer. In other words, software is a set of programs, procedures, algorithms and its documentation concerned with the operation of a data processing system. A type of technology – making, modification, usage, and knowledge of tools, machines, techniques, crafts, systems, methods of organization, in order to solve a problem, improve a preexisting solution to a problem, achieve a goal, handle an applied input/output relation or perform a specific function. It can also refer to the collection of such tools, machinery, modifications, arrangements and procedures. Technologies significantly affect human as well as other animal species' ability to control and adapt to their natural environments. A form of computer technology – computers and their application. NLP makes use of computers, image scanners, microphones, and many types of software programs. Language technology – consists of natural-language processing (NLP) and computational linguistics (CL) on the one hand, and speech technology on the other. It also includes many application oriented aspects of these. It is often called human language technology (HLT). == Prerequisite technologies == The following technologies make natural-language processing possible: Communication – the activity of a source sending a message to a receiver Language – Speech – Writing – Computing – Computers – Computer programming – Information extraction – User interface – Software – Text editing – program used to edit plain text files Word processing – piece of software used for composing, editing, formatting, printing documents Input devices – pieces of hardware for sending data to a computer to be processed Computer keyboard – typewriter style input device whose input is converted into various data depending on the circumstances Image scanners – == Subfields of natural-language processing == Information extraction (IE) – field concerned in general with the extraction of semantic information from text. This covers tasks such as named-entity recognition, coreference resolution, relationship extraction, etc. Ontology engineering – field that studies the methods and methodologies for building ontologies, which are formal representations of a set of concepts within a domain and the relationships between those concepts. Speech processing – field that covers speech recognition, text-to-speech and related tasks. Statistical natural-language processing – Statistical semantics – a subfield of computational semantics that establishes semantic relations between words to examine their contexts. Distributional semantics – a subfield of statistical semantics that examines the semantic relationship of words across a corpora or in large samples of data. == Related fields == Natural-language processing contributes to, and makes use of (the theories, tools, and methodologies from), the following fields: Automated reasoning – area of computer science and mathematical logic dedicated to understanding various aspects of reasoning, and producing software which allows computers to reason completely, or nearly completely, automatically. A sub-field of artificial intelligence, automatic reasoning is also grounded in theoretical computer science and philosophy of mind. Linguistics – scientific study of human language. Natural-language processing requires understanding of the structure and application of language, and therefore it draws heavily from linguistics. Applied linguistics – interdisciplinary field of study that identifies, investigates, and offers solutions to language-related real-life problems. Some of the academic fields related to applied linguistics are education, linguistics, psychology, computer science, anthropology, and sociology. Some of the subfields of applied linguistics relevant to natural-language processing are: Bilingualism / Multilingualism – Computer-mediated communication (CMC) – any communicative transaction that occurs through the use of two or more networked computers. Research on CMC focuses largely on the social effects of different computer-supported communication technologies. Many recent studies involve Internet-based social networking supported by social software. Contrastive linguistics – practice-oriented linguistic approach that seeks to describe the differences and similarities between a pair of languages. Conversation analysis (CA) – approach to the study of social interaction, embracing both verbal and non-verbal conduct, in situations of everyday life. Turn-taking is one aspect of language use that is studied by CA. Discourse analysis – various approaches to analyzing written, vocal, or sign language use or any significant semiotic event. Forensic linguistics – application of linguistic knowledge, methods and insights to the forensic context of law, language, crime investigation, trial, and judicial procedure. Interlinguistics – study of improving communications between people of different first languages with the use of ethnic and auxiliary languages (lingua franca). For instance by use of intentional international auxiliary languages, such as Esperanto or Interlingua, or spontaneous interlanguages known as pidgin languages. Language assessment – assessment of first, second or other language in the school, college, or university context; assessment of language use in the workplace; and assessment of language in the immigration, citizenship, and asylum contexts. The assessment may include analyses of listening, speaking, reading, writing or cultural understanding, with respect to understanding how the language works theoretically and the ability to use the language practically. Language pedagogy – science and art of language education, including approaches and methods of language teaching and study. Natural-language processing is used in programs designed to teach language, including first- and second-language training. Language planning – Language policy – Lexicography – Literacies – Pragmatics – Second-language acquisition – Stylistics – Translation – Comp
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Logical Machine Corporation

Logical Machine Corporation (LOMAC) was an American computer company active from the mid-1970s to the 1980s and based in the San Francisco Bay Area. It was founded as John Peers and Company by the British entrepreneur John Peers in 1974. LOMAC developed the ADAM, a minicomputer which ran a specialized compiler for the company's natural English programming language. Throughout the late 1970s, the company acquired several technology firms, including Byte, Inc., the owner of the Byte Shop retail chain. Despite its unique approach to computing and earning $5 million in revenue in 1977, LOMAC struggled as the industry began to standardize around the IBM Personal Computer (IBM PC). Following Peers's departure in 1980, the company rebranded as Logical Business Machines, Inc. (LBM, or simply Logical), and attempted to pivot toward IBM PC–compatible hardware. However, financial difficulties led to the company filing for Chapter 11 bankruptcy in 1984. After emerging from bankruptcy in 1985 with new investment, Logical ceased hardware manufacturing to focus exclusively on software development and value-added reselling. == History == John Peers (born 1942) founded Logical Machine Corporation as John Peers and Company in September 1974. The company originally occupied a 4,500-square-foot office in Burlingame, California. The company was Peers' fourth; he had recently sold off Allied Business Systems of London to Trafalgar House in 1974. Peers sought to set up manufacturing in an agricultural zone in Ukiah, California. Following a delay, caused in part by concerned residents, a 30,000-square-foot plant was raised in Burke Hill, three miles south of Ukiah. The Ukiah plant was built to mass manufacture the company's ADAM minicomputer. The ADAM computer ran a specialized compiler for the company's natural English programming language; that is to say, the programming language attempted to closely emulate English syntax. Prototypes of the ADAM were built in May 1974, based on specifications devised in October 1973. Peers had yet to patent the technology as of June 1975. The ADAM's central processing unit was bolted onto an 7-by-6-foot L-shaped desk, on which rested its terminal. Twenty units of the ADAM were installed between April 1975 and February 1976, out of a backlog of orders for 3,500 from 500 clients, manufactured out of the company's Burlingame headquarters. It cost US$40,000. A controversial print advertisement featuring a naked woman seated at an ADAM terminal—as a pastiche of Adam and Eve—was recalled in early 1976 as a result of outcry from the National Organization for Women. The company changed its name to Logical Machine Corporation (LOMAC) in October 1976 and moved its headquarters to a 26,000-square-foot building in Sunnyvale, California, in anticipation of a ramping up of orders for the ADAM. The company originally occupied half of the building; they later purchased the other half from the tenant in July 1977 to double its manufacturing output. For fiscal year 1977, the company earned $5 million in revenue. In December 1977, LOMAC acquired Byte, Inc.—the proprietor of The Byte Shop, the first computer retail chain—from Paul Terrell and Boyd Wilson for an unspecified amount. The Byte Shop had 65 locations in the San Francisco Bay Area in 1978; it catered mainly to hobbyists with low cost microcomputer kits, in contrast to the high cost of LOMAC's ADAM. By July 1978, however, LOMAC were able to reduce the price of the ADAM down to $15,000. The company by that point had shipped their 50th ADAM and expanded to 14 countries. Also in 1978, LOMAC acquired Mass Memory—a high-tech optical storage company based in Phoenix, Arizona, whose products had storage capacities on the order gigabytes and terabytes—and Centigram, makers of the Mike—a computer with speech recognition. Later that year, the company introduced Tina, a low-cost version of the ADAM. LOMAC suffered losses that year and appointed Jerry Brandt to the board of directions, naming him chief operating officer, in August 1978. Brandt had Logical absorb Mass Memory and Centigram into the parent operations, shutting down their respective plants in the process, converted 10 Byte Shops to franchises and opened 25 more franchised Byte locations, and stopped direct sales of LOMAC's business computer products. By the beginning of 1979, LOMAC was profitable once more, and Brandt was let go from LOMAC. Peers left LOMAC in 1980, following a slump in the company's sales. He became an executive director of the United States Robotics Society, a consortium for industrial automation companies, that year. Following Peers' departure, LOMAC changed its name to Logical Business Machines, adopting the name of its European subsidiary. In 1983, the company announced a 16-bit clone of the IBM PC, called the Logical L-XT, which featured a 10-MB hard drive, 320-KB floppy drive and 192 KB of RAM, and a real-time clock, and came shipped with various software (including MS-DOS, a word processor, and a spreadsheet application) and an amber CRT monitor. The following year, the company introduced L-NET, a local area network system based on the L-XT that could link up to 64 computers. L-NET came shipped with a natural programming language, Diplomat—a descendant of the programming language used on the ADAM. In June 1983, Logical sued Coleco Industries over trademark infringement with the latter's to-be-released Adam microcomputer. Logical cited confusion from their existing ADAM customer base caused by the announcement of the Coleco Adam as the basis for the suit. Coleco challenged Logical in the press, writing that Logical's rights to the Adam trademark for use in computers had lapsed earlier in the year. The two settled out of court, with Coleco agreeing to license the Adam name from Logical in exchange for unlimited rights to the Adam trademark. Logical halted development of the L-XT when they filed for Chapter 11 bankruptcy in July 1984. The company had been $4 million in debt. They emerged from bankruptcy in September 1985, after being infused with $2 million from Carat Ltd. The latter immediately received a little less than 50 percent ownership in Logical—this stake set to grow to over 50 percent over the next six months. As part of the terms of exiting bankruptcy, Logical stopped manufacturing hardware and strictly became a software development company and value-added reseller of computer systems.
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Pharmacy automation

Pharmacy automation involves the mechanical processes of handling and distributing medications. Any pharmacy task may be involved, including counting small objects (e.g., tablets, capsules); measuring and mixing powders and liquids for compounding; tracking and updating customer information in databases (e.g., personally identifiable information (PII), medical history, drug interaction risk detection); and inventory management. This article focuses on the changes that have taken place in the local, or community pharmacy since the 1960s. == History == Dispensing medications in a community pharmacy before the 1970s was a time-consuming operation. The pharmacist dispensed prescriptions in tablet or capsule form with a simple tray and spatula. Many new medications were developed by pharmaceutical manufacturers at an ever-increasing pace, and medications prices were rising steeply. A typical community pharmacist was working longer hours and often forced to hire staff to handle increased workloads which resulted in less time to focus on safety issues. These additional factors led to use of a machine to count medications. The original electronic portable digital tablet counting technology was invented in Manchester, England between 1967 and 1970 by the brothers John and Frank Kirby. I had the original idea of how the machine would work and it was my patent, but it was a joint effort getting it to work in a saleable form. It was 3 years of very hard work. I had originally studied heavy electrical engineering before changing over to Medical School and qualifying as a Medical Doctor in 1968. In fact I was Senior House (Casualty) Officer (A&E or ER) in 1970 at North Manchester General Hospital when I filed the patent. I must have been the only hospital doctor in Britain with an oscilloscope, a soldering iron and a drawing board in his room in the Doctors' Residence. The housekeepers were bemused by all the wires. Frank originally trained as a Banker but quit to take a job with a local electronics firm during the development. He died in 1987, a terrible loss. [Extract from personal communication received in March 2010 from John Kirby.] Frank and John Kirby and their associate Rodney Lester were pioneers in pharmacy automation and small-object counting technology. In 1967, the Kirbys invented a portable digital tablet counter to count tablets and capsules. With Lester they formed a limited company. In 1970, their invention was patented and put into production in Oldham, England. The tablet counter aided the pharmacy industry with time-consuming manual counting of drug prescriptions. A counting machine consistently counted medications accurately and quickly. This aspect of pharmacy automation was quickly adopted, and innovations emerged every decade to aid the pharmacy industry to deliver medications quickly, safely, and economically. Modern pharmacies have many new options to improve their workflow by using the new technology, and can choose intelligently from the many options available. === Chronology === On 1 January 1971 commercial production of the first portable digital tablet counters in the World began. John Kirby had filed U.K. Patent number GB1358378(A) on 8 September 1970 and U.S. patent number 3789194 on 9 August 1971. These early electronic counters were designed to help pharmacies replace the common (but often inaccurate) practice of counting medications by hand. In 1975, the digital technology was exported to America. In early 1980 a dedicated research, development and production facility was built in Oldham, England at a cost of £500,000. Between 1982 and 1983, two separate development facilities had been created. In America, overseen by Rodney Lester; and in England, overseen by the Kirby brothers. In 1987, Frank Kirby died. In 1989, John Kirby moved his UK facility to Devon, England. A simple to operate machine had been developed to accurately and quickly count prescription medications. Technology improvements soon resulted in a more compact model. The price of such equipment in 1980 was around £1,300. This substantial investment in new technology was a major financial consideration, but the pharmacy community considered the use of a counting machine as a superior method compared to hand-counting medications. These early devices became known as tablet counter, capsule counter, pill counter, or drug counter. The new counting technology replaced manual methods in many industries such as, vitamin and diet supplement manufacturing. Technicians needed a small, affordable device to count and bottle medications. In England and America, the 1980s and 1990s saw new the development of high-speed machines for counting and bottle filling, Like their pharmacy-based counterparts, these industrial units were designed to be fast and simple to operate, yet remain small and cost effective. In America, in the late 1990s/early 2000s a new type of tablet counter appeared. It was simple to use, compact, inexpensive, and had good counting accuracy. At the turn of the millennium technical advances allowed the design of counters with a software verification system. With an onboard computer, displaying photo images of medications to assist the pharmacist or pharmacy technician to verify that the correct medication was being dispensed. In addition, a database for storing all prescriptions that were counted on the device. Between September 2005 and May 2007, American Capital made a major financial investment in Kirby Lester, which then relocated to a larger facility to expand its research and development capabilities. This move added extra space for product research and development facility (R&D). It allowed the opportunity to develop new advanced technology products that met the pharmacy's needs for simple, accurate, and cost-effective ways to dispense prescriptions safely. Pictured here is an early American type of integrated counter and packaging device. This machine was a third generation step in the evolution of pharmacy automated devices. Later models held pre-counted containers of commonly-prescribed medications. == Global variations == In the EU member states legislation was introduced in 1998 which had a major effect on UK Pharmacy operations. It effectively prohibited the use of tablet counters for counting and dispensing bulk packaged tablets. Both usage and sales of the machines in the UK declined rapidly as a result of the introduction of blister packaging for medicines. == Current state of the industry == A tablet counter has become a standard in more than 30,000 sites in 35 countries (as of 2010) (including many non-pharmacy sites, such as manufacturing facilities that use a counting machine as a check for small items). During the 1990s through 2012, numerous new pharmacy automation products came to market. During this timeframe, counting technologies, robotics, workflow management software, and interactive voice recognition (IVR) systems for retail (both chain and independent), outpatient, government, and closed-door pharmacies (mail order and central fill) were all introduced. Additionally, the concept of scalability - of migrating from an entry-level product to the next level of automation (e.g., counting technology to robotics) - was introduced and subsequently launched a new product line in 1997. Pharmacists everywhere are making the switch to automation for its increased speed, greater accuracy, and better security. As the industry evolves and customer expectations grow, automation is becoming less of a luxury and more of a necessity. Especially for independent pharmacies, automation is now a means of keeping up with the competition of large chain pharmacies. == Technological changes and design improvements == Constant developments in technology make the dispensing of prescription medications safer, more accurate and more efficient. In America, in 2008, "next-generation" counting and verification systems were introduced. Based on the counting technology employed in preceding models, later machines included the ability to help the pharmacy operate more effectively. Equipped with a new computer interface to a pharmacy management system, with workflow and inventory software. It also included "checks and balances" to ensure the technician and pharmacist were dispensing the correct medication for each patient. This is something that is important to keep reported correctly when dealing with controlled substances like narcotics. This was a step forward to verify all 100% of prescriptions that were dispensed by pharmacy staff. In America, in 2009, further advanced counters were designed that included the ability to dispense hands-free – a feature that many operators had desired. This allowed pharmacies to automate their most commonly dispensed medications via calibrated cassettes. Thirty of a pharmacy's common medications would now be dispensed automatically. Another new model doubled that throughput via an enclosed robotic mechanism. Robo
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Gorn address

A Gorn address (Gorn, 1967) is a method of identifying and addressing any node within a tree data structure. This notation is often used for identifying nodes in a parse tree defined by phrase structure rules. The Gorn address is a sequence of zero or more integers conventionally separated by dots, e.g., 0 or 1.0.1. The root which Gorn calls can be regarded as the empty sequence. And the j {\displaystyle j} -th child of the i {\displaystyle i} -th child has an address i . j {\displaystyle i.j} , counting from 0. It is named after American computer scientist Saul Gorn.
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Semantic compression

In natural language processing, semantic compression is a process of compacting a lexicon used to build a textual document (or a set of documents) by reducing language heterogeneity, while maintaining text semantics. As a result, the same ideas can be represented using a smaller set of words. In most applications, semantic compression is a lossy compression. Increased prolixity does not compensate for the lexical compression and an original document cannot be reconstructed in a reverse process. == By generalization == Semantic compression is basically achieved in two steps, using frequency dictionaries and semantic network: determining cumulated term frequencies to identify target lexicon, replacing less frequent terms with their hypernyms (generalization) from target lexicon. Step 1 requires assembling word frequencies and information on semantic relationships, specifically hyponymy. Moving upwards in word hierarchy, a cumulative concept frequency is calculating by adding a sum of hyponyms' frequencies to frequency of their hypernym: c u m f ( k i ) = f ( k i ) + ∑ j c u m f ( k j ) {\displaystyle cumf(k_{i})=f(k_{i})+\sum _{j}cumf(k_{j})} where k i {\displaystyle k_{i}} is a hypernym of k j {\displaystyle k_{j}} . Then a desired number of words with top cumulated frequencies are chosen to build a target lexicon. In the second step, compression mapping rules are defined for the remaining words in order to handle every occurrence of a less frequent hyponym as its hypernym in output text. Example The below fragment of text has been processed by the semantic compression. Words in bold have been replaced by their hypernyms. They are both nest building social insects, but paper wasps and honey bees organize their colonies in very different ways. In a new study, researchers report that despite their differences, these insects rely on the same network of genes to guide their social behavior.The study appears in the Proceedings of the Royal Society B: Biological Sciences. Honey bees and paper wasps are separated by more than 100 million years of evolution, and there are striking differences in how they divvy up the work of maintaining a colony. The procedure outputs the following text: They are both facility building insect, but insects and honey insects arrange their biological groups in very different structure. In a new study, researchers report that despite their difference of opinions, these insects act the same network of genes to steer their party demeanor. The study appears in the proceeding of the institution bacteria Biological Sciences. Honey insects and insect are separated by more than hundred million years of organic processes, and there are impinging differences of opinions in how they divvy up the work of affirming a biological group. == Implicit semantic compression == A natural tendency to keep natural language expressions concise can be perceived as a form of implicit semantic compression, by omitting unmeaningful words or redundant meaningful words (especially to avoid pleonasms). == Applications and advantages == In the vector space model, compacting a lexicon leads to a reduction of dimensionality, which results in less computational complexity and a positive influence on efficiency. Semantic compression is advantageous in information retrieval tasks, improving their effectiveness (in terms of both precision and recall). This is due to more precise descriptors (reduced effect of language diversity – limited language redundancy, a step towards a controlled dictionary). As in the example above, it is possible to display the output as natural text (re-applying inflexion, adding stop words).
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ChromaDB

Chroma or ChromaDB is open-source data infrastructure tailored to applications with large language models. Its headquarters are in San Francisco. In April 2023, it raised 18 million US dollars as seed funding. ChromaDB has been used in academic studies on artificial intelligence, particularly as part of the tech stack for retrieval-augmented generation.
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Catie Cuan

Catie Cuan is an artist, entrepeuneur, and innovator in the field of robotic art and human-robot interaction, where she specializes in choreorobotics, an emerging field at the intersection of choreographic dance and robotics. Catie Cuan is currently one of the academic researchers pioneering the field of choreorobotics and currently holds a post-doctoral fellowship at Stanford University. == Career == Catie Cuan earned a bachelor's degree from the University of California, Berkeley. She graduated with a Ph.D. from the Department of Mechanical Engineering at Stanford University, focusing in robotics. Her most cited publication is about how to improve robotic expressive systems using tools from dance theory, such as the Laban/Bartenieff Movement Analysis. In her most recent research projects, she explores a predictive model of imitation learning for robots moving around humans, a project that advances the field of social robotics. Cuan credits her work in robotics to the experience with her father when he had a stroke and was surrounded by many medical machines, which made her think about how people might feel empowered and hopeful rather than afraid. As a ballet dancer and choreographer, she has performed with the Metropolitan Opera Ballet and the Lyric Opera of Chicago. In 2020, she was the dancer and choreographer of the show Output, which was part of a collaboration with ThoughtWorks Arts and the Pratt Institute. In the production, she danced with an ABB IRB 6700 industrial robot. In 2022, she was named as an IF/THEN ambassador for the American Association for the Advancement of Science. The same year, she was appointed Futurist-in-Residence at the Smithsonian Arts and Industries Building, where she performed at the closing ceremonies of the FUTURES exhibit on July 6, 2022. Cuan has also contributed to product designs, working with IDEO and Dutch interior design firm moooi on their Piro project, which launched a dancing scent diffuser robot during Milan Design Week in June 2022. She is a TED speaker with talks about how to teach robots to dance, and what is coming up for dancing robots in the AI era.
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Eyes of Things

Eyes of Things (EoT) is the name of a project funded by the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement number 643924. The purpose of the project, which is funded under the Smart Cyber-physical systems topic, is to develop a generic hardware-software platform for embedded, efficient (i.e. battery-operated, wearable, mobile), computer vision, including deep learning inference. On November 29, 2018, the European Space Agency announced that it was testing the suitability of the device for space applications in advance of a flight in a Cubesat. == Motivation == EoT is based on the following tenets: Future embedded systems will have more intelligence and cognitive functionality. Vision is paramount to such intelligent capacity Unlike other sensors, vision requires intensive processing. Power consumption must be optimized if vision is to be used in mobile and wearable applications Cloud processing of edge-captured images is not sustainable. The sheer amount of visual data generated cannot be transferred to the cloud. Bandwidth is not sufficient and cloud servers cannot cope with it. == Partners == VISILAB group at University of Castilla–La Mancha (Coordinator) Movidius Awaiba Thales Security Solutions & Systems DFKI Fluxguide Evercam nVISO == Awards == 2019 Electronic Component and Systems Innovation Award by the European Commission 2018 HiPEAC Tech Transfer Award 2018 EC Innovation Radar - highlighting excellent innovations Award 2018 Internet of Things (IoT) Technology Research Award Pilot by Google 2016 Semifinalist "THE VISION SHOW STARTUP COMPETITION", Global Association for Vision Information, Boston US
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Verbot

The Verbot (short for Verbal-Robot) was a chatbot program and artificial intelligence software development kit (SDK) designed for Windows and web platforms. == Early beginning == The origin of verbot traces back to Michael Mauldin's research during his time as a graduate student and post-doctoral fellow at Carnegie Mellon University. The creative foundation also stems from Peter Plantec's work in personality psychology and art direction. === Historic outline === In 1994, Michael Loren Mauldin, founder of Lycos, Inc., developed a prototype chatbot, Julia, which competed in the internationally known Turing test, for the coveted Loebner Prize. The Turing test matches computer scientist judges against machines to see if they can distinguish a computer from a real human. Julia was refined and developed, and in 1997, Dr. Mauldin and Peter Plantec, a clinical psychologist and animator, formed Virtual Personalities, Inc. (now Conversive, Inc.) in order to create a virtual human interface that would incorporate real-time animation as well as speech and natural language processing. The initial release, a stand-alone virtual person called Sylvie, was beta-tested to the public. This release was well received, and finally, after several versions, the production release (deemed version 3) of the Verbally Enhanced Software Robot, or Verbot, was deployed in fall 2000. The grandfather of all Verbots is Rog-O-Matic, which, although it could not talk, could and did explore a virtual world. Julia has been active on the internet in one form or another since 1989. A close cousin of Julia is Lycos, a robot that explores the World Wide Web and answers questions about it. Sylvie was the first Verbot with a face and a voice. Sylvie was the first Virtual Human with advanced, flexible interfacing capability. === Beginnings === The Virtual Personalities story goes back to 1978, where Mauldin was attending Rice University. Fascinated by the idea of ELIZA, he proceeded to write a program called "PET" for his 8 kilobyte Commodore PET Computer. PET included simple induction as a way to post new information, for example: Subject: I like my friend (later) Subject: I like food. PET: I have heard that food is your friend. Meanwhile, Plantec was separately designing a personality for "Entity", a theoretical virtual human that would interact comfortably with humans without pretending to be one. At that time the technology was not advanced enough to realize Entity. Mauldin got so involved with this that he majored in Computer Science and minored in Linguistics. === Rogue === In the late seventies and early eighties, a popular computer game at universities was Rogue, an implementation of Dungeons and Dragons where the player would descend 26 levels in a randomly created dungeon, fighting monsters, gathering treasure, and searching for the elusive "Amulet of Yendor". Mauldin was one of four grad students who devoted a large amount of time to building a program called "Rog-O-Matic" capable of retrieving the amulet and emerging victorious from the dungeon. === TinyMUD === In 1989, when James Aspnes at Carnegie Mellon created the first TinyMUD (a descendant of MUD and AberMUD), Mauldin was one of the first to create a computer player that would explore the text-based world of TinyMUD. But his first robot, Gloria, gradually accreted more and more linguistic ability, to the point that it could pass the "unsuspecting" Turing test. In this version of the test, the human has no reason to suspect that one of the other occupants of the room is controlled by a computer, and so is more polite and asks fewer probing questions. The second generation of Mauldin's TinyMUD robots was Julia, created on Jan. 8, 1990. Julia slowly developed into a more and more capable conversational agent, and assumed useful duties in the TinyMUD world, including tour guide, information assistant, note-taker, and message-relayer. She could even play the card game hearts along with the other human players. In 1991, Julia attended the first Loebner Prize contest in Boston, Massachusetts. Although she only finished third, she was ranked by one judge as more human than one of the human confederates, winning a coveted certificate of humanness in the world's first restricted Turing test. Julia continued to log in to various TinyMUD's and TinyMucks for the next seven years, and chatted with hundreds of people a month over the internet. === Lycos === Julia's job was to explore a virtual world consisting of pages of textual descriptions, with links between them, and to construct an internal map of that world and answer questions about it (including path information such as the shortest route from one room to another, and matching information, such as which rooms contained a certain kind of object or textual description). It was therefore only a very short cognitive leap from Julia to Lycos, another robotic agent that explores a virtual world made of hyperlinked pages of text, and which answers questions about those pages. Sylvie was born and her abilities were expanded greatly to include interfacing with computers and control systems via her serial ports. === Sylvie === Sylvie was the first intelligent animated virtual human. She was designed both as a conversation agent and as a virtual human interface that would form a bridge between the two. She became more popular as a conversation agent, but her designers believe she serves as a prototype for future virtual human interface design that will help us all cope with the increasing complexity of technology. As an aside, Plantec noticed that a large number of Sylvies have been sold in Southeast Asia. Upon investigation, he found out that students had discovered a "test" mode that would allow them to type in English sentences that Sylvie would pronounce in her somewhat stylized English. == Ownership == In 1997, Dr. Mauldin and Peter Plantec formed Virtual Personalities, Inc. to create Natural Language Processing solutions for companies. In 2001 Virtual Personalities, Inc. became Conversive, Inc. to reflect the focus on providing Customer Service and Marketing to the Enterprise Market. In late 2012 Avaya, Inc. acquired Conversive's assets including Verbots. == Verbot versions == The Verbot 4 version was created and released in 2004. In 2005 Version 4.1 of the Verbot Software was released with many feature enhancements and bug fixes, including built-in support for embedding C# code in outputs and conditionals. In early 2006 Conversive launched Verbots Online allowing Verbot 4 users to upload their knowledge and show off their bots to the world. In 2009 Version 5 was released, completely free and fully featured. In early 2012 the last version of Verbot, 5.0.1.2, was released to the general public with support for Windows 7. Later in 2012 Verbots Online completely shut down. == Verbots today == Verbots.com, its community of users, and its forums no longer exist, but the software and users can still be found. There has been no active development since the early 2012 release of Verbot 5.0.1.2.
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