Trying to pick the best AI sales assistant? An AI sales assistant is software that uses machine learning to help you get more done — it scales effortlessly from a single task to thousands. The best picks balance beginner-friendly simplicity with the depth power users need, and they ship updates often. Whether you are a beginner or a pro, the right AI sales assistant slots into your workflow and pays for itself fast. Read on for hands-on impressions, pricing tiers, and the standout features that matter.
D/Vision Pro
D/Vision Pro was one of the earliest marketed non-linear editing systems. It was released by TouchVision Systems, Inc. in the mid-1990s. The program was DOS-based and worked on either Intel's 386 or 486 processor. The system used AVI compression and worked with the Action Media II board. The system allowed users to digitize video, audio, and timecode, create an edit decision list (EDL), instantly play back the edited program, and output the finished EDL in a wide variety of formats. These cost-effective editing systems were used by numerous independent filmmakers and in low-budget productions during the mid-late 1990s. D/Vision Pro's low-quality compression led TouchVision (later renamed D/Vision Systems) to abandon it in favor of D/Vision Online, which was purchased by Discreet Logic and renamed edit. In June 2002, Discreet discontinued edit, as they did not want it to interfere with smoke sales which were more profitable. Discreet was later purchased by Autodesk.
Cancer Likelihood in Plasma
Cancer Likelihood in Plasma (CLiP) refers to a set of ensemble learning methods for integrating various genomic features useful for the noninvasive detection of early cancers from blood plasma. An application of this technique for early detection of lung cancer (Lung-CLiP) was originally described by Chabon et al. (2020) from the labs of Ash Alizadeh and Max Diehn at Stanford. This method relies on several improvements to cancer personalized profiling by deep sequencing (CAPP-Seq) for analysis of circulating tumor DNA (ctDNA). The CLiP technique integrates multiple distinctive genomic features of a cancer of interest findings within a machine-learning framework for cancer detection. For example, studies have shown that the majority of somatic mutations found in cell-free DNA (cfDNA) are not tumor derived, but instead reflect clonal hematopoeisis (also known as CHIP). Even though CHIP tends to target specific genes, it also involves many generally non-recurrent mutations that can be shed from leukocytes and detected in cfDNA, regardless of whether profiling patients with cancer and healthy adults. However, genuine tumor derived ctDNA mutations can be distinguished from CHIP-derived mutations. This is because unlike tumor-derived mutations, CHIP-derived mutations that are shed from leukocytes into plasma tend to occur on longer cfDNA fragments, and to lack specific mutational signatures such as those associated with tobacco smoking in lung cancer that are also found in tumor derived ctDNA molecules. CLiP integrates these features within hierarchical ensemble machine learning models that consider somatic mutations and copy number alternations, among other features. While the CLiP method is unique in relying exclusively on mutations and copy number alterations, it is related to a variety of other liquid biopsy methods being commercially developed for early cancer detection using ctDNA and proteins (e.g., CancerSEEK / DETECT-A ), cfDNA fragmentation patterns (e.g., DELFI), and DNA methylation (e.g., cfMeDIP-Seq, Grail). While the CLiP method has not yet been broadly applied for population-based cancer screening, it has been shown to distinguish discriminate early-stage lung cancers from risk-matched controls across multiple cohorts of patients enrolled across the US.
Spatial computing
Spatial computing refers to 3D human–computer interaction techniques that are perceived by users as taking place in the real world, in and around their bodies and physical environments, instead of constrained to and perceptually behind computer screens or in purely virtual worlds. This concept inverts the long-standing practice of teaching people to interact with computers in digital environments, and instead teaches computers to better understand and interact with people more naturally in the human world. This concept overlaps with and encompasses others including extended reality, augmented reality, mixed reality, natural user interface, contextual computing, affective computing, and ubiquitous computing. The usage for labeling and discussing these adjacent technologies is imprecise. Spatial computing devices include sensors—such as RGB cameras, depth cameras, 3D trackers, inertial measurement units, or other tools—to sense and track nearby human bodies (including hands, arms, eyes, legs, mouths) during ordinary interactions with people and computers in a 3D space. They further use computer vision to attempt to understand real world scenes, such as rooms, streets or stores, to read labels, to recognize objects, create 3D maps, and more. Quite often they also use extended reality and mixed reality to superimpose virtual 3D graphics and virtual 3D audio onto the human visual and auditory system as a way of providing information more naturally and contextually than traditional 2D screens. Spatial computing often refers to personal computing devices like headsets and headphones, but other human-computer interactions that leverage real-time spatial positioning for displays, like projection mapping or cave automatic virtual environment displays, can also be considered spatial computing if they leverage human-computer input for the participants. == History == The term "spatial computing" apparently originated in the field of GIS around 1985 or earlier to describe computations on large-scale geospatial information. Early examples of spatial computing in GIS include ArcInfo and its iterations, initially released in 1981, a part of ArcGIS along with ArcEditor, which together provide mapping, analysis, editing, and geoprocessing for geodatabases. This is somewhat related to the modern use, but on the scale of continents, cities, and neighborhoods. Modern spatial computing is more centered on the human scale of interaction, around the size of a living room or smaller. But it is not limited to that scale in the aggregate. In the early 1990s, as field of virtual reality was beginning to be commercialized beyond academic and military labs, a startup called Worldesign in Seattle used the term Spatial Computing to describe the interaction between individual people and 3D spaces, operating more at the human end of the scale than previous GIS examples may have contemplated. The company built a CAVE-like environment it called the Virtual Environment Theater, whose 3D experience was of a virtual flyover of the Giza Plateau, circa 3000 BC. Robert Jacobson, CEO of Worldesign, attributes the origins of the term to experiments at the Human Interface Technology Lab, at the University of Washington, under the direction of Thomas A. Furness III. Jacobson was a co-founder of that lab before spinning off this early VR startup. In 1997, an academic publication by T. Caelli, Peng Lam, and H. Bunke called "Spatial Computing: Issues in Vision, Multimedia and Visualization Technologies" introduced the term more broadly for academic audiences, focusing on a variety of topics such as image processing, dead reckoning navigation, object recognition, and visualizing spatial data. The specific term "spatial computing" was later referenced again in 2003 by Simon Greenwold, as "human interaction with a machine in which the machine retains and manipulates referents to real objects and spaces". MIT Media Lab alumnus John Underkoffler gave a TED talk in 2010 giving a live demo of the multi-screen, multi-user spatial computing systems being developed by Oblong Industries, which sought to bring to life the futuristic interfaces conceptualized by Underkoffler in the films Minority Report and Iron Man. Google Earth, initially released by Keyhole Inc. in 2001 and re-released by Google in 2005 can be considered a capable GIS and includes advanced geospatial tools and capabilities. == Notable instances of the use of spatial computing == In 2019, Microsoft HoloLens released a video outlining Airbus' partnership with Microsoft Azure to utilize the latter's mixed reality services for streamlining and improving the aircraft design process, as well as reducing the error in development. Airbus utilized the HoloLens 2 to this end, and the executive vice president of engineering claimed that their design process' validation phases were "hugely accelerated by 80 percent", as well as "strongly believe[d]" that up to 30% improvements in their industrial tasks could be attained with the HoloLens 2. During the presentational video, Airbus cited the maturity of Microsoft Azure services as "key" for their usage of the HoloLens 2. Also in 2019, the U.S. army partnered with Microsoft to produce a HoloLens based Integrated Visual Augmentation System (IVAS) to enhance infantry members by giving troops various abilities, including but not limited to using holographs to train, projecting 3D maps into their vision, and seeing through smoke and corners. Microsoft received tens of thousands of hours of feedback for their systems by 2021. Sergeant Marc Krugh at the time claimed that Microsoft's partnership has already caused the army to rethink some of its troops' operation strategy. == Products == === Apple Vision Pro === Apple announced Apple Vision Pro, a device it markets as a "spatial computer", on June 5, 2023. It includes several features such as Spatial Audio, two 4K micro-OLED displays, the Apple R1 chip and eye tracking, and released in the United States on February 2, 2024. In announcing the platform, Apple invoked its history of popularizing 2D graphical user interfaces that supplanted prior human-computer interface mechanisms such as the command line. Apple suggests the introduction of spatial computing as a new category of interactive device, on the same level of importance as the introduction of the 2D GUI. Apple Vision Pro runs on a new operating system called visionOS, which combines eye tracking, gesture recognition, and voice input to enable immersive interaction without physical controllers. The platform is aimed at productivity, entertainment, collaboration, and enterprise use cases. === Magic Leap === Magic Leap had also previously used the term “spatial computing” to describe its own devices. Its first headset, the Magic Leap 1, was released on August 8, 2018. Magic Leap’s technology enables the display of content into the real world using an optical see-through head-mounted display, which projects an overlay of a virtual world into the user’s field of view. This allows for an experience where the physical and digital worlds are perceived simultaneously. === Microsoft Hololens === On February 24, 2019, Microsoft released the HoloLens 2, which includes mixed reality tools and can generate interactable, manipulatable holograms in 3D space. The holograms in question can be related to a physical object or completely independent and free-floating. The Azure Spatial Anchors cloud service was released simultaneously, which gives the holograms capability to persist across time and many individuals' devices. === Meta Quest === The Meta Quest 3, a mixed reality gaming headset that includes spatial audio, two color cameras, and grants the ability to interact with virtual characters released on October 9, 2023, at a notably cheaper price than the Apple Vision Pro, but with reduced capabilities. === Snap Spectacles === Spectacles (product) are augmented reality glasses developed by Snap Inc.. The latest generation includes a 46-degree stereoscopic display, adjustable tint, and Snapdragon processors. Spectacles allow users to interact with a collection of augmented reality experiences designed for education, entertainment, and utility. Currently, the device is in the hands of selected developers and creators, as part of an experimental AR ecosystem focused on creativity, use case exploration and expression.
Algorithmic Puzzles
Algorithmic Puzzles is a book of puzzles based on computational thinking. It was written by computer scientists Anany and Maria Levitin, and published in 2011 by Oxford University Press. == Topics == The book begins with a "tutorial" introducing classical algorithm design techniques including backtracking, divide-and-conquer algorithms, and dynamic programming, methods for the analysis of algorithms, and their application in example puzzles. The puzzles themselves are grouped into three sets of 50 puzzles, in increasing order of difficulty. A final two chapters provide brief hints and more detailed solutions to the puzzles, with the solutions forming the majority of pages of the book. Some of the puzzles are well known classics, some are variations of known puzzles making them more algorithmic, and some are new. They include: Puzzles involving chessboards, including the eight queens puzzle, knight's tours, and the mutilated chessboard problem Balance puzzles River crossing puzzles The Tower of Hanoi Finding the missing element in a data stream The geometric median problem for Manhattan distance == Audience and reception == The puzzles in the book cover a wide range of difficulty, and in general do not require more than a high school level of mathematical background. William Gasarch notes that grouping the puzzles only by their difficulty and not by their themes is actually an advantage, as it provides readers with fewer clues about their solutions. Reviewer Narayanan Narayanan recommends the book to any puzzle aficionado, or to anyone who wants to develop their powers of algorithmic thinking. Reviewer Martin Griffiths suggests another group of readers, schoolteachers and university instructors in search of examples to illustrate the power of algorithmic thinking. Gasarch recommends the book to any computer scientist, evaluating it as "a delight".
Nobody (username)
In many Unix variants, "nobody" is the conventional name of a user identifier which owns no files, is in no privileged groups, and has no abilities except those which every other user has. It is normally not enabled as a user account, i.e. has no home directory or login credentials assigned. Some systems also define an equivalent group "nogroup". == Uses == The pseudo-user "nobody" and group "nogroup" are used, for example, in the NFSv4 implementation of Linux by idmapd, if a user or group name in an incoming packet does not match any known username on the system. It was once common to run daemons as nobody, especially on servers, in order to limit the damage that could be done by a malicious user who gained control of them. However, the usefulness of this technique is reduced if more than one daemon is run like this, because then gaining control of one daemon would provide control of them all. The reason is that processes owned by the same user have the ability to send signals to each other and use debugging facilities to read or even modify each other's memory. Modern practice, as recommended by the Linux Standard Base, is to create a separate user account for each daemon.
Bisection (software engineering)
Bisection is a method used in software development to identify change sets that result in a specific behavior change. It is mostly employed for finding the patch that introduced a bug. Another application area is finding the patch that indirectly fixed a bug. == Overview == The process of locating the changeset that introduced a specific regression was described as "source change isolation" in 1997 by Brian Ness and Viet Ngo of Cray Research. Regression testing was performed on Cray's compilers in editions comprising one or more changesets. Editions with known regressions could not be validated until developers addressed the problem. Source change isolation narrowed the cause to a single changeset that could then be excluded from editions, unblocking them with respect to this problem, while the author of the change worked on a fix. Ness and Ngo outlined linear search and binary search methods of performing this isolation. Code bisection has the goal of minimizing the effort to find a specific change set. It employs a divide and conquer algorithm that depends on having access to the code history which is usually preserved by revision control in a code repository. == Bisection method == === Code bisection algorithm === Code history has the structure of a directed acyclic graph which can be topologically sorted. This makes it possible to use a divide and conquer search algorithm which: splits up the search space of candidate revisions tests for the behavior in question reduces the search space depending on the test result re-iterates the steps above until a range with at most one bisectable patch candidate remains === Algorithmic complexity === Bisection is in LSPACE having an algorithmic complexity of O ( log N ) {\displaystyle O(\log N)} with N {\displaystyle N} denoting the number of revisions in the search space, and is similar to a binary search. === Desirable repository properties === For code bisection it is desirable that each revision in the search space can be built and tested independently. === Monotonicity === For the bisection algorithm to identify a single changeset which caused the behavior being tested to change, the behavior must change monotonically across the search space. For a Boolean function such as a pass/fail test, this means that it only changes once across all changesets between the start and end of the search space. If there are multiple changesets across the search space where the behavior being tested changes between false and true, then the bisection algorithm will find one of them, but it will not necessarily be the root cause of the change in behavior between the start and the end of the search space. The root cause could be a different changeset, or a combination of two or more changesets across the search space. To help deal with this problem, automated tools allow specific changesets to be ignored during a bisection search. == Automation support == Although the bisection method can be completed manually, one of its main advantages is that it can be easily automated. It can thus fit into existing test automation processes: failures in exhaustive automated regression tests can trigger automated bisection to localize faults. Ness and Ngo focused on its potential in Cray's continuous delivery-style environment in which the automatically isolated bad changeset could be automatically excluded from builds. The revision control systems Fossil, Git and Mercurial have built-in functionality for code bisection. The user can start a bisection session with a specified range of revisions from which the revision control system proposes a revision to test, the user tells the system whether the revision tested as "good" or "bad", and the process repeats until the specific "bad" revision has been identified. Other revision control systems, such as Bazaar or Subversion, support bisection through plugins or external scripts. Phoronix Test Suite can do bisection automatically to find performance regressions.