Image registration

Image registration

Image registration is the process of transforming different sets of data into one coordinate system. Data may be multiple photographs, data from different sensors, times, depths, or viewpoints. It is used in computer vision, medical imaging, military automatic target recognition, and compiling and analyzing images and data from satellites. Registration is necessary in order to be able to compare or integrate the data obtained from these different measurements. == Algorithm classification == === Intensity-based vs feature-based === Image registration or image alignment algorithms can be classified into intensity-based and feature-based. One of the images is referred to as the target, fixed or sensed image and the others are referred to as the moving or source images. Image registration involves spatially transforming the source/moving image(s) to align with the target image. The reference frame in the target image is stationary, while the other datasets are transformed to match to the target. Intensity-based methods compare intensity patterns in images via correlation metrics, while feature-based methods find correspondence between image features such as points, lines, and contours. Intensity-based methods register entire images or sub-images. If sub-images are registered, centers of corresponding sub images are treated as corresponding feature points. Feature-based methods establish a correspondence between a number of especially distinct points in images. Knowing the correspondence between a number of points in images, a geometrical transformation is then determined to map the target image to the reference images, thereby establishing point-by-point correspondence between the reference and target images. Methods combining intensity-based and feature-based information have also been developed. === Transformation models === Image registration algorithms can also be classified according to the transformation models they use to relate the target image space to the reference image space. The first broad category of transformation models includes affine transformations, which include rotation, scaling, translation and shearing. Affine transformations are global in nature, thus, they cannot model local geometric differences between images. The second category of transformations allow 'elastic' or 'nonrigid' transformations. These transformations are capable of locally warping the target image to align with the reference image. Nonrigid transformations include radial basis functions (thin-plate or surface splines, multiquadrics, and compactly-supported transformations), physical continuum models (viscous fluids), and large deformation models (diffeomorphisms). Transformations are commonly described by a parametrization, where the model dictates the number of parameters. For instance, the translation of a full image can be described by a translation vector parameter. These models are called parametric models. Non-parametric models on the other hand, do not follow any parameterization, allowing each image element to be displaced arbitrarily. There are a number of programs that implement both estimation and application of a warp-field. It is a part of the SPM and AIR programs. === Transformations of coordinates via the law of function composition rather than addition === Alternatively, many advanced methods for spatial normalization are building on structure preserving transformations homeomorphisms and diffeomorphisms since they carry smooth submanifolds smoothly during transformation. Diffeomorphisms are generated in the modern field of Computational Anatomy based on flows since diffeomorphisms are not additive although they form a group, but a group under the law of function composition. For this reason, flows which generalize the ideas of additive groups allow for generating large deformations that preserve topology, providing 1-1 and onto transformations. Computational methods for generating such transformation are often called LDDMM which provide flows of diffeomorphisms as the main computational tool for connecting coordinate systems corresponding to the geodesic flows of Computational Anatomy. There are a number of programs which generate diffeomorphic transformations of coordinates via diffeomorphic mapping including MRI Studio and MRI Cloud.org === Spatial vs frequency domain methods === Spatial methods operate in the image domain, matching intensity patterns or features in images. Some of the feature matching algorithms are outgrowths of traditional techniques for performing manual image registration, in which an operator chooses corresponding control points (CP) in images. When the number of control points exceeds the minimum required to define the appropriate transformation model, iterative algorithms like RANSAC can be used to robustly estimate the parameters of a particular transformation type (e.g. affine) for registration of the images. Frequency-domain methods find the transformation parameters for registration of the images while working in the transform domain. Such methods work for simple transformations, such as translation, rotation, and scaling. Applying the phase correlation method to a pair of images produces a third image which contains a single peak. The location of this peak corresponds to the relative translation between the images. Unlike many spatial-domain algorithms, the phase correlation method is resilient to noise, occlusions, and other defects typical of medical or satellite images. Additionally, the phase correlation uses the fast Fourier transform to compute the cross-correlation between the two images, generally resulting in large performance gains. The method can be extended to determine rotation and scaling differences between two images by first converting the images to log-polar coordinates. Due to properties of the Fourier transform, the rotation and scaling parameters can be determined in a manner invariant to translation. === Single- vs multi-modality methods === Another classification can be made between single-modality and multi-modality methods. Single-modality methods tend to register images in the same modality acquired by the same scanner/sensor type, while multi-modality registration methods tended to register images acquired by different scanner/sensor types. Multi-modality registration methods are often used in medical imaging as images of a subject are frequently obtained from different scanners. Examples include registration of brain CT/MRI images or whole body PET/CT images for tumor localization, registration of contrast-enhanced CT images against non-contrast-enhanced CT images for segmentation of specific parts of the anatomy, and registration of ultrasound and CT images for prostate localization in radiotherapy. === Automatic vs interactive methods === Registration methods may be classified based on the level of automation they provide. Manual, interactive, semi-automatic, and automatic methods have been developed. Manual methods provide tools to align the images manually. Interactive methods reduce user bias by performing certain key operations automatically while still relying on the user to guide the registration. Semi-automatic methods perform more of the registration steps automatically but depend on the user to verify the correctness of a registration. Automatic methods do not allow any user interaction and perform all registration steps automatically. === Similarity measures for image registration === Image similarities are broadly used in medical imaging. An image similarity measure quantifies the degree of similarity between intensity patterns in two images. The choice of an image similarity measure depends on the modality of the images to be registered. Common examples of image similarity measures include cross-correlation, mutual information, sum of squared intensity differences, and ratio image uniformity. Mutual information and normalized mutual information are the most popular image similarity measures for registration of multimodality images. Cross-correlation, sum of squared intensity differences and ratio image uniformity are commonly used for registration of images in the same modality. Many new features have been derived for cost functions based on matching methods via large deformations have emerged in the field Computational Anatomy including Measure matching which are pointsets or landmarks without correspondence, Curve matching and Surface matching via mathematical currents and varifolds. == Uncertainty == There is a level of uncertainty associated with registering images that have any spatio-temporal differences. A confident registration with a measure of uncertainty is critical for many change detection applications such as medical diagnostics. In remote sensing applications where a digital image pixel may represent several kilometers of spatial distance (such as NASA's LANDSAT imagery), an uncertain image registration can mean that a solution could b

Feature engineering

Feature engineering is a preprocessing step in supervised machine learning and statistical modeling which transforms raw data into a more effective set of inputs. Each input comprises several attributes, known as features. By providing models with relevant information, feature engineering significantly enhances their predictive accuracy and decision-making capability. Beyond machine learning, the principles of feature engineering are applied in various scientific fields, including physics. For example, physicists construct dimensionless numbers such as the Reynolds number in fluid dynamics, the Nusselt number in heat transfer, and the Archimedes number in sedimentation. They also develop first approximations of solutions, such as analytical solutions for the strength of materials in mechanics. == Clustering == One of the applications of feature engineering has been clustering of feature-objects or sample-objects in a dataset. Especially, feature engineering based on matrix decomposition has been extensively used for data clustering under non-negativity constraints on the feature coefficients. These include Non-Negative Matrix Factorization (NMF), Non-Negative Matrix-Tri Factorization (NMTF), Non-Negative Tensor Decomposition/Factorization (NTF/NTD), etc. The non-negativity constraints on coefficients of the feature vectors mined by the above-stated algorithms yields a part-based representation, and different factor matrices exhibit natural clustering properties. Several extensions of the above-stated feature engineering methods have been reported in literature, including orthogonality-constrained factorization for hard clustering, and manifold learning to overcome inherent issues with these algorithms. Other classes of feature engineering algorithms include leveraging a common hidden structure across multiple inter-related datasets to obtain a consensus (common) clustering scheme. An example is Multi-view Classification based on Consensus Matrix Decomposition (MCMD), which mines a common clustering scheme across multiple datasets. MCMD is designed to output two types of class labels (scale-variant and scale-invariant clustering), and: is computationally robust to missing information, can obtain shape- and scale-based outliers, and can handle high-dimensional data effectively. Coupled matrix and tensor decompositions are popular in multi-view feature engineering. == Predictive modelling == Feature engineering in machine learning and statistical modeling involves selecting, creating, transforming, and extracting data features. Key components include feature creation from existing data, transforming and imputing missing or invalid features, reducing data dimensionality through methods like Principal Components Analysis (PCA), Independent Component Analysis (ICA), and Linear Discriminant Analysis (LDA), and selecting the most relevant features for model training based on importance scores and correlation matrices. Features vary in significance. Even relatively insignificant features may contribute to a model. Feature selection can reduce the number of features to prevent a model from becoming too specific to the training data set (overfitting). Feature explosion occurs when the number of identified features is too large for effective model estimation or optimization. Common causes include: Feature templates - implementing feature templates instead of coding new features Feature combinations - combinations that cannot be represented by a linear system Feature explosion can be limited via techniques such as regularization, kernel methods, and feature selection. == Automation == Automation of feature engineering is a research topic that dates back to the 1990s. Machine learning software that incorporates automated feature engineering has been commercially available since 2016. Related academic literature can be roughly separated into two types: Multi-relational Decision Tree Learning (MRDTL) uses a supervised algorithm that is similar to a decision tree. Deep Feature Synthesis uses simpler methods. === Multi-relational Decision Tree Learning (MRDTL) === Multi-relational Decision Tree Learning (MRDTL) extends traditional decision tree methods to relational databases, handling complex data relationships across tables. It innovatively uses selection graphs as decision nodes, refined systematically until a specific termination criterion is reached. Most MRDTL studies base implementations on relational databases, which results in many redundant operations. These redundancies can be reduced by using techniques such as tuple id propagation. === Open-source implementations === There are a number of open-source libraries and tools that automate feature engineering on relational data and time series: featuretools is a Python library for transforming time series and relational data into feature matrices for machine learning. MCMD: An open-source feature engineering algorithm for joint clustering of multiple datasets. OneBM or One-Button Machine combines feature transformations and feature selection on relational data with feature selection techniques. OneBM helps data scientists reduce data exploration time allowing them to try and error many ideas in short time. On the other hand, it enables non-experts, who are not familiar with data science, to quickly extract value from their data with a little effort, time, and cost. getML community is an open source tool for automated feature engineering on time series and relational data. It is implemented in C/C++ with a Python interface. It has been shown to be at least 60 times faster than tsflex, tsfresh, tsfel, featuretools or kats. tsfresh is a Python library for feature extraction on time series data. It evaluates the quality of the features using hypothesis testing. tsflex is an open source Python library for extracting features from time series data. Despite being 100% written in Python, it has been shown to be faster and more memory efficient than tsfresh, seglearn or tsfel. seglearn is an extension for multivariate, sequential time series data to the scikit-learn Python library. tsfel is a Python package for feature extraction on time series data. kats is a Python toolkit for analyzing time series data. === Deep feature synthesis === The deep feature synthesis (DFS) algorithm beat 615 of 906 human teams in a competition. == Feature stores == The feature store is where the features are stored and organized for the explicit purpose of being used to either train models (by data scientists) or make predictions (by applications that have a trained model). It is a central location where you can either create or update groups of features created from multiple different data sources, or create and update new datasets from those feature groups for training models or for use in applications that do not want to compute the features but just retrieve them when it needs them to make predictions. A feature store includes the ability to store code used to generate features, apply the code to raw data, and serve those features to models upon request. Useful capabilities include feature versioning and policies governing the circumstances under which features can be used. Feature stores can be standalone software tools or built into machine learning platforms. == Alternatives == Feature engineering can be a time-consuming and error-prone process, as it requires domain expertise and often involves trial and error. Deep learning algorithms may be used to process a large raw dataset without having to resort to feature engineering. However, deep learning algorithms still require careful preprocessing and cleaning of the input data. In addition, choosing the right architecture, hyperparameters, and optimization algorithm for a deep neural network can be a challenging and iterative process.

Speculative decoding

Speculative decoding is an inference-time optimization for autoregressive large language models (LLMs) that generates multiple tokens per decoding step instead of one. A smaller draft model proposes a sequence of candidate tokens, and the larger target model verifies them in a single forward pass through a modified rejection sampling scheme. The verification preserves the target model's original output distribution, so the technique produces the same results as standard decoding while cutting latency by roughly two to three times. The name is an analogy to speculative execution in CPU design, where a processor runs instructions along a predicted branch before the outcome is known. == Background == Standard autoregressive decoding in large language models generates one token at a time. The model computes a probability distribution over its vocabulary, samples the next token, and feeds that token back as input. For large models, this process is bottlenecked by memory bandwidth rather than arithmetic throughput: loading the model's parameters from high-bandwidth memory (HBM) to the processor takes up most of the wall-clock time at each step. Because of this, a forward pass over one token and a forward pass over several tokens in a batch take roughly the same time. Speculative decoding relies on this property. == Mechanism == The technique alternates between two phases: drafting and verification. During drafting, a fast approximation model generates a short run of K candidate tokens, typically between 3 and 12. The draft model is usually a much smaller version of the target model or a lightweight auxiliary network. During verification, the target model scores the entire draft sequence in one batched forward pass. A modified rejection sampling algorithm compares the draft and target probabilities at each position. If the target model would have been at least as likely to produce a given token, that token is accepted; the first token that fails is resampled from a corrected distribution, and everything after it is thrown out. The result is that the output distribution is the same as if each token had been generated one at a time. How many tokens get accepted per cycle depends on how well the draft model matches the target. For common words and predictable continuations the match tends to be good, so the target model can confirm several tokens at once. == History == An early precursor was blockwise parallel decoding, proposed in 2018 by Stern, Shazeer, and Uszkoreit. Their method predicted multiple future tokens through auxiliary prediction heads and validated them against the autoregressive model, but it only worked with greedy decoding and did not preserve the full sampling distribution. The modern form of the technique came from Yaniv Leviathan, Matan Kalman, and Yossi Matias at Google Research, who posted "Fast Inference from Transformers via Speculative Decoding" on arXiv in November 2022. Separately and at about the same time, Charlie Chen and colleagues at DeepMind arrived at a closely related method they called speculative sampling, published in February 2023. Both papers introduced the use of rejection sampling to guarantee that the output distribution is unchanged. Leviathan et al. showed roughly 2–3x speedup on T5-XXL (11 billion parameters); Chen et al. reported 2–2.5x on the Chinchilla model (70 billion parameters). The Leviathan et al. paper was presented as an oral at the International Conference on Machine Learning in July 2023. == Variants == SpecInfer (Miao et al., 2024) uses multiple small language models to jointly build a tree of candidate continuations rather than a single chain. The target model verifies the whole tree in parallel and keeps the longest valid path, with reported speedups of 1.5–3.5x. Medusa (Cai et al., 2024) takes a different approach by not using a separate draft model at all. Extra lightweight decoding heads are attached to the target model itself, and each one predicts a token at a different future position. The candidates are evaluated through a tree-structured attention mechanism. The authors measured 2.2–3.6x speedup. EAGLE (Li et al., 2024) performs autoregression on the target model's internal feature representations (specifically the second-to-top layer) rather than on tokens directly. On LLaMA 2 Chat 70B, this gave a 2.7–3.5x latency reduction. Later versions added dynamic draft trees (EAGLE-2) and further optimizations (EAGLE-3), reaching 3–6.5x speedup. == Adoption == By 2024, speculative decoding had become a standard part of production LLM serving. Google uses it in the AI Overviews feature of Google Search. Open-source inference frameworks such as vLLM, NVIDIA's TensorRT-LLM, and SGLang all include built-in support for speculative decoding and its variants. Apple, AWS, and Meta have also published research extending the method or deploying it at scale.

SGT STAR

SGT STAR, also known as Sgt. Star or Sergeant Star, was a chatbot operated by the United States Army to answer questions about recruitment. == Background == After the September 11 attacks, traffic increased significantly to chatrooms on the U.S. Army's website, goarmy.com, increasing costs of staffing the live chatrooms. As a cost-cutting measure, the SGT STAR project was initiated as a partnership between the United States Army Accessions Command and Spectre AI, a wholly owned subsidiary of Next IT. Next IT, a Spokane, Washington-based company deploys "intelligent virtual assistants," using its software dubbed "ActiveAgent" which is a framework for functional presence engines. Testing began in 2003, and SGT STAR launched to the public in 2006. "STAR" is an acronym for "strong, trained and ready." SGT STAR was launched as a chat interface on goarmy.com, but has since been developed as a mobile application, as well as a life-size animated projection that has appeared live at public events. SGT STAR can also interact with users on Facebook. == FOIA request == In 2013, the Electronic Frontier Foundation filed a Freedom of Information Act request to learn more about SGT STAR, including input and output patterns (questions and answers), usage statistics, contracts, and privacy policies. They received these records in April 2014, after coverage from various media outlets and a tongue-in-cheek campaign to "Free Sgt. Star."

1.58-bit large language model

A 1.58-bit large language model (also known as a ternary LLM) is a type of large language model (LLM) designed to be computationally efficient. It achieves this by using weights that are restricted to only three values: -1, 0, and +1. This restriction significantly reduces the model's memory footprint and allows for faster processing, as computationally expensive multiplication operations can be replaced with lower-cost additions. This contrasts with traditional models that use 16-bit floating-point numbers (FP16 or BF16) for their weights. Studies have shown that for models up to several billion parameters, the performance of 1.58-bit LLMs on various tasks is comparable to their full-precision counterparts. This approach could enable powerful AI to run on less specialized and lower-power hardware. The name "1.58-bit" comes from the fact that a system with three states contains log 2 ⁡ 3 ≈ 1.58 {\displaystyle \log _{2}3\approx 1.58} bits of information. These models are sometimes also referred to as 1-bit LLMs in research papers, although this term can also refer to true binary models (with weights of -1 and +1). == BitNet == In 2024, Ma et al., researchers at Microsoft, declared that their 1.58-bit model, BitNet b1.58 is comparable in performance to the 16-bit Llama 2 and opens the era of 1-bit LLM. BitNet creators did not use the post-training quantization of weights but instead relied on the new BitLinear transform that replaced the nn.Linear layer of the traditional transformer design. In 2025, Microsoft researchers had released an open-weights and open inference code model BitNet b1.58 2B4T demonstrating performance competitive with the full precision models at 2B parameters and 4T training tokens. == Post-training quantization == BitNet derives its performance from being trained natively in 1.58 bit instead of being quantized from a full-precision model after training. Still, training is an expensive process and it would be desirable to be able to somehow convert an existing model to 1.58 bits. In 2024, HuggingFace reported a way to gradually ramp up the 1.58-bit quantization in fine-tuning an existing model down to 1.58 bits. == Critique == Some researchers point out that the scaling laws of large language models favor the low-bit weights only in case of undertrained models. As the number of training tokens increases, the deficiencies of low-bit quantization surface.

Pharmacy automation

Pharmacy automation involves the mechanical processes of handling and distributing medications. Any pharmacy task may be involved, including counting small objects (e.g., tablets, capsules); measuring and mixing powders and liquids for compounding; tracking and updating customer information in databases (e.g., personally identifiable information (PII), medical history, drug interaction risk detection); and inventory management. This article focuses on the changes that have taken place in the local, or community pharmacy since the 1960s. == History == Dispensing medications in a community pharmacy before the 1970s was a time-consuming operation. The pharmacist dispensed prescriptions in tablet or capsule form with a simple tray and spatula. Many new medications were developed by pharmaceutical manufacturers at an ever-increasing pace, and medications prices were rising steeply. A typical community pharmacist was working longer hours and often forced to hire staff to handle increased workloads which resulted in less time to focus on safety issues. These additional factors led to use of a machine to count medications. The original electronic portable digital tablet counting technology was invented in Manchester, England between 1967 and 1970 by the brothers John and Frank Kirby. I had the original idea of how the machine would work and it was my patent, but it was a joint effort getting it to work in a saleable form. It was 3 years of very hard work. I had originally studied heavy electrical engineering before changing over to Medical School and qualifying as a Medical Doctor in 1968. In fact I was Senior House (Casualty) Officer (A&E or ER) in 1970 at North Manchester General Hospital when I filed the patent. I must have been the only hospital doctor in Britain with an oscilloscope, a soldering iron and a drawing board in his room in the Doctors' Residence. The housekeepers were bemused by all the wires. Frank originally trained as a Banker but quit to take a job with a local electronics firm during the development. He died in 1987, a terrible loss. [Extract from personal communication received in March 2010 from John Kirby.] Frank and John Kirby and their associate Rodney Lester were pioneers in pharmacy automation and small-object counting technology. In 1967, the Kirbys invented a portable digital tablet counter to count tablets and capsules. With Lester they formed a limited company. In 1970, their invention was patented and put into production in Oldham, England. The tablet counter aided the pharmacy industry with time-consuming manual counting of drug prescriptions. A counting machine consistently counted medications accurately and quickly. This aspect of pharmacy automation was quickly adopted, and innovations emerged every decade to aid the pharmacy industry to deliver medications quickly, safely, and economically. Modern pharmacies have many new options to improve their workflow by using the new technology, and can choose intelligently from the many options available. === Chronology === On 1 January 1971 commercial production of the first portable digital tablet counters in the World began. John Kirby had filed U.K. Patent number GB1358378(A) on 8 September 1970 and U.S. patent number 3789194 on 9 August 1971. These early electronic counters were designed to help pharmacies replace the common (but often inaccurate) practice of counting medications by hand. In 1975, the digital technology was exported to America. In early 1980 a dedicated research, development and production facility was built in Oldham, England at a cost of £500,000. Between 1982 and 1983, two separate development facilities had been created. In America, overseen by Rodney Lester; and in England, overseen by the Kirby brothers. In 1987, Frank Kirby died. In 1989, John Kirby moved his UK facility to Devon, England. A simple to operate machine had been developed to accurately and quickly count prescription medications. Technology improvements soon resulted in a more compact model. The price of such equipment in 1980 was around £1,300. This substantial investment in new technology was a major financial consideration, but the pharmacy community considered the use of a counting machine as a superior method compared to hand-counting medications. These early devices became known as tablet counter, capsule counter, pill counter, or drug counter. The new counting technology replaced manual methods in many industries such as, vitamin and diet supplement manufacturing. Technicians needed a small, affordable device to count and bottle medications. In England and America, the 1980s and 1990s saw new the development of high-speed machines for counting and bottle filling, Like their pharmacy-based counterparts, these industrial units were designed to be fast and simple to operate, yet remain small and cost effective. In America, in the late 1990s/early 2000s a new type of tablet counter appeared. It was simple to use, compact, inexpensive, and had good counting accuracy. At the turn of the millennium technical advances allowed the design of counters with a software verification system. With an onboard computer, displaying photo images of medications to assist the pharmacist or pharmacy technician to verify that the correct medication was being dispensed. In addition, a database for storing all prescriptions that were counted on the device. Between September 2005 and May 2007, American Capital made a major financial investment in Kirby Lester, which then relocated to a larger facility to expand its research and development capabilities. This move added extra space for product research and development facility (R&D). It allowed the opportunity to develop new advanced technology products that met the pharmacy's needs for simple, accurate, and cost-effective ways to dispense prescriptions safely. Pictured here is an early American type of integrated counter and packaging device. This machine was a third generation step in the evolution of pharmacy automated devices. Later models held pre-counted containers of commonly-prescribed medications. == Global variations == In the EU member states legislation was introduced in 1998 which had a major effect on UK Pharmacy operations. It effectively prohibited the use of tablet counters for counting and dispensing bulk packaged tablets. Both usage and sales of the machines in the UK declined rapidly as a result of the introduction of blister packaging for medicines. == Current state of the industry == A tablet counter has become a standard in more than 30,000 sites in 35 countries (as of 2010) (including many non-pharmacy sites, such as manufacturing facilities that use a counting machine as a check for small items). During the 1990s through 2012, numerous new pharmacy automation products came to market. During this timeframe, counting technologies, robotics, workflow management software, and interactive voice recognition (IVR) systems for retail (both chain and independent), outpatient, government, and closed-door pharmacies (mail order and central fill) were all introduced. Additionally, the concept of scalability - of migrating from an entry-level product to the next level of automation (e.g., counting technology to robotics) - was introduced and subsequently launched a new product line in 1997. Pharmacists everywhere are making the switch to automation for its increased speed, greater accuracy, and better security. As the industry evolves and customer expectations grow, automation is becoming less of a luxury and more of a necessity. Especially for independent pharmacies, automation is now a means of keeping up with the competition of large chain pharmacies. == Technological changes and design improvements == Constant developments in technology make the dispensing of prescription medications safer, more accurate and more efficient. In America, in 2008, "next-generation" counting and verification systems were introduced. Based on the counting technology employed in preceding models, later machines included the ability to help the pharmacy operate more effectively. Equipped with a new computer interface to a pharmacy management system, with workflow and inventory software. It also included "checks and balances" to ensure the technician and pharmacist were dispensing the correct medication for each patient. This is something that is important to keep reported correctly when dealing with controlled substances like narcotics. This was a step forward to verify all 100% of prescriptions that were dispensed by pharmacy staff. In America, in 2009, further advanced counters were designed that included the ability to dispense hands-free – a feature that many operators had desired. This allowed pharmacies to automate their most commonly dispensed medications via calibrated cassettes. Thirty of a pharmacy's common medications would now be dispensed automatically. Another new model doubled that throughput via an enclosed robotic mechanism. Robo

BERT (language model)

Bidirectional encoder representations from transformers (BERT) is a language model introduced in October 2018 by researchers at Google. It learns to represent text as a sequence of vectors using self-supervised learning. It uses the encoder-only transformer architecture. BERT dramatically improved the state of the art for large language models. As of 2020, BERT is a ubiquitous baseline in natural language processing (NLP) experiments. BERT is trained by masked token prediction and next sentence prediction. With this training, BERT learns contextual, latent representations of tokens in their context, similar to ELMo and GPT-2. It found applications for many natural language processing tasks, such as coreference resolution and polysemy resolution. It improved on ELMo and spawned the study of "BERTology", which attempts to interpret what is learned by BERT. BERT was originally implemented in the English language at two model sizes, BERTBASE (110 million parameters) and BERTLARGE (340 million parameters). Both were trained on the Toronto BookCorpus (800M words) and English Wikipedia (2,500M words). The weights were released on GitHub. On March 11, 2020, 24 smaller models were released, the smallest being BERTTINY with just 4 million parameters. == Architecture == BERT is an "encoder-only" transformer architecture. At a high level, BERT consists of 4 modules: Tokenizer: This module converts a piece of English text into a sequence of integers ("tokens"). Embedding: This module converts the sequence of tokens into an array of real-valued vectors representing the tokens. It represents the conversion of discrete token types into a lower-dimensional Euclidean space. Encoder: a stack of Transformer blocks with self-attention, but without causal masking. Task head: This module converts the final representation vectors into one-shot encoded tokens again by producing a predicted probability distribution over the token types. It can be viewed as a simple decoder, decoding the latent representation into token types, or as an "un-embedding layer". The task head is necessary for pre-training, but it is often unnecessary for so-called "downstream tasks," such as question answering or sentiment classification. Instead, one removes the task head and replaces it with a newly initialized module suited for the task, and finetune the new module. The latent vector representation of the model is directly fed into this new module, allowing for sample-efficient transfer learning. === Embedding === This section describes the embedding used by BERTBASE. The other one, BERTLARGE, is similar, just larger. The tokenizer of BERT is WordPiece, which is a sub-word strategy like byte-pair encoding. Its vocabulary size is 30,000, and any token not appearing in its vocabulary is replaced by [UNK] ("unknown"). The first layer is the embedding layer, which contains three components: token type embeddings, position embeddings, and segment type embeddings. Token type: The token type is a standard embedding layer, translating a one-hot vector into a dense vector based on its token type. Position: The position embeddings are based on a token's position in the sequence. BERT uses absolute position embeddings, where each position in a sequence is mapped to a real-valued vector. Each dimension of the vector consists of a sinusoidal function that takes the position in the sequence as input. Segment type: Using a vocabulary of just 0 or 1, this embedding layer produces a dense vector based on whether the token belongs to the first or second text segment in that input. In other words, type-1 tokens are all tokens that appear after the [SEP] special token. All prior tokens are type-0. The three embedding vectors are added together representing the initial token representation as a function of these three pieces of information. After embedding, the vector representation is normalized using a LayerNorm operation, outputting a 768-dimensional vector for each input token. After this, the representation vectors are passed forward through 12 Transformer encoder blocks, and are decoded back to 30,000-dimensional vocabulary space using a basic affine transformation layer. === Architectural family === The encoder stack of BERT has 2 free parameters: L {\displaystyle L} , the number of layers, and H {\displaystyle H} , the hidden size. There are always H / 64 {\displaystyle H/64} self-attention heads, and the feed-forward/filter size is always 4 H {\displaystyle 4H} . By varying these two numbers, one obtains an entire family of BERT models. For BERT: the feed-forward size and filter size are synonymous. Both of them denote the number of dimensions in the middle layer of the feed-forward network. the hidden size and embedding size are synonymous. Both of them denote the number of real numbers used to represent a token. The notation for encoder stack is written as L/H. For example, BERTBASE is written as 12L/768H, BERTLARGE as 24L/1024H, and BERTTINY as 2L/128H. == Training == === Pre-training === BERT was pre-trained simultaneously on two tasks: Masked language modeling (MLM): In this task, BERT ingests a sequence of words, where one word may be randomly changed ("masked"), and BERT tries to predict the original words that had been changed. For example, in the sentence "The cat sat on the [MASK]," BERT would need to predict "mat." This helps BERT learn bidirectional context, meaning it understands the relationships between words not just from left to right or right to left but from both directions at the same time. Next sentence prediction (NSP): In this task, BERT is trained to predict whether one sentence logically follows another. For example, given two sentences, "The cat sat on the mat" and "It was a sunny day", BERT has to decide if the second sentence is a valid continuation of the first one. This helps BERT understand relationships between sentences, which is important for tasks like question answering or document classification. ==== Masked language modeling ==== In masked language modeling, 15% of tokens would be randomly selected for masked-prediction task, and the training objective was to predict the masked token given its context. In more detail, the selected token is: replaced with a [MASK] token with probability 80%, replaced with a random word token with probability 10%, not replaced with probability 10%. The reason not all selected tokens are masked is to avoid the dataset shift problem. The dataset shift problem arises when the distribution of inputs seen during training differs significantly from the distribution encountered during inference. A trained BERT model might be applied to word representation (like Word2Vec), where it would be run over sentences not containing any [MASK] tokens. It is later found that more diverse training objectives are generally better. As an illustrative example, consider the sentence "my dog is cute". It would first be divided into tokens like "my1 dog2 is3 cute4". Then a random token in the sentence would be picked. Let it be the 4th one "cute4". Next, there would be three possibilities: with probability 80%, the chosen token is masked, resulting in "my1 dog2 is3 [MASK]4"; with probability 10%, the chosen token is replaced by a uniformly sampled random token, such as "happy", resulting in "my1 dog2 is3 happy4"; with probability 10%, nothing is done, resulting in "my1 dog2 is3 cute4". After processing the input text, the model's 4th output vector is passed to its decoder layer, which outputs a probability distribution over its 30,000-dimensional vocabulary space. ==== Next sentence prediction ==== Given two sentences, the model predicts if they appear sequentially in the training corpus, outputting either [IsNext] or [NotNext]. During training, the algorithm sometimes samples two sentences from a single continuous span in the training corpus, while at other times, it samples two sentences from two discontinuous spans. The first sentence starts with a special token, [CLS] (for "classify"). The two sentences are separated by another special token, [SEP] (for "separate"). After processing the two sentences, the final vector for the [CLS] token is passed to a linear layer for binary classification into [IsNext] and [NotNext]. For example: Given "[CLS] my dog is cute [SEP] he likes playing [SEP]", the model should predict [IsNext]. Given "[CLS] my dog is cute [SEP] how do magnets work [SEP]", the model should predict [NotNext]. === Fine-tuning === BERT is meant as a general pretrained model for various applications in natural language processing. That is, after pre-training, BERT can be fine-tuned with fewer resources on smaller datasets to optimize its performance on specific tasks such as natural language inference and text classification, and sequence-to-sequence-based language generation tasks such as question answering and conversational response generation. The original BERT paper published results demonstrating that a small amount of fine