U-Net

U-Net

U-Net is a convolutional neural network that was developed for image segmentation. The network is based on a fully convolutional neural network whose architecture was modified and extended to work with fewer training images and to yield more precise segmentation. Segmentation of a 512 × 512 image takes less than a second on a modern (2015) GPU using the U-Net architecture. The U-Net architecture has also been employed in diffusion models for iterative image denoising. This technology underlies many modern image generation models, such as DALL-E, Midjourney, and Stable Diffusion. U-Net is also being explored for language models. Tokenization is not a separate step, allowing the model to more easily understand spelling and concurrently vectorizing / tokenizing higher level concepts. == Description == The U-Net architecture stems from the so-called "fully convolutional network". The main idea is to supplement a usual contracting network by successive layers, where pooling operations are replaced by upsampling operators. Hence these layers increase the resolution of the output. A successive convolutional layer can then learn to assemble a precise output based on this information. One important modification in U-Net is that there are a large number of feature channels in the upsampling part, which allow the network to propagate context information to higher resolution layers. As a consequence, the expansive path is more or less symmetric to the contracting part, and yields a u-shaped architecture. The network only uses the valid part of each convolution without any fully connected layers. To predict the pixels in the border region of the image, the missing context is extrapolated by mirroring the input image. This tiling strategy is important to apply the network to large images, since otherwise the resolution would be limited by the GPU memory. Recently, there had also been an interest in receptive field based U-Net models for medical image segmentation. == Network architecture == The network consists of a contracting path and an expansive path, which gives it the u-shaped architecture. The contracting path is a typical convolutional network that consists of repeated application of convolutions, each followed by a rectified linear unit (ReLU) and a max pooling operation. During the contraction, the spatial information is reduced while feature information is increased. The expansive pathway combines the feature and spatial information through a sequence of up-convolutions and concatenations with high-resolution features from the contracting path. == Applications == There are many applications of U-Net in biomedical image segmentation, such as brain image segmentation (''BRATS'') and liver image segmentation ("siliver07") as well as protein binding site prediction. U-Net implementations have also found use in the physical sciences, for example in the analysis of micrographs of materials. Variations of the U-Net have also been applied for medical image reconstruction. Here are some variants and applications of U-Net as follows: Pixel-wise regression using U-Net and its application on pansharpening; 3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation; TernausNet: U-Net with VGG11 Encoder Pre-Trained on ImageNet for Image Segmentation. Image-to-image translation to estimate fluorescent stains In binding site prediction of protein structure. == History == U-Net was created by Olaf Ronneberger, Philipp Fischer, Thomas Brox in 2015 and reported in the paper "U-Net: Convolutional Networks for Biomedical Image Segmentation". It is an improvement and development of FCN: Evan Shelhamer, Jonathan Long, Trevor Darrell (2014). "Fully convolutional networks for semantic segmentation".

Hyperparameter optimization

In machine learning, hyperparameter optimization or tuning is the problem of choosing a set of optimal hyperparameters for a learning algorithm. A hyperparameter is a parameter whose value is used to control the learning process, which must be configured before the process starts. Hyperparameter optimization determines the set of hyperparameters that yields an optimal model which minimizes a predefined loss function on a given data set. The objective function takes a set of hyperparameters and returns the associated loss. Cross-validation is often used to estimate this generalization performance, and therefore choose the set of values for hyperparameters that maximize it. == Approaches == === Grid search === The traditional method for hyperparameter optimization has been grid search, or a parameter sweep, which is simply an exhaustive searching through a manually specified subset of the hyperparameter space of a learning algorithm. A grid search algorithm must be guided by some performance metric, typically measured by cross-validation on the training set or evaluation on a hold-out validation set. Since the parameter space of a machine learner may include real-valued or unbounded value spaces for certain parameters, manually set bounds and discretization may be necessary before applying grid search. For example, a typical soft-margin SVM classifier equipped with an RBF kernel has at least two hyperparameters that need to be tuned for good performance on unseen data: a regularization constant C and a kernel hyperparameter γ. Both parameters are continuous, so to perform grid search, one selects a finite set of "reasonable" values for each, say C ∈ { 10 , 100 , 1000 } {\displaystyle C\in \{10,100,1000\}} γ ∈ { 0.1 , 0.2 , 0.5 , 1.0 } {\displaystyle \gamma \in \{0.1,0.2,0.5,1.0\}} Grid search then trains an SVM with each pair (C, γ) in the Cartesian product of these two sets and evaluates their performance on a held-out validation set (or by internal cross-validation on the training set, in which case multiple SVMs are trained per pair). Finally, the grid search algorithm outputs the settings that achieved the highest score in the validation procedure. Grid search suffers from the curse of dimensionality, but is often embarrassingly parallel because the hyperparameter settings it evaluates are typically independent of each other. === Random search === Random Search replaces the exhaustive enumeration of all combinations by selecting them randomly. This can be simply applied to the discrete setting described above, but also generalizes to continuous and mixed spaces. A benefit over grid search is that random search can explore many more values than grid search could for continuous hyperparameters. It can outperform Grid search, especially when only a small number of hyperparameters affects the final performance of the machine learning algorithm. In this case, the optimization problem is said to have a low intrinsic dimensionality. Random Search is also embarrassingly parallel, and additionally allows the inclusion of prior knowledge by specifying the distribution from which to sample. Despite its simplicity, random search remains one of the important base-lines against which to compare the performance of new hyperparameter optimization methods. === Bayesian optimization === Bayesian optimization is a global optimization method for noisy black-box functions. Applied to hyperparameter optimization, Bayesian optimization builds a probabilistic model of the function mapping from hyperparameter values to the objective evaluated on a validation set. By iteratively evaluating a promising hyperparameter configuration based on the current model, and then updating it, Bayesian optimization aims to gather observations revealing as much information as possible about this function and, in particular, the location of the optimum. It tries to balance exploration (hyperparameters for which the outcome is most uncertain) and exploitation (hyperparameters expected close to the optimum). In practice, Bayesian optimization has been shown to obtain better results in fewer evaluations compared to grid search and random search, due to the ability to reason about the quality of experiments before they are run. === Gradient-based optimization === For specific learning algorithms, it is possible to compute the gradient with respect to hyperparameters and then optimize the hyperparameters using gradient descent. The first usage of these techniques was focused on neural networks. Since then, these methods have been extended to other models such as support vector machines or logistic regression. A different approach in order to obtain a gradient with respect to hyperparameters consists in differentiating the steps of an iterative optimization algorithm using automatic differentiation. A more recent work along this direction uses the implicit function theorem to calculate hypergradients and proposes a stable approximation of the inverse Hessian. The method scales to millions of hyperparameters and requires constant memory. In a different approach, a hypernetwork is trained to approximate the best response function. One of the advantages of this method is that it can handle discrete hyperparameters as well. Self-tuning networks offer a memory efficient version of this approach by choosing a compact representation for the hypernetwork. More recently, Δ-STN has improved this method further by a slight reparameterization of the hypernetwork which speeds up training. Δ-STN also yields a better approximation of the best-response Jacobian by linearizing the network in the weights, hence removing unnecessary nonlinear effects of large changes in the weights. Apart from hypernetwork approaches, gradient-based methods can be used to optimize discrete hyperparameters also by adopting a continuous relaxation of the parameters. Such methods have been extensively used for the optimization of architecture hyperparameters in neural architecture search. === Evolutionary optimization === Evolutionary optimization is a methodology for the global optimization of noisy black-box functions. In hyperparameter optimization, evolutionary optimization uses evolutionary algorithms to search the space of hyperparameters for a given algorithm. Evolutionary hyperparameter optimization follows a process inspired by the biological concept of evolution: Create an initial population of random solutions (i.e., randomly generate tuples of hyperparameters, typically 100+) Evaluate the hyperparameter tuples and acquire their fitness function (e.g., 10-fold cross-validation accuracy of the machine learning algorithm with those hyperparameters) Rank the hyperparameter tuples by their relative fitness Replace the worst-performing hyperparameter tuples with new ones generated via crossover and mutation Repeat steps 2-4 until satisfactory algorithm performance is reached or is no longer improving. Evolutionary optimization has been used in hyperparameter optimization for statistical machine learning algorithms, automated machine learning, typical neural network and deep neural network architecture search, as well as training of the weights in deep neural networks. === Population-based === Population Based Training (PBT) learns both hyperparameter values and network weights. Multiple learning processes operate independently, using different hyperparameters. As with evolutionary methods, poorly performing models are iteratively replaced with models that adopt modified hyperparameter values and weights based on the better performers. This replacement model warm starting is the primary differentiator between PBT and other evolutionary methods. PBT thus allows the hyperparameters to evolve and eliminates the need for manual hypertuning. The process makes no assumptions regarding model architecture, loss functions or training procedures. PBT and its variants are adaptive methods: they update hyperparameters during the training of the models. On the contrary, non-adaptive methods have the sub-optimal strategy to assign a constant set of hyperparameters for the whole training. === Early stopping-based === A class of early stopping-based hyperparameter optimization algorithms is purpose-built for large search spaces of continuous and discrete hyperparameters, particularly when the computational cost to evaluate the performance of a set of hyperparameters is high. Irace implements the iterated racing algorithm, that focuses the search around the most promising configurations, using statistical tests to discard the ones that perform poorly. Another early stopping hyperparameter optimization algorithm is successive halving (SHA), which begins as a random search but periodically prunes low-performing models, thereby focusing computational resources on more promising models. Asynchronous successive halving (ASHA) further improves upon SHA's resource utilization profile by removing the need to synchronously evaluate a

Real-Time UML

Real-Time UML (RTUML) refers to the application of the Unified Modelling Language (UML) for the analysis, design, and implementation of real-time and embedded systems, where timing constraints, concurrency, and resource management are critical. It extends standard UML with profiles, notations, and semantics to handle hard and soft real-time requirements, such as modelling predictable response times and fault tolerance. RTUML is not a separate language but a methodology leveraging UML diagrams (e.g., statecharts, sequence diagrams) for time-sensitive applications like automotive controls, avionics, and medical devices. The term is closely associated with Bruce Powel Douglass, who popularised it through his books and the Harmony process for embedded software development. As of 2025, RTUML remains relevant in industries requiring certified systems, though its adoption varies with agile methodologies and model-driven engineering tools. == Background == Real-Time UML emerged in the late 1990s as UML was standardized by the Object Management Group (OMG) in 1997, addressing the need for object-oriented modeling in real-time systems previously dominated by procedural languages like C. Traditional real-time development relied on "bare metal" programming or theoretical models, but RTUML introduced visual notations for object structure, behaviour, and timing. Bruce Powel Douglass’s 1999 book, Real-Time UML: Developing Efficient Objects for Embedded Systems, formalised the approach, emphasising statecharts for concurrency and timing constraints. Later editions (2004, 2006) incorporated UML 2.0 features like activity and timing diagrams, aligning with OMG’s Real-Time Profile (now part of MARTE—Modelling and Analysis of Real-Time and Embedded Systems). The Harmony process integrates RTUML with executable models for simulation and code generation. RTUML addresses hard real-time systems (e.g., strict deadlines in avionics) versus soft real-time (e.g., media streaming), using UML extensions for schedulability analysis. == Key concepts == RTUML adapts UML diagrams and techniques for real-time needs: Statecharts and Behaviour Modelling: Extended state machines model reactive behaviour, using and-states for concurrency, pseudostates for transitions, and timing constraints (e.g., {duration < 10ms}). Examples include cardiac pacemaker models. Sequence and Interaction Diagrams: Capture message timing, priorities, and resource allocation in multi-threaded systems. Architectural Patterns: Define logical and physical architectures with active objects for concurrency and patterns like observer or publisher-subscriber. Timing and Constraints: Use Object Constraint Language (OCL) for specifying deadlines and priorities. Profiles and Extensions: OMG’s UML Profile for Schedulability, Performance, and Time (SPT) and MARTE add stereotypes like RT::ActiveObject. These support iterative development, from requirements to deployment, often with tools like IBM Rhapsody or Enterprise Architect. == Applications == RTUML is used in: Embedded Systems: Modelling automotive ECUs or UAV controls. Avionics and Defence: DO-178C-compliant designs for fault tolerance. Medical Devices: Pacemakers or ventilators with precise timing. Industrial Automation: RTOS task visualisation via sequence diagrams. Tools like IBM Rhapsody support RTUML for model-based development and code generation in C/C++. == Criticism and adoption == RTUML’s complexity can overwhelm simple systems, and its use in agile environments is limited, where lightweight diagrams are preferred. Surveys indicate UML (including RTUML) is used in 30–50% of embedded projects, often for documentation rather than full model-driven engineering. It remains standard in academia and certified industries like aerospace.

Software design

Software design is the process of conceptualizing how a software system will work before it is implemented or modified. Software design also refers to the direct result of the design process – the concepts of how the software will work which may be formally documented or may be maintained less formally, including via oral tradition. The design process enables a designer to model aspects of a software system before it exists with the intent of making the effort of writing the code more efficiently. Creativity, past experience, a sense of what makes "good" software, and a commitment to quality are success factors for a competent design. A software design can be compared to an architected plan for a house. High-level plans represent the totality of the house (e.g., a three-dimensional rendering of the house). Lower-level plans provide guidance for constructing each detail (e.g., the plumbing lay). Similarly, the software design model provides a variety of views of the proposed software solution. == Part of the overall process == In terms of the waterfall development process, software design is the activity that occurs after requirements analysis and before coding. Requirements analysis determines what the system needs to do without determining how it will do it, and thus, multiple designs can be imagined that satisfy the requirements. The design can be created while coding, without a plan or requirements analysis, but for more complex projects this is less feasible. Completing a design prior to coding allows for multidisciplinary designers and subject-matter experts to collaborate with programmers to produce software that is useful and technically sound. Sometimes, a simulation or prototype is created to model the system in an effort to determine a valid and good design. == Code as design == A common point of confusion with the term design in software is that the process applies at multiple levels of abstraction such as a high-level software architecture and lower-level components, functions and algorithms. A relatively formal process may occur at high levels of abstraction but at lower levels, the design process is almost always less formal where the only artifact of design may be the code itself. To the extent that this is true, software design refers to the design of the design. Edsger W. Dijkstra referred to this layering of semantic levels as the "radical novelty" of computer programming, and Donald Knuth used his experience writing TeX to describe the futility of attempting to design a program prior to implementing it: TEX would have been a complete failure if I had merely specified it and not participated fully in its initial implementation. The process of implementation constantly led me to unanticipated questions and to new insights about how the original specifications could be improved. == Artifacts == A design process may include the production of art Software design documentation such as flow chart, use case, Pseudocode, Unified Modeling Language model and other Fundamental modeling concepts. For user centered software, design may involve user experience design yielding a storyboard to help determine those specifications. Documentation may be reviewed to allow constraints, specifications and even requirements to be adjusted prior to coding. == Iterative design == Software systems inherently deal with uncertainties, and the size of software components can significantly influence a system's outcomes, both positively and negatively. Neal Ford and Mark Richards propose an iterative approach to address the challenge of identifying and right-sizing components. This method emphasizes continuous refinement as teams develop a more nuanced understanding of system behavior and requirements. The approach typically involves a cycle with several stages: A high-level partitioning strategy is established, often categorized as technical or domain-based. Guidelines for the smallest meaningful deployable unit, referred to as "quanta," are defined. While these foundational decisions are made early, they may be revisited later in the cycle if necessary. Initial components are identified based on the established strategy. Requirements are assigned to the identified components. The roles and responsibilities of each component are analyzed to ensure clarity and minimize overlap. Architectural characteristics, such as scalability, fault tolerance, and maintainability, are evaluated. Components may be restructured based on feedback from development teams. This cycle serves as a general framework and can be adapted to different domains. == Design principles == Design principles enable a software engineer to navigate the design process. Davis suggested principles which have been refined over time as: The design process should not suffer from "tunnel vision" A good designer should consider alternative approaches, judging each based on the requirements of the problem, the resources available to do the job. The design should be traceable to the analysis model Because a single element of the design model can often be traced back to multiple requirements, it is necessary to have a means for tracking how requirements have been satisfied by the design model. The design should not reinvent the wheel Systems are constructed using a set of design patterns, many of which have likely been encountered before. These patterns should always be chosen as an alternative to reinvention. Time is short and resources are limited; design time should be invested in representing (truly new) ideas by integrating patterns that already exist (when applicable). The design should "minimize the intellectual distance" between the software and the problem as it exists in the real world That is, the structure of the software design should, whenever possible, mimic the structure of the problem domain. The design should exhibit uniformity and integration A design is uniform if it appears fully coherent. In order to achieve this outcome, rules of style and format should be defined for a design team before design work begins. A design is integrated if care is taken in defining interfaces between design components. The design should be structured to accommodate change The design concepts discussed in the next section enable a design to achieve this principle. The design should be structured to degrade gently, even when aberrant data, events, or operating conditions are encountered Well-designed software should never "bomb"; it should be designed to accommodate unusual circumstances, and if it must terminate processing, it should do so in a graceful manner. Design is not coding, coding is not design Even when detailed procedural designs are created for program components, the level of abstraction of the design model is higher than the source code. The only design decisions made at the coding level should address the small implementation details that enable the procedural design to be coded. The design should be assessed for quality as it is being created, not after the fact A variety of design concepts and design measures are available to assist the designer in assessing quality throughout the development process. The design should be reviewed to minimize conceptual (semantic) errors There is sometimes a tendency to focus on minutiae when the design is reviewed, missing the forest for the trees. A design team should ensure that major conceptual elements of the design (omissions, ambiguity, inconsistency) have been addressed before worrying about the syntax of the design model. == Design concepts == Design concepts provide a designer with a foundation from which more sophisticated methods can be applied. Design concepts include: Abstraction Reducing the information content of a concept or an observable phenomenon, typically to retain only information that is relevant for a particular purpose. It is an act of Representing essential features without including the background details or explanations. Architecture The overall structure of the software and the ways in which that structure provides conceptual integrity for a system. Good software architecture will yield a good return on investment with respect to the desired outcome of the project, e.g. in terms of performance, quality, schedule and cost. Control hierarchy A program structure that represents the organization of a program component and implies a hierarchy of control. Data structure Representing the logical relationship between elements of data. Design pattern A designer may identify a design aspect of the system that has solved in the past. The reuse of such patterns can increase software development velocity. Information hiding Modules should be specified and designed so that information contained within a module is inaccessible to other modules that have no need for such information. Modularity Dividing the solution into parts (modules). Refinement The process of elaboration. A hierarchy is developed by decomposing a macrosco

OpenFog Consortium

The OpenFog Consortium (sometimes stylized as Open Fog Consortium) was a consortium of high tech industry companies and academic institutions across the world aimed at the standardization and promotion of fog computing in various capacities and fields. The consortium was founded by Cisco Systems, Intel, Microsoft, Princeton University, Dell, and ARM Holdings in 2015 and now has 57 members across the North America, Asia, and Europe, including Forbes 500 companies and noteworthy academic institutions. The OpenFog consortium merged with the Industrial Internet Consortium, now the Industry IoT Consortium, on January 31, 2019. == History == OpenFog was created on November 19, 2015, by ARM Holdings, Cisco Systems, Dell, Intel, Microsoft, and Princeton University. The idea for a consortium centered on the advancement and dissemination of fog computing was thought up by Helder Antunes, a Cisco executive with a history in IoT, Mung Chiang, then a Princeton University professor and now President of Purdue University, and Dr. Tao Zhang, a Cisco Distinguished Engineer and CIO for the IEEE Communications Society then and now a manager at the National Institute of Standards and Technologies (NIST). The project was executed from concept to launch by Armando Pereira at PVentures Consulting, a Silicon Valley–based high-tech consulting firm. OpenFog released its reference architecture for fog computing on February 13, 2017. The Fog World Congress 2017, with Dr. Tao Zhang as its General Chair, was hosted in October 2017 by OpenFog, in conjunction with the IEEE Communications Society, as the first congress devoted to fog computing. == Administration == The OpenFog Consortium was governed by its board of directors, which is chaired by Cisco Senior Director Helder Antunes. The board of directors is made up of 11 seats, each representing one of the following companies and institutions: ARM, AT&T, Cisco, Dell, Intel, Microsoft, Princeton University, IEEE, GE, ZTE and Shanghai Tech University. The consortium's general membership comprised 13 academic members: Aalto University, Arizona State University, California Institute of Technology, Georgia State University, National Chiao Tung University, National Taiwan University, Shanghai Research Centre for Wireless Communication, Chinese University of Hong Kong, University of Colorado Boulder, University of Southern California, University of Pisa, Vanderbilt University, Wayne State University, and 20 additional members: Hitachi, Internet Initiative Japan, Itochu, Kii, Nebbiolo, PrismTech, NEC, NGD Systems, NTT Communications, OSIsoft, Real-time Innovations, relayr, Sakura Internet, Stichting imec Nederland, Toshiba, TTT Tech, Fujitsu, FogHorn Systems, TTTech and MARSEC. == Published work == The OpenFog Consortium published the white paper, "OpenFog Reference Architecture". This document outlines the eight pillars of an OpenFog architecture:Security; Scalability; Open; Autonomy; Programmability; RAS (reliability, availability and serviceability); Agility; and Hierarchy. It also incorporates a glossary for fog computing terms. In July 2018, the IEEE Standards Association announced it had adopted the OpenFog Reference Architecture as the first standard for fog computing.

Hybrid intelligent system

Hybrid intelligent system denotes a software system which employs, in parallel, a combination of methods and techniques from artificial intelligence subfields, such as: Neuro-symbolic systems Neuro-fuzzy systems Hybrid connectionist-symbolic models Fuzzy expert systems Connectionist expert systems Evolutionary neural networks Genetic fuzzy systems Rough fuzzy hybridization Reinforcement learning with fuzzy, neural, or evolutionary methods as well as symbolic reasoning methods. From the cognitive science perspective, every natural intelligent system is hybrid because it performs mental operations on both the symbolic and subsymbolic levels. For the past few years, there has been an increasing discussion of the importance of A.I. Systems Integration. Based on notions that there have already been created simple and specific AI systems (such as systems for computer vision, speech synthesis, etc., or software that employs some of the models mentioned above) and now is the time for integration to create broad AI systems. Proponents of this approach are researchers such as Marvin Minsky, Ron Sun, Aaron Sloman, Angelo Dalli and Michael A. Arbib. An example hybrid is a hierarchical control system in which the lowest, reactive layers are sub-symbolic. The higher layers, having relaxed time constraints, are capable of reasoning from an abstract world model and performing planning (even by hybrid wisdom). Intelligent systems usually rely on hybrid reasoning processes, which include induction, deduction, abduction and reasoning by analogy.

Client-side persistent data

Client-side persistent data or CSPD is a term used in computing for storing data required by web applications to complete internet tasks on the client-side as needed rather than exclusively on the server. As a framework it is one solution to the needs of Occasionally connected computing or OCC. A major challenge for HTTP as a stateless protocol has been asynchronous tasks. The AJAX pattern using XMLHttpRequest was first introduced by Microsoft in the context of the Outlook e-mail product. The first CSPD were the 'cookies' introduced by the Netscape Navigator. ActiveX components which have entries in the Windows registry can also be viewed as a form of client-side persistence.