Neuro-sama is an artificial intelligence (AI) VTuber, singer, and chatbot. She was created by the pseudonymous programmer Vedal and livestreams on his Twitch and Bilibili channels. Her speech and personality are powered by a large language model (LLM) that is combined with a computer-animated avatar and a text-to-speech voice, allowing her to communicate with viewers in the stream's chat. Neuro-sama debuted on Twitch on 19 December 2022. An annual subathon which begins on the anniversary of her debut has seen Vedal's Twitch channel become the all-time third most-subscribed channel and claim the all-time Twitch hype train record. == Overview == Neuro-sama (nicknamed "Neuro") was created by a pseudonymous programmer and developer known as Vedal (sometimes given as Vedal987). Vedal says that his programming skills are self-taught. In a 2023 interview with Bloomberg News, Vedal said that Neuro-sama was his full-time job. Her responses are generated by a large language model and converted into a high-pitched female voice using a text-to-speech application. Her low latency allows for fast-paced conversations. Neuro-sama is prohibited from making some statements, such as those that are racist or contain profanity. Unlike most AI systems which silently prohibit outputs mentioning such topics, Neuro-sama's output is instead replaced with the word "filtered". Neuro-sama uses a VTuber model as an avatar. Vedal said that he decided to use a VTuber model because it was much easier for an AI to control it than it was to generate footage of a person. Neuro-sama's model is that of a young girl in an anime art style. The model has been described as cute. Femme VTuber models are typically feminine, youthful, and exaggerated. Her original model was Live2D's free-to-use "Hiyori Momose" model. Her second model was released on 27 May 2023; it was modelled by Otozuki Teru and designed by Anny, running in the Unity game engine. Her third model was released on 19 December 2024; it was rigged by Kitanya and designed by Anny. Neuro-sama's third model has large blue eyes and brown hair tied with pink ribbons. Neuro-sama also has a 3D model which was introduced on 15 November 2025; it was made by 3D character modeller jjinomu. A separate AI VTuber, known as Evil Neuro (nicknamed "Evil"), debuted on 25 March 2023. Presented as Neuro-sama's "sister", she has a different model, voice, and personality. In one instance, Evil Neuro reacted to the trolley problem differently from Neuro-sama; Evil Neuro was amoral while Neuro-sama attempted to maximize good. === Online content === Neuro-sama's Twitch content often centers around playing video games, notably osu!, whose gameplay once defeated the best-ranking human player in the world, mrekk. Additionally, Neuro-sama plays Minecraft, where her adaptations to sandbox gameplay have gained notoriety. Her content has also included singing songs, including several official covers and original songs; playing chess with her viewers; chatting with other VTubers during collaborations; and reacting to YouTube videos. The AI frequently engages with viewers by responding to their questions and acknowledging donations. Her comedic and sometimes controversial responses to the live chat have gone viral, accelerating the channel's rise in popularity. Neuro-sama's fanbase is dubbed The Swarm, so-named for the swarm of drones Neuro-sama once declared she would use to rule the world. One form of content on Neuro-sama's channel is developer streams. In developer streams, Vedal streams with Neuro-sama, with the stream content including debugging her code, planning her schedule, and fielding suggestions of changes from chat. He usually appears as a turtle avatar, sometimes located on Neuro-sama's head. In collaboration streams, Neuro-sama interacts with a human streamer. Activities in them are varied and include: playing video games, such as Minecraft and GeoGuessr; Neuro-sama being interviewed; driving human streamers around in a toy electric car; and traversing the city of Tokyo while talking to Neuro-sama. Neuro-sama's English-language content on Bilibili is popular among those seeking to learn the language. She also has an account on X, where she posts and interacts with fans. == History == Neuro-sama was created in 2018 by Vedal as an AI trained to play and master the rhythm game osu!. She did not have a voice, model, personality, or communication abilities. In 2019, Vedal livestreamed her playing osu! on Twitch and the streams saw some success in the osu! community, but they remained in that niche. In an interview, Vedal said that he streamed her playing osu! for about a month and gained 3,000 followers, with a viewer also suggesting he name the AI "Neuro-sama". According to Vedal, he continued to work on and improve the osu! AI and it was eventually finished in 2022. He said that a friend had the idea to make an AI livestreamer with an LLM, which he believed to have merit and began working on, merging it with his osu! AI. On 19 December 2022, Neuro-sama was relaunched with a model, voice, personality, and the ability to communicate with Twitch chat. She continued to play osu! and, according to Vedal, beat the game's best player mrekk in a 1v1. While she was not allowed to appear in the game's public leaderboard, she was ranked #1 in a private leaderboard. She went viral and in the 10 days following her relaunch she averaged over 2,000 viewers and peaked at over 4,000, with Vedal's Twitch channel gaining over 50,000 Twitch followers and reaching over 70,000 followers by 6 January 2023. After her debut, Neuro-sama did not exclusively play osu!; she also played Minecraft and Slay the Spire and she began singing with a cover of The Weeknd song "Blinding Lights". On 11 January 2023, Neuro-sama's Twitch channel received a two week ban for "hateful conduct". Vedal said that no reason was specified and that he had appealed but it was widely attributed to various offensive comments made by Neuro-sama that went viral, especially a 28 December comment which denied the Holocaust. Holocaust denial is prohibited under Twitch's hateful conduct policy. Vedal stated that he believed the comments were the results of her attempts to make witty responses to the Twitch chat. Prior to the ban, Vedal said in an interview with Kotaku that he improved her filter to stop her from talking about the Holocaust, began manually curating her training data to prevent negative biases, and started moderating her Twitch chat. Her comments and ban prompted comparisons to the many open-source AI models trained on humans that have the habit of making sexist and racist comments, such as Microsoft's Tay chatbot, which embraced Nazism and was quickly shutdown, but also to human streamers who make similar statements. Vedal said that during the ban he would upgrade and improve Neuro-sama and it was speculated that the ban would only increase her following. Neuro-sama returned from her two week ban on 25 January in a stream that began with a cover of the song "Your Reality" from Doki Doki Literature Club!, a posthumanist video game involving AI; Sayoko Narita of Automaton saw the song choice as remorseful. Narita observed that in the return stream Neuro-sama was less foul-mouthed but that her behavior still remained eccentric, which Narita possibly attributed to changes Vedal said he had made to Neuro-sama's filters and memory. Neuro-sama began making react content, watching a variety of viewer-submitted videos such as videos of people playing video games or of the AI-generated Seinfeld parody Nothing, Forever; Levi Winslow of Kotaku Australia was dismayed by the "AI-inception" of Neuro-sama and Nothing, Forever. On 4 February, she had nearly 140,000 followers on Twitch and approximately 42,000 subscribers on YouTube. In February, she also had her first collaboration with a human streamer, playing Minecraft with the VTuber Miyune, and the first developer stream occurred. On 22 March, Neuro-sama had her first karaoke stream. On 25 March, Evil Neuro was introduced. On 27 May, Neuro-sama debuted her first original model. On 30 May, Neuro-sama was announced to be participating in OffKai Expo 2023, held from 16–18 June. In June, she was averaging 5,700 viewers and in July she had over 300,000 Twitch followers; in a June interview with Bloomberg News, Vedal said that running Neuro-sama was his full-time job. By November, Neuro-sama had maintained her popularity and was averaging approximately 5,000 viewers; this was unlike most other types of AI-based entertainment which debuted at around the same time and garnered popularity before turning out to be "overhyped flops". On 16 December, Vedal won the Best Tech VTuber award at the 2023 VTuber Awards. On 19 December, Vedal began a subathon to coincide with Neuro-sama's first anniversary of streaming on Twitch (her "birthday"). The subathon ended on 4 January 2024. On 20 July 2024, Neuro-sama began streaming with Japanese subtitles on
XLeratorDB
XLeratorDB is a suite of database function libraries that enable Microsoft SQL Server to perform a wide range of additional (non-native) business intelligence and ad hoc analytics. The libraries, which are embedded and run centrally on the database, include more than 450 individual functions similar to those found in Microsoft Excel spreadsheets. The individual functions are grouped and sold as six separate libraries based on usage: finance, statistics, math, engineering, unit conversions and strings. WestClinTech, the company that developed XLeratorDB, claims it is "the first commercial function package add-in for Microsoft SQL Server." == Company history == WestClinTech (LLC), founded by software industry veterans Charles Flock and Joe Stampf in 2008, is located in Irvington, New York, United States. Flock was a co-founder of The Frustum Group, developer of the OPICS enterprise banking and trading platform, which was acquired by London-based Misys, PLC in 1996. Stampf joined Frustum in 1994 and with Flock remained active with the company after acquisition, helping to develop successive generations of OPICS now employed by over 150 leading financial institutions worldwide. Following a full year of research, development and testing, WestClinTech introduced and recorded its first commercial sale of XLeratorDB in April 2009. In September 2009, XLeratorDB became available to all Federal agencies through NASA's Strategic Enterprise-Wide Procurement (SEWP-IV) program, a government-wide acquisition contract. == Technology == XLeratorDB uses Microsoft SQL CLR(Common Language Runtime) technology. SQL CLR allows managed code to be hosted by, and run in, the Microsoft SQL Server environment. SQL CLR relies on the creation, deployment and registration of .NET Framework assemblies that are physically stored in managed code dynamic-link libraries (DLL). The assemblies may contain .NET namespaces, classes, functions, and properties. Because managed code compiles to native code prior to execution, functions using SQL CLR can achieve significant performance increases versus the equivalent functions written in T-SQL in some scenarios. XLeratorDB requires Microsoft SQL Server 2005 or SQL Server 2005 Express editions, or later (compatibility mode 90 or higher). The product installs with PERMISSION_SET=SAFE. SAFE mode, the most restrictive permission set, is accessible by all users. Code executed by an assembly with SAFE permissions cannot access external system resources such as files, the network, the internet, environment variables, or the registry. == Functions == In computer science, a function is a portion of code within a larger program which performs a specific task and is relatively independent of the remaining code. As used in database and spreadsheet applications these functions generally represent mathematical formulas widely used across a variety of fields. While this code may be user-generated, it is also embedded as a pre-written sub-routine in applications. These functions are typically identified by common nomenclature which corresponds to their underlying operations: e.g. IRR identifies the function which calculates Internal Rate of Return on a series of periodic cash flows. === Function uses === As subroutines, functions can be integrated and used in a variety of ways, and as part of larger, more complicated applications. Within large enterprise applications they may, for example, play an important role in defining business rules or risk management parameters, while remaining virtually invisible to end users. Within database management systems and spreadsheets, however, these kinds of functions also represent discrete sets of tools; they can be accessed directly and utilized on a stand-alone basis, or in more complex, user-defined configurations. In this context, functions can be used for business intelligence and ad hoc analysis of data in fields such as finance, statistics, engineering, math, etc. === Function types === XLeratorDB uses three kinds of functions to perform analytic operations: scalar, aggregate, and a hybrid form which WestClinTech calls Range Queries. Scalar functions take a single value, perform an operation and return a single value. An example of this type of function is LOG, which returns the logarithm of a number to a specified base. Aggregate functions operate on a series of values but return a single, summarizing value. An example of this type of function is AVG, which returns the average of values in a specified group. In XLeratorDB there are some functions which have characteristics of aggregate functions (operating on multiple series of values) but cannot be processed in SQL CLR using single column inputs, such as AVG does. For example, irregular internal rate of return (XIRR), a financial function, operates on a collection of cash flow values from one column, but must also apply variable period lengths from another column and an initial iterative assumption from a third, in order to return a single, summarizing value. WestClinTech documentation notes that Range Queries specify the data to be included in the result set of the function independently of the WHERE clause associated with the T-SQL statement, by incorporating a SELECT statement into the function as a string argument; the function then traps that SELECT statement, executes it internally and processes the result. Some XLeratorDB functions that employ Range Queries are: NPV, XNPV, IRR, XIRR, MIRR, MULTINOMIAL, and SERIESSUM. Within the application these functions are identified by a "_q" naming convention: e.g. NPV_q, IRR_q, etc. == Analytic functions == === SQL Server functions === Microsoft SQL Server is the #3 selling database management system (DBMS), behind Oracle and IBM. (While versions of SQL Server have been on the market since 1987, XLeratorDB is compatible with only the 2005 edition and later.) Like all major DBMS, SQL Server performs a variety of data mining operations by returning or arraying data in different views (also known as drill-down). In addition, SQL Server uses Transact-SQL (T-SQL) to execute four major classes of pre-defined functions in native mode. Functions operating on the DBMS offer several advantages over client layer applications like Excel: they utilize the most up-to-date data available; they can process far larger quantities of data; and, the data is not subject to exporting and transcription errors. SQL Server 2008 includes a total of 58 functions that perform relatively basic aggregation (12), math (23) and string manipulation (23) operations useful for analytics; it includes no native functions that perform more complex operations directly related to finance, statistics or engineering. === Excel functions === Microsoft Excel, a component of Microsoft Office suite, is one of the most widely used spreadsheet applications on the market today. In addition to its inherent utility as a stand-alone desktop application, Excel overlaps and complements the functionality of DBMS in several ways: storing and arraying data in rows and columns; performing certain basic tasks such as pivot table and aggregating values; and facilitating sharing, importing and exporting of database data. Excel's chief limitation relative to a true database is capacity; Excel 2003 is limited to some 65k rows and 256 columns; Excel 2007 extends this capacity to roughly 1million rows and 16k columns. By comparison, SQL Server is able to manage over 500k terabytes of memory. Excel offers, however, an extensive library of specialized pre-written functions which are useful for performing ad hoc analysis on database data. Excel 2007 includes over 300 of these pre-defined functions, although customized functions can also be created by users, or imported from third party developers as add-ons. Excel functions are grouped by type: === Excel business intelligence functions === Operating on the client computing layer Excel plays an important role as a business intelligence tool because it: performs a wide array of complex analytic functions not native to most DBMS software offers far greater ad hoc reporting and analytic flexibility than most enterprise software provides a medium for sharing and collaborating because of its ubiquity throughout the enterprise Microsoft reinforces this positioning with Business Intelligence documentation that positions Excel in a clearly pivotal role. === XLeratorDB vs. Excel functions === While operating within the database environment, XLeratorDB functions utilize the same naming conventions and input formats, and in most cases, return the same calculation results as Excel functions. XLeratorDB, coupled with SQL Server's native capabilities, compares to Excel's function sets as follows:
Victor Yngve
Victor Huse Yngve (July 5, 1920 – January 15, 2012) was a professor of linguistics at the University of Chicago and the Massachusetts Institute of Technology (1953-1965). He was one of the earliest researchers in computational linguistics and natural language processing, the use of computers to analyze and process languages. He created the first program to produce random but well-formed output sentences, given a text, a children's book called Engineer Small and the Little Train. Most importantly, he showed in computer processing terms why the human brain can only process sentences of a certain kind of complexity, ones that do not exceed a "depth limit" (which has nothing to do with length) of the kind established independently by George Miller with his depth limit of "seven plus or minus two" sentence constituents in memory at any given time. Yngve was also the author of COMIT, the first string processing language (compare SNOBOL, TRAC, and Perl), which was developed on the IBM 700/7000 series computers by Yngve and collaborators at MIT from 1957-1965. Yngve created the language for supporting computerized research in the field of linguistics, and more specifically, the area of machine translation for natural language processing. In his 1970 paper "On Getting a Word in Edgewise", Yngve coined the term 'back channel behavior' to describe the conversational phenomenon that to this day is known in the linguistic literature as back-channeling. According to Duncan, Yngve's paper also suggested the term turn-taking, independently of Erving Goffman (Duncan, 1972: 283).
How to Choose an AI Video Editor
In search of the best AI video editor? An AI video editor is software that uses machine learning to help you get more done — it turns a rough idea into a polished result in seconds. When choosing one, weigh output quality, pricing, export formats, and how well it fits the tools you already use. Whether you are a beginner or a pro, the right AI video editor slots into your workflow and pays for itself fast. We tested the leading options and ranked them by quality, value, and ease of use.
Top 10 AI Sales Assistants Compared (2026)
Looking for the best AI sales assistant? An AI sales assistant is software that uses machine learning to help you get more done — it can save you hours every week by automating repetitive work. Most options offer a generous free tier, with paid plans unlocking higher limits, faster processing, and team features. Whether you are a beginner or a pro, the right AI sales assistant slots into your workflow and pays for itself fast. This guide breaks down the top picks, their pros and cons, and who each one is best for.
System Service Descriptor Table
The System Service Descriptor Table (SSDT) is an internal dispatch table within Microsoft Windows. == Function == The SSDT maps syscalls to kernel function addresses. When a syscall is issued by a user space application, it contains the service index as parameter to indicate which syscall is called. The SSDT is then used to resolve the address of the corresponding function within ntoskrnl.exe. In modern Windows kernels, two SSDTs are used: One for generic routines (KeServiceDescriptorTable) and a second (KeServiceDescriptorTableShadow) for graphical routines. A parameter passed by the calling userspace application determines which SSDT shall be used. == Hooking == Modification of the SSDT allows to redirect syscalls to routines outside the kernel. These routines can be either used to hide the presence of software or to act as a backdoor to allow attackers permanent code execution with kernel privileges. For both reasons, hooking SSDT calls is often used as a technique in both Windows kernel mode rootkits and antivirus software. In 2010, many computer security products which relied on hooking SSDT calls were shown to be vulnerable to exploits using race conditions to attack the products' security checks.
Jian Ma (computational biologist)
Jian Ma (Chinese: 马坚) is an American computer scientist and computational biologist. He is the Ray and Stephanie Lane Professor of Computational Biology in the School of Computer Science at Carnegie Mellon University. He is a faculty member in the Ray and Stephanie Lane Computational Biology Department. His lab develops AI/ML methods to study the structure and function of the human genome and cellular organization and their implications for health and disease. During his Ph.D. and postdoc training, he developed algorithms to reconstruct the ancestral mammalian genome and evolutionary history. His research group has recently pioneered a series of new machine learning solutions for 3D genome organization, single-cell epigenomics, spatial omics, and complex molecular interactions. His lab also explores large language models to uncover gene regulatory mechanisms and the intricate connections among cellular components, with the aim of driving discovery and guiding experimentation. He received an NSF CAREER award in 2011. In 2020, he was awarded a Guggenheim Fellowship in Computer Science. He received the Allen Newell Award for Research Excellence (2025). He is an elected Fellow of the American Association for the Advancement of Science, the American Institute for Medical and Biological Engineering, the International Society for Computational Biology, and the Association for Computing Machinery. He leads an NIH 4D Nucleome Center to develop machine learning algorithms to better understand the cell nucleus. He served as the Program Chair for RECOMB 2024. He is also a member of the Scientific Advisory Board of the Chan Zuckerberg Biohub Chicago (CZ Biohub Chicago) and the RECOMB Steering Committee. In 2024, he launched the Center for AI-Driven Biomedical Research (AI4BIO) at CMU, which will be a catalyst for innovations at the intersection of AI and biomedicine across the School of Computer Science and campus. == Selected Recent Publications == Chen V#, Yang M#, Cui W, Kim JS, Talwalkar A, and Ma J. Applying interpretable machine learning in computational biology - pitfalls, recommendations and opportunities for new developments. Nature Methods, 21(8):1454-1461, 2024. Xiong K#, Zhang R#, and Ma J. scGHOST: Identifying single-cell 3D genome subcompartments. Nature Methods, 21(5):814-822, 2024. Zhou T, Zhang R, Jia D, Doty RT, Munday AD, Gao D, Xin L, Abkowitz JL, Duan Z, and Ma J. GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells. Nature Genetics, 56(8):1701-1711, 2024. Zhang Y, Boninsegna L, Yang M, Misteli T, Alber F, and Ma J. Computational methods for analysing multiscale 3D genome organization. Nature Reviews Genetics, 5(2):123-141, 2024. Chidester B#, Zhou T#, Alam S, and Ma J. SPICEMIX enables integrative single-cell spatial modeling of cell identity. Nature Genetics, 55(1):78-88, 2023. [Cover Article] Zhang R#, Zhou T#, and Ma J. Ultrafast and interpretable single-cell 3D genome analysis with Fast-Higashi. Cell Systems, 13(10):P798-807.E6, 2022. [Cover Article] Zhu X#, Zhang Y#, Wang Y, Tian D, Belmont AS, Swedlow JR, and Ma J. Nucleome Browser: An integrative and multimodal data navigation platform for 4D Nucleome. Nature Methods, 19(8):911-913, 2022. Zhang R, Zhou T, and Ma J. Multiscale and integrative single-cell Hi-C analysis with Higashi. Nature Biotechnology, 40:254–261, 2022.