Cyborg

Cyborg

A cyborg () is a being with both organic and biomechatronic body parts. It is a portmanteau of cybernetic and organism. The term was coined in 1960 by Manfred Clynes and Nathan S. Kline. In contrast to biorobots and androids, the term cyborg applies to a living organism that has undergone restoration of function or enhancements of abilities due to the integration of some artificial component or technology that relies on feedback. == Description and definition == Alternative names for a cyborg include cybernetic organism, cyber-organism, cyber-organic being, cybernetically enhanced organism, cybernetically augmented organism, technorganic being, techno-organic being, and techno-organism. Unlike bionics, biorobotics, or androids, a cyborg is an organism that has restored function or, especially, enhanced abilities due to the integration of some artificial component or technology that relies on some sort of feedback, for example: prostheses, artificial organs, implants or, in some cases, wearable technology. Cyborg technologies may enable or support collective intelligence. A related idea is the "augmented human". While cyborgs are commonly thought of as mammals, including humans, the term can apply to any organism. === Placement and distinctions === D. S. Halacy's Cyborg: Evolution of the Superman (1965) featured an introduction which spoke of a "new frontier" that was "not merely space, but more profoundly the relationship between 'inner space' to 'outer space' – a bridge...between mind and matter." In "A Cyborg Manifesto", Donna Haraway rejects the notion of rigid boundaries between humanity and technology, arguing that, as humans depend on more technology over time, humanity and technology have become too interwoven to draw lines between them. She believes that since we have allowed and created machines and technology to be so advanced, there should be no reason to fear what we have created, and cyborgs should be embraced because they are part of human identities. However, Haraway has also expressed concern over the contradictions of scientific objectivity and the ethics of technological evolution, and has argued that "There are political consequences to scientific accounts of the world." === Biosocial definition === According to some definitions of the term, the physical attachments that humans have with even the most basic technologies have already made them cyborgs. In a typical example, a human with an artificial cardiac pacemaker or implantable cardioverter-defibrillator would be considered a cyborg, since these devices measure voltage potentials in the body, perform signal processing, and can deliver electrical stimuli, using a synthetic feedback mechanism to keep that person alive. Implants, especially cochlear implants, that combine mechanical modification with any kind of feedback response are also cybernetic enhancements. Some theorists cite such modifications as contact lenses, hearing aids, smartphones, or intraocular lenses as examples of fitting humans with technology to enhance their biological capabilities. The emerging trend of implanting microchips inside the body (mainly the hands), to make financial operations like a contactless payment, or basic tasks like opening a door, has been erroneously marketed as more recent examples of cybernetic enhancement. The latter has not yet seen significant traction outside niche areas in Scandinavia and in actual function is little more than a pre-programmed Radio-frequency identification (RFID) microchip encased in glass that does not interact with the human body (it is the same technology used in the microchips injected into animals for ease of identification), thus not fitting the definition of a cybernetic implant. As cyborgs currently are on the rise, some theorists argue there is a need to develop new definitions of aging. For instance, a bio-techno-social definition of aging has been suggested. The term is also used to address human-technology mixtures in the abstract. This includes not only commonly used pieces of technology such as phones, computers, the Internet, and so on, but also artifacts that are not usually considered technology; for example, pen and paper, and speech and language. When augmented with these technologies and connected in communication with people in other times and places, a person becomes capable of more than they were before. An example is a computer, which gains power by using Internet protocols to connect with other computers. Another example is a social-media bot—either a bot-assisted human or a human-assisted-bot—used to target social media with likes and shares. Cybernetic technologies thus include highways, pipes, electrical wiring, buildings, electrical plants, libraries, and other infrastructural constructs. Bruce Sterling, in his Shaper/Mechanist universe, suggested an idea of an alternative cyborg called 'Lobster', which is made not by using internal implants, but by using an external shell (e.g. a powered exoskeleton). The computer game Deus Ex: Invisible War prominently features cyborgs called Omar, Russian for 'lobster'. === Evolutionary perspective === In 1994, Hans Hass formulated a scientific view of the human-machine hybrids he called "hypercells". They can expand their biological cell body with artificial artifacts and thus expand their performance body. The theory of hypercells or Homo proteus, as Hass called the human-machine hybrid to distinguish Homo sapiens, extends Charles Darwin's theory of evolution and deals with the course of evolution beyond humans. In his 2019 book Novacene, James Lovelock used the term "cyborgs" to refer to the next generation of beings who will become the "understanders of the future" and "lead the cosmos to self-knowledge". While acknowledging the organic component in Clynes' and Kline's definition, he proposed that these cyborgs "will have designed and built themselves from the artificial intelligence systems we have already constructed", and used the term cyborg "to emphasize that the new intelligent beings will have arisen, like us, from Darwinian evolution." == Origins == The concept of a man-machine mixture was widespread in science fiction before World War II. As early as 1843, Edgar Allan Poe described a man with extensive prostheses in the short story "The Man That Was Used Up". In 1911, Jean de La Hire introduced the Nyctalope, a science fiction hero who was perhaps the first literary cyborg, in Le Mystère des XV (later translated as The Nyctalope on Mars). Nearly two decades later, Edmond Hamilton presented space explorers with a mixture of organic and machine parts in his 1928 novel The Comet Doom. He later featured the talking, living brain of an old scientist, Simon Wright, floating in a transparent case, and in all the adventures of his famous hero, Captain Future. In 1944, in the short story "No Woman Born", C. L. Moore wrote of Deirdre, a dancer, whose body was burned completely and whose brain was placed in a faceless but beautiful and supple mechanical body. In 1960, the term "cyborg" was coined by Manfred E. Clynes and Nathan S. Kline to refer to their conception of an enhanced human being who could survive in extraterrestrial environments: For the exogenously extended organizational complex functioning as an integrated homeostatic system unconsciously, we propose the term 'Cyborg'. Their concept was the outcome of thinking about the need for an intimate relationship between human and machine as the new frontier of space exploration was beginning to develop. A designer of physiological instrumentation and electronic data-processing systems, Clynes was the chief research scientist in the Dynamic Simulation Laboratory at Rockland State Hospital in New York. The term first appears in print 5 months earlier when The New York Times reported on the "Psychophysiological Aspects of Space Flight Symposium" where Clynes and Kline first presented their paper: A cyborg is essentially a man-machine system in which the control mechanisms of the human portion are modified externally by drugs or regulatory devices so that the being can live in an environment different from the normal one. Thereafter, Hamilton would first use the term "cyborg" explicitly in the 1962 short story, "After a Judgment Day", to describe the "mechanical analogs" called "Charlies," explaining that "[c]yborgs, they had been called from the first one in the 1960s...cybernetic organisms." The 1972 novel Cyborg by Martin Caidin introduced the character of bionic government agent Steve Austin, and was adapted into the popular television series The Six Million Dollar Man, which ran from 1973 to 1978. In 2001, a book titled Cyborg: Digital Destiny and Human Possibility in the Age of the Wearable computer was published by Doubleday. Some of the ideas in the book were incorporated into the documentary film Cyberman that same year. == Cyborg tissues in engineering == Cyborg tissues structured with carbon nanotubes and plan

LMArena

Arena (formerly LMArena and Chatbot Arena) is a public, web-based platform that evaluates large language models (LLMs). Users enter prompts for two anonymous models to respond to and vote on the model that gave the better response, after which the models' identities are revealed. Users can also choose models to test themselves via the "Direct" selection. Companies which have supplied the company with their large language models include OpenAI, Google DeepMind, and Anthropic. The website has been used for preview releases of upcoming models. Chinese company DeepSeek tested its prototype models in the Arena months before its R1 model gained attention in Western media. Other notable pre-release models include OpenAI's GPT-5 under the codename "summit" and Google DeepMind's Gemini 2.5 Flash Image (an image-generation and editing model) under the codename "Nano Banana". Research has identified specific limitations in Arena's methodology. == History == Chatbot Arena was released on April 24, 2023. In June 2024, Chatbot Arena added image support. In September 2024, Chatbot Arena moved to its own dedicated domain name, lmarena.ai (or LMArena). In April 2025, Meta released Llama 4. Llama 4 Maverick beat GPT-4o and Gemini 2.0 Flash on LMArena, but the version of Maverick on LMArena unfairly differed from the publicly available version. LMArena updated their policies in response. In April 2025, LMArena incorporated as an independent company. That May, LMArena raised $100 million in a seed funding round, valuing the company at $600 million. Participants in the seed funding round included Andreessen Horowitz, UC Investments, Lightspeed Venture Partners, Felicis Ventures, and Kleiner Perkins. On January 6, 2026, LMArena announced the closing of a $150 million Series A funding round, bringing the company’s post-money valuation to approximately $1.7 billion. The round was led by Felicis and UC Investments (University of California), with participation from Andreessen Horowitz, The House Fund, LDVP, Kleiner Perkins, Lightspeed Venture Partners, and Laude Ventures. In January 2026, LMArena added video support. On January 28, 2026, LMArena rebranded to "Arena".

Linear discriminant analysis

Linear discriminant analysis (LDA), normal discriminant analysis (NDA), canonical variates analysis (CVA), or discriminant function analysis is a generalization of Fisher's linear discriminant, a method used in statistics and other fields, to find a linear combination of features that characterizes or separates two or more classes of objects or events. The resulting combination may be used as a linear classifier, or, more commonly, for dimensionality reduction before later classification. LDA is closely related to analysis of variance (ANOVA) and regression analysis, which also attempt to express one dependent variable as a linear combination of other features or measurements. However, ANOVA uses categorical independent variables and a continuous dependent variable, whereas discriminant analysis has continuous independent variables and a categorical dependent variable (i.e. the class label). Logistic regression and probit regression are more similar to LDA than ANOVA is, as they also explain a categorical variable by the values of continuous independent variables. These other methods are preferable in applications where it is not reasonable to assume that the independent variables have a normal distribution, which is a fundamental assumption of the LDA method. LDA is also closely related to principal component analysis (PCA) and factor analysis in that they both look for linear combinations of variables which best explain the data. LDA explicitly attempts to model the difference between the classes of data. PCA, in contrast, does not take into account any difference in class, and factor analysis builds the feature combinations based on similarities rather than differences. Discriminant analysis is also different from factor analysis in that it is not an interdependence technique: a distinction between independent variables and dependent variables (also called criterion variables) must be made. LDA works when the measurements made on independent variables for each observation are continuous quantities. When dealing with categorical independent variables, the equivalent technique is discriminant correspondence analysis. Discriminant analysis is used when groups are known a priori (unlike in cluster analysis). Each case must have a score on one or more quantitative predictor measures, and a score on a group measure. In simple terms, discriminant function analysis is classification - the act of distributing things into groups, classes or categories of the same type. == History == The original dichotomous discriminant analysis was developed by Sir Ronald Fisher in 1936. It is different from an ANOVA or MANOVA, which is used to predict one (ANOVA) or multiple (MANOVA) continuous dependent variables by one or more independent categorical variables. Discriminant function analysis is useful in determining whether a set of variables is effective in predicting category membership. == LDA for two classes == Consider a set of observations x → {\displaystyle {\vec {x}}} (also called features, attributes, variables or measurements) for each sample of an object or event with known class y {\displaystyle y} . This set of samples is called the training set in a supervised learning context. The classification problem is then to find a good predictor for the class y {\displaystyle y} of any sample of the same distribution (not necessarily from the training set) given only an observation x → {\displaystyle {\vec {x}}} . LDA approaches the problem by assuming that the conditional probability density functions p ( x → | y = 0 ) {\displaystyle p({\vec {x}}|y=0)} and p ( x → | y = 1 ) {\displaystyle p({\vec {x}}|y=1)} are both the normal distribution with mean and covariance parameters ( μ → 0 , Σ 0 ) {\displaystyle \left({\vec {\mu }}_{0},\Sigma _{0}\right)} and ( μ → 1 , Σ 1 ) {\displaystyle \left({\vec {\mu }}_{1},\Sigma _{1}\right)} , respectively. Under this assumption, the Bayes-optimal solution is to predict points as being from the second class if the log of the likelihood ratios is bigger than some threshold T, so that: 1 2 ( x → − μ → 0 ) T Σ 0 − 1 ( x → − μ → 0 ) + 1 2 ln ⁡ | Σ 0 | − 1 2 ( x → − μ → 1 ) T Σ 1 − 1 ( x → − μ → 1 ) − 1 2 ln ⁡ | Σ 1 | > T {\displaystyle {\frac {1}{2}}({\vec {x}}-{\vec {\mu }}_{0})^{\mathrm {T} }\Sigma _{0}^{-1}({\vec {x}}-{\vec {\mu }}_{0})+{\frac {1}{2}}\ln |\Sigma _{0}|-{\frac {1}{2}}({\vec {x}}-{\vec {\mu }}_{1})^{\mathrm {T} }\Sigma _{1}^{-1}({\vec {x}}-{\vec {\mu }}_{1})-{\frac {1}{2}}\ln |\Sigma _{1}|\ >\ T} Without any further assumptions, the resulting classifier is referred to as quadratic discriminant analysis (QDA). LDA instead makes the additional simplifying homoscedasticity assumption (i.e. that the class covariances are identical, so Σ 0 = Σ 1 = Σ {\displaystyle \Sigma _{0}=\Sigma _{1}=\Sigma } ) and that the covariances have full rank. In this case, several terms cancel: x → T Σ 0 − 1 x → = x → T Σ 1 − 1 x → {\displaystyle {\vec {x}}^{\mathrm {T} }\Sigma _{0}^{-1}{\vec {x}}={\vec {x}}^{\mathrm {T} }\Sigma _{1}^{-1}{\vec {x}}} x → T Σ i − 1 μ → i = μ → i T Σ i − 1 x → {\displaystyle {\vec {x}}^{\mathrm {T} }{\Sigma _{i}}^{-1}{\vec {\mu }}_{i}={{\vec {\mu }}_{i}}^{\mathrm {T} }{\Sigma _{i}}^{-1}{\vec {x}}} because both sides are scalar and transpose to each other ( Σ i {\displaystyle \Sigma _{i}} is Hermitian) and the above decision criterion becomes a threshold on the dot product w → T x → > c {\displaystyle {\vec {w}}^{\mathrm {T} }{\vec {x}}>c} for some threshold constant c, where w → = Σ − 1 ( μ → 1 − μ → 0 ) {\displaystyle {\vec {w}}=\Sigma ^{-1}({\vec {\mu }}_{1}-{\vec {\mu }}_{0})} c = 1 2 w → T ( μ → 1 + μ → 0 ) {\displaystyle c={\frac {1}{2}}\,{\vec {w}}^{\mathrm {T} }({\vec {\mu }}_{1}+{\vec {\mu }}_{0})} This means that the criterion of an input x → {\displaystyle {\vec {x}}} being in a class y {\displaystyle y} is purely a function of this linear combination of the known observations. It is often useful to see this conclusion in geometrical terms: the criterion of an input x → {\displaystyle {\vec {x}}} being in a class y {\displaystyle y} is purely a function of projection of multidimensional-space point x → {\displaystyle {\vec {x}}} onto vector w → {\displaystyle {\vec {w}}} (thus, we only consider its direction). In other words, the observation belongs to y {\displaystyle y} if corresponding x → {\displaystyle {\vec {x}}} is located on a certain side of a hyperplane perpendicular to w → {\displaystyle {\vec {w}}} . The location of the plane is defined by the threshold c {\displaystyle c} . == Assumptions == The assumptions of discriminant analysis are the same as those for MANOVA. The analysis is quite sensitive to outliers and the size of the smallest group must be larger than the number of predictor variables. Multivariate normality: Independent variables are normal for each level of the grouping variable. Homogeneity of variance/covariance (homoscedasticity): Variances among group variables are the same across levels of predictors. Can be tested with Box's M statistic. It has been suggested, however, that linear discriminant analysis be used when covariances are equal, and that quadratic discriminant analysis may be used when covariances are not equal. Independence: Participants are assumed to be randomly sampled, and a participant's score on one variable is assumed to be independent of scores on that variable for all other participants. It has been suggested that discriminant analysis is relatively robust to slight violations of these assumptions, and it has also been shown that discriminant analysis may still be reliable when using dichotomous variables (where multivariate normality is often violated). == Discriminant functions == Discriminant analysis works by creating one or more linear combinations of predictors, creating a new latent variable for each function. These functions are called discriminant functions. The number of functions possible is either N g − 1 {\displaystyle N_{g}-1} where N g {\displaystyle N_{g}} = number of groups, or p {\displaystyle p} (the number of predictors), whichever is smaller. The first function created maximizes the differences between groups on that function. The second function maximizes differences on that function, but also must not be correlated with the previous function. This continues with subsequent functions with the requirement that the new function not be correlated with any of the previous functions. Given group j {\displaystyle j} , with R j {\displaystyle \mathbb {R} _{j}} sets of sample space, there is a discriminant rule such that if x ∈ R j {\displaystyle x\in \mathbb {R} _{j}} , then x ∈ j {\displaystyle x\in j} . Discriminant analysis then, finds “good” regions of R j {\displaystyle \mathbb {R} _{j}} to minimize classification error, therefore leading to a high percent correct classified in the classification table. Each function is given a discriminant score to determine how well it predicts group placement. Structure Corr

Accumulated local effects

Accumulated local effects (ALE) is a machine learning interpretability method. == Concepts == ALE uses a conditional feature distribution as an input and generates augmented data, creating more realistic data than a marginal distribution. It ignores far out-of-distribution (outlier) values. Unlike partial dependence plots and marginal plots, ALE is not defeated in the presence of correlated predictors. It analyzes differences in predictions instead of averaging them by calculating the average of the differences in model predictions over the augmented data, instead of the average of the predictions themselves. == Example == Given a model that predicts house prices based on its distance from city center and size of the building area, ALE compares the differences of predictions of houses of different sizes. The result separates the impact of the size from otherwise correlated features. == Limitations == Defining evaluation windows is subjective. High correlations between features can defeat the technique. ALE requires more and more uniformly distributed observations than PDP so that the conditional distribution can be reliably determined. The technique may produce inadequate results if the data is highly sparse, which is more common with high-dimensional data (curse of dimensionality).

Variational autoencoder

In machine learning, a variational autoencoder (VAE) is an artificial neural network architecture introduced by Diederik P. Kingma and Max Welling in 2013. It is part of the families of probabilistic graphical models and variational Bayesian methods. In addition to being seen as an autoencoder neural network architecture, variational autoencoders can also be studied within the mathematical formulation of variational Bayesian methods, connecting a neural encoder network to its decoder through a probabilistic latent space (for example, as a multivariate Gaussian distribution) that corresponds to the parameters of a variational distribution. Thus, the encoder maps each point (such as an image) from a large complex dataset into a distribution within the latent space, rather than to a single point in that space. The decoder has the opposite function, which is to map from the latent space to the input space, again according to a distribution (although in practice, noise is rarely added during the decoding stage). By mapping a point to a distribution instead of a single point, the network can avoid overfitting the training data. Both networks are typically trained together with the usage of the reparameterization trick, although the variance of the noise model can be learned separately. Although this type of model was initially designed for unsupervised learning, its effectiveness has been proven for semi-supervised learning and supervised learning. == Overview of architecture and operation == A variational autoencoder is a generative model with a prior and noise distribution respectively. Usually such models are trained using the expectation-maximization meta-algorithm (e.g. probabilistic PCA, (spike & slab) sparse coding). Such a scheme optimizes a lower bound of the data likelihood, which is usually computationally intractable, and in doing so requires the discovery of q-distributions, or variational posteriors. These q-distributions are normally parameterized for each individual data point in a separate optimization process. However, variational autoencoders use a neural network as an amortized approach to jointly optimize across data points. In that way, the same parameters are reused for multiple data points, which can result in massive memory savings. The first neural network takes as input the data points themselves, and outputs parameters for the variational distribution. As it maps from a known input space to the low-dimensional latent space, it is called the encoder. The decoder is the second neural network of this model. It is a function that maps from the latent space to the input space, e.g. as the means of the noise distribution. It is possible to use another neural network that maps to the variance, however this can be omitted for simplicity. In such a case, the variance can be optimized with gradient descent. To optimize this model, one needs to know two terms: the "reconstruction error", and the Kullback–Leibler divergence (KL-D). Both terms are derived from the free energy expression of the probabilistic model, and therefore differ depending on the noise distribution and the assumed prior of the data, here referred to as p-distribution. For example, a standard VAE task such as IMAGENET is typically assumed to have a gaussianly distributed noise; however, tasks such as binarized MNIST require a Bernoulli noise. The KL-D from the free energy expression maximizes the probability mass of the q-distribution that overlaps with the p-distribution, which unfortunately can result in mode-seeking behaviour. The "reconstruction" term is the remainder of the free energy expression, and requires a sampling approximation to compute its expectation value. More recent approaches replace Kullback–Leibler divergence (KL-D) with various statistical distances, see "Statistical distance VAE variants" below. == Formulation == From the point of view of probabilistic modeling, one wants to maximize the likelihood of the data x {\displaystyle x} by their chosen parameterized probability distribution p θ ( x ) = p ( x | θ ) {\displaystyle p_{\theta }(x)=p(x|\theta )} . This distribution is usually chosen to be a Gaussian N ( x | μ , σ ) {\displaystyle N(x|\mu ,\sigma )} which is parameterized by μ {\displaystyle \mu } and σ {\displaystyle \sigma } respectively, and as a member of the exponential family it is easy to work with as a noise distribution. Simple distributions are easy enough to maximize, however distributions where a prior is assumed over the latents z {\displaystyle z} results in intractable integrals. Let us find p θ ( x ) {\displaystyle p_{\theta }(x)} via marginalizing over z {\displaystyle z} . p θ ( x ) = ∫ z p θ ( x , z ) d z , {\displaystyle p_{\theta }(x)=\int _{z}p_{\theta }({x,z})\,dz,} where p θ ( x , z ) {\displaystyle p_{\theta }({x,z})} represents the joint distribution under p θ {\displaystyle p_{\theta }} of the observable data x {\displaystyle x} and its latent representation or encoding z {\displaystyle z} . According to the chain rule, the equation can be rewritten as p θ ( x ) = ∫ z p θ ( x | z ) p θ ( z ) d z {\displaystyle p_{\theta }(x)=\int _{z}p_{\theta }({x|z})p_{\theta }(z)\,dz} In the vanilla variational autoencoder, z {\displaystyle z} is usually taken to be a finite-dimensional vector of real numbers, and p θ ( x | z ) {\displaystyle p_{\theta }({x|z})} to be a Gaussian distribution. Then p θ ( x ) {\displaystyle p_{\theta }(x)} is a mixture of Gaussian distributions. It is now possible to define the set of the relationships between the input data and its latent representation as Prior p θ ( z ) {\displaystyle p_{\theta }(z)} Likelihood p θ ( x | z ) {\displaystyle p_{\theta }(x|z)} Posterior p θ ( z | x ) {\displaystyle p_{\theta }(z|x)} Unfortunately, the computation of p θ ( z | x ) {\displaystyle p_{\theta }(z|x)} is expensive and in most cases intractable. To speed up the calculus to make it feasible, it is necessary to introduce a further function to approximate the posterior distribution as q ϕ ( z | x ) ≈ p θ ( z | x ) {\displaystyle q_{\phi }({z|x})\approx p_{\theta }({z|x})} with ϕ {\displaystyle \phi } defined as the set of real values that parametrize q {\displaystyle q} . This is sometimes called amortized inference, since by "investing" in finding a good q ϕ {\displaystyle q_{\phi }} , one can later infer z {\displaystyle z} from x {\displaystyle x} quickly without doing any integrals. In this way, the problem is to find a good probabilistic autoencoder, in which the conditional likelihood distribution p θ ( x | z ) {\displaystyle p_{\theta }(x|z)} is computed by the probabilistic decoder, and the approximated posterior distribution q ϕ ( z | x ) {\displaystyle q_{\phi }(z|x)} is computed by the probabilistic encoder. Parametrize the encoder as E ϕ {\displaystyle E_{\phi }} , and the decoder as D θ {\displaystyle D_{\theta }} . == Evidence lower bound (ELBO) == Like many deep learning approaches that use gradient-based optimization, VAEs require a differentiable loss function to update the network weights through backpropagation. For variational autoencoders, the idea is to jointly optimize the generative model parameters θ {\displaystyle \theta } to reduce the reconstruction error between the input and the output, and ϕ {\displaystyle \phi } to make q ϕ ( z | x ) {\displaystyle q_{\phi }({z|x})} as close as possible to p θ ( z | x ) {\displaystyle p_{\theta }(z|x)} . As reconstruction loss, mean squared error and cross entropy are often used. The Kullback–Leibler divergence D K L ( q ϕ ( z | x ) ∥ p θ ( z | x ) ) {\displaystyle D_{KL}(q_{\phi }({z|x})\parallel p_{\theta }({z|x}))} can be used as a loss function to squeeze q ϕ ( z | x ) {\displaystyle q_{\phi }({z|x})} under p θ ( z | x ) {\displaystyle p_{\theta }(z|x)} . This divergence loss expands to D K L ( q ϕ ( z | x ) ∥ p θ ( z | x ) ) = E z ∼ q ϕ ( ⋅ | x ) [ ln ⁡ q ϕ ( z | x ) p θ ( z | x ) ] = E z ∼ q ϕ ( ⋅ | x ) [ ln ⁡ q ϕ ( z | x ) p θ ( x ) p θ ( x , z ) ] = ln ⁡ p θ ( x ) + E z ∼ q ϕ ( ⋅ | x ) [ ln ⁡ q ϕ ( z | x ) p θ ( x , z ) ] . {\displaystyle {\begin{aligned}D_{KL}(q_{\phi }({z|x})\parallel p_{\theta }({z|x}))&=\mathbb {E} _{z\sim q_{\phi }(\cdot |x)}\left[\ln {\frac {q_{\phi }(z|x)}{p_{\theta }(z|x)}}\right]\\&=\mathbb {E} _{z\sim q_{\phi }(\cdot |x)}\left[\ln {\frac {q_{\phi }({z|x})p_{\theta }(x)}{p_{\theta }(x,z)}}\right]\\&=\ln p_{\theta }(x)+\mathbb {E} _{z\sim q_{\phi }(\cdot |x)}\left[\ln {\frac {q_{\phi }({z|x})}{p_{\theta }(x,z)}}\right].\end{aligned}}} Now, define the evidence lower bound (ELBO): L θ , ϕ ( x ) := E z ∼ q ϕ ( ⋅ | x ) [ ln ⁡ p θ ( x , z ) q ϕ ( z | x ) ] = ln ⁡ p θ ( x ) − D K L ( q ϕ ( ⋅ | x ) ∥ p θ ( ⋅ | x ) ) {\displaystyle L_{\theta ,\phi }(x):=\mathbb {E} _{z\sim q_{\phi }(\cdot |x)}\left[\ln {\frac {p_{\theta }(x,z)}{q_{\phi }({z|x})}}\right]=\ln p_{\theta }(x)-D_{KL}(q_{\phi }({\cdot |x})\parallel p_{\theta }({\cdot |x}))} Maximizing the ELBO θ ∗ , ϕ ∗ = argmax θ , ϕ L θ , ϕ ( x ) {\dis

Visual Expert

Visual Expert is a static code analysis tool, extracting design and technical information from software source code by reverse-engineering, used by programmers for software maintenance, modernization or optimization. It is designed to parse several programming languages at the same time (PL/SQL, Transact-SQL, PowerBuilder...) and analyze cross-language dependencies, in addition to each language's source code. Visual Expert checks source code against hundreds of code inspection rules for vulnerability assessment, bug fix, and maintenance issues. == Features == Cross-references exploration: Impact Analysis, E/R diagrams, call graphs, CRUD matrix, dependency graphs. Software documentation: a documentation generator produces technical documentation and low-level design descriptions. Inspect the code to detect bugs, security vulnerabilities and maintainability issues. Native integration with Jenkins. Reports on duplicate code, unused objects and methods and naming conventions. Calculates software metrics and source lines of code. Code comparison: finds differences between several versions of the same code. Performance analysis: identifies code parts that slow down the application because of their syntax - it extracts statistics about code execution from the database and combines it with the static analysis of the code. == Usage == Visual Expert is used in several contexts: Change impact analysis: evaluating the consequences of a change in the code or in a database. Avoiding negative side effects when evolving a system. Static Application Security Testing (SAST): detecting and removing security issues. Continuous Integration / Continuous Inspection : adding a static code analysis job in a CI/CD workflow to automatically verify the quality and security of a new build when it is released. Program comprehension: helping programmers understand and maintain existing code, or modernize legacy systems. Transferring knowledge of the code, from one programmer to another. Software sizing: calculating the size of an application, or a piece of code, in order to estimate development efforts. Code review: improving the code by finding and removing code smells, dead code, code causing poor performances or violations of coding conventions. == Limitations == As a static code analyzer, Visual Expert is limited to the programming languages supported by its code parsers - Oracle PL/SQL, SQL Server Transact-SQL, PowerBuilder. A preliminary reverse engineering is required. Visual Expert does it automatically, but its duration depends on the size of the code parsed. Users must wait for the parsing completion prior to using the features, or schedule it in advance. They must also allocate sufficient hardware resources to support their volume of code. Visual Expert is based on a client/server architecture: the code analysis is running on a Windows PC - preferably a server. The information extracted from the code is stored in a RDBMS, communicating with a client application installed on the programmer's computer - no web client is available. This requires that the code, the parsers, the RDBMS and the programmers’ computers are connected to the same LAN or VPN. == History == 1995- 1998 - Prog and Doc - Initial version distributed on the French market 2001 - Visual Expert 4.5 2003 - Visual Expert 5 2007 - Visual Expert 5.7 2010 - Visual Expert 6.0 2015 - Visual Expert 2015 - Server component added to schedule code analyses 2016 - Visual Expert 2016 - Oracle PL/SQL code parser, code inventory (lines of code, number of objects…) 2017 - Visual Expert 2017 - SQL Server T-SQL code parser, Code comparison, CRUD matrix 2018 - Visual Expert 2018 - DB Code Performance Analysis, integration with TFS 2019 - Visual Expert 2019 - Generation of E/R diagrams from the code 2020 - Visual Expert 2020 - Object dependency matrix, naming consistency verification, integration with GIT and SVN 2021 - Visual Expert 2021 - Continuous Code Inspection, integration with Jenkins 2022 - Visual Expert 2022 - Support for cloud-based repositories and large volumes of code 2023 - Visual Expert 2023 - Performance tuning for PowerBuilder 2024 - Visual Expert 2024 - New web UI to simplify deployment and use among large teams. 2025 - Visual Expert 2025 - AI-based features to explain code, generate comments, and optimize queries

GeWorkbench

geWorkbench (genomics Workbench) is an open-source software platform for integrated genomic data analysis. It is a desktop application written in the programming language Java. geWorkbench uses a component architecture. As of 2016, there are more than 70 plug-ins available, providing for the visualization and analysis of gene expression, sequence, and structure data. geWorkbench is the Bioinformatics platform of MAGNet, the National Center for the Multi-scale Analysis of Genomic and Cellular Networks, one of the 8 National Centers for Biomedical Computing funded through the NIH Roadmap (NIH Common Fund). Many systems and structure biology tools developed by MAGNet investigators are available as geWorkbench plugins. == Features == Computational analysis tools such as t-test, hierarchical clustering, self-organizing maps, regulatory network reconstruction, BLAST searches, pattern-motif discovery, protein structure prediction, structure-based protein annotation, etc. Visualization of gene expression (heatmaps, volcano plot), molecular interaction networks (through Cytoscape), protein sequence and protein structure data (e.g., MarkUs). Integration of gene and pathway annotation information from curated sources as well as through Gene Ontology enrichment analysis. Component integration through platform management of inputs and outputs. Among data that can be shared between components are expression datasets, interaction networks, sample and marker (gene) sets and sequences. Dataset history tracking - complete record of data sets used and input settings. Integration with 3rd party tools such as GenePattern, Cytoscape, and Genomespace. Demonstrations of each feature described can be found at GeWorkbench-web Tutorials. == Versions == geWorkbench is open-source software that can be downloaded and installed locally. A zip file of the released version Java source is also available. Prepackaged installer versions also exist for Windows, Macintosh, and Linux.