Novell Storage Manager is a system software package released by Novell in 2004 that uses identity, policy and directory events to automate full lifecycle management of file storage for individual users and organizational groups. By tying storage management to an organization's existing identity infrastructure, it has been pointed out, Novell Storage Manager enables the administration of users across all file servers "as a single pool rather than [in] separate independently managed domains." Novell Storage Manager is a component of the Novell File Management Suite. == How It Works == Novell Storage Manager dynamically manages and provisions storage based on user and group events that occur in the directory, including user creations, group assignments, moves, renames, and deletions. When a change happens in the directory that affects a user’s file storage needs or user storage policy, Storage Manager applies the appropriate policy and makes the necessary changes at the file system level to address those storage needs. The following key components comprise Novell Storage Manager's identity and policy-driven state machine architecture: Directory services; Storage policies; Novell Storage Manager event monitors; Novell Storage Manager policy engine; Novell Storage Manager agents; and Action objects. This state machine architecture enables the engine to properly deal with transient waits with directory synchronization issues. It also allows recovery from failures involving network communications, a target server or a server running a component of Storage Manager—including the policy engine itself. If a failure or interruption occurs at any point during operation, Storage Manager will be able to successfully continue the operation from where it was when the interruption occurred. == Reviews == Jon Toigo called Novell Storage Manager "a robust and smart approach to corralling user files... into an organized and efficient management scheme". He also said it was "best in class" of the products he'd reviewed.
Nona-binning
Nona-binning is a pixel binning technique used in high-resolution image sensors, primarily in smartphone cameras. The method is based on merging groups of nine neighbouring pixels arranged in a 3×3 pattern. This configuration allows a sensor with very small individual pixels to increase its effective light sensitivity when operating in low-light conditions, while still maintaining high nominal resolution in bright environments. == Overview == Nona-binning is most commonly implemented in sensors with a resolution of 108 megapixels and higher. As pixel counts grew, the physical dimensions of individual pixels continued to shrink, reducing the amount of light captured by each. The 3×3 binning structure enables a sensor to operate in two modes. In well-lit scenes, each pixel is processed separately, providing the full resolution of the sensor. In darker settings, nine pixels with identical colour filters are combined into a single output unit, increasing signal strength and reducing noise. == Technical principles == Unlike the traditional Bayer colour filter array, which alternates colours on a per-pixel basis, nona-binning uses a grouped layout. The sensor forms blocks of nine pixels with matching colour filters — typically within a Quad Bayer–derived arrangement extended to 3×3 regions. When operating in the binning mode, the sensor aggregates the charge generated by all nine pixels in each block. This increases effective sensitivity but lowers the final image resolution. When lighting conditions allow, the sensor returns to processing pixel data individually. == Applications == Nona-binning is primarily used in: Smartphone photography, particularly in devices equipped with sensors exceeding 100 megapixels. Low-light imaging, where increased sensitivity improves exposure stability and reduces noise. Computational photography systems, such as multi-frame processing and HDR capture. == Related technologies == Nona-binning belongs to the broader group of pixel-binning approaches used in modern sensors. Other implementations include Tetracell, which merges four pixels in a 2×2 block, and hexa-binning, which combines six pixels, though it is less common. All of these methods aim to balance the high nominal resolution of mobile sensors with the need for improved low-light performance.
Environmental informatics
Environmental informatics is the science of information applied to environmental science. As such, it provides the information processing and communication infrastructure to the interdisciplinary field of environmental sciences aiming at data, information and knowledge integration, the application of computational intelligence to environmental data as well as the identification of environmental impacts of information technology. Environmental informatics thus acts as a bridge, providing an interdisciplinary means of analysing, describing and understanding the complex interactions between humans, nature and technology. Since each field of applied computer science has its own subject matter, terminology and methods, specialised disciplines, such as environmental, bio- and geoinformatics have emerged, each of which combines computer science with a specific field of application such as environmental, bio- or geosciences. Environmental informatics, bioinformatics and geoinformatics all deal with computer-based processing of environmental phenomena. However, environmental informatics is the only field that pursues normative goals (e.g., political goals of environmental protection, environmental planning, and sustainability). This also influences the choice of methods. This also distinguishes it from application areas such as numerical weather prediction, which is considered an early and important example of computer simulation of environmental phenomena. The UK Natural Environment Research Council defines environmental informatics as the "research and system development focusing on the environmental sciences relating to the creation, collection, storage, processing, modelling, interpretation, display and dissemination of data and information." Kostas Karatzas defined environmental informatics as the "creation of a new 'knowledge-paradigm' towards serving environmental management needs." Karatzas argued further that environmental informatics "is an integrator of science, methods and techniques and not just the result of using information and software technology methods and tools for serving environmental engineering needs." Environmental informatics emerged in early 1990 in Central Europe. Current initiatives to effectively manage, share, and reuse environmental and ecological data are indicative of the increasing importance of fields like environmental informatics and ecoinformatics to develop the foundations for effectively managing ecological information. Examples of these initiatives are National Science Foundation Datanet projects, DataONE and Data Conservancy. == Subject matter and objectives == The subject of environmental informatics are environmental information systems (EIS). An EIS 'is a computer-based system that integrates and stores data collected about the natural environment and provides powerful methods for accessing and evaluating it.' This allows environmental data to be processed by computers for environmental protection, planning, research and technology. According to Jaeschke and Bossel, environmental informatics has three interrelated objectives: Environmental informatics serves to procure data and information for describing the state and development of the environment. Of particular importance is information that is needed to prevent or limit undesirable changes and to support desirable changes. Based on the evaluation and analysis of data, environmental informatics improves our understanding of the environment and the interactions between nature, technology and society. It thus supports environmentally relevant decisions. This enables the influence of development (system correction), the assessment of the effects and side effects of potential measures, and the creation of tools for the routine planning, implementation and monitoring of measures. == History == The simulation model World3, which formed the basis of the highly acclaimed study The Limits to Growth, is considered the starting point of environmental informatics. It incorporated environmental information, among other things, to calculate scenarios for global development. In the mid-1980s, interest grew in structuring environmental protection as an area of application for computer science. One of the first publications in German was the book Informatik im Umweltschutz. Anwendungen und Perspektiven (Computer science in environmental protection. Applications and perspectives) from 1986. The term 'environmental informatics' did not appear until around 1993, which is why the development of environmental informatics is usually referred to as having taken place in the 1990s. In 1993, the first university chair for environmental informatics was established in Cottbus. In 1994, the anthology Umweltinformatik. Informatikmethoden für Umweltschutz und Umweltforschung (Environmental Informatics: Informatics Methods for Environmental Protection and Environmental Research) was published. The development of environmental informatics was 'primarily initiated by German computer science.' In the English-speaking world, the volume Environmental Informatics was published in 1995, mainly based on the German anthology of 1994. An article in the conference proceedings of the World Computer Congress of the International Federation for Information Processing (IFIP) in Hamburg in 1994 describes the initial situation of environmental informatics as follows: 'On the one hand, we suffer from the huge amount of available data – people sometimes speak of data graveyards – on the other hand, the really relevant data may still be missing.' This statement indicates the need that led to the emergence of environmental informatics as a specialised discipline of applied computer science. Furthermore, the specific characteristics and processing requirements of environmental data necessitated the emergence of environmental informatics. The special features of environmental data include: The data structures required are highly heterogeneous due to specific processes and differing perspectives on environmental aspects (e.g., water protection, emission control, hazardous substances). In addition to the heterogeneity of the data, heterogeneous databases also play a role, as environmental data is often obtained and presented in an interdisciplinary manner. Obligations change frequently as a result of new legislation, whether regional (e.g. state regulations on water protection), national (e.g. federal emission control regulations) or international (e.g. Registration, Evaluation, Authorisation and Restriction of Chemicals|REACH). The objects represented are often multidimensional and, therefore, require complex geometric representation using curves or polygons. It is often necessary to process uncertain, imprecise or incomplete data, which is, for example, the result of extrapolations or forecasts. A new "knowledge paradigm" has emerged to meet the requirements of environmental management. Environmental informatics produces its own concepts, methods and techniques and is not merely the result of using information and communication technology methods and tools to meet environmental requirements. The development of environmental informatics since the 1990s has been significantly influenced by the newly established conferences EnviroInfo, ISESS and ITEE and is documented in the respective proceedings. Aspects of sustainability and sustainable development were increasingly integrated into environmental informatics after 2000, thereby expanding the field. In 2004, the Working Group on Sustainable Information Society of the Gesellschaft für Informatik e. V. (German Informatics Society, GI) published the Memorandum on a Sustainable Information Society, which formulates recommendations for an information society that is compatible with human, social and natural needs. Since 2007, environmental informatics has often been described in more detail as informatics for environmental protection, sustainable development and risk management. The increased focus on sustainability has also contributed to the formation of the research focus Information and Communications Technology for Sustainability (ICT4S) and to the emergence of the international conference ICT4S in 2013. ICT-ENSURE, the European Commission's funding measure for the establishment of a European research area on "ICT for Environmental Sustainability Research" (2008–2010), has also contributed to the structuring of environmental informatics. == Environmental informatics and sustainable development == Efforts to place environmental informatics within the context of sustainable development have been growing since 2000 and were significantly influenced by the Memorandum on a Sustainable Information Society. According to this Memorandum, the information society offers great but unevenly distributed opportunities for education, participation and intercultural understanding. In addition, the Memorandum highlighted the material and energy consumption of inf
Query language
A query language, also known as data query language or database query language (DQL), is a computer language used to make queries in databases and information systems. In database systems, query languages rely on strict theory to retrieve information. A well known example is the Structured Query Language (SQL). == Types == Broadly, query languages can be classified according to whether they are database query languages or information retrieval query languages. The difference is that a database query language attempts to give factual answers to factual questions, while an information retrieval query language attempts to find documents containing information that is relevant to an area of inquiry. Other types of query languages include: Full-text. The simplest query language is treating all terms as bag of words that are to be matched with the postings in the inverted index and where subsequently ranking models are applied to retrieve the most relevant documents. Only tokens are defined in the CFG. Web search engines often use this approach. Boolean. A query language that also supports the use of the Boolean operators AND, OR, NOT. Structured. A language that supports searching within (a combination of) fields when a document is structured and has been indexed using its document structure. Natural language. A query language that supports natural language by parsing the natural language query to a form that can be best used to retrieve relevant documents, for example with Question answering systems or conversational search. == Examples == Attempto Controlled English is a query language that is also a controlled natural language. AQL is a query language for the ArangoDB native multi-model database system. .QL is a proprietary object-oriented query language for querying relational databases; successor of Datalog. CodeQL is the analysis engine used by developers to automate security checks, and by security researchers to perform variant analysis on GitHub. Contextual Query Language (CQL) a formal language for representing queries to information retrieval systems such as web indexes or bibliographic catalogues. Cypher is a query language for the Neo4j graph database. DMX is a query language for data mining models. Datalog is a query language for deductive databases. F-logic is a declarative object-oriented language for deductive databases and knowledge representation. FQL enables you to use a SQL-style interface to query the data exposed by the Graph API. It provides advanced features not available in the Graph API. Gellish English is a language that can be used for queries in Gellish English Databases, for dialogues (requests and responses) as well as for information modeling and knowledge modeling. Gremlin is an Apache Software Foundation graph traversal language for OLTP and OLAP graph systems. GraphQL is a data query language developed by Facebook as an alternate to REST and ad-hoc webservice architectures. HTSQL is a query language that translates HTTP queries to SQL. ISBL is a query language for PRTV, one of the earliest relational database management systems. Jaql is a functional data processing and query language most commonly used for JSON query processing. JPQL is a query language defined as part of Jakarta Persistence (used in Java applications to make queries to a relational DB using entity objects instead of DB tables). jq is a functional programming language often used for processing queries against one or more JSON documents, including very large ones. JSONiq is a declarative query language designed for collections of JSON documents. KQL (Kusto Query Language), a query language by Microsoft used in Azure Data Explorer LDAP is an application protocol for querying and modifying directory services running over TCP/IP. LogiQL is a variant of Datalog and is the query language for the LogicBlox system. M Formula language, a mashup query language used in Microsoft's Power Query. MQL is a cheminformatics query language for a substructure search allowing beside nominal properties also numerical properties. MDX is a query language for OLAP databases. N1QL is a Couchbase's query language finding data in Couchbase Servers. Object Query Language OCL (Object Constraint Language). Despite its name, OCL is also an object query language and an OMG standard. OPath, intended for use in querying WinFS Stores. Poliqarp Query Language is a special query language designed to analyze annotated text. Used in the Poliqarp search engine. PQL is a special-purpose programming language for managing process models based on information about scenarios that these models describe. PRQL PRQL (Pipelined Relational Query Language) is a modern language for transforming data. Consists of a curated set of orthogonal transformations, which are combined together to form a pipeline. PTQL based on relational queries over program traces, allowing programmers to write expressive, declarative queries about program behavior. QUEL is a relational database access language, similar in most ways to SQL. RDQL is a RDF query language. SMARTS is the cheminformatics standard for a substructure search. SPARQL is a query language for RDF graphs. SQL is a well-known query language and data manipulation language for relational databases. XQuery is a query language for XML data sources. XPath is a declarative language for navigating XML documents. YQL is an SQL-like query language created by Yahoo!. Search engine query languages, e.g., as used by Google. or Bing
Aidoc
Aidoc Medical is an Israeli technology company that develops computer-aided simple triage and notification systems. Aidoc has obtained U.S. Food and Drug Administration and CE mark approval for its stroke, pulmonary embolism, cervical fracture, intracranial hemorrhage, intra-abdominal free gas, and incidental pulmonary embolism algorithms. Aidoc algorithms are in use in more than 900 hospitals and imaging centers, including Montefiore Nyack Hospital, LifeBridge Health, LucidHealth, Yale New Haven Hospital, Cedars-Sinai Medical Center, University of Rochester Medical Center, and Sheba Medical Center. == History == Aidoc was founded in 2016 by Elad Walach as the CEO, Michael Braginsky as the CTO and Guy Reiner as the VP. In April 2017, the company raised $7M, led by TLV Partners, and in April 2019, the company raised another $27M, led by Square Peg capital. There have been several additional rounds of funding as well, bringing Aidoc's total investment to $370M as of July 2025. In August 2018, Aidoc gained FDA clearance for its intracranial hemorrhage system, and in May 2019 it received clearance for the pulmonary embolism system. In January 2020, the system for detecting large-vessel occlusions (LVOs) in head CTA examinations obtained FDA clearance. In October 2024, it was reported that Aidoc is working with NVIDIA to develop a framework for deployment and integration of artificial intelligence tools in healthcare. The Blueprint for Resilient Integration and Deployment of Guided Excellence (BRIDGE) is a guideline to facilitate AI adoption in the healthcare industry. == Products and market == Aidoc has developed a suite of artificial intelligence products that flag both time-sensitive and time-consuming (for the radiologist) abnormalities across the body. The algorithms are developed with large quantities of data to provide diagnostic aid for a broad set of pathologies. The company offers an array of algorithms that span across the body, including for intracranial hemorrhage, spine fractures (C, T & L), free air in the abdomen, pulmonary embolism, and more. It developed "Always-on AI", a term coined by Elad Walach that refers to a type of artificial intelligence that is "Always-on—constantly running in the background and automatically analyzing medical imaging data, identifying urgent findings, and sparing radiologists from "drowning" in vast amounts of irrelevant data. Aidoc's solutions cover medical conditions prevalent in all settings (ED/inpatient/outpatient), including level 1 trauma centers, outpatient imaging centers, teleradiology groups and, are set up in over 200 medical centers worldwide. Notable customers include the University of Rochester Medical Center and Global Diagnostics Australia. Aidoc announced in 2024 that its new Clinical AI Reasoning Engine (CARE1) had been submitted for FDA approval. In September 2025 Aidoc received a "Breakthrough Device Designation" from the FDA for a new multi-triage solution that spans numerous acute findings in CT scans. Aidoc's CARE1 foundation model was the basis of the workflow on which the designation was made, enabling simultaneous coverage of multiple pathologies. This new designation allows parallel FDA review of multiple indications under a single submission. In April 2026, Aidoc raised million in a Series E funding round led by Growth Equity at Goldman Sachs Alternatives, with participation from General Catalyst and NVentures. The financing brought the company's total funding to over million. == Clinical Research == A clinical study on Aidoc’ accuracy of deep convolutional neural networks for the detection of pulmonary embolism (PE) on CT pulmonary angiograms (CTPAs) was performed by the University Hospital of Basel and presented at the European Congress of Radiology, showing that the Aidoc algorithm reached 93% sensitivity and 95% specificity. Clinical research has also been performed to test the diagnostic performance of Aidoc's deep learning-based triage system for the flagging of acute findings in abdominal computed tomography (CT) examinations. Overall, the algorithm achieved 93% sensitivity (91/98, 7 false negatives) and 97% specificity (93/96, 3 false-positive) in the detection of acute abdominal findings. Additional clinical research on Aidoc's Intracranial hemorrhage algorithm accuracy was presented at the European Congress of Radiology by Antwerp University Hospital, evaluating the use of its deep learning algorithm for the detection of intracranial hemorrhage on non-contrast enhanced CT of the brain. The University of Washington completed a study on the accuracy of Aidoc's intracranial hemorrhage algorithm.
Biorobotics
Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems. == Cybernetics == Cybernetics focuses on the communication and system of living organisms and machines that can be applied and combined with multiple fields of study such as biology, mathematics, computer science, engineering, and much more. This discipline falls under the branch of biorobotics because of its combined field of study between biological bodies and mechanical systems. Studying these two systems allows for advanced analysis on the functions and processes of each system as well as the interactions between them. === History === Cybernetic theory is a concept that has existed for centuries, dating back to the era of Plato where he applied the term to refer to the "governance of people". The term cybernetique is seen in the mid-1800s used by physicist André-Marie Ampère. The term cybernetics was popularized in the late 1940s to refer to a discipline that touched on, but was separate, from established disciplines, such as electrical engineering, mathematics, and biology. === Science === Cybernetics is often misunderstood because of the breadth of disciplines it covers. In the early 20th century, it was coined as an interdisciplinary field of study that combines biology, science, network theory, and engineering. Today, it covers all scientific fields with system related processes. The goal of cybernetics is to analyze systems and processes of any system or systems in an attempt to make them more efficient and effective. === Applications === Cybernetics is used as an umbrella term so applications extend to all systems related scientific fields such as biology, mathematics, computer science, engineering, management, psychology, sociology, art, and more. Cybernetics is used amongst several fields to discover principles of systems, adaptation of organisms, information analysis and much more. == Genetic engineering == Genetic engineering is a field that uses advances in technology to modify biological organisms. Through different methods, scientists are able to alter the genetic material of microorganisms, plants and animals to provide them with desirable traits. For example, making plants grow bigger, better, and faster. Genetic engineering is included in biorobotics because it uses new technologies to alter biology and change an organism's DNA for their and society's benefit. === History === Although humans have modified genetic material of animals and plants through artificial selection for millennia (such as the genetic mutations that developed teosinte into corn and wolves into dogs), genetic engineering refers to the deliberate alteration or insertion of specific genes to an organism's DNA. The first successful case of genetic engineering occurred in 1973 when Herbert Boyer and Stanley Cohen were able to transfer a gene with antibiotic resistance to a bacterium. === Science === There are three main techniques used in genetic engineering: The plasmid method, the vector method and the biolistic method. ==== Plasmid method ==== This technique is used mainly for microorganisms such as bacteria. Through this method, DNA molecules called plasmids are extracted from bacteria and placed in a lab where restriction enzymes break them down. As the enzymes do this, some develop a rough edge that resembles that of a staircase which is considered 'sticky' and capable of reconnecting. These 'sticky' molecules are inserted into another bacteria where they will connect to the DNA rings with the altered genetic material. ==== Vector method ==== The vector method is considered a more precise technique than the plasmid method as it involves the transfer of a specific gene instead of a whole sequence. In the vector method, a specific gene from a DNA strand is isolated through restriction enzymes in a laboratory and is inserted into a vector. Once the vector accepts the genetic code, it is inserted into the host cell where the DNA will be transferred. ==== Biolistic method ==== The biolistic method is typically used to alter the genetic material of plants. This method embeds the desired DNA with a metallic particle such as gold or tungsten in a high speed gun. The particle is then bombarded into the plant. Due to the high velocities and the vacuum generated during bombardment, the particle is able to penetrate the cell wall and inserts the new DNA into the cell. === Applications === Genetic engineering has many uses in the fields of medicine, research and agriculture. In the medical field, genetically modified bacteria are used to produce drugs such as insulin, human growth hormones and vaccines. In research, scientists genetically modify organisms to observe physical and behavioral changes to understand the function of specific genes. In agriculture, genetic engineering is extremely important as it is used by farmers to grow crops that are resistant to herbicides and to insects such as BTCorn. == Bionics == Bionics is a medical engineering field and a branch of biorobotics consisting of electrical and mechanical systems that imitate biological systems, such as prosthetics and hearing aids. It's a portmanteau that combines biology and electronics. === History === The history of bionics goes as far back in time as ancient Egypt. A prosthetic toe made out of wood and leather was found on the foot of a mummy. The time period of the mummy corpse was estimated to be from around the fifteenth century B.C. Bionics can also be witnessed in ancient Greece and Rome. Prosthetic legs and arms were made for amputee soldiers. In the early 16th century, a French military surgeon by the name of Ambroise Pare became a pioneer in the field of bionics. He was known for making various types of upper and lower prosthetics. One of his most famous prosthetics, Le Petit Lorrain, was a mechanical hand operated by catches and springs. During the early 19th century, Alessandro Volta further progressed bionics. He set the foundation for the creation of hearing aids with his experiments. He found that electrical stimulation could restore hearing by inserting an electrical implant to the saccular nerve of a patient's ear. In 1945, the National Academy of Sciences created the Artificial Limb Program, which focused on improving prosthetics since there were a large number of World War II amputee soldiers. Since this creation, prosthetic materials, computer design methods, and surgical procedures have improved, creating modern-day bionics. === Science === ==== Prosthetics ==== The important components that make up modern-day prosthetics are the pylon, the socket, and the suspension system. The pylon is the internal frame of the prosthetic that is made up of metal rods or carbon-fiber composites. The socket is the part of the prosthetic that connects the prosthetic to the person's missing limb. The socket consists of a soft liner that makes the fit comfortable, but also snug enough to stay on the limb. The suspension system is important in keeping the prosthetic on the limb. The suspension system is usually a harness system made up of straps, belts or sleeves that are used to keep the limb attached. The operation of a prosthetic could be designed in various ways. The prosthetic could be body-powered, externally-powered, or myoelectrically powered. Body-powered prosthetics consist of cables attached to a strap or harness, which is placed on the person's functional shoulder, allowing the person to manipulate and control the prosthetic as he or she deems fit. Externally-powered prosthetics consist of motors to power the prosthetic and buttons and switches to control the prosthetic. Myoelectrically powered prosthetics are new, advanced forms of prosthetics where electrodes are placed on the muscles above the limb. The electrodes will detect the muscle contractions and send electrical signals to the prosthetic to move the prosthetic. The downside to this type of prosthetic is that if the sensors are not placed correctly on the limb then the electrical impulses will fail to move the prosthetic. TrueLimb is a specific brand of prosthetics that uses myoelectrical sensors which enable a person to have control of their bionic limb. ==== Hearing aids ==== Four major components make up the hearing aid: the microphone, the amplifier, the receiver, and the battery. The microphone takes in outside sound, turns that sound to electrical signals, and sends those signals to the amplifier. The amplifier increases the sound and sends that sound to the receiver. The receiver changes the electrical signal back into sound and sends the sound into the ear. Hair cells in the ear will sense the vibrations from the sound, convert the vibrations into nerve signals, and send it to the brain so
Semantic integration
Semantic integration is the process of interrelating information from diverse sources, for example calendars and to do lists, email archives, presence information (physical, psychological, and social), documents of all sorts, contacts (including social graphs), search results, and advertising and marketing relevance derived from them. In this regard, semantics focuses on the organization of and action upon information by acting as an intermediary between heterogeneous data sources, which may conflict not only by structure but also context or value. == Applications and methods == In enterprise application integration (EAI), semantic integration can facilitate or even automate the communication between computer systems using metadata publishing. Metadata publishing potentially offers the ability to automatically link ontologies. One approach to (semi-)automated ontology mapping requires the definition of a semantic distance or its inverse, semantic similarity and appropriate rules. Other approaches include so-called lexical methods, as well as methodologies that rely on exploiting the structures of the ontologies. For explicitly stating similarity/equality, there exist special properties or relationships in most ontology languages. OWL, for example has "owl:equivalentClass", "owl:equivalentProperty" and "owl:sameAs". Eventually system designs may see the advent of composable architectures where published semantic-based interfaces are joined together to enable new and meaningful capabilities. These could predominately be described by means of design-time declarative specifications, that could ultimately be rendered and executed at run-time. Semantic integration can also be used to facilitate design-time activities of interface design and mapping. In this model, semantics are only explicitly applied to design and the run-time systems work at the syntax level. This "early semantic binding" approach can improve overall system performance while retaining the benefits of semantic driven design. == Semantic integration situations == From the industry use case, it has been observed that the semantic mappings were performed only within the scope of the ontology class or the datatype property. These identified semantic integrations are (1) integration of ontology class instances into another ontology class without any constraint, (2) integration of selected instances in one ontology class into another ontology class by the range constraint of the property value and (3) integration of ontology class instances into another ontology class with the value transformation of the instance property. Each of them requires a particular mapping relationship, which is respectively: (1) equivalent or subsumption mapping relationship, (2) conditional mapping relationship that constraints the value of property (data range) and (3) transformation mapping relationship that transforms the value of property (unit transformation). Each identified mapping relationship can be defined as either (1) direct mapping type, (2) data range mapping type or (3) unit transformation mapping type. == KG vs. RDB approaches == In the case of integrating supplemental data source, KG(Knowledge graph) formally represents the meaning involved in information by describing concepts, relationships between things, and categories of things. These embedded semantics with the data offer significant advantages such as reasoning over data and dealing with heterogeneous data sources. The rules can be applied on KG more efficiently using graph query. For example, the graph query does the data inference through the connected relations, instead of repeated full search of the tables in relational database. KG facilitates the integration of new heterogeneous data by just adding new relationships between existing information and new entities. This facilitation is emphasized for the integration with existing popular linked open data source such as Wikidata.org. SQL query is tightly coupled and rigidly constrained by datatype within the specific database and can join tables and extract data from tables, and the result is generally a table, and a query can join tables by any columns which match by datatype. SPARQL query is the standard query language and protocol for Linked Open Data on the web and loosely coupled with the database so that it facilitates the reusability and can extract data through the relations free from the datatype, and not only extract but also generate additional knowledge graph with more sophisticated operations(logic: transitive/symmetric/inverseOf/functional). The inference based query (query on the existing asserted facts without the generation of new facts by logic) can be fast comparing to the reasoning based query (query on the existing plus the generated/discovered facts based on logic). The information integration of heterogeneous data sources in traditional database is intricate, which requires the redesign of the database table such as changing the structure and/or addition of new data. In the case of semantic query, SPARQL query reflects the relationships between entities in a way that aligned with human's understanding of the domain, so the semantic intention of the query can be seen on the query itself. Unlike SPARQL, SQL query, which reflects the specific structure of the database and derived from matching the relevant primary and foreign keys of tables, loses the semantics of the query by missing the relationships between entities. Below is the example that compares SPARQL and SQL queries for medications that treats "TB of vertebra". SELECT ?medication WHERE { ?diagnosis a example:Diagnosis . ?diagnosis example:name “TB of vertebra” . ?medication example:canTreat ?diagnosis . } SELECT DRUG.medID FROM DIAGNOSIS, DRUG, DRUG_DIAGNOSIS WHERE DIAGNOSIS.diagnosisID=DRUG_DIAGNOSIS.diagnosisID AND DRUG.medID=DRUG_DIAGNOSIS.medID AND DIAGNOSIS.name=”TB of vertebra” == Examples == The Pacific Symposium on Biocomputing has been a venue for the popularization of the ontology mapping task in the biomedical domain, and a number of papers on the subject can be found in its proceedings.