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Nanosemantics
Nanosemantics Lab is a Russian IT company specializing in natural language processing (NLP), computer vision (CV), speech technologies (ASR/TTS) and creation of interactive dialog interfaces, particularly chatbots and virtual assistants, based on artificial intelligence (AI). The company uses neural network platforms, including its own-made platform PuzzleLib which works on Russian-made microprocessor architecture Elbrus and Russia-based Astra Linux operating system. The company was founded in 2005 by Igor Ashmanov and Natalya Kaspersky. == Profile == The company was one of the first on Russian market to develop dialog interfaces for different branches of businesses, as well as to support community of AI developers. The company's most demanded product, as for beginning of the 2020s, is the automated "online advisers", functioning as chat bots, made for helping customers with usage of commercial products. In 2009 the company released an online service called iii.ru, where visitors were able to create their own AI-based virtual personalities entitles "infs" (for free). A visitor was able to train its own "inf" and let them chat to other "live" visitors as well with other "infs". More than 2.3 million of "infs" were created and trained by visitors over several years. Nanosemantics Lab maintains its own linguistic programming language for AI development called Dialog Language (DL). Popular social networks and instant messaging services may be used as base platforms. Nanosemantics' AI bots support different types of businesses: banks and financial services, telecommunications, retail, travel and automobile industry, home appliances production, etc. Among its solutions, Nanosemantics lists projects for various companies and institutions, among them VTB, Beeline, MTS, Sberbank, Higher School of Economics, Webmoney, Gazpromneft, Rostelecom, Ford Motors, Ministry of Health of the Russian Federation and others. The company uses the term "inf" for naming its numerous types of chat bots. The term was coined by co-founder Igor Ashmanov, head of Ashmanov & Partners. A 2014 scholarly research at Higher School of Economics, called "Basics of Business Informatics", states that such "infs", when used at business, may lower load on employees, collect statistics useful for understanding market demand and also may increase customer loyalty by providing fast and informative answers due to usage of large databases. The same research describes Nanosemantics' project for Russian branch of Ford Motors company, when AI capabilities were used for promoting the car model Ford Kuga. The research pointed out that within 2 months since beginning, the promo-website conducted 47774 talks of visitors with the specialized "inf", which indicated several hundred thousand of questions and the longest chat lasted for 3 hours 10 minutes. One-year promo campaign showed that 28.6% of people who made pre-orders talked to an "inf". In 2016 Nanosemantics launched a SaaS platform aimed at creating customized virtual assistants by users. The company's flagship product is considered to be Dialog Operating System (DialogOS), a professional corporate platform for creating intellectual voice and textual bots. It has its own linguistic programming language for creation of flexible scenarios and ready-studied neural natural language processing modules that are able to understand human interlocutors. In 2021 the company presented technology called NLab Speech ASR which contains a set of neural-networking algorithms for processing audio signals and analysis of texts that were trained and calibrated using speech-based big data marked up manually. The technology allows speed of processing of data up to "6 real-time factor" and precision values in noisy audio data may exceed 82%. In March 2022 the technology was included in Russia's Joint Registry for Russian Programs for Computers and Databases. As well, another technology was included: NLab Speech TTS, which is text-to-speech system that produces synthesized speech from printed text. == Joint projects == Nanosemantics participates in Ashmanov & Partners' projects related to AI. Since 2014, it helps in development of hardware "personal assistant" called Lexy, a solution similar to Amazon Alexa and the analogues. In August 2019 it was announced that Nanosemantics is going to participate in creation of open operating system for creating automated voice assistants. The project was called SOVA (Smart Open Virtual Assistant) and received investment of 300 million roubles (~$4,6 million) from Russian state-maintained National Technological Initiative. The company maintains long-term partnerships with Skolkovo Innovation Center (resident of IT cluster), branch association "Neuronet" and Yandex. Together with USA-based startup Remedy Logic, Nanosemantics has developed a medical diagnostic system for finding, using AI, spinal pathologies in tomography images of human bodies. Among them: central, foraminal and lateral lumbar stenosis, hernias, arthrosis. The system offers options of treatment. Since August 2021 the company is the resident of Technology Valley of Moscow State University. Also in 2021, Nanosemantics became a member of Committee on Artificial Intelligence within the Russian Association of Software Developers "Native Soft". The company states as one of its missions support of initiatives aimed at preservation and development of the Russian language. In May 2021, together with Pushkin Institute, the company created a chat bot called Phil, that explains to Russian people meaning of different Russian neologisms, and offers synonyms for them. Bot's vocabulary contains more than 500 neologisms, as well the bot can give advice on jargonisms and other types of specific words. Also in 2021, Nanosemanics Lab has signed the first-ever Russian "Codex of ethics of artificial intelligence". It establishes guidelines for ethical behavior of businesses that implement AI-based solutions. === IT contests === The company regularly organizes All-Russian Turing Test competitions for IT developers. Some of these events are co-organized with Microsoft. During the competitions, judges randomly choose virtual interlocutor and have a short conversation with them. They have to determine if a human or a machine is talking to them. An interlocutor may be either a bot or its human creator or operator. The results are measured in per cent of judges that were successfully convinced by a machine that it was a human. In 2021 Nanosemantics took part in federal project "Artificial Intelligence" by National Technological Initiative. In December 2021 the company together with state enterprise "Resource Center of Universal Design and Rehabilitation Technologies" (RCUD-RT) held an all-Russian hackathon aimed at development of AI solutions for medicine. During 3 days, participants created several training programs for patients with speech disorders. In April 2022, another hackathon by Nanosemantics was held together with MIREA – Russian Technological University. Students were participating and trying to generate algorithms for voice deepfakes. 17 teams contested in creation of software that generated artificial voice of a certain person. == Recognition == Since its foundation, Nanosemantics Lab has received a number of recognitions and awards. Among them are several professional ROTOR awards for the website iii.ru (created in 2009). The website gives the general public the means to create and train virtual assistants, which can then be used on a website or integrated into social networks. In 2013, a virtual assistant called Dana, created for Beeline Kazakhstan, was awarded with professional prize "Crystal Headset" in nomination "the best applying of technology". In 2015, the RBTH international media service included Nanosemantics in its list of "Top 50 Startups" in Russia. In 2016, the company received Russian state-maintained award called Runet Prize in two nominations: "State and Society" and "Technology and Innovation". In 2021, in Velikiy Novgorod, Nanosemantics team has won a hackathon aimed at finding means of discovering corruption schemes in Russian laws. In February 2022 the company won another contest by National Technological Initiative, called "Prochtenie", aimed at creation of AI systems for checking schoolchildren's school essays. The Nanosemantics team was awarded 20 million rubles for "overcoming technological barrier" in contest dedicated to English language, and 12 million for 1st place in special nomination "Structure" in Russian-language essay contest.
Thompson sampling
Thompson sampling, named after William R. Thompson, is a heuristic for choosing actions that address the exploration–exploitation dilemma in the multi-armed bandit problem. It consists of choosing the action that maximizes the expected reward with respect to a randomly drawn belief. == Description == Consider a set of contexts X {\displaystyle {\mathcal {X}}} , a set of actions A {\displaystyle {\mathcal {A}}} , and rewards in R {\displaystyle \mathbb {R} } . The aim of the player is to play actions under the various contexts, such as to maximize the cumulative rewards. Specifically, in each round, the player obtains a context x ∈ X {\displaystyle x\in {\mathcal {X}}} , plays an action a ∈ A {\displaystyle a\in {\mathcal {A}}} and receives a reward r ∈ R {\displaystyle r\in \mathbb {R} } following a distribution that depends on the context and the issued action. The elements of Thompson sampling are as follows: a likelihood function P ( r | θ , a , x ) {\displaystyle P(r|\theta ,a,x)} ; a set Θ {\displaystyle \Theta } of parameters θ {\displaystyle \theta } of the distribution of r {\displaystyle r} ; a prior distribution P ( θ ) {\displaystyle P(\theta )} on these parameters; past observations triplets D = { ( x ; a ; r ) } {\displaystyle {\mathcal {D}}=\{(x;a;r)\}} ; a posterior distribution P ( θ | D ) ∝ P ( D | θ ) P ( θ ) {\displaystyle P(\theta |{\mathcal {D}})\propto P({\mathcal {D}}|\theta )P(\theta )} , where P ( D | θ ) {\displaystyle P({\mathcal {D}}|\theta )} is the likelihood function. Thompson sampling consists of playing the action a ∗ ∈ A {\displaystyle a^{\ast }\in {\mathcal {A}}} according to the probability that it maximizes the expected reward; action a ∗ {\displaystyle a^{\ast }} is chosen with probability ∫ I [ E ( r | a ∗ , x , θ ) = max a ′ E ( r | a ′ , x , θ ) ] P ( θ | D ) d θ , {\displaystyle \int \mathbb {I} \left[\mathbb {E} (r|a^{\ast },x,\theta )=\max _{a'}\mathbb {E} (r|a',x,\theta )\right]P(\theta |{\mathcal {D}})d\theta ,} where I {\displaystyle \mathbb {I} } is the indicator function. In practice, the rule is implemented by sampling. In each round, parameters θ ∗ {\displaystyle \theta ^{\ast }} are sampled from the posterior P ( θ | D ) {\displaystyle P(\theta |{\mathcal {D}})} , and an action a ∗ {\displaystyle a^{\ast }} chosen that maximizes E [ r | θ ∗ , a ∗ , x ] {\displaystyle \mathbb {E} [r|\theta ^{\ast },a^{\ast },x]} , i.e. the expected reward given the sampled parameters, the action, and the current context. Conceptually, this means that the player instantiates their beliefs randomly in each round according to the posterior distribution, and then acts optimally according to them. In most practical applications, it is computationally onerous to maintain and sample from a posterior distribution over models. As such, Thompson sampling is often used in conjunction with approximate sampling techniques. == History == Thompson sampling was originally described by Thompson in 1933. It was subsequently rediscovered numerous times independently in the context of multi-armed bandit problems. A first proof of convergence for the bandit case has been shown in 1997. The first application to Markov decision processes was in 2000. A related approach (see Bayesian control rule) was published in 2010. In 2010 it was also shown that Thompson sampling is instantaneously self-correcting. Asymptotic convergence results for contextual bandits were published in 2011. Thompson Sampling has been widely used in many online learning problems including A/B testing in website design and online advertising, and accelerated learning in decentralized decision making. A Double Thompson Sampling (D-TS) algorithm has been proposed for dueling bandits, a variant of traditional MAB, where feedback comes in the form of pairwise comparison. == Relationship to other approaches == === Probability matching === Probability matching is a decision strategy in which predictions of class membership are proportional to the class base rates. Thus, if in the training set positive examples are observed 60% of the time, and negative examples are observed 40% of the time, the observer using a probability-matching strategy will predict (for unlabeled examples) a class label of "positive" on 60% of instances, and a class label of "negative" on 40% of instances. === Bayesian control rule === A generalization of Thompson sampling to arbitrary dynamical environments and causal structures, known as Bayesian control rule, has been shown to be the optimal solution to the adaptive coding problem with actions and observations. In this formulation, an agent is conceptualized as a mixture over a set of behaviours. As the agent interacts with its environment, it learns the causal properties and adopts the behaviour that minimizes the relative entropy to the behaviour with the best prediction of the environment's behaviour. If these behaviours have been chosen according to the maximum expected utility principle, then the asymptotic behaviour of the Bayesian control rule matches the asymptotic behaviour of the perfectly rational agent. The setup is as follows. Let a 1 , a 2 , … , a T {\displaystyle a_{1},a_{2},\ldots ,a_{T}} be the actions issued by an agent up to time T {\displaystyle T} , and let o 1 , o 2 , … , o T {\displaystyle o_{1},o_{2},\ldots ,o_{T}} be the observations gathered by the agent up to time T {\displaystyle T} . Then, the agent issues the action a T + 1 {\displaystyle a_{T+1}} with probability: P ( a T + 1 | a ^ 1 : T , o 1 : T ) , {\displaystyle P(a_{T+1}|{\hat {a}}_{1:T},o_{1:T}),} where the "hat"-notation a ^ t {\displaystyle {\hat {a}}_{t}} denotes the fact that a t {\displaystyle a_{t}} is a causal intervention (see Causality), and not an ordinary observation. If the agent holds beliefs θ ∈ Θ {\displaystyle \theta \in \Theta } over its behaviors, then the Bayesian control rule becomes P ( a T + 1 | a ^ 1 : T , o 1 : T ) = ∫ Θ P ( a T + 1 | θ , a ^ 1 : T , o 1 : T ) P ( θ | a ^ 1 : T , o 1 : T ) d θ {\displaystyle P(a_{T+1}|{\hat {a}}_{1:T},o_{1:T})=\int _{\Theta }P(a_{T+1}|\theta ,{\hat {a}}_{1:T},o_{1:T})P(\theta |{\hat {a}}_{1:T},o_{1:T})\,d\theta } , where P ( θ | a ^ 1 : T , o 1 : T ) {\displaystyle P(\theta |{\hat {a}}_{1:T},o_{1:T})} is the posterior distribution over the parameter θ {\displaystyle \theta } given actions a 1 : T {\displaystyle a_{1:T}} and observations o 1 : T {\displaystyle o_{1:T}} . In practice, the Bayesian control amounts to sampling, at each time step, a parameter θ ∗ {\displaystyle \theta ^{\ast }} from the posterior distribution P ( θ | a ^ 1 : T , o 1 : T ) {\displaystyle P(\theta |{\hat {a}}_{1:T},o_{1:T})} , where the posterior distribution is computed using Bayes' rule by only considering the (causal) likelihoods of the observations o 1 , o 2 , … , o T {\displaystyle o_{1},o_{2},\ldots ,o_{T}} and ignoring the (causal) likelihoods of the actions a 1 , a 2 , … , a T {\displaystyle a_{1},a_{2},\ldots ,a_{T}} , and then by sampling the action a T + 1 ∗ {\displaystyle a_{T+1}^{\ast }} from the action distribution P ( a T + 1 | θ ∗ , a ^ 1 : T , o 1 : T ) {\displaystyle P(a_{T+1}|\theta ^{\ast },{\hat {a}}_{1:T},o_{1:T})} . === Upper-confidence-bound (UCB) algorithms === Thompson sampling and upper-confidence bound algorithms share a fundamental property that underlies many of their theoretical guarantees. Roughly speaking, both algorithms allocate exploratory effort to actions that might be optimal and are in this sense "optimistic". Leveraging this property, one can translate regret bounds established for UCB algorithms to Bayesian regret bounds for Thompson sampling or unify regret analysis across both these algorithms and many classes of problems.
International Aerial Robotics Competition
The International Aerial Robotics Competition (IARC) is a university-based robotics competition held on the campus of the Georgia Institute of Technology, currently hosted by RoboNation. Since 1991, collegiate teams with the backing of industry and government have fielded autonomous flying robots in an attempt to perform missions requiring robotic behaviors not previously exhibited by a flying machine. The term “aerial robotics” was coined by competition creator Robert Michelson in 1990 to describe a new class of small highly intelligent flying machines. Successive years of competition saw these aerial robots grow from vehicles that could barely maintain themselves in the air, to automatons which are self-stable, self-navigating, and able to interact with their environment. The goal of the competition has been to provide a reason for the state-of-the-art of aerial robotics to move forward. Challenges have been geared towards producing advances. From 1991 through 2009, six missions were proposed. Each involved fully autonomous robotic behavior undemonstrated at the time. In October 2013 a seventh mission was proposed. It was the first to involve interaction between aerial robots and multiple ground robots. In 2016, the competition and its creator were recognized during the Georgia legislative session in the form of a senate resolution as the longest running aerial robotics competition in the world. == History == === First mission === The initial mission to move a metallic disc from one side of an arena to the other was seen by many as almost impossible. The college teams improved their entries over the next two years when the competition saw its first autonomous takeoff, flight, and landing by a team from the Georgia Institute of Technology. In 1995, a team from Stanford University was able to acquire a single disk and move it from one side of the arena to the other in a fully autonomous flight—half. === Second mission === The competition mission was toughened and made less abstract by requiring teams to search for a toxic waste dump, map the location of partially buried randomly oriented toxic waste drums, identify the contents of each drum from the hazard labels on the outside of each drum, and bring a sample back from one of the drums. In 1996, a team from the Massachusetts Institute of Technology and Boston University, with backing from Draper Labs, created a small fully autonomous flying robot that repeatedly and correctly mapped the location of all five of the toxic waste drums, and correctly identified the contents of two from the air, completing approximately seventy five percent of the mission. The following year, an aerial robot developed by a team from Carnegie Mellon University completed the entire mission. === Third mission === The third mission began in 1998. It was a search and rescue mission requiring fully autonomous robots to take off, fly to a disaster area and search amid fires, broken water mains, clouds of toxic gas, and rubble. The scenario was recreated at the U.S. Department of Energy's Hazardous Material Management and Emergency Response (HAMMER) training facility. Because of the realism of the scenario, animatrons were used instead of human actors to simulate survivors incapable of extracting themselves from the disaster area. An aerial robot from Germany's Technische Universität Berlin was able to detect and avoid all of the obstacles, identify all the dead on the ground and the survivors (distinguishing between the two based on movement), and relay pictures of the survivors along with their locations back to first responders who would attempt a rescue. This mission was completed in 2000. === Fourth mission === The fourth mission was initiated in 2001. It involved three scenarios requiring the same autonomous behavior: a hostage rescue mission where a submarine 3 kilometers off the coast must send an aerial robot to find a coastal city, identify the embassy where hostages are being held, locate valid openings in the embassy building, enter (or send in a sensor probe/subvehicle) and relay pictures of the hostages 3 km to the submarine prior to mounting an amphibious assault on the embassy to free the hostages; the discovery of an ancient mausoleum where a virus had killed the archaeological team, who had radioed that an important and undocumented tapestry was hanging inside, with 15 minutes to send an autonomous aerial robot to find the mausoleum, enter it (or send in a sensor probe/subvehicle) and relay pictures of the tapestry back prior to the destruction of the mausoleum and its contents; and an explosion at a nuclear reactor facility where scientists must send in an aerial robot to find the operating reactor building, enter the building (or send in a sensor probe/subvehicle) and relay pictures of the control panels to determine if a melt-down is imminent. All three missions involved the same elements of ingress, locating, identification, entry, and relaying pictures within 15 minutes. It was conducted at the U.S. Army's Fort Benning Soldier Battle Lab using the McKenna MOUT (Military Operations on Urban Terrain) site. The fourth mission was completed in 2008 with 27 teams who had demonstrated each of the required aerial robotic behaviors, except being able to demonstrate these behaviors in under 15 minutes—a feat considered by the judges to be inevitable given more time, and therefore no longer a significant challenge. Thus the fourth mission was terminated, $80,000 in awards distributed, and the fifth mission established. === Fifth mission === The fifth mission picked up where the fourth mission left off by demonstrating the fully autonomous aerial robotic behaviors necessary to rapidly negotiate the confined internal spaces of a structure once it has been penetrated by an air vehicle. The nuclear reactor complex explosion scenario of the fourth mission was used as the backdrop for the fifth mission. The fifth mission required a fully autonomous aerial vehicle to penetrate the structure and negotiate the more complex interior space containing hallways, small rooms, obstacles, and dead ends in order to search for a designated target without the aid of global-positioning navigational aids, and relay pictures back to a monitoring station some distance from the structure. The First Symposium on Indoor Flight Issues was held in conjunction with this 2009 IARC event. === Sixth mission === The sixth mission began in 2010 as an extension of the fifth mission theme of autonomous indoor flight behavior, however it demanded more advanced behaviors than were possible by any aerial robot extant in 2010. This espionage mission involved covertly stealing a flash drive from a particular room in a building and depositing an identical drive to avoid detection of the theft. The 2010 Symposium on Indoor Flight Issues was held concurrently at the University of Puerto Rico - Mayagüez during the 20th anniversary competition. === Seventh mission === The seventh mission began in 2014 demanding more advanced behaviors than were possible by any aerial robot extant in 2014. A single autonomous aerial robot had to herd up to 10 autonomous ground robot targets across one designated end of a 20m x 20m (65.62 feet x 65.62 feet) arena in under 10 minutes. The arena had neither walls for SLAM mapping nor GPS availability. Techniques such as optical flow or optical odometry were possible solutions to navigation within the arena. Collisions with obstacle ground robots ended the run with no score. The autonomous aerial robots interacted with the ground robots in the following way: if an aerial robot touched the ground robot on top, the ground robot would turn clockwise 45°. If the aerial robot blocked its forward motion by landing in front of it, the ground robot would reverse direction. Ground robots that feely escaped the arena, counted against the aerial robot's overall score, so the autonomous aerial robots had to decide which ground robots were in imminent danger of crossing any boundary except the designated one, and redirect them toward the designated boundary.Zhejiang University was the overall winner of Mission 7, of 52 teams from 12 nations entered as competitors. === Eighth mission === In 2018, the 8th mission was announced. Mission 8 focused on non-electronic human-machine interaction for the first time, with four aerial robots assisting humans to complete tasks that one person could not independently accomplish. The gist of mission 8 involved a swarm of autonomous aerial robots working with a human to achieve a task in the presence of hostile "Sentry aerial robots" which were trying to impede the human. In 2018, the inaugural year of mission 8, the American Venue was held on the campus of the Georgia Institute of Technology in Atlanta, Georgia, and the Asia/Pacific Venue was conducted at Beihang University in Beijing China. The following year, Mission 8 was successfully completed in Kunming China at the Yunnan Innovation
Fuzzy finite element
The fuzzy finite element method combines the well-established finite element method with the concept of fuzzy numbers, the latter being a special case of a fuzzy set. The advantage of using fuzzy numbers instead of real numbers lies in the incorporation of uncertainty (on material properties, parameters, geometry, initial conditions, etc.) in the finite element analysis. One way to establish a fuzzy finite element (FE) analysis is to use existing FE software (in-house or commercial) as an inner-level module to compute a deterministic result, and to add an outer-level loop to handle the fuzziness (uncertainty). This outer-level loop comes down to solving an optimization problem. If the inner-level deterministic module produces monotonic behavior with respect to the input variables, then the outer-level optimization problem is greatly simplified, since in this case the extrema will be located at the vertices of the domain.
EnQuire
Enquire is a web-based software application used as a platform for project, contract and grant management, as well as reporting and planning. Initially designed for the specific business requirements of the Australian Government, Queensland Government and Queensland Regional Bodies to manage natural resource projects, Enquire has since seen adoption outside of this industry and user segment. The use of Enquire by Natural Resource Management bodies within Queensland has been cited as a reason for the improved efficiency, quantity and quality of reporting. Technically, Enquire is implemented as a Java application built on a MySQL database. Enquire is hosted and supported under the software as a service model by Tactiv Pty Ltd. == History == The system was first released in 2005 under the name ViSTA NRM Online, proactively changing its name to Enquire in 2007 to avoid possible confusion with Windows Vista, which was being released at the time. In 2012, the Enquire project and support team was commercialized as its own company called Tactiv Pty Ltd. Tactiv is based predominantly in Brisbane, Australia. Tactiv has continued to develop and grow the Enquire Grant, Contract and Project management solution, releasing a new platform in 2017. Since commercialization, Tactiv has grown its client base to include government and non-government organizations such as foundations and not-for-profit organizations. == Functionality == The functionality of Enquire can be broken down into 5 key lifecycle solutions, all fully integrated and supported by over 40 feature rich and configurable modules: Grant Management Contract Management Project Portfolio Management Procurement Management Relationship Management The system provides its platform to meet the needs of "off the shelf" customers looking for a ready to use best practice option as well as a fully configurable option for specific requirements. The system offers a client supplier portal for external applicants or suppliers, a management portal for internal team usage and an administration portal for clients to manage access, roles, information, and other configurations. Key functional modules include: Online authoring and publishing for forms and applications Workflows Project Tracking Performance Reporting Financial Reporting Stakeholder Communication Budget management Document Management Milestone tracking Payments and Variations Management KPI tracking and Impact reporting The Enquire system is used to report against the Queensland Government's Q2 Coast and Country Program and parts of the Australian Government's Caring for our Country program. There is also a strategic planning module, which provides functionality to manage core-business administration and reporting requirements, whilst providing visibility of key activities and their alignment against organizational goals and strategic objectives. The systems architecture supports a range of implementation models with the capacity to manage one-to-one, one-to-many and many-to-many relationships between investors and investees. Under the usage model within Queensland, Regional Bodies use Enquire to load project contracts and report against these online. The regional bodies also record output, target and financial information in Enquire, which can then be used for operational purposes including financial, performance and target reporting. == External Audit == The Australian National Audit Office Audit Report No.21 2007–08 undertook a case study on Enquire. It noted: "The Queensland Department of Environment and Resource Management has developed the first integrated web-based system [Enquire] to manage performance information about Natural Resource Management activities in Queensland." Four of Queensland's 14 regional bodies commented on Enquire through the ANAO's survey. These four regional bodies indicated that Enquire offers a means of consistent reporting at the State level.
Big Mechanism
Big Mechanism is a $45 million DARPA research program, begun in 2014, aimed at developing software that will read cancer research papers, integrate them into a cancer model and frame new hypotheses by the end of 2017 through the automated collection of big data and integrating across various disciplines such as knowledge-based NLP, curation and ontology, systems and mathematical biology by reading research abstracts and papers to extract pieces of causal mechanisms. == Ras gene == The program focuses on mutations in the Ras gene family, which underlie some one-third of human cancers. Currently, a rough road map shows interaction sequences among proteins affecting cell replication and death. However, the causal relations are poorly understood. == Plan == The program is to occur in three stages. The first is to read literature and convert it into formal representations. Second is to integrate the knowledge into computational models. Third is to produce experimentally testable explanations and predictions. Research teams are developing four separate systems targeting all three tasks. In February 2015, an evaluation meeting reviewed progress on the first stage. Multiple tasks were considered. One was extraction of experimental procedure details and evaluating statements such as "we demonstrate" and "we suggest." Another worked to map sentence meaning and relationships. The best machine-reading system extracted 40% of relevant information from a small corpus and correctly determined how each passage related to the model. The second stage is to become active in summer 2015, when members attempt to produce a single reference model. The third stage is the most challenging, because the artificial intelligence community has had limited success at developing hypothesis generators. Molecular biology may be more amenable, because most domain knowledge is technical and available in written form.