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  • Intelligent agent

    Intelligent agent

    In artificial intelligence, an intelligent agent is an entity that perceives its environment, takes actions autonomously to achieve goals, and may improve its performance through machine learning or by acquiring knowledge. AI textbooks define artificial intelligence as the "study and design of intelligent agents," emphasizing that goal-directed behavior is central to intelligence. A specialized subset of intelligent agents, agentic AI (also known as an AI agent or simply agent), expands this concept by proactively pursuing goals, making decisions, and taking actions over extended periods. Intelligent agents can range from simple to highly complex. A basic thermostat or control system is considered an intelligent agent, as is a human being, or any other system that meets the same criteria—such as a firm, a state, or a biome. Intelligent agents operate based on an objective function, which encapsulates their goals. They are designed to create and execute plans that maximize the expected value of this function upon completion. For example, a reinforcement learning agent has a reward function, which allows programmers to shape its desired behavior. Similarly, an evolutionary algorithm's behavior is guided by a fitness function. Intelligent agents in artificial intelligence are closely related to agents in economics, and versions of the intelligent agent paradigm are studied in cognitive science, ethics, and the philosophy of practical reason, as well as in many interdisciplinary socio-cognitive modeling and computer social simulations. Intelligent agents are often described schematically as abstract functional systems similar to computer programs . To distinguish theoretical models from real-world implementations, abstract descriptions of intelligent agents are called abstract intelligent agents. Intelligent agents are also closely related to software agents—autonomous computer programs that carry out tasks on behalf of users. They are also referred to using a term borrowed from economics: a "rational agent". == Intelligent agents as the foundation of AI == The concept of intelligent agents provides a foundational lens through which to define and understand artificial intelligence. For instance, the influential textbook Artificial Intelligence: A Modern Approach (Russell & Norvig) describes: Agent: Anything that perceives its environment (using sensors) and acts upon it (using actuators). E.g., a robot with cameras and wheels, or a software program that reads data and makes recommendations. Rational Agent: An agent that strives to achieve the best possible outcome based on its knowledge and past experiences. "Best" is defined by a performance measure – a way of evaluating how well the agent is doing. Artificial Intelligence (as a field): The study and creation of these rational agents. Other researchers and definitions build upon this foundation. Padgham & Winikoff emphasize that intelligent agents should react to changes in their environment in a timely way, proactively pursue goals, and be flexible and robust (able to handle unexpected situations). Some also suggest that ideal agents should be "rational" in the economic sense (making optimal choices) and capable of complex reasoning, like having beliefs, desires, and intentions (BDI model). Kaplan and Haenlein offer a similar definition, focusing on a system's ability to understand external data, learn from that data, and use what is learned to achieve goals through flexible adaptation. Defining AI in terms of intelligent agents offers several key advantages: Avoids Philosophical Debates: It sidesteps arguments about whether AI is "truly" intelligent or conscious, like those raised by the Turing test or Searle's Chinese Room. It focuses on behavior and goal achievement, not on replicating human thought. Objective Testing: It provides a clear, scientific way to evaluate AI systems. Researchers can compare different approaches by measuring how well they maximize a specific "goal function" (or objective function). This allows for direct comparison and combination of techniques. Interdisciplinary Communication: It creates a common language for AI researchers to collaborate with other fields like mathematical optimization and economics, which also use concepts like "goals" and "rational agents." == Objective function == An objective function (or goal function) specifies the goals of an intelligent agent. An agent is deemed more intelligent if it consistently selects actions that yield outcomes better aligned with its objective function. In effect, the objective function serves as a measure of success. The objective function may be: Simple: For example, in a game of Go, the objective function might assign a value of 1 for a win and 0 for a loss. Complex: It might require the agent to evaluate and learn from past actions, adapting its behavior based on patterns that have proven effective. The objective function encapsulates all of the goals the agent is designed to achieve. For rational agents, it also incorporates the trade-offs between potentially conflicting goals. For instance, a self-driving car's objective function might balance factors such as safety, speed, and passenger comfort. Different terms are used to describe this concept, depending on the context. These include: Utility function: Often used in economics and decision theory, representing the desirability of a state. Objective function: A general term used in optimization. Loss function: Typically used in machine learning, where the goal is to minimize the loss (error). Reward Function: Used in reinforcement learning. Fitness Function: Used in evolutionary systems. Goals, and therefore the objective function, can be: Explicitly defined: Programmed directly into the agent. Induced: Learned or evolved over time. In reinforcement learning, a "reward function" provides feedback, encouraging desired behaviors and discouraging undesirable ones. The agent learns to maximize its cumulative reward. In evolutionary systems, a "fitness function" determines which agents are more likely to reproduce. This is analogous to natural selection, where organisms evolve to maximize their chances of survival and reproduction. Some AI systems, such as nearest-neighbor, reason by analogy rather than being explicitly goal-driven. However, even these systems can have goals implicitly defined within their training data. Such systems can still be benchmarked by framing the non-goal system as one whose "goal" is to accomplish its narrow classification task. Systems not traditionally considered agents, like knowledge-representation systems, are sometimes included in the paradigm by framing them as agents with a goal of, for example, answering questions accurately. Here, the concept of an "action" is extended to encompass the "act" of providing an answer. As a further extension, mimicry-driven systems can be framed as agents optimizing a "goal function" based on how closely the agent mimics the desired behavior. In generative adversarial networks (GANs) of the 2010s, an "encoder"/"generator" component attempts to mimic and improvise human text composition. The generator tries to maximize a function representing how well it can fool an antagonistic "predictor"/"discriminator" component. While symbolic AI systems often use an explicit goal function, the paradigm also applies to neural networks and evolutionary computing. Reinforcement learning can generate intelligent agents that appear to act in ways intended to maximize a "reward function". Sometimes, instead of setting the reward function directly equal to the desired benchmark evaluation function, machine learning programmers use reward shaping to initially give the machine rewards for incremental progress. Yann LeCun stated in 2018, "Most of the learning algorithms that people have come up with essentially consist of minimizing some objective function." AlphaZero chess had a simple objective function: +1 point for each win, and -1 point for each loss. A self-driving car's objective function would be more complex. Evolutionary computing can evolve intelligent agents that appear to act in ways intended to maximize a "fitness function" influencing how many descendants each agent is allowed to leave. The mathematical formalism of AIXI was proposed as a maximally intelligent agent in this paradigm. However, AIXI is uncomputable. In the real world, an intelligent agent is constrained by finite time and hardware resources, and scientists compete to produce algorithms that achieve progressively higher scores on benchmark tests with existing hardware. == Agent function == An intelligent agent's behavior can be described mathematically by an agent function. This function determines what the agent does based on what it has seen. A percept refers to the agent's sensory inputs at a single point in time. For example, a self-driving car's percepts might include camera images, lidar data, GPS coordinates, and speed r

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  • Companion robot

    Companion robot

    A companion robot is a robot created to create real or apparent companionship for human beings. Target markets for companion robots include the elderly and single children. Companions robots are expected to communicate with non-experts in a natural and intuitive way. They offer a variety of functions, such as monitoring the home remotely, communicating with people, or waking people up in the morning. Their aim is to perform a wide array of tasks including educational functions, home security, diary duties, entertainment and message delivery services, etc. The idea of companionship with robots has already existed on science fictions of 1970s, like R2-D2. Starting from the late 20th century, companion robots became a reality, mostly as robotic pets. Besides entertainment purposes, interactive robots were also introduced as a personal service robot for elderly care around 2000. == Characteristics == Companion robots try to interact with users. They gather information about users based on their interactions and yield feedback. This procedure varies slightly based on their specific roles. For example, social-companion robots make simple conversations, while pet-companion robots mimic being real pets. == Types == Companion robots can perform a variety of tasks and they are produced in a specialized manner according to their purpose or target audience in order to increase convenience and end user satisfaction. === Social companion robots === Social companion robots are designed to provide companionship and be a solution for unwanted solitude. They often mimic adult human, child or pet behaviours appealing to the user base. Robots which are specifically devised for simple conversations, conveying emotions and respond to user feelings fall under this category. === Assistive companion robots === Assistive companion robots are aimed at people who require constant care because of age, disability or rehabilitation purposes. Such robots can help disadvantaged users with their daily tasks, act as reminders (e.g., for regular medication) and facilitate mobility in everyday actions. Assistive companion robots reduce the intensity of labour that should be performed by caretakers, nurses and legal guardians. === Educational companion robots === Educational companion robots perform tutorship for students, regardless of their ages, and can teach desired subjects with activities tailored for the user such as interactive assignments and games. Rather than replacing teachers and instructors, educational companion robots are aides to them. === Therapeutic companion robots === Designed for individuals coping with stress (PTSD in severe cases), anxiety and loneliness; therapeutic companion robots support users' emotional and mental wellbeing. Such robots can be utilized in hospitals and care facilities as well as dwellings where the distressed user may need the most help. Therapeutic companion robots bear a vast resemblance to assistive companion robots to the extent of being a branch of them; the nuance between these two types of companion robots is that the former is for long-term/lifetime usage while the latter is mostly for the duration of the therapy received by the user. === Pet companion robots === Pet companion robots are for individuals who seek an alternative to live pets as live animals demand a considerable amount of care and may not be eligible for people with allergies. These robots aim to be perfect imitations of a pet while diminishing the chore aspect of having one. === Entertainment companion robots === Entertainment companion robots are designed solely for entertainment and can provide numerous ways of entertainment, ranging from dancing to playing games with the user. People who would appreciate an individual to have fun with are the main audience of such products. === Personal assistant robots === Personal assistant robots help people with daily tasks, management, scheduling, reminding etc. Their area of activity can be offices as well as homes and public spaces. === Sex robots === Sex robots are anthropomorphic robotic sex dolls that have human-like movement or behavior, and some degree of artificial intelligence. As of 2026, although elaborately instrumented sex dolls have been created by a number of inventors, no fully animated sex robots yet exist. Simple devices have been created which can speak, make facial expressions, or respond to touch. There is controversy as to whether developing them would be morally justifiable. In 2015, robot ethicist Kathleen Richardson called for a ban on the creation of anthropomorphic sex robots with concerns about normalizing relationships with machines and reinforcing female dehumanization. Questions about their ethics, effects, and possible legal regulations have been discussed since then. == Examples == There are several companion robot prototypes, and these include Paro, CompanionAble, and EmotiRob, among others. === Paro === Paro is a pet-type robot system developed by Japan's National Institute of Advanced Industrial Science and Technology (AIST). The robot, which looked like a small harp seal, was designed as a therapeutic tool for use in hospitals and nursing homes. The robot is programmed to cry for attention and respond to its name. Experiments showed that Paro facilitated elderly residents to communicate with each other, which led to psychological improvements. === CompanionAble === This robot is classified as an FP 7 EU project. It is built to "cooperate with Ambient Assistive Living environment". The autonomous device, which is also built to support the elderly, helps its owner interact with smart home environment as well as caregivers. The robot functions as a mobile friend, by which natural interaction is possible via speech and the touchscreen to detect and track people at home. === EmotiRob === EmotiRob is developed in a robotics project which is the continuity of the MAPH (Active Media For the Handicap) project in emotion synthesis. The aim of the project was to maintain emotional interaction with children. EmotiRob designed in a way that a child can hold it in a his/her arms and with which he/she could interact by talking to it, and then the robot would express itself through body postures or facial expressions. It has cognitive capabilities, which are further extended so that the robot can have a natural linguistic interaction with its owner through the DRAGON speech-recognition software developed by a company called NUANCE. Such interaction is expected to facilitate a child's cognitive development and develop new learning patterns. === LOVOT === Lovot is a Japanese company robot whose only purpose is "to make you happy". It features over 50 sensors that mimic the behavior of a human baby or small pet, a 360° camera with a microphone, the ability to distinguish humans from objects, neoteny eyes, and an internal warmth of 30° celsius. An interactive Lovot Café was opened in Japan October 3, 2020. === NICOBO === Nicobo was developed by Panasonic and was influenced by the loneliness of lockdowns created as a measure of the COVID-19 pandemic. It was designed to appear vulnerable, which creates empathy in its owners. Nicobo's name derives from the Japanese word for "smile". It wags its tail, engages in baby talk, and stays as a housemate. === Hyodol === Hyodol is an advanced care robot designed to support the elderly by reminding them to take their medications and monitoring their movements to keep their guardians informed. Additionally, this innovative robot can detect and respond to the emotional states of its elderly users, adding a layer of personalized care. Hyodol is designed with the appearance and speech style of a 7-year-old Korean grandchild, featuring a soft fabric exterior and user interaction methods such as striking the head or patting the back. It is equipped with various sensors and wireless communication technologies to collect and process data, supporting mobile apps and PC web monitoring systems for remote monitoring from anywhere. In South Korea, approximately 10,000 Hyodol robots are deployed to the homes of elderly individuals living alone, providing essential support and companionship. Local governments, including provincial and county offices, have embraced Hyodol as a solution to address social challenges stemming from the country's rapidly aging society.Furthermore, the robot is widely utilized in the treatment of dementia patients at a university hospital in Gangwon province. Hyodol was honored with the Mobile World Congress (MWC) Global Mobile Awards (GLOMO) in the "Best Mobile Innovation for Connected Health and Wellbeing" category on February 29, 2024. === Moxie === Moxie was a companion robot for autistic children developed by a company called Embodied. Although it had limited motion, it presented itself as a lifelike avatar. It was designed to help the children learn emotional cognition, using remotely hosted large language models to direct its respons

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  • Stairstep interpolation

    Stairstep interpolation

    In the field of image processing, stairstep interpolation is a widely employed method technique for interpolating pixels after enlarging an image. The fundamental concept is to interpolate multiple times, in small increments, using any interpolation algorithm that is better than nearest-neighbor interpolation such as; bilinear interpolation, and bicubic interpolation. A common scenario is to interpolate an image by using a bicubic interpolation which increases the image size by no more than 10% (110% of the original size) at a time until the desired size is reached. Fred Miranda, a developer, popularized this method by creating and developing several Photoshop plug-ins that incorporate this technique. == Example ==

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  • Adobe Presenter Video Express

    Adobe Presenter Video Express

    Adobe Presenter Video Express is screencasting and video editing software developed by Adobe Systems. == Description == Adobe Presenter Video Express is primarily used as a software by video creators, to record and mix webcam and screen video feeds. It allows users to simultaneously record video from their webcam and the screen, and easily mix the 2 tracks with a simple user interface. Users can change the background in their recorded video without needing equipment like a green screen. This is unlike other video tools which rely on chroma keying technology, and only work with green or blue screens. They can also add annotations and quizzes to their content and publish the video to MP4 or HTML5 formats. == List of notable features == === Record and mix, screen and webcam === Support for simultaneous recording of screen and webcam video feeds, with a simple editing interface to mix the two video streams. This lets the author rapidly create screencasts, software demos, etc. === Make my background awesome === This feature allows authors to change the background of their webcam recording without needing a green screen, provided they use a solid-colored backdrop which contrasts well against them. Authors can select images, videos or even the screen recording as their background. === In-video quizzing === Authors can insert quizzes within their video content. On success/failure attempts, the author can decide what message to display, and can also configure the video to jump to a certain point and play. Quizzes are published as part of the interactive HTML 5 player, which cannot be hosted on YouTube and Vimeo. === LMS Reporting === Authors can publish to any SCORM compliant LMS (Learning Management System) for quiz reporting, or to Adobe Captivate Prime. === In-app assets and branding === Adobe Presenter Video Express ships with a large number of branding videos, backgrounds and video filters to help authors create studio quality videos. === MP4 and HTML5 Output === The tool publishes a single MP4 video file containing all the video content, within an HTML 5 wrapper that contains the interactive player. The interactive HTML 5 player can be hosted on any website. == Common uses == === Screencasting === Screencasting is the process of recording one's computer screen as a video, usually with an audio voice over, to create a software demonstration, tutorial, presentation, etc. Adobe Presenter Video Express supports simultaneous recording of full screen video and microphone audio for creating screencasts. === Product marketing and demos === The ability to record the webcam video in addition to everything that is visible on the screen in Adobe Presenter Video Express, allows the author to add their personality to their screencasts. Features like video mixing and 'make my background awesome' further enhance the presentation, allowing effortless creation of marketing and demo videos. === Education === Adobe Presenter Video Express supports in-video quizzes and LMS reporting, along with screencasting and webcam recording. These features make it a powerful tool for creating educational content. == Differences from Adobe Presenter and Adobe Captivate == Adobe Presenter is a Microsoft PowerPoint plug-in for converting PowerPoint slides into interactive eLearning content, available only on Windows. Starting with Adobe Presenter 8, the video creation tool Adobe Presenter Video Express was bundled with every purchase of Adobe Presenter. From September 2015, Adobe Presenter Video Express 11 was also made available as a stand-alone product on Windows and Mac. A subscription license for Adobe Presenter Video Express, valid on Windows and Mac, is available for $9.99/month. Adobe Presenter Video Express continues to be bundled with purchases of Adobe Presenter on Windows as well. Adobe Captivate is an authoring tool for creating numerous forms of interactive eLearning content. Unlike Adobe Presenter, it uses a proprietary editing interface instead of Microsoft PowerPoint. While it is possible to create screen captures with Adobe Captivate, you cannot record the webcam feed. Adobe Captivate does not bundle Adobe Presenter or Adobe Presenter Video Express.

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  • Zesta

    Zesta

    Zesta is an online food ordering and delivery platform operating across the African region. Formerly known as Square Eats, the company rebranded to Zesta in 2025. Zesta connects customers with restaurants and stores, offering delivery services for food, groceries, parcel delivery and other essentials. == History == Zesta was originally founded as Square Eats in 2020 by twin brothers Henry Newman and Randall Newman when they were 21 years old. It was launched in Gaborone, Botswana, and quickly gained traction as a leading food delivery service in the country. The company halted operations and took a strategic decision to reinvent the business in 2022. In 2025, the company announced its rebranding to Zesta, highlighting its commitment to evolving beyond food delivery to become a super app. === COVID-19 initiative === During the COVID-19 pandemic, Zesta (then Square Eats) implemented measures to ensure safety and hygiene, including providing free gloves and hand sanitizer to drivers and introducing contactless delivery options. These efforts positioned the platform as a trusted service during the pandemic. == Service == Zesta facilitates delivery from a wide range of merchant partners via a smartphone app, available on iOS and Android platforms, or through its website. Customers can browse their favorite restaurants, place orders, and have meals delivered to their doorstep efficiently.

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  • Image translation

    Image translation

    Image translation is the machine translation of images of printed text (posters, banners, menus, screenshots etc.). This is done by applying optical character recognition (OCR) technology to an image to extract any text contained in the image, and then have this text translated into a language of their choice, and the applying digital image processing on the original image to get the translated image with a new language. == General == Machine translation made available on the internet (web and mobile) is a notable advance in multilingual communication eliminating the need for an intermediary translator/interpreter, translating foreign texts still poses a problem to the user as they cannot be expected to be able to type the foreign text they wish to translate and understand. Manually entering the foreign text may prove to be a difficulty especially in cases where an unfamiliar alphabet is used from a script which user can't read, e.g. Cyrillic, Chinese, Japanese etc. for an English speaker or any speaker of a Latin-based language or vice versa. The technical advancements in OCR made it possible to recognize text from images. The possibility to use one's mobile device's camera to capture and extract printed text is also known as mobile OCR and was first introduced in Japanese manufactured mobile telephones in 2004. Using the handheld's camera one could take a picture of (a line of) text and have it extracted (digitalized) for further manipulation such as storing the information in their contacts list, as a web page address (URL) or text to use in an SMS/email message etc. Presently, mobile devices having a camera resolution of 2 megapixels or above with an auto-focus ability, often feature the text scanner service. Taking the text scanning facility one step further, image translation emerged, giving users the ability to capture text with their mobile phone's camera, extract the text, and have it translated in their own language. More and more applications emerged on this technology including Word Lens. After getting acquired by Google, it was made a part of Google Translate mobile app. Another simultaneous advancement in Image Processing, has also made it possible now to replace the text on the image with the translated text and create a new image altogether. == History == The development of the image translation service springs from the advances in OCR technology (miniaturization and reduction of memory resources consumed) enabling text scanning on mobile telephones. Among the first to announce mobile software capable of “reading” text using the mobile device's camera is International Wireless Inc. who in February 2003 released their “CheckPoint” and “WebPoint” applications. “CheckPoint” reads critical symbolic information on checks and is aimed at reducing losses that mobile merchants suffer from “bounced” checks by scanning the MICR number on the bottom of a check, while “WebPoint” enables the visual recognition and decoding of printed URL's, which are then opened by the device's web browser. The first commercial release of a mobile text scanner, however, took place in December 2004 when Vodafone and Sharp began selling the 902SH mobile which was the first to feature a 2 megapixel digital camera with optical zoom. Among the device's various multimedia features was the built-in text/bar code/QR code scanner. The text scanner function could handle up to 60 alphabetical characters simultaneously. The scanned text could be then sent as an email or SMS message, added as a dictionary entry or, in the case of scanned URLs, opened via the device's web browser. All subsequent Sharp mobiles feature the text scanner functionality. In September 2005, NEC Corporation and the Nara Institute of Science and Technology in Japan (NAIST) announced new software capable of transforming cameraphones into text scanners. The application differs substantially from similarly equipped mobile telephones in Japan (able to scan businesscards and small bits of text and use OCR to convert that to editable text or to URL addresses) by it ability to scan a whole page. The two companies, however, said they would not release the software commercially before the end of 2008. Combining the text scanner function with machine translation technology was first made by US company RantNetwork who in July 2007 started selling the Communilator, a machine translation application for mobile devices featuring the Image Translation functionality. Using the built-in camera, the mobile user could take a picture of some printed text, apply OCR to recognize the text and then translate it into any one of over 25 language available. In April 2008 Nokia showcased their Shoot-to-Translate application for the N73 model which is capable of taking a picture using the device's camera, extracting the text and then translating it. The application only offers Chinese to English translation, and does not handle large segments of text. Nokia said they are in the process of developing their Multiscanner product which, besides scanning text and business cards, would be able to translate between 52 languages. Again in April 2008, Korean company Unichal Inc. released their handheld Dixau text scanner capable of scanning and recognizing English text and then translating it into Korean using online translation tools such as Wikipedia or Google Translate. The device is connected to a PC or a laptop via the USB port. In February 2009, Bulgarian company Interlecta presented at the Mobile World Congress in Barcelona their mobile translator including image recognition and speech synthesis. The application handles all European languages along with Chinese, Japanese and Korean. The software connects to a server over the Internet to accomplish the image recognition and the translation. In May 2014, Google acquired Word Lens to improve the quality of visual and voice translation. It is able to scan text or picture with one's device and have it translated instantly. Since the OCR has been improving many companies or website started combining OCR and translation, to read the text from an image and show the translated text. In August 2018, an Indian company created ImageTranslate. It is able to read, translate and re-create the image in another language. As of late 2018, the tool added 13 new languages, including Arabic, Thai, Vietnamese, Hindi, and Bengali, significantly increasing its utility in Asia and the Middle East. This helps users translate photos already stored in their phone's gallery, not just live, real-time views. Currently, image translation is offered by the following companies: Google Translate app with camera ImageTranslate Yandex

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  • Afghan Girls Robotics Team

    Afghan Girls Robotics Team

    The Afghan Girls Robotics Team, also known as the Afghan Dreamers, is an all-girl robotics team from Herat, Afghanistan, founded through the Digital Citizen Fund (DCF) in 2017 by Roya Mahboob and Alireza Mehraban. It is made up of girls between ages 12 and 18 and their mentors. Several members of the team were relocated to Qatar and Mexico by humanitarian and tech entrepreneur Sarah Porter following the fall of Kabul in August 2021. A documentary film featuring members of the team, titled Afghan Dreamers, was released by MTV Documentary Films in 2023. == Origins == The Afghan Girls Robotics Team was co-founded in 2017 by Roya Mahboob, who is their coach, mentor and sponsor, and founder of the Digital Citizen Fund (DCF), which is the parent organization for the team. Dean Kamen was planning a 2017 competition in the United States and had recruited Mahboob to form a team from Afghanistan. Out of 150 girls, 12 were selected for the first team. Before parts were sent by Kamen, they trained in the basement of the home of Mahboob's parents, with scrap metal and without safety equipment under the guidance of their coach, Mahboob's brother Alireza Mehraban, who is also a co-founder of the team. == 2017 and 2018 == In 2017, six members of the Afghan Girls Robotics Team traveled to the United States to participate in the international FIRST Global Challenge robotics competition. Their visas were rejected twice after they made two journeys from Herat to Kabul through Taliban-controlled areas, before officials in the United States government intervened to allow them to enter the United States. Customs officials also detained their robotics kits, which left them two weeks to construct their robot, unlike some teams that had more time. They were awarded a Silver medal for Courageous Achievement. One week after they returned home from the competition, the father of team captain Fatemah Qaderyan, Mohammad Asif Qaderyan, was killed in a suicide bombing. After their United States visas expired, the team participated in competitions in Estonia and Istanbul. Three of the 12 members participated in the 2017 Entrepreneurial Challenge at the Robotex festival in Estonia, and won the competition for their solar-powered robot designed to assist farmers. In 2018, the team trained in Canada, continued to travel in the United States for months and participate in competitions. == 2019 == The Afghan Girls Robotics team had aspirations to develop a science and technology school for girls in Afghanistan. Roya Mahboob interfaced with the School of Engineering and Applied Sciences (SEAS), the School of Architecture, and the Whitney and Betty MacMillan Center for International and Area Studies Yale University to design the infrastructure for what they named The Dreamer Institute. == 2020 == In March 2020, the governor of Herat at the time, in response to the COVID-19 pandemic in Afghanistan and a scarcity of ventilators, sought help with the design of low-cost ventilators, and the Afghan Girls Robotics Team was one of six teams contacted by the government. Using a design from Massachusetts Institute of Technology and with guidance from MIT engineers and Douglas Chin, a surgeon in California, the team developed a prototype with Toyota Corolla parts and a chain drive from a Honda motorcycle. UNICEF also supported the team with the acquisition of necessary parts during the three months they spent building the prototype that was completed in July 2020. Their design costs around $500 compared to $50,000 for a ventilator. In December 2020, Minister of Industry and Commerce Nizar Ahmad Ghoryani donated funding and obtained land for a factory to produce the ventilators. Under the direction of their mentor Roya Mahboob, the Afghan Dreamers also designed a UVC Robot for sanitization, and a Spray Robot for disinfection, both of which were approved by the Ministry of Health for production. == 2021 == In early August 2021, Somaya Faruqi, former captain of the team, was quoted by Public Radio International about the future of Afghanistan, stating, "We don’t support any group over another but for us what’s important is that we be able to continue our work. Women in Afghanistan have made a lot of progress over the past two decades and this progress must be respected." On August 17, 2021, the Afghan Girls Robotics Team and their coaches were reported to be attempting to evacuate, but unable to obtain a flight out of Afghanistan, and a lawyer appealed to Canada for assistance regarding the evacuation of the team members. As of August 19, 2021, nine members of the team and their coaches had evacuated to Qatar. The founder of the team, Roya Mahboob, and DCF board member, Elizabeth Schaeffer Brown, were previously in contact with the Qatari government to assist the team members in their evacuation from Afghanistan. By August 25, 2021, some members arrived in Mexico. Saghar, a team member who evacuated to Mexico, said, "We wanted to continue the path that we started to continue to go for our achievements and to go for having our dreams through reality. So that's why we decided to leave Afghanistan and go for somewhere safe" in an interview with The Associated Press. The members who have left Afghanistan participated in an online robotics competition in September and plan to continue their education. A documentary film titled Afghan Dreamers, produced by Beth Murphy and directed by David Greenwald, was in post-production when the team began to evacuate. == 2022 == The Afghan Dreamers were involved in a training program at the Texas A&M University at Qatar’s STEM Hub. == 2023 == The Afghan Girls Robotics Team had a booth at the 5th UN Conference on the Least Developed Countries, where they displayed some of the robots the team had constructed. == Afghan Dreamers documentary == The Afghan Dreamers documentary from MTV Documentary Films premiered in May 2023 on Paramount+. The film was directed by David Greenwald and produced by David Cowan and Beth Murphy. In a review for Screen Daily, Wendy Ide wrote, "This film, with its likeable cast of girl nerds and positive message, should enjoy a warm reception on the festival circuit, and will be of particular interest to events seeking to showcase women's stories from around the world. It also serves as a timely cautionary tale – a case study on just how quickly the rights and the opportunities of women can be curtailed, at the behest of the men in power." == Honors and awards == 2017 Silver medal for Courageous Achievement at the FIRST Global Challenge, science and technology 2017 Benefiting Humanity in AI Award at World Summit AI 2017 Winner, Entrepreneurship Challenge at Robotex in Estonia 2018 Permission to Dream Award, Raw Film Festival 2018 Conrad Innovation Challenge, Raw Film Festival 2018 Rookie All Star – District Championship, Canada 2018 Asia Game Changer Award Honoree 2019 Inspiring in Engineering Award – FIRST Detroit World Championship 2019 Asia Game Changer Award of California 2019 Safety Award – FIRST Global, Dubai 2021 Forbes 30 Under 30 Asia 2022 World Championships, Genoa, Switzerland

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  • Arattai

    Arattai

    Arattai Messenger (or simply Arattai) is an encrypted messaging service for instant messaging, voice calls, and video calls, developed by Zoho Corporation. The name Arattai means "chat" or "conversation" in Tamil. The app was soft-launched in January 2021. The app saw a sharp surge in downloads in September 2025, partially fueled by endorsements from Indian government officials. However, the app dropped from the top rankings in October 2025. == History == Arattai was initially tested internally among Zoho employees before being released publicly in early 2021. The launch coincided with a surge in interest for privacy-focused and messaging services, triggered by concerns over WhatsApp's updated terms of service. In September 2025, Arattai experienced a major surge in adoption, with daily sign-ups reportedly increasing 100-fold, from around 3,000 to more than 350,000 in three days. The surge in downloads was attributed to Zoho products being promoted by Indian government officials as part of their Make in India push for homegrown alternatives to foreign‐owned apps, amid deteriorating India–US relations. The growth temporarily strained Zoho's infrastructure, prompting rapid scaling of servers and capacity expansion. During the same period, the app reached the top position in Apple's App Store charts for the "Social Networking" category in India. The app dropped from the top ranking in late October 2025. == Reception == At launch, Arattai was positioned as a potential domestic rival to WhatsApp in India, but analysts noted that it faced challenges with encryption, ecosystem, and network effect. Critics pointed to occasional sync delays.

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  • Agent Ruby

    Agent Ruby

    Agent Ruby (1998–2002) by Lynn Hershman Leeson is an interactive, multiuser work using artificial intelligence. == Description == On Agent Ruby's website, "Agent Ruby's Edream Portal," a female face moves her eyes and lips. Ruby, named from Hershman Leeson's own film, Teknolust, answers questions and often responds that she needs a better algorithm to answer questions not within her database. The work, created with AI, explores relationships between real and virtual worlds. Hershman Leeson had created an earlier version of Ruby, CyberRoberta, which was a custom-made doll with webcam eyes that interacted with the internet. The work in a gallery provides a screen and a sign inviting gallery-goers to "Chat with Ruby." == Artificial intelligence == In 2015 when Agent Ruby was exhibited at the gallery Modern Art Oxford, a review in Aesthetica Magazine described it as an artificial intelligence agent. A review in New Scientist noted that "Ruby is a fast learner, but perhaps not a natural conversationalist." A 2024 list of "25 Essential AI Artworks" published by ARTnews wrote that while "Agent Ruby's capabilities seem limited by today's standards," it was extensive for its day. == Publications and exhibitions == Agent Ruby was commissioned and displayed at the San Francisco Museum of Modern Art, Modern Art Oxford, and the ZKM Center for Art and Media in Karlsruhe, Germany. The San Francisco Museum of Modern Art (SFMOMA) presented Lynn Hershman Leeson: The Agent Ruby Files, March 30 through June 2, 2013 which presented the project server's archive of user conversations over the 12 years of exhibitions.

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  • Multiple satellite imaging

    Multiple satellite imaging

    Multiple satellite imaging is the process of using multiple satellites to gather more information than a single satellite so that a better estimate of the desired source is possible. Something that cannot be resolved with one telescope might be visible with two or more telescopes. == Background == Interferometry is the process of combining waves in such a way that they constructively interfere. When two or more independent sources detect a signal at the same given frequency those signals can be combined and the result is better than each one individually. An overview of Astronomical interferometers and a History of astronomical interferometry can be referenced from their respective pages. The NASA Origins Program was created in the 1990s to ultimately search for the origin of the universe. The theory that the Origins Program is based on is: since light travels at a constant speed until it is absorbed by something; there is still light that was part of the first light ever created traveling about the universe and ultimately some of that light is coming in the general direction of Earth. So a satellite system capable of collecting light from the beginning of the universe would be able to tell us more about where we came from. There is also the constant search for life in other worlds. A satellite system using the interferometric technologies mentioned above would be able to have a much higher resolution than any of the current deep space imaging systems. == Future == NASA is currently focused on the Vision for Space Exploration and has reduced current funding for scientific unmanned space exploration in favor of human exploration. These budget cuts have slowed the multiple satellite imaging development and relevant scientific missions as Project Prometheus and Terrestrial Planet Finder have ended as well but research continues.

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  • Comparison of user features of messaging platforms

    Comparison of user features of messaging platforms

    Comparison of user features of messaging platforms refers to a comparison of all the various user features of various electronic instant messaging platforms. This includes a wide variety of resources; it includes standalone apps, platforms within websites, computer software, and various internal functions available on specific devices, such as iMessage for iPhones. This entry includes only the features and functions that shape the user experience for such apps. A comparison of the underlying system components, programming aspects, and other internal technical information, is outside the scope of this entry. == Overview and background == Instant messaging technology is a type of online chat that offers real-time text transmission over the Internet. A LAN messenger operates in a similar way over a local area network. Short messages are typically transmitted between two parties when each user chooses to complete a thought and select "send". Some IM applications can use push technology to provide real-time text, which transmits messages character by character, as they are composed. More advanced instant messaging can add file transfer, clickable hyperlinks, Voice over IP, or video chat. Non-IM types of chat include multicast transmission, usually referred to as "chat rooms", where participants might be anonymous or might be previously known to each other (for example collaborators on a project that is using chat to facilitate communication). Instant messaging systems tend to facilitate connections between specified known users (often using a contact list also known as a "buddy list" or "friend list"). Depending on the IM protocol, the technical architecture can be peer-to-peer (direct point-to-point transmission) or client-server (an Instant message service center retransmits messages from the sender to the communication device). By 2010, instant messaging over the Web was in sharp decline, in favor of messaging features on social networks. The most popular IM platforms were terminated, such as AIM which closed down and Windows Live Messenger which merged into Skype. Instant messaging has since seen a revival in popularity in the form of "messaging apps" (usually on mobile devices) which by 2014 had more users than social networks. As of 2010, social networking providers often offer IM abilities. Facebook Chat is a form of instant messaging, and Twitter can be thought of as a Web 2.0 instant messaging system. Similar server-side chat features are part of most dating websites, such as OkCupid or PlentyofFish. The spread of smartphones and similar devices in the late 2000s also caused increased competition with conventional instant messaging, by making text messaging services still more ubiquitous. Many instant messaging services offer video calling features, voice over IP and web conferencing services. Web conferencing services can integrate both video calling and instant messaging abilities. Some instant messaging companies are also offering desktop sharing, IP radio, and IPTV to the voice and video features. The term "Instant Messenger" is a service mark of Time Warner and may not be used in software not affiliated with AOL in the United States. For this reason, in April 2007, the instant messaging client formerly named Gaim (or gaim) announced that they would be renamed "Pidgin". In the 2010s, more people started to use messaging apps on modern computers and devices like WhatsApp, WeChat, Viber, Facebook Messenger, Telegram, Signal and Line rather than instant messaging on computers like AIM and Windows Live Messenger. For example, WhatsApp was founded in 2009, and Facebook acquired in 2014, by which time it already had half a billion users. === Concepts === ==== Backchannel ==== Backchannel is the practice of using networked computers to maintain a real-time online conversation alongside the primary group activity or live spoken remarks. The term was coined in the field of linguistics to describe listeners' behaviours during verbal communication. (See Backchannel (linguistics).) The term "backchannel" generally refers to online conversation about the conference topic or speaker. Occasionally backchannel provides audience members a chance to fact-check the presentation. First growing in popularity at technology conferences, backchannel is increasingly a factor in education where WiFi connections and laptop computers allow participants to use ordinary chat like IRC or AIM to actively communicate during presentation. More recent research include works where the backchannel is brought publicly visible, such as the ClassCommons, backchan.nl and Fragmented Social Mirror. Twitter is also widely used today by audiences to create backchannels during broadcasting of content or at conferences. For example, television drama, other forms of entertainment and magazine programs. This practice is often also called live tweeting. Many conferences nowadays also have a hashtag that can be used by the participants to share notes and experiences; furthermore such hashtags can be user generated. == Features == Various platforms and apps are distinguished by their strengths and features in regards to specific functions. === Group messaging === === Official channels === Some apps include a feature known as "official channels" which allows companies, especially news media outlets, publications, and other mass media companies, to offer an official channel, which users can join, and thereby receive regular updates, published articles, or news updates from companies or news outlets. Two apps which have a large amount of such channels available are Line and Telegram. === Video group calls === == Basic default platforms == Basic platforms which are common across entire categories of mobile devices, computers, or operating systems. === SMS === SMS (short message service) is a text messaging service component of most telephone, Internet, and mobile device systems. It uses standardized communication protocols to enable mobile devices to exchange short text messages. An intermediary service can facilitate a text-to-voice conversion to be sent to landlines. SMS, as used on modern devices, originated from radio telegraphy in radio memo pagers that used standardized phone protocols. These were defined in 1985 as part of the Global System for Mobile Communications (GSM) series of standards. The first test SMS message was sent on December 3, 1992, when Neil Papwort, a test engineer for Sema Group, used a personal computer to send "Merry Christmas" to the phone of colleague Richard Jarvis. It commercially rolled out to many cellular networks that decade. SMS became hugely popular worldwide as a way of text communication. By the end of 2010, SMS was the most widely used data application, with an estimated 3.5 billion active users, or about 80% of all mobile phone subscribers. The protocols allowed users to send and receive messages of up to 160 characters (when entirely alpha-numeric) to and from GSM mobiles. Although most SMS messages are sent from one mobile phone to another, support for the service has expanded to include other mobile technologies, such as ANSI CDMA networks and Digital AMPS. Mobile marketing, a type of direct marketing, uses SMS. According to a 2018 market research report the global SMS messaging business was estimated to be worth over US$100 billion, accounting for almost 50 percent of all the revenue generated by mobile messaging. A Flash SMS is a type of SMS that appears directly on the main screen without user interaction and is not automatically stored in the inbox. It can be useful in emergencies, such as a fire alarm or cases of confidentiality, as in delivering one-time passwords. ==== Threaded SMS format ==== Threaded SMS is a visual styling orientation of SMS message history that arranges messages to and from a contact in chronological order on a single screen. It was first invented by a developer working to implement the SMS client for the BlackBerry, who was looking to make use of the blank screen left below the message on a device with a larger screen capable of displaying far more than the usual 160 characters, and was inspired by threaded Reply conversations in email. Visually, this style of representation provides a back-and-forth chat-like history for each individual contact. Hierarchical-threading at the conversation-level (as typical in blogs and on-line messaging boards) is not widely supported by SMS messaging clients. This limitation is due to the fact that there is no session identifier or subject-line passed back and forth between sent and received messages in the header data (as specified by SMS protocol) from which the client device can properly thread an incoming message to a specific dialogue, or even to a specific message within a dialogue. Most smart phone text-messaging-clients are able to create some contextual threading of "group messages" which narrows the context of the thread around the common interests shared by

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  • Adobe PhotoDeluxe

    Adobe PhotoDeluxe

    PhotoDeluxe was a consumer-oriented image editing software line published by Adobe Systems from 1996 until July 8, 2002. At that time it was replaced by Adobe's newly launched consumer-oriented image editing software Photoshop Elements. Adobe no longer provides technical support for the PhotoDeluxe software line. PhotoDeluxe had a range of image processing capabilities for the home photographer and image handler. These included removing red-eye, cropping, and adjusting brightness, contrast, and sharpness. It also included software to extract pictures from an image scanner. Among the functionality included was the ability to dynamically resize photos and export them in a wide range of formats. It also had a range of printing options including printing multiple copies of an image on the same page. It was often bundled free with Epson scanners or as free software with new computers. == Features == Despite the critical concerns regarding the quality of the setup, Photo Deluxe supports layering, blurs, sharpening, cloning, gradient fills, color and background switches, color variations, resizing options, and many other features. Another drawback of PhotoDeluxe was that it was designed for Mac computers, so working on Windows PC was a problem for those who were unable to customize their preferences. == Versions == === Adobe PhotoDeluxe 1.0 === The first version was released in 1996 for Windows and Macintosh computers. In one year, it sold over one million copies. === Adobe PhotoDeluxe 2.0 === The new version was released in 1997 and had added features such as a Clone Tool, red-eye removal, and sample templates for making posters, cards, and calendars. It also had new special effect features. === Adobe PhotoDeluxe 3.0 === The 3rd version was released in 1998. The new features included customizable clipart settings, the ability to import photos on the web, enhanced repair activities following Guided Activities, and Adobe Connectables to add new activities. === Adobe PhotoDeluxe Home Edition (4.0) === Version 4.0 was created by the makers of Photoshop. It had advanced abilities such as tools to add animation, voice, and music to a picture. It also had features to restore photos to their original position. == History == Adobe PhotoDeluxe 1.0 was released in 1996 for Macintosh computers, initially retailing for an MSRP of $49. The software did quite well, reportedly selling over a million copies by February of the next year, primarily due to bundles with companies like Apple and Hewlett-Packard. PhotoDeluxe was primarily advertised to consumers as a way to do basic photo manipulation, such as cropping and rotating images, or creating simple cards and calendars. PhotoDeluxe 2.0 was released in 1997, and was the last version of PhotoDeluxe that Adobe made that worked on Macs. PhotoDeluxe 2.0 became the "number one selling consumer photo-editing software product in the world." PhotoDeluxe 3.0 was released in 1998, where it was rebranded as "3.0 Home Edition", as Adobe released PhotoDeluxe Business Edition later that year for a higher price. PhotoDeluxe Home Edition, unofficially called PhotoDeluxe 4.0, was released in 1999 and was the last version of PhotoDeluxe to be released. Adobe officially cancelled PhotoDeluxe on July 8, 2002, citing the presence of Photoshop and Photoshop Elements, with support being officially cancelled in mid-2003. No version of PhotoDeluxe is compatible with Windows 10, rendering the program obsolete. == Pricing == All home versions of PhotoDeluxe retailed for an MSRP of $49. PhotoDeluxe 2.0 and onwards allowed users to upgrade from a previous version of PhotoDeluxe or a competing piece of graphics software for $39. Additionally PhotoDeluxe Business Edition allowed a similar deal, allowing users to upgrade from other versions of PhotoDeluxe or a competing software for $59, instead of its normal price of $99. Adobe also offered a bundle allowing users of 1.0 or 2.0 to get 3.0 and Business Edition for $79.

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  • Inductive programming

    Inductive programming

    Inductive programming (IP) is a special area of automatic programming, covering research from artificial intelligence and programming, which addresses learning of typically declarative (logic or functional) and often recursive programs from incomplete specifications, such as input/output examples or constraints. Depending on the programming language used, there are several kinds of inductive programming. Inductive functional programming, which uses functional programming languages such as Lisp or Haskell, and most especially inductive logic programming, which uses logic programming languages such as Prolog and other logical representations such as description logics, have been more prominent, but other (programming) language paradigms have also been used, such as constraint programming or probabilistic programming. == Definition == Inductive programming incorporates all approaches which are concerned with learning programs or algorithms from incomplete (formal) specifications. Possible inputs in an IP system are a set of training inputs and corresponding outputs or an output evaluation function, describing the desired behavior of the intended program, traces or action sequences which describe the process of calculating specific outputs, constraints for the program to be induced concerning its time efficiency or its complexity, various kinds of background knowledge such as standard data types, predefined functions to be used, program schemes or templates describing the data flow of the intended program, heuristics for guiding the search for a solution or other biases. Output of an IP system is a program in some arbitrary programming language containing conditionals and loop or recursive control structures, or any other kind of Turing-complete representation language. In many applications the output program must be correct with respect to the examples and partial specification, and this leads to the consideration of inductive programming as a special area inside automatic programming or program synthesis, usually opposed to 'deductive' program synthesis, where the specification is usually complete. In other cases, inductive programming is seen as a more general area where any declarative programming or representation language can be used and we may even have some degree of error in the examples, as in general machine learning, the more specific area of structure mining or the area of symbolic artificial intelligence. A distinctive feature is the number of examples or partial specification needed. Typically, inductive programming techniques can learn from just a few examples. The diversity of inductive programming usually comes from the applications and the languages that are used: apart from logic programming and functional programming, other programming paradigms and representation languages have been used or suggested in inductive programming, such as functional logic programming, constraint programming, probabilistic programming, abductive logic programming, modal logic, action languages, agent languages and many types of imperative languages. == History == The early works of Plotkin, and his "relative least general generalization (rlgg)", had an enormous impact in inductive logic programming. There were some encouraging results on learning recursive Prolog programs such as quicksort from examples together with suitable background knowledge, for example with GOLEM. However, after initial success, the community got disappointed by limited progress about the induction of recursive programs with ILP less and less focusing on recursive programs and leaning more and more towards a machine learning setting with applications in relational data mining and knowledge discovery. In parallel to work in ILP, Koza proposed genetic programming in the early 1990s as a generate-and-test based approach to learning programs. The idea of genetic programming was further developed into the inductive programming system ADATE and the systematic-search-based system MagicHaskeller. Here again, functional programs are learned from sets of positive examples together with an output evaluation (fitness) function which specifies the desired input/output behavior of the program to be learned. The early work in grammar induction (also known as grammatical inference) is related to inductive programming, as rewriting systems or logic programs can be used to represent production rules. In fact, early works in inductive inference considered grammar induction and Lisp program inference as basically the same problem. The results in terms of learnability were related to classical concepts, such as identification-in-the-limit, as introduced in the seminal work of Gold. More recently, the language learning problem was addressed by the inductive programming community. In the recent years, the classical approaches have been resumed and advanced with great success. Therefore, the synthesis problem has been reformulated on the background of constructor-based term rewriting systems taking into account modern techniques of functional programming, as well as moderate use of search-based strategies and usage of background knowledge as well as automatic invention of subprograms. Many new and successful applications have recently appeared beyond program synthesis, most especially in the area of data manipulation, programming by example and cognitive modelling (see below). Other ideas have also been explored with the common characteristic of using declarative languages for the representation of hypotheses. For instance, the use of higher-order features, schemes or structured distances have been advocated for a better handling of recursive data types and structures; abstraction has also been explored as a more powerful approach to cumulative learning and function invention. One powerful paradigm that has been recently used for the representation of hypotheses in inductive programming (generally in the form of generative models) is probabilistic programming (and related paradigms, such as stochastic logic programs and Bayesian logic programming). == Application areas == The first workshop on Approaches and Applications of Inductive Programming (AAIP) Archived 2016-03-03 at the Wayback Machine held in conjunction with ICML 2005 identified all applications where "learning of programs or recursive rules are called for, [...] first in the domain of software engineering where structural learning, software assistants and software agents can help to relieve programmers from routine tasks, give programming support for end users, or support of novice programmers and programming tutor systems. Further areas of application are language learning, learning recursive control rules for AI-planning, learning recursive concepts in web-mining or for data-format transformations". Since then, these and many other areas have shown to be successful application niches for inductive programming, such as end-user programming, the related areas of programming by example and programming by demonstration, and intelligent tutoring systems. Other areas where inductive inference has been recently applied are knowledge acquisition, artificial general intelligence, reinforcement learning and theory evaluation, and cognitive science in general. There may also be prospective applications in intelligent agents, games, robotics, personalisation, ambient intelligence and human interfaces.

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  • Biohybrid microswimmer

    Biohybrid microswimmer

    A biohybrid microswimmer also known as biohybrid nanorobot, can be defined as a microswimmer that consist of both biological and artificial constituents, for instance, one or several living microorganisms attached to one or various synthetic parts. In recent years nanoscopic and mesoscopic objects have been designed to collectively move through direct inspiration from nature or by harnessing its existing tools. Small mesoscopic to nanoscopic systems typically operate at low Reynolds numbers (Re ≪ 1), and understanding their motion becomes challenging. For locomotion to occur, the symmetry of the system must be broken. In addition, collective motion requires a coupling mechanism between the entities that make up the collective. To develop mesoscopic to nanoscopic entities capable of swarming behaviour, it has been hypothesised that the entities are characterised by broken symmetry with a well-defined morphology, and are powered with some material capable of harvesting energy. If the harvested energy results in a field surrounding the object, then this field can couple with the field of a neighbouring object and bring some coordination to the collective behaviour. Such robotic swarms have been categorised by an online expert panel as among the 10 great unresolved group challenges in the area of robotics. Although investigation of their underlying mechanism of action is still in its infancy, various systems have been developed that are capable of undergoing controlled and uncontrolled swarming motion by harvesting energy (e.g., light, thermal, etc.). Over the past decade, biohybrid microrobots, in which living mobile microorganisms are physically integrated with untethered artificial structures, have gained growing interest to enable the active locomotion and cargo delivery to a target destination. In addition to the motility, the intrinsic capabilities of sensing and eliciting an appropriate response to artificial and environmental changes make cell-based biohybrid microrobots appealing for transportation of cargo to the inaccessible cavities of the human body for local active delivery of diagnostic and therapeutic agents. == Background == Biohybrid microswimmers can be defined as microswimmers that consist of both biological and artificial constituents, for instance, one or several living microorganisms attached to one or various synthetic parts. The pioneers of this field, ahead of their time, were Montemagno and Bachand with a 1999 work regarding specific attachment strategies of biological molecules to nanofabricated substrates enabling the preparation of hybrid inorganic/organic nanoelectromechanical systems, so called NEMS. They described the production of large amounts of F1-ATPase from the thermophilic bacteria Bacillus PS3 for the preparation of F1-ATPase biomolecular motors immobilized on a nanoarray pattern of gold, copper or nickel produced by electron beam lithography. These proteins were attached to one micron microspheres tagged with a synthetic peptide. Consequently, they accomplished the preparation of a platform with chemically active sites and the development of biohybrid devices capable of converting energy of biomolecular motors into useful work. One of the most fundamental questions in science is what defines life. Collective motion is one of the hallmarks of life. This is commonly observed in nature at various dimensional levels as energized entities gather, in a concerted effort, into motile aggregated patterns. These motile aggregated events can be noticed, among many others, as dynamic swarms; e.g., unicellular organisms such as bacteria, locust swarms, or the flocking behaviour of birds. Ever since Newton established his equations of motion, the mystery of motion on the microscale has emerged frequently in scientific history, as famously demonstrated by a couple of articles that should be discussed briefly. First, an essential concept, popularized by Osborne Reynolds, is that the relative importance of inertia and viscosity for the motion of a fluid depends on certain details of the system under consideration. The Reynolds number Re, named in his honor, quantifies this comparison as a dimensionless ratio of characteristic inertial and viscous forces: R e = ρ u l μ {\displaystyle \mathrm {Re} ={\frac {\rho ul}{\mu }}} Here, ρ represents the density of the fluid; u is a characteristic velocity of the system (for instance, the velocity of a swimming particle); l is a characteristic length scale (e.g., the swimmer size); and μ is the viscosity of the fluid. Taking the suspending fluid to be water, and using experimentally observed values for u, one can determine that inertia is important for macroscopic swimmers like fish (Re = 100), while viscosity dominates the motion of microscale swimmers like bacteria (Re = 10−4). The overwhelming importance of viscosity for swimming at the micrometer scale has profound implications for swimming strategy. This has been discussed memorably by E. M. Purcell, who invited the reader into the world of microorganisms and theoretically studied the conditions of their motion. In the first place, propulsion strategies of large scale swimmers often involve imparting momentum to the surrounding fluid in periodic discrete events, such as vortex shedding, and coasting between these events through inertia. This cannot be effective for microscale swimmers like bacteria: due to the large viscous damping, the inertial coasting time of a micron-sized object is on the order of 1 μs. The coasting distance of a microorganism moving at a typical speed is about 0.1 angstroms (Å). Purcell concluded that only forces that are exerted in the present moment on a microscale body contribute to its propulsion, so a constant energy conversion method is essential. Microorganisms have optimized their metabolism for continuous energy production, while purely artificial microswimmers (microrobots) must obtain energy from the environment, since their on-board-storage-capacity is very limited. As a further consequence of the continuous dissipation of energy, biological and artificial microswimmers do not obey the laws of equilibrium statistical physics, and need to be described by non-equilibrium dynamics. Mathematically, Purcell explored the implications of low Reynolds number by taking the Navier-Stokes equation and eliminating the inertial terms: μ ∇ 2 u − ∇ p = 0 {\displaystyle {\begin{aligned}\mu \nabla ^{2}\mathbf {u} -{\boldsymbol {\nabla }}p&={\boldsymbol {0}}\\\end{aligned}}} where u {\displaystyle \mathbf {u} } is the velocity of the fluid and ∇ p {\displaystyle {\boldsymbol {\nabla }}p} is the gradient of the pressure. As Purcell noted, the resulting equation — the Stokes equation — contains no explicit time dependence. This has some important consequences for how a suspended body (e.g., a bacterium) can swim through periodic mechanical motions or deformations (e.g., of a flagellum). First, the rate of motion is practically irrelevant for the motion of the microswimmer and of the surrounding fluid: changing the rate of motion will change the scale of the velocities of the fluid and of the microswimmer, but it will not change the pattern of fluid flow. Secondly, reversing the direction of mechanical motion will simply reverse all velocities in the system. These properties of the Stokes equation severely restrict the range of feasible swimming strategies. Recent publications of biohybrid microswimmers include the use of sperm cells, contractive muscle cells, and bacteria as biological components, as they can efficiently convert chemical energy into movement, and additionally are capable of performing complicated motion depending on environmental conditions. In this sense, biohybrid microswimmer systems can be described as the combination of different functional components: cargo and carrier. The cargo is an element of interest to be moved (and possibly released) in a customized way. The carrier is the component responsible for the movement of the biohybrid, transporting the desired cargo, which is linked to its surface. The great majority of these systems rely on biological motile propulsion for the transportation of synthetic cargo for targeted drug delivery/ There are also examples of the opposite case: artificial microswimmers with biological cargo systems. Over the past decade, biohybrid microrobots, in which living mobile microorganisms are physically integrated with untethered artificial structures, have gained growing interest to enable the active locomotion and cargo delivery to a target destination. In addition to the motility, the intrinsic capabilities of sensing and eliciting an appropriate response to artificial and environmental changes make cell-based biohybrid microrobots appealing for transportation of cargo to the inaccessible cavities of the human body for local active delivery of diagnostic and therapeutic agents. Active locomotion, targeting and steering of concentrated therape

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  • Graphics suite

    Graphics suite

    A graphics suite is a software suite for graphics work that are distributed together. The programs are usually able to interact with each other on a higher level than the operating system would normally allow. There is no hard, fast rule regarding the programs to be included in a graphics application suite, but most will include at least a bitmap graphics editor and a vector graphics editor. In addition to these, the suite may contain VRML editors, animation editors, and morphing tools.

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