Deep tomographic reconstruction

Deep Tomographic Reconstruction is a set of methods for using deep learning methods to perform tomographic reconstruction of medical and industrial images. It uses artificial intelligence and machine learning, especially deep artificial neural networks or deep learning, to overcome challenges such as measurement noise, data sparsity, image artifacts, and computational inefficiency. This approach has been applied across various imaging modalities, including CT, MRI, PET, SPECT, ultrasound, and optical imaging == Historical background == Traditional tomographic reconstruction relies on analytic methods such as filtered back-projection, or iterative methods which incrementally compute inverse transformations from measurement data (e.g., Radon or Fourier transform data). However, these approaches are not sufficient for certain imaging techniques such as low-dose CT and fast MRI, or scenarios involving metal artifacts and patient motion. == Use in imaging modalities == === Computed tomography (CT) === In CT, deep learning models can be particularly effective in reducing radiation exposure while maintaining image quality. Deep neural networks can also be able to reconstruct images of fair quality from sparsely sampled data without sacrificing diagnostic performance. Deep learning-based generative AI models can reduce CT metal artifacts. === Magnetic resonance imaging (MRI) === In magnetic resonance imaging (MRI), deep learning can lead to reduced MRI motion artifacts, and increased acquisition speed, referred to as fast MRI. Despite suffering from disadvantages such as lower signal-to-noise ratio (SNR), deep learning can enhance image quality in low field MRI, making these systems clinically viable. === Positron emission tomography (PET) and single-photon emission CT (SPECT) === For PET imaging, deep learning models can provide substantial improvements in low-dose imaging and motion artifact correction. Also, deep learning can help SPECT for generation of attenuation background. A notable technique for PET denoising involves integrating MR data through multimodal networks, which use anatomical information from MRI to enhance PET image quality. === Ultrasound imaging === Deep learning can enhance ultrasound imaging by reducing speckle noise and motion blur. For ultrasound beamforming, deep neural networks can allow superior image quality with limited data at high speed. === Optical imaging and microscopy === Diffuse optical tomography, optical coherence tomography and microscopy can be improved by deep neural networks beyond traditional methods. Furthermore, deep learning can also enhance Photoacoustic imaging (see Deep learning in photoacoustic imaging), addressing challenges like high noise, low contrast, and limited resolution. Deep learning has also been applied to label-free live-cell imaging, where convolutional neural networks predict fluorescence labels from transmitted light images, a technique known as in silico labeling. This method can enable high-throughput, non-invasive cell analysis and phenotyping without the need for traditional fluorescent dyes.

AI Voice Assistants: Free vs Paid (2026)

Shopping for the best AI voice assistant? An AI voice assistant is software that uses machine learning to help you get more done — it keeps getting smarter as the underlying models improve. Pricing, accuracy, and the size of the model behind the tool are the three factors that most affect daily usefulness. Whether you are a beginner or a pro, the right AI voice assistant slots into your workflow and pays for itself fast. We tested the leading options and ranked them by quality, value, and ease of use.

AI-complete

In the field of artificial intelligence (AI), tasks that are hypothesized to require artificial general intelligence to solve are informally known as AI-complete or AI-hard. Calling a problem AI-complete reflects the belief that it cannot be solved by a simple specific algorithm. Prior to 2013, problems supposed to be AI-complete included computer vision, natural language understanding, and dealing with unexpected circumstances while solving any real-world problem. AI-complete tasks were notably considered useful for distinguishing humans from automated agents, as CAPTCHAs aim to do. == History == The term was coined by Fanya Montalvo by analogy with NP-complete and NP-hard in complexity theory, which formally describes the most famous class of difficult problems. Early uses of the term are in Erik Mueller's 1987 PhD dissertation and in Eric Raymond's 1991 Jargon File. Expert systems, that were popular in the 1980s, were able to solve very simple and/or restricted versions of AI-complete problems, but never in their full generality. When AI researchers attempted to "scale up" their systems to handle more complicated, real-world situations, the programs tended to become excessively brittle without commonsense knowledge or a rudimentary understanding of the situation: they would fail as unexpected circumstances outside of its original problem context would begin to appear. When human beings are dealing with new situations in the world, they are helped by their awareness of the general context: they know what the things around them are, why they are there, what they are likely to do and so on. They can recognize unusual situations and adjust accordingly. Expert systems lacked this adaptability and were brittle when facing new situations. DeepMind published a work in May 2022 in which they trained a single model to do several things at the same time. The model, named Gato, can "play Atari, caption images, chat, stack blocks with a real robot arm and much more, deciding based on its context whether to output text, joint torques, button presses, or other tokens." Similarly, some tasks once considered to be AI-complete, like machine translation, are among the capabilities of large language models. == AI-complete problems == AI-complete problems have been hypothesized to include: AI peer review (composite natural language understanding, automated reasoning, automated theorem proving, formalized logic expert system) Bongard problems Computer vision (and subproblems such as object recognition) Natural language understanding (and subproblems such as text mining, machine translation, and word-sense disambiguation) Autonomous driving Dealing with unexpected circumstances while solving any real world problem, whether navigation, planning, or even the kind of reasoning done by expert systems. == Formalization == Computational complexity theory deals with the relative computational difficulty of computable functions. By definition, it does not cover problems whose solution is unknown or has not been characterized formally. Since many AI problems have no formalization yet, conventional complexity theory does not enable a formal definition of AI-completeness. == Research == Roman Yampolskiy suggests that a problem C {\displaystyle C} is AI-Complete if it has two properties: It is in the set of AI problems (Human Oracle-solvable). Any AI problem can be converted into C {\displaystyle C} by some polynomial time algorithm. On the other hand, a problem H {\displaystyle H} is AI-Hard if and only if there is an AI-Complete problem C {\displaystyle C} that is polynomial time Turing-reducible to H {\displaystyle H} . This also gives as a consequence the existence of AI-Easy problems, that are solvable in polynomial time by a deterministic Turing machine with an oracle for some problem. Yampolskiy has also hypothesized that the Turing Test is a defining feature of AI-completeness. Groppe and Jain classify problems which require artificial general intelligence to reach human-level machine performance as AI-complete, while only restricted versions of AI-complete problems can be solved by the current AI systems. For Šekrst, getting a polynomial solution to AI-complete problems would not necessarily be equal to solving the issue of artificial general intelligence, while emphasizing the lack of computational complexity research being the limiting factor towards achieving artificial general intelligence. For Kwee-Bintoro and Velez, solving AI-complete problems would have strong repercussions on society.

Neural scaling law

In machine learning, a neural scaling law is an empirical scaling law that describes how neural network performance changes as key factors are scaled up or down. These factors typically include the number of parameters, training dataset size, and training cost. Some models also exhibit performance gains by scaling inference through increased test-time compute (TTC), extending neural scaling laws beyond training to the deployment phase. == Introduction == In general, a deep learning model can be characterized by four parameters: model size, training dataset size, training cost, and the post-training error rate (e.g., the test set error rate). Each of these variables can be defined as a real number, usually written as N , D , C , L {\displaystyle N,D,C,L} (respectively: parameter count, dataset size, computing cost, and loss). A neural scaling law is a theoretical or empirical statistical law between these parameters. There are also other parameters with other scaling laws. === Size of the model === In most cases, the model's size is simply the number of parameters. However, one complication arises with the use of sparse models, such as mixture-of-expert models. With sparse models, during inference, only a fraction of their parameters are used. In comparison, most other kinds of neural networks, such as transformer models, always use all their parameters during inference. === Size of the training dataset === The size of the training dataset is usually quantified by the number of data points within it. Larger training datasets are typically preferred, as they provide a richer and more diverse source of information from which the model can learn. This can lead to improved generalization performance when the model is applied to new, unseen data. However, increasing the size of the training dataset also increases the computational resources and time required for model training. With the "pretrain, then finetune" method used for most large language models, there are two kinds of training dataset: the pretraining dataset and the finetuning dataset. Their sizes have different effects on model performance. Generally, the finetuning dataset is less than 1% the size of pretraining dataset. In some cases, a small amount of high quality data suffices for finetuning, and more data does not necessarily improve performance. Many scaling laws, due to their inherent diminishing returns nature, value data based on a submodular set function which was shown in a paper on this topic. === Cost of training === Training cost is typically measured in terms of time (how long it takes to train the model) and computational resources (how much processing power and memory are required). It is important to note that the cost of training can be significantly reduced with efficient training algorithms, optimized software libraries, and parallel computing on specialized hardware such as GPUs or TPUs. The cost of training a neural network model is a function of several factors, including model size, training dataset size, the training algorithm complexity, and the computational resources available. In particular, doubling the training dataset size does not necessarily double the cost of training, because one may train the model for several times over the same dataset (each being an "epoch"). === Performance === The performance of a neural network model is evaluated based on its ability to accurately predict the output given some input data. Common metrics for evaluating model performance include: Negative log-likelihood per token (logarithm of perplexity) for language modeling; Accuracy, precision, recall, and F1 score for classification tasks; Mean squared error (MSE) or mean absolute error (MAE) for regression tasks; Elo rating in a competition against other models, such as gameplay or preference by a human judge. Performance can be improved by using more data, larger models, different training algorithms, regularizing the model to prevent overfitting, and early stopping using a validation set. When the performance is a number bounded within the range of [ 0 , 1 ] {\displaystyle [0,1]} , such as accuracy, precision, etc., it often scales as a sigmoid function of cost, as seen in the figures. == Examples == === (Hestness, Narang, et al, 2017) === The 2017 paper is a common reference point for neural scaling laws fitted by statistical analysis on experimental data. Previous works before the 2000s, as cited in the paper, were either theoretical or orders of magnitude smaller in scale. Whereas previous works generally found the scaling exponent to scale like L ∝ D − α {\displaystyle L\propto D^{-\alpha }} , with α ∈ { 0.5 , 1 , 2 } {\displaystyle \alpha \in \{0.5,1,2\}} , the paper found that α ∈ [ 0.07 , 0.35 ] {\displaystyle \alpha \in [0.07,0.35]} . Of the factors they varied, only task can change the exponent α {\displaystyle \alpha } . Changing the architecture optimizers, regularizers, and loss functions, would only change the proportionality factor, not the exponent. For example, for the same task, one architecture might have L = 1000 D − 0.3 {\displaystyle L=1000D^{-0.3}} while another might have L = 500 D − 0.3 {\displaystyle L=500D^{-0.3}} . They also found that for a given architecture, the number of parameters necessary to reach lowest levels of loss, given a fixed dataset size, grows like N ∝ D β {\displaystyle N\propto D^{\beta }} for another exponent β {\displaystyle \beta } . They studied machine translation with LSTM ( α ∼ 0.13 {\displaystyle \alpha \sim 0.13} ), generative language modelling with LSTM ( α ∈ [ 0.06 , 0.09 ] , β ≈ 0.7 {\displaystyle \alpha \in [0.06,0.09],\beta \approx 0.7} ), ImageNet classification with ResNet ( α ∈ [ 0.3 , 0.5 ] , β ≈ 0.6 {\displaystyle \alpha \in [0.3,0.5],\beta \approx 0.6} ), and speech recognition with two hybrid (LSTMs complemented by either CNNs or an attention decoder) architectures ( α ≈ 0.3 {\displaystyle \alpha \approx 0.3} ). === (Henighan, Kaplan, et al, 2020) === A 2020 analysis studied statistical relations between C , N , D , L {\displaystyle C,N,D,L} over a wide range of values and found similar scaling laws, over the range of N ∈ [ 10 3 , 10 9 ] {\displaystyle N\in [10^{3},10^{9}]} , C ∈ [ 10 12 , 10 21 ] {\displaystyle C\in [10^{12},10^{21}]} , and over multiple modalities (text, video, image, text to image, etc.). In particular, the scaling laws it found are (Table 1 of ): For each modality, they fixed one of the two C , N {\displaystyle C,N} , and varying the other one ( D {\displaystyle D} is varied along using D = C / 6 N {\displaystyle D=C/6N} ), the achievable test loss satisfies L = L 0 + ( x 0 x ) α {\displaystyle L=L_{0}+\left({\frac {x_{0}}{x}}\right)^{\alpha }} where x {\displaystyle x} is the varied variable, and L 0 , x 0 , α {\displaystyle L_{0},x_{0},\alpha } are parameters to be found by statistical fitting. The parameter α {\displaystyle \alpha } is the most important one. When N {\displaystyle N} is the varied variable, α {\displaystyle \alpha } ranges from 0.037 {\displaystyle 0.037} to 0.24 {\displaystyle 0.24} depending on the model modality. This corresponds to the α = 0.34 {\displaystyle \alpha =0.34} from the Chinchilla scaling paper. When C {\displaystyle C} is the varied variable, α {\displaystyle \alpha } ranges from 0.048 {\displaystyle 0.048} to 0.19 {\displaystyle 0.19} depending on the model modality. This corresponds to the β = 0.28 {\displaystyle \beta =0.28} from the Chinchilla scaling paper. Given fixed computing budget, optimal model parameter count is consistently around N o p t ( C ) = ( C 5 × 10 − 12 petaFLOP-day ) 0.7 = 9.0 × 10 − 7 C 0.7 {\displaystyle N_{opt}(C)=\left({\frac {C}{5\times 10^{-12}{\text{petaFLOP-day}}}}\right)^{0.7}=9.0\times 10^{-7}C^{0.7}} The parameter 9.0 × 10 − 7 {\displaystyle 9.0\times 10^{-7}} varies by a factor of up to 10 for different modalities. The exponent parameter 0.7 {\displaystyle 0.7} varies from 0.64 {\displaystyle 0.64} to 0.75 {\displaystyle 0.75} for different modalities. This exponent corresponds to the ≈ 0.5 {\displaystyle \approx 0.5} from the Chinchilla scaling paper. It's "strongly suggested" (but not statistically checked) that D o p t ( C ) ∝ N o p t ( C ) 0.4 ∝ C 0.28 {\displaystyle D_{opt}(C)\propto N_{opt}(C)^{0.4}\propto C^{0.28}} . This exponent corresponds to the ≈ 0.5 {\displaystyle \approx 0.5} from the Chinchilla scaling paper. The scaling law of L = L 0 + ( C 0 / C ) 0.048 {\displaystyle L=L_{0}+(C_{0}/C)^{0.048}} was confirmed during the training of GPT-3 (Figure 3.1 ). === Chinchilla scaling (Hoffmann, et al, 2022) === One particular scaling law ("Chinchilla scaling") states that, for a large language model (LLM) autoregressively trained for one epoch, with a cosine learning rate schedule, we have: { C = C 0 N D L = A N α + B D β + L 0 {\displaystyle {\begin{cases}C=C_{0}ND\\L={\frac {A}{N^{\alpha }}}+{\frac {B}{D^{\beta }}}+L_{0}\end{cases}}} where the variables are C {\displaystyle C} is the cost o

Hello World: How to be Human in the Age of the Machine

Hello World: How to Be Human in the Age of the Machine (also titled Hello World: Being Human in the Age of Algorithms) is a book on the growing influence of algorithms and artificial intelligence (AI) on human life, authored by mathematician and science communicator Hannah Fry. The book examines how algorithms are increasingly shaping decisions in critical areas such as healthcare, transportation, justice, finance, and the arts. == Overview == Fry uses real-world examples, such as driverless cars and predictive policing, to illustrate her points. She emphasizes that algorithms are not inherently objective; they reflect biases embedded in their design and data inputs. While acknowledging their potential to improve efficiency and accuracy, Fry cautions against over-reliance on machines without human judgment. Fry explores moral questions surrounding algorithmic decision-making, such as whether machines can replace human empathy in critical situations. She advocates for greater scrutiny of algorithms to ensure fairness and avoid harmful biases. The book proposes a "cyborg future", where humans work alongside algorithms to enhance decision-making while retaining ultimate control. == Reception == Hello World has been praised for its clarity, engaging storytelling, and balanced perspective. Critics have highlighted Fry's ability to make complex topics accessible to general audiences while raising important questions about technology's impact on society. The book was shortlisted for awards such as the 2018 Baillie Gifford Prize and the Royal Society Science Book Prize.

Algorithmic probability

In algorithmic information theory, algorithmic probability, also known as Solomonoff probability, is a mathematical method of assigning a prior probability to a given observation. It was invented by Ray Solomonoff in the 1960s. It is used in inductive inference theory and analyses of algorithms. In his general theory of inductive inference, Solomonoff uses the method together with Bayes' rule to obtain probabilities of prediction for an algorithm's future outputs. In the mathematical formalism used, the observations have the form of finite binary strings viewed as outputs of Turing machines, and the universal prior is a probability distribution over the set of finite binary strings calculated from a probability distribution over programs (that is, inputs to a universal Turing machine). The prior is universal in the Turing-computability sense, i.e. no string has zero probability. It is not computable, but it can be approximated. Formally, the probability P {\displaystyle P} is not a probability and it is not computable. It is only "lower semi-computable" and a "semi-measure". By "semi-measure", it means that 0 ≤ ∑ x P ( x ) < 1 {\displaystyle 0\leq \sum _{x}P(x)<1} . That is, the "probability" does not actually sum up to one, unlike actual probabilities. This is because some inputs to the Turing machine causes it to never halt, which means the probability mass allocated to those inputs is lost. By "lower semi-computable", it means there is a Turing machine that, given an input string x {\displaystyle x} , can print out a sequence y 1 < y 2 < ⋯ {\displaystyle y_{1}

Autonomous agent

An autonomous agent is an artificial intelligence (AI) system that can perform complex tasks independently. == Definitions == There are various definitions of autonomous agent. According to Brustoloni (1991): "Autonomous agents are systems capable of autonomous, purposeful action in the real world." According to Maes (1995): "Autonomous agents are computational systems that inhabit some complex dynamic environment, sense and act autonomously in this environment, and by doing so realize a set of goals or tasks for which they are designed." Franklin and Graesser (1997) review different definitions and propose their definition: "An autonomous agent is a system situated within and a part of an environment that senses that environment and acts on it, over time, in pursuit of its own agenda and so as to effect what it senses in the future." They explain that: "Humans and some animals are at the high end of being an agent, with multiple, conflicting drives, multiples senses, multiple possible actions, and complex sophisticated control structures. At the low end, with one or two senses, a single action, and an absurdly simple control structure we find a thermostat." == Agent appearance == Lee et al. (2015) post safety issue from how the combination of external appearance and internal autonomous agent have impact on human reaction about autonomous vehicles. Their study explores the human-like appearance agent and high level of autonomy are strongly correlated with social presence, intelligence, safety and trustworthiness. In specific, appearance impacts most on affective trust while autonomy impacts most on both affective and cognitive domain of trust where cognitive trust is characterized by knowledge-based factors and affective trust is largely emotion driven. == Applications == Agentic AI systems: Advanced AI agents that can scope out projects and complete them with necessary tools, representing a significant evolution from simple task-oriented systems. Internet of things (IoT) Integration: Autonomous agents increasingly interact with IoT devices, enabling smart home systems, industrial monitoring, and urban infrastructure management. Collaborative software development: Tools like Cognition AI's Devin aim to create autonomous software engineers capable of complex reasoning, planning, and completing engineering tasks requiring thousands of decisions. Enterprise automation: Business process automation platforms like Salesforce's Agentforce provide autonomous bots for various service functions. == Challenges and considerations == Uncertainty and incomplete information: Autonomous agents must make decisions with limited or uncertain information about their environment and future states. Integration complexity: Incorporating autonomous agents into existing systems and workflows can be technically challenging and resource-intensive. Scalability: As systems become more complex and more agents are used, maintaining coordination and avoiding conflicts becomes increasingly difficult. Trust: Research has shown the combination of external appearance and internal autonomous capabilities significantly impacts human reactions and trust. Lee et al. (2015) found that human-like appearance and high levels of autonomy are strongly correlated with social presence, intelligence, safety, and trustworthiness perceptions. Specifically, appearance impacts affective trust most significantly, while autonomy affects both affective and cognitive trust domains, where affective trust is emotionally driven, and cognitive trust is characterized by knowledge-based factors. Vulnerability to manipulation: Researchers from Harvard, MIT and other educational institutions found that AI agents could become vulnerable to manipulation and could perform detrimental actions in the process of being helpful. == Ethical and regulatory concerns == Accountability: Determining responsibility when autonomous agents make incorrect or harmful decisions remains a complex issue. Privacy and security: autonomous agents often require access to sensitive data, raising concerns about data protection and system security.